LOCUS       DAVAGB010000001       133581 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVAGB010000001 DAVAGB010000000
VERSION     DAVAGB010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 133581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 133581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..133581
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.001"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(408..1619)
                     /locus_tag="VQO19_000001"
     CDS             complement(408..1619)
                     /locus_tag="VQO19_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348329.1"
                     /translation="MKKVIEMFPEFHQEKLETTDIKDENNLIVVDTNFLLQILELPID
                     IATKYVDSLKSIKRNLYIPYLVALEFHFNKSNKKKTKKRNADSYFKQVESALNQLKSS
                     VQNTDLIKMDIENGKLKHLIGNLEFFTDDFLAKVNLFVRDEITDKEDEVYKELLNIIS
                     DSIGDVYEQEWIYEIEKEGEKRFAEAIPPGFNDENKDGIRKYNGISYHQKYGDLIIWK
                     DILKKATEQPRGDKVIFITNDGESNKKSDLIYKTSNMKVGPSIFLMNELYMCSRKKLY
                     ILNNTTLVNMITELSEDEIDRIEAQEEKKYVVTFPKWILDKAEKDVRARNESNNSSVV
                     YYIDSENRLASIDIDEVEPLELISLLENPDVKKMLKEEILKKMLDGYYSKLPRHIIKD
                     IINSYQEKNIQ"
     gene            1822..2712
                     /locus_tag="VQO19_000002"
     CDS             1822..2712
                     /locus_tag="VQO19_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348330.1"
                     /translation="MDNTKVIEWLNYCDQNDIKPWLWDFKNCYSSELTADNISNFLKY
                     KNGELVNPSTFCITKQVGSNADCDKEALPLYNVLGWQHSERDIIRGETLNSYITTFTQ
                     AITNDPNYKEICKKIGVNLNEYLNKQYPILHHNKNYQNFKMIQKNLKEFEAFAKLTHT
                     IGNFTVLPHWMNTGRYNFSKDYWDITMLSLQEWLTNLSPQAWKNFIDTYYLQPYVDNN
                     YQTEVFWETHNYEYIYPKKTEDFSIFLKRVNERIEERGKFIIKQICDKLNKKDFHFYK
                     EIENMDKIKYSNEFEQERKQ"
     gene            2709..3179
                     /locus_tag="VQO19_000003"
     CDS             2709..3179
                     /locus_tag="VQO19_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348331.1"
                     /translation="MTRVYKSVRLAYEAKVWIDELIQEKERKIQELNKEDFLDKLEKT
                     LLKNHYDELNGLSFNIILKASIGSVIEESYRNTKHYPIDKWQKLRQQMERDVKNVNPN
                     LETTVTPRIYLDEDVLAGLDDFRYVLMKEDCATRLPRLSYIIKLVVYSYWKEQH"
     gene            3266..3934
                     /locus_tag="VQO19_000004"
                     /pseudo
     CDS             3266..3934
                     /locus_tag="VQO19_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476106.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
     gene            3894..5075
                     /locus_tag="VQO19_000005"
                     /pseudo
     CDS             3894..5075
                     /locus_tag="VQO19_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678337.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(5338..5730)
                     /gene="rpsI"
                     /locus_tag="VQO19_000006"
     CDS             complement(5338..5730)
                     /gene="rpsI"
                     /locus_tag="VQO19_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HET1348332.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(5750..6196)
                     /gene="rplM"
                     /locus_tag="VQO19_000007"
     CDS             complement(5750..6196)
                     /gene="rplM"
                     /locus_tag="VQO19_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HET1348333.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            6552..6869
                     /locus_tag="VQO19_000008"
     CDS             6552..6869
                     /locus_tag="VQO19_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HET1348334.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            complement(6914..7726)
                     /gene="folK"
                     /locus_tag="VQO19_000009"
     CDS             complement(6914..7726)
                     /gene="folK"
                     /locus_tag="VQO19_000009"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HET1348335.1"
                     /translation="MDQLQIKDLEIFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQVNLKQAIDKLRARGIHILKESSVLET
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(7884..8438)
                     /gene="folE"
                     /locus_tag="VQO19_000010"
     CDS             complement(7884..8438)
                     /gene="folE"
                     /locus_tag="VQO19_000010"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HET1348336.1"
                     /translation="MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMEYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(8419..9741)
                     /locus_tag="VQO19_000011"
     CDS             complement(8419..9741)
                     /locus_tag="VQO19_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET1348337.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVIHI
                     GGTNGKGSTIAFLKNMLEKLGLRVGVFSSPYLIHYTDQISINGESIPEARLEALMVDY
                     QSLLEGESAANLQGTTEFEIITAIAYDYFASEQVDVAIMEVGMGGLLDSTNVCHPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGIPLVTGRIAPEALAVIDRIAEGKDAPR
                     LVYGTDYQVSHQKSVVTGEVFDYTSVVRQGRFQTGLLGLHQIENAGMAIALLDTFCQE
                     DGRELASNHLLAQALEETSWPGRLEIVSRDPLMILDGAHNSHAIKALLATLQERFADY
                     RKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFDDSRATDENVLKEAAKSRNLSYQG
                     WQDFLEQKLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(9743..10723)
                     /gene="folP"
                     /locus_tag="VQO19_000012"
     CDS             complement(9743..10723)
                     /gene="folP"
                     /locus_tag="VQO19_000012"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HET1348338.1"
                     /translation="MVKSLEGVTDMSTKANHAKTAICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISI
                     DTWKSQVAEAALAAGANLVNDITGFMGDEKMAHVVANAGAKVVIMFNPVMARPQHPSS
                     LIFPHFGFGQAFTEEELADFEKLPIEELMETFFERALARANQAGITQENILLDPGIGF
                     GLTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDT
                     ASAHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(10817..11524)
                     /locus_tag="VQO19_000013"
     CDS             complement(10817..11524)
                     /locus_tag="VQO19_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET1348339.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGVAF
                     CLLALVVILSRTLGISV"
     gene            complement(11577..12995)
                     /locus_tag="VQO19_000014"
     CDS             complement(11577..12995)
                     /locus_tag="VQO19_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HET1348340.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            13185..13997
                     /locus_tag="VQO19_000015"
     CDS             13185..13997
                     /locus_tag="VQO19_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET1348341.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            14336..15355
                     /gene="adhP"
                     /locus_tag="VQO19_000016"
     CDS             14336..15355
                     /gene="adhP"
                     /locus_tag="VQO19_000016"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HET1348342.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIATADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLTLAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            15588..16577
                     /gene="manX"
                     /locus_tag="VQO19_000017"
     CDS             15588..16577
                     /gene="manX"
                     /locus_tag="VQO19_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HET1348343.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            16605..17408
                     /locus_tag="VQO19_000018"
     CDS             16605..17408
                     /locus_tag="VQO19_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HET1348344.1"
                     /translation="MSIISMVLVIVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            17432..18343
                     /locus_tag="VQO19_000019"
     CDS             17432..18343
                     /locus_tag="VQO19_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET1348345.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(18399..19733)
                     /gene="pepC"
                     /locus_tag="VQO19_000020"
     CDS             complement(18399..19733)
                     /gene="pepC"
                     /locus_tag="VQO19_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HET1348346.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAK"
     gene            complement(19950..20672)
                     /locus_tag="VQO19_000021"
     CDS             complement(19950..20672)
                     /locus_tag="VQO19_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET1348347.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            complement(20895..21125)
                     /locus_tag="VQO19_000022"
     CDS             complement(20895..21125)
                     /locus_tag="VQO19_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET1348348.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            complement(21135..22376)
                     /locus_tag="VQO19_000023"
     CDS             complement(21135..22376)
                     /locus_tag="VQO19_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HET1348349.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     IFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(22398..22550)
                     /locus_tag="VQO19_000024"
     CDS             complement(22398..22550)
                     /locus_tag="VQO19_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348350.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            complement(22571..22849)
                     /locus_tag="VQO19_000025"
     CDS             complement(22571..22849)
                     /locus_tag="VQO19_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HET1348351.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            complement(22842..23105)
                     /locus_tag="VQO19_000026"
     CDS             complement(22842..23105)
                     /locus_tag="VQO19_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HET1348352.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            complement(23207..27598)
                     /locus_tag="VQO19_000027"
     CDS             complement(23207..27598)
                     /locus_tag="VQO19_000027"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HET1348353.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKFLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            complement(27702..29783)
                     /gene="fusA"
                     /locus_tag="VQO19_000028"
     CDS             complement(27702..29783)
                     /gene="fusA"
                     /locus_tag="VQO19_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HET1348354.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            complement(30208..30678)
                     /gene="rpsG"
                     /locus_tag="VQO19_000029"
     CDS             complement(30208..30678)
                     /gene="rpsG"
                     /locus_tag="VQO19_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HET1348355.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            complement(30698..31111)
                     /gene="rpsL"
                     /locus_tag="VQO19_000030"
     CDS             complement(30698..31111)
                     /gene="rpsL"
                     /locus_tag="VQO19_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HET1348356.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            31528..35325
                     /gene="spuA"
                     /locus_tag="VQO19_000031"
     CDS             31528..35325
                     /gene="spuA"
                     /locus_tag="VQO19_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HET1348357.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVEIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSIPSK
                     PEHQNEASHPAYQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSV
                     KEAVQNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            complement(35425..36474)
                     /locus_tag="VQO19_000032"
     CDS             complement(35425..36474)
                     /locus_tag="VQO19_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HET1348358.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIDGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLDQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(36593..38401)
                     /gene="glmS"
                     /locus_tag="VQO19_000033"
     CDS             complement(36593..38401)
                     /gene="glmS"
                     /locus_tag="VQO19_000033"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HET1348359.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVVDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLIHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(38593..39972)
                     /gene="bglA"
                     /locus_tag="VQO19_000034"
     CDS             complement(38593..39972)
                     /gene="bglA"
                     /locus_tag="VQO19_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET1348360.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGICLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            complement(40072..41925)
                     /locus_tag="VQO19_000035"
     CDS             complement(40072..41925)
                     /locus_tag="VQO19_000035"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HET1348361.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            complement(41938..43197)
                     /gene="rseP"
                     /locus_tag="VQO19_000036"
     CDS             complement(41938..43197)
                     /gene="rseP"
                     /locus_tag="VQO19_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HET1348362.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            complement(43219..44022)
                     /locus_tag="VQO19_000037"
     CDS             complement(43219..44022)
                     /locus_tag="VQO19_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HET1348363.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            complement(44031..44789)
                     /locus_tag="VQO19_000038"
     CDS             complement(44031..44789)
                     /locus_tag="VQO19_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HET1348364.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            complement(45020..45484)
                     /locus_tag="VQO19_000039"
     CDS             complement(45020..45484)
                     /locus_tag="VQO19_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HET1348365.1"
                     /translation="MAAGSVRNFIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLE
                     KKLREDFPQYQWELKNQVYMHQHSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFE
                     LYAPYGLEDILNFQVRPTPHFLENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            complement(45573..46544)
                     /gene="ruvB"
                     /locus_tag="VQO19_000040"
     CDS             complement(45573..46544)
                     /gene="ruvB"
                     /locus_tag="VQO19_000040"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HET1348366.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            46705..46797
                     /locus_tag="VQO19_000041"
     CDS             46705..46797
                     /locus_tag="VQO19_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET1348367.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            complement(47612..48028)
                     /locus_tag="VQO19_000042"
     CDS             complement(47612..48028)
                     /locus_tag="VQO19_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET1348368.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEHALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVFVQDLIVLPIYQRQGIGSALMKEALKDYKDAYQVQ
                     LVTEETEKNVGFYRSMGFEILSTYNCIGMTWANREK"
     gene            complement(48040..48735)
                     /locus_tag="VQO19_000043"
     CDS             complement(48040..48735)
                     /locus_tag="VQO19_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET1348369.1"
                     /translation="MPVNEYGQMIGESMEGYTPGALPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLNQMLARKDRFYYAIIDKATGKALG
                     TFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYIFEELNYRRYEWKCDAL
                     NLPSRRVAERLGFVYEGTFRQAVVYKGRTRDTDWLSMIDMDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            complement(48791..49633)
                     /locus_tag="VQO19_000044"
     CDS             complement(48791..49633)
                     /locus_tag="VQO19_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348370.1"
                     /translation="MNRLVNDSRKCEILLFKISIIVVSVIVLVMSIVGAYYFKNCLWD
                     KESLNLILTLDTLFAVFITFFSFSNDKSSNIFGISPNEIIRTQSEVYQFLFTKSFATL
                     LIVTNLLSIIHYFGAKNLIVSFNETYPRIQSSVGIMWLPLFGILIIYFIWLLIEGLKY
                     IRKINYIIQNREIIYFYSQVKVVDKLTDSESKKYGEYIDLYESCRQNNLSVLLNFLQN
                     SDDKRGVIASNSVRIMFESLDKADQIAALNICRNYVARENVLNKEDAEKLLNEIDKKL
                     EISR"
     gene            complement(49772..52273)
                     /locus_tag="VQO19_000045"
     CDS             complement(49772..52273)
                     /locus_tag="VQO19_000045"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HET1348371.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAYLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVTTDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYIDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
     gene            complement(52728..53816)
                     /locus_tag="VQO19_000046"
     CDS             complement(52728..53816)
                     /locus_tag="VQO19_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HET1348372.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            complement(53834..54502)
                     /locus_tag="VQO19_000047"
     CDS             complement(53834..54502)
                     /locus_tag="VQO19_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HET1348373.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLVLAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            complement(54521..56959)
                     /locus_tag="VQO19_000048"
     CDS             complement(54521..56959)
                     /locus_tag="VQO19_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HET1348374.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            complement(57131..58429)
                     /locus_tag="VQO19_000049"
     CDS             complement(57131..58429)
                     /locus_tag="VQO19_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET1348375.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            complement(58446..58754)
                     /locus_tag="VQO19_000050"
     CDS             complement(58446..58754)
                     /locus_tag="VQO19_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET1348376.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            complement(58800..59120)
                     /locus_tag="VQO19_000051"
     CDS             complement(58800..59120)
                     /locus_tag="VQO19_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET1348377.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            complement(59315..60295)
                     /locus_tag="VQO19_000052"
     CDS             complement(59315..60295)
                     /locus_tag="VQO19_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HET1348378.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            complement(60308..61054)
                     /locus_tag="VQO19_000053"
     CDS             complement(60308..61054)
                     /locus_tag="VQO19_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET1348379.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            61176..61952
                     /locus_tag="VQO19_000054"
     CDS             61176..61952
                     /locus_tag="VQO19_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HET1348380.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            62285..62668
                     /locus_tag="VQO19_000055"
     CDS             62285..62668
                     /locus_tag="VQO19_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET1348381.1"
                     /translation="MIHKIRFEHFSYDIVCPETVDNQPIPKLFLLPLVENAIKHGMQY
                     RIDLHIDIHITLEADSLTFLVKDNAGGLTKQERFAILDSLESPHTQHGIMNSYKQLSN
                     FFSDVQLDLGVNRQGETWVKFVTKD"
     gene            62672..62899
                     /locus_tag="VQO19_000056"
     CDS             62672..62899
                     /locus_tag="VQO19_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HET1348382.1"
                     /translation="MFKLIIVEDEHLIRKWLEIAVDYSALGIQVVGTASHGQEGMKLI
                     QEKETHICLNRHHNANYGCFYDVQSHSYSFL"
     gene            62948..63181
                     /locus_tag="VQO19_000057"
     CDS             62948..63181
                     /locus_tag="VQO19_000057"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HET1348383.1"
                     /translation="MQYGAVDFLSKPIDTKELTECLQKIVLRLQISTSQETPFLEEYQ
                     TLLTSIQQVDTQNQIIQQIISFVHKHYAEHYYC"
     gene            63280..63423
                     /locus_tag="VQO19_000058"
     CDS             63280..63423
                     /locus_tag="VQO19_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET1348384.1"
                     /translation="MAESPNSPLSAISDQVGFSDYKYFAKVFKKHLHISPKELKLLGR
                     IVK"
     gene            63640..64236
                     /locus_tag="VQO19_000059"
                     /pseudo
     CDS             63640..64236
                     /locus_tag="VQO19_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            64393..64761
                     /locus_tag="VQO19_000060"
     CDS             64393..64761
                     /locus_tag="VQO19_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET1348385.1"
                     /translation="MAVGLSYEDPAVKLLNDGANIKVVYPKEGTVFLPASAAIVKKAK
                     NMENAKKFIDFIISQEVQDTLGTTTTNRPVRKNAKTSENMKPIDKIKTLTEDYDYVIK
                     NKSDIVKKYNEVFTDIQSKQ"
     gene            64774..65160
                     /locus_tag="VQO19_000061"
     CDS             64774..65160
                     /locus_tag="VQO19_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1348386.1"
                     /translation="MSEIEIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIKDGEFYFDDTKINNMEPSKRNIGLVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYAD"
     gene            65167..65256
                     /locus_tag="VQO19_000062"
                     /pseudo
     CDS             65167..65256
                     /locus_tag="VQO19_000062"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            65242..65865
                     /locus_tag="VQO19_000063"
     CDS             65242..65865
                     /locus_tag="VQO19_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1348387.1"
                     /translation="MDEPLSNLEAKLRLDMRQAIRAIQHEVGITTVYVTHDQEEAMAI
                     SDQIAAMKDGVIQQIGRPKELYHKPANEFVATFIGCTNIIPTNLEKRSDGAYIVFSDG
                     YALRMPALDQVEEQAIHVSIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASK
                     IQVSEESTFEEELQKGNRIRLRINTQKLNIFSADGSQNLIKGVNHGM"
     gene            65855..67490
                     /locus_tag="VQO19_000064"
                     /pseudo
     CDS             65855..67490
                     /locus_tag="VQO19_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(67593..68285)
                     /locus_tag="VQO19_000065"
     CDS             complement(67593..68285)
                     /locus_tag="VQO19_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET1348388.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEIIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(68529..69866)
                     /locus_tag="VQO19_000066"
     CDS             complement(68529..69866)
                     /locus_tag="VQO19_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HET1348389.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            complement(69876..70142)
                     /locus_tag="VQO19_000067"
     CDS             complement(69876..70142)
                     /locus_tag="VQO19_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HET1348390.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            complement(70407..70793)
                     /gene="rplQ"
                     /locus_tag="VQO19_000068"
     CDS             complement(70407..70793)
                     /gene="rplQ"
                     /locus_tag="VQO19_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HET1348391.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(70805..71740)
                     /locus_tag="VQO19_000069"
     CDS             complement(70805..71740)
                     /locus_tag="VQO19_000069"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HET1348392.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            complement(71783..72166)
                     /gene="rpsK"
                     /locus_tag="VQO19_000070"
     CDS             complement(71783..72166)
                     /gene="rpsK"
                     /locus_tag="VQO19_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HET1348393.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(72184..72549)
                     /gene="rpsM"
                     /locus_tag="VQO19_000071"
     CDS             complement(72184..72549)
                     /gene="rpsM"
                     /locus_tag="VQO19_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HET1348394.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(72567..72683)
                     /gene="rpmJ"
                     /locus_tag="VQO19_000072"
     CDS             complement(72567..72683)
                     /gene="rpmJ"
                     /locus_tag="VQO19_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HET1348395.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            complement(72708..72926)
                     /gene="infA"
                     /locus_tag="VQO19_000073"
     CDS             complement(72708..72926)
                     /gene="infA"
                     /locus_tag="VQO19_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HET1348396.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            complement(73043..73681)
                     /locus_tag="VQO19_000074"
     CDS             complement(73043..73681)
                     /locus_tag="VQO19_000074"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HET1348397.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHCVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            complement(73832..75142)
                     /gene="secY"
                     /locus_tag="VQO19_000075"
     CDS             complement(73832..75142)
                     /gene="secY"
                     /locus_tag="VQO19_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HET1348398.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            complement(75155..75595)
                     /gene="rplO"
                     /locus_tag="VQO19_000076"
     CDS             complement(75155..75595)
                     /gene="rplO"
                     /locus_tag="VQO19_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HET1348399.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            complement(75740..75964)
                     /gene="rpmD"
                     /locus_tag="VQO19_000077"
     CDS             complement(75740..75964)
                     /gene="rpmD"
                     /locus_tag="VQO19_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HET1348400.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            complement(75936..76430)
                     /gene="rpsE"
                     /locus_tag="VQO19_000078"
     CDS             complement(75936..76430)
                     /gene="rpsE"
                     /locus_tag="VQO19_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HET1348401.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            complement(76448..76804)
                     /gene="rplR"
                     /locus_tag="VQO19_000079"
     CDS             complement(76448..76804)
                     /gene="rplR"
                     /locus_tag="VQO19_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HET1348402.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(76888..77424)
                     /gene="rplF"
                     /locus_tag="VQO19_000080"
     CDS             complement(76888..77424)
                     /gene="rplF"
                     /locus_tag="VQO19_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HET1348403.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            complement(77616..78014)
                     /gene="rpsH"
                     /locus_tag="VQO19_000081"
     CDS             complement(77616..78014)
                     /gene="rpsH"
                     /locus_tag="VQO19_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HET1348404.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(78299..78568)
                     /gene="rpsN"
                     /locus_tag="VQO19_000082"
     CDS             complement(78299..78568)
                     /gene="rpsN"
                     /locus_tag="VQO19_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HET1348405.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            complement(78586..79128)
                     /gene="rplE"
                     /locus_tag="VQO19_000083"
     CDS             complement(78586..79128)
                     /gene="rplE"
                     /locus_tag="VQO19_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HET1348406.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            complement(79152..79457)
                     /gene="rplX"
                     /locus_tag="VQO19_000084"
     CDS             complement(79152..79457)
                     /gene="rplX"
                     /locus_tag="VQO19_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HET1348407.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            complement(79535..79903)
                     /gene="rplN"
                     /locus_tag="VQO19_000085"
     CDS             complement(79535..79903)
                     /gene="rplN"
                     /locus_tag="VQO19_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HET1348408.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            complement(79929..80189)
                     /gene="rpsQ"
                     /locus_tag="VQO19_000086"
     CDS             complement(79929..80189)
                     /gene="rpsQ"
                     /locus_tag="VQO19_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HET1348409.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            complement(80214..80420)
                     /locus_tag="VQO19_000087"
     CDS             complement(80214..80420)
                     /locus_tag="VQO19_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HET1348410.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            complement(80430..80843)
                     /gene="rplP"
                     /locus_tag="VQO19_000088"
     CDS             complement(80430..80843)
                     /gene="rplP"
                     /locus_tag="VQO19_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HET1348411.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(80847..81500)
                     /gene="rpsC"
                     /locus_tag="VQO19_000089"
     CDS             complement(80847..81500)
                     /gene="rpsC"
                     /locus_tag="VQO19_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HET1348412.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(81513..81857)
                     /gene="rplV"
                     /locus_tag="VQO19_000090"
     CDS             complement(81513..81857)
                     /gene="rplV"
                     /locus_tag="VQO19_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HET1348413.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            complement(81869..82150)
                     /gene="rpsS"
                     /locus_tag="VQO19_000091"
     CDS             complement(81869..82150)
                     /gene="rpsS"
                     /locus_tag="VQO19_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HET1348414.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            complement(82254..83087)
                     /gene="rplB"
                     /locus_tag="VQO19_000092"
     CDS             complement(82254..83087)
                     /gene="rplB"
                     /locus_tag="VQO19_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HET1348415.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(83105..83401)
                     /locus_tag="VQO19_000093"
     CDS             complement(83105..83401)
                     /locus_tag="VQO19_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HET1348416.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(83401..84024)
                     /gene="rplD"
                     /locus_tag="VQO19_000094"
     CDS             complement(83401..84024)
                     /gene="rplD"
                     /locus_tag="VQO19_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HET1348417.1"
                     /translation="MANVTLFDQTGKEAGQVVLNDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            complement(84049..84675)
                     /gene="rplC"
                     /locus_tag="VQO19_000095"
     CDS             complement(84049..84675)
                     /gene="rplC"
                     /locus_tag="VQO19_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HET1348418.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            complement(84892..85200)
                     /gene="rpsJ"
                     /locus_tag="VQO19_000096"
     CDS             complement(84892..85200)
                     /gene="rpsJ"
                     /locus_tag="VQO19_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HET1348419.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(85466..86083)
                     /locus_tag="VQO19_000097"
     CDS             complement(85466..86083)
                     /locus_tag="VQO19_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HET1348420.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGVKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            complement(86080..86670)
                     /gene="nrdG"
                     /locus_tag="VQO19_000098"
     CDS             complement(86080..86670)
                     /gene="nrdG"
                     /locus_tag="VQO19_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HET1348421.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            complement(86663..87169)
                     /locus_tag="VQO19_000099"
     CDS             complement(86663..87169)
                     /locus_tag="VQO19_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET1348422.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDVEDFSYEEWL
                     EGNRNKEMGIWLPENRVPSIQFVLFGESGCALGFLNLRLRLNEGLLNYAGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            complement(87213..87353)
                     /locus_tag="VQO19_000100"
     CDS             complement(87213..87353)
                     /locus_tag="VQO19_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348423.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            complement(87365..89572)
                     /gene="nrdD"
                     /locus_tag="VQO19_000101"
     CDS             complement(87365..89572)
                     /gene="nrdD"
                     /locus_tag="VQO19_000101"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HET1348424.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKCLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKQEDYAWK
                     KAQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            complement(89692..91230)
                     /locus_tag="VQO19_000102"
     CDS             complement(89692..91230)
                     /locus_tag="VQO19_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET1348425.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            complement(91267..91410)
                     /locus_tag="VQO19_000103"
     CDS             complement(91267..91410)
                     /locus_tag="VQO19_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348426.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            complement(91488..93020)
                     /gene="cls"
                     /locus_tag="VQO19_000104"
     CDS             complement(91488..93020)
                     /gene="cls"
                     /locus_tag="VQO19_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HET1348427.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            complement(93166..93708)
                     /locus_tag="VQO19_000105"
     CDS             complement(93166..93708)
                     /locus_tag="VQO19_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HET1348428.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            complement(93705..94955)
                     /locus_tag="VQO19_000106"
     CDS             complement(93705..94955)
                     /locus_tag="VQO19_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET1348429.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLICQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KTLEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            complement(95265..95570)
                     /locus_tag="VQO19_000107"
     CDS             complement(95265..95570)
                     /locus_tag="VQO19_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HET1348430.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            complement(95586..96005)
                     /gene="ruvX"
                     /locus_tag="VQO19_000108"
     CDS             complement(95586..96005)
                     /gene="ruvX"
                     /locus_tag="VQO19_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HET1348431.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            complement(96009..96275)
                     /locus_tag="VQO19_000109"
     CDS             complement(96009..96275)
                     /locus_tag="VQO19_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HET1348432.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            complement(96362..96931)
                     /locus_tag="VQO19_000110"
     CDS             complement(96362..96931)
                     /locus_tag="VQO19_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET1348433.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            complement(96997..97395)
                     /gene="spx"
                     /locus_tag="VQO19_000111"
     CDS             complement(96997..97395)
                     /gene="spx"
                     /locus_tag="VQO19_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HET1348434.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            complement(97527..98588)
                     /locus_tag="VQO19_000112"
     CDS             complement(97527..98588)
                     /locus_tag="VQO19_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET1348435.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            complement(98581..101412)
                     /gene="uvrA"
                     /locus_tag="VQO19_000113"
     CDS             complement(98581..101412)
                     /gene="uvrA"
                     /locus_tag="VQO19_000113"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HET1348436.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            complement(101901..102320)
                     /locus_tag="VQO19_000114"
     CDS             complement(101901..102320)
                     /locus_tag="VQO19_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HET1348437.1"
                     /translation="MTPEQVKEKLEGVKWINKEIKGLYLELETLEGGIIKKPTLSHSR
                     VQTSRENKTENNLISVLKLKEDTLQRIERLTEERMKISELIDKLANPLERSVLRLFYL
                     NDLVVSEVAEEIDRSNTTVYIIRQKAIEHLTGIVNGD"
     gene            complement(103527..104036)
                     /locus_tag="VQO19_000115"
     CDS             complement(103527..104036)
                     /locus_tag="VQO19_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000811078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348438.1"
                     /translation="MKQLAIEAITKPMKLRGISKGIAELDGQRLEIDLDSLMIDFGGE
                     SFELDRIAGTKGGNRYFFLCPDCGRRCRLLYKRYLYFSCGTCLDIHKHTLNRSKTDCQ
                     YYWELALKEARKVEPGWSPRRGGYMFDSFPERPKYMKQKRYYKHYQKFINYTRKGDSF
                     WLNGLSSLR"
     gene            complement(104107..104637)
                     /locus_tag="VQO19_000116"
     CDS             complement(104107..104637)
                     /locus_tag="VQO19_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348439.1"
                     /translation="MTLKTFSSKAKTFTFTYEFKDLDTALVAGHALLGYMTGTYCQPV
                     ISLTYKDKGTLVAEYVEDHKLNKTFKRICDSFKDYHKQPGEAEAFEERYKRERVLQLK
                     ESEDFESLLNKVTDYELELLDYADRLLSDKPIPMDSMTAFATLEMLGDESISLLQKLD
                     VEGEYKGLAGYTEHLK"
     gene            complement(104721..104888)
                     /locus_tag="VQO19_000117"
     CDS             complement(104721..104888)
                     /locus_tag="VQO19_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348440.1"
                     /translation="MKVKLFEYTRRWEKEDFEKEIDDFMATVEVLDVKFSGTPSSESF
                     NSVAIVLVLYR"
     gene            complement(105249..106718)
                     /locus_tag="VQO19_000118"
     CDS             complement(105249..106718)
                     /locus_tag="VQO19_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase family protein"
                     /protein_id="HET1348441.1"
                     /translation="MEQEHPPRTMKELENRIFKAGEEWRAEHTETKVNENTGDVTEKV
                     AMPQTFTVAKILSEIVTFTFISKSNIPDYSLLYIYDLDEGIYTASNDLFNLLCKTFDV
                     RIKPREWPQIKLMVRTLAKIRKPLESANLIPVQNGIINLETKELLPFSPKYVITSKIS
                     TAYHAPKRVPTDREGKTFDDWLNSIACNDSELVTLFWQIILEAINPNHTRNKFAIFYG
                     DGNNGKGTFQRFLINLIGESNISALKPAQFAEKHNLETLVGKVCNIGDEAPNEYLKNP
                     SDLMSITSGDTVLVNPKGRPAFEATFKLFNIFSGNYIPNGGNKTKGWYRRIMIVPFNA
                     DFNGEKEKPWIKNEFLANKEVLEYALYKAINQEPFTHFIEPKAVKGLLEEYQEDNDYL
                     LSWVKHEYMEKGWHELDVVPVFIVTRSLKHYAEDMGIPKPNVYGAGKETIKHLQQLTP
                     NRYSLRKKRVSPEDFEKLEAWDVDKIKMRTPQHSITKQE"
     gene            complement(106771..107637)
                     /locus_tag="VQO19_000119"
     CDS             complement(106771..107637)
                     /locus_tag="VQO19_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HET1348442.1"
                     /translation="MTIYEAKGFQSNLVYPFDKIEPFQYIERFKPLVVPEGADIEEYK
                     RTQAPYCISGKVTPEKHGSYKRNNSSLIYRDLIFLDYDDIQGTSEGFIKAISSALFGY
                     SYILYPTIKHSLEKPRFRLVVKPDNVMNEATYKQVVKEIADKIGLPFDMASLTWSQLQ
                     GLPVTTGDPASYQKIVEHGLDYPVPQTTAEPVKQNAASLPYTPRPSGQKSMTMRIIDT
                     LFNGFGDEGGRNVALTRFVGLLFNKWVDCDLETAYELTKIANSVTVEPLPIEELDRTF
                     SSIARAEYRKRG"
     gene            complement(107772..108053)
                     /locus_tag="VQO19_000120"
     CDS             complement(107772..108053)
                     /locus_tag="VQO19_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET1348443.1"
                     /translation="MFSLSRESEQDLAHGILEVVERYLEARDTVKPRLTGLISAQEVM
                     DELDIKYMTLQKWEKAGLRRYQPPLEDTRKIYYKISDIWKFLGVENGKV"
     gene            complement(108046..108387)
                     /locus_tag="VQO19_000121"
     CDS             complement(108046..108387)
                     /locus_tag="VQO19_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET1348444.1"
                     /translation="MSLSENDKRVLRLIKVGAENSITGAEISLITKLAERTVQDIISR
                     LITRHSVPIVGVRHGTFRGYFIPANKEELLDGAKAFYNQVQEEQKRLTVLLNADLESY
                     KETLKEVGGYV"
     gene            complement(108384..108599)
                     /locus_tag="VQO19_000122"
     CDS             complement(108384..108599)
                     /locus_tag="VQO19_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348445.1"
                     /translation="MNELDLTNTQSVIFMVVLIGLLLYLNHRDRKKSAQFERENQQRI
                     ETPSEDLSPDYGRYIQLAGVRVYGGTE"
     gene            complement(108601..108801)
                     /locus_tag="VQO19_000123"
     CDS             complement(108601..108801)
                     /locus_tag="VQO19_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348446.1"
                     /translation="MTLNLDNMTQAEFDEVMAEIKEKRPNLFQFIADFVDRKVSTEEV
                     DEYLKMKHEKQVEFIKNYQARA"
     gene            complement(108798..109250)
                     /locus_tag="VQO19_000124"
     CDS             complement(108798..109250)
                     /locus_tag="VQO19_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348447.1"
                     /translation="MTETTYENLTRHIDRISAEMREIGEKNGLSRLSLLANQTKFIKE
                     NLHRLLWIELPELNDSHKIEAVSKSTTGMFFHAGIFEMDAMRQAFFKRQAMHFFDNEA
                     EQQAYIEHAEKEYLEATITLKDILFNSKNGTQRVNKSCLIEKFEEAMQ"
     gene            complement(109622..110248)
                     /locus_tag="VQO19_000125"
     CDS             complement(109622..110248)
                     /locus_tag="VQO19_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HET1348448.1"
                     /translation="MELVYMDGKKEPYTLSSIVAECAEVKHRHLKILLNKHREDFESF
                     GKVQFKISPSESGQNVRDYILNEQQATLLITYLRNTEPVKEFKKNLVKAFFEMREELS
                     KFRMQRALEKPKRKTLHDSIETWEAKPKHAHSTMNNLLLKAVTDMNAKQLREERGGYN
                     GIDSLTSDELEQYQAFEDMVIAMIGLNMSYQEIKAMAFRNKKTRQRSA"
     gene            complement(110264..110493)
                     /locus_tag="VQO19_000126"
                     /pseudo
     CDS             complement(110264..110493)
                     /locus_tag="VQO19_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            110646..111359
                     /locus_tag="VQO19_000127"
     CDS             110646..111359
                     /locus_tag="VQO19_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET1348449.1"
                     /translation="MAKNSPQDLKNREYFSNNLNRVMKEKGIRQIDLHNALEIPKSTI
                     TGYVKGRSMPTSGNLQKLADYLGVKKSDLDPRFSDKDVYKEFLYMLDKQLDEEKYLVK
                     NVSKDKIFQKVKEREKRDKEIIELAKSKNFPISPEEFLTTITESLNEYNPKDNYEVLN
                     ALALKTSNILFWLDIVFQKTSSEFYIVFEDKEFNQEYYNKLYKKFENLFEEIKSLALQ
                     EAKKDKENLDDFALLWGID"
     gene            111532..113046
                     /locus_tag="VQO19_000128"
     CDS             111532..113046
                     /locus_tag="VQO19_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HET1348450.1"
                     /translation="MRKYDIPKLLLSGENQGVEFKEAKNSFPKDGMKTICSFANTNNG
                     LLILGVSENTKNKDFYISGVNDPDKVLDELYSLLNNPNKINRNVINEESVEVVNIKGK
                     EIVIIPVNKVDYKDKPIYLNDNIASTYFRQGTGDFRCSQEQINSMLRDSAKESFDSTL
                     IQDFSILDLDTETIKLYREKFDNINAEHPFSKLDNEQFLIKINALRRDRKDDKIKPTV
                     AGLLIFGTHNSIKEFIPHYNVEYVLKEFSENNRFKDRVIYDGTWGEDNLFNFFYLVIE
                     KLYLTLNDNSNIQENSMNRIGISKLRIAIREAFINSLIHSDYKSEKGIMIIRYPDRYI
                     FTNGGTLRIDIKDFFSGAHSDPRNYLIQEIFRFLNLCEKAGTGIPKIMEAVKESHLKY
                     PNLRTELDSVEFTLWDTSLIDNLDIDNEYEKKILELIIEHRFVTREALEEKLKIHKNT
                     ILKYLKKLVEKQAIDKFKSGRQYVYFITQNQDPEFQKYNHINAMYSLLEEIKRK"
     gene            113131..114297
                     /locus_tag="VQO19_000129"
     CDS             113131..114297
                     /locus_tag="VQO19_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET1348451.1"
                     /translation="MKITEVIKKDGSKVYRANVYLGVDQVTGKKVKTKVTGRTQKEVK
                     QKANQEKIAFQKAGSTRQKAVTIKNYQELATLWLESYKNTVKPNTQGNVKKLIDNHIL
                     PIFGAYKLDKLTTPLIQSIINELADKTNRGEKAAFLHYDKIHALNKRILQYGVTMQAI
                     PSNPARDVVLPRNTQKAKRKKVKHFENQELKKFLGYLDNLDTHRYRYYYETTLYKFLL
                     ATGCRINEALALSWSDIDLDNAVVHITKTLNRDIEINSPKSKASYRDIDIDQATVSML
                     KQYKLRQTKEAWKIGQRERVVFSDFIHEYPSSSRLKRRLQTHFKRADVPNIGFHGFRH
                     THASLLLNSGIPYKELQYRLGHSTLSMTMDIYSHLSKENAKKAVSFYETALKAL"
     gene            114451..115395
                     /locus_tag="VQO19_000130"
     CDS             114451..115395
                     /locus_tag="VQO19_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET1348452.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            115407..116090
                     /locus_tag="VQO19_000131"
     CDS             115407..116090
                     /locus_tag="VQO19_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HET1348453.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            116345..117379
                     /locus_tag="VQO19_000132"
     CDS             116345..117379
                     /locus_tag="VQO19_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HET1348454.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKVLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALETPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAYVDAQE
                     QVIRFDYNKK"
     gene            117485..117748
                     /locus_tag="VQO19_000133"
     CDS             117485..117748
                     /locus_tag="VQO19_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348455.1"
                     /translation="MTKQKINRIVGSIGAFIGIIVFIAYIPQIIANLQGNKAQPFQPL
                     SAAISCLIWVIYGWTKEPKKDWILIIPNSAGVILGGITFLTSL"
     gene            complement(117833..118264)
                     /locus_tag="VQO19_000134"
                     /pseudo
     CDS             complement(117833..118264)
                     /locus_tag="VQO19_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166574.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
     gene            118814..118984
                     /locus_tag="VQO19_000135"
     CDS             118814..118984
                     /locus_tag="VQO19_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HET1348456.1"
                     /translation="MKYFEVELENPDEFLKLQTEDFVKANRLLLRKIIQSVTVYEENF
                     VISFKSGIELEV"
     gene            119370..120587
                     /gene="mef(A)"
                     /locus_tag="VQO19_000136"
     CDS             119370..120587
                     /gene="mef(A)"
                     /locus_tag="VQO19_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012102963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide efflux MFS transporter Mef(A)"
                     /protein_id="HET1348457.1"
                     /translation="MEKYNNWKRKFYAIWAGQAVSLITSAILQMAIIFYLTEKTGSAM
                     VLSMASLVGFLPYAILGPAIGVLVDRHDRKKIMIGADLIIAAAGAVLAIVAFCMELPV
                     WMIMIVLFIRSIGTAFHTPALNAVTPLLVPEEQLTKCAGYSQSLQSISYIVSPAVAAL
                     LYSVWDLNAIIAIDVLGAVIASITVAIVRIPKLGNQVQSLEPNFIREMKEGVVVLRQN
                     KGLFALLLLGTLYTFVYMPINALFPLISMEHFNGTPVHISITEISFAFGMLAGGLLLG
                     RLGGFEKHVLLITSSFFIMGTSLAVSGILPPNGFVIFVVCCAIMGLSVPFYSGVQTAL
                     FQEKIKPEYLGRVFSLIGSIMSLAMPIGLILSGFFADKIGVNHWFLLSGILIIGIAIV
                     CQMITEVRKLDLK"
     gene            120608..122071
                     /gene="msr(D)"
                     /locus_tag="VQO19_000137"
     CDS             120608..122071
                     /gene="msr(D)"
                     /locus_tag="VQO19_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(D)"
                     /protein_id="HET1348458.1"
                     /translation="MELILKAKDIRVEFKGRDVLDINELEVYDYDRIGLVGANGAGKS
                     TLLRVLLGELTPPGCKMNRLGELAYIPQLDEVTLQEEKDFALVGKLGVEQLNIQTMSG
                     GEETRLKIAQALSAQVHGILADEPTSHLDREGIDFLIGQLKYFTGALLVISHDRYFLD
                     EIVDKIWELKDGKITEYWGNYSDYLRQKEEERKSQAAEYEQFIAERARLERAAEEKRK
                     QARKIEQKAKGSSKKKSTEDGGRLAHQKSIGSKEKKMYNAAKTLEHRIAALGKVEAPE
                     GIRRIRFRQSKALELHNPYPIVGAEINKVFGDKALFENASFQIPLGAKVALTGGNGIG
                     KTTLIQMILNHEEGISISPKAKIGYFAQNGYKYNSNQNVMEFMQKDCDYNISEIRSVL
                     ASMGFKQNDIGKSLSVLSGGEIIKLLLAKMLMGRYNILIMDEPSNFLDIPSLEALEIL
                     MKEYTGTIVFITHDKRLLENVADVVYEIRDKKINLKH"
     gene            complement(122189..122488)
                     /locus_tag="VQO19_000138"
     CDS             complement(122189..122488)
                     /locus_tag="VQO19_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348459.1"
                     /translation="MNQLEFQRNHLQMDYYSESYQDFERDFYRYSNMNIPLTFLTDDI
                     LKTMATSRKNYFVLNKEKSRDNRDHFFIFEVSTVDENPLIYHYTYKKTTIYLAEK"
     gene            complement(122475..122843)
                     /locus_tag="VQO19_000139"
     CDS             complement(122475..122843)
                     /locus_tag="VQO19_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348460.1"
                     /translation="MIDRSYLPFQSAREYQDTKMQKWMGFFLSEHASALSDDTNKVTY
                     MSDLSLEKKLLLLSQVYAGQLRTRIQVIEKNKRVSYTGTIPSLTKDFILIKTTTGHIN
                     LKLKDIISIELVEEVLYESA"
     gene            complement(122856..123191)
                     /locus_tag="VQO19_000140"
     CDS             complement(122856..123191)
                     /locus_tag="VQO19_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imsC-like protein"
                     /protein_id="HET1348461.1"
                     /translation="MKQEKNTVQFSEIRSKGCNDIEMLERFLHGIVETATSKLRQRKL
                     KTTEISIRLVHAKSENRLPLEFTFSIKPTSSSVIIYTEVINRFKECYTGGGIQGFTIQ
                     FDKNTLASA"
     gene            complement(123188..123433)
                     /locus_tag="VQO19_000141"
     CDS             complement(123188..123433)
                     /locus_tag="VQO19_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348462.1"
                     /translation="MRQIGVSYSGFVDESYTLLSLFDDVEQIEKDNRLQTAIDVVREQ
                     FGFLAIQKGTVLTEGSRNIERSKLIGGHSAGGLEGLK"
     gene            complement(123615..123806)
                     /locus_tag="VQO19_000142"
     CDS             complement(123615..123806)
                     /locus_tag="VQO19_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HET1348463.1"
                     /translation="MTKRCSWVKVTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     VLRAFFYTNRRKGVKMIFK"
     gene            complement(123816..124409)
                     /gene="ruvA"
                     /locus_tag="VQO19_000143"
     CDS             complement(123816..124409)
                     /gene="ruvA"
                     /locus_tag="VQO19_000143"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HET1348464.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     regulatory      124566..124680
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            124814..125914
                     /gene="ribD"
                     /locus_tag="VQO19_000144"
     CDS             124814..125914
                     /gene="ribD"
                     /locus_tag="VQO19_000144"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HET1348465.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAIIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRKSPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHYVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     gene            125899..126534
                     /gene="ribE"
                     /locus_tag="VQO19_000145"
     CDS             125899..126534
                     /gene="ribE"
                     /locus_tag="VQO19_000145"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HET1348466.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSQQVGNTVNLENDILGKYVQKLMDNSPKLEISKELLYQNGF"
     gene            126554..127759
                     /locus_tag="VQO19_000146"
     CDS             126554..127759
                     /locus_tag="VQO19_000146"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HET1348467.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            127760..128227
                     /locus_tag="VQO19_000147"
     CDS             127760..128227
                     /locus_tag="VQO19_000147"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HET1348468.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(128552..130501)
                     /gene="mutL"
                     /locus_tag="VQO19_000148"
     CDS             complement(128552..130501)
                     /gene="mutL"
                     /locus_tag="VQO19_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HET1348469.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     KVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            130857..131297
                     /locus_tag="VQO19_000149"
     CDS             130857..131297
                     /locus_tag="VQO19_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET1348470.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            131294..131752
                     /locus_tag="VQO19_000150"
     CDS             131294..131752
                     /locus_tag="VQO19_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HET1348471.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            132062..133324
                     /locus_tag="VQO19_000151"
     CDS             132062..133324
                     /locus_tag="VQO19_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HET1348472.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
BASE COUNT        39789 a        28718 c        24445 g        40629 t
ORIGIN      
        1 ataatcgtat tgattaacgt tttgaggcaa ctgaccttgt caggttgcag ccacatttgt
       61 aagcgactaa agtcgcaaca actgtgtcaa ttacaccaat ttagtaagaa agtataaaaa
      121 aagaacaccc cgaaaggtgc tctgtataag tatagtaatt ctttcgaatt aacgcttact
      181 aaattgtgat gctttacgag ctttcttaag acctggtttg gctaacctaa taactaagtt
      241 ctttcaatta cctttaatca aaccattttt aactaccaaa tatttactag ttctcaacta
      301 atttcaacca ttttcatcta aatagggcaa atttttctac aaaaccaacc aaaacgagtc
      361 agctttatca gtaatttgcc ctaaatgatg aaattttatt attaaattca ttgaatattt
      421 ttttcttgat aactatttat tatgtcttta ataatatgtc ttggtaattt actgtaataa
      481 ccatctaaca ttttcttcaa aatttcttct tttaacattt tttttacatc aggattctct
      541 agcagggata tgagttcaag cggttcaact tcatcaatat caatgctagc taacctattt
      601 tctgaatcaa tataatatac aacactcgag ttatttgact catttcttgc tcgcacatct
      661 ttttctgctt tatctaaaat ccattttgga aacgtaacaa catacttctt ttcttcctgg
      721 gcctctatcc tatcaatttc atcttctgat aactctgtaa tcatgtttac gagtgtagta
      781 ttgtttaata tatataattt ttttctacta cacatatata attcattcat caagaaaata
      841 cttggaccaa ctttcatatt tgaagtttta taaattaaat cacttttttt atttgattct
      901 ccgtcattag taataaagat aactttatca ccacgaggtt gttccgttgc tttttttaat
      961 atatccttcc aaataattaa atcaccatat ttttgatgat aagatatgcc attatatttt
     1021 cttattccat ctttattttc gtcattaaat cccggtggaa tagcttctgc aaaacgtttt
     1081 tctccttctt tttctatttc atatatccat tcctgctcat acacatctcc aatagaatca
     1141 gaaataatat taagtaactc tttataaact tcatcttctt tatcagtaat ttcatctctt
     1201 acaaataaat tcaccttagc caaaaaatca tcagtaaaaa actccaaatt cccaatcaaa
     1261 tgttttagtt taccattctc aatatccatt ttaattaaat cagtattctg tacacttgat
     1321 tttaattgat tcaatgcaga ttcaacttgt ttaaagtatg agtctgcatt tctcttttta
     1381 gttttctttt tattactttt attaaaatga aattcaagag cgactaaata aggtatataa
     1441 agatttctct ttattgattt taatgaatcc acatacttag tagctatatc aattggcaac
     1501 tctaaaatct gtaataaaaa atttgtatca actacaatta aattattttc atcttttata
     1561 tcagttgttt ctaatttctc ttggtgaaat tctgggaaca tttcaattac ttttttcata
     1621 tatatattta cctcaattac ttatatagtt cattataaca aatattctga aatttaacgc
     1681 tatgaaattt aaatatagcc ataacttaca atccacaaaa aaatatttga aaaaattttt
     1741 ttctaaatct cttgcatttt ctgaaaaaat agttataata aaagtatagt tgttttacaa
     1801 caaaatagaa taggtagaat tatggataac acaaaagtta ttgaatggtt aaattactgt
     1861 gaccaaaacg atatcaaacc atggttatgg gattttaaaa attgttactc tagcgagtta
     1921 accgcagata atatttcaaa ttttctaaaa tataaaaatg gagaactcgt aaatccttcc
     1981 acattttgta tcacaaaaca ggttggtagt aacgctgact gcgataaaga ggcactccca
     2041 ctttataatg ttttaggttg gcaacattcc gagagagata taataagagg tgagacctta
     2101 aattcttata taactacatt tactcaagct attaccaatg acccgaatta taaagaaatt
     2161 tgtaaaaaga ttggagtaaa cttaaatgaa tatctaaaca agcagtatcc aatcttacac
     2221 cataataaaa actatcaaaa tttcaagatg attcaaaaaa acctaaaaga atttgaagca
     2281 ttcgcaaaat taacacatac aatcggaaac tttactgtat tgcctcattg gatgaatact
     2341 ggacgataca atttctcaaa agattactgg gatattacaa tgctttctct tcaagaatgg
     2401 cttactaatt tatctcctca agcatggaaa aattttattg atacatacta tcttcaaccc
     2461 tatgttgata ataactatca aacagaggta ttttgggaaa ctcataacta cgaatacatt
     2521 tatcccaaga aaaccgaaga tttctccatc ttcctaaaaa gagtcaatga acggattgag
     2581 gagcgcggga aattcatcat taaacaaata tgcgataaac taaataaaaa agatttccat
     2641 ttctataagg aaattgaaaa tatggataaa attaaatact caaatgaatt tgaacaagag
     2701 aggaaacaat gactagagta tataaaagcg tccgccttgc gtacgaggca aaggtatgga
     2761 tagatgaatt gattcaagaa aaagaacgta aaattcaaga acttaataaa gaggattttc
     2821 tagataaact tgaaaaaaca cttcttaaaa atcactatga tgaattgaat ggtctttcat
     2881 ttaatatcat tctaaaagcc tcaataggga gtgtcataga agaatcctat cgaaatacta
     2941 aacactatcc aattgacaaa tggcaaaagc tacgtcagca gatggaaagg gacgtaaaaa
     3001 atgttaatcc taacttagaa accacagtta ctccccgtat ttatctagac gaggatgtgc
     3061 ttgctgggct tgatgatttt cgctatgttt tgatgaaaga ggactgtgct actagactac
     3121 ctcgtcttag ctacattatc aaacttgttg tatattccta ctggaaagaa caacactaat
     3181 ctaatcagtt ctactgttta gattttcatt tctttaaaat gtatatttgt tgtactacta
     3241 ataaatctag aaaaataggt aatctatgtt taaattaaag aaagtcgctg acttaaaaag
     3301 aaattatatc atttcaacta acaaattaaa ggtaactcat tggtcaatat taagcctctc
     3361 tatctgcatt atgcttacta ttattgcaaa tattagagcc cctgacctta ttaaaatccc
     3421 tttacttatt ctagtaggat ttgtcatata caaatttcat cgtcaattaa aatattttag
     3481 atataattta gattattacc taattatcag agaaagctta ttgtatgtat tacatacaaa
     3541 ccgcctttat acaacacata aagatagctc aggatatgaa aaaatctcta ggagcgcaat
     3601 cttacaatac gagttagaca aacaaaaggg gcatatcttt atcaaagctc tgattactgg
     3661 tgatgaattt agtaaaaggg tacaatcact tgatgatgtt cttgctggag tactcgaact
     3721 ggaactagaa tacaaaatta ttcgtcctag ttttatggaa taccatttct attacaagaa
     3781 acctgacagg ttagttcttc aatctcacaa ccagaagcaa gagatagata accttaatat
     3841 agatttagga tacggtgtga attataatcc tatcaagtgt cctcatattc tagttgccgg
     3901 aggtacagga agcgggaaat cagtatttat atctttaagg aaatcacttt gttaaacgct
     3961 ataaaacaag aaaggaggct aaagaagctg aattagaaat tctaacaaag atacatcaac
     4021 ttgaaaatgg agaggatatc ccactcctta aaactagtga tattcttttc tctgagttct
     4081 ttaataatat ttggtgggat tcatacaaag ctggtcaaac aacttcaaca actaaacccc
     4141 caacacaagt tactattgat aatactgaaa tagttttcag gaagcacatc ttaccaatgt
     4201 tcggtaatta ttcaatcaat tttctgaatc agaataagca aatcgtacta aacttaatga
     4261 ctgctaaagc tgaagaatat gctaatttca aggttattcg aagctatgta aactcaattt
     4321 tcgattgggc tgaagaatta gaatacattg aatcaaatag attatcaaaa agcataaaac
     4381 gtattaaagc aagtaaaaaa ataaagctag aagaagctaa ggatgaggaa gatttgtatc
     4441 tatctagtga agaattacaa gattggtttg atgcttttag agaagatttg gagaacgaca
     4501 aattatcact aaaagattat gtcctattct ttacaacctt tattttgagc gatagaaaat
     4561 cagaatccta tgctctacat tggaaaaaca tagacttggc aaacgctcaa attggcttaa
     4621 ggcatgcact tgacaaatat aagaatgtaa agtcaacaaa aggaaataag aaaacgattt
     4681 tttcaattcc tagttacctt gtatcacttc tttcagaatg gaaaaaacag cagaaatatg
     4741 agttagcgaa atttggtata atgcaaacat ccgatcaact agtctttacc tatatagata
     4801 cgaaaggtaa tgtaaatagc cctctacacg ttgattatct caataacaaa atgaactctg
     4861 taaaaagacg acacccaaag ttaaaacacg ctacacctca taaattacga catacaggag
     4921 cgacacttgc taaaaaggca ggaatgagct tagaagccat ttctgaagta ttaactcata
     4981 gtgatacaat tacaactaaa acttatgtta atgcttcaaa catagttcca ttatctgctg
     5041 gacaagttgc ctaccaacat cttaaaaaca agtagggtaa ttttagggca aattttaggg
     5101 aaaacttttt tagaaagtat agaaaaaagc acccataggg caaacctttg agtgctttga
     5161 aacattgata taatcgtatt gattaacgtt ttgaggcaac tgaccttgtc aggttgcagc
     5221 cacatttgta agcgactaaa gtcgcaacaa ctgtgtcaat tgcaccaatt tagtaagaaa
     5281 gtataaaaaa agaacacccc gaaaggtgct ctgtataagt atagtaattc tttcgaatta
     5341 acgtttacta aattgtgatg ctttacgagc tttcttaaga cctggtttct tacgttcaac
     5401 tttacgtgag tcacgtgtaa gaagtcctgc gcgtttcaat gaatcgcgga agtctgggtc
     5461 tacttgaaga agggcacgag cgataccgtg acggatagct cctgattgac cagcgtatcc
     5521 accacctaca acgttaacga aaacgtcgta tgaacctaca gttgaagtaa ctgcgaatgg
     5581 ttggttgatg acaagacgaa ggtcagcgtg tgggatatac tcttcaacat cttttttgtt
     5641 aacagtgatt ttaccagttc ctggaacaag gcgaacgcgt gcaacagcgt ttttacgacg
     5701 tccagtacct gcatattgtg cttgtgacat actttatttg ttcctttcct tagataagtc
     5761 ctgaaatgtc aagaacttct ggttgttgtg cagcatgagt gtgctcagct ccaacaaata
     5821 ctttcaactt cataccttga gcgcgtccaa gtgtattgtg tggaagcata cctttaactg
     5881 atttctcaat caaacgtact gcatttttag aacgaagttc acctgcagag atttgtttca
     5941 atccacctgg gtggtttgag tgagtgtagt agattttatc agttgctttt ttaccagtca
     6001 atttaacttt ttcagcattg ataacaatca cgaagtcacc tgtatcagtg tgtggtgtaa
     6061 atgttggttt gttttttccg cgaagtacgc tagcaactac tgcagaaaga cgtccaagtg
     6121 gtacatcagt tgcgtcaact acgtaccatt tacgttcaac ttggcctggt ttagccataa
     6181 atgttgtttt gttcatgatt tctcctatat atagttcgat ttttgtttac ggtgatgggt
     6241 gttccttccc atcgaaaagt atttggaagg ttccggggcc tttcaaatgg ggtaaacaat
     6301 accgcttact atcataccaa atttcacccc taaaagtcaa tagatataaa aaatattttt
     6361 cggtaacttc tcaaaataac tgaaagttat ataatcaagt taatttggga atttacctat
     6421 taacttcggt agatttttgg gaattttttc cctatttctc cctgtaacta aaatcctttt
     6481 caaaaaatca ccttttcttg atttttaatc ctatttgctg tatgataagg gaaaagaaag
     6541 gggacagaga tatggctttt accaataccc acatgcggtc tgctagtttt ggcattgtta
     6601 ccagcttgcc cgatgacatc attgactctt tttggtatat catcgatcat ttcttaaaaa
     6661 atgtctttga attggaagaa gaactcgagt ttcaattgct taataaccaa ggaaagatta
     6721 ccttccactt ttcaagtcaa cacctcccta cagccattga ttttgacttt aaccatcctt
     6781 tcgaccctcg ttatccccca agagtactgg ttttagacat ggacggtaga gaaactatcc
     6841 tcctcccaga agaaaatgac ctattttaaa aactctagcc ttcagttgca agtaactgaa
     6901 aactagagtt tttctatttt ttcaaagcat catacaagtt gcggatcggt tgttttaata
     6961 tcggatggat aaaatgaggc gcaatttcct gtaaggactc aaggacaaaa aggcgttccg
     7021 ctatgtaagg atgaggcaat atgaggtcgt ctgtataaag gatctggtcc tccacaaaga
     7081 gcaagtccaa atcaatcaaa cgaggtcccc aatgcacttc tctcacccgt cccagctctg
     7141 actcaatggc taacaaggtt tctaacaagt cttgtgctgg tagccaggtt tccacctcaa
     7201 ccacttgatt ggcaaagcta tcctgctcca ctccacccca aggctccgtc tctaagacac
     7261 tggactcttt gagaatatgg atgccacgag ctcgcagttt gtcaatggct tgcttcaagt
     7321 ttacttgttt atctcccata ttgcttccta gggcgataaa ggctcgttgc ttgcggcgat
     7381 gaatggttac cgagcaagta tctagtgaca aatgcaccgg tgcccaaggt tttttcagtt
     7441 ccaacttcat ttcttggaca agaggataag actcaaaggt acgttccacc agtttatagg
     7501 ctaccgtttc aatcaaatct tcactcgttt cctgaaacca agtcgtccac tgctgacaca
     7561 attctccgta atggacagag gctgttaaat ccaagtctgt agctgccttg gtcatatcat
     7621 aggataggat ggctgaaacg acaaatttct gccccaattc tttctcacta ggaaaaagac
     7681 catgataagc aaaaatttcc aaatccttaa tctgcagttg atccataagt agtcctttct
     7741 agaaaaatcc gcccaaagcg gattcttttt atactcaatg aaaatcaaag tgcaaactag
     7801 gaagctagcc acaggctgct caaaacactg ttttgaggtc gcagatggaa gctgacctgg
     7861 tttgaagaga ttttcgaaga gtattatagt cccattaaac gataagcctg atctcggagg
     7921 tccttatctg tttcaaatag accacgagct actgtcgtca aggttgcagt gcctggtttt
     7981 ctgacacctc gcatgctcat acacatatgt tccgcctcaa tgacaacaaa ggctccttta
     8041 gcacctagat actccatcaa ggcatcagcc acttcgatat tcaaacgttc ttgaatttgt
     8101 ggttttttcg aataaacttc aaccgtacgg gctagcttag acaaacctgc cacacgacca
     8161 tctggaatgt aggcaatatg tgctctacca taaaatggca agaagtggtg ttcacacatg
     8221 gtatggaaaa agatatcctt ttctactacc atattgtcat caataatctc aaaggatttt
     8281 gacaaatgtt cctccgctgt ttgaccaaga cctgaaaaaa tctcttggta catacgagcc
     8341 acacgagcag gtgtttcctg caagccctca cggttagcgt cctctcctac agcctcgata
     8401 atcattttta cagctgcttc aatcttttgt gtatccattt tcgttcttcc tctccatcag
     8461 ataggctctc acttggctca agaaatacaa ggaacccgtg acaatcctaa ctgtttgttt
     8521 ctcttctttt ttatctgtca atttctgctc tagaaaatcc tgccaacctt ggtagctgag
     8581 atttctagac ttggctgcct ctttcagcac gttttcatca gtcgcccgac tatcgtcaaa
     8641 atgtgtcagg gtaagctcgg tatctggcat ggcccccagc aagtccaaca tatcctccaa
     8701 ggccttggtt ttgatacaag taaagaggat ttccttacga taatccgcaa agcgttcttg
     8761 caaggttgct aataaagcct tgatagcatg ggaattgtgg gctccatcca aaatcatcaa
     8821 gggatctctt gacacgattt ccaaacgccc tggccaactt gtttcttcca aagcttgagc
     8881 aagcaagtga ttgcttgcta gttctcgacc atcttcttga caaaaagtat caagtaaagc
     8941 tatggccatc ccagcattct ctatctggtg caaaccaagc aggccagtct ggaagcgacc
     9001 ttgtctgaca acacttgtat agtcaaagac ttcgcctgta accacactct tttgatggct
     9061 gacctgataa tctgtcccgt agacaagtct cggcgcatct ttcccttccg caatgcggtc
     9121 aatcacagcc aaggcttctg gagcgatacg acctgtcacc aagggaattc cttgtttgat
     9181 aataccagct ttctgctctg ctatggcttc caaggtgtca ccaagtaggg ctacatggtc
     9241 cagtccaata gtcgtaatgc ctgttaaaat gggatggcag acattggtac tatccaaaag
     9301 tccacccatg ccgacttcca tgatagccac atctacttgc tctgaagcaa agtagtcata
     9361 ggctatagct gtaattatct caaattcagt tgtcccctgc aaattggcag ccgattcccc
     9421 ctcaagcaaa gactgatagt ccaccatgag agcttctagt ctagcctctg ggatagattc
     9481 cccattgatg ctaatctggt ctgtataatg aatgagatag ggcgagctaa acacgccaac
     9541 tctcagccct agcttttcca acatattttt caaaaaagca atggtcgaac ccttgccatt
     9601 ggttcctcca atatggatga ccttgagttt gagatgggga ttgccacgca acgctaacag
     9661 ttccaccatt cgttccaagc caaaatgcgg ttggtccgtc cggtagttag caatccactg
     9721 attgttttca atttctttca tcttatttat attgttttaa atctagattt tccgcttcat
     9781 cagccagacg aatagcggag gcaatttcaa ctgccatcct gtgactagct acgtcatgca
     9841 cgcgcaccac ttctacaccc tgtctcgcag cgatactagt tacatgagcc gaagctgtgt
     9901 cccgattgcg gaaaccaagt tctgtctcag gattgacttc aaaaccattt tcttcaagga
     9961 tattgatgac aaatcgctta cgcgacactc caagaaagat tggatagcct ttctgatgta
    10021 gtttatccag gtcccgtaaa agaagcagat tttctttctt ggtcaagcca aagccgattc
    10081 ctgggtccaa caggatattt tcttgtgtaa tcccagcttg atttgctctc gctagtgctc
    10141 gttcaaagaa agtctccatc aactcctcga ttggcaattt ttcaaagtca gctaactctt
    10201 cctctgtaaa agcttgacca aatccaaaat gagggaagat gagcgagcta ggatgctgag
    10261 gtcgcgccat gactggatta aacataatga ctactttcgc tccagcattt gcaaccacat
    10321 gggccatttt ttcatcaccc atgaaaccag tgatatcatt gactagattg gcaccagcag
    10381 ccaaagcagc ctctgccacc tgactcttcc aagtatcgat agaaataagg acatcacttt
    10441 ccttgcgaat cgctttgatc actggaacaa cacgctggat ttcctcttct atctcaacat
    10501 agctacttcc cggccgaggc cgagtcgatt ctccgccgat atctagcata ctagcccctt
    10561 ctgctatcaa tttacgagcc tgctggagtg cctgctcaag agcaaaaaat tgaccaccat
    10621 ccgaaaagga atctggggtt acattgataa ttccgcaaat agctgtcttt gcatgatttg
    10681 ctttagttga catatcggtc actccctcaa ggcttttcac catattattt ctctatttta
    10741 ccataaaaag aaaaaaatgg acacgattgc attcatcttt ttcccagtag aaacaagtaa
    10801 gcaattgtca aaaatcttaa acagagattc ctaatgtccg actcaaaatc accacgagag
    10861 ccaacaaaca gaaagcaacc ccattcacaa tcatgtgaag caagatcgac atttccaaac
    10921 gttgggtctt gtaggccgtc caagatagaa ctgtcgacat acctccataa atcaataaag
    10981 aaggtaaatt acttggttga tgcaataaag caaacacaat cgtaccgact acaaatccca
    11041 agttctcctt gcctcggaaa atctttttag gaacaatccc acggcacaag atttcctcac
    11101 aaatcggagc aagcaaggct agcaagaaga aactggaaat caacgaacta ttttgaacca
    11161 tatcgttaat ctgagactgg ttagctgttg tcgtctcatt tgacagttgc aacaagatag
    11221 aaccaagtat atttgacccg acaataacta aataactcaa gcccaaacgt gccaaatctt
    11281 tagctctaaa aaaagaaaaa ttaaaactag ctaacttggt tttacgagct cccataataa
    11341 atagagccag aaccacaatt gaaaggccag caactatcag ccctgactgt agcagggcta
    11401 cttcttttaa agtcaaaata gaggtaacca ctaggggaac ctgatataaa aggacggcaa
    11461 gtaaaaagac caaaatccag cctgcacgat tcaacaattc tttccacata tttttctctt
    11521 ttatcaccta tctcctttgt attaaaaaag gggggaaatc cccctgggtc attctattat
    11581 aaggccatgc tgatgtagtt aaggataaac aaggcatcca aaatccaaat catggcatga
    11641 acatctttaa cttgaccttt gacaagctta gtcaaagtgt aagtcaagaa accaactgca
    11701 atcccttgag tgatagagta gctgaatccc ataaagatag atgtgaagaa ggcaggaact
    11761 gcttcagaca tatcatccca atggatattt ttcaagctac caagcatcat aatcccaacg
    11821 ataatcaaga ttggagctgt agccgctgtt ggtacgatcg ctagaagcgg gctaaagaag
    11881 cttgaaatcg caaaacagat agctacaacc aaggctgtca aaccagtacg tccacctgca
    11941 ccgataccag cagcagactc aacataagtc gttacgtttg aagtacctgc aatggcaccg
    12001 actgtcgttc caatcaaatc agagtaaaga gccttatcca atttggctga ttggtgattt
    12061 tcaccatttg tcgctacaat accaactttt tcacctgtac cgatcaaggt accaattgtg
    12121 tcaaaaatat ctgtcaatga gaaggcaaga atggccatca gagtttcagg caagcgagct
    12181 gtatctgaaa ccaaagctcc caaaccttct gaaccaagag ctgcaccaaa gattgtcttc
    12241 aaatcttcaa aagctgcacc aacatggtta ttagcaaaat cgatactaga caaatcaacc
    12301 aaaccaactg caatagcaag aacagttgtt gtcaagatag agagaataat tcccccttta
    12361 atccctttga tgacaaagaa gatagtaatg gcaagtcctg caagagccac taaaacagct
    12421 ggattattaa agctgaccaa tcctggaact gctgaagagt ttgctgcaat cgttgcttga
    12481 gctttgtcag ccccttctcc tacaacagta tagttgcctg gatcaatcgt gaatttcaaa
    12541 agtccagcat tcttaatccc tacataggca aggaagacac cgataccagc tgaaatagct
    12601 gagcgaagag cattgggaat cgattcaatg atcattttac gaacatttgt caaggtaata
    12661 atcaatgaaa taatcccaca gatgaagacc atagctaggg cttcttgcca agaataacca
    12721 agcccgaata caactgtaaa ggtaaagaag gcattgagtc ccatacctgg cgcttgggca
    12781 taaggtaagt tagcataaaa agccatcatc aaggtacccg ctactgcacc aataatcgtc
    12841 gctaggaaga cgccctgagc aggcattcct gtttgtgaaa gtatttgtgg gtttacaaag
    12901 agaatatagc tcattgcaaa gaaagttgtt aaaccagcga gaacctctgt acgaacgtct
    12961 gtaccgttct cttttagttt aaataatttg tccatcatca atctcctttt aatttttacg
    13021 aacaataata gaattatatc atttatcatt cactttttca atgtctttgt ttgatttgtt
    13081 taagaaatta atccaatttc attttttgtt tggaatctgc ttttctgcct gctttctgtt
    13141 ataatagaag acatcttatc tgaaaacaca ctagaaaggt ccatatgacg aaaaaaatta
    13201 ttgcagttga cctggatgga accctgctca actcagacag tcaaatttct gactttacca
    13261 aaaaaaccat caaaaaagtt gctgaaaaag gccatcaggt tattattacg acaggtcgcc
    13321 cttaccgtat gtcaaaagat ttttaccgtg aactgggctt agacactcct atgattaact
    13381 tcaacggatc ccttactcat ttaccagacc aagtttggga ttttgaaaag tgtttgactg
    13441 tagacaaaaa atatctgcta gatatggttc aacgttcaga ggacattcaa gccgatttta
    13501 tcgctggaga atatcgtaaa aaattctaca ttacaaatcc caatgaagaa attgccaatc
    13561 ccaaactatt tggtgtagaa gctttccagc ctgaagatca attccagcct gaattggtga
    13621 ccaaggaccc taactgtatc ctcttgcaga ccagagccag tgacaaatat gccttggcaa
    13681 aagacatgaa cgccttctac cagcatcaac tttctatcaa tacctgggga ggtccgctca
    13741 atatccttga atgtacccca aaaggtgtca acaaggcctt tgctttggac tacttgctca
    13801 agataatgaa tcgtgacaaa aaagatttga ttgcctttgg agatgaacac aatgataccg
    13861 aaatgctcgc ttttgctggg aagggttatg ccatgaaaaa tgccaatcca gagctactcc
    13921 cttatgcaga tgagcaaatt tcccttacca acgaccaaga tggggttgcc aaaaccctac
    13981 aagacttatt cttataacct atactgatac tcaatgagaa tcaaagagca aactaggaag
    14041 ctagccgtag gttgctcaaa gcactgcttt gaggttgtag atgaagctga cgtggtttga
    14101 agagattttc gaagagtatg accagcttgc aagctggtct ttgtgctctt ttcacagtct
    14161 catcaaccag ttaatcgatt gttctacttt ttgtctccaa aaccttggaa aaggcttcct
    14221 tttgtgatat acttcacata taaatacaag agagctcgtc acactcgact ctgttgacaa
    14281 aaaatcaatc cagtcccgtt gtccctgttc tcggtcaata tcaaggagga tagctatgaa
    14341 agctgttgtt gtaaatccag aaagcactgg tgttgctatt gaagaaaaag tactccgtcc
    14401 acttgaaact ggggaagcac ttgtagaagt tgaatactgt ggcgtttgcc acaccgacct
    14461 ccacgttgct catggtgact ttggtcaagt cccaggacgt gttcttgggc acgaaggtat
    14521 cggtatcgtt aaagagattg ctccagatgt gaaaagcctt aaagtcggtg accgcgtcag
    14581 cgttgcttgg ttctttgaag gatgtggcac ttgcgaatac tgtacaactg gtcgcgaaac
    14641 cctttgccgt acagtgaaaa atgctggcta ctcagtagac ggtggtatgg ctgaacaatg
    14701 tatcgcaact gctgactatg ctgtcaaagt tcctgacgga cttgatccag cccaagcttc
    14761 ttctatcaca tgtgctggag taacaaccta taaagctatc aaagaagcaa aagttgaacc
    14821 aggccaatgg gttgttcttt acggtgctgg tggacttggt aacctcgctg ttcaatacgc
    14881 taaaaaagta ttcaatgctc atgttatcgc agtcgatatc aacaatgaca aacttaccct
    14941 tgcaaaagaa gtaggcgctg acattgtgat taacggcctc gaagttgaag atgtagctgg
    15001 actcattaaa gaaaaaactg atggaggagc tcattcagct gtcgtaactg ctgtgtctaa
    15061 agttgccttc aaccaggctg ttgactccat tcgtgctggt ggtcgcgtcg tcgctgttgg
    15121 tcttccttct gaaatgatgg aactcagcat cgttaaaaca gtcctcgatg gaatccaagt
    15181 catcggttct cttgtcggaa ctcgtaaaga cttagaagaa gccttccaat ttggtgcaga
    15241 aggtctggta gtcccagttg ttcaaaaacg tccagtagaa gatgctgttg ccattttcga
    15301 cgaaatggaa aaaggccaaa tccaaggacg tatggtactc gacttcaccc actaatttaa
    15361 tagaaaccta ttttaaaagt tggaagcttc ttccaacttt tttatattaa attttaaata
    15421 agaattcaag attactcctc aaaaactcaa catatcaaca tacaaaaata aaaatttttt
    15481 aattttttat gataaatagt tgcttttttt atgaaaacgg tttatactta aacagtctta
    15541 aagttttctt aaatgaaaac taaaacaaaa aaggaggaat gacaataatg agtatcggaa
    15601 tcattattgc gagccacggc gaatttgctg ctggtattca tcagtcagga tctatgatct
    15661 ttggtgaaca agaaaaggtt caagttgtga cctttatgcc aaatgaaggt cctgatgatc
    15721 tatacgctaa gtttaataac gctgttgctg catttgacgc agaagatgag gttctagttt
    15781 tggctgacct ttggagtggt tctccattta accaagctag tcgcgtgatg ggagaaaatc
    15841 ctgagcgtaa gtttgccatc atcacaggac ttaacttacc gatgttgatt caagcctaca
    15901 cagagcgcct catggacgct gctgcaggtg tagaaaaagt cgctgctaat atcattaaag
    15961 aagccaaaga tggcatcaaa gctcttccag aagagctaaa tccagttgaa gaagttgcaa
    16021 gcgctgcagc tgctccagtt gcccaaactg ctatcccaga aggaactgtt atcggagacg
    16081 gtaaattgaa aatcaatctt gcccgtcttg acacacgtct acttcacggt caggttgcaa
    16141 ctgcttggac tccagattca aaagcaaatc gtatcatcgt tgcttcagat aacgtggcta
    16201 aagacgacct tcgtaaagaa ttgattaaac aagcagctcc aggtaatgtc aaggctaacg
    16261 tggttccaat tcaaaaactg attgagattt caaaagaccc acgttttgga gaaacacatg
    16321 cccttatctt gtttgaaaca cctcaagatg cccttcgtgc catcgaaggc ggcgtgccaa
    16381 tcaagactct taacgttggt tctatggctc actcaacagg taaaacattg gtcaataccg
    16441 ttttgtctat ggacaaagaa gatgttgcta catttgaaaa aatgcgtgac ttgggtgttg
    16501 aatttgatgt ccgtaaagta ccaaatgatt ctaaaaaaga tttgtttgac ttgattaaca
    16561 aagccaatgt caaataagcc attatttatg aaaggatttt aaacatgtct attatttcta
    16621 tggttttagt aatcgttgta gccttctttg caggtcttga aggcatcctc gaccagttcc
    16681 aatttcacca accacttgta gcctgtaccc ttattgggct tgtaacaggt cacttggaag
    16741 cagggattat cctcggtgga tcgcttcaaa tgattgccct tggttggtca aatatcggtg
    16801 ctgctatcgc tcctgatgct gcacttgctt ctgtcgctgc tgccattatc atggttcttg
    16861 gtggtgactt taccaagact ggtatcggtg ttgcccaagc ggttgctatc cctcttgccg
    16921 tagctggact tttcttgaca atgattgttc gtacaatttc agttggtttg gttcatactg
    16981 cagatgctgc cgctaaaaaa ggtgacttcg gcgctgtgga gcgtgcgcat ttcattgcgc
    17041 tacttttcca aggacttcgt atcgcgcttc ctgcagctct tctccttatg gtaccaactg
    17101 aaactgtaca aagtatcctt agtgccatgc cagactggct caaagatggt atggctatcg
    17161 gtggtggtat ggtcgttgcc gttggttacg ccatggttat caacatgatg gcaactcgtg
    17221 aagtatggcc attcttcgct cttggtttcg ttctcgctgc tgtgtcagat attactctaa
    17281 tcggattcgg tgctatcggt gttgctatcg ctcttatcta ccttcacctt tctaaaactg
    17341 gtggaaatgg tggcggagga gccgcaactt ctaacgaccc aatcggcgat atcctagaag
    17401 actactaaga taagaaagga ctgaaaacat catgactgaa aaacttcaat taactaaatc
    17461 agatcgtaaa aaagtttggt ggcgttcaac cttcttacaa gggtcttgga actttgaacg
    17521 gatgcaaaac ttgggctggg cttatacact cattccagct atcaaaaaac tctatactaa
    17581 aaaagaagat caaatcgctg ctcttgagcg tcaccttgag ttcttcaaca ctcatccata
    17641 cgtagctgct ccagtcatgg gggttactct tgcgcttgaa gaagaacgtg ctaacggtgt
    17701 ggaaatcgat gacgctgcta tccaaggggt taaaatcggt atgatgggac ctcttgctgg
    17761 tatcggtgac ccagtattct ggtttacagt acgcccaatc cttggatctc tcggtgcttc
    17821 acttgccctt actggcaata tcttggggcc actcctcttc tttgttgcat ggaacttgat
    17881 tcgtatgtca ttcttgtggt atgttcaaga gattggatac aaggctggat cagaaatcac
    17941 taaagatatg tctggtggta tccttcaaga tatcactaaa ggagcttcta tccttgggat
    18001 gttcattctt gctgtccttg ttcaacgctg ggtaaatatt aaatttgctt tcgatgtttc
    18061 taaagttcaa ctagatgaaa aggcttatat ccattgggat aaattgccag aagggtctaa
    18121 aggtatccaa gaagcattcg cacaagtagg acaaggattg tctcaaactc ctgaaaaagt
    18181 tactactttc caacaaaact tggatatgtt gattcctgga ttatcaggac tactccttac
    18241 tttactttgc atgtacttac ttaagaaaaa agtatctcca atcactatta tccttgccct
    18301 cttcgcagtg ggtattgtgg cacatgttct tcacatcatg taatcaagca actaaaaagg
    18361 aaccaggttc taaaatctga ttcctttttt ctatgctttt atttagccaa ggctcccatt
    18421 ggatcccatg gtgcaagtac aattggttct gctccatagg cagcttgttc ttctgctgtc
    18481 agcaattcct tacgaacaac gatttggtat gtgtattcgt ccatccaagc gtctgaggca
    18541 acaaagtaac catctgtacc gaccttgtct ccccatgagt tttcaacctt ccacttggtt
    18601 gatttaccat tttcgtccaa gtcaacacct gtcaagacca tggcgtgggt catcaagctt
    18661 tcgctatagt ccaaacgtcc agccttgtct tgagtaagtt taatgtccat gcttgattca
    18721 aagtcataaa catctgtcgc aaggattcca gccttacggt tactgagctg gccgacatca
    18781 gaaccaaacc aaacagtctc acctgcttgc atttgggcaa tcgccaattc tttcaagcgc
    18841 tccattggaa cgttgatgta acgaactgca cggctaccaa ccacattccc caacatctca
    18901 actgtgtaag attttccgta aggtttatca gcagttggag cattgataac agaaacgtag
    18961 tcttctaaag gaagattgac atatttcttg tagaactctt gtggtgtgat tcctttttca
    19021 cttttgtagt tgttatcttt atcgcgataa gcaaagtcaa acttgcgtgg tggaagtcct
    19081 aatgacatag caagaaagtt aaagatttct tgcaagaggt cttctttctt agcttgaaca
    19141 gtcacttgat ctgcaccaga aacaagcaaa tcacgcaaga tttgagcatc ttgacgaagc
    19201 aatttattaa ggatcgcatt tagctcacga ctgctgctag atgaaacaga ctcaggataa
    19261 actgacttag gcacgacacc gtatttttca aagagggaaa cgaccatatc ccattgacca
    19321 ccatcttgtt gaggtgtttg gagtaagaag ctaaccttgc ggctagtcaa ttcttggtct
    19381 gaagtcgcaa tgacttgctc caagaaccag tttgatttct catacttatc ccagaagaaa
    19441 gtgtgggctt gtgacaactc aaagttctcc aatttgtatt gcgagatgag tttgtggcgg
    19501 aaggtgttga gagccgcaaa catccagcaa cgaccagacg ctttctggtt agtgaccttg
    19561 tccttggtta aatccaatga gaaaacaggt gtgttgtcta catggctttg gcgacgttcc
    19621 agagctgcaa aaattccgtt gtggctggca gcattttcaa tcgcttggta ttttacattt
    19681 gcttcatagt tggcaaatag tttatcagta aatgattctt gaatcgcgtt catagattcc
    19741 tccttttatt ctacagtcta ttataactct tttcacaaag gaagcaacta aaaaacataa
    19801 aaggtaagga cattctccct cacctttttc gaatttatac tcttcgaaaa tctcttcaaa
    19861 ccacgtcaac gtcgccttgc cgtactcaag tacagcctgc ggctagtttc ctagtttgct
    19921 ctttgatttt cattgagtat taaactaaat taaataatat tagcgcggag aatttctaat
    19981 tcttccttgg tcaagcgacg ccattcccct cgttccaggt tctcatctaa tactaaagtt
    20041 cccatagtca atcgttgcaa gtccaccact tccttgccac agtagcccac catacgcttg
    20101 atctgatgaa acttcccttc tgcaatggtc acacggattt ggctctgatt cttttctgta
    20161 tctatggata caagctccag tatagcgggt tgacaggtaa agtctttgag aggaataccc
    20221 tcagcaaatg tctccacatc ttcttgggtc atgattccct tgacttgtgc cagataagtc
    20281 ttatccacat gacgcttggg cgaaagaaga acatgagcca gctgaccatc attggtcaag
    20341 agcaaaagac catgcgtgtc aatatccaag cgtcctactg ggaaaacttc cttactccgc
    20401 gccaagtcat ccaacaagtc cagaacggtt ctgtgcttgg gatcctcagt cgctgagata
    20461 actcctttgg gcttgttcat catgtagtag acaaactctt catactccaa cacttgccca
    20521 tcaaagcgaa tctcatctat tttttcatca atctgcaatt tagctgattt ttctttttta
    20581 ccatttacag tcacgcgccc agccttgagc aagtttttga cctcagtccg acttcccacc
    20641 gcacaggcaa ctaaaaattt atctaatctc atagaactat tatatcatat caaaaggagg
    20701 ctggtacaat gaccaacctc cttttcgttt catactcttc aaaaatctct tcaaaccgcg
    20761 tcaacgtcgc cttgccgtat atatgttact gacttcgtca gttctatctg caacctcaaa
    20821 gcagtgcttt gagcaacctg cggctagttt cctagtttgc tctttgattt tcattgagta
    20881 tcagatttag gaaattaact tcctcgtctc caaaaaatag ctaaaacaat catggctcct
    20941 aaaatcgctg ggataatagc tgttcctgat aaaactggcc cccaagttcc aaagagcaag
    21001 tgacctagaa aggctccgat ccaaccgaga aacatttttc caaaacatcc cattcgctct
    21061 ccacgattgg tcatagcacc tgctaaaaat cccactagga gaccaacgaa catacttcct
    21121 aacatattat ctccttaatt tgcccaattc ccattacgga aaagaggtac ccgcgttcca
    21181 tcctcacgaa taccatcgat atccatttgg ttagaaccaa tcataaagtc tacgtgaaca
    21241 tctgaacggt taagccctgc agcttcaagc tcctcttcgc tcatctccgc tccatcaaca
    21301 acgctagtcg cataggctgc accgatagcc aagtggtttg acgcattttc atcgaaaagg
    21361 gtgttaaaga agataatgcc tgactgagaa attggacttg gatctggtac caaggcacat
    21421 tcacccaagg cacgcgcacc cgcattttca aagacaaggt ctttcataac ctgatcaccc
    21481 ttctcagcag tgatatctac gatttgtcca tccttaaagg tcaccttaat gccttcaatg
    21541 atatttccgt tgtagctaag cggttttgta gaagtgacat aaccatctgc acgacggaag
    21601 tcaggcgctg tgaagacctc ttctgtcggc atatttggca agaattcttc gccctgtgca
    21661 ttgacagcac cagctgattc ccaaacgtgg ttctttggca aaccaagtgt taaatctgtt
    21721 cctggcgctg tgtagtgaag ggctgaaaat tgctccttat taagcatatc ggccttgctc
    21781 ttgagaatgg ctgcatgttc ctcccaagcc ttaacaggat ctgcttcgta gacacgacaa
    21841 gttttgaaga tttgatccca aaggaaatca actgcttctt cgtcgctcgc agcatttggg
    21901 aagactttct tagcccactc aagtccagca gcggctgcta cagtccagct aaccttgtta
    21961 gattgagttg cgattcgcat tggcttcatg gcaagtccca tagctttagc agaagctgaa
    22021 agcttgtcag cgtccactcc gttcaaggca cctggatcag atgaacgaac cccaagacgg
    22081 ctagccttgt tctccaaaag atagttcatc tcagcaatct tgtattctgg cacattgtcc
    22141 aaacgctcca tcggggcatg gaggaatttc tcacggttaa tcacatcatc tgtccactga
    22201 acgatgacct catgcgcacc caaggcataa gcttctttca cgattagatg tgccaattca
    22261 cgttgctcca catcaataga gagagccaaa gtgtgaccag gttgcacgtt aattccgttc
    22321 gcaaccaaca atttcgcata tttttctaga ttttctttaa aatttggtaa aaccattctg
    22381 ttttctcttt tctattttta tttttctttc aaagcagaaa agattcctgc taaagcaata
    22441 gcacctgaca agagtgctgt cgatagaaga attgtacgat cagcaagttc taattgatat
    22501 tcaaatacct tcttagccgg cttatcttcc gcaaatattc ttagtttcat gagaaccccc
    22561 ttaaaataga ttaaaataaa tcactgtgac tgcctgtcct cagcaaattt aaaatcaatt
    22621 ccgacttgtc tactttataa accaaaagcc aatctggctg ggtatggcat tcacgaactc
    22681 cttgaaaatg cttggatgcc gtcaatgaat gatcacgata tctggcagga tgttcttttt
    22741 cttgaaccag aaaattcaaa acttcttcta ataattctgc cttcaaacca cgcttcatag
    22801 ccaacttaaa atctttttta aactgtttat gataacgaat cttaagcacg taagtcctcc
    22861 atcaaatctg agactgattc aaaagactgg ctcatattac gattttggtc taaatccgtt
    22921 aacgcttgga gcaacttccg attttcgtct agtctaacat caaaaggtaa tccctgatat
    22981 tgaattgcct gacgaaggaa aatattaata gctgttgtca tatccattcc cagattacta
    23041 aacacctgtt gggcctgctc cttaacctca ctatccagac ggatgcttat actcatcttt
    23101 gacatactct caccctcttt ccatagacta ttttaacaaa aaagaaagct aatgtaaatc
    23161 tattggatat acgttagcct cttttaatag attattaagc aattttttaa aacaactcat
    23221 caaacaaact caactggtta tcctctggca tatttccaag aatacccatc tcatccatct
    23281 tttcaaccaa ggttgatgag agtccaccac gcttgcgtag ttctgtttta gagaggaatt
    23341 ctccctcttc acgcgcccgc accagttgct tggcaacgtt ctctcccaga ccatccattg
    23401 ctacaaatgg tgggataagg gtatccccgt cgatgaggaa ctctgtcgcc tgactacggt
    23461 agagatctaa tttaccaaac ttgaaacctc gttcccacat ctcattgaca atctcaagag
    23521 ttgtatagag atcgatttcc acattagagg cttcattgtt cttccgtttt tcagagattt
    23581 cttccattct gcgcttgatg acctccaagc ccgcacccat ggtcttgata tcaaaagcct
    23641 tagcacgaat ggagaagtaa gcacagtagt aataaatagg atggtgaacc ttgaagtaag
    23701 ctacacgcaa ggccatcata acgtaggctg ccgcatgggc cttagggaac atgtacttaa
    23761 ttttcccaca ggattcgata taccactctg gcaccttatt agccttcatg gcttcgatat
    23821 agccatttct ctcctcttct gaaatcttta gccacaaacc cttacgtacc cgttccataa
    23881 tggtaaaagc catcttaggt tccagacccg catgcatgag gtaaaccatg atgtcgtccc
    23941 gacaaccgat aacagtcgat aggtctgcta ttccttgctt aatcagatcc tgagcattcc
    24001 ccaaccaaac gtcagtaccg tgggacagac cagacagctg aagcaattcc gcaaaggttg
    24061 tcggatgggt ttcgtctacc attccacgta cgaaatttgt tccaaactct ggaatcccca
    24121 acatacccgt aggcgttcca atttgttcag gtgttacccc tagtacatca gtcccagaaa
    24181 agagtgccat cacgccttcg tcatccatag gaattttatt agggtcaata ccagacaaat
    24241 cctgaagttt tcgaatcatg gtcggatcat catgtcccag tacatcgagt ttgaggacgt
    24301 tctcatcgat atcgtggaag ttaaagtgag tggtctgcca ttcagccgtg acatcatctg
    24361 ctggatactg gacaggcgta aaatcgtaga catccatgta gttcggaata acaacgattc
    24421 cccccgggtg ttggcctgtt gtccgcttga cacccgccgc tccttgagcg aggcgttcta
    24481 cttctgcatc acgataaaac ttgccataat ctcgctcgta acccttgaca aatccatagg
    24541 cagtcttggc agctaccgta ccaaccgttc ccgcacggaa ggcatattct tcaccaaaga
    24601 tatcacgcac atccaagtgg gcgctaggct gatcttctcc cgagaagttc aagtcaatat
    24661 caggaacctt atccccatca aaaccaagga aggtctcaaa cggaatatcc tgtccgtttt
    24721 tactgagttt gtgaccacag tttggacagt ccttatgggg catatcaaat cctgaaccgt
    24781 acgaaccatc tgtgataaac tcactgtact gacactgacc acagacatag tgaggagaga
    24841 gaggattgac ctccgtaatc ccaatcatgg tcgcaacgaa actagatccg acagacccac
    24901 gagaaccaac caaataaccc cgttcattag aacgttgcac cagcatctgc gatgccagat
    24961 aaatcacagc aaatccattc cccagtatgg atgttaattc tttttcaatc cgcaaatcaa
    25021 caatatctgg cagcggattt ccataaatct caaaagcttt cttataggtc aactcagcaa
    25081 ctgtttcttc agccttgtcg atgaaaggcg tatacaagtc acccttaacg acttcaacgg
    25141 gttcaaatat ttctgccaag gcattggtgt tttcaataac cagtttacga gccagttcct
    25201 ctcccaaaaa ggcaaattca tccaacatct cattagtcgt tcgaaaatga gcctttggaa
    25261 gtggcgctgg ttgggcatgt tcaccatgac cgatagttcg gttaatcatc gcaccctgtc
    25321 ccaaactacg gacgataatt tcacgataaa tctcttcttc cggttcgata tagtgaacat
    25381 ttcccgtagc cagaacaggc ttgccaaggc gatctccaac ctctatcaaa ctcttgataa
    25441 tggtctggag ttcctccata tccttgacct gctctttggc aatcaagggc gcatagatag
    25501 ccggtggcat gacctcgata aagtcataat acttggccac ctcaaccgcc gcatccacac
    25561 cttgagaaac gaccacgtca aaaacttcac cctctgaaca ggctgaacct aaaatcaagc
    25621 cctctcgatg ggcatctaga accgttctcg gaatccgtgg cactccttca aaatacttgg
    25681 tattagacaa ggaaaccagc ttaaagatat tttttagacc tacctgattc ttgacataga
    25741 tggtcgcatg cttgatccga gcttttttgt aagaatctgg actgattaga tcaatgttga
    25801 gtctagctaa atcggtcaca ccatgttttt ctgctacctc tttgataaag atgaaaagca
    25861 gacgaccagt cgcttccgca tcgtagttgg ccatgtggtg atgttccaag gccacaccaa
    25921 aacgcttggt caaaggcccc aaaccatggc gtttatactc aggatagagg tttctagcaa
    25981 actccagcgt atcaataact ggctgactaa tctttggaag atcatgacgc tcataattag
    26041 cattcataaa gccaacgtca aaggtagcat tgtgggcaac taggaccgta tccttgcaaa
    26101 attcttggaa ttcttgcaaa acttgttcta gtggtttggc atttttgaca tgatcatctg
    26161 taattccagt taactctgta gtaaaagctg acaagggatg cccaggattg ataaattcat
    26221 caaattcagc aataacattc cccttgtaca tcttagaggc cgcaacctga atcaagtcat
    26281 tatagatagc tgaaagtccc gtcgtttcca cgtcaaagac cacgtaggtt gcttctgata
    26341 agtccatctc cacttcgtta tagacgatag ggacacggtc ctccacgata ttggcttcca
    26401 tcccatagat cagctggatt cccgctttct tagccgcctt atagccatgt ggaaaggact
    26461 ggacattccc atggtctgtg atagcaaccg ccttgtgtcc ccacttagca gctgttgcaa
    26521 caatctcttc gacctctggc aaagcatcca tagtcgacat gttagtatga gcatgaaact
    26581 caacccgacg ctcaccttct ggcatcaaat ccttccgctc atagtgaaca acttcctgca
    26641 gatcctgtac gttcatagtc aaatcgcgtg tgaagttatt catctccaca ttccctcgaa
    26701 ctcggagcca agaattcttc ttgatgaggt caaacttctg ggcctcttcc tcgtttttaa
    26761 cccacttttg catagaaaaa cttgaagtat agtccgtcat tttaaagttg attaaaacac
    26821 gacctgttct agtcactttt tgctccacat caaaaacaac cccttcaaat accagacgat
    26881 tttcctctgt cgtcacttcg atcataggag taatctccgc cttatccagc ttgggtttag
    26941 ctgcagcttt tttcgcttga aaatcaaaga ctggtttctc ttccgctgga ggaggtgcca
    27001 tctgctccag ttgttccata gcacggagcg cttcctcatt ggcagcttga acaatctgct
    27061 cattttcagc atgaaaggcc tcttcctgct cttgggtcag gacatcattc ttctcgactt
    27121 gacagttaaa agttggaaaa ccaaactttt caagttgttt agctaaatta ggaagatgat
    27181 tcttcttaaa atgttcctta tcaatcgctt cagatccttc aataaatagc tgattaccct
    27241 cagcacgaac ttgcaaattt tgataaagga acttaaaacc ttgactagca catggacctt
    27301 cagagaaagc ctccctatag taggactgca agagctgatt tgaaaattct tgagaccgag
    27361 ccttaatttc aaaaacagct ttattgcctg tcttagaaaa ttcttcgctc aaacctttct
    27421 ttaattctaa aaagatttca atcggtaaaa tattagaaaa tacaaaatga aactcccata
    27481 ccttactaat tttatgaacc acaactcgct caatattggc ctgtgctaaa gcaggagcct
    27541 gtctcatttc agcaggcatc cccaattgat tcatcaaaat ttcaaaacta tttgacattc
    27601 attttcctca cattattctt ctactatttt accatattta gaggtatttt ctaaagacaa
    27661 aaggaagcca ctaagtgact tccttctaga gtgaggacgg attagtcttc acctttattt
    27721 ttcttaataa tttcttcttg tactgactta ggtacatctt cgtagtggtc aaataccatc
    27781 atgaatgtac cacgtccttg agatgcagaa cgaagaactg ttgcgtaacc gaacatttca
    27841 gcaagtggaa cgtaagcacg aacgatttgg ctgttaccgt gtgcttccat accatctaca
    27901 cgtccacgac gagcagttac gtgacccata acatcaccaa gattttcttc tggaacagtg
    27961 attgttacaa gcatcattgg ttcaaggata gctggttgtg ctgatttagc agcttcttta
    28021 agggaaagtg aagccgcaat cttgaaggca gtttcagatg agtcgacatc gtgatatgaa
    28081 ccatcataaa gcttagcttt aacgtcaacc attgggtaac ctgcaagaac accgttagcc
    28141 atagattcta ccaaaccttt ttcaaccgct gggataaatt cacgaggaac cacaccaccg
    28201 acgattgcgt tttcgaattc gaatccttta ccttcttcgt ttggagtaaa ttcaatccac
    28261 acatcaccga attgaccttt accaccagac tgacgtttga agaatccacg tgcttgggta
    28321 gaagcgcgga atgtttcacg gtaagatact tgaggagcac ctacgttcgc ttcaactttg
    28381 aactcacgac gcatacgatc aacaaggacg tcaaggtgaa gttcacccat acctgagata
    28441 actgtttcac cagtttcaac gtttgtttca acgcggaatg ttggatcttc ttcagccaat
    28501 ttttgaaggg cgatacccat cttgtcttgg tcagctttag attttggctc aaccatcaat
    28561 tggataactg gttctggaac gttgattgac tcaaggatga ttttagattt ttcatctgtc
    28621 aatgagtcac cagttgtagt atctttcaaa ccaacggcag cagcgatatc acctgagtaa
    28681 acagtgtcga tttcttgacg gctgttagcg tgcatttgaa ggatacgtcc gatacgttca
    28741 cgtttacctt tagaagtatt caatacgtat gaacctgatt gaagaacacc tgagtaaaca
    28801 cggaagaatg tcaaacgacc tacgaatggg tcagtcatga tcttgaaggc aagagctgca
    28861 aatggctctt cgtcagatgc tggacgagtt tcttcagcgt ctgtatctgg gttaatacct
    28921 ttgattgctg ggatgtcaag tgggcttgga aggtagtcga taaccgcatc aagcatcaat
    28981 tgaacacctt tgtttttgaa ggctgaacca cacaatactg gaaagaattc aacgttgata
    29041 gtcgctttac ggataccagc tttcaattct tcgttagtga tttcttcacc ttcgaggtat
    29101 ttcatcatca attcttcgtc agtttcagca actgcttcaa tcaatttttc acggtattct
    29161 tgagcttggt caaggtattc agctgggatg tcttcttcaa ggatatccgt accaaggtcg
    29221 ttagtataga tttcagcttt catcttgatc aagtcaatga taccacggaa gtcatcttca
    29281 gaaccgattg gcaattggat tgggtgtgca tttgcttgaa gacgatcgtg aagtgtgctt
    29341 acagagtaaa ggaagtcagc accgattttg tccattttgt tggcaaatac gatacgtgga
    29401 actccgtact cagttgcttg acgccaaact gtttcagttt gaggttcaac acctgattgt
    29461 gagtcaagaa cggtaaccgc accatccaat acacgaagag aacgttgtac ttcgattgtg
    29521 aagtccacgt gtcctggtgt gtcgatgatg tttacgcggt ggttgttcca ttgagctgtt
    29581 gtcgcagcag atgtgatcgt gataccacgt tcttgctctt gctccatcca gtccatttgt
    29641 gacgcacctt cgtgagtttc accgattttg tggattttac cagtgtagta aagaatacgc
    29701 tcagtagttg ttgttttacc ggcatcgacg tgagccatga taccgatatt acgagttttt
    29761 tcaagtgaaa attcgcgtgc catgaggttt gtttctccta tttatttttg atttctattc
    29821 tattataaca cgattttaat aaaaacggat aggcaggacc tacccgttct caatgttttc
    29881 atgctattgt tggtttcaac ttactagatg gtaagctgag ttatagctaa tactaatcga
    29941 tttagctaat ttgaacccgg gctaaagtta gttagccgat gtgagctgga acgggatgct
    30001 gcgtgaaaaa gataaaactc cttgtattcg ttgaatactg cgtcagtttc ctattttcac
    30061 cttgcatcct taccgtgcct agcatcatga tttagttgag ctcaagctaa aagtctggag
    30121 aaaaagatga atctcattgg ttgcaaccgc aacctgcttc gattccctat tttctctggg
    30181 actttcttaa cgctttcgca tcctatctta ccaacggaag tgtgcgaatg cacggttagc
    30241 ttcagccata cggtgagtat cttcacgttt cttaacagct gcaccagtgt tgttagcagc
    30301 atccaagatt tcttttgcaa gacggtcttg cattgtgtgt tcaccacgaa gacgagcgat
    30361 tgttaccaac caacgaagtc caagtgttgt acgacgttct ggacgaactt caactgggac
    30421 ttggtagtta gaaccaccaa cacgacgtgc acgtacttca agtacaggca tgatgttttc
    30481 catagctgtt tcaaatactt caagtgcatc gttgccagta gcttctttga tttgctcaaa
    30541 agcaccgtaa acgattgaag cagcagtacc acgtttacca tcaagcataa cgcggttgat
    30601 aagacgagta actagttgtg aattgtatag cggatctggc aatacgtcac gttttggagc
    30661 tctattttta cgactcattt ctctttatcc cctttcctta tgcttttgga cgtttagtac
    30721 cgtatttaga acggccttgt ttacgatcgt taacacctgc agtatcaagt gcaccacgga
    30781 cgatatggta acgtacccct ggaaggtctt ttacacgtcc accgcgaaga agcaccacgc
    30841 tgtgctcttg caagttgtgt ccgatacctg ggatgtaggc agtaacttcg ataaggttgc
    30901 tcaaacgtac acgagcgaat ttacgaaggg ctgagttagg ttttttaggt gtcattgttc
    30961 caacacgagt tgcaacacca cgtttttgtg gtgaagaaac gtttgtttga acttttttat
    31021 gactattgta accaacgttc aaagctggtg atttagattt ttctactttt gatttacgcg
    31081 gtttgcgaac caattggtta attgtaggca tctacattct cctgtgtttt tttatttttg
    31141 gtgatgatac acttggtgac agatatcatc tgtgtgtact tttgcaacat ttgtcagcac
    31201 gtccctgtac actcttgaga gaccaaaagt aaaaagtacc gtctatcatt gtaacaaaat
    31261 tttcccttgc ttgtcaagat atttttcatt tttattggta atgttagaga tcaatttctg
    31321 aataaaaata gctgggaaca catcatcttc ctaataatac ggcttggctt atgtgacatt
    31381 tttatctccg tcatttatac tgatatataa aatagtacag aaaacttctc aaaagtaaga
    31441 atttttttca caaatcaaag aaaacgcttg catattattt tactacatgc tatactgata
    31501 tagaaattta ttgattggag aatcattatg agaaaaacac catctcacac tgagaaaaaa
    31561 atggtctaca gcatccgttc cctcaaaaat ggaactggtt ctgtccttat cggcgcaagc
    31621 cttgtcttgc ttgccatggc tacaccaact atctcatccg acgaaagtac accaaccact
    31681 aacgaaccca acaacagaaa tacaaccacc cttgcccaac ctcttactga tacagcagct
    31741 ggctctggta agaacgaaag tgatatttct tcacctagaa atgcaaacgc ttccctagag
    31801 aaaacagaag aaaaacctgc aacagagcca actacttcta ctagtccagt aacaactgaa
    31861 actaaggcag aagagcccat cgaagataac tacttccgta tccatgtcaa aaaacttcct
    31921 gaagaaaaca aggatgctca aggactatgg acttgggacg atgttgaaaa accatctgaa
    31981 aactggccaa acggagcttt gtccttcaag gatgccaaga aagatgacta cggctattac
    32041 ctagatgtca aattaaaggg agaacaagcc aagaaaatta gcttcctcat caacaataca
    32101 gctggaaaaa atctaaccgg cgataaatct gtagaaaaac tagttccaaa aatgaacgag
    32161 gcttggttag accaagatta caaggttttc tcttacgagc cacagcctgc aggaactgtt
    32221 cgcgtcaact actaccgcac agatggcaac tatgacaaga aatctctctg gtactgggga
    32281 gatgtaaaaa atccaagtag cgctcaatgg cctgacggaa cagactttac ggctacaggc
    32341 aaatatggcc gctatatcga cattcctctt aatgaagccg caagagaatt tggattttta
    32401 ttactagatg agagcaaaca aggagacgac gtgaaaatcc gtaaagaaaa ttataagttc
    32461 acagatttga aaaatcatag ccaaattttc ctaaaagacg atgatgaatc gatttacaca
    32521 aatccatact atgtccatga tatccgtatg acaggagccc aacacgtagg cacttctagc
    32581 attgaaagta gcttttcaac acttgtcggt gctaaaaaag aagatatcct caaacactcc
    32641 aacatcacta atcacctagg aaacaaggta actattaccg atgttgcaat cgatgaagct
    32701 ggtaagaaag tgacctacag cggagatttc tctgacacaa aacatcctta tactgttagc
    32761 tacaattccg accaattcac taccaaaaca agctggcgcc tgaaagatga gacatacagc
    32821 tatgatggca aactgggagc tgacctaaaa gaagaaggaa aacaagttga tttgaccctt
    32881 tggtcaccaa gtgctgataa ggtttctgtt gttgtctacg acaagaatga ccctgacaaa
    32941 gtagttggaa ctgtcgctct tgaaaaaggg gaaagaggaa cttggaaaca aactctagac
    33001 agcacaaaca aactcggaat cacagatttc actggatact attatcaata ccaaatcgag
    33061 cgtcaaggta aaactgttct tgcactcgat ccttacgcta aatctcttgc tgcttggaat
    33121 agcgacgatg ccaagattga cgatgcccat aaagtggcta aagccgcctt tgtagatcca
    33181 gctaaactcg gacctcaaga cttgacttat ggtaagattc acaatttcaa gactcgtgaa
    33241 gacgccgtta tctacgaagc tcatgtgcgt gacttcactt cagatcctgc cattgcaaaa
    33301 gacttgacca aaccatttgg gacttttgaa gccttcattg aaaaactaga ctatctcaaa
    33361 gacttgggtg taacccatat ccagctcctt ccagtcttgt cttactactt tgtcaatgaa
    33421 ttgaaaaacc atgaacgctt gtctgactac gcttcaagca acagcaacta caactgggga
    33481 tatgaccctc aaaactactt ctccttgact ggtatgtact caagcgatcc taagaatcca
    33541 gaaaaacgaa tcgcagaatt taaaaacctc atcaacgaaa tccacaaacg tggtatggga
    33601 gctatcctag atgtcgttta taaccacaca gccaaagtcg atatctttga agacctagag
    33661 ccaaactact accactttat ggatgcagat ggcacacctc gaactagctt tggtggtgga
    33721 cgcttgggga caacccacca tatgaccaaa cggctcctag ttgactctat caaataccta
    33781 gttgatacct acaaagtgga tggcttccgc ttcgatatga tgggagacca tgacgccgct
    33841 tctatcgaag aagcttacaa ggctgcacgc gccctcaatc caaacctcat catgcttggt
    33901 gaaggttgga gaacctatgc cggtgatgaa aacatgccta ctaaagctgc tgaccaagat
    33961 tggatgaaac ataccgatac tgtcgctgtc ttttcagatg acatccgtaa caacctcaaa
    34021 tctggttatc caaacgaagg tcaacctgcc tttatcacag gtggcaagcg tgatgtcaac
    34081 accatcttta aaaatctcat tgctcaacca actaactttg aagctgacag ccctggagat
    34141 gtcatccaat acatagcagc ccatgataac ttgaccctct ttgacatcat tgcccagtct
    34201 atcaaaaaag acccaagcaa ggctgagaac tatgctgaaa tccaccgtcg tttacgactt
    34261 ggaaatctca tggtcttgac agctcaagga actccattta tccactccgg tcaggaatat
    34321 ggacgtacta aacaattccg tgacccagcc tacaagactc cagtagcaga ggataaggtt
    34381 ccaaacaaat ctcacttgtt gcgtgataag gacggcaacc catttgacta tccttacttc
    34441 atccatgatt cttacgattc tagcgatgca gtcaacaagt ttgactggac taaggctaca
    34501 gatggtaaag cttatcctga aaatgtcaag agccgtgact atatgaaagg tttgattgcc
    34561 cttcgtcaat ctacagatgc cttccgactt aagagtcttc aagatatcaa agaccgtgtc
    34621 cacctcatca ctgtcccagg ccaaaatggt gtggaaaaag aggatgtagt gattggctac
    34681 caaatcactg ctccaaacgg cgatatctac gcagtctttg tcaatgcgga tgaaaaagct
    34741 cgcgaattta atttgggaac tgcctttgca catctaagaa atgcggaagt tttggcagat
    34801 gaaaaccaag caggatcagt cgaaattgcc aacccgaaag gacttgaatg gactgaaaaa
    34861 ggcttgaaat tgaatgccct tacagctact gttcttcgag tctctcaaaa tggaactagc
    34921 catgagtcaa ctgcagaaga gaaaccagac tcaatccctt ccaagcctga acatcaaaat
    34981 gaagcttctc accctgcata tcaagaccca gctccagaag ctagacctga ttctactaaa
    35041 ccagatgcca aagtagctga tgcggaaaat aaacctagcc aagctacagc tgattcacaa
    35101 gctgaacaac cagcacaaga agcacaagca tcatctgtaa aagaagcggt tcaaaacgaa
    35161 tcggtagaaa actctagcaa gaaaaatata cctgcaaccc cagatagaca agctgaactt
    35221 ccaaatacag gaatcaaaaa cgaaaacaaa ctcctatttg caggaatcag cctccttgcg
    35281 ctccttggtc tcggtttctt actaaaaaat aaaaaagaga actaaactag ccctcctata
    35341 gaaaaatccc ccaagcatta tagctcgggg gattaatttt cgtacaatat ttgttgtcct
    35401 aataaacttg attaggattt tttattaagc ctctttcata gcaaaataag ctcgtacttt
    35461 gggtgcaact tgtgttccga agagttcaat agctctcaga acctggtcat gaggcataga
    35521 accaagcggt agatgaagca tgaagcggtc caatcctaaa tcctctatca tgcgaatcaa
    35581 tttttcggcc acctgatctg gattgccaac aaacatggcg ccatttgacc ctacctgatc
    35641 caaatattgc tcataacgca attcctgcca gtgcggacgg tctttggaaa tagcatccac
    35701 cacttgctta gtcggatgga aataatcttt caccgcctgc tcaccatctt ccgcaatcca
    35761 cccccaagaa tgggctccca ctttcaagtc tttgtcagca tggcccgctt cgcttccaat
    35821 ctcacgataa gcctgaatca actttttaaa ataacgtgga ttaccatcaa taatagcata
    35881 tacaatcggt agaccagcct gagcaatctt cactgttgat tcgacatgac cacctgtagc
    35941 tatccacaag ggcaatttgt cctgaactgg acgaggataa acttctttac cagcaatcgt
    36001 ttgagtcaat cgaccttgcc agtctaactt ggtcttttca ttgactaact gaagcaagtc
    36061 taatttctca tcaaaaagag agtcgtagtc tttcaagtca taaccaaaca gagggaaaga
    36121 ttccgtgaaa gagccccttc cagccataat ctccgctcgt ccatttgaca aagcatcgat
    36181 agtggcatac tgttggaaca aacgaatcgg gtccatgctt gacagaatgc tgactgcgct
    36241 ggtcaaacgg attttcttgg tattgactgc cccagcggcc aggacaatct ctggggctga
    36301 tactgcaaaa tccgcccgat ggtgctcgcc aatcccatat acgtccaaac caaccttgtc
    36361 agccagctca atctctgcca ccaactggcg aatgcgttca gcatgactgt aagtttgtcc
    36421 agtcccttca agctccgtta tttccccaaa tgttgaaatt cccaattcta ccattgtgat
    36481 tctccttgtc tatctctgtc cttcaatttg aaaaattatt ctaacacgaa tcttaagtac
    36541 aagcaaccaa tttgctcatt agaaaaagcc tagataacta gactttttta gcttattcta
    36601 ccgttactga tttagcaagg ttacgtggtt tatccacatc gaggccacgg tggagggttg
    36661 caaagtaagc gactaattgc gttggtacga ccattgaaat tggtgagagg tatggatgta
    36721 cggtcgtaag gacgatatcg tcggtatctt tggctacatt ctcttctgcg atagtgagga
    36781 ctttggcacc acgggctgcg acctcttgga tatttccacg agtatgattg gcaagaactg
    36841 gatctgacaa gagagccaaa acaggcgttc cttcttcaat caaggcaatg gttccgtgct
    36901 tgagttctcc tgcagcaaag ccttcacact ggatataaga aatctctttg agtttgagac
    36961 ttgcttccat ggctacgtag taatcttgac cacgtccgat gtaaaaggcg ttacgagttg
    37021 tttcaagaag ttcacgaacc ttggcttcaa tggtttcttt ctctgaaaga gttgattcga
    37081 tagactgagc tacgattgac aattcatgaa tcaggtcaaa ggcttgcgct ttagcattac
    37141 catttgcttc tccgactgct tttgcaagga aggcaagggc tgcgatttgc gctgtatagg
    37201 ctttagttga tgccacggca atttcaggac ctgcgtgaag gagcatggta tagttggctt
    37261 cacgtgagag ggttgagcct ggaacatttg tcactgttaa gcttggaatt cccatttcat
    37321 tagccttgac caaaacttga cgactatccg ctgtttcacc agattggctg ataaagatga
    37381 agagtggttt cttgctgaga agtggcatac cgtagcccca ctcagatgag atgccaagtt
    37441 caactggtgt atctgtcaat tcttccaaca ttttcttaga agcaaatcct gcatggtaag
    37501 atgttccagc tgcaaggatg tagatgcggt ctgcgtcttg aacagcctta atgatagcag
    37561 gatcaaccac tacttgacca gcatcatccg tgtaggcttg aatgagttta cgcataacag
    37621 ttggttgctc gtcaatttcc ttgagcatgt agtaagggta agttccctta ccgatatctg
    37681 acaagtcaag ttcagcagtg tagctagcac gctcacgacg atttccatca tagtcttgaa
    37741 cttccacact atcagccttg acgattacca actcttggtc atggatttcc atgtattggt
    37801 tagtttcacg aatcatagcc atggcgtctg agcagaccat gttatagcct tctccaagac
    37861 caatcaaaag tggtgattta tttttagcta cgtagatgac ttcaggatct tgtgagtcaa
    37921 ccaaggcaaa ggcataagaa ccacggatga tgtgaagggc ttttttgaag gcttcaagaa
    37981 ctgagagccc ttcttcttcc gcaaattttc caatcaaatg aacggctatt tcagtatctg
    38041 tctgcccctt gaagtggtga cctgcaaggt attcttcctt gatttcaaga tagttctcaa
    38101 tcaccccatt atgcaccaag acaaaacgtt ctgtctcaga gcggtgtggg tgagcattgt
    38161 cctcagttgg ttttccgtga gtagcccaac gagtatgtcc gataccagtt gttccctcaa
    38221 caccagctgt cttggcagac aattctgcaa tacgaccaac cgccttcacc aaatggttat
    38281 cagcaccatc taggacaaaa attcccgcag aatcatagcc acggtattca agcttttcaa
    38341 gcccttgaat caaaatatca gttgcatttg tgtttccaac aacaccaaca attccacaca
    38401 tagtatatac gacacaggca agctgtgctt tctccttaaa attggtatag tctaattcat
    38461 cttttataga atcagcaaaa acagtatata cttgtttctt tcacttgtca agagtaaaaa
    38521 ttggtatagt tcaaattaag ctcctgtaag caaaaaactc tgaccgattg ggataatcag
    38581 tcagagtcct ttttaaaatc cattattgtc gcttagtttc ttgaaccagt ggcctgattt
    38641 cttcagacga cgttcttgcg tttccaagtc taattcgacc aaaccatagc gatttttata
    38701 gctgttgagc catgaccagc agtcaataaa ggtccaaatc aagtagccct tacagttggc
    38761 accatcttca atggcacggt gaagttcacg aagatgacct tttacaaagt caatacggta
    38821 atcatcttga atcattccat cttgacggaa tttttcttcc ccttcaacac ccataccatt
    38881 ctcagtcaac atccactcaa tattgccata attttccttg atattttggg cgatgtcata
    38941 aatcccttgc tcataaatct cccaaccacg atgagaattg attttacgtc caggcatcac
    39001 ataaggctcg taaaaatgtt ctggtaagag tggactctct ggatgcttag caaatcgagg
    39061 agccataaca cgcaaaggtt gatagtagtt cacaccaagg aagtccaccg tattatcacg
    39121 aatgagttcc aactcttcct ctgtagcatc aggtaaaaga ccgtgttcat gcaagatttc
    39181 taccaactcc tgtggataag tccccaagac agatggatct aagaaagatt gggcctgaaa
    39241 aagggccgca atacgagctg ccttgacatc agcaggatgc tggctacgtg gataagccgg
    39301 tgtcaagttg aggacaatcc caatcttgga atcaggcaaa agttcatggc aagccttaac
    39361 agcccggctg ctggccaatt gtgtatgata ggctacctta acagctgcct ctgcatccac
    39421 cttatgtgga taatgggcat cataaaaata accaaattct acaggaacga tgggctcgtt
    39481 aaaggtaatc cattgatcca ctaaatctcc ataagtctca aaacaaaaac gagcatagtc
    39541 ttcataggct gagactgtcg ccttattttc ccaaccatca ccatcctctt gaagggcaaa
    39601 aggtaaatca aaatgataga gattgactaa cagacaaatt cctttagcct taatagcctc
    39661 aaagacctta cgataaaaat ccacaccttg agggttgact tttccacagc cttgtggaaa
    39721 aatccgtgac cactgaatag aagtccgaaa gactgtgtga ccagtctcta acaaaagctc
    39781 aatatcccgc tcccaatttt cataaaaagt cgatgtctta tctgaaccaa tcccattata
    39841 gtaacgattt ggctccactt ggaaccagta atcccagaga ttgtctccct taccgtcacc
    39901 agctacacgt ccttctgtct gcggtccaga agtagaggat ccccagacaa aatcctttgg
    39961 aaatcttagc ataacattta cctctttatc tactcatttc tcccattata cagaaaaaac
    40021 aaggtaaaaa ctagttacat tttttccttg tttttcttct gattatagtt tttatttctt
    40081 gcttaggatt tcaagcgttt caagcacgtt atctgcatga acctcaatgg tgtcaccagt
    40141 tgccttgatc ttaacttcta caatgccatc ggccgctttt ttaccaacag tgatacggat
    40201 tggaagacca atcaagtcac tatcgctaaa tttaacaccg acacgttcgt tacggtcatc
    40261 tgtcaagact tcataaccag ctcccatcaa gcttgcttca agtttttctg tcaaggcttg
    40321 cgcttcttca tccttgacat tgacagtaat caaatgcaca tcaaatggtg ccaattcttt
    40381 agggaaattg attccccaag cgtaacggta ttcacctttt ggcgttttgt taacaaagag
    40441 gcgagcgtgt tgctccatca ctgctgaaag aagacggctg acaccgatac cgtaacatcc
    40501 catgatgatt ggcacagcac gaccattttc atccaagaca tctgctccca tgcttgctga
    40561 gtagcgagtt ccgagtttga aaatatgacc gatctcaata ccacgcgcaa agttaaggac
    40621 accttgtcca tctggggaaa tttcaccctc acgaacttca cggatatcca catattctgc
    40681 agtaaaatca cggcctgggt tcacaccagt caagtggtag ccatcttcgt tagcaccgac
    40741 aactgcattg cgaacatctt gcaccttacg atctgcaata attttaatat tctctggcaa
    40801 accaactggt ccaagtgaac caaatcctgc ttgaacaaca ttcgccactt cttcttcgct
    40861 agcaacgtca aagaaatctg ctcccaagtg gtttttcaac ttgacttcgt tgagttggtc
    40921 atttccaact agaagggctg caacaagctc accatctgca atgtagaaga gggttttaat
    40981 cgtttgttct tctggaacat tgaggaaagc tgcaacttca tcaattgatt taacatctgg
    41041 cgttgcaaca cgagtaactt cttcttcagc gacaacacgg ttgcttggtt tgtactcgtt
    41101 tgttgccatt tctaagttag ctgcatagct agactcactt gagtaagcaa tggtatcttc
    41161 accagagact atccatttga gcaattctgc cttgatttct tcttgcactt ctgcaggaat
    41221 ttcgtcaaat gaggcaactg acttgtccaa gacaacccag cggtcaaggt ctgtacgagc
    41281 agatgtaatg gccataaatt cttggctatc cttaccaccc atggctccac cgtcaccaat
    41341 aatagccttg aagtctaaac cactacgagt gaaaatacgc tcataggctg ctttgtactc
    41401 atcataaaca ctatccaaac tatcatagtt agcgtggaaa ctataagcat ccttcatgat
    41461 aaactcacgt gtacgaagaa gtccattacg tgggcgtttt tcatcacgat acttgggctg
    41521 aatttgataa aggttgagtg gcaattgctt gtaagattta acagaatcac ggacaatagc
    41581 tgtaaaggtt tcttcgtgag ttggacctaa gataaagtct gatttttcac ggtttttcag
    41641 tttgtaaagg tcttcaccat aggtttcgta acgacctgat tcacgccaca attctgcact
    41701 aagaagggct ggagccaaca tctcaacagc accaatcttt tcgaattctt ggcgcatgat
    41761 gtttttagct ttttcaatca cacggttggc aagtggtaga taagaataaa cacctgctga
    41821 aacttggcga acataaccag cacgcaacat aagagcatgg ctgataactt gagcatcgct
    41881 tggcatttcg cgaagcgttg ggataggcat tttactttgt ttcataatat tcctcgatta
    41941 tctaaaaaag agtcgcataa tgtcattcca agttacagca atcatcaaga caaccatgat
    42001 gaccactccg gccaaggtga cataggtttc aatttcttgt ttcaatggtt tgcggcggat
    42061 ggcttctagg atattgagca caatcttacc accatccaag gctggaatcg gaataagatt
    42121 aaaaatccca atattgatgg aaatcattgc caagaagtac aagatatttt caattccatt
    42181 tttagcagca tcactacttg ccttaaagat agcaacaggt ccacccaact tgttcaaatc
    42241 cggttggaaa atcagatttt tcagagctga gagaattcgg agagctgagt cagcagcagt
    42301 tgtaaaacca cctacaaaca tggatagaaa atctgactta acccccggtt gaacacctag
    42361 aaggtaacga ccttgactat cttcgggtgt aacagtgact tgtttgtcac tccccttttc
    42421 agaaatagtc acatccaaag tcggtgccgt cttatctttg gtttctgttt ccacagcttg
    42481 gatcaagctt tcccagttgc taacctcatg tgagccaatc ttggtaattt gtgccgtttc
    42541 tggtactcct accttggcca aggcaccttg gggcatgata tggaactgat tggtatcaac
    42601 atctctgaca ccaccctgca taaagattaa aacccaaaaa acaacgacac ctaagataaa
    42661 attgttcata ggacctgcaa aattggtaat cagtttgccc cagatagtcg cattttgata
    42721 ttgaacatct aaaggtgcaa tccgaacctc agtaccatct gcttccacaa ccgttgcatc
    42781 gtgatccact gcaaatgttt tttcttcttc cagaaccaat cctttgataa agagcttgtc
    42841 ttcaaaatca aactgggtca cctgcatagg gagggctgtt tgatccaatt ttttacctga
    42901 gagattgatg cgtttaacct taccatcatc agcaagtgtc aaactaacag gcgttcctgt
    42961 cttgatttca gttgtatcat caccccaacc ggccatgcgg acatagccac ccagaggcaa
    43021 aattcgaatg gtataggccg ttccatcctt accaatgtga gcaaaaattt taggtcccat
    43081 accgatggca aattcacgta ctaaaatccc tgatttcttg gcaaagtaga agtgcccgaa
    43141 ctcgtgcacc actacaataa tcccgaaaac cagaataaag gttaaaattc cgagcatagc
    43201 gtttcctccg tcttttgatt aaaagagtcc aaataagtgc atgattggaa atacaagcaa
    43261 catactatcg aaacgatcca aaacaccacc atgtccaggg ataaatttcc cagaatcctt
    43321 aacaccaaaa tgacgtttga tcgaactttc tagtaaatca ccaaattgtc cagcaatgct
    43381 aaagaaaata gcaaagactg acatcttgta aattccatat ggaagagcaa ctgtactgtc
    43441 aactatcata aagataatgg ttactaaaat tgctcctaaa ataccaccca aggcaccctc
    43501 aagggtttta ttaggcgata cccttggtgc taactttcgt ttcccatagt tcatcccaac
    43561 aagataggca ccactgtctg tcgcccagac gatacacaag gctaagagag ccttgtccaa
    43621 acctgcaaca cgagcatcta gtaaagcatt aaatccaaag cccacgtaga agctcatagc
    43681 aagagggaaa accgcatcct caatcgtata agacttgcta aaaacggtcg ttcctaacat
    43741 gattgaaatc aaaacactat aggcaaccac attcccatca actggcaaaa aagtcaggta
    43801 attctccaag ggaatggtca atgcaaaggt tgcaaagagg gtcaagaggc cctccatcgt
    43861 catggtctct agacctctca tcttcaaaag ttcatgcatg gctagcatgg ctatgattcc
    43921 gattgctatc tgaagcaaga ggcccccaat cattaaaatt ggtaggaaaa tagccagggc
    43981 aatccctgca aacaaggttc ttttctgtaa atcctgggtc atatttcctc ctaaactcct
    44041 ccaaatcggc gatgacgacg attataggca agaatagctt cctgcaaggc cgcttcgtca
    44101 aaatcaggcc ataaggtgtc cgtaaaataa agctcactat aggctccctg ccatggaagg
    44161 aaattgctca aacgtaattc tccactagta cggataatca agtctgggtc tcgtaagtcc
    44221 ttaggcaaat gctgagtaaa gagatagtta ccaatcaatt cctctgtgat gtcacctggg
    44281 ttgattttgg catctaaaac atcctgggaa atcaacttaa gcgcctgtgt aatctcagca
    44341 cgtccaccat agttaagagc aaaattaaga atcaatcctg tgttgttctt agtcaattcc
    44401 tcagccttgg ttaaagcttc aaaggtttgc ttaggcaggc ggtctgtctc cccaatcatt
    44461 tgaatcttaa cattattcgc atgtagttcc gggacataat tatcataaaa ctctactggc
    44521 aagttcatga taaacttgac ttcctgatct ggacgggtcc agttttccgt agaaaaagca
    44581 tagaccgtaa taaccttgac gcccagtttg ttggctgcct tggtcacggt ttgcaatgct
    44641 tccatgcccg ccttatgtcc aaaaactcgc ggttgcatac gttttttagc ccaacggcca
    44701 ttaccatcca tgatgatgcc gatatgagca ggaacctgtg tcggaacctc tacttccaca
    44761 gccttatctt tcttaaaaaa tccaaacatg atcttattcc tattcaaaaa tctatcgttt
    44821 cattatacca tatttcccca ttttcttcta tcactaagct atttattctc aggcaccatg
    44881 cccatttttc aaaaaaataa gccgcctgat tgggcgactt tatttttata gggagattat
    44941 tatgaaaaag ttttaggagt ttaagttaag gtcttcttaa cttatgaact tagtgtacac
    45001 tccctagctt aaagtttcct taagtatttt taaaaatcaa atttttccat ttctcctgcc
    45061 aatttttctt ggataaacgt gtttgataga gttccattcg gtcttcattt tctaagaaat
    45121 gaggagttgg acgaacttga aaattcaaaa tatcctccaa accataaggt gcatagagtt
    45181 caaaatctga ttcttcattc aagcgcagtc caactgccgt acaccgttct ggatacttac
    45241 tcatagcatc acgagaactg gtataggaag cagtgtgagg actgtgctga tgcatataga
    45301 cctgattttt caattcccac tggtactgag gaaaatcctc tctcagcttt ttctccagta
    45361 ataaggtttc ctcataagaa aaatctggat caaagaaaat cacatctata tctgtttcat
    45421 gatcaaaagg ggatttgtct gacaaaagat tccagatgaa atttctgaca gaacctgctg
    45481 ccaactacga gtctttcaaa ccaaggtctc ggatgatcgt cagaatggcc atcatatctg
    45541 gattttctct aaaagcctct aagatttctt gcttattttt cactgtattc ataacctaag
    45601 tgctcatatg ccttagcagt cgccacccgt ccagaccgtg tccgcatgat aaaacctttt
    45661 tgaatcaagt aaggctcata catgtcttca actgtctcac gctcttcggc gatattgaca
    45721 gaaagagttc ctagaccaac aggtcctcca ctgtacatct caatcatggt acgaaggatt
    45781 ttttgatcca catagtccaa accttcatgg tcaacatcca gcatagtcaa agccttatcg
    45841 gtaataatat catcgattac cccattcccc attatctggg caaaatcgcg cacgcgcttg
    45901 aggagacgat tggcaatacg aggggttcca cgactacgta gggccaactc agatgctgcc
    45961 tcatgagtga tttccatctc aaaaatatct gccgtccgct cgacaatttc tgtcaagtca
    46021 gcatgggcat aatactccat atgacctgta atcccaaaac gtgcccgtag tggatttgag
    46081 agcataccag cccgagtcgt cgcaccaatc aaggtaaaag gaggcaactc caaatgaaca
    46141 ctgcgactgc cttcaccagc cccaatcata atatcgatgt agaagtcctc catggcacta
    46201 taaagcactt cttccactga catgggtaag cgatgaatct cgtcaataaa gaggacatct
    46261 ccaggctcta actcattcaa aatcgctacc aaatcacccg ctttttcgat aacaggacca
    46321 gacgtttgct tgagattgac tcccagttca ttggcaatga caaaagccat ggttgttttc
    46381 cccaaacctg gaggcccaaa taagaggaca tgatccagcg cttcatctcg cattttggca
    46441 gcttctataa agatttgaag ctggtcctta accttatcct gcccaatata ttcacgtaaa
    46501 tactgaggac ggagcgtgcg ttctactaac tcctcatccc ccattatctc attatctaaa
    46561 attctactca tggctctatt atatcaaaaa accaagccac aaacaaaaaa gccacctgat
    46621 tgggtgactc ctaagtttag cacttatgtg gtataatatt ctacgacact gctacaccgc
    46681 ctacgaaagg aggtgagata gcccatgatg gaattagtac tcaaaactat catcggacca
    46741 attgtggtcg gtgtcgttct tcgtatagtc gataaatggc taaacaagga caaatagtgt
    46801 caaaaaagac cccaagctta tttggtcgtg agcttggggt cttttctagc ctatgatata
    46861 gaactagtac tcaattcctt tttattatcc catagttcac gaattttgtc aaaggtttac
    46921 attttcttca accgctgtac gacaagacgg ttaagattaa gagaacgtta gggattctat
    46981 caatttcata gaaattttga tttcgtaaac gaagagacaa tcttacatgt cacttctcat
    47041 ttaatacgcc actactagac aagcaaaatc attattacag tagttccagt tcttcaatta
    47101 acagtcactt acaatcaaat tgagtttgaa ctagctgaag cgaccacaga cctatttctt
    47161 agttatattc gctaaaaaag tccccgccaa ttccccgacc aaaatccgaa aaataccgaa
    47221 aaatatcgaa aaattatttt tagaatagtc cccaaaagcc tgaaatagag ctaaaaaact
    47281 ccacctgatt gggtggagtt aagggagatt attatgaaaa agaaaagttt aggattttat
    47341 taaataaagt taggaggtct ttatttaata actacatgat acaagacgaa acttaaaact
    47401 agcttaactt ttctaaaatt ttactatttt gcaaaaaatt tctatcacca gcacctcacc
    47461 acgcaaaaaa gccacctgat tgggtggctt cattaggaga ttgtgatgaa aaaagtttag
    47521 gattttatta aataaagtta ggaggtcttt atttaatgac tatataatac tagaccatcc
    47581 ttaaattttg cttaagaaaa aacaagtttt gttatttttc tcgattcgcc caagtcatcc
    47641 ctatacaatt ataggtggat aagatttcaa agcccataga acgataaaat cccacgtttt
    47701 tttctgtctc ttctgtcacc agctggactt gataagcatc tttgtaatct tttaaggcct
    47761 ctttcattag ggcactacca atcccttgac gctgatagat tggtaaaaca atcaaatcct
    47821 gtacaaaaac tgatgagaat ccatctccaa ccaaacgaat caagcccacc acagcatcac
    47881 catcaagtgc cagataaatt actaatgaat gcgataaggc atgctccagc atctctggtt
    47941 gatgggtata atttgtccaa ccgacagcct gatagagatg caaaacatcc tctagcttga
    48001 caatttcttg ctttttaata gtaatcatct caacacctct taaagttctc tcaagctctt
    48061 gtactgctgt ccatttttat caaaattttc aggacgcagc catgtttcca aacgatcttt
    48121 gacttgaggc cagtccatat caatcataga caaccaatcc gtatctctcg tacgcccctt
    48181 ataaaccacc gcctggcgga aggttccttc atagacaaat cccaaacgct ccgcaactcg
    48241 tctggatggc agatttaagg catcgcattt ccactcgtag cgacgatagt ttagctcctc
    48301 aaaaatatag cgagctagga gatactgagc ctcagttcct atccgtgtac cccttagctc
    48361 tggagaaaaa gtgactgctc cgacttctat tactcggtta ttctggtcaa tgcgcatgag
    48421 agaaaaagtt cccaaagcct taccagtcgc cttgtctatg attgcatagt aaaaacggtc
    48481 cttacgagcc aacatctgat ttaaaaggct aaccagctcc cccatatctg ctactggctc
    48541 ctgaaaaaga taggtccaca tctcccgagg agtatccggg ccataaacag ctagcaaatc
    48601 ctccgcatgt ttttctaccg agagagcctc tatcctagca taacgccctt ctaagaaatc
    48661 aatagaaggc agtgcaccgg gtgtataacc ttccattgac tcaccaatca tctgaccata
    48721 ttcatttact ggcatagctt tctccttgtt tcacttttca aactttttac tcaactctat
    48781 ttgaattgtc ctatctgcta atttcaagtt ttttatcaat ttcatttaac aatttttctg
    48841 catcttcttt atttaaaaca ttttctcgtg ctacatagtt tctacaaata ttcagggccg
    48901 caatttggtc tgctttatcc aaagattcaa acataattct cactgagtta ctagcaataa
    48961 ctcctcgttt atcatccgaa ttttgaagaa agttaagtag aacacttaaa ttgttctgac
    49021 gacacgattc gtacaaatca atatattcac cgtatttttt cgattcagaa tcagtaagtt
    49081 tatctacaac ttttacctgc gaataaaaat agattatttc cctattttga ataatataat
    49141 ttatttttct gatatatttt aatccctcta ttaagagcca aataaaatag attatcagaa
    49201 taccaaacag tggtagccac atgataccaa cactggattg aatacgagga taagtttcat
    49261 taaaagaaac tattaaattt ttggctccaa aataatgaat aatggataac aaatttgtca
    49321 ctattaatag agttgcaaaa gattttgtaa ataaaaattg atacacttca gactgtgtcc
    49381 ttataatttc atttggagat attccaaaaa tattgcttga tttatcattt gaaaaactaa
    49441 agaaagtaat aaaaactgca aagagagtgt ctaaagtgag tatcaaattt aaactttcct
    49501 tgtcccaaag acaattttta aaataatatg cacccactat tgacattact aatactataa
    49561 ctgacactac aataatagaa atcttaaata ataaaatttc acacttcctg ctatcgttca
    49621 ctaatctatt cattctgacc tattctaaaa gtaactctaa agttcatact ctagagttac
    49681 ttctttttat ttcacaacaa tgttaactaa tttagttggc ttcaatagtc cagtggacta
    49741 ttgaaggtgg cagatagagc taataaactc gttatttaac gacgatatta acgagtttat
    49801 tcggtaccgc aattactttc acgatttcct taccgtcaat ttctgctttg actttttcat
    49861 cagctaaagc gatttcttgt aattcttcac gtgatagatc tttagcaacc atgagtttgg
    49921 cacgaacttt tcctttgatt tggacgacaa tttcaatttc atcttcaacc aatttgcttt
    49981 cgtcccaagt tggccaagct acataagaga ttgactcacc tgtttctgcg actgtttgcc
    50041 agagttcttc tgccaagtga ggtgcaaatg gtgcaatcaa ttgaataaag cctttggcat
    50101 agtcaatata aagcttatct tccttgttag cagcattgac aaagaccata agttgggcaa
    50161 tagctgtgtt gaatttgaga gactcaattt gctcagtaac agctttgact gtttcgttgt
    50221 aagccttgtc aagagcacca ttgttttccg caaggatttc tttacttgta atcaaacggt
    50281 aaactcggtc aaggaactta cggcttcctt ccaaaccttc ttctgaccaa gcaatcgaag
    50341 catcgagtgg tcccataaac atttcataaa cacgaagggt atcggcaccg tattgttcca
    50401 ccacatcgtc tgggttaaca acgttcttga gcgatttaga catcttggct ggcgcttgct
    50461 ccaactcttc ccctgtttct acatggaaga aggaaccatc acgtttttca accttgtcgg
    50521 ttgtcacaag agcaccacgg tggtcacggt agcttgttcc caaaatcatc ccttggttaa
    50581 agagtttttg gaatggttcc ttagtcggaa caacaccgag gtcatagagg aatttatgcc
    50641 agaaacgagc ataaagcaag tgaagtacag catgttccgc accacccacg tagatatcta
    50701 ctggcaacca ttgtttgagg aggtcctcat cagccaattt ctcagtattg tgcgggtcaa
    50761 tatagcgaag gtagtaccag cttgaaccag cccattgtgg catggtgtta gtttcacgac
    50821 gacctttgac accatcttca cgagtcactt caagccagtc tgtcaagtta gctagtggac
    50881 tttcaccggt acctgaagga cggatgtcct tggtgacagg caagacaagc ggcaattcag
    50941 tttcaggaac agctgttgaa gttccatctt cccaatgaat aattggaatt ggttcacccc
    51001 agtaacgttg acggctaaag agccagtcgc ggagacggta ggtaaccttc tcctgaccac
    51061 agcctttttc ttccaagtaa gccacaatct tggcaatagc gtcttctttg ttcaatccat
    51121 ctaggaagtc tgaattgaca tgcaggccat cctctgtgta ggcagcttct tcgacatttc
    51181 caccttcaag tacttcgacg attggaaggt caaattgttt ggcaaattcc cagtcacgtt
    51241 ggtcgtgggc aggcacagcc ataaccgcac ctgttccata actagcaaga acatagtccg
    51301 caatccagat tggcatttcc ttaccattga cagggttgat ggcataagca ccagtccaaa
    51361 caccagtttt ttccttagca aggtctgtac gaaccaagtc agacttaagg ctggcttggt
    51421 gtttatagtc tgctacagct tctgcttgct ctgaacttgt gatagcgtct actaattcat
    51481 gttcaggagc caagacagtg aaagtcgcac cgaaaagtgt gtccggacga gtagtaaaga
    51541 ctgtaaattc cttgtctgtt ccttttactt tgaaagttac attggcacca gttgatttac
    51601 caatccagtt gcgttgcata tccttgatag actctgacca atctagttca tctaagtcat
    51661 tgagcaagcg ctctgcgtaa gccgtgattt tgagcatcca ttggcgcatt ggtttgcgga
    51721 caactggata gcctccacgc tcagaagttc cgtcaggaag cacttcttca ttggcaatgg
    51781 cagttcccaa ttcctcaacc cagtttactg gcacttcagc ttcataggcc aagccttttt
    51841 cgtaaagctt ggtgaaaatc cattgagtcc acttgtagta gtttggatct gttgtgttga
    51901 cttcacgatc ccagtcataa gaaaatccaa gcgcattgat ctgacgtttg aagttggcaa
    51961 tgttttccgc tgtaaattct gctgggtcat taccagtatc catagcgtat tgctctgcag
    52021 gcaaaccaaa agcatcccaa cccattgggt gaaggacatt gtagccttgc gcacgtttgt
    52081 aacgactgag gatatcggtt gcagtataac cttctgggtg tcctacgtgc agaccagctc
    52141 cagacggata agggaacata tcaagcgcat aaaacttagg ttttgatgca tctgttcctg
    52201 tcttaaatgt atgatgttct gcccagtagc cctgccactt aggctcaatt tctttatgat
    52261 tataaaaact catggtctct ctccaatttt gtgatgttac tattatacca tttttgaggg
    52321 aatttgaaat gtgtttaaag aaaaaactgt atactgtatc tcattaattt tgatgactat
    52381 gaattgctct atctcccact ttttatccca ttgttatgca gtaaatcaag gagtaagtca
    52441 agaagcttat ctcgtatagc acaaaatact tattttagac cgaagataaa actggaatgc
    52501 taattaatgt attcacaata aatagccgac tacctatgtc gctttttgat ttatgaagaa
    52561 cgtatagtag actgaatctg aaatagtacg aaacaattgc taaaacattt atagaaatta
    52621 attttacttt cccaatcgat ttgttctcat cctatttcaa tcttctatag aattcaatac
    52681 agggatcaat aaaagactac catttggaaa acagtagtcc ttattgttta ttttgaattt
    52741 acataggcat ctacagcgat aatagcttga gcaacatctg aaggcgaaat cttaaacggc
    52801 atctgatgaa ttgtctcacc ctccatagtt gcttgtttac caacttttat taaatcatca
    52861 tatccaactt gatccaaatg catttctttt agagttgttg gcataccaat ttttttgtaa
    52921 aactcaatat acttatcaag ttcttcttta ggtctatttt ccaataatag ttgtactaaa
    52981 gttccataag ctactttttc accatgtgtt aaatgatgaa tgtcacctgt caatgcagta
    53041 aaaccattat gaattgcatg cgccgcagct aatcctccac tttcaaaacc tagaccactc
    53101 aataaagtat tagcttcaac aatattttct aatgctggtg tcaccacttt agcttcacaa
    53161 gctgccatag cctgtaaacc atctgcaaac agcgtttctt cacatttctt cgcaattgca
    53221 actccagcca atgtttgctg ttgtcccaac atagtttttc catttgcctg cataaccgca
    53281 cgcgcctcaa cccaagttgc taaaccatct gcaataccag acgctaataa acgcttaggg
    53341 gcttgtgaaa taacttttgt atcaaccaaa actaaatctg gatttttaga ataaaataga
    53401 taatgatcaa atgcaccttc atctgtataa ataacagata aagcagatac aggtgcgtcg
    53461 gtcgatgcaa ttgttggagc aataataaca ggcttttcaa tcaaatctgc aatagctttt
    53521 gcgctatcaa tcgtctttcc cccaccaaga ccgataatac tatcacaatt ttctttctca
    53581 gccaaggcaa caactcgatt gatttcattg tcagaagctt caccattaaa tagcgccaga
    53641 acaatatgga aaccatacct atgtaggtaa tcttcaaatc gttttccaac aatatcataa
    53701 accaactgat cgcataatag aatagggcaa tttcccaaat ccaaaattga tttggcattt
    53761 tcaaacaagg cattttcccc ctgaatatat ctagaaggac tagcaaaaat tctcatatgt
    53821 atttcctctc tatctaaatg gaacgactat tttgaataac aaaccaatcg tcagaaaaat
    53881 catcaaccgc cttttggata gatggcatgg cgaaagctga ttcaaaaaca tccgctcctg
    53941 ctgtaacagc atgcgcacct gcagctaaag cattatttac ttgtgctaca tttttaaagg
    54001 atgcagccaa aatcttacta ggagagttct gtctatcaat agcaagaact aattgacgaa
    54061 tgacagaatt tgaatcaatg ttcagatttt ccattctatt ataatatgga gctaggtaat
    54121 ccgctcctgc ttcgatagct aataatccct gaataactgt ataaatagct gttgcagtga
    54181 tatggtagcc ctcttttttt agcaccttta ttgcacgtaa tccagctgga gtaacaggta
    54241 ctttgataaa tatatcatct cctgcttgtc ttcgaatttc atgagcatcc tttaagatgc
    54301 cttcaaaatc ttgagaaatc acctgaacat gaatagaggg tgtagagcca atcaattctc
    54361 ttacatcttt gattcgttca aaaaaattaa tagaaccctc tctttttgca atagtgggat
    54421 ttgaagttac cccagctagc ggcaaaattt cagaccactt tttaatctca tctaaattta
    54481 atgtgtcaag cataaattcc ataaaaagaa cctctttatt ttacaaagta tgctcagtac
    54541 gtcctataat gtcatcttgg gttgccttag aaagaacatt gaagaatgca gagtatcctg
    54601 caacacgaac aattaagtct ctgtgttttt caggatgttt ctgagcgtca atcaacgtct
    54661 ctctggaaac aacattgtat tgaatatggt acccatgtaa acgattaaag aatgttcgta
    54721 acaaagcaat tagttttaat ttatcttctt ctttggctaa cgtttgagga tttactttct
    54781 gatttaagag aaccccacct acgatttcat ctgttggtaa ttttgaaaca gattttaaaa
    54841 cagatgtagg gccgtgttga tccatattat gtgatggtga acaaccctct gctaacggtg
    54901 tacccgcgtt gcgtccatct ggagttgcta atgttccacg tccctgccct acgttggctg
    54961 agatagaaga tgttcctgaa taacgaattc ctccaattgg acctcttcca taacgtgtat
    55021 taggatattt agcaatttca tcaacataaa tgtcataagc agcagtaacc aatttgtcag
    55081 cataatcatc atcattacca tacttaggtg catcatgaat caacatttct tgaatgacct
    55141 taccttcttc tccggcataa tctgtttcca gtgcatgcca aagctgactt gggcttatac
    55201 gttcttcctc aaacaccaat tttttaattg cagctaatga atccgacaaa tttgcaattc
    55261 caacttgcaa tcctgatata taatcatata ctgctccacc ttctttaagg tgttttccac
    55321 gaccaataca atcatcagtc aatgctgaac atagaatatc aggaacttct cgttccaatg
    55381 ataaatcaat agaattttca acaataacac tcattcgtgt caaatatctt agtgttttat
    55441 cccaagcatt ttctaattca gaaaagttct tcatatcctt aaaatgacca aagcttggtg
    55501 caaaccgttt acccgaagcc ggatcaattc catcattcat cgtgataagt agaaccttag
    55561 ggaagttcat ataactcata cctgtgcaac gatagcccca tttccctgga actgccgttt
    55621 caacacatcc aatggcactg taatcataag catcatcttc caatactcct tttgcaataa
    55681 aagaaggaat aataatctca tcattattaa atgcaggcat accaaaacca agtttcatca
    55741 cttcaataca ctcattcatg aaacgagcat ctaaacctgc atggtaacgt acagttagat
    55801 taggttgcgg tagatgggtt tgtgcaactg attttaatac caaataagat aatgggttaa
    55861 cagcatcctt cttatctcga gtctgtccac caattgtaac attttgatat aaaggacttc
    55921 ctgctgaaga aaatgtatgt gattgactgc gaaccttatt aattgtaatt gtcttaatcc
    55981 aaagatttgt cagacgttca acaatgctat cttctgtttc tttaccactt tctaaatcag
    56041 ccttcatata tggatacata tattgatcaa aacggccata tgaaagagag tggccattag
    56101 attcaatttg taaaatacat tgaataaacc aaactgattg aatagcttct gcaaaagtag
    56161 ttgccggttc atatgggact ctagagcaaa tatctgcaat ctcaagtaat tctttcttac
    56221 gtttaggatt tgcattttcg gctaaacttt tagcaagagc aacaaagcgc tttgcatata
    56281 ctttaatagc atcgattacg ataaatatag agtcgtaaaa atgatattta tcaatacttg
    56341 ctggatctgt taaatctaga gctacttttg ctttacgagc ccgctcttca aaacctctta
    56401 aaccaaattg caaaagtttc tgatagttaa ctgctaagtg agcatctcca gaattcatct
    56461 taccttccat accgaagaat cctgtttcca tataaactga cacttcttca ggtaataagg
    56521 caccagctct agcacgtaaa ttattatttt cccaaaacgg agcaatactt ctaagttgtt
    56581 cttttgtttc ttctgtaata tagaaaacat ctccatcacg cttttcaaaa agatccaact
    56641 cattgagaac aaattctagc gtatattccg gaaaaatagg agcatcttta ttggaagaag
    56701 cttgatttcc cgcaatcata gattcttctt caatatagat agacatattt tccaaaattt
    56761 ctttcagcat atatgcacgt tttaggacat taggttgttc cttgtatcgt tcataggcgc
    56821 gtgttgctag aactgctctc tcagcatcaa tataaggttt tttatttaaa acatcttctc
    56881 gatatttgtt catcctttca gtaaggctgc caaaatattc tgttttgatt gttgttcttg
    56941 ctacttctgt atttaccatc gtaagcacct ttctttcgaa aatattttta tttctttcga
    57001 aaatattttt atttctttcg aaaatataat accgattttt atagaaattt tcaagctttt
    57061 aactagaaaa attttaactc tctaattttt agcacaaatg tgtgagttta acagtaacac
    57121 acaaatacct ctaagattgt ttgatttcat tttggtaagc taaacgatct tgtatcttaa
    57181 agaatggaaa gtaaaccact gtagatatca ccaatactaa taactgagtc acaacacctt
    57241 gccatccacc caccaaaaat cctgatagaa tagctggtgt actccaaggc aatgttaccc
    57301 ctgagaatgg ctgcatgaaa cctgttgcaa tagctccata tactatcaca gctgcaagta
    57361 caggaacaag aatgaaaggt acaaacataa ctggattcat gacaatcgga aatccaaata
    57421 caactggctc atttacgtta aatattgctg gaaaagctgc aacttttcct aaggcttggt
    57481 attgttttga ttttgctgca aaaagcatgg caactacaag accaaacgta atccctgaac
    57541 ctgatagaat taaaaatgaa tctaaaaatt gttgagtaac aatatgtgca ccattttcta
    57601 atgatagatt accagaggct aacatagctt tattagcatc aagattagat aaaagcagag
    57661 ctgtcactac tccatttact accgattgcc catgaacacc aaaccaccac aaaaatgata
    57721 taaagaatgc aattccaata gcaccataca aagatccagt taaaccttgc aacggaactt
    57781 gaatagcaga ataaatcatt tctatgaatg ttccgccatt agtcaatgac ttcgctaaaa
    57841 tatatacaat catagaagat aagaaaatta caaatgctgg aatcattgct tcaaactgtt
    57901 tggcaatagc ttgtggaact tgttctggca tcttaataac aatttttctc tttataaaga
    57961 aggtataaat acttcctact accaaaccta taatgatagc accgataatt ccttggcctc
    58021 caaaccaaac tttactaata gcgtccccaa tcgcctcacc ttgtttaggg atataagatg
    58081 atcttagcaa aataaagaat gcagatacag atagaactcc agctggtaaa gcctctactc
    58141 cgctattctt agcataagaa taggcaattg aaaaacaaga aattagaccc ataatagcaa
    58201 aagttcctga atatacttgc ataaacggct ctgtccaatt agctccaaaa acactagcaa
    58261 tgctcttatt taatccttcg aacggcaatt gtcccataat caagaacaaa ctgccaacta
    58321 ctgtcaatgg caaaattgct aacatcccat cttttagagc tataatgcca cgcatattca
    58381 caaacttcat catcggtgca atgattttct gaacatccat ctttgacata ataaatctcc
    58441 ttttcttacc cactaatcaa agatagggcc aaatctaata cttttttccc atctaacata
    58501 ccatagtcca tcatcggaat aacagctatc ggaacatcac acttatcaca aatttctttt
    58561 gatttatcta atgtataagc aacttgtgga cccaatagtg caacatctat atttggcgca
    58621 taatccgcta atttagactg agaaaacgcc tctatttctg cctcaactcc actagattgc
    58681 gctgcaattt tcatattatt tacaagcata ccagtagaaa aacctgctgc acaaaacaaa
    58741 ccaatcttca ccattatgtt ttcctcctct atgttaataa caatgataat actctagtat
    58801 tattttttat gaagttcttt tctcaaacta ataatttctt tgattaaatt aatctccgtc
    58861 atactagtca tgagatgatc ttgtgaatga acaaagagag ctgtaatttc tgtctttgta
    58921 ccagacgctt cctgtgccaa gaattttgtt tgtagattat gagcttctaa taaggctgca
    58981 tcagctaact ggatttcttc ttcacaccgt tcacatgtac cattttttat gtaatctaac
    59041 gctttataaa tatgttgttt cgcatcacca gcatataaaa ttaaacccat gataatttga
    59101 tctggaacaa taatttccat aaattcctcc tcatttcact atgtaaaaag cttttttcat
    59161 ttgaaatttt aaaattttct tttgtaacta tagaatacaa ctacataata aagttgtcaa
    59221 tccaaaaaca acagataaac tatttttgtt tatataagca caaatgtgca atcaactaaa
    59281 aagaaaaacg ataaactgaa tcagtctatc attttcactc acctagaatc tctctaaaag
    59341 tcaaatcccc atcttcttcc aaaactttta aaattgtatt tttgtctgta atcaaatgat
    59401 ttactaaatt agcacgcaag acagaaagaa tcgaagatac tttcgtatca ccgtaagcaa
    59461 cagctaaact ttgaggaata ttttttaaat cttccaaaga gattgctatc gttctttcct
    59521 gtaagttttc atagacttct ttaccttttg aatcaaaaaa tcgacaacaa atttctccta
    59581 cagttttaac tttggtcaat tctttaaagt catcctctgt aagcatgtct aaccattgat
    59641 gctttccttt attgctaaaa tcaccaattc cgactacagc tatatctaaa tctttccaac
    59701 tatttttcaa attttcaaaa tatcttgatt gcaaaatacc atctgctaac aatttatttt
    59761 cttgcacaat cgttgcattc ataaatgtac actctccatg aaattttcta gacatttcat
    59821 aaatcagtgt attcacatgg tatttagcgt gtatgtgact aggaccacct gctagaggat
    59881 agaagtgaac atttcggaca cttttactgt gaattaaatc tactaaatta cttaaacttt
    59941 tcccccaaga aaagccaatt ttcatattat catcaattag attcctaagg acacctgctg
    60001 caacttgaga aattctttca gataaaattg ttggattatc atcaaattca tttggaataa
    60061 tttctaaact ttccagacca tatttttctt ttacataatt ttccaactta aacatattgg
    60121 tatcaaaatt ctctatttca attttaacaa ttcctgcatt ccttgcttct gttaacattc
    60181 tactaataga ggttctataa attcctaatt ttgctgctat ttgtgactga tttaagtttt
    60241 caatataata cagataagca attttagaga gcagtttatt cctatcttga ttcatacatt
    60301 taacctctta cgaaactacc ttaaccatta tcccagcatt ttctaatgta gctatatttt
    60361 gtttagaaag tttttcgtct gttattactt catagacttg acttaaagca aatcttctta
    60421 ctgtacccct tttatcaaat ttacttgagt cagttagtac aatgacttta tccgacgctg
    60481 ctgaaatata ttgaactacc tcactgcgca ttaaatcttt tcctgtaaag cccatctctt
    60541 tatcgtaacc atctgtccca acaaaagctt gatgcacatg aaaagtctgt atcatttctt
    60601 ttaataaagg tcccacagta acctgtgaat ccttctgaaa ctctccacca agaacaataa
    60661 tacgacatga atcataagct ctcacaaaat ttgctataaa aaatgaattt gttacaatcg
    60721 taacatttct tttttgcttg caaatttcct cagcaagtaa agcacaggtc gatccagatt
    60781 ctatcattat tgtttcatta tctgacacca attttactgc ttcctgaaca atttttctct
    60841 taatttcata attaattgac aaacgtacat ttaagtcatc tccactattt aatacagcat
    60901 atccatgctc tctgtgtaat aaaccttttg actctaattt atctaaatct tttctaatcg
    60961 ttactttcga tacatttaat ttttccgata atgtattaac gtcgatcttt tcatattctg
    61021 atactaattt aataatttgt tccaatcttt tcattttaca cctccgtttt attctaccaa
    61081 aataaaaagc aaaaaacaac aaattaaact ttcgttcgta attgtttttc tttcgttttt
    61141 gtgataggat agacttatga agaggaggaa ctcttatgga aatatctaaa ggaattattt
    61201 ttaatattca acacttttca attcatgacg gcccgggtat tcgtacaact gtttttttaa
    61261 aaggatgtcc tctgcgctgt ccatggtgtt ctaatcctga atctcaaaga atgaaacctg
    61321 aaaaaatgaa agatgctcaa cgagagaaat tcaccttagt cggtgaagaa aagactgtag
    61381 aagaaattat tacagaggta ttaaaagaca aagaatttta cgaagaatcc ggtggaggtt
    61441 taactttatc aggaggtgaa atatttgctc agtttgaatt tgctaaagcc atcttaaaat
    61501 cagctaaaga acatcacata cacactgcca ttgaaactac tgcctttgtt gatcatgaaa
    61561 aatttatcga tttaattcaa tatgtggatt ttatctacac agacctaaaa cattataatt
    61621 ctataaaaca taaaaaagtg actggggttt ttaatcaaat gattattaaa aacattcatt
    61681 atgctttttc tcaaaataaa actatcgttt taagaatccc agttattcct aattttaaca
    61741 atagtttaga ggatgcagaa aaattcgcta ctctatttaa ctcattaaat atcgaccaag
    61801 ttcaactact cccttttcat caatttggtg aaaacaaata tcgtttatta aatcggaaat
    61861 atgaaatgga tggaatcaac gcacttcatc ctgaagatct tattgattat caaaaggtat
    61921 ttctgaacca ccatattaat tgttatttct agttcatttc cttgaaatgc tctagctatt
    61981 tgcagataac aagcatctat aatacatact taacttttca aaaggtttag ctaaaaaatt
    62041 ttagccaaac cttttctatt ttaccttgct ctagaatttt taaactgcta tacttatcac
    62101 aaaaaaacct tccaatgagg tagcggatgt ctcattcctt taaaaaatct ctccaaaaag
    62161 aaattctcca tagaagctct atcgcagcct ttgtgacctc acgcgcattc tccgatacag
    62221 tatcaccgat ttagaaaaag aaacaaccat ttgtcaggat ttaaagatta tagaggatta
    62281 ccttatgatt cataagattc gtttcgagca cttttcctat gatattgtct gcccagaaac
    62341 tgtcgataat cagcctatcc ctaaactttt cttgcttcct ctagtagaaa atgctataaa
    62401 acatgggatg caataccgta ttgatcttca tattgatatc cacattacct tggaagcaga
    62461 ttctctaact tttttagtca aggataatgc tggaggactc accaaacaag agcgattcgc
    62521 tattttagac tctttagaaa gccctcatac ccagcatggc atcatgaaca gctacaaaca
    62581 attgagcaat ttcttttctg atgtccagct agatttagga gtcaatcgcc aaggagaaac
    62641 ttgggtcaaa tttgtaacga aagactaact catgtttaag ctcattattg tagaagatga
    62701 acacctcatc cgaaaatggc tagagattgc cgtagactac tctgccttag gcatccaagt
    62761 cgtaggaact gccagtcacg gtcaagaagg aatgaaactc atccaagaaa aagaaactca
    62821 tatttgtctt aacagacatc acaatgccaa ttatggatgc ttttatgatg ttcaaagcca
    62881 ctcgtactct ttcttatgaa aaagttatct tatcaggtta taacgatttt caaaatgcca
    62941 aaaagccatg caatatggag cagttgattt cttatccaag ccaattgata ccaaggaatt
    63001 gacagaatgt cttcaaaaaa ttgttttgcg attacaaatt agcacatctc aagaaactcc
    63061 ttttttagaa gaatatcaaa ctttactcac ctctatccaa caggttgata cacaaaacca
    63121 aatcattcaa caaattatct cctttgtcca caagcactat gcagagcatt actattgctg
    63181 aagctttaaa ctataacgaa agctatctat ataaggttat caaagatgac tctaaatgaa
    63241 tatatcttac aatatcgcct gaaacaagct atagataaga tggctgaatc tcccaactcc
    63301 cctttaagcg ctatctctga ccaagttgga ttttcagact ataaatattt tgccaaagta
    63361 tttaaaaagc atctccatat ttccccaaag gaattgaaat tactcggaag aatagtaaaa
    63421 taggctattc ttctttttgt agagaatttt actctaatat agtgaattga aataagatgt
    63481 gaacatctct atcaggaaag tcaaattaat ttatagaaat attttagcag tcaaagtgta
    63541 ctgttataga ttcaatacac tatagaatag aattgtaggt tttaaaaacg cttacattgt
    63601 tttaaaataa acttaaataa cacaacggag gtatccatca tgaaaaagaa atggatgtat
    63661 tatgctgctt gttcttctaa tgaatctgcc gatgacagtt catctgataa aggagacggt
    63721 ggttcgctag tcgtttattg accaaactca gaaggcttaa ttggagcaac tattcctgcc
    63781 tttgaagaaa aatatggtat caaaatagaa ctgattcaag ctggtactgg agaacttttc
    63841 aaaaaactag agtcagaaaa agaagttcct gtagctgatg ttatctttgg tggttcttat
    63901 acacaatatg ctacccacgg agaactcttt gaaaactata tttcaaaaga aaatgataat
    63961 gttatcaaag aatatcaaaa cacaactggc ttctctactc cttatacact agatggtagt
    64021 gttttaatcg tccaccctga tttaactaaa ggcatgaaca tcgaaggata tagcgacctt
    64081 ctcaaacctg aactaaaagg aaaaatcgca actgctgacc cagcaaactc ttctagcgcc
    64141 tttgctcaat taacaaatat gctacaagct caaggtggtt acaaagatga taaggcttgg
    64201 tcttatgtaa aagatctttt cacacttatt gatggtatag taaaatgaaa taagaacagg
    64261 acaaattaat caggacagtc aaatcgattt ctaacaatgt tttagaagta gaggtgtact
    64321 attctagttt caatacacta taaaatcggt ttaagttcat ctggtgtcta taaagcagtc
    64381 gttgatggag aaatggctgt tggtctctct tatgaggatc cagcagttaa actcttaaat
    64441 gacggagcta acattaaagt agtctatcca aaagaaggaa ccgtcttcct acctgctagt
    64501 gctgctatcg ttaaaaaagc taaaaatatg gaaaatgcca agaaatttat cgattttatt
    64561 atctctcaag aagtacaaga tacacttggt acaaccacta ctaaccgtcc tgttcgtaaa
    64621 aatgctaaaa caagcgaaaa catgaaacca attgacaaaa tcaaaacact cactgaagat
    64681 tatgattatg tcatcaagaa taaatcagat atcgttaaga aatacaacga agtctttaca
    64741 gatatccaat ctaaacagta aaagaggttc actatgagtg agatcgaaat tattaacgcc
    64801 aaaaaaatct accacgatgt ccctgttatt gagaatttga acattacaat tccaaaagga
    64861 agtctcttta cccttcttgg agcttcagga tgtgggaaaa cgacccttct tcgtatgatt
    64921 gcaggtttca acagtatcaa agatggagaa ttttacttcg atgatacaaa aatcaataat
    64981 atggaaccca gcaaacgcaa tatcgggctg gttttccaaa actacgctat tttcccacat
    65041 ttgactgtcc gagacaacgt tgcttttggt cttatgcaaa agaaggttcc aaaagaagaa
    65101 ttgattcaac agaccaacaa gtatcttgaa ctcatgcaaa ttgctcaata tgcggattga
    65161 aagcccgata aactcagtgg tggacaacaa caacgtgtca ccttggcatg cgccttagcg
    65221 gttaatccaa gtgttctcct catggacgag ccacttagta atctggaggc caaacttcgc
    65281 ttggatatgc gtcaagccat ccgagcaatc caacacgaag tgggaattac aactgtttat
    65341 gtaacccacg accaagaaga agccatggct atttcagacc aaattgctgc tatgaaagat
    65401 ggggtgatcc aacaaatcgg ccgaccaaaa gaactctatc ataaaccagc taatgagttt
    65461 gtggcaacct ttatcggatg cacaaatatt atccctacta atcttgaaaa acggagcgac
    65521 ggcgcttata tcgtcttttc agatggctat gcccttcgaa tgccagctct tgatcaggtt
    65581 gaggagcaag ctattcatgt aagcattcgt cccgaagagt ttatcaaaga tgaatctgga
    65641 gatattgaag gaactattag cgatagcgtc tatcttggac taaatacgga gtatttcatt
    65701 gagacaggtt ttgcctcaaa aattcaagtt agtgaagaat caacttttga agaagaacta
    65761 caaaaaggca atcgtattcg tctacgaatc aatacgcaaa aattaaacat cttttctgca
    65821 gatggttccc aaaacctgat aaaaggagtc aaccatggaa tgtaaaaaac taaatatttg
    65881 gacaacctcc tctttcttca tctttcttac ctatcttgtc tttctcgttt atcctatcgt
    65941 taccgtgctc aagcaagcac ttatacatga aggacaattc tcactagcta attttgtcac
    66001 tttctttagt aaagtctact actctgagac actagtcaac agtttcaagg tttccattac
    66061 cgctactgtc acttccttag ttgtaggaac cctattagct tatctcttct ctatgtatga
    66121 cttcaagggg aagaaatttc tacaaatatt gattatcatt gcttccatgt cagctccttt
    66181 cgtaggagcc tactcctggg ttctcttgct aggacgaaat ggggtcatca ctaaattttt
    66241 gacaaatgcc cttcatcttc cagctatcga tatttatgga ttcaaaggaa ttgtacttgt
    66301 ctttacactg caactattcc cactggtatt tctatatgtt gctggaacaa tgaacagtat
    66361 tgacaattct ctacttgaag cagctgaaag catggggtcc ttcggattta aacctatcgt
    66421 aacggttgtt ttacctctcc tagttccaac cttactagca gctccttgct tgtatttatg
    66481 agagcattct cagactttgg aacgcctatg ttgattggcg aaggatatcg gactttccct
    66541 gtcctgattt atacccaatt tattagcgag gttggaggaa attctgcttt tgcaattatg
    66601 gcgattatca ttgccttggc aattttcctt atccaaaaac acattgcaaa ccgctacagt
    66661 ttcagcatga atctgctcca tccaattgag cctaaaaaaa ctacaaaagg aaaaatggct
    66721 gccatttatg caacagtcta cggaattatc tttatctctg ttttacctca aatctactta
    66781 atttatacct ctttcctaaa aacatcaggt atggtatttg ttaaaggtta ttctccaaac
    66841 agttacaagg tagctttcaa tcgtatggga tctgctattt tcaataccat tcgtatccct
    66901 ttgattgcct tagttctagt tgttctattt gcgacattta tctcctacct agccgttaga
    66961 aaacggaatt tgtttacaaa cttaattgac agcctcagta tggtacctta tattgtacca
    67021 ggaaccgttc tagggattgc cttcatttct ctggtctatt tggaagtgga tttcttatga
    67081 ttacagggac tgctttcatc ttgattatgt ctctatctgt cagaagatta ccgtatacta
    67141 ttcgctcatc tgttgctagc ttacaacaaa tagcaccaag tattgaagaa gctgctgaaa
    67201 gcttaggaag tagtcgtctc aatacctttg ctaagattac aactccaatg atgctatctg
    67261 gtatcatttc tggagccatc ttatcttggg tcacaatgat ttcaaaactc tctacttcta
    67321 tcctcctcta caatgtcaaa acaagaacaa tgactgtagc tatttataca gaggttctca
    67381 gaggaaatta cggtgtagcc gcagccttgt caactatcct gactgttcta acagtaggtt
    67441 ccttgctctt gtttatgaaa atctctaaaa gcaatagcat tacactttag ttttccacat
    67501 caaaaacagc cgaaaggagt accctcggct gttttttctt atcttgatat ccttatcaaa
    67561 tccctagctc atggcaagca agtctagact gattaaatag agccttcttc catcttctca
    67621 cgtcctagct ctcggtaact acggtcaccg acaacttcaa ccctaaactg accgtcctca
    67681 tattcaagaa tcgtcacgct accattatct agaccatgcg gatgcatgcc attaatcaga
    67741 taaacaatgg ttccaatagt cattccatgg ctgacaacaa gggcgttacc tccaccttga
    67801 tcttccattt cttttgcaat tatttcaaag ccttccttga ttcggccact gagtttttcc
    67861 cagccttcag cccaaccagc tgtatcgacc tctaccaagc cctcagccag ttcagcataa
    67921 gacaattggt gaacgtggtc cacattaaag atacgaggaa taatgcccat gaaaagatcg
    67981 ccatcatagg ctccatcaaa actaccgaaa caccattctc tgatacgctt gtccatgcga
    68041 taagggattt tcccctgcaa gccaagctct tcaaggataa ttcccatggt ctgaatggta
    68101 cgaccagaat cactcgaata agcgcgctca aactgtagat cagattctcg caaaccgatt
    68161 cctaactctt gaatccctcg ttcaccttca gcagttaagg gagtatcgct ccaaccttgc
    68221 gcgcgaccaa tcgtgttaaa catggtcttg ccatgacgta ccaaatacaa tcgtactttt
    68281 accattttcc gtcctccgtt tgcttctatt atatcatgaa tgataaaata aaagccaccc
    68341 atacaggcga cttttgaagg agattattat gaaaaagttt aggagttcat taaataaaga
    68401 tattagatga aaatcaaatt caaactaatt cagtgttatc tgtttcaaat aatattagga
    68461 ggtctttatt taatgattat agtatacaca tctaatctta aatagaactt aaaatttctc
    68521 ctattttctt aatttttaaa actatgaatt ggtgctggga tttgtccacc gcgagagatg
    68581 aagtcgacag acgaagcccc attaaccttc ataacgggtg cagttcctaa tagaccacca
    68641 aactcaatca tatcgccttc tcttcctttg ggaatgatac gaacagctgt tgttttcatg
    68701 ttgataacac cgattgctgc ttcatccgca atcatagccg caatagtttc agcaggcgta
    68761 tcttctggga tggcaatcat atccaatcca acagaacaga tagccgtcat agcttctagt
    68821 ttttctaaat taagagagcc attttgcact gcagcaatca ttccttcatc ctcagaaaca
    68881 gggataaagg caccagatag accaccgacc tggttacagg ccatcactcc acccttttta
    68941 acttggtcgt tcaagagggc caaggcagct gtcgttccat gcgtgccaac tgtttctagc
    69001 cccatttcct caaggacacg tgccacagag tctccaaccg caggggttgg tgccaaactc
    69061 aagtccacaa taccaaactc cacacccagt ctctcactgg ccatttgacc aaccaattga
    69121 ccgatacgag tgattttaaa ggcagttttc ttaactgttt cggctactac atcaaagctc
    69181 tgtccacgaa ctttttccaa agcacgtttc acaacaccag gaccagaaac tccgacattg
    69241 atgataacat ctgcttcccc aacaccatga aaggcacccg ccataaatgg attgtcctca
    69301 acagcattag cgaatacaac caacttggcc actcccatat ctgaaagatt tgctgtttcc
    69361 ttgataattc gtcccatatc tgccacagcc gtcatattaa taccagactt ggttgagccg
    69421 atattgactg acgagcagac cttatccgtc tcagccaaag cgcgaggaat ggaattgatg
    69481 agaatctcat ctcccttttg ataacctttt tgtactaagg cagaaaaacc accaataaag
    69541 tccacaccaa tctctttcgc agccttatca agcgcttttg ccagaaccac gtagtccgtc
    69601 gcatctgtcg ctgccccaat cagagaaata ggtgtcaccg atacacgctt attaacgata
    69661 ggaattccca actcagccgc aatttcatca ccaacagcta ctaaattagc cgcctttgtc
    69721 gtaatttttt gatagatttt ctccgcagca cgattgatat ttggatcgat acagtccaaa
    69781 agagaaatcc ccatggtaat ggttctaata tcgaagtttt gctcctcaat catggcgatg
    69841 gtttcagtaa cttgtctaat atccatgatg acctcctaga tattatacat agcttcgaaa
    69901 atcgctgcac tctgaatatt gatttttaca ttcaaagttt gcccaaaagc ttcaaattca
    69961 ttacgaagat aggtaaaatc ttgcttttca tcactagata caacagccat catcgtaaaa
    70021 tattcatcca atacagtttg agagatatcg tcaatattca atcctaattc tgcaatttta
    70081 ccagaaacac ctgcaacaat tccagattta tctttaccaa caacagttat aatcgctttc
    70141 ataagtaaac tccaattctt cttaaaataa gaaaccttaa cattaaacag gattcttttc
    70201 aaatagtata gcataattct aacgaaaata ctcaaaaacg cctgcttacg aagttgttct
    70261 taagaaaaaa acaatttcgt aaacaagcgt ctactatccc aacttatgat gagtgttccc
    70321 gctaggaccg aaatcctagc ggtagaccag agctagacta agagcacaag actccatcat
    70381 cataacactc aacaaaattg atgattttat actaattcga tgatcgccat tggcgctgca
    70441 tcaccacgac gtggttcagt tttaaggata cgagtgtatc caccgttacg ttcagcataa
    70501 cgaggtgcga tttctgagaa caatttttga agtgctgtag tagaagtgta cttatcagtt
    70561 gcttcatcat agttttcaga tgcgatttca ttacgtacga aagcagctgc ttgacgacgt
    70621 gcatgcaaat caccacgttt acctagagta atcatttttt caacagtttt acggatttct
    70681 ttagcacgag cttcagttgt cacgattgat tcgttgatca aaaggtcagt tgtcaaatcg
    70741 cgaagcattg ctttacgttg tgagctagtg cgtcctagtt tacggtaagc catgtattcc
    70801 tcctttattt atcttttaat ccaagaccca aatcaatgag tttgagtttc acttcttcca
    70861 aactcttgcg tccaagattt cgtactttca tcatctctgc ttcagatttt tctgtcaaat
    70921 catgcacagt attgataccg gcacgtttta aacagttgta tgaacgcaca gacaagtcca
    70981 gttcctcaat cgtacgatct aaaatacggt cgtcagattc agtatcagct tctttcatca
    71041 cttcagttga cttagcaatc tcagtaagat ttgtaaacaa atcaagatgt tctgtcaaaa
    71101 tacgtgctga aagccctaaa gcatcttctg gaataattgt tccatttgtc aagatttcaa
    71161 gggttaattt gtcgaaacca tcattgctac ctacacgagc aggttccact tgatagttga
    71221 cttttgtaac tggtgtataa atagaatcta cagcaagtgt tccaactggt gcattatcct
    71281 ttttattttc atcagcaggt acatatccac gaccactgtt aacagtcata gtcgctttta
    71341 gagaagaacc ttcaccgatt gtaaagagat aatgatctgg atttacaatt tcaatatcgc
    71401 tatctgtcaa aatgtcacca gctgttactt cagcaggacc ttcaacatcc agttcgatga
    71461 ttttttcgtc ttcaacgtac gatttcactg caattccttt aatgttcaga atgatttgca
    71521 tcacgtcttc acgaacacct ggaactgtgt caaactcatg taacacacca tcaatgttga
    71581 tagatgtcac agctgctcct ggtagagaag ctagaagtac acgacgaaga gagttaccaa
    71641 gagttgtacc gtagccacgt tcaagtggtt cgattacaaa cttgccataa tctttatttt
    71701 catcaatttt tgttatattt ggtttttcaa actcgatcat ttagttactc cctcttaaac
    71761 gaaaagcagt gtaatgcgat gattatacac ggcgacgttt tggaggacga gcaccattgt
    71821 gtggcactgg agtcacatca cgaattgctg ttacttcaag accagcggca gcaagcgcac
    71881 gaatagctga ctcacgacca gaacctggac cttttacagt aacttcaact gatttaagac
    71941 cgtgttcttg tgcagattta gcagcagctt cagaagccat ttgagcagcg aatggtgtag
    72001 atttacgaga acctttgaaa ccaagagcac cagctgatga ccaagcaatt gcattaccat
    72061 gcacatcagt aatcataaca atagtgttat taaatgtagc gtgaatatga gcaataccag
    72121 attcgatatt ctttttcaca cgacgtttac gtgttggttt agccaagact tttacctcct
    72181 atattatttt ttcttaccag caatcgcaac agctttacct ttacgagtgc gagcgttgtt
    72241 tttagtattt tgtccacgga caggaagtcc acgacggtga cggataccac ggtatgaacc
    72301 gatttccatc aaacgtttga tgttcaagtt tacttcacga cgaaggtcac cttcaacttt
    72361 gattgcatcc acttcacgac ggatagcatc ttcttgatct gatgtaagat cacgtacacg
    72421 aacatcttct gagattccag cagcagccaa aattttctta gatgttgcaa gtccgatacc
    72481 ataaacataa gtcaatgaga ttactacgcg tttgtcattt ggaatatcaa ctccagcaat
    72541 acgagccatg ttttctcctt tctatcttat ccttgacgtt gtttgtgttt tggatttgct
    72601 gggcaaatta ccataacacg accattacga cgaataactt tacagtattc gcaaattggt
    72661 ttgaccgatg gtcttacttt catttcttat ccctccaagt ttttcgatta tttaaagcgg
    72721 taagtgatac gtccacgtgt caagtcatat ggactcattt cgacagtaac acgatctccc
    72781 gctaaaatac gaatatagtt tttacgaatt ttaccagaaa ctgttgctaa aatctgatgt
    72841 ccattttcaa gttcaaccgt aaacattgca ttcggcattg tatcaactac tttgccttca
    72901 acttcaatca catcgtcttt tgccacgcaa aagcacctcc ataaatttcg attcgatgcc
    72961 tctagacaca gagacaacaa ttataagtca gactatctca gtataacatt tgtagcggat
    73021 ttttgcaagt gtgaaaaacg ctttatttca aatttgtcaa tactttttca atatctgaga
    73081 agacatcatt gatatcttga ttaccttcga tgtcatgaac caaacctttg gcacggtagt
    73141 gagcaatgat tggttctcct tgagcaatat taacatccaa acgacgtttt actgtctcag
    73201 gcttatcatc ttcacgttgg tagtaatctt cttctttata gtcaactggt gggttaaaga
    73261 ccttgtggaa agtttctcca gttacgcagt ggatgatacg gccactcaaa cgttccaaga
    73321 ggctgtcagg gttcacttca atattgataa taccttctag ttcaatgcca agttcagcca
    73381 atgttttgtc caaggcatga gcttgttcaa ttgtacgtgg gtaaccatcc aataagaatc
    73441 ctgtttcttt aatatcatct tgtgaaaggc gttcttttac gattccattt gtaacttcgt
    73501 caggaaccaa ttcacccttg tcaatatatg acttagcaag aacacccatt tcagtttgat
    73561 ttgccattgc agcgcggaac atatcacctg ttgagatatg tgcaacatgg aattgttcta
    73621 cgatttttgc tgcttgagtt cccttacctg caccaggtaa gcccataatc aaaagattca
    73681 tgatttgatc tccttatttt atttttaaat agaagcaaaa agtcttttca cccctattta
    73741 aaaacaaaat agaagagggg agatccaact cttacaaatg tcagagttta aacctccact
    73801 ccctcagtat ttactgattc agtaaatact tttattctgt tctgtccatg aaaccaacat
    73861 acttacgttt caataggtaa ccttccaatt gcttgattcc ttcgatacct gtagagataa
    73921 tgatcaagag acttgttcca ccaaaggcaa caacatcaga aagaccaaat acatctttag
    73981 ctgcaatcgg taaaatggaa atcacaccaa ggaagaggga accaacagtt gcaagacgac
    74041 gaagaagttt agacatatat tcttctgtac ctttaccagg acgaactcca tggatatagg
    74101 caccactctt ttgtaggctc tctgctgctt tttcaggatt aatctgtaca aacgtataga
    74161 agaatgtaaa gagaataatc aacaaagcat acatggcaat accagttgga gaagtagttg
    74221 ccaacatctc ttgtgctacc cttacccaag cccaatcatg acctgtggca ctcaaaaact
    74281 gaagaatagc cgcaggcgct gcagtaatcg aactggcaaa gataacaggg ataactccag
    74341 caggatttac ctttaacgga aggtaagagc tagatggagc accttgtgca accttagtat
    74401 attggattgg aattttgtat tctgcttgtt gaacataagt tgtaaagtaa ataatcaaca
    74461 atacagtaat aatcaaaatg attacgaaaa tgatagatga agtgatacgg ctacttggga
    74521 cgttcacaaa gtagtccaca tagatgccct gaatcatctc tggaattgaa gaaacaatcc
    74581 cggcaaagat aatcatggaa acaccgtttc cgtatccctt atctgtaatt tgctcaccca
    74641 accaagtgac aatcatacta ccagctgtta agatgatacc aatcgtcaga aaaacttgtg
    74701 gagttaaagc agttttaatc aattgagctc cagccaaggt attaaaacca gctgtaatcc
    74761 cgatagattg cacaaaagcg agaactagag caatataacg agtagcttga ttcaattttc
    74821 ttcgacctac ttccccttgt ttaccccact ctacaaactt gggtaaaata tccatttgca
    74881 agagttggac aacaatagaa gcggtgatat agggactaac tcctaaggca aaaatcgaaa
    74941 agttttttag ggcattcccc gacaccaagc tcaacatgtt taagaaggat aatccactta
    75001 aagcattcaa gctattggca ttcacaccag gaactgtaat gctagttccg atacgaaaga
    75061 ccaaaacgat aaaaattgta aataaaattt ttgatcgaac ctgcttgact ttaagagctt
    75121 ctcttaataa tttaaaaaac ataggtcacc tctcttagat gacttctact gaaccacctt
    75181 tagcagtgat agcttcttca gctgatttag agaatttagc tgctttcaca gtcaatttct
    75241 tagtcaactc accgttacca agaattttaa tacctgactt ttcagcttta acaattcctg
    75301 cttcgataag aacaactgga gttacttcag caccatcttc aaagacgttc aattggtcaa
    75361 ggttcacaat tgcgtattct ttagcgttga tgttagtgaa tccacgtttt ggaagacgac
    75421 ggaacaatgg agtttgtcca ccttcaaaac caaggcgaac tccgccaccg ctacgagctt
    75481 tttgaccttt ttgaccacga ccagatgttt taccgttacc tgatgaagta ccacgaccaa
    75541 cgcggttacg tactttacga gaaccttctg caggtttcaa ttcatgaagt ttcattttta
    75601 ttttctcctc ttttgtaaaa tgctagcgcc gataagggag aaaaggttgt ctcccccatc
    75661 aactcgccta tacgatgtca tcatagatga ctatatctag ttttagggga tggtacagtg
    75721 cacatcccct aaaacttcat tagtttactt cttcaactgt tactaagtga gatactgctg
    75781 tgatcatacc acggatagca gcgttatctt ctttaataac agagctgttc aatttgccaa
    75841 gtccaagtgc tacaacagtt ttacgttgtg atggaatgcg tccgattgga gacttagtca
    75901 aagtaatttt aatttgagcc attttatccc ctttcttatg ccaaatcaga aactgaaata
    75961 ccacgaaggg cagcaatttc ttcagcgcgt ttcaattgtt tcaaaccttc aacagttgca
    76021 cgaacaatgt tgattggagt gttagaacca agtgatttag atgtaatatc tgccacacct
    76081 gccaattcca caacggcacg aactgcacca ccagcggcaa ctccagaacc ttctacagca
    76141 ggtttcaaca atactttagc tccaccgaat tctgaaagaa cttcgtgtgg gattgttgtt
    76201 ccaaccatag gaacttcgat caagtttttc ttagcatcat ctactgcttt acggattgct
    76261 tctggaactt cttgagcttt accagtacca aatcctacgc gaccattgtg gtcaccaaca
    76321 acaacaagag ctgcgaaacg aagacgacgt ccacctttaa caacttttgt aacacggttg
    76381 acagcaacta cgcgttcttc taattcaact gcattgtctt taaatgccat tttctagtgt
    76441 cctcctatta gaatttcaat ccgttttcac gagctgcatc agccaaagct ttcacacgtc
    76501 cgtgatatag atatccaccg cggtcgaaca ccacttctga aataccttta gcgtttgcac
    76561 gttctgcaac gagtttaccg acagcaacgg cttgttcagt tttagttcct tttgaaactt
    76621 ctttatcaag agttgaagca cttgcgagcg ttacacccgc tacgtcatca atcacttgag
    76681 cgtagatgcc tgtattagaa cggaatacgt tcaaacgtgg gcgatcagca gttccagaga
    76741 gttttccgcg aacgcgacgg tggcgttttt ggcggagttt gtttttatct ggttttgaaa
    76801 tcacagtttt cacctcttta gttttaaatc gtgtgctatg cacaaagttg gaaaataggt
    76861 tggtggttga tgatcaacca ctcaacatta tttacctgtt ttaccttctt tacggcgaac
    76921 gaattcacca acgtaacgga tacctttacc tttatatggt tctggtgaac gaaggctacg
    76981 tacgtaagca gctgtttgac caactacttc ttttgaaatt ccgctaacaa cgattgttgt
    77041 tgggtttgga agttcaaaag taattccttc tggagcttca acttcgtctg gatgagattt
    77101 accaacagcc aaaacaagtt tagatccttg aagctgtgca cggtaaccaa ccccacgcat
    77161 ttcaagttct ttcttgaatc cttctgatac accaacaacc atgttgttca aaagggcacg
    77221 agtagttccg tggatagttt tcatttcttt tgaatcgttt ggacggtgaa gagttatttc
    77281 agtaccttcc acacggattt caatatcttt tgagaactca cgagtaagtt ctcctttagg
    77341 tccttttaca gttacaacgt tgtcattgtt agcgagttca acaccagcag gcaacacgat
    77401 aactttatta ccaatacgtg acatgtttat tttctcctgt taaattgtca ggccagaacg
    77461 gccagttttc acggggttca gatacttatt tagttcaaga gctgaactga acacgctcta
    77521 agaactgtgc aaaatagata agttggcttg tttgtaaaca aacttctcca acttcctaat
    77581 tttgctttgt tctttacgag ctttgtatct tgattttacc aaacgtaagc gataacctca
    77641 ccaccaacat tcttttggcg tgcttcttta tcagtaagca aaccttcaga agttgaaagg
    77701 atggcaattc caagtccgtt aagaactttt ggaaggtctt cacgtttttt gtagacacga
    77761 agtcctggtt tagaaacacg tttcaagtta gtgataactt tctcaccatt tggtccgtat
    77821 ttaagaaata cacggatgac gccttgtttg tcatcttcaa tgatttcaac gttttttaca
    77881 aaaccttcgc gtttaaggat ttcagcaatc ccttttttga tgtttgatgc aggtacttca
    77941 agtacttcgt gtttagcttg gttagcatta cgaatacgag ttaggaagtc tgcgattggg
    78001 tcagtcataa ccattttgtt tttctcctct tactagtagt ttgcaagttg cacttgctag
    78061 ttaatacatg atacaaagag cgtaacagta cgagcaaaaa tagacaattt aatgcagaag
    78121 caatgctcca aagcaaattg gtcttttttg ccaaagctgt agctcgtgtt caaattggca
    78181 agcccaattg aacccgggct aaactctgtg tgaaaaagat aaactttcct agaaacttta
    78241 gtttcttcgt caagtttcct atttttactt ggagttttga cgctcttgat atcttaaatt
    78301 accaagatgc ttttgttaca ccaggaattt gacctttatg cgcaagttcg cgaaaagcga
    78361 tacgactcag accaaatttg cggtaaactg aatgtgggcg ccccgtaact ctacaacgat
    78421 tatgtaaacg agtcggtgag gcgttgcgag gtaatttaga taaaccttcg tagtcccctg
    78481 ccgcctttaa tgcagcacgt ttttcagcat aacggtcaac aattttttgg cgtttagcct
    78541 ctctagctac cattgatttt ttagccatta gatttacctc ctatattatt ttgcaaaagg
    78601 cattccaagg cctgtaagca atgcacgtga ctcttcgtca gtgttagcag ttgttacgat
    78661 aacgatgtca agaccacgag ttttgtcaac gtcatcgaag ttgatttctg ggaagattaa
    78721 ttgttctttc acaccaagtg tgtagttccc gcgtccatca aatgattttg ttggaacacc
    78781 gtggaagtca cgtacacgtg gaagtgaaac tgataccaat ttatccaaga attcgtacat
    78841 acgttcacca cgaagggtaa cttttgcacc gatcgcaaca ccttcacgaa gacggaagcc
    78901 ggcgattgat tttttagctt tagtgataag tggtttttga cctgagataa gtgccaattc
    78961 ttcagcagct ttttcaaggc ttttagcgtt tgatacagct tcaccaacac ccatgttcaa
    79021 aacaatctta tctactttag gcacagccat cactgatgag tagttgaatt gttctgtcaa
    79081 agcaggaact acttcattaa gatatttttc ttttaaacga tttgccatta tacttctcct
    79141 ttccttcgtg attaatcaag cacttcgcct gattttttgt tgtagcgaac ttttttaccg
    79201 tctacaaatt tgtaaccaac acgaccagct acaccatttt tgtccaaaac ttgaacattt
    79261 gatacgtgga tagctgcttc tttctcgatg ataccacctt gaggaagctc gttagttgga
    79321 cgttggtgtt tcttaacaat gttaacacct tcaacgataa ctttgtttac ttttggaagg
    79381 gcagtaagga caacagcttc tgttccctta tctttaccag cgattacgcg aactttgtcg
    79441 ccttttttta caaacattag gtttctcctt gatttttctt acgcccataa gggcacccta
    79501 gcttgaagct aggggactag tttgttccta aaaattaaag tacttctgga gcaagtgaca
    79561 cgatcttcat gaagccacct tcacgcaatt cacgtgcaac tgggccaaag atacgtgttc
    79621 cgcgaggagt tttgtcttca cggatgataa ctgctgcgtt ttcgtcaaat ttgatgtatg
    79681 aaccatcagc acgacgagca cctgatttag tacgaacgat aactgcttta acaacgtcac
    79741 cttttttaac cgcaccacca ggagtagctt gttttacaga tgccacgata acatcaccga
    79801 tgtttgcaaa tttacgtcct gaaccaccaa gaactttgat agtcaagatt tcgcgagcac
    79861 cgctgttgtc tgcgactttc aaacgagttt ctgtttgaat catttcagtt ttctcctttc
    79921 aggtttgatt agatgatgac cgcttcttca acaacttcta caagacggaa acgttttgta
    79981 gctgaaagcg ggcgagtttc catgatacgt acgatatcgc cttctttggc aacattgttt
    80041 tcatcatgag ctttgtattt tttagagtag ttaatacgtt taccatagac tgggtggtta
    80101 cgttttgttt caactacaac tgtgattgtc ttgtccattt tgtcagatac aacacgtcca
    80161 acaagaactt tacgattatt gcgttccatt gaaatttctc cttccctagt ctattatttc
    80221 gcttcagatt gaactgtttt gatacgagcg atttgttttt taacttcttt caagcgagct
    80281 gtttgttcca attgaccagt agcagcttgg aaacgaagtt caaacaattc ttttttcaat
    80341 tcgttttcgc gcttcgcgag ttcttcttga gaaagaccac gaagttcttt aacaaattct
    80401 tttacttcat taagtttcat gccttctcct tattctgctt cacgttttac gaatttacat
    80461 ttaactggca atttgtggct agcaagtcga agcgcttcac gtgcaatctc ttcagataca
    80521 ccagcgattt cgaacatcac tttaccacgt ttaactggtg ctacccaacc ttcaggtgcc
    80581 cctttaccag atcccatacg cacaccgata gctttagcag tgtatgattt gtgtgggaag
    80641 attttaatcc aaactttacc accacgtttc atgtaacgag tcatggcgat acgagcagct
    80701 tcgatttggc ggttagtgat ccagtggcta gttgtagctt gaagaccgta ttcaccgaat
    80761 gctacttctt ttccaccttt tgcttcaccg cgcatttttc cacggaactc acgacggtgt
    80821 ttaacacgtt taggtactaa cattggttat ttacctcctt tagtgttttt acgagctgga
    80881 agaacttcac cacggtagat ccatacttta acaccaagtt taccgtatgt agtatctgct
    80941 tcttcccaag cgtaatcgat atctgcacga agtgtgtgaa gcggaacagt tccttcagag
    81001 tatccttcag cacgggcgat atctgcaccg ttcaaacgac ctgatacttg agttttgatt
    81061 cctttagctc cagcacgcat tgcacgttgg attgcttgtt tttgtgcacg acggaaagca
    81121 acacgttgct ccaattgacg agcaattcct tcacctacaa ggtgagcatc caaatcaggt
    81181 tgtttgattt cgatgatgtt gatgtgtact tgttttccag tcaatttgtt aagttttgca
    81241 cggagtgcat caacgttagc accaccttta ccgataacca tacctggttt agcagtgtga
    81301 agtgaaacgt taactttgtt tactgcgcgt tcgatttcaa tagttgaaac tgctgcgtca
    81361 gcaagttctt tttgaacgaa tttacggatt gcaagatctt catgaaggta atccgcgtat
    81421 tctttttcag cataccattt ggcatcccaa tcacggatga tgccgacacg cataccaatt
    81481 ggatgtactt tttgacccac gattttacct ccttattttt ctgcaacagc tacagtgatg
    81541 tgagctgtac gtttgttgat tggtgaagct gaacctttcg cacgtggacg gaaacgtttc
    81601 atagttggtc cttcgtttgc gaatgcttca gatactacca agttagcttt atccaaacca
    81661 aagttgtttt cagcgttagc tacagctgag ttcaaaactt tcaagatgat ttcagcagct
    81721 ttgtttggag tgaatgtcaa gattgcgatt gcatcggcta cgcttttacc acggatgtta
    81781 tcaagaacaa gacgtgattt acgaggtgaa acacgtactg tacgagccat tgctttagct
    81841 gaagtaattt ctgccattta tgttctcctt attttctacg tgttttcttg tcgtctgcag
    81901 cgtgaccttt gtaagtacga gttggtgcaa attcaccaag tttgtggcct accatgtctt
    81961 cttggatgta aacaggtacg tgtttacgtc cgtcataaac tgcaatagtg taaccaatga
    82021 aacttgggaa gatcgttgaa cgacgtgacc aagttttaat aacttttttc ttttcgtcgt
    82081 tagcttgagc ttcaactttt ttcatcaaat gctcatcgac gaaaggtcct tttttaagac
    82141 tgcgtcccat ttttatattt tctcctttaa atgttgtacc acagcggctt gcactcctat
    82201 ggagcgctac cgagctggcg gatttactag ttgcttaagc gactagttta atattatttc
    82261 tcgttgcgac gacgaacgat aagtttgtca gatttcgctt tcttgttacg agttttaaga
    82321 ccaagagcag gtttgcccca tggagtagat ggtgctttac gaccaactgg tgctttacct
    82381 tcaccaccac cgtgtgggtg atcgttaggg ttcattacag aaccacgaac tgttgggcgg
    82441 atacctttcc aacggctacg tcctgcttta ccaaggttta caagtccatg ttgttcgttt
    82501 ccgacaacac caactgtagc acggcaagtt ccaagaatca tacgaacttc acctgattga
    82561 agacgaacaa gaacatattt accttcagaa cccaatactt gagcagatgc accagcagca
    82621 cgtaccaatt caccaccacg acctggtttc aactcgatgt tgtgaatcaa agtaccaact
    82681 gggatgttag caagtggaag agcgtttccg actttgatat ctgcttctgg acctgaaacg
    82741 atacgttgac ctacttcaag accttttgga gcgatgatgt atgctttcac accgtcagtg
    82801 tagtgtacaa gagcgatgtt tgcagaacgg tttggatcgt actcgattgt tttaacaact
    82861 gcttcaacgt tgtctttatt acgtttgaag tcaaccaaac ggtagaaacg tttgtgtcca
    82921 ccaccttggt gacgaactgt gatacgaccg ttgttgttac gaccagcctt gctcttcaat
    82981 gcaacaagca atgatttttc aggagtgctt gttgtgattt cagcgaaatc caaagaagtc
    83041 atattacggc gaccgtttgt tgttggttta taaacacgaa ttcccacgat atttcctcct
    83101 tagattattc agcttcagca gcaaacaact cgattgcttt agaatcagct gtaagtgtga
    83161 tgatagcttt tttagttttg ttagtaaaac cagtgtaacg tccaacacgt ttagcttttg
    83221 gttttacgtt gattgtgtta acattggcaa ctttaacacc ttcgaaagca gcttcaacag
    83281 cttgcttgat caaaagtttg tgtgcacgag tgtcaacttc aaatacatat ttccctgctt
    83341 caagttgagc cattgagctt tcagtgatga caggtttttt gataacatca tacaaattca
    83401 ttatgcaaga acctcctcga ttttagagat agctgcttgt gtgacaagaa gtttgtcgct
    83461 atttgcgatg tcaagaacac ttgcagttgt agcagttgca actttcacgt ttggaaggtt
    83521 acgagctgaa agagctgcga attcatttcc ttcttcaagg ataacaagaa ctttagaatc
    83581 gatgctcaat gctgcaagaa cttttgcaaa ttcagcagtt tttggagctg taaatgaaag
    83641 agcgtctaca gctacgaatt tgttttcagc aactttttca gagtaaactg atttaagagc
    83701 taggcgacga actttttgtg gaagtttgta gccgtatgaa cgtggagttg gtccgaagac
    83761 aacaccacca ccacgccatt gtggtgagcg gatagaacct tgacgagcac gtccagttcc
    83821 tttttgacgc catggtttgc gtccaccacc tgatactgca gagcggtttt taacagcgtg
    83881 tgttccttga cgaaggcttg cgcgttggct gatgattaca tcaaacacaa ctgattcatt
    83941 tggttcgata ccaaatactg catcgttaag aacaacttgg ccagcttctt taccagtttg
    84001 gtcaaataat gttacgtttg ccattgtgac tgatttcccc tttctttatt atttaccagc
    84061 tttaactgct gatttgatag tgataagaga tttcttagca cctggtacgt tacctttgat
    84121 aaggataacg ttcttttctg gaacaacttg tacaacttca aggttttgaa ttgttacgcg
    84181 gtcgccaccc atacgtcctg caaggttttt acctttgaat acgcggttag gtgcaacagg
    84241 ccccatagaa cctggacgac ggtggtaacg agaaccgtga gccattggtc cacgtgattg
    84301 tccgtggcgt ttgataacac cttggaaacc tttaccttta gaagtaccag ttacatcaac
    84361 aacatctcca gctgcgaatg tttcaactgt gatttcagcg ccaacttcca agccttcaac
    84421 gtttttgaat tcacgaatga agcgcttagg agccgtgtta gctttcgcta catgtccttt
    84481 agcaggtttg ttgctcaata cttcgcgttt gtcatcgaaa ccaacttgga tagcgttgta
    84541 tccgtctgtt tcaacagttt taacttgaag aacaacgttt ggagttgctt caataactgt
    84601 tacagggatc aattcgccag cttcagtgaa gatttgagtc attcccactt ttttccctaa
    84661 gattcctttt gtcatgagaa aatagttcct tttctatatt ttttattcaa aaagttttta
    84721 acgagcgttt tttatgctca agtctaagat acaaagggcg tcaaactcaa cgtgaaaata
    84781 ggaaactaac gcagtgtcta acggacaata ggaagtttat ctttttcaca ccgagtttag
    84841 tccgtgttca attagattga aacaccagcc tctgctcttt tatattttag attaaagttt
    84901 gatttctacg tttacaccac ttggaagatc caatttcatc aaggcatcaa ctgttttttg
    84961 agttgggtta acgatatcga tcaaacgttt gtgtgtacgc atttcaaatt gttcgcgaga
    85021 gtctttgtat ttgtgagtcg cacgaatgat tgtgtagagg ctacgttcag ttggaagtgg
    85081 gattggaccc gcaacttgtg cacctgtacg agtagctgat tctacgattt ttgcagccgc
    85141 tgtgtcaagc gtacggtgtt cgtaagcttt caaacggata cggatttttt tgtttgccat
    85201 ctttttctcc ttttcgtcta tctaagataa taggctagct ccacaagaaa accgacacgg
    85261 tgttgcgtgg caatgcaacc gagcgtgtcg caacctcttg tatcaaaact aaggctgtaa
    85321 tttacagcac cataatagaa taacacaaat cccctgcgat tgcaagggat ttgttaggtt
    85381 ttttcgtttt tttgggatga aactgttttc ctactttttc ttcctaaaat tagggatttt
    85441 cttctatatt tcttctatac ataagttaag tcctcttgac atcaaattta tcttctgatt
    85501 gatccactaa gatatccgcc ttagactcag tttctttata gtatcgcaga tactgctccc
    85561 gtctcatctg atggctagcc aatataaagg atgcatcacg atttctcaca gtcgtatctc
    85621 tagcaaggcg tcgctttaat tcggtctcct catccgtgta gaaacagatg gttttttcaa
    85681 agagttcctt gggtagaaag ccaacagaca tcccttcgac aatcaaaatt ggtttgactc
    85741 cagacaagac ctcactagcc ttccaaggtt cttcaattgt caagacatcc atacccgcct
    85801 gcaaggcaag gatatctctc tgcaaactct ccagttcatg cgccactggc agactggctg
    85861 tcaccttttg attcggcgcg tccttgggta ctaccagatg gcgtcctgag gtgatataag
    85921 gatctgtctc tagcaaattt actgtagtag aatctaaagc ttggtacaat tcctgtgcaa
    85981 aggttgattt acctgaagct ccatgaccgt atattcccag tgtcctgact ttccccgtct
    86041 cgatctctga gactagttgg tctactaagt cctttttctt cattctctct tcacctgttc
    86101 atagctttct tttccgtcat tgagcttgtc ccaaatcact acttgcccac ttttgagcga
    86161 tttttgcaca tcgataattc gttggttaga cgaacctcga aactggagca taagatttct
    86221 cttagttcga tcatatcttc catcgacaag aatgtcaatc agtgacaaga gttccagttt
    86281 atctggagtt tccaacatca tttcttccca agtgtagccg gtccaggacc aaatgtcctt
    86341 gtctggcaat tccttccgaa tccgcttaac aagtggcaag agaatcccag tattaagaaa
    86401 aggctcccct cctagtaagg ttaacccctg aacataaggc tgggcaagat ctgccataat
    86461 ctgttcttcc aactcagctg tatagggaat gcctgcattg aaggaccagg tcgctacatt
    86521 ataacacccc tcgcagtgaa acatacagcc tgctacatag agagagttac gcacgccttc
    86581 gccatcaaca aagttaaagg ccttgtagtc aatgatacga ccttgactaa gttcctcgct
    86641 tttccattct tgtggttttg gattattcat tcgctacctc tatccaataa cgctcgactc
    86701 cattgcgagc atcctcaaat attccaccat ttgctagaat gactgctctg ctagcaggat
    86761 tattcacgct acaggtcacc agagctttct tgatgttctt ttccttagca acttgcaagc
    86821 cctgacggag agtctctttt gcataaccct tgcctctttc agatggacgg atggagtagc
    86881 caatgtggcc agcataattc agtaacccct cattcagtct caatcgcaga ttcaaaaatc
    86941 ctagagcaca acctgattca ccaaacaata cgaactgtat cgatggaacg cgattttcag
    87001 gtagccatat tcccatttct ttattacggt taccttctag ccactcctcg taagaaaaat
    87061 cctcaacatc ccaaaatcct ccatcatggg ctgattggct cttttcaaac tctgtcatca
    87121 tatctaaaac agctttctta tccgctaatc ttggtctgcg taattccatc cttacctccc
    87181 actatgagaa aagcgagagc tggctctcac ttttattttt tcttgttctt gtttaaaaat
    87241 tgttctctga agctaagcaa gcgttctttc ttaccagctc cacctttaga gtgtttctcg
    87301 tgataacggg tcacttgtgc gcgcccctta tcgtctagtt gatattttcc catttcattt
    87361 ctttctaatt tgttacttga tgcccagcta ttttaatcgt tgaaccattc atatgtttga
    87421 cacgcgcagc gatttccttg tgacgcccgt tgaccatcgg tcttgcttga ggattaccta
    87481 ggtagccaca agttcgcttc accacatcta ctgttttagg gtcgctattg ccacagtttg
    87541 gacaagcaaa ccctctctca gttggttcaa aatccccttc aaagtcacac ttgtagcaac
    87601 ggtcaatcgg agtattggtg cctagatagc ctacacggtc ataagcataa tcccagacag
    87661 cttccaaggc ctttggattt tgctgaagga ctggatactc acaataatgg atgaaaccac
    87721 ctgacgcacc tgcttctgga tagactttct caaagtccaa tttttcaaac ggtgttggat
    87781 ttttacgaac atcgtagtgg aaagagttgg tgtagtattc cttgtctgtg atatcaggaa
    87841 tagagccaaa cttgtctata tctagtcggc agaaacggtc tgtcagactt tcggatggtg
    87901 ttgagtagat agagaaatgg tagccatatt ggtctgacca ctcttctaca cggcgtttca
    87961 tatcgtgaat gatgtctagc gtgaattcct tagcatctgg attactttcc cagctgttac
    88021 caaagaaaac tgtcgctact tcatacaagc cgatatagcc cagcgaaacg gtagcacgac
    88081 gattcttaaa gagctggtca acactttctt ctttacctag acgatggcca aaagcaccgt
    88141 actgataaag aataggagca tttgctggtg tcgcctcttt agtgcgttcg acacggtaaa
    88201 caagagcatc ttctgcgata ttcattcgct cgttgaagat ttcccagaac ttattcatat
    88261 caccttcaga ctcaagagca atacgaggca gattaaccgt cacaacaccc agattcatgc
    88321 gacctgaatt gacttctaca ccattttcat ccttccatcc ttggaggaaa gaacggcaac
    88381 ccataggcac cttgaaggat cctgtcaagt caacaatctt atcgtaagat aaaacgtctg
    88441 gatacatccg cttggttgca cactctagag ccaactgctt gatgtcatag ttgggagttc
    88501 cttcctctaa gttgaggcct cttttaagcg taaagataag tttaggaaag atagccgtac
    88561 ggtgttctga accaagaccc ttgatgcgaa tgtttaaaat agctttttga atttctcgtt
    88621 caaaacgact ggttcccaga ccaaaaccta acgaagtaaa aggtgtttgt ccatttgaag
    88681 tgaagagagt attgatttca tactcaagag attgcatggc atcgtagatg tccttttgcg
    88741 ctttcttcca agcgtaatct tcctgttttt caggcaatac ccactcttct gcatctttga
    88801 gatgtttttg ataattcttc tctgcataag gcgccaaaat ttcatcgata cggtcagctg
    88861 aacagccacc gtactggcta gaagcaacgt tggcaatgat ttgagaaatc tgtgctgtcg
    88921 cagtctggat agacttggga ctctctacct ctgcatttcc aatcttaaaa ccattttcca
    88981 acataccctt aaaatcaatc aaacagcagt tggtcatagg ggtataggga ctgtagtcca
    89041 aatcgtgata gtggatatcc cccttttggt gggcattggc tacgtgctta ggaagcattt
    89101 gcagtccgat tgatttccca acaatccctg ctgtcaaatc acgctgagtg ttaaagacat
    89161 cactgtcttt attagcgttt tcattgacaa ctgtctggtc tttgttgaga agtttatgaa
    89221 tactaaagtt gatatccgtc gcttttgagc gctcaaaatc cctctgtgtc cgataagtaa
    89281 tatactcctc agccagcgca tattctttgg cttcaaggag ttcatgttct acgatatttt
    89341 gaatttcgta aatcttaatt ccctgtggaa agcgactatg aatttctgta ataattcgct
    89401 cagtcagatc attgaggcat ttttcaacca ggggtgtcac atccataacc ttgtcagccg
    89461 ccttgtggag agccttgtca atcttgtcca catcaaatac aacacgtctc ccatctcgtt
    89521 tctcgacgaa gagagttggc aaaattgtaa ttttttcttc tagtgcaatc atatgcatgc
    89581 tcttttctaa aatgttcttt ctaaaaagta ttataccact ctaaaaagaa aaatcaatat
    89641 cttgtgttaa aaatcctaaa atttttaaaa atacacaaga tattgatttg gttatttaat
    89701 tttatagact ttaaactctg agtaatcagt ctttacttgt tggtaatttt cttttaagag
    89761 tgtttccact tcagaccaga ctaccacctt atcatttacc acaatcacct taggttgttt
    89821 ttctttcaag tcattaagta acttattacg attttcctca gttgctgtat agtgcaacgg
    89881 ggacaaaatc gccgatggcg acaagcgctc actcttacga taaagagtcg cagtatcatc
    89941 ccatgcatag atagcatctt ccgtatttgt ctcctctttt accaaatcag caagacgatt
    90001 acgttcttga taaggtactg gataaaggac aaacttcatc aaaaaaggaa cagacaaaag
    90061 atagacaaac ccaaaaacta gcagatatag atttcctttg aagaaacgac tccataggct
    90121 aactggcgtt tctcttcggc ttcttctagc actacgcccc ctctgttgac tcttaatatt
    90181 ggttaccaat aaaagtagga aaacagggaa gacgaccatc aaataagaag cgtgcagagg
    90241 ctcttgtgaa aagaaaagta aaatcaaacc taaaattacc acaagacttg caggaaccga
    90301 aatgacgtat agtttaaagg gtttggattg aaagagacct aaaaagatac aaaccacaaa
    90361 tcccaaacca agggacaaca agccataaaa aaacatattc tctaaaattt tagaagtaaa
    90421 atcaaagcga atactgtcaa taggataacg aataccacta atcgcatccc caaaacttcc
    90481 tgttgcagca ctatagtagg cagttggata aaagacaagt gaaaaaccta aagccactgc
    90541 aagaaactga taaaacccat gcgcaaagcg tctatgccca aggttaaaga ccaacaagcc
    90601 taaactcact acagcaataa acaggagcga tgataaggga gcaaagaaaa atccgcctgc
    90661 caaagctagc ccaatccgta caaatccctt atcatggctt ggattgctta ggtaagccgc
    90721 aactaaacta aaggctgcga ataagaaagg aagcgctaaa agagtcgcat agcctccacc
    90781 aaaagcaaga cctgtaacta gcatgtaaaa aatagtcacc agatgtccag cttggtctcc
    90841 ttgctctgtc aaggtgtccg ctgatctaaa aaggaaaaat ccgcctgcta ccaaggctaa
    90901 ccactcaaag atggcaaaga aaaatccgcc ctgactcacg taagtcagca aataataaag
    90961 caaaccttga cttccataat agtcgctgta aatcttccct gtctgatgaa gcgcccaacc
    91021 tgcataaaaa tcctgcactt cttgtgcact cattaagtcg agtaatagcg gtactcctag
    91081 agttatcccc gttacaagcg tactccatag taaaattttc actaaaggaa gacgacttga
    91141 ttcacgatga tgcgattctt gttcgatttg gtattctaga ggttcacgat tctccttatg
    91201 aacttcttct actctaccat acacactcat atcgtttctc ctgttcaatt tatctgtctt
    91261 agtatatcaa aaagtcctag gattgtcagc ttgcgatggc tgtttgagtg attttttgca
    91321 tagtttcaca aaggtttcaa tttcccgaaa gcggtgtaaa tgtgtctgtt tgaactcaat
    91381 catatcattc acttcttcct tagttagcat gaattcccct cctctttctt tctattcgta
    91441 aaagacaaga aaaataggtc tggtttgtat cctaagttct agatttctta taagataggg
    91501 gcgaatagct gggcgatttc ttttacaagc ttttgatacc agctcgtttt gatagaatga
    91561 ggatagactt cctgagaatc tgcaaatata tttcgaaaat ctcgggcgat ttcccttata
    91621 gaaggagttt tatagagtaa gactgcattt tcataatggt gtaccaagct ccggtagtcg
    91681 agattgattg tccccaccac cgcaaaatct tcgtctacca acatctgctt actatgaata
    91741 aaacctggac tatactcata aatccgaaca ccagcagaaa gaaggtcggg ataagctcct
    91801 ctcgtgacta actgaatgaa cttcttatct ggtatgtaag gggtgataat tcgaacatcg
    91861 acccctctca tagctgcatt tttgattgtc tctgttaaat cataatctat aatcaaataa
    91921 ggtgtcgtaa tatagaccga ttccgttgct tgattgatta aactctgata aacttttttc
    91981 cctacctgcg ctcgaaaaat tggcttgggt ccacttccgt atggaatggt taaaccgtca
    92041 ctcgggatag aatgattttc taaatgatat tgatcaaaat cactaatttc tcctcgatta
    92101 atgtaccaag tggtcaaaaa taagcgtgtc agggctttta ctgctagtcc gtctaagcga
    92161 attccactat ccttccaata accaaatctc tcgacgtggt taatgtactc atctgccaga
    92221 ttgaccccac cagtataggc tatctgacca tcaacaatca atatttttct atgatctctg
    92281 ttattataag ccactgtcaa acgaggaata actttattga atttatgggc ctcgatgccc
    92341 agctgacgaa gtcgatgtgc ataatctcct gttaaagtag ccatacagcc gatatcatca
    92401 tagagcatct taacctctac accctgagct accttttgct ctagtatatc tagtatgcga
    92461 ttccacatca aaccttcttc tataatgtaa tattccaaga aaataaattt ctcagccttt
    92521 ttaagatctt ctaccatctt tttccacata gcttctccgt taggaaaaaa tgtagaggca
    92581 gtttgatcat agatgtcagc attggtatcc atactcaata aggacttgat gactccataa
    92641 gctgccttgt cactttcttt taatttctct tttagtagct ggctatttgc ttcttggaaa
    92701 tgcatagagc ctagcttctt cagttgtttg atttcttttt tggacaatcg cctttcacca
    92761 aacatcagat agagcaaggg accaaatact ggcacaaagg ctactaacaa ccaggttacc
    92821 ttattctcag gagtcgtatt acggttgact atcgaaatga ttgtgatgat actcagtaga
    92881 atgaggacag taatccataa aatgggagcc atgcgtccta aataaagaaa gagaccaaaa
    92941 acaagacaaa gttcaagtaa cataatcgaa agactaaagc catacttgga catcaataat
    93001 tgaaatttcc tatatttcat atcccctcct tgatagtttg aatgctaaaa acaagtaatt
    93061 gatactagta taacgcaggt attcggtaga aggcaagtat ttatgattat tttctaggta
    93121 aaagtaaaaa ggctgaaaaa tccagccctt tctacttgca tagtcttatt tagttaaaac
    93181 gatttggtcc gatgggtctc tatccatatc atctacgacg atttgattac cgtttacagt
    93241 gtaaattttg acatcatcgc caataatcat gcgttgattt gctgaatcaa atgtaacctg
    93301 tttgactttc tgatccccgt cagattcgag ctcagtccat gtaccagtcg ttccagttac
    93361 cactaaagtg atacggtctc cgtcatcctg accagtataa gtcccatcaa tatcggtcgg
    93421 ttgagcaaca ggttggtttt gtactggagc cgcttgattt tggttacctc ctgcatttgc
    93481 agtattggta ttctgttgag caggctgttg gacctgctga gcaacaggct gttgaacctg
    93541 ttgagctctt tgtgaacaag ctactaagag actaaaactt gctagagaag caagagaaag
    93601 tgtgaatctt tttaatttca tgatgaattt cctttctgct accaatttag agaaattttc
    93661 tctaaccagc aattccccta gtataacaag ttcaaaaaag ggggtcaatt tatctgctca
    93721 cggtccagca ggtagccccg tacttctgag ataaaataga gagaccctgt aacgaacagc
    93781 aagtcttgag cgtctgccct ttcttcgaaa ctgctgataa attctcggta agagggaatt
    93841 acatggtaac ctgttacatc tgtctcgtcc aaagaccctt gatagtcaaa gccggtcatt
    93901 ttgagttcca cttgaggtaa attttcagtc agataaccca acatcccttg ataatcctta
    93961 cgtttcaagg atccaaagag gatttgaggt cgatagcctt cctgctcttt ttctttgata
    94021 aactcaacca agcgagtcaa ggcagggagg ttatgagcac catccaagta aatctgtggg
    94081 cgaatacgct ccaagcgacc agcccaatgg gtttgttcca aggtctttct tacagcctgt
    94141 tcatcaatag cttcctttct ttctcccata aaaagaagaa aagtttgcaa cgccaaggcc
    94201 gcattctcct gctgataggc tccttctaag cctatgttca gctgtgaaag atttagtaaa
    94261 gagcttgaaa aatcaccatt cagcactgaa aaatcttgac ctgcctgata aaggtcaaca
    94321 gctaaagatt cggctttttt ctgacagata agcctagctt ctggaggcaa tttcgcaatc
    94381 actgccttct taccagcctt gaaaatacca gctttctgct ctgcaattgc ttctagacta
    94441 tcacccaagg tttcttgatg gtcaagccca atggaggtga tgacagcaag ctctccagtt
    94501 accacattgg tcgtgtcaag taagccacca attcccactt ctaataaaac caaatccacc
    94561 tcttgctccc taaaataaag aaaagcaacc aaggtcagca attcaaaaaa ggacaactgg
    94621 tcaggagttt gcagaagcgt tttctccatc tccttgacct gatcagccaa acggataaag
    94681 tctgcgtctg ctataggttg cccattaatg caaattcggt cattgatgga tacgatatga
    94741 ggggaggtaa aggtcgcaac ttttttgcca tgccccataa ataattccct cataaaagca
    94801 atggtagatc ctttcccatt agtccctgtt acgtggataa tagggtaaga ctgctcagga
    94861 tttcctaaca aatccaccgc ttgctgcatt cggcccaaac ctgatcgaaa atttaaacca
    94921 atccgactat ggagccattc ttctacttca aacatacaca tctccttgac aaaagtccaa
    94981 tcaattatcg cattaaagta tggttactaa taaaaacaag gccaggattt tcgtcccgac
    95041 ctcttacctg gttagctaat aactagccac tatgaatgtg aatatgggct aaaaacatcc
    95101 actagatgtt ccaactcttc tcaatttcta agagttgggg taaaaatgtt cactggacgt
    95161 tccaactctt ccccatttct gggagttggg ctgatacagt ctcccagact taccagctct
    95221 atcttattta aaggagctgg gctaaaaacg tcccccggac gtttttactc ctccataaag
    95281 ctgttgaaga cttcttcaat catgttccat tcgtcttctg agtcttctgg gattggttgc
    95341 aattcgcctt ctgttccatc ttcgttttcg atgaatgagt aagcttggat ttcaacttgt
    95401 ccgtcttcgt cttcttctgc gttaactggt actagaagaa catagttttt accaaattct
    95461 tcttttccat caattgtcaa aaggatttca aacaaggttt catttccttg ctcatctact
    95521 agtgtgatta gttcacgttc ttcgtggtcg tggttatgat cgtgtgacat agcctctcct
    95581 ttatattaaa attttctatc taaataattt tgtaaaatca gctgagctgc taacttatca
    95641 atgactttct tgcgcttatt gcgactgata tctgcttgtt caatcaacat gcgctcagca
    95701 gccactgttg tcaagcgttc atcctgatag tctactggta aaccaaaaaa ctcttctagc
    95761 tttgctccgt aggcttgact agcttctacg cgcggtccac ttgtattgtt catgttttta
    95821 ggcaagccca ctacaaatcg ttccaccttg taagtatcaa ccaattcctt aacgcggtca
    95881 aaaccaaatt ggccttgttc ttcatttatc tggatgattt caagcccttg agctgtaaaa
    95941 ccaagcggat cgctaatcgc cacccctacc gtttttgaac cgacgtccaa tcccataatt
    96001 ctcataggtt atagatcgac tccttgtcct ttgaggtagt agcgaaccaa ttcctcaacg
    96061 atttcatcac gctcatactt acggatttga tttcgtgcat tattataacg aggaacgtag
    96121 gcagggtctc cactcaatac gtaacctacg atttggttaa ttgggttgta acccttatcg
    96181 ttcaacgaag cataaacatc tgtcaaagtt tcgctaattt cttttttatt ggaatcgtcc
    96241 aatttaaaac gtactgtttc ttcagtaaat cccattctaa caccctcttt ccttagaata
    96301 gtaccattat agcataattc cttaccttct acaattcagg cagtctattt atttggattt
    96361 tctattgttc tgtcgcgcca tttgccaatc tatctgaaat atatttgctt ggttcatttt
    96421 tcaaaagatt ttccaaacca atattcttca gatgttccaa ctgggaagcc ttcttgacat
    96481 ccagaacttg aaaatcaaaa ctagtcgttg tttgaagttc cgttgcgctc aatagttttg
    96541 tttcaagttt gaaacctgcc aatttacgag cttcaatgat agacttatcc ttctcctccg
    96601 cttcaagaag agctttttga gtttcctcca ctccatgttg gtcaatataa gtcttcaact
    96661 catcagagac tggacgtttt tgttggatag ttagactcaa aaaagtcttg tctttataag
    96721 taattgtttg tgtctgctgg ctaccatcat ctgacttggg caagaccaaa gtcttagtta
    96781 caactgtatt cttctcagca ttttcaataa ctggcaatgc cgactgaagc gtatcttttt
    96841 ctgtttttgt agctggtcca gtttcttttt tctgtccgca accaaccagg acaaaaagga
    96901 aagctagact aacaagaact atttttttca tttctttctt ctttcttttt gaaattaaaa
    96961 tagaataaga ctgggaagtg ctcccagcct tgatgtttat agagctgcac gcaaacgtgc
    97021 ttctgcattt tctacattac ggacagagcg tggtaggaag gcacgaatat cgtcttcctt
    97081 gtagccaact tgcaggcgtt tttcatctac aaggattggg ctctttaaaa ttctcggtgt
    97141 ttccataatc agattgagaa cttcattgac actcaaatct tcaatatcca ctccaagggc
    97201 tttggcatag cgatttttag atgaaacgat gctggctatt ccgttatctg ttttggttag
    97261 aatatccagt aattcttctc tcgtaattcc ttctttacca aggttttgtt ctttataact
    97321 taactggtgg gcattgagcc aggtttttgc ttttttacag ctagtacaac ttgagactgt
    97381 ataaatttta atcatgtacc tacccctttc gctacatgtt actatcagtt tagtctatta
    97441 taccataaaa aacatccgac ttgcgaccta tttttaattt tttttgactt ttttcgtcat
    97501 tttcgtactt ttttcttgac aaacaactaa atgactatca actcttttgg agctagggtc
    97561 aataattcac aacctgtctc tgtaatcagg atatcatcct cgatacgaac gccatatttg
    97621 ccttcgatat agatacctgg ttcatcggtc aaggccatac ctgtcttaat agtttctgta
    97681 gaagtctggc taaagtaggg ttcctcatgg atatccagac caataccgtg gccaatgccg
    97741 tgagtaaagt agtcgccata acctgcctca atgataatat cacgagggat tttgtcaaag
    97801 tcacggaaac ctaagcctgc cttagcttgg tcaatcaagg cttggttagc ttttagaacc
    97861 gtattgtaaa tctctgcctg ctcatcgcta acatgcccta gatagatagt ccgggtcata
    97921 tcactgacat agtggtcata gagacagccg aagtccatgg taatggcttc tcccaactcc
    97981 actggtttgt gcattggatg ggcatggggt ttagaagaat tgataccgct agctaggatc
    98041 gtatcaaaag ataagccaga tgctcccaac tcacgcatgc ggaagtcaag gaagttggca
    98101 atctcaattt cagtttttcc tggtttgata aagtcaagcg catcgcggaa agcttggtct
    98161 gagatagaac aagccttgcg aatcgctgca atctctgcct catccttaat catacgaaga
    98221 ccttccacaa actgagtttg tggaagcaag ttcaaacctg caaaagctgc ctgcatacgg
    98281 tggtaataag acactgaaat ctcatcttca aaaccgatac gagtcaagcc catgtcctta
    98341 acaattcctg caatgacagc caattcatca cgatcagcca caatctcaaa accactggtt
    98401 tcttgcttag ctgcgatgat atagcgagag tctgtcacta agacctgacg gtcacggctg
    98461 ataaagactg ttccgtttga gccccaaaaa ccagtcaaat aatagacgtt tttaagattg
    98521 ttgatgatga taccatctag ttctttttct tgcattttag ctagaaatgc ttgtacgcgt
    98581 ttattcatga tgtaactttc ctttcaaata gtgtcctgta tagctggctt cgttggcagc
    98641 tacttcttct ggagttcctg ttacgatgat ggttccacca ccgacaccgc cctcaggtcc
    98701 caagtcaatg atatggtctg ccgtcttgat aacatccaga ttgtgctcga tgacgaggac
    98761 tgtattgccg tcgtctacaa agcgagctaa aaccttgagc aggcgagcaa tgtcctctgt
    98821 atgaagccct gtcgtcggct catccagaat gtagaaagat tttcctgtcg agcgtttgtg
    98881 gagttcgcta gctaacttca tacgttgggc ttctccccca gaaagggtgg tagctggctg
    98941 tcccaaggtc acatagccta gacctacatc cttgatggtc tggagtttgc gttgaatttt
    99001 cggaatgtgt tggaaaaatt ctaccgcatc gttgaccgtc atatccaaga cctgcgaaat
    99061 attcttttcc ttgtagtgaa cttctagggt ttcactgtta tagcgggttc cgtggcaaac
    99121 ttcacaagcc acataaacat ctggcaagaa gtgcatctca atcttgataa tcccgtcacc
    99181 tgagcaagct tcacagcgac ctcccttgac gttgaaactg aagcgcccct tcttgtagcc
    99241 tcgaatcttg gcttcatttg tctgagcaaa aaggtcacgt atatcgtcaa aaactcctgt
    99301 ataggtagct gggttagacc tcggcgtccg tccgataggg ctctggtcaa tatcaatcaa
    99361 acggtcgaca tgctcaatcc ctgtaatagt cttaaactta ccaggtttgt ctgaattacg
    99421 gttgagcttc tgggcaatgg cttttttgag aatgctgttg attagagtcg atttccctga
    99481 acccgacaca cctgtcactg cgataaattt tcctagtgga aagcgagccg tgacattttg
    99541 caagttgttc tcacgcgctc ctatcacttc aataaaacga ccatttccga cacggcgctc
    99601 ttctggtact gggatgacac gtttgcctga caagtactga cctgtgatag acttgctgtt
    99661 gcgagccact tgcttaggtg tacctgctgc aacaatctca ccaccaaaaa caccggcacc
    99721 aggaccaacg tcaatcagat aatcagcttc acgcatggta tcttcgtcgt gttccaccac
    99781 gataagagta ttgcccaagt cacgcatctt tttcagactg gcaatcaggc ggtcattgtc
    99841 cctctggtga agaccgattg acggctcgtc taggatatag aggacgcctg ataggttgga
    99901 accaatctgg gttgccaaac gaatgcgctg actttcccca cctgaaaggg ttcctgctga
    99961 acgtgacagg gttagatagt taagacccac attattaagg aaggtcaaac gatccttgat
   100021 ttccttgaga atgggacgag caatgatggc ttcattttca gacaaagtta actggctcac
   100081 caagtccaag tggtcagcga tagacaggtc tgagatttct ccaatatgtg gcccttgctg
   100141 gccgcccaca cggacagaca aggcctggtc attgagacga tagccttgac aggttccgca
   100201 ggtcagctca ttcatgtaga gacgcatctg agtgcgagtg taatcgctat tggtttcatg
   100261 gtaacgacgt ttgatattat tgataactcc ctcaaacgga atgtcgatat cgcgcacgcc
   100321 accaaattca ttctcatagt ggaaatggaa ttccttacca tctgacccat agagaatcaa
   100381 gttcttatct tcttctgaca ggtcctcaaa aggcttatcc atagccactc caaagacttt
   100441 catggcctgc tctaacatgt ttggatagta gttggatgag ataggattcc aaggtgccag
   100501 cgctccctca tgtaaggttt tgctggcatc tggcactacc aaatcagtat ccacctccag
   100561 cttaatcccc aagccgtcac actcactaca agagccaaag ggagcattga aagagaagag
   100621 acgaggttct aactctggga cagtaaatcc acaaactgga caggcataat gctcagagaa
   100681 caacaactca gagtcgtcca tggtgtcgat aatcacataa ccttctgcga tacgaagggc
   100741 agcttcaatg gaatcaaaga gacggctacg aatgccctcc ttgataacaa tacggtcaac
   100801 cacgacatcg atattgtgtt gcttgctctt agacaactct ggcacttcgg tcacatcata
   100861 gacttcccca tccacacgaa cacgaacata cccgtctttc tgaaccttct cgataacact
   100921 cttatgttgg ccttttttct tgcggatgac aggagccaag atctgcaagc gctggcgttc
   100981 aggtaactcc aaaaccttat caacgatttg ctccacagaa gaagcattga tagctccatg
   101041 tccgttgata cagtaaggcg tccccacacg tgcgtagagg agacgcagat agtcattgat
   101101 ttcagtcgtc gttcccaccg tcgagcgagg atttttacta gtcgttttct ggtcgatgga
   101161 aatagctggg ctgagaccat caatggcatc tacatctggt ttttccatat ttcccaagaa
   101221 ctgacgagcg taggcagaca aactctctac atagcgacgt tgtccctccg catagagagt
   101281 atcaaaagcc agactggact tccctgaacc tgacaagcca gtcacgacaa ccaacttgtc
   101341 tcgcggaatc tccacatcaa tattttttaa attatgggca cgcgccccat gaatgacaat
   101401 tttatcttgc atctttgttc tttctagtcc attattgctt accattatac caaaaaaagt
   101461 gagattctat tacccaaaag gccgattttg tagtataatc aacaatcgct tattttatgt
   101521 ttccttaggg cttcctaacc cttatatcac gcgcttttta ataaaaatta ctaacattac
   101581 tttttactac ttgctccccc aaagtacgca aaaaggggag caaaaaagcc ccacaaaagg
   101641 gctaagattt gacgagttca gcaggcaaga aactagcacg gtcaaacgtg cttttttatt
   101701 gctggttgct gatagatata ttataccatg aagcgcgtgg tttataagat tatgacctca
   101761 caaaagcccc cagattcgtt tctgagggtt tgtagtttat ccatggtgtt ttagttgtcc
   101821 agtacgaaac aaagcgaaat acgggcgaat atgtggctta ggactccccc atactctcct
   101881 aattccgtgg taaggttaaa tcaatccccg tttacaatac ctgttaagtg ttctatagct
   101941 ttttgcctta taatgtatac tgtagtattt gatctatcta tttcttcagc cacctccgaa
   102001 actacaagat cattcaagta aaaaagtctt agaacagaac gctcaagcgg attggccagt
   102061 ttatcgatta gctcagatat tttcattctc tcttcagtaa gtcgctcaat tctctgtaaa
   102121 gtgtcctctt ttagcttcag aacacttata agattgttct ctgtcttatt ctctctactt
   102181 gtctgcaccc tgctatggct tagtgttggt tttttgataa tgccaccttc cagggtttcc
   102241 aattccaaat ataagccttt gatctccttg tttatccact taacgccctc tagtttttct
   102301 tttacttgct ctggtgtcat gcctcggcct cctttgtgat ataatagttt tatggaataa
   102361 ttcataaagg agtcagccct gtgctggctt tttttcattt tctctagctt cgctctaggt
   102421 tcaagtccat tctccatacc atttgataag caattaaggg atgtttttat ctctcttatt
   102481 tccttgtcat tctgcaagca attaaggcaa gttatttctt tgcttatctg cttatcattt
   102541 tgtaagcaac aaatccaaaa taacagactt ttaaactgct cttatctcct tatcatttgg
   102601 taggaaaata aggggagtta ttttagttct tatttccctg tcattttgta aggagaaaat
   102661 tcaaattaag gaagctaata agtctcctta tctccttaca gtttttcagg gagcaaaatc
   102721 aaaataagcg atgttatttc ctgtcttatt tccttcccgt ttgacaagga gaaaaacgaa
   102781 aataaggggc ttttaaattc gtcttaactc cctatcgttt tgtaagcagt taagaaggct
   102841 tattgtcgtc cttatctgct tgtcattctg caaggagtag atccgaaata agagggctaa
   102901 aaacttctct tatctgcttg tcgtttctca gggggttaag gagggttttt attgctctta
   102961 tctacttgat aaatgatagg ggggatatag ccactttctc ggcgttcgct cggagttcaa
   103021 cacacataac cctgccattt gtcaggcata tttactgcca ctacctaagc aaaatctcac
   103081 cttttctaac cctcggtaaa cctctctacc tttgtaaaac cttagtattt ttaagtatgt
   103141 aaccttgtac taaccttgta ctttttatat atgctacctt accaaaacct taccattgga
   103201 aaacttcgat accttaccgt aaccttaccg ttctatggtt ctaaaaaagt agctatacct
   103261 tgtggtaacc ttggggttct atcactagaa aaaagccctg taccttgcta aaaccttgct
   103321 attttgaagt atgtgacctt agcctaatct tagccttttt taaatattca acctcaccct
   103381 tacctcaccc ttttttggaa cgcttactgc accctttttt tggaacgcta tacttaatta
   103441 aatccttgat atatctagct tttttaacat tcaaaccgtc taatatgtag tatttgtttg
   103501 ttttgtaaat tgcacactac tacaaattac cttagagaac tcaaaccatt cagccaaaag
   103561 ctatcccctt ttctggtgta gttaataaac ttttgataat gcttgtaata tcgtttctgt
   103621 ttcatgtatt ttggtctttc aggaaaacta tcaaacatat atccgccacg tctaggactc
   103681 caccctggtt ctacctttct agcttctttt agtgcaagct cccagtagta ttggcaatcc
   103741 gttttactgc ggttcagggt gtgcttgtgg atatctagac aagtaccgca actaaaatac
   103801 aaataccgtt tataaagcaa cctgcaccgt ctaccacaat cagggcaaag aaaaaaatat
   103861 cgattacctc ccttagttcc tgctattctg tctaattcaa atgactctcc accaaaatca
   103921 atcattaaac tatccaaatc aatctctaaa cgttgaccat ccaactcggc tataccctta
   103981 gatattcctc tcagcttcat tggtttagtg attgcttcta ttgctaactg cttcattatt
   104041 tccccctata tggaaaaacc caaaactatt gacttgatag caaaaagggg attgctcccc
   104101 tgtattctac ttcaaatgct ctgtataacc agcaaggcct ttatattcgc cctctacgtc
   104161 caacttttgg agtaggctaa tactttcatc gcccagcatt tccaacgtag caaaagcagt
   104221 catagagtcc atagggatag gcttatcaga aagcaggcgg tcagcatagt ctaatagttc
   104281 cagctcgtag tctgtgacct tattcagtaa actctcaaag tcctctgact ctttgagttg
   104341 gagcacgcgc tcccgtttgt aacgttcttc aaatgcttca gcctctcctg gttgtttgtg
   104401 gtagtcttta aaactgtcac aaatacgctt aaaggtcttg tttagcttgt gatcttccac
   104461 atactcagct actagcgtgc ctttatcctt gtaggtcaat gagattacag gctggcaata
   104521 tgttccagtc atatatccca gtaacgcgtg acctgctacc agagctgtat ctaggtcttt
   104581 aaattcgtaa gtgaaagtaa atgttttggc tttagatgaa aatgttttta atgtcatgtt
   104641 gtttttcctc tttctgtttt taagggtgtc actagtagtt acaccattgc aagggggtcg
   104701 gtactatcta ccccattttg ttatctgtat aataccaata cgatagccac cgaattaaag
   104761 gattcactag atggtgtacc agaaaattta acgtccagca cttcaacagt tgccatgaag
   104821 tcatcgatct ctttctcaaa gtcttctttt tcccatcgtc tagtatattc aaatagttta
   104881 actttcatgt tgttgtcatt tctttgtttt aaggtaaatt atgtaatatt tttcgttttc
   104941 tgtgaccttc tgtgaccttt tgtgacaaag aacgtcacac gttcaaaccc ttgaggctct
   105001 aggtgtttca ccacccctgt gaccctgtga cgttcttttg ttttatcgtt cctatatata
   105061 aatactgtat ttttctctat atataagagt tggaaagaat gtcacaacgt cacacctatt
   105121 cccctaaagt tagatatatc aaggcttcaa ggggtgtgac cttctttttt gagaacgtca
   105181 cacaacgtca cacttttttc aagaaaatca gtattatcaa gggtttaagc aaaaaaagaa
   105241 cgtcacactt attcttgttt agtgatagag tgttgaggtg tccgcatttt tatcttgtca
   105301 acgtcccatg cctctagttt ttcaaaatct tctggagaaa ctcttttctt tcttagagaa
   105361 taccgattag gtgtcaactg ttgtaagtgc ttgatagttt ctttaccagc cccgtaaaca
   105421 ttgggcttgg gtattcccat atcttcggca tagtgcttta gtgatcttgt aacgataaaa
   105481 acaggtacta cgtccagctc atgccaacct ttttccatgt attcatgctt aacccatgaa
   105541 agtaagtagt cattatcttc ctggtattct tctaggagtc ctttaactgc tttaggttcg
   105601 ataaagtgag taaatggctc ttgattgata gctttgtaga gggcatattc taggacttcc
   105661 ttgtttgcta aaaactcatt ttttatccaa ggtttttcct tctccccgtt aaagtcagca
   105721 ttaaaaggga caatcataat tctacgatac cagccttttg tcttgttgcc accattgggg
   105781 atataattcc ctgaaaagat attgaataac ttgaaagtag cttcaaaggc tgggcgtcct
   105841 tttggattga ctagaacagt gtcgccacta gtgatactca ttaaatcaga cggatttttt
   105901 aagtattcgt taggtgcttc atccccaata ttacaaacct tacctaccaa ggtctccaag
   105961 ttatgctttt cagcaaactg tgcaggcttt aaggctgata tattgctttc ccctatcagg
   106021 ttgataagga agcgctgaaa tgtcccttta ccattgttac cgtccccgta gaagatagca
   106081 aacttatttc gagtatggtt agggttaata gcttcaagga taatctgcca aaacagtgtt
   106141 accagttcac tatcattaca agcgattgag ttcaaccaat catcaaaagt ttttccctct
   106201 ctatctgttg ggactcgttt aggcgcgtgg taggccgtgc ttatcttact tgtaattaca
   106261 tacttaggac taaaggggag tagttcctta gtttctaagt tgataatgcc gttctgtacg
   106321 ggaatgaggt tagcactttc taaaggtttt cgtatctttg ccaatgttct aaccattaac
   106381 ttaatctgtg gccactctct gggtttaatt ctaacgtcaa aggtcttaca caaaagattg
   106441 aatagatcat tactagcggt atagataccc tcgtctaaat catagatata gagtaggcta
   106501 taatcaggta tattgctctt gctgataaaa gtaaatgtga caatctcgct cagtatttta
   106561 gctactgtga aggtttgggg catggcaacc ttttcggtaa cgtcccctgt gttctcattt
   106621 accttagttt cagtatgttc tgcccgccat tcttctccag ctttaaagat acgattttca
   106681 agctccttca tcgttctagg agggtgttct tgctccatta cctccaagat ttcacttttt
   106741 aggtttgcta attcttctag ttctatggtt ctaacctctc tttctatatt cagcccgtgc
   106801 tatactgcta aaagtgcggt ctagctcctc aatcggcaat ggttcaactg tcacgctatt
   106861 ggctatcttt gtaagttcat aggctgtctc taggtcacaa tcaacccact tattaaagag
   106921 taagcctaca aatcgtgtca gtgctacgtt gcgccctccc tcgtctccaa atccgttgaa
   106981 aagcgtgtca atgatcctca tggtcataga tttctgcccg cttggccttg gagtgtatgg
   107041 aaggcttgcc gcattctgtt tgactggttc agccgttgtc tgtggtactg gataatcaag
   107101 tccatgctct acaatctttt gataacttgc tgggtcgcct gttgtgactg gtagcccttg
   107161 gagttgtgac catgttaaac tggccatatc aaaggggagt ccaatcttgt cagcaatctc
   107221 tttcactacc tgcttatagg tcgcctcatt catcacgttg tcaggcttca ctacaaggcg
   107281 aaaacggggc ttttctaagc tatgtttgat agtcgggtat aagatgtaag agtagccaaa
   107341 taaagcgcta gaaatggctt ttataaagcc ctcagacgtc ccctgtatat cgtcataatc
   107401 aaggaaaatc aaatcccgat agattagact ggagttgttt cgcttgtaac tgccatgctt
   107461 ttctggcgtc actttgccac ttatacagta aggcgcttga gttcgcttgt attcctcaat
   107521 atctgcccct tcaggaacta ctaagggctt gaatcgttca atatactgga aaggctcaat
   107581 tttatcaaat ggatagacaa gattactctg aaagccttta gcctcataaa ttgtcatact
   107641 atcgcccctt tttgcgtttt ttcttcagct ttttaagcct ttgctgttcc tttagctggt
   107701 ctagggttgg cctgcgctct ttgtaaaatt taatattgtg ataatgccct ttattatctg
   107761 ccggatgaat actatacctt gccattttcc acccccaaaa acttccagat gtcagatatt
   107821 ttataataga ttttcctagt atcttctagc ggtggctgat accgtcttag ccctgctttt
   107881 tcccactttt ggagtgtcat gtattttata tctaactcgt ccatgacttc ctgggctgat
   107941 attaaacctg tcagtcgtgg cttgactgta tcacgcgctt ccaggtatct ttctactacc
   108001 tccagaatgc catgcgctag gtcttgctca ctttctcggc ttaggctaaa catatccgcc
   108061 cacctccttc aaggtttctt tgtaactctc taaatcagca ttcaaaagga cagttaggcg
   108121 tttctgttct tcctgtactt ggttatagaa tgcctttgct ccgtccagta gctcctcttt
   108181 gttagctggg ataaaatatc ctctaaatgt cccatggcga accccaacaa taggaacact
   108241 atgacgcgtg attagacggc tgataatatc ttgtacggtt ctttccgcca gcttagttat
   108301 aaggctgatt tctgcccctg ttatggagtt ctcagcccct accttgatta gtcttaatac
   108361 tcgtttgtca ttctctgata gactcattca gttcctccgt aaactcttac ccctgcaagc
   108421 tggatataac gcccataatc agggcttaaa tcctcgctag gtgtttctat cctctgttgg
   108481 ttttctcgct caaattgggc gctttttttg cggtctcggt ggtttaggta aagcagtaag
   108541 ccaatcaata ccaccataaa gattaccgat tgtgtattgg tcaaatctaa ctcattcatg
   108601 ttatgccctc gcttgataat tcttgataaa ttccacttgt ttttcatgtt tcatcttcag
   108661 gtattcgtct acctcctcag tgcttacttt tcgatctaca aaatcagcaa taaactggaa
   108721 gaggttgggg cgtttttcct taatttcagc cattacttca tcaaactctg cttgtgtcat
   108781 gttgtctagg tttagtgtca ttgcattgcc tcctcaaact tctctataag acaactttta
   108841 tttactctct gagttccatt tttagagtta aaaagaatat cttttaaggt tatagtagcc
   108901 tctaaatact ccttttcagc atgttctata tacgcctgtt gctctgcttc gttgtcaaaa
   108961 aagtgcatag cttggcgttt aaagaatgct tgtcgcatag cgtccatttc aaaaatacca
   109021 gcgtggaaaa acattcccgt agtgctttta gaaactgcct cgattttatg gctgtcattc
   109081 aattcaggaa gttcaatcca aagtaaacgg tgtaaatttt ctttgatgaa ttttgtctga
   109141 tttgccaata atgaaagtct actaagccca tttttttcgc caatttctcg catttctgcg
   109201 ctaattctgt ctatatgtct agttaaattc tcgtatgttg tttctgtcat gttttttacc
   109261 tttgtttcta tgttgtgtaa ttgctctaag agcttttaat gccttttact atactggata
   109321 tcctcacgct cagaagtttg ccgaccgaga gtgtgggggt ttttaatggt tgtttcttat
   109381 acagtttttc ttgcaattca tagcctcacg ctctgagtcg ccaaattgag agcatgagaa
   109441 agtaccagtt taaagagttg gcgctctccg tatggtcaaa ttgccctaaa tatgctataa
   109501 tctaggtata aatctttact aaaacctctt tgataatagc ttgcctgctt tgttaaattc
   109561 gttttagtgt tagtgtgaaa ggctctgcgg tgtggttatt gctaagcctt ttttgttgct
   109621 ctcacgcgct tctttggcgt gtttttttat ttctgaatgc catagccttg atttcttggt
   109681 aactcatatt caagccgatc atggctatta ccatatcctc aaatgcctgg tattgctcca
   109741 gctcgtcact ggtcaagcta tcaataccgt tatagccccc acgttcttcc cttaactgct
   109801 tagcgttcat gtcagttact gcttttagta gcaggttgtt catggtgcta tgcgcgtgct
   109861 tgggttttgc ctcccatgtc tctatactgt catgcaaggt ttttcttttt ggcttttcta
   109921 gcgccctctg catacggaac ttagaaagct cctcacgcat ttcaaagaat gctttgacca
   109981 ggttcttctt aaactctttt acgggttctg tatttcgtaa gtaagtgatc agcaaggttg
   110041 cttgttgctc attcaaaata tagtcccgta cattttgccc actttctgaa ggtgaaattt
   110101 taaattgcac ctttccgaaa ctctcgaagt cctctcgatg tttattcagc aaaatcttca
   110161 aatgtctgtg cttaacttct gcacactccg caacaatact gctcagtgta tacggctctt
   110221 tcttaccgtc catgtagact aattccattg gtttgctcct ttcttagatt tccttttgat
   110281 ttagttctat ttttttcgta ctatctccta aaaaatatcg tccagtttta cctgatacag
   110341 ttccgataac tctttaagta gctcaaaagg gattagcgta ctatcttttt cgtactttga
   110401 gatagtctga aaattcttgt tgaccttctt agccacttgg cgcaaagtaa aacctgcatt
   110461 tactcgacac gctcttagcg tccattgtgc catattctta tagctccttt caagattgat
   110521 aaaatcatgg tactattttt ttcgtacttt gtcaacgctg ttgttgaaaa attttatttt
   110581 tttcgtactt tgtctttttt gtgttataat caggttgtag aattaaagta agggagtttt
   110641 taacaatggc aaaaaatagc cctcaggatt taaagaatag agaatatttc tctaataatc
   110701 ttaaccgtgt tatgaaagaa aaaggtatca gacagataga cctgcataat gctttagaaa
   110761 ttcctaaaag tacaataact ggttatgtaa aaggtagatc aatgccaaca tctggcaatc
   110821 ttcaaaaact tgctgattat ttgggagtga aaaaatctga tcttgaccct cgcttttctg
   110881 acaaagatgt ttacaaagaa tttttatata tgttagataa acaattagac gaagaaaaat
   110941 acctcgtaaa aaatgtttca aaagataaaa tttttcagaa agtaaaagag agagagaaaa
   111001 gagacaagga aataattgaa ctagcaaaga gtaaaaattt cccaatcagt cctgaagagt
   111061 ttctcactac tatcactgaa tcattaaatg aatacaatcc caaagacaac tatgaagttt
   111121 taaatgccct tgcgctaaag acaagtaata tcctattctg gctagatatt gtatttcaaa
   111181 aaacaagtag tgaattctac atagtttttg aagataagga attcaaccaa gaatattaca
   111241 acaaattata taaaaagttt gaaaatctat ttgaagaaat taagtcttta gctcttcaag
   111301 aagctaagaa agataaagaa aatctagatg attttgcgtt actttggggt atagactaac
   111361 ccacgcgcca caatgttcaa caatcctgaa gcgcgtgtgc gaatgcgtgt gcgaatgcgt
   111421 gtgcgaataa tctactttca aaaaaacctt taatagcact gttagctaac taaaaataaa
   111481 ctatttttcc cgcgcgtgtg cgaatgcgtg tgcaaattga ttggagaaaa aatgagaaaa
   111541 tacgatatac caaaattgtt attatcaggg gagaaccaag gtgttgaatt caaagaagct
   111601 aaaaattctt tccctaaaga cggtatgaaa acaatttgtt ccttcgctaa tacaaataat
   111661 ggtctgttaa ttctaggtgt ctcagagaat acaaagaata aagattttta tatttctgga
   111721 gttaatgatc ccgataaagt actggacgaa ttatatagtt tacttaataa ccctaataaa
   111781 attaatagaa atgtgattaa tgaagaaagt gttgaagtcg taaatataaa aggaaaagag
   111841 attgtcatta tccctgttaa caaggtagac tacaaggata aacctatata tcttaatgac
   111901 aacatagcat ctacctattt tcgtcagggg actggtgatt ttaggtgttc acaagagcaa
   111961 atcaactcta tgttaagaga ttccgctaag gaaagttttg atagcacact tattcaggat
   112021 ttttctattt tagacttaga tacagaaaca ataaagctat atagagaaaa atttgataat
   112081 ataaatgcgg agcacccttt ttcaaagttg gataacgaac aatttttaat aaaaataaat
   112141 gctttacgaa gagatcgcaa ggacgataaa ataaagccaa cagttgctgg actattaatt
   112201 tttggtacac ataattcaat aaaagagttt attccacact ataacgtaga atatgttcta
   112261 aaagagtttt ctgaaaacaa tcgctttaaa gatcgtgtga tttatgatgg tacatggggg
   112321 gaagataatc tttttaattt cttttaccta gttattgaaa aattatatct aactttaaat
   112381 gacaactcta acattcaaga aaattctatg aatagaattg gaatttcaaa attacgaatt
   112441 gcaattcgtg aggcattcat taatagcctt attcatagcg actataaaag cgaaaaaggg
   112501 ataatgataa ttagatatcc cgacaggtat atattcacaa atggcggaac acttagaatt
   112561 gacataaagg acttttttag tggggcacat tctgatccaa gaaactactt aatacaagaa
   112621 atttttagat ttttaaattt atgtgaaaaa gcgggaactg gtatacccaa aataatggaa
   112681 gcagttaaag agagtcattt aaaatatccc aatttacgaa ctgaattaga ctcagttgaa
   112741 tttacattat gggatacttc ccttatagat aatctggata ttgataacga atatgagaaa
   112801 aagatattag agttaataat cgaacaccgt ttcgtaacaa gagaggcttt ggaagaaaaa
   112861 ctaaaaatcc acaaaaatac aattttaaaa tatttaaaaa aattagtgga aaaacaagct
   112921 atcgataaat tcaaatctgg tagacaatac gtatacttta ttacacaaaa ccaagatcct
   112981 gaatttcaaa aatataacca cattaatgct atgtattctt tactggaaga aataaaacga
   113041 aaataagggg gttctcgtag ctcctagcat gatataaaac ctttttgata atggcttgcc
   113101 tgctgatgta ttttagaaag gtttatcatc atgaaaataa ctgaagttat aaaaaaagac
   113161 ggtagcaaag tttatcgtgc taatgtatat ctaggagttg accaggtaac aggaaagaaa
   113221 gtaaaaacca aagtaacagg tcggacacaa aaggaagtta agcagaaagc caatcaagaa
   113281 aaaatagctt ttcaaaaagc aggatctacc agacaaaagg ctgttaccat aaaaaactat
   113341 caagaattgg caactctctg gttggaaagt tataagaata cggttaagcc aaacactcaa
   113401 ggcaatgtta aaaagctaat cgataatcat atattgccta tttttggggc ttacaagctc
   113461 gataagctca ctactccact tatccagtca attatcaacg aacttgctga caagactaat
   113521 agaggggaaa aagcggcttt tctacattat gacaagatac acgctttaaa caaacgtatc
   113581 ttacagtatg gcgtaaccat gcaggctata ccgtccaatc ctgcgcgtga tgttgtttta
   113641 cctcgtaaca ctcagaaagc aaagcggaaa aaagtaaagc actttgaaaa tcaagaacta
   113701 aaaaaatttc ttggttatct cgataattta gatactcata gatatcgtta ctactatgag
   113761 acaacactct ataagttcct attggctact ggttgccgta tcaatgaagc tttagctctt
   113821 tcctggtctg atattgactt agataatgcc gttgtgcata ttaccaaaac actaaatcgg
   113881 gatatagaaa tcaatagccc aaagtctaag gctagttatc gggatataga tatagatcaa
   113941 gcgactgtta gcatgctgaa gcagtacaaa ctacgccaaa ctaaagaggc ctggaagata
   114001 gggcaacgtg aacgcgtggt attttctgat ttcattcatg agtatcctag cagttcaaga
   114061 cttaaaagaa gattgcaaac acattttaag cgtgctgatg ttcctaacat tggatttcac
   114121 ggattccgtc acactcacgc tagtctcttg cttaactctg gaataccata caaggaactc
   114181 cagtaccgcc taggtcattc cactttatca atgaccatgg atatatatag tcacctctca
   114241 aaagagaacg caaaaaaagc agtatcattc tacgaaactg cactaaaagc actatagggg
   114301 gagcaaaaag gggagcaaat ttaaaaatca acatttcaag acaaagtaaa aatccaataa
   114361 caacggtgtc tttgtaagat tttatttgaa aaaagccgat tttgtagtat aatagtacag
   114421 tgtgaaaaaa tctgagaaag gataagggat atgaaacaag tttttctctc tacaacaact
   114481 gaatttaaag agatcgatac gcttgaaccg ggtacttgga tcaatctcgt caatccgact
   114541 caaaatgaat cactcgaaat cgccaacacc ttcgatattg atattgccga ccttcgagca
   114601 ccgctcgatg cggaagaaat gtctcgtatt accattgaag acgagtatac cctgattatc
   114661 gtagacgtgc cggtcacgga ggaaagaaat aaccgcacct actacgtaac catcccgctt
   114721 ggtattatca tcactgagga aaccattatc actacgtgtt tggaaccact acctgtcctt
   114781 gatgtcttta tcaaccgtcg attgcgtaat ttctatacct tcatgcgttc acgttttatc
   114841 tttcaaattc tttatcgcaa tgcagagctt tacctaacag cccttcgttc aatcgaccgt
   114901 aagagtgaac aaatcgaaag tcaactgcat caatcaactc gtaatgaaga attgattgag
   114961 ctcatggaat tggaaaaaac tatcgtctat ttcaaggcct ccctcaaaac aaatgagcgc
   115021 gtgattaaga aattgaccag ttcaaccagc aatatcaaga aataccttga ggacgaagac
   115081 ctgcttgaag acaccctgat tgaaacccaa caggccatcg agatggcaga tatttatgga
   115141 aacgtcttgc attctatgac agagaccttt gcctctatca tttctaacaa ccagaacaac
   115201 atcatgaaaa ccttggccct tgtgaccatc gtcatgtcca tcccaaccat ggtcttttct
   115261 gcctacggga tgaactttaa ggataatgaa attcccctaa acggagagcc aaatgccttc
   115321 tggttaatcg tctttatcgc ctttgctatg agtgtctcgc tcactctcta tctcatccat
   115381 aaaaaatggt tctaagagga gttcctatgt ctcagattga tctacaaaaa ttaactaaga
   115441 aaaaccaaga gtttgtccac attgctaccc aacaattcat caaagatggg aaaacagacg
   115501 ctgaaatcca gactattttt gaggaagtca ttccccaaat ccttgaggag caatctaaag
   115561 gtacaactgc ccgttcccta tacggcgcac caactcattg ggctcatagc ttcactgtca
   115621 aagagcagta cgaaaaagag catccaaaag aaaatgatga tccaaaactg atgattatgg
   115681 actcagctct tttcatcact agcctctttg cccttgtcag cgccctcaca accttctttg
   115741 cggcagatca agctttcggc tatggattga ttactcttct attagttgga ctggttggtg
   115801 gatttgcctt ctacttgatg tactactttg tttaccaata ctatggacca gatatggatc
   115861 gcagtcaacg tccacctttc tggaaatctg tactagttat cctagcttct atgttccttt
   115921 ggttgcttgt cttctttgca acaagcttcc taccagctag ccttaaccca gtactggatc
   115981 cattgccact agctattatt ggagcagccc tcctagccct tcgcttctat ctcaagaaac
   116041 gcttgaatat ccgtagtgca agtgcaggac caacacgcta tcaagaataa gaaaacgata
   116101 aaagcaactg caggtgcggt tgctttttca cttacttttt tgagttatac tcaatgaaaa
   116161 tcaaagagca aactaggaag ctagctgcag gttgctcaaa gcacagcttt gaggttgcaa
   116221 ataaaactga cgtggtttga agagattttc gaagagtatt aaaagtattc ttctgaaatc
   116281 ccacatagct ttctcttata ttttgtgata aaataggctc aatctatttc taggaggatg
   116341 agatatggtt tctactattg gtattgttag tttatctagt ggcattatcg gagaggattt
   116401 tgtcaaacac gaagtggact tgggtatcca acgtctcaag gttctgggac tcaatcccat
   116461 ctttttgccc cattcgttaa aaggattaga ctttatcaag gaccatcctg aagctcgtgc
   116521 agaggatttg attcatgcct tttctgatga tagcatcgac atgatcctat gtgccatcgg
   116581 tggagacgat acctatcgct tgctacctta tctttttgaa aatgaccaac tccaaaaggt
   116641 tatcaaacaa aaaatttttc ttggcttctc ggatacaacc atgaaccacc tcatgttgca
   116701 taaattagga atcaagactt tttatggtca atccttttta gcagacattt gtgaattaga
   116761 caaagaaatg ctagcctata gccttcacta ctttaaagaa ttgattgaga cgggaagaat
   116821 ttcagaaatc cgccctagtg acgtttggta tgaggaacga actgatttta gtcccacggc
   116881 cctggaaaca cctcgtgtca gtcatacaaa tacaggtttt gacttgttgc aaggaagtgc
   116941 tcagttcgag gggaaaatcc tcggtggttg cctcgaatcc ctctacgata tctttgacaa
   117001 ctctcgatac gcagatagca cggagctctg ccaaaaatac aaacttttcc ctgacttgtc
   117061 agactgggaa gggaaaatcc tcttgctcga aacaagcgaa gaaaagccta agccagaaga
   117121 cttcaaaaag atgttgctaa ctttaaagga cactggcata ttcgcggtca tcaatggact
   117181 cttggtcgga aaacctatgg atgaaacttt ccatgacgac tataaagagg cactattgga
   117241 tatcattgac agcaatatcc cgattgtcta taatctgaat gtcggccacg caactccaag
   117301 agccattgtt ccctttggcg ttcacgccta tgtagatgca caggaacaag tcattcgctt
   117361 tgactataac aaaaaataaa tagtttctct atttttgtgc ttttgtattg gttttcgtta
   117421 caatttgtat ctgaatttat tgcatttcgc taatttctat ggtatccttt tgaaggaggt
   117481 gtatatgaca aaacaaaaaa ttaatcgaat cgtaggttct attggtgcct ttattggaat
   117541 tatagtattt attgcctaca tacctcaaat tatcgctaat ttacaaggaa ataaagctca
   117601 accatttcaa cctttatcag ctgctatatc ttgcttaatc tgggttattt atggatggac
   117661 aaaggaacct aagaaggatt ggatactaat cattccaaat tcagctggtg ttattttagg
   117721 tggaatcact tttttgactt cactctaaca aatctaatag tatatataaa aagctgggaa
   117781 aaatttctca gcttttttct atattctcag atatgctagt tacctgtaca cactaattcc
   117841 tgcttttcca ttcacaatca ttctcgtggt catcaactag ccctgcagcc tgtagaaaag
   117901 acaagacagc gactggtcct gtgaacttga agcctcgttt tttgagatct ttggctaatt
   117961 tctcagacaa aggtgtttta gctggggctt ggcggtaatc gggaacatcg ttaacaatcg
   118021 ttttcccctc aacaaaagac caaagatagg catcaaaaga gccatggtct tcctgtagtc
   118081 gtagaaaggc ttgggcgtta gcgcgtgtag caaaaatctt ggctctattt cggatgatgg
   118141 ctggattatc cagcaagtct tccaattcag tatcggtcat ttctgcgacc gcttgaattt
   118201 gatagccata aaatgcttct cggaaagctt gacgtttgtt gagcaccgtt tcccaagaca
   118261 gaccatgttg aggcggtaag tttgctagtc aaggagtaaa acgacgaaga ttagcattta
   118321 cttccgccca tgcgatagct gtccgtgatt gacaagtgct agcacgcaga cagaacggag
   118381 atagcgaacc gctgagtgtg tcgctctgct cgtaaaagct tagaaacctt tgaacgaaag
   118441 ggataatgaa agccttgatt gcaaggcttt ttgctttatg gtgggtaagt atcagagtga
   118501 gaaaattttt ggaatgagta gaagtgatag ctagaaatta tcagtttcta tttccattta
   118561 ccctgtgggt acgtgtttgt ttccattgac aaggagtttg tgggaataga aatgtaccca
   118621 ccttgtttga atcaagtgaa gtgtagttga aggaaatctg ttgaaagcaa tacttcattt
   118681 taccgaataa gtaataattt aggcaacttc aaatcgatta aaaaaaacta ttttaaaggt
   118741 taagagtaga caaaaattgt ccactctttt ttgcaaactc aatttatcaa taaatgaaat
   118801 gagggaatgt aaaatgaaat attttgaggt tgagttagaa aatcctgatg aatttttaaa
   118861 actacaaaca gaagattttg tgaaagctaa tcgcttgcta ctaaggaaga taatccagag
   118921 cgttacagtc tatgaagaaa acttcgtcat atcctttaaa tctggcatcg aattggaagt
   118981 atgagtctca ttccataact tttatattga acatatcatc ttgttgtgtt atactataaa
   119041 ttgatataaa caaagatgta ggaggaaccg aaactatgac agcctcaatg cgtttaagat
   119101 aagctggcaa taaaaaaagc agaatctata cccgatgata ggcttttttg ttgtgcttat
   119161 ttatacgata ttgagcattc attagttacg gtgaggatat tggttattta actatacctt
   119221 tatttaacta tgtctttaat atgaatgttt ccaaattgta tgtatgcaga ccaaaagcca
   119281 cattgtgggg tttggcctgc attttttatt gcctagaatg ctattcaaaa tagaaattca
   119341 agcaaaataa tatgcaggag ataatataaa tggaaaaata caacaattgg aaacgaaaat
   119401 tttatgcaat atgggcaggg caagcagtat cattaatcac tagtgccatc ctgcaaatgg
   119461 cgattatttt ttaccttaca gaaaaaacag gatctgcgat ggtcttgtct atggcttcat
   119521 tagtaggttt tttaccctat gcgattttgg gacctgccat tggtgtgcta gtggatcgtc
   119581 atgataggaa gaagataatg attggtgccg atttaattat cgcagcagct ggtgcagtgc
   119641 ttgctattgt tgcattctgt atggagctac ctgtctggat gattatgata gtattgttta
   119701 tccgtagcat tggaacagct tttcataccc cagcactcaa tgcggttaca ccacttttag
   119761 taccagaaga acagctaacg aaatgcgcag gctatagtca gtctttgcag tctataagct
   119821 atattgttag tccggcagtt gcagcactct tatactccgt ttgggattta aatgctatta
   119881 ttgccatcga cgtattgggt gctgtgattg catctattac ggtagcaatt gtacgtatac
   119941 ctaagctggg taatcaagtg caaagtttag aaccaaattt cataagggag atgaaagaag
   120001 gagttgtggt tctgagacaa aacaaaggat tgtttgcctt attactctta ggaacactat
   120061 atacttttgt ttatatgcca atcaatgcac tatttccttt aataagcatg gaacacttta
   120121 atggaacgcc tgtgcatatt tctattacgg aaatttcctt tgcatttggg atgctagcag
   120181 gaggcttatt attaggaaga ttagggggct tcgaaaagca tgtattacta ataacaagtt
   120241 cattttttat aatggggacc agtttagccg tttcgggaat acttcctcca aatggatttg
   120301 taatattcgt agtttgctgt gcaataatgg ggctttcggt gccattttat agcggtgtgc
   120361 aaacagctct ttttcaggag aaaattaagc ctgaatattt aggacgtgta ttttctttga
   120421 tcggaagtat catgtcactt gctatgccaa ttgggttaat tctttctgga ttctttgctg
   120481 ataaaatcgg tgtaaatcat tggtttttac tatcaggtat tttaattatt ggcattgcta
   120541 tagtttgcca aatgataact gaggttagaa aattagattt aaaataaaca atattggagg
   120601 aaatgttatg gaattaatat taaaagcaaa agacattcgt gtggaattca aaggacgcga
   120661 tgttttagat ataaatgaat tagaagtata tgattatgac cgtattggtt tagtaggagc
   120721 aaatggtgct ggaaaaagca ctttactcag ggtactttta ggagaattaa ctcccccagg
   120781 atgtaaaatg aatcgtctgg gtgaacttgc ctatattccc cagttggacg aagtaactct
   120841 gcaggaggaa aaagattttg cacttgtagg caagctaggt gttgagcaat taaatataca
   120901 gactatgagc ggtggtgaag aaacaaggct taaaatagca caggccttat cggcacaggt
   120961 tcatggtatt ttagcggatg aacctacgag ccatttagac cgtgaaggaa ttgattttct
   121021 aataggacag ctaaaatatt ttacaggtgc actgttagtt attagccatg accgctattt
   121081 tcttgatgaa atagtagata aaatatggga actgaaagat ggcaaaatca ctgagtattg
   121141 gggaaactat tctgattatc ttcgtcagaa agaggaagaa cgtaagagcc aagctgcaga
   121201 atacgaacaa tttattgcgg aacgtgcccg attggaaagg gctgcggagg aaaagcgaaa
   121261 acaggctcgt aaaatagaac agaaggcaaa aggttcttca aagaaaaaaa gtactgaaga
   121321 cggagggcgt ttagctcatc aaaaatcaat aggaagtaag gaaaaaaaga tgtataatgc
   121381 tgctaaaacc ctagagcaca ggattgcggc cttaggaaaa gtagaagctc cggaaggcat
   121441 tcgcagaatt cgtttcaggc aaagtaaagc attggagctc cataatccat accctatagt
   121501 cggtgcagaa attaataaag tatttgggga taaggctctg tttgaaaatg catcttttca
   121561 aattccgtta ggagcaaaag tggcgttaac tggtggtaat ggaatcggaa aaacaacttt
   121621 aatccaaatg atcttaaacc atgaagaagg aatttctatt tcgcctaagg caaaaatagg
   121681 ttactttgca cagaatggtt acaagtacaa cagtaatcag aatgttatgg agtttatgca
   121741 gaaggattgt gactacaata tatcagaaat tcgttcagtg ctagcatcta tggggttcaa
   121801 acagaacgat attggaaaaa gtttatctgt tttaagcggt ggagaaatta taaaattgtt
   121861 gcttgctaaa atgctcatgg gtagatataa catcctaata atggatgaac ccagtaactt
   121921 ccttgacata ccaagtttag aggctttgga aatactaatg aaggagtaca ccggaactat
   121981 cgtgtttatc acccacgata aacgattact cgaaaatgta gcagatgtag tttatgaaat
   122041 tagagataag aaaataaatc tgaaacatta aatttaaggt agtcgctggt cagtatagtc
   122101 tgttctggtt ggcgactcca ttgttaaaga gtataaagac tttagatttt atgaatatta
   122161 aaaataggaa cagtcaattg aactgctcct atttttctgc taaatatatt gtagttttct
   122221 tatatgtata atgatagatt agcggattct catctacggt acttacttca aatatgaaga
   122281 agtgatcgcg gttatctctg gacttttcct tattgaggac aaagtaattc ttacgtgaag
   122341 tcgccattgt ttttaggata tcatcagtta ggaaggtcaa tggaatattc atgttagagt
   122401 agcggtagaa gtcacgttca aaatcttggt agctctcgct ataatagtcc atttgtaggt
   122461 gattacgctg aaactcaagc tgattcatag agcacctcct cgacaagttc aatactaata
   122521 atgtctttta atttcaaatt gatgtgacct gttgtagttt ttatcaaaat gaaatctttg
   122581 gtcagacttg gtattgttcc agtgtaggaa acacgcttgt ttttttcaat cacttgaatg
   122641 cgtgtgcgta gctgcccggc gtatacttga ctgaggagta ataatttctt ctctagtgat
   122701 aagtcagaca tgtacgttac tttgtttgta tcatcagaga gtgctgatgc atgttcagat
   122761 aggaaaaagc ccatccattt ttgcatcttt gtatcctggt actctcttgc tgattgaaat
   122821 ggtaaatatg aacggtcaat catatcaaat cctttctatg cagaggcaag ggtattttta
   122881 tcaaattgaa tcgtaaaacc ttgaattccc ccacctgtgt aacattcttt aaagcgattg
   122941 attacctcag tatagattat cacagatgag cttgttggct taatgctaaa tgtaaattcc
   123001 aatggtaatc ggttttcaga tttagcatgt actagtcgta tcgatatttc agttgttttg
   123061 agttttctct gacgaagttt tgaagttgct gtttcaacga ttccatgtaa aaatctttca
   123121 agcatttcaa tatcattaca tcctttgcta cggatttctg aaaattgtac tgtatttttt
   123181 tcttgtttca ttttaatccc tccaatccac ccgcggaatg accaccgata agtttactgc
   123241 gttcaatatt tctggaacct tcagttagga cggttccttt ttgtatggct aaaaaaccaa
   123301 actgttctct gacaacatca atagctgtct gaagtctatt atctttttca atttgttcta
   123361 catcatcaaa gagtgatagt agagtatagc tttcatctac gaagccacta taagatacac
   123421 caatttgtct cactgcacca gaggtgtatt ttttcggaat aatacaagta catgactcac
   123481 cattgttttg gggagatttg cgggttcaat tttattctga gcatttatag attttttcat
   123541 ctcagtccta gaatagccaa tatgaataga aacgacagta gtcaatacta gggctactgt
   123601 tccgttccac agtatcattt aaaaatcatt ttcacaccct ttcgtctatt agtatagaag
   123661 aaagctctca gcacagcctg ataggtttcc atacacaaca actcaaacaa tgcttggtca
   123721 tcatggaggg gttgacccca ctcctcatca tgataggcaa tgtagagcgg attggtcacc
   123781 ttgacccacg aacaacgttt tgtcatgctc tgctcctatt tgaccaacat tttaagggcc
   123841 gacttgatat agttctcagc tgtatctgtc gttccttcaa agaatttctt gattttcttg
   123901 agttcggtcg ccttgtatcc cagtgccaac atggcttcca tggcttcttc caattcttgg
   123961 ttttcagcgc ttgcttgcac tgcgacctta gcaggaaggt catctccagc aactactacc
   124021 ttgccttcca agtccagcac catctgctgg gctgttttct tgccaatttt agggaacttg
   124081 gtcaagtagg taatattctt ggtttcgatg gcttgaacca agccagcatt gtcatcagca
   124141 gcgataatag caagagctga tacaggacca atcccagaga ccgaaatcag actaagaaag
   124201 agctttttct catcctctga gcgaaatcca taaagcaaat gggcgtcctc acgcacaacc
   124261 tgatgcacat aaatctgagc ctcctgatta acctgacctg aataggcata aggattggcc
   124321 acatgcagga tataaccaat accattggtt tcaagaacaa tgtatttggc agtaattttg
   124381 gtaatgattc cttttaaata tgcgtacata gtgttccttc tctcttattt cgtttatcta
   124441 gtatatcata ttttctttat ccgaggagcg agaatcgatt atcacaaata cagtatatca
   124501 aaaacaatcg gtatttatct gttgacatat tcaaaattaa gtactataat catctgtaat
   124561 tgaataacta tcttcagggc agggtgcaat tccctaccgg tggtatagcc cacgagccga
   124621 aaggcatgat ttggtgaaat tccaaagccg acagtatagt ctggatgaaa gaagataaaa
   124681 gtatatttgt gctttttgcg tgctctgaaa tgattacttg tcatttcaga gcatttttgt
   124741 taatcgcata agttttcttt tgtatgcctt gagtagtccc ctattcaagg tatatttttt
   124801 tggaggtagt gagatgagcg attcaaaata tatgaaatta gcaataaaac tggcacaaaa
   124861 aggggctggt tacgtcaatc ccaatcctat ggttggcgca attattgtaa aagataatca
   124921 cattatcgga caaggttatc atgagttttt tggtggccca catgctgaga gaaatgctct
   124981 taaaaactgt agaaaatccc ctgtcggagc gacgctttat gtaacacttg aaccctgttg
   125041 tcacttcggg aaaacacctc cctgtataga tgctataatc gatagtggta ttacaagagt
   125101 agtcattgga agcctagact gtaatcctat tgtatctgga aaaggagtaa agatacttga
   125161 ggaaaataat cttcaagtta ctgttggaat tttagaaaat gagtgtctta acttaataaa
   125221 aagttttaga aagtatatta cccagcatgt accctatgtt tttatgaaat atgcaatgtc
   125281 aatggatgga aaaatagcca ctaaaacaaa tcaatccaaa tggattactg aagaagaagc
   125341 aagaaagcat gtgcatcagt tacgacacta tgttagtgca attatggtgg gagtcaatac
   125401 tgttattcaa gacgatcctt tgctgacatg tagattggag gaagggaaaa atcctatccg
   125461 tatcatatgc gatacacatt tacgaactcc tcttacctct aaaatcgtaa aaacagcaaa
   125521 tgatattaaa acttacattg ccacttcctc tgaagacaaa aataaaatga agctatatca
   125581 aaatcatggc tgtgaaatac tttccataaa gaaaaaaggc aatcatatag acttatcgag
   125641 tttaatgcaa catctaggaa acatgcagat tgatagccta gttctagaag ggggcagtct
   125701 aatgaattgg agtgctttgg aacaacaaat tgttgatgag ctgaaaatat atattgcacc
   125761 aaaaattttt ggaggcagtg ccaagtttcc tgtcggaggt gaaggcattt ctttgccaaa
   125821 tgacgctatt agattgaaac cttatgcttt ttctcaaata ggaaatgact atctcataga
   125881 aagtgaagtg atttatccat gttcacagga ataattgaag aaatcggaaa agttgaaaga
   125941 atacagaaag actctcgtaa ttgtaaacta tcaattaaag cctcaaaaat attaacggat
   126001 atccatttag gcgatagtat agcagtaaat ggtatctgtc ttacagttac tcatttcaat
   126061 catcaatcct ttacagttga tgtaatgaat gaaacatgga gtcgaacagc tcttactcta
   126121 ttaaaacatg gaagtgaggt gaatctagaa agagccttat ctgtcaacgg tcgacttggg
   126181 gggcacgtcg ttacaggaca cattgatggt acaggaaaaa tctcgtcaat aaaaaaagat
   126241 gataatgctg tatggtatca aatcaacaca caaaaagaaa ttttagattt aatagttgaa
   126301 aaaggatcta ttacaattga cggcattagt ctgactgtcg ctaaagtctc caaagtaaac
   126361 ttttcagtat ctgttatccc tcataccttg gaacaaacca ttcttaaaag tcaacaagtc
   126421 gggaatacag taaatcttga aaatgatatc ttaggtaaat atgtgcaaaa attgatggat
   126481 aactctccaa aattagaaat atctaaggaa ctattatatc aaaatggatt ttagcagaaa
   126541 ggataatcag tcaatggaat atcgaaaaat acaagaagca ttagaagcat tgcagaaggg
   126601 acgacttgtt cttgttatag acgacaagga tagagaaaat gaaggagact taatttgttc
   126661 tgcacaagca gctacaacag aaaatgttaa ttttatggct acttatgcca aaggattaat
   126721 ttgtatgcct atgagcgaaa gtttagctaa tcaattaatg ctttcaccta tggttgaaaa
   126781 caatacagat aatcataaga ctgcttttac agtttcaatt gattataaag aaacgaccac
   126841 aggtatttct gccgaggaga gaggactgac cgcacgtatg tgtgtagctg aagatataac
   126901 accctctgat tttcgcaggc caggacacat gtttccttta attgcaaaaa aaggtggtgt
   126961 tctagaaaga aatggacaca cagaagcaac tgttgattta ttaaaattag ctggactaaa
   127021 agagtgtggc ctatgttgtg aaataatgaa tcatgatggc aaaatgatga gaacagatga
   127081 tttaattcag ttctcgaaga aacacaacat tccactaatt accatcaaag aattacaaga
   127141 atatagaaaa gtatatgatc agctggtaga acgagtttca actgtcaata tgcctactag
   127201 atacggtaat ttcaaagcaa ttagctatat agataaacta aatggggaac atcatcttgc
   127261 tcttattatg ggaaacatag aggatgaagc caatgtatta tgtcgggtcc actccgaatg
   127321 tttaacagga gatgttttag gctctttacg ttgcgattgt ggacagcaat tcgataaagc
   127381 tatgaaaatg attgttgaga atggttcggg tgtcttactt tacttgcgac aggagggacg
   127441 aggaattgga cttatcaata aattaaaagc ctatcattta caagatcaag gcatggatac
   127501 gcttgatgcc aatcttgcat taggctttga aggtgattta agagaatatc atattggagc
   127561 acaaatgctt aaagatctgg gacttcagtc acttcattta ctgacaaata atcctgacaa
   127621 ggttgaacag ttagaaaaat atggaattac catttccagt agaatatcaa tcgaaataga
   127681 agccaatcct tacgatagtt tttatttaga aacaaagaaa aatcgaatgg gtcacatttt
   127741 aaatatggag gaaaaataaa tgaacactta tgaaggtaat ttagtagcaa acaatattaa
   127801 aataggtatt gttgtagcga gatttaatga atttataact tcaaaattat tatctggagc
   127861 actagataat ctcaaaagag agaatgtaaa cgagaaagat atcgaggtag cctgggttcc
   127921 aggagctttt gaaataccac tgattgcatc aaaaatggca aaaagtaaaa aatatgatgc
   127981 aattatctgc ttgggagctg tcattagagg gaatacaagt cattatgatt atgtatgtag
   128041 cgaggtatct aagggaatcg cccaaatcag tttaaatagc gaaattcctg ttatgtttgg
   128101 tgtgctaacg acagatacaa ttgaacaagc catagaacga gctggtacta aagcaggaaa
   128161 taagggttct gagtgtgcac aaggagctat tgaaatggtc aacctaattc gtacattaga
   128221 cgcatagaac agactctact tttagacgaa taaagaaact tggcaaaatc gcaatttaat
   128281 actctgtgaa aatcatagag caaactagga aaccagtcgc agagtggtca aacacaactt
   128341 cgatgttaca gacaaaactg gcaaaattag ctcaaaacac tgttttgaga ttactgataa
   128401 aactgacgtg gtttaaaaag agtttcgaaa agaattagga aaacatgaag taaatatttc
   128461 tatgataaaa cgcataaaat caaggttttt gaacacctga ttttatgcgt ttttctgatt
   128521 ttgaaaattt ttcccagact tttttatact tttaatattt ccccaactca cggagactgg
   128581 tgtgattttc ctgaatacgt cggaacatct tttccatatc cgacttggta aaatgcacca
   128641 aaacaggacg tccgtgagga cagttatagg gattgtcaca ttgagaaagc tgatagagga
   128701 gttgtctagc tgaatgatca tcaatacgat gattggcctt gatagatcgc ttgcaagaca
   128761 tcatgatagc cagctctgct cggtatttct tgatagaaac tttcttggtc aaaaggagca
   128821 tgtcgcacat ctcatagatg cctgattcaa tctcttcttc tgccatccaa ataggatgtt
   128881 cacgtagaat aaattgattt tctccgtact ctgctagaaa gacgcccact tcctctaaga
   128941 gaggcattct ttccttgaga cgcagggcat catccgcagg aaattcaaag atatagggca
   129001 ctaggagttg ctgctgactc tggtcaacat tgccaatgct ttcacggtac tcctcgtact
   129061 tgacccgttc ctgagcagcg tgctgatcta tgatgtaaag tccatctcgc ccttgggcaa
   129121 agagataagt cccgtgcatt tgtccgaaaa actccaactc tgggaagctg gatgcttctt
   129181 ctcgctccag tttgtcataa gccttatcga tgctagcaag atctaactct ggatggtcta
   129241 gctggtcgta gttagcaggc tttctctctg caaaatgcag ttttgctggc ttggtcaatc
   129301 ggtccaaggt ttccttggca aacagggtca aatcctgccc ttcatcagtc aattctacct
   129361 gataatcagc tacttcagtt tgactaggtc ttgacggctc agttttctca tagtagagcg
   129421 tattttcttt gagtgggaga atagtttgct ccaccttctc acgattgcgc acggtcgatt
   129481 tggcaagatt ttccaaggca tctggaatca aggtttgttc cttgagacta tttgcaatag
   129541 cttctgaaac cagggtcatc agttcttttt ccttggaaat ccgcacctct tgcttagttg
   129601 gatgcacatt gacatccgct agataagggt cgatatggat gtgaatgaca gccagtggaa
   129661 aacgtccaac cataagcttg cttccgaaac catccaaaat agcacgattg agcaggaagt
   129721 tcttgatata acgaccattg atgaagaggc tgatataatt gcggttagcc cgagtcaact
   129781 caggcaagga cacaaaacct gaaatttcga aatctaggtc agagttctca atttcaatca
   129841 tcttcttggc actgaccaaa ccgtaaatcc ctgcgattgc ttggcgcaat tgaccagtcc
   129901 ctgctgtccg cgtcatttcc ttgccatcac taatcaagct aaaagaaatc tcaggatggg
   129961 ccaagcccag acggttgaca atatcaatga tatgagacaa ctccgcttgc tggctcttca
   130021 tatacttgag acgggcaggc gtgttgaaaa agagatcctc cacacaaacc ttggttccca
   130081 caggactagt cgctgggatg acttcctcaa cttcaccccc gcgcgcgact aacttggttc
   130141 catgactagc accatccacc gccgttaaca gagtcaagac actaacagac gcaatagaag
   130201 gcaaggcttc accacgaaaa ccaagcgtcc gaatccgaaa gagatctgct tgatttttta
   130261 tcttactggt cgcatggcga cgcagggcca actccacctc atcgtgggca attccatgac
   130321 cgttatccgt gatttgaacc ttcttgagac cagcttcctc aatctcaatg ataatctgac
   130381 tagagcccgc gtcaatggca ttttctacca actctttgac cacactggca ggacgttcaa
   130441 tgacctctcc agccgcgatt tggtttgcca gcatctctgg caattcaata atatgagaca
   130501 tctttcagcc cctttctgta tctattttcc tagaaattaa ttagtgctat tataccatat
   130561 ttcagaaaga acagaaaagc tccaccacat aggagcccaa tccctccaca tagacaaagt
   130621 cccttgccag agggagtaaa atagtggtat actcaataaa aatcaaagag caaactagaa
   130681 agctaggcgc agacagttca aaacactgtt ttgaggttgt agataaaact gacaaagtca
   130741 acaactatcc tatggcaaga cgacgctgac gtggtttgaa gagatttttg aagagtatta
   130801 ataaaggtgt acaagaagtg agattaattt tgtatgaaaa acaaggagag aaatttatga
   130861 aagtagaact acagattagt gagacttacg aggaggaaaa gctgattgtc caagcacctc
   130921 agccgacaga taaagtccag aaagtcatcg agttcgcaga aaatctggac caaagagaaa
   130981 aaatcaaagg gaaaatcgat gatcaggtct atctagttga gattggcaag attcagcgct
   131041 tctatataga gaatcggaag gttctagcag aaaccgcgag tcagacctac agcattgatt
   131101 tgcgactcta tcaggttctt aaactcttgc caagcaattt tatccaaatt tcccaatcag
   131161 aaatcatcaa tatcgattcc atctctcacc tcaagctcac gccaaacggt ctggtagaaa
   131221 ttttcttaaa aaacgaaagc ttcacctact cttcacgccg ttatctaaaa accatcaagg
   131281 agaaattaga actatgaaaa aacaagtatt tcacgatgca gctgccggtg ttcttatcgg
   131341 cctcatcctc tccatcctct tttcactcat ttatgcacca aatacctacg caccactaaa
   131401 tccctactct ctcatcggcc aagtgatgga tcagcatcag gttcacggtg ccctggtctt
   131461 gctctactgc acacttatct gggcagccat cggtatgctc ttcaactttg gcaaccgctt
   131521 attcagccgt gactggagca tgcttcgtgc cactctgact catttcttcc ttatgctggc
   131581 tggctttgtc ccactagcaa ctcttgctgg ttggttccct ttccactgga ttttctacct
   131641 ccagctcatt atcgagtttg cgattgtcta tctcataatc tgggctattc tctataaaag
   131701 agaggctaaa aaagtagatc acatcaatca actcttggag catagaaaat aggaacctca
   131761 taataaacaa atccgagaaa gaaacttctc ggtttttctt tatcctgctg caccttacta
   131821 tagtgaaatg aaataagaac aggataaatc gatcaggaca gtcaaatcga tttctaacaa
   131881 tgttttagaa gcaaaggtgt actattctag tttcaatatg ctatatcata acagttattt
   131941 cagattttct ttgtaaattt tctatctttt ttcaaaatat tcttgcattt ttccaaaatt
   132001 ttttgtagaa tatagattac atatacagat tattctgaaa attcaaaaag gagtatttat
   132061 catgtcgcaa gctatttcct taaatcaatc aacctgggca agcaagctaa aagcaatggg
   132121 acctggaatc ctaatggcaa ctgccgctgt tggaggttcc cacattgtat cctcaactca
   132181 agctggcggt tcttacggtt ggtctctact tctcttggtc atcttagcca atgtctttaa
   132241 atatccattt ttccgttttg gtgctgaata cacagctgat actggaaaga ctttggttga
   132301 aggttatgcc gaaaaaggaa aactctatct ctggattttc tttatcctca atgtcttttc
   132361 ggctatggtc aacacggctg gtgttgccat tctgtgctca gctatcatcg ccagtgcctt
   132421 cccaatgatt ggacttagca ttactcagtg gtccctcatt ctcgttgcaa tcatttgggc
   132481 tatgctactc tttggaggct acaaactttt agacggcatg gtcaaatgga ttatgtctgc
   132541 cttaaccatt gcgactgttc ttgcagttat cattgcggcg gtcaagcatc cagaatacag
   132601 ttctgatttt gtcgagaaga caccttggca aatggcagct ctgcccttca tcgtctccct
   132661 cctaggatgg atgccggctc ctattgaaat ttcagccatc aattcacttt ggtcagctga
   132721 aaagagaaag accgtcaact ttaacacaga agacgctctg tttgacttta acactggtta
   132781 tattggaaca gctatcctag ccgtcttctt tgtggcactg ggagcactga ttcagtatcc
   132841 tacagggcag gcggttgaag ctgcttcagc caaatacatc tctcaattcg tgggcatgta
   132901 tgcctctgtt cttggcgaat ggtcccgtta cttgattacc tttattgcct tcctctgtat
   132961 ctttggaaca gttataactg ttatcgatgg ctattctcgc gttaatcagg aatctctccg
   133021 actgctaatc agtcaaaaag aggacaatcg taaatctttg aacatctgga tgaccatcac
   133081 tgctatcatc ggtatcgtca ttatcaagtt cttcgctggt caggtttcaa ccatgctccg
   133141 ctttgccatg attggatctt tcctgacaac acctttcttt gctcttttga attacgcctt
   133201 ggtaacgcgt gaaaacaaaa atcttccttc ttggctcaaa caccttgcca ttgcgggatt
   133261 gattttcctc tttggcttcg ccatcttctt tatctacgca ctcgcaatcg gaaaagcagg
   133321 gtaagggaca agcgcgagat gaagataagg tttcatttca agagaaaatt cagcaaatat
   133381 ttctatgata aaaagcataa gaacaaggtt ttgaagacct gaacttatgc ttttttacgt
   133441 tcttaaaggc tgtttatact caaaaaacag ttgaacaact tcaaccacct cttataagaa
   133501 ctttataccc caattattca cccctaatct aaaaaccatc cagaatcctt gccttagctt
   133561 agatcctgga tggtttcttt t
//
LOCUS       DAVAGB010000002       102331 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVAGB010000002 DAVAGB010000000
VERSION     DAVAGB010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 102331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 102331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..102331
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.002"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="VQO19_000152"
     CDS             complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="VQO19_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HET1348473.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
     gene            complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="VQO19_000153"
     CDS             complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="VQO19_000153"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HET1348474.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="VQO19_000154"
     CDS             complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="VQO19_000154"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HET1348475.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3790..5058)
                     /locus_tag="VQO19_000155"
     CDS             complement(3790..5058)
                     /locus_tag="VQO19_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HET1348476.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGELTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5178..5546)
                     /locus_tag="VQO19_000156"
     CDS             complement(5178..5546)
                     /locus_tag="VQO19_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HET1348477.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5539..5805)
                     /locus_tag="VQO19_000157"
     CDS             complement(5539..5805)
                     /locus_tag="VQO19_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HET1348478.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5863..9372)
                     /gene="mfd"
                     /locus_tag="VQO19_000158"
     CDS             complement(5863..9372)
                     /gene="mfd"
                     /locus_tag="VQO19_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HET1348479.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLMSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFVFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTEFGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKELMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            complement(9373..9942)
                     /locus_tag="VQO19_000159"
     CDS             complement(9373..9942)
                     /locus_tag="VQO19_000159"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HET1348480.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDEYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10013..11128)
                     /gene="ychF"
                     /locus_tag="VQO19_000160"
     CDS             complement(10013..11128)
                     /gene="ychF"
                     /locus_tag="VQO19_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HET1348481.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11212..11406)
                     /locus_tag="VQO19_000161"
     CDS             complement(11212..11406)
                     /locus_tag="VQO19_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HET1348482.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11471..12607)
                     /gene="dnaN"
                     /locus_tag="VQO19_000162"
     CDS             complement(11471..12607)
                     /gene="dnaN"
                     /locus_tag="VQO19_000162"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HET1348483.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12766..14127)
                     /gene="dnaA"
                     /locus_tag="VQO19_000163"
     CDS             complement(12766..14127)
                     /gene="dnaA"
                     /locus_tag="VQO19_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HET1348484.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14340..15098)
                     /locus_tag="VQO19_000164"
     CDS             complement(14340..15098)
                     /locus_tag="VQO19_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HET1348485.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLETLLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15156..16337)
                     /locus_tag="VQO19_000165"
     CDS             complement(15156..16337)
                     /locus_tag="VQO19_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET1348486.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16520..16999
                     /gene="rlmH"
                     /locus_tag="VQO19_000166"
     CDS             16520..16999
                     /gene="rlmH"
                     /locus_tag="VQO19_000166"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HET1348487.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17043..17116
                     /locus_tag="VQO19_000167"
     tRNA            17043..17116
                     /locus_tag="VQO19_000167"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17077..17079,aa:Arg,seq:tct)
     gene            17281..17406
                     /gene="comC"
                     /locus_tag="VQO19_000168"
     CDS             17281..17406
                     /gene="comC"
                     /locus_tag="VQO19_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HET1348488.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17427..18752
                     /locus_tag="VQO19_000169"
     CDS             17427..18752
                     /locus_tag="VQO19_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET1348489.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18749..19501
                     /locus_tag="VQO19_000170"
     CDS             18749..19501
                     /locus_tag="VQO19_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET1348490.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19553..19624
                     /locus_tag="VQO19_000171"
     tRNA            19553..19624
                     /locus_tag="VQO19_000171"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19586..19588,aa:Glu,seq:ttc)
     gene            19630..19703
                     /locus_tag="VQO19_000172"
     tRNA            19630..19703
                     /locus_tag="VQO19_000172"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19664..19666,aa:Asn,seq:gtt)
     gene            complement(19744..20286)
                     /locus_tag="VQO19_000173"
     CDS             complement(19744..20286)
                     /locus_tag="VQO19_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HET1348491.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20393..21570
                     /locus_tag="VQO19_000174"
                     /pseudo
     CDS             20393..21570
                     /locus_tag="VQO19_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
     gene            complement(21600..24152)
                     /locus_tag="VQO19_000175"
     CDS             complement(21600..24152)
                     /locus_tag="VQO19_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HET1348492.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPISYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(24214..25836)
                     /locus_tag="VQO19_000176"
     CDS             complement(24214..25836)
                     /locus_tag="VQO19_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET1348493.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEDDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            26042..27067
                     /gene="trpS"
                     /locus_tag="VQO19_000177"
     CDS             26042..27067
                     /gene="trpS"
                     /locus_tag="VQO19_000177"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HET1348494.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            27219..28697
                     /gene="guaB"
                     /locus_tag="VQO19_000178"
     CDS             27219..28697
                     /gene="guaB"
                     /locus_tag="VQO19_000178"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HET1348495.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(28748..29845)
                     /gene="recF"
                     /locus_tag="VQO19_000179"
     CDS             complement(28748..29845)
                     /gene="recF"
                     /locus_tag="VQO19_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HET1348496.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(29848..30216)
                     /gene="yaaA"
                     /locus_tag="VQO19_000180"
     CDS             complement(29848..30216)
                     /gene="yaaA"
                     /locus_tag="VQO19_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HET1348497.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            30375..31625
                     /locus_tag="VQO19_000181"
     CDS             30375..31625
                     /locus_tag="VQO19_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET1348498.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            31622..32905
                     /locus_tag="VQO19_000182"
     CDS             31622..32905
                     /locus_tag="VQO19_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET1348499.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSIGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKLTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            32947..33768
                     /locus_tag="VQO19_000183"
     CDS             32947..33768
                     /locus_tag="VQO19_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET1348500.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            33779..34324
                     /gene="pgsA"
                     /locus_tag="VQO19_000184"
     CDS             33779..34324
                     /gene="pgsA"
                     /locus_tag="VQO19_000184"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HET1348501.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            34321..35148
                     /locus_tag="VQO19_000185"
     CDS             34321..35148
                     /locus_tag="VQO19_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET1348502.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            35133..35972
                     /locus_tag="VQO19_000186"
     CDS             35133..35972
                     /locus_tag="VQO19_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET1348503.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPNQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            35965..36759
                     /locus_tag="VQO19_000187"
     CDS             35965..36759
                     /locus_tag="VQO19_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET1348504.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            36818..37636
                     /gene="mreC"
                     /locus_tag="VQO19_000188"
     CDS             36818..37636
                     /gene="mreC"
                     /locus_tag="VQO19_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HET1348505.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            37636..38130
                     /gene="mreD"
                     /locus_tag="VQO19_000189"
     CDS             37636..38130
                     /gene="mreD"
                     /locus_tag="VQO19_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HET1348506.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            38224..39402
                     /locus_tag="VQO19_000190"
     CDS             38224..39402
                     /locus_tag="VQO19_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET1348507.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINIVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            39626..40405
                     /gene="rpsB"
                     /locus_tag="VQO19_000191"
     CDS             39626..40405
                     /gene="rpsB"
                     /locus_tag="VQO19_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HET1348508.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            40484..41524
                     /locus_tag="VQO19_000192"
     CDS             40484..41524
                     /locus_tag="VQO19_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HET1348509.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            complement(41645..42571)
                     /gene="cysK"
                     /locus_tag="VQO19_000193"
     CDS             complement(41645..42571)
                     /gene="cysK"
                     /locus_tag="VQO19_000193"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HET1348510.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVYAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDSIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEFEV"
     gene            complement(42856..43491)
                     /locus_tag="VQO19_000194"
     CDS             complement(42856..43491)
                     /locus_tag="VQO19_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HET1348511.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            43547..44845
                     /locus_tag="VQO19_000195"
     CDS             43547..44845
                     /locus_tag="VQO19_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET1348512.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVIEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            44842..45504
                     /locus_tag="VQO19_000196"
     CDS             44842..45504
                     /locus_tag="VQO19_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HET1348513.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            45584..46132
                     /gene="raiA"
                     /locus_tag="VQO19_000197"
     CDS             45584..46132
                     /gene="raiA"
                     /locus_tag="VQO19_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HET1348514.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            46268..48241
                     /locus_tag="VQO19_000198"
     CDS             46268..48241
                     /locus_tag="VQO19_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HET1348515.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNIQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            48238..48690
                     /gene="rplI"
                     /locus_tag="VQO19_000199"
     CDS             48238..48690
                     /gene="rplI"
                     /locus_tag="VQO19_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HET1348516.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            48734..50086
                     /gene="dnaB"
                     /locus_tag="VQO19_000200"
     CDS             48734..50086
                     /gene="dnaB"
                     /locus_tag="VQO19_000200"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HET1348517.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            50088..50354
                     /locus_tag="VQO19_000201"
     CDS             50088..50354
                     /locus_tag="VQO19_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348518.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            50443..51789
                     /gene="cbpD"
                     /locus_tag="VQO19_000202"
     CDS             50443..51789
                     /gene="cbpD"
                     /locus_tag="VQO19_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HET1348519.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGHSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      51872..51974
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            52047..52337
                     /locus_tag="VQO19_000203"
     CDS             52047..52337
                     /locus_tag="VQO19_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HET1348520.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETPH"
     gene            52300..53058
                     /locus_tag="VQO19_000204"
     CDS             52300..53058
                     /locus_tag="VQO19_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET1348521.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            53097..54104
                     /locus_tag="VQO19_000205"
     CDS             53097..54104
                     /locus_tag="VQO19_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET1348522.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            54104..54832
                     /locus_tag="VQO19_000206"
     CDS             54104..54832
                     /locus_tag="VQO19_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1348523.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            54951..55409
                     /locus_tag="VQO19_000207"
     CDS             54951..55409
                     /locus_tag="VQO19_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HET1348524.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            55411..57843
                     /locus_tag="VQO19_000208"
     CDS             55411..57843
                     /locus_tag="VQO19_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET1348525.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVSAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            58164..58817
                     /gene="rr06"
                     /locus_tag="VQO19_000209"
     CDS             58164..58817
                     /gene="rr06"
                     /locus_tag="VQO19_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HET1348526.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            58814..60145
                     /gene="hk06"
                     /locus_tag="VQO19_000210"
     CDS             58814..60145
                     /gene="hk06"
                     /locus_tag="VQO19_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HET1348527.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            60240..60767
                     /locus_tag="VQO19_000211"
     CDS             60240..60767
                     /locus_tag="VQO19_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HET1348528.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     LAHIVFYLSCLVEAMVHKTMFDGMSMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            60846..62996
                     /gene="pspC"
                     /locus_tag="VQO19_000212"
     CDS             60846..62996
                     /gene="pspC"
                     /locus_tag="VQO19_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HET1348529.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLVMGSVVHATENEGST
                     QAATSSNMAKTEHRKAAKQVVDEYIEKMLREIQLDRRKHTQNFAFNMKLSAIKTEYLY
                     GLKEKSEAELPSEVKAKLDAAFEQFKKDTLKLGEKVAEAEKKVAEAEKKAKAQKEEDR
                     RNYPTITYKTLDLEIAESDVEVKKAELELLKEEAKTRNKDTINQAKAKVESKQAEATR
                     LKKIKTDREQAETTRLENIKTDRKKAEEEAKVKAKPKKRTKRGALGEPATPDKKENDA
                     KSSDSSVGEETLPSPSLKPGKKVAEAEKKVEEAEKKAKDQKEEDRRNYPTITYKTLEL
                     DIAESDVEVKKAELELVKEEAKESRDKEKIKQAKAEVESKKAEATRLEKIKTDRKKAE
                     EEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPTEEPENPAPAPKPEKPAEQPKAEKP
                     ADQQAEEDYARRSEEEYNRLTQQQPPKIEKPAPAPQPEQPAQPSTPKTGWKQENGMWY
                     FYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNGS
                     WYYLNANGSMATGWLQYNGSWYYLNANGDMATGWFQYNGSWYYLNANGDMATGWLQYN
                     GSWYYLNNNGAMVTGWLQNNGSWYYLNANGDMATDWVKDGDTWYYLEASGAMKASQWF
                     KVSDKWYYVNGSGALAVNTTVDSYRVNTNGEWVN"
     gene            complement(63226..64206)
                     /gene="dusB"
                     /locus_tag="VQO19_000213"
     CDS             complement(63226..64206)
                     /gene="dusB"
                     /locus_tag="VQO19_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HET1348530.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLID
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(64193..65065)
                     /gene="hslO"
                     /locus_tag="VQO19_000214"
     CDS             complement(64193..65065)
                     /gene="hslO"
                     /locus_tag="VQO19_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HET1348531.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            65230..66657
                     /locus_tag="VQO19_000215"
     CDS             65230..66657
                     /locus_tag="VQO19_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET1348532.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            66816..68324
                     /gene="glpK"
                     /locus_tag="VQO19_000216"
     CDS             66816..68324
                     /gene="glpK"
                     /locus_tag="VQO19_000216"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HET1348533.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            68366..70192
                     /gene="glpO"
                     /locus_tag="VQO19_000217"
     CDS             68366..70192
                     /gene="glpO"
                     /locus_tag="VQO19_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HET1348534.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVKAALAQNDLAELKN"
     gene            70260..70964
                     /locus_tag="VQO19_000218"
     CDS             70260..70964
                     /locus_tag="VQO19_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET1348535.1"
                     /translation="MMSELFGEFLGTLILILLGNGVVAGVVLPKTKSNSAGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEVEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGSRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            71261..71464
                     /locus_tag="VQO19_000219"
     CDS             71261..71464
                     /locus_tag="VQO19_000219"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348536.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEGKKQELLNRLNK"
     gene            complement(71551..72138)
                     /locus_tag="VQO19_000220"
     CDS             complement(71551..72138)
                     /locus_tag="VQO19_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348537.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            73304..74581
                     /gene="ltrA"
                     /locus_tag="VQO19_000221"
     CDS             73304..74581
                     /gene="ltrA"
                     /locus_tag="VQO19_000221"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET1348538.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLRVEITKPNGGIRQLGIPTVMDRMIQQAIVQVISPICEP
                     HFSDTSYGFRPNRSCEKAIMKFLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRHKTLVGTPQGGNLSPLLSNVMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAAAKRVMYSASRFIEKRLGLKVNMTKAKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKLKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     RIVASIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQK
                     SVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            75038..76216
                     /locus_tag="VQO19_000222"
     CDS             75038..76216
                     /locus_tag="VQO19_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET1348539.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            76530..76661
                     /locus_tag="VQO19_000223"
     CDS             76530..76661
                     /locus_tag="VQO19_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HET1348540.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            76682..78232
                     /gene="dltA"
                     /locus_tag="VQO19_000224"
     CDS             76682..78232
                     /gene="dltA"
                     /locus_tag="VQO19_000224"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HET1348541.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMSGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMKNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            78229..79473
                     /gene="dltB"
                     /locus_tag="VQO19_000225"
     CDS             78229..79473
                     /gene="dltB"
                     /locus_tag="VQO19_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HET1348542.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            79487..79726
                     /gene="dltC"
                     /locus_tag="VQO19_000226"
     CDS             79487..79726
                     /gene="dltC"
                     /locus_tag="VQO19_000226"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HET1348543.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            79719..80987
                     /gene="dltD"
                     /locus_tag="VQO19_000227"
     CDS             79719..80987
                     /gene="dltD"
                     /locus_tag="VQO19_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HET1348544.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            81142..81582
                     /gene="adcR"
                     /locus_tag="VQO19_000228"
     CDS             81142..81582
                     /gene="adcR"
                     /locus_tag="VQO19_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HET1348545.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            81582..82286
                     /locus_tag="VQO19_000229"
     CDS             81582..82286
                     /locus_tag="VQO19_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET1348546.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            82279..83085
                     /locus_tag="VQO19_000230"
     CDS             82279..83085
                     /locus_tag="VQO19_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET1348547.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            83095..84600
                     /gene="adcA"
                     /locus_tag="VQO19_000231"
     CDS             83095..84600
                     /gene="adcA"
                     /locus_tag="VQO19_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HET1348548.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISIMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(85727..86500)
                     /locus_tag="VQO19_000232"
     CDS             complement(85727..86500)
                     /locus_tag="VQO19_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET1348549.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPDQKLLDAVELFDGEWVSDIQ"
     gene            86676..88079
                     /locus_tag="VQO19_000233"
     CDS             86676..88079
                     /locus_tag="VQO19_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HET1348550.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDVDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSTLLPEIVSEGNVLGRIKKE
                     YGLSDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            88194..88832
                     /locus_tag="VQO19_000234"
     CDS             88194..88832
                     /locus_tag="VQO19_000234"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HET1348551.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            88844..89284
                     /locus_tag="VQO19_000235"
     CDS             88844..89284
                     /locus_tag="VQO19_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HET1348552.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            89277..89708
                     /locus_tag="VQO19_000236"
     CDS             89277..89708
                     /locus_tag="VQO19_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET1348553.1"
                     /translation="MFNRGILVASHGDFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISNYDSKINLEEIVHNAQNSLFNVKQQLNVEEEEDLCL"
     gene            89699..90169
                     /locus_tag="VQO19_000237"
     CDS             89699..90169
                     /locus_tag="VQO19_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET1348554.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            90194..90967
                     /locus_tag="VQO19_000238"
     CDS             90194..90967
                     /locus_tag="VQO19_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET1348555.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            90964..91764
                     /locus_tag="VQO19_000239"
     CDS             90964..91764
                     /locus_tag="VQO19_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET1348556.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            91823..94117
                     /locus_tag="VQO19_000240"
     CDS             91823..94117
                     /locus_tag="VQO19_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET1348557.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPRTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQDREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            94127..97243
                     /locus_tag="VQO19_000241"
     CDS             94127..97243
                     /locus_tag="VQO19_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET1348558.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            97300..99066
                     /locus_tag="VQO19_000242"
     CDS             97300..99066
                     /locus_tag="VQO19_000242"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HET1348559.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVERVTGYTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            99212..100363
                     /locus_tag="VQO19_000243"
     CDS             99212..100363
                     /locus_tag="VQO19_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HET1348560.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGRPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            100508..101392
                     /locus_tag="VQO19_000244"
     CDS             100508..101392
                     /locus_tag="VQO19_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET1348561.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            101790..102041
                     /locus_tag="VQO19_000245"
     CDS             101790..102041
                     /locus_tag="VQO19_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET1348562.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGDQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            102029..102319
                     /locus_tag="VQO19_000246"
     CDS             102029..102319
                     /locus_tag="VQO19_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348563.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
BASE COUNT        31932 a        17519 c        21104 g        31776 t
ORIGIN      
        1 tttcgtcatt catttttgac tttacttcat cataggatag tgcatgagat tcctcttcta
       61 ctgcttcagg catctttcct gtttcgtaaa gagctttaat ttgtgtacta tccaatgttt
      121 cgtatttcaa taatgcttct gcaattaact tgtgagtttc acgatttgac tgaataattt
      181 cagcagcttt atttcgtgcc tcatttaata atgaacgaac ctcttcatca atttcataag
      241 ctgtttgttc tgaaattgat ttttgaggac tctgtgcacc aagcatagca tggtttcctt
      301 catattgtac tgggccaagt ttttcactca taccgtactc tgtaaccatt gcacgtgcca
      361 tttgtgtcgc ttgttcaaag tcgtttgaag ctcctgtagt ttggacatta aagataattt
      421 cttcagctac acgtccaccc attaagccag ccaattgctc tttcatatct tctttagata
      481 gaagcatttg atcctcttta ggaagtgcaa tcatgtatcc gcctgcacgg ccgcgtggta
      541 caattgtaac cttatggaca acgcgagcat tcgacaagac tagaccaaca atggtatgtc
      601 ctgcctcatg gtaagcaacc aattctcgtt ctttttgtga aactgtctta tctttcttag
      661 aaggtccagc aataactcta tcttctgctt catcaatatc tgaagcatca attatcgatt
      721 tattgcgacg agcagcaact aaagctgctt cattcaagac attctctaaa tcagcaccaa
      781 caaagcctgg agtttgttga gccactaatt tcaaatcaac atcttctgct aaaggcttgt
      841 tcttagcgtg aactttcaag attgcttcac gacctttaac atcaggacgg ccaaccaata
      901 cttttctatc aaaacgtcct ggacgcaaaa gggcaggatc aagtacatct gaacggtttg
      961 tcgcagcgat gacgataatc ccttcatttc cctcaaaacc atccatctca atcaaaagtt
     1021 ggttcaaggt ttgttcacgt tcgtcattac ctccgccgag accgactcca cgttgacgtc
     1081 caacagcatc aatttcatcg ataaagatga tagctggtgc tgcttttttg gcatcctcaa
     1141 aaagagagcg aacacgacta gctccaactc cgacaaacat ttctacaaag tcagaacctg
     1201 agatactaaa gaatggaaca cctgcttctc cagcgactgc cttagcaagc aaagtcttac
     1261 ctgtccccgg aggtccctcc aaaagaacac ctgctggaat acgggctcca agttttgtga
     1321 atcgttttgg atcttttaag aactcaacaa cttcaactag ttcttgtttt tcttcctcag
     1381 ctccagcaac atctgaaaat cttactttaa tatcttcttt atttgctgct ttagccttac
     1441 tacgtccaaa actcattgga ttacggccat tgcctcctcc catatttccc atcatagaga
     1501 ataggaagaa gaatagaatt ccaaatggca caatggatac gagtagatta atccatatac
     1561 cacttgaact ttcatgctta acagttactt ctgctttatg gtcagtagca agtttttgca
     1621 attctgatac ggtagtatct gcaggaagaa tagtgctggt aaatttctct accttagtaa
     1681 cagatggcgt gaaaaactga atacctgttc cttctttact tgttttagga tttttataga
     1741 caccagaaac ttcgataaca ctaccatttg gttggtaagt taattctttt acattaccat
     1801 cggtaatttc ttgtaccaac tcagtatagt tgatttgctg acttcctcct gagttattcc
     1861 cagaatagaa atactggaat cctgtcacaa ggaaaaagat aaataataac catagaaaag
     1921 gatttttaat taaaccatta ttttgttttt tcattaaaga ttattctttc taatttgaat
     1981 acacttcctc tttcaatact ccaatataag gaagattacg ataattttct ttgtagtcta
     2041 aaccataacc tactacaaac tcatttggga tagtaaagca ggtatagtct gcctcaattt
     2101 ctacaacacg tccttctggt ttatccaaca aggttgcaat tttaacagaa gctgcttctc
     2161 ttgctttaaa catatctcgc aaattcttca aagtttgacc tgtatcaatg atatcttcta
     2221 caaatagaac atgtcttcct ttgatatctt gagtcacatc ttgtttaata ttgataacac
     2281 cactacttgc tgttccacca tggtagctag aaaccatcat gaagtccatt tcaatatgtg
     2341 tatcaatatg tttgaccaat tcagccataa aaggaataga tccttttaaa atcccaacta
     2401 agattggatt ttttcctgca taatctttag ttaattgagc acctagtttt ttagctgctt
     2461 ctgtaatttc atcgtgtgaa acgaggactt ttttaatatc gttttctaac attttttacc
     2521 tatctatttt ttctatataa agtacagtgt tcattatatc atttttcgtt tttttactca
     2581 aattattggt cgcaattccc aaaattgaga caatttcacc aaattgctca ataataagag
     2641 cagagtttct cttttccata gggattttca aatcaataaa taaacgtctg agtttttttc
     2701 tatgcccatt ttgaatcaaa acatctcctg tttttcgatg acgaatgtgt atggatgttt
     2761 cacgtgaaac aggtatttgt tgaattgatt caccttctaa tggaagtcca aaggaaaata
     2821 aatatccttg ataagctacc tgattttgat agtgtaacac aagttcatct tccttttcat
     2881 cagcctgcgg actgatttta caaatctgaa actgttggta ctcttttatc aattcatagc
     2941 catttttaat cggatgacga tactggcttt tagattttaa aatctgctga acttcagcaa
     3001 actgagcttt tgtaagattc aaatctggaa aacgattcag ataagtttga agtaaaactc
     3061 tttgtgtaga ctcagagtaa gaaaataact gctgtaaatc ttccacatta atattgttag
     3121 ataattcagc tattgccaaa tcataatcta aaatttcatt gccaatgcct aagattgcat
     3181 ccctaaatcg aggattttct ttttccaatt ctggtaagta agagtttcga atacgatttc
     3241 gaaaataatg attctcctga tttgatgtat cttcaaagtg aaaaattgat ggaaagtctt
     3301 ttttctgaaa atgcaagaag ggacgaatga tttctatctc tccgactact tgcttctcct
     3361 taattcctga tagatagcgc aagcgagttc ctcgaatcaa gcgcatcaaa atcgtttcca
     3421 cctgatcatc agcatggtgg gcagtgacta aagctgtcgc acctgtcttt ttcataacct
     3481 cttgaaaaaa atcataacga aaatttcgtg cacgcgcttc tgaaaattct cctgaaaaat
     3541 tgctgatata aataggaagc tctgcttcag cagccaactt ccttaattcc ttttcttccc
     3601 aatctgattc aattctctgc ttatgattca catgagccag aatcaattca atctctaact
     3661 ctttttgata agtagacaat accttaaata gaaacataga atctaatcca ccagaaagag
     3721 ctagaaccgc cttagcatgc tttttgaaat atcccttctt gagaaaatga tttaaaaaat
     3781 ctggttccct cattttagaa cctcataaac atccttggct atcttagaaa tcgtatcata
     3841 atcagaattc ttagtgaaaa tagaaagaat aaatggagaa tctgcataga caacacccgt
     3901 atcatgctta aattcatccg catctccaat tttatgagct actttaacag aaacaccttt
     3961 ggcaattcgc tgactatcaa aatctgtttt agtcaaagac tctagcacaa atccattttg
     4021 attataaata gcttccataa acttcccggc catcttagaa gaaatcaatt tttcttttgg
     4081 atcccaatca tctcccataa tggcagacat tttggatttg aatgtggcat cagattggtt
     4141 tgaaatgtaa tatcccaata gattatgagc tacattatca gattcttttg atactttcgt
     4201 aattaaatcc tttaaagaat attctttatt atcttctttt ttaggaagac taccacttcc
     4261 ctctggttta taagaacctg gaaaatcatt gactgcagat acgtatttta cagtcgtatc
     4321 taactgataa agaccctcat ttattttttc ttgcgtataa tagagatagg agagtttcaa
     4381 aacgctggct gcatacatct tttcatcttg attgatacca gcttcttttc cagtagtcag
     4441 ttgcttaaca taaatagaga aagaatcttt ctgatatttt tcagataaca tttcttgaac
     4501 tttactcatc cgattatctt cttcagaagt tgattcttta gctacccatc cagcctgatc
     4561 aatatgtaga aattctcttc cttctacaaa catggtcttg tcgattgata cttgcgaata
     4621 agctgataag gatgatttca cttcttttaa atcataagga ctattgtaca gtttaaagtc
     4681 agattctaac catacttttt ttattgttgg agttacctct gattgatcat ataaaaatcg
     4741 tttgtccgca gctataaatt gatgatttga tagcttaaat actggaatcc cttgtttatt
     4801 taagcgccac tcggttattt gaaaacttgt tttgggagtc aattccccag attccactac
     4861 taaatcttca ttcgcataaa caggaacctc tccataaacc atgggagaac ttaatttttc
     4921 tctaaaataa ataccaaagt cagattgtga aaggtaataa atttctttcg aagtatagac
     4981 gacttctttt tctgtgctaa cgacttttga aatggtcaaa aaacttggta gcaacaaaat
     5041 aattaagaat ttacgcattc ttcctttcct tttcttcttg taaacgcaat aattgatttt
     5101 tatcagccaa ttcttccaac ttttcatctg acaaacccaa aaattgctct attacgtcta
     5161 ataaattttc cattttatca cctttgaagc aagtcaggaa tcgtataaac tttttccctc
     5221 gacttagaat aatagtactt cgctcgtgta tatttagcag cataatcttc atctttcaac
     5281 ttggtagcaa atgctgtctc cttatccttt tcatcactca aagtttgata ctgagtttgc
     5341 aagtctgcta attgctgacg tctttggagt aattgctgat aactctgcgc taaattaaaa
     5401 gttggcaaga taaataatag cataatcaaa atcaataccc ctcccataaa acgattccgt
     5461 ttttgtcgtt ctttcatcag gtagcgacga cgttggtatt cattttgaat aaaagaatta
     5521 ttcaattgta caatattttt agacattttc ttctacccgt gtttcactga taatttcata
     5581 cattcctgct gcatcttctt tttttgtact atctttcatc tctagtactt ttacaagcag
     5641 caacttattg ccaaagcgaa tttcaacttg gtcattaact ttcaagtccg ttgaactttt
     5701 ggccaagatt ccattaacct tgattctacc tttatctgct acttcctttg cgactgtacg
     5761 acgcttgata attcgcgata cttttaaata tttatctaat ctcatcctta ttacctcaat
     5821 ttattattgt accattttta tctattttat agaagaaaaa tatcaaatgg aattttcttc
     5881 cttagactct tttatctcta ataaactttc tccaaaaatc agcagacctt ctaaaatttc
     5941 ataatctttc ttattttgaa catcaaatac aagctccatt aattccttat tctcagcgat
     6001 gcctgctttt aagttcgtta cggataaagc tttaaaataa tcttgagcta aaaacagtcg
     6061 ttgagtgact ttttcaaatt gaattgtaat tttattatct tttctttcca cacgttgaac
     6121 aaagaccttg tccaagtatg atttgaccaa accaatctct aaaagatagg ctactacatc
     6181 tgggtattct ccaaaacggt ctatcaactc ctcttgtaac tcttcataat tgacacggtt
     6241 gtcaatttga cgaattttct tgtaaatttc aatcttatgt cgttgatcag aaatataagt
     6301 atcaggaaga taggcatcaa tttgcaaaat caactcagca ttccctttgg ttcttgtgtt
     6361 agcgttagca ttaccgtttc gtttagcaat agcttcctct aataactgcg aatacaattc
     6421 aaaaccaaca gaatcaatga aaccagactg ggattttcct aaaagatttc ctgctccacg
     6481 aatcgaaaga tctcgcattg caatcttaaa gccagagcca aattctgtaa atcctttaat
     6541 cgcttctaat ctcttttcag agacttcact gattgatttt tctggacgat acatgagata
     6601 agcataagca atacgattac tacgaccgac tcttcctctt aactgatata aggttgacaa
     6661 gcccatatgg tccgcatttt caataaataa agtattagca tttggaatgt ccacccctgt
     6721 ctcaataata gtagtcgtca ccaagatatc gtattgtccc tcaataaagt ctaatagagt
     6781 attttccaac tggacttcac tcattcgacc atgaacatat ccaatcgaag cctccggaat
     6841 caactcctgt aattctgaaa ccttctgaac aattgtgtca actttgttgt aaagataata
     6901 aacttgacct ccacgctcca tttcacgcaa gacagcatca cgaatgacac tatcattctt
     6961 ttccaaaaca taggtctgaa caggatagcg attagtcggc ggagtttcaa taacagataa
     7021 atctctgatt cccagcatag acatatggag ggtacgaggg attggcgtag cggtcaaggt
     7081 taggacatcc acttgtttct tcagttcttt caaagtttcc ttatgcttga caccaaatcg
     7141 ctgttcctca tcaataatca tcaagcccaa atcagcaaac acaacatctt ttgacaaaac
     7201 acgatgtgtt ccaatcaaaa tatcgacttg accgtttttc aatttttcaa gtgttgcagt
     7261 ctgctctttt ttacttctaa agcgactcaa cacatcaata ttaactgcaa aattttggaa
     7321 tcgttcctta aaattcgtat agtgctgttg cgctaaaacc gtcgtcggaa ctagaatgac
     7381 aacctgtttg tgatcattga ctgctttaaa ggctgcacgc atagcaactt cagtctttcc
     7441 aaaaccaaca tccccaacta aaagtcgatc cattggctga gaagcctgca tatccctctt
     7501 gatttcctca atactacgaa gttgatcatc cgtttcaaca taagggaaag catcatcaaa
     7561 ggcatcttga tcatcatcat cagctgagaa aacaaaaccc ttcaactgac tacgttcaga
     7621 gtagagtttg attaaatcat cagctatatc ctctacctgg ttcttaacct tttgcttggc
     7681 ctttttaaaa tgaccgtcat ttaatttatt gagttttgga gctttaccat cacttgaaat
     7741 atatttggac agtagatgaa tctgttccac gggaatagaa atttgatcac cattttggta
     7801 ttggacactg acataatcac gatgaattcc cttgatttca atggtttcaa ttcctagata
     7861 ttgaccaatc ccatggatat gatggacaac atagtcccct ttttcaagtt cattgtaatc
     7921 ttttaatctc tctgcatttg aaacatgttg tcttcgaaaa cgacgcttta atttcttttg
     7981 aaaaatctca tgttcagtta tcaataaaat cttttcatct acaaaatgaa aaccatgtct
     8041 gagattaccc tctattaagt ttacagattc tttacagata tttgtcttat ctctagaatc
     8101 caatttaatc tgatattcct ctaacatatc ctccaatgtt ttacttccca ttgaattgct
     8161 agactgcaga ataatggtgt aatccatttt tttatatcgt tcaatttctt cttttagaaa
     8221 agaaaactga ttgaaaaatt cctgcatagg atattgattg aattgataaa ttttgtcaaa
     8281 tttgagattt cctaaaccct tttgaagatt agaaaaaaag gtcactggac tttgtttttt
     8341 atagatttgt tcaatatcag aaaaatactg catatcagaa aatgctttac tattctgtaa
     8401 ttcttctgta aagtactgcg ctaattctct ttcaaagact tcatactgat tcatcaattt
     8461 ttgataatca tcaaagaata ttggagtatc tttttcaata taatcaaaga cagtccatgt
     8521 cttatcatag cacaaagata aaaacttccg agagtctgca tgactttgtt tttggtgaaa
     8581 acttgaaaga atttcttcta ggtatgattt caaaataggt gataaagttt ttgaaatttg
     8641 tttttctaaa gctgactgtc ctcgttgata atccttttct ctcaaaagca tatcactagc
     8701 tggaaagata gtgagttctg tcttattttc tttcgataat tgtgtttcta cttcaaatga
     8761 cctgatacca tcaatttcat caccaaaaaa ctcaattcga caaggttcta actgggatat
     8821 ttcaaaaata tctaaaatat ctcctcgaag actaaattcg ccctgagttt gtacttgagt
     8881 aacttttcga tagccatttt cctttaactg atggataaac gcgtgttgat catattcttc
     8941 accaactgag atttttacaa tactatcttt gaatgcattg ggagacggta aaatcaatcg
     9001 acttgctgcg atattacaaa ctaaaatccc tttcttagat gaatcagtca aaaaacgcaa
     9061 ggcttcaacc cgtgaaataa ttttttcctg tgaagacatc aaaaactcca ccataggagc
     9121 atcatctacc aaaaatggat agacgagttc ctcacccaag atagatataa gatcactaac
     9181 aagtccttct gcttctccat aagttgacat caataacaca atcctatctt ctttttctaa
     9241 actgcttgca attgcaagag ccttagtaga tgttgataaa ccaagtatta gttgtctttt
     9301 cttatctgtt aaattttgat gccatttttt aatctgatca ttttctgaga ataaatctaa
     9361 taaggtcacc atttatccgt tatacctctg cattgttttc tcaaaatttt tctcttgtaa
     9421 atagtagttt acagaatcgt caactttgtc aacagactgt aaaataccga tatactcatc
     9481 cctgtcaaac ttactcaaaa catgatgaac aactgacata ccatttttag gtcttccaat
     9541 tccaatctta acacggttaa agacctgagt tcctatatgt tgaataatag acttgatacc
     9601 attatgacca cctgctgagc cttttgctct taaacgaatt ttcccaactt ccatgtcaag
     9661 atcatcgtaa atgataagta aatcgtcaat atccaaacca tagtaagtta ataaagcatg
     9721 aactgctttt ccactttcat tcataaaggt cgttggttta accagataaa ttttttctcc
     9781 atttaggaaa aaggatgcta ggtcagcttg aaatatctta tcgtgtgtaa aagtgacatt
     9841 ctgtttcttc gctagttgat caatcaacat aaaaccaaca ttgtgttttg tttcaaaata
     9901 tttatcccct ggatttccca agcctacaag taatttggtc atttattttt cctttcaaaa
     9961 gccaaaaggg ttggaatttt tttccaacct aattgacacc atttattaat ttttagacat
    10021 taaagcggaa ttccatgata tcgccatctt gaacgatata ttcttttcct tcttcacgca
    10081 agcgtccagc ttcttttacg gccttttcag atccgtattt cactagatct tcatatgaca
    10141 tggttactgc acgaataaag cctttttcaa agtctgagtg gataatacca gctgcttgag
    10201 gagccttcat accacgtttg aaagtccaag cgcgaacttc tttttcacca gctgtaaagt
    10261 aagttcccaa tccaagcaag tggtaagctg cacgcgtcaa cttatctaca cctgattctg
    10321 tcaaaccaat ggcttcaaga aactcttttt tatcttcatc atccaattca gaaatttctt
    10381 cctcagcacg cgcagaaata acgactactt cagcattttc tgtcgctgca aattcacgaa
    10441 tttgtttgac atagtcgata gagtcaggtt ctgaaaccac atcctcgtcc acattagcta
    10501 cataaagaac tggtttagtc gtcaaaagga aaagaccttt gacaaccttt tgttcctcat
    10561 ctgtaaattc aatggtacga gctgatttcc cgtcttctag gactggttta atcttttgaa
    10621 gaacattaaa ttctgctact gattctttat ctttttgcgt acgtgccatc ttttctacac
    10681 gcgcatatcg tttgttcact gattctaagt cagcaagaat taattccaga ttaattgtat
    10741 caatatctgc aagtggatct acaaaggcgt cttcacgtcc ttgctcgcgc atcacatttt
    10801 catcatcaaa agcacgaact acgtgaacaa tcgcatctac ttcacgaata ttggccaaga
    10861 atttattccc tagcccttct ccttttgaag ctccttttac aatccctgca atatccgtaa
    10921 attcaaatgt tgtgggaact gtctttttag gagttatcat ttcagttagt ttttgtaggc
    10981 gttcatctgg aacttccacc attccaacat ttggatcaat agtcgcaaat gggtagtttg
    11041 ctgcctctgc tcctgctttt gtaattgcat taaatagtgt tgatttacca acgtttggca
    11101 aaccaacgat acctgctgtc aaagccatat ttctcattct ccgttttcat ttcaatccct
    11161 aatattataa cacaaaaagg gataaagtgc taaccctcta actaagggtt ctcagtcaat
    11221 aattttattc atttttcgct caaaatcata tcgccccatc atgacaacat gctcacaatt
    11281 actgcatttt attttgatat ctgctcctac acgtgtaatt tcccaacgat tagccttttt
    11341 accagtcgac ttgattgtac aagcgtgtga ttttttcatc tcaacaaaat ttccaacttg
    11401 atacatacta ctctcctttt ctttttcgat tatatcataa aagaggcgag ccaggctcaa
    11461 cctctttcac ttaatttgta cgaactggtg taatgagctg catgaagtct tcgtcagtat
    11521 ctgctggcac aagagtaaat ggacgaacag ctgagataaa gctaatggtc accttttcgc
    11581 tatttaaagc tttaagagaa tcaatcaagt aagttgggtt gaaactaatg gtcaaatctt
    11641 caccagtaac ctgatcagta tcgatttctt cgtttacttt accaacttct ggagagtgaa
    11701 catgggcgct aacaacccca tccttaattt caagtttcac agtaccattt tgagtcgcac
    11761 ttgataaaag acgggcacgc tccattgact ggcgtaagtt taccacatta aaagtaatag
    11821 tagtgttaaa gtctgttgga atcaagcgat ctgtatcagg atagtttcct tctaggagac
    11881 gagtatagaa gctaatattt tcgcttctaa agaggatttg gttattggca aagaaaatct
    11941 ctacagtttc gatatcatct gtaaataccg ctgaaaattc gcgtagagaa cggctaggaa
    12001 ttacgacatc aaaatcatca ctattttttt caagagtcaa ttttttctgg cttaggcgat
    12061 gagagtctgt tgcaactgtt tttaactctt tgtgttgact caatacgaag tggacacctg
    12121 ttaaaatcgg acgactctct tgtgtacttg cagcaaaggc tgtttcatta ataattttct
    12181 tgagtaattt tgtttcaagt attaaaggag tgcttgctga aatttcttgg attcgtggat
    12241 attgttcgct atcttttcct tttagggtaa tttctgattt gccactggtt aaaacaattt
    12301 gattttgttc aatttcttta aaatcaagag ttacatcagg taaactagat actacattga
    12361 taaagaaaga agcttcaaga aggatcgaac ctaaagaagt aattaacaaa ccagcatctt
    12421 catttttttg agaaataaaa ttttcaattg aaatttgacc atttgaacca attaaagtaa
    12481 taccttcatt ggtcacgtca atttttactg ttgataaaat aggaatggca tttttagaac
    12541 taatagctct cttagtagta tttaatgctt gtagaaataa atttttatta attgaaaaat
    12601 gaatcatgga ttctccttta tttattttta gtattagaaa gataatagta ataatagagt
    12661 ctgtgaaatc tgtggaaaac agcctttaaa caagtcatat caagtttttt agcttgttta
    12721 aaaaatgtgg ataaaaaaga taaaaaacta aaagttatcc acaaattatt tgattttctt
    12781 tttgattgat tcaatttcta aacgtaaatt atcgtcttga tcaatcaaag attttatttt
    12841 ggcatgggca tgaatgactg tggtatgatc ttttccccca aattccttcc caatttttgg
    12901 aagactatta tctgttagtt ctctagataa atacatggct acttgacggg ccaaaacaat
    12961 attttgaagg cgtctacttc ccttcatttc tttgatacta acaccataaa agttaccaac
    13021 ttcagtttgg attttatcaa ttgggatgac gagcatttgg ctaacatctt gtttgcgggc
    13081 tctaatggct tctgcagcaa tatcaatagt gatatccttg atttttttta ctctggcaat
    13141 taaagtgatg tcgttgatgg ctccctcaag atctcgaaca tttgaatcaa attgcccagc
    13201 taggtattct agagtatcac tttggaaatt gtagcctaaa tgttccgtct tactttgtaa
    13261 aatggcaata cgtgtttcaa agtcaggggg tgtgatagtt tgtgtcaatc cccaactaaa
    13321 acgcgtgaca agcctctcct cgagcccttc tagatgtttt ggactacgat cactcgttag
    13381 gacaatctgt ttttgcttgt catgaagggc gttaaaggta ttgaaaaatt cttcctgagt
    13441 tgcgactttt tttccgctga gtgactgtat atcatcgatt aacaaaagat caagactacg
    13501 ataggtcttt ttaaactttt ccatttcccc aagtcttagg tgatcaagaa agtcattaat
    13561 aaagctttcg gcagggatat atttaacacg cgcattagga atatttttta gaatttcatt
    13621 tccaatagcg tttaataagt gagtcttacc aaggcctggt cctccataga taaaaagagg
    13681 gttataggtc agagccaaat cttcagagac agctaaagcg gctgatacag cccaaacatt
    13741 tccatcccct tgaataaaat tatcaaaggt atacttttct tttaatcccg tatctgaata
    13801 aggaatagat actaactttg gactatagtc ataaagagtt aaatttgtag cttcttcaac
    13861 ttgtgagcta gtcgtatctt gaggtttggt gaaaatatag tggggagtta tttcagcgtc
    13921 ataaatttca aaaccagcta ctacaataat atcttttagt tgtttttccc agaccatttc
    13981 catttcagag cgaggtagaa atatagtggc aacattttcc tctaccttga tgagttcagc
    14041 ttgaatagca tagaaatcat acatggatcg agtcagtctt tcttgtgcaa attctaatat
    14101 acgattccaa aattgttttt ctttcaatcc tttctcctcc tttactattt aaaagtttaa
    14161 tactagagat attttaccat agatagcaag aattttccac aagctgtgaa aaataatcca
    14221 caatgttacc aaactttatc cacaggttgg ggataaaaga agaaattatt gatttattaa
    14281 gctttttatc gaaaaacata gtggataacc ttgtgagata aaaaaataaa agaacagcct
    14341 tatttcaggc tgttgataat tctactatat tcttcttgat ttgaaaaaga aataatgatt
    14401 tttccactgt cttttttaga tagtttaatt tctacatcta aaccgagtag ttttcttaac
    14461 tgtttttctt cattttgtat gaaatgatta gttttttgct gtttcttttg ttttttctct
    14521 gtcagaagag tttctaactt ccttacagaa atatcttctt ctataatccg ttgaaagaaa
    14581 tagtcttgtt gttccttatt taacccaact agggaacgcg catgggcttg tgatagtttg
    14641 ccattttcta cttctgagag aatctgttct ggcaaggaaa gtaaacgaat ggagttgctg
    14701 atatatggac gagacttgcc catcttatct gcaatttcag catgggtgaa tcctttctct
    14761 acgagagatt cataggcgcg tgcttcttct attgggttta aattttctct ctgtaaattt
    14821 tcaataatgg actggaccat catctcttgg tctgaaatct gtttaacaac agctgggata
    14881 gaccgtagac cagctaaaag tgaagcccga tagcgtctct ctcctgcaag gatttcataa
    14941 ccaataacag gagattgacg aacaataatc ggttgaatga ccccattttc tttgatagac
    15001 tgtgctagtt catctagttt ttctctatca aattcttttc ggggttgata gggatttttt
    15061 tgtatatctg tgatagaaat catttcaaat ttttccatga ttctacacta acacatcttt
    15121 tctcttatgt aaagctttct ttacatagat gtcaatcaag attctaaatc acctgaactc
    15181 ttgttaagtt tgatagaggt agtttcttct ttcccgttac gatagtaggt tatcttaatg
    15241 gtgtctccga tagaatggtt gtaaagagca ctttgtaagt ctgttgatga agcaatctct
    15301 ttgtcatcta cttttgtaat tacatcgtat ttttcaaggt gaccattggc aggcatatta
    15361 ctttgtaccg aacgaacaac tacaccagat gtaacattac ttggaatatt gagtcttctg
    15421 atgtcgcttg tactcacatt agataaatta accatctgga ttcccaaagc tggacgcgtc
    15481 acttttccgt ttttttctaa ctgttcaata atattgatag catcatttgc aggaattgcg
    15541 aaaccaagac cttctacaga tgttcctcca tttgtagcaa ttttacttga ggtaattccg
    15601 ataacctgcc cttgaatatt gatcagtggg ccgccagagt tacctgggtt aatagcagta
    15661 tcagtttgga tggcttttgt agaaatagct tgtccatctt ccgatcttaa ggatacattt
    15721 ctattgagac tggatacgat accttgagtg acagtatttg catattcaga acctaacggg
    15781 ctaccgatgg caatagcagt ttctcctaca gttaacttac tagaatcacc aaactcagct
    15841 actgttgtca ctttttctga agagattttg acgacagcaa tatcagagaa agtgtcagct
    15901 ccgacaattt ctccaggtac tttagtccca tctgacaatc taatatctac tttgctggcg
    15961 ccatttataa cgtgattgtt ggtgacgatg taagcttctt tatcattctt tttataaata
    16021 actccagatc cttcactaga gattcgctga gaatctgtgt cagtatcatc attgccaaat
    16081 acgctatttt gtctgtttgc cgaataagta ataacagaaa caacagcatc ttttactttg
    16141 ttaacagcct gtgttgttga attttcgttc ttataggcag tttgtgtaat agtactattg
    16201 ttgttagagt tgtttacact acttttttga gttagttgag ttattgaaaa actacccaag
    16261 gctccactaa aaaagctaat gacgataacg actaataatt gaaaccattt tttgtaaaat
    16321 gtttttagat gtttcatatt tgcctccata tgtttgaatt actgaaagta taaactgact
    16381 agcttaatta taacttaaac acaaaagttt tacacaaact gtggataact cttttgaaac
    16441 tgtgattttc ttaattgaaa tctatttttt attttgtgaa taagatgtga aaaaatagag
    16501 aatatgttag aatagagtca tgaaaattaa agttgtaaca gttgggaaac tgaaagaaaa
    16561 gtatttaaaa gatggtatcg cagagtattc aaaacgaatt tctagatttg ctaagtttga
    16621 aatgattgag ttatcagatg aaaaaacacc agataaggcc agtgaatcag aaaatcaaaa
    16681 gattttagaa atagaaggtc agagaatttt atcaaaaatt gctgaccgtg atttcgttat
    16741 tgtgttagcc attgaaggga aaactttctt ctcagaagaa tttagtaagc agttagaaga
    16801 aacttctata aaaggatttt ctactcttac ttttattatt gggggaagtt taggattgtc
    16861 atcatctgta aaaaatagag ccaatctttc tgtcagtttt ggtcgcctaa ccttacccca
    16921 tcagttaatg agactagttc ttgttgaaca aatctatcgc gcttttacga ttcagcaggg
    16981 attcccctac cataaataga aaattgactt ttaattgaat ttttggtaga ataattgtat
    17041 taggtctcat agctcagctg gatagagcat tcgccttcta agcgaacggt cgcaggttcg
    17101 aatcctgctg ggatcaatat aatagcaaag ctgggaattt tcccggcttt tttcttaaaa
    17161 aagtacactt tgggagaaaa aaatgacagt tgagagaatt ttatctaaaa cgaaattcca
    17221 ttttgtataa tgttttttgt aagttagctt acaagaaaaa acattttagg agattttatt
    17281 atgaaaaaca cagttaaatt ggaacagttt gtagctttga aggaaaaaga cttacaaaag
    17341 attaaaggtg gggagatgag gttgtcaaaa ttcttccgtg attttatttt acaaagaaaa
    17401 aagtaatgaa ataaggggaa agagtaatgg atttatttgg atttgggacg gttattgttc
    17461 attttttaat tattagtcac agttaccatt ttatttgtaa aggtcaaata aatagaaaag
    17521 aattattcgt ttttggtgct tatacattac taacagaaat agtatttgat tttcccttat
    17581 atattctata tttagatggg ttagggattg aaagattttt atttcctttg ggattatatt
    17641 cctattttcg atggatgaaa cagtatgaga gggatagagg actattccta agtttactac
    17701 tatctctttt atatgagagc actcataact ttctgtccgt aactttctcc tctataacag
    17761 gagataattt tgttttacaa tatcatttcc cattcttttt cgttgtgacg gtgttaacct
    17821 attttgttac attaaaaatc atttactatt tccatttgga actagcctat tttgacgagg
    17881 actaccttta tcctttcttg aaaaaagtat tttttgcttt actattgcta catattgtat
    17941 ctttcgtttc agatatggta agtacgatta aacatttgaa tagttttgga agtattttgt
    18001 catctattgt ctttatctct ctccttttga ccttctttgc aatgaattct cataaagttc
    18061 aaatggagaa agagattgct ttgaagcaga agaaatttga acagaaacat ttacagaatt
    18121 acacagatga aattgttggt ctgtataatg aaatccgtgg ttttcgacat gattatgctg
    18181 gaatgcttgt cagcatgcag atggcaattg acagtggtaa tttacaggaa attgacagaa
    18241 tttacaatga agttttagtc aaagcaaatc ataaattgcg ttcagataag tacacttact
    18301 ttgatttgaa caacatagaa gactcagctt tacgaagttt ggttgctcag tcaattgtct
    18361 atgctcgaaa taatggtgta gagtttacac tggaagtaaa agatacgatt accaagcttc
    18421 caattgaact attggatttg gttcgtatca tgagcgtttt attgaataat gctgtcgaag
    18481 gatcggctga tagctataaa aagcagatgg aagtagcagt tattaagatg gaaactgaaa
    18541 cagttattgt gattcagaat tcatgtaaaa tgacgatgac tccttcagga gatctatttg
    18601 ccttaggatt ctccactaag ggaagaaatc gcggagtcgg attaaataat gtgaaagaac
    18661 tactagataa gtacaacaat attattttag aaacagagat ggaaggcagt acatttagac
    18721 aaatcattag atttaagagg gaatttgaat gaaagtttta attttagaag atgttattga
    18781 acatcaagtg agactagaga gaatattgga tgaaatttcg aaagaatcga atattccaat
    18841 atcatacaag acaacgggaa aagtccgtga atttgaagaa tacattgaaa atgatgaagt
    18901 aaatcagctt tatttcctag atatcgatat tcatggaatt gagaaaaagg gatttgaagt
    18961 ggctcagctc attcgtcatt acaatcctta cgctattatc gtctttatca ctagtcgatc
    19021 agagtttgcg actctaacct ataaatatca ggtatcagcc ctagattttg ttgataagga
    19081 tatcaatgat gagatgttta agaagagaat tgagcaaaat atcttctaca cgaagagtat
    19141 gttacttgaa aatgaagatg ttgtagatta tttcgactac aattacaagg gaaatgattt
    19201 aaaaattcct taccatgata ttttgtatat tgaaacaaca ggggtatctc ataaattgcg
    19261 cattattggt aagaattttg caaaagagtt ttatggtacc atgacagata ttcaggaaaa
    19321 ggacaaacat actcagcgat tttattctcc tcacaagtca tttttggtaa atataggcaa
    19381 tatcagagaa attgatcgaa aaaacttaga aattgttttc tatgaagacc atcgttgtcc
    19441 tatttcaaga ttaaaaatta gaaaattaaa agatatttta gagaaaaaat ctcaaaagtg
    19501 attgacaatt agcaagaaat tgatataatg gttatatctg ctacagatag aaggtccgtt
    19561 ggtcaagggg ttaagacacc gccttttcac ggcggtaaca cgggttcgaa tcccgtacgg
    19621 actattttat ccgccatagc tcagttggta gtagcgcatg actgttaatc atgatgtcgt
    19681 aggttcgagt cctactggcg gagtatagat aaaagggaac acagctgtgt tcctcttttt
    19741 gtatcaattt gtatcaccaa gcattttcat aaggaagtct gttatttctt gagaactttc
    19801 tttttttcca tgtgcaatcc aagtttggca gacaccaaaa agtgcatgag ttagatagat
    19861 gctactatat tctaattcgg tggtatttag attcagttgc ataaatcgct tttgtaaatc
    19921 tgtactaagc atgatatgaa gtttatttcg taagaaattt tggatttctt tagtcccatt
    19981 ttcagaaaga agggcagcca gaagtggttc tgactctaga tattcaaaaa cttctaaaat
    20041 agcgtctctt ttgtgatgag catgtttttg aaaaatatat tcaaatgtat ggaatagctt
    20101 gctttgatag tgctcaatca tatcatactt atccttatag tgagtataga agctggaacg
    20161 actaattccg gctttttcta ctaatttgac agtagaaatt ttatcaaatg gctgttccat
    20221 cagtaattgt accatagcat tttcaatagt tcgctttgtt tttaagcgtt tgttactttc
    20281 ttgcatattt cctccttgta aacaaattag actatatgtc taaaaataga ttttttatct
    20341 tgtaatttag attttttaat gtataatcta ttatatcaaa attttagaca atatgtttaa
    20401 aaaaggagaa actaagttta aagaatggaa agcaatttta aaaaaaacca acctttatta
    20461 ttgtcatgat cgggatttct cttattccag atctgtacaa tatcatattt ttgtcatcaa
    20521 tgtgggatcc atatgggcaa ttgtctgact tacctgtggc agttgtaaat aatgataaag
    20581 aggcttccta taatggtaat actatggcaa taggaaaaga catggtgtcc aatttaaaag
    20641 aaaataaaac cttggatttt cattttgtag atgaagagga aggaaagaag ggattggaag
    20701 atggcgatta ctatatggta gtgactttac caagtgattt atctgaaaaa acaactacat
    20761 tatccaatat tcaatcgaca gcagcttatc aatcattgac aagtgagcaa caaactgaga
    20821 taagtgattc tgtatctcaa aatttaactg ctagtattca atcggctcag tcaattgtag
    20881 ctttagtaca agatttacag ggaagtttag aaaacttaca aaatcaatct tctaatcttt
    20941 cgactttaaa aaatcaatct aatcaagtat cacctattac ttctacttct ttgataggat
    21001 tgtcaagtgg attaacagag atacaaggag atgttactag caaattagtt cctgccagtc
    21061 agtcgattgc atcaggtgta aacgcatata ctacaggtgt tgataaagtt tctcaggacg
    21121 tcatccagag agccgttggg cttggttgaa atctcgagct gaaataaatg gtattatagc
    21181 tgttttggca ggaattttgg tatatggagg agttcatctt attggtttaa ctgctaatca
    21241 tgagatgaga atatttattc tcatcatcct aacaagttta gtattcatgt ctatggtgac
    21301 cactttaaca acgtggaata gccgtatagg agctttcttc tcacttattt tgcttttact
    21361 acagttagca tcaagtgcag gtacttatcc acttgctttg acaaatgatt tctttagatc
    21421 tattaatccc tggttaccaa tgagctattc agtttcggga ttacgacaaa caatctccat
    21481 caacaagtca ttttcctagc tgtcatacta gctctattta ctggtttagg tatgctagcc
    21541 tatcaacata agaaaatgga agaagattaa aaaaatcgac cgattaactg gtcgattttt
    21601 tatgccttag atgactttcg tctgtgatta tagattccaa atagtaagag agaagtaaag
    21661 gaacagattg ctccagtaat aaaaccattg ggaatgaagg aaagtgtaat agttcctttc
    21721 cccttgggaa tgtcaacttt cataaatcca gtttgagctt gtttaatttc tattttctta
    21781 ccatcttggt aggcagacca acctttgtca taaggaatgg tgaagaaaat agatgtatct
    21841 tgttggacat catatgtagc aaaaaccttg tttttagaag ttgatactgt gacaggttgt
    21901 tctttaattt tttgaattgc ctcggtgaaa gttttggtat ctaaacgata gaaggtagga
    21961 gattcaaatg atacttgtga atttccaggg aaactaacat tgatattgaa agtttttttc
    22021 tctttagtat atcctagatt aaagaaggag aagacattat cagttgtaaa agtctttttt
    22081 tcaccattta caaggatgtc aaccttcttt tgtttatcgt tagaaaagtg aaggtttatg
    22141 aaagagagat aaacttggct gttttctgga acttcaattt gatactggat tgctgcatct
    22201 tcatttgaag aacttgtgac actaatcaaa tcattagtat tttctatttt ttctgttttt
    22261 tcataagata ttggagaaaa ataatcaaaa ttgacgttag caagttgatt taaaaatgag
    22321 gcctgattat ccaaggtatg ttcattgaac ttgacatcat tgtaaacaga ttgactagca
    22381 actgcaatcg gaagagagta ttgattttca tatagggtaa gattatcttt ttgatagata
    22441 tctttaaaac catacttatc aataggactg tctgagatat tgtactggat accaaataaa
    22501 ctatcagcca aaatactatt atttgcatat cggagattga gattagtccc agaggattta
    22561 aaaccaagtt tatctaaagt agagcttgat gaacgatttc gaacagatga aaattgagag
    22621 attccattgt agttgaattt catactgtca tttcctgtct gagtttgtag tttttcagta
    22681 cgagtaaatt gatttccaat atatgttgag aaagattcca tagctgggat atctcgacta
    22741 taagcacttc gagaagcaaa tccccattcc ttagcaattc cgtccatttg agatgaagca
    22801 tttaaactca tttcaaccag tataaataaa gagattagaa tggcaaatag attcacagat
    22861 ataaactttt tgataactgc aaggagtaaa agagaataga caaccaaaaa ttcaagagta
    22921 agcagaatat tcaaatctgt taaaaaagaa taatgcgatt ttagatagat ggtagctaaa
    22981 aatcctgcta ctacaagaaa aagcgaaact aaaaaattcc agactttaag ttctttcaga
    23041 cgctttaaga cttctgctgc tgtgtaaatt aacaaggtag agaaaatcca agcatagcga
    23101 tgtaaaaaca tgtttggagt atgcatgcct tgccaaaata agtcaagagc ttctatgtaa
    23161 aagcttgcaa ttagaaatgc aaagaatatt acatatatga gtttcacgtg aaacttaata
    23221 gatttcagcg taaaaaataa aatggtcaaa ataaagggaa gtagtccaac aaaaatcatt
    23281 gggatggccc catactttgt tgtgtcaaag gaaccaatga attgcttagc aaagagatca
    23341 agataccagc tactttcagt ttgaaacttt gtaacttcag tcaatttttc cccatgtgtc
    23401 tgtaaatcaa atagagtggg aagagtcata atcaaactag ccataccagc taaaaaggag
    23461 ataactatga aatcaagaac agatgatttt cgagtcttaa agtcccacga aatttgacag
    23521 agataccaga aaataagaaa caatactgtc atatatccaa aataataatt ttgaataaat
    23581 aagattgaca gacttgtaaa gtacaatagg agtttctttt cagttatcag tagatgtaaa
    23641 ccagttataa ttaaaggaat caagataaaa acatctagcc aggtttttat ctctaattga
    23701 ctgacagtga aactcatcag agcataggaa gtagataagg ctagttttaa agtctgaggg
    23761 atagattgaa acaatttatt caaactaaaa aaggttgaca gaccaatcaa tccaaatttt
    23821 aagagagtgg tcagatagac agcatctggc atattcgtta gatcaaaaaa gtaaactaga
    23881 ggcgcgagaa aactacccaa gtaataacta gatagggcat agaagtttag ccctagacca
    23941 cttgtaaagg tgtaaaacag actactattt ccatgtagga tatttcgtaa ggctacatca
    24001 aaaataacgt attgatgaaa gccatctcct aatagaggag agttgtcgct attccagtag
    24061 ataccttgag atagatatac tccagacata atcactacag gaatgatgaa agaaataaaa
    24121 taggttcgat atgtttttaa aaatgatttc atgttacctc gtagaatgat agaaaactca
    24181 gttggttaac ccaactgagt tttgaagttt tatttagtct ttccaaagtt ctttaacttt
    24241 tgcttgtact tctgcatttt ctaggaattc atcgtaggtt tcatcgatac ggtcaatgac
    24301 gccattttta gataagacaa tgatatggtt agccaaagtt tgaataaact cgtggtcatg
    24361 gctggcaaag atgattgatt ctttaaagtt tttcaatcca tcattcaagc ttgagataga
    24421 ttccaagtcc aagtgatttg ttggatcatc aagtacaagg acatttgatt ttaagagcat
    24481 gagttttgaa agcatgacac gaactttttc tccccctgac aagacattta caggtttgtt
    24541 aacttcatct ccagagaaga gcatacggcc gaggaaacca cgtaggaaag tattgtcatc
    24601 atcttcttta cttgcgaatt gacgcaacca gtcaagaatt gattctcctc ctgcaaaatc
    24661 agctgagtta tcttttggta ggtaagattg actagttgta actccccact tgacagttcc
    24721 ttcatagtca atatctccca tgattgcacg aattaatgca gtcgtttgaa tatcattttg
    24781 tccaataagt gctgtcttat catctggacg caagatgaaa ctaatattat ccaagatagt
    24841 ttcaccatca atctttacag ttagattttc tactgtcaag agatcattac caatctcacg
    24901 ttccgcttta aagttgataa atggatattt acgactagat ggtacaatct cttctagctc
    24961 aatcttatca agcattttct tacgtgatgt tgcctgcctt gacttagaag cattggcaga
    25021 gaaacgagca acgaattctt gcaattgttt aattttttct tctgctttag cattacggtc
    25081 tgctagcaat ttagcagcaa gctcagaaga ttccttccag aagtcgtagt ttccgacata
    25141 gagtttgatt tttccaaagt caaggtcggc catgtgagta caaactttgt ttaagaagtg
    25201 acggtcgtgg gatactacga taactgtgtt atcaaagtca atcaagaagt cttctaacca
    25261 agtaatcgat tggatatcca aaccgttagt aggctcgtcc aagagaagaa catctggttt
    25321 accaaaaagt gctttggcga ggagaacctt tactttttca ccgttggcca attcgctcat
    25381 gttttggtag tgtaattctt ctggaatgtt taggttttga agtagttgag aggcttcact
    25441 ctctgcttcc caacctccaa gttcggcaaa ctctccttcg agttcggcag cacgaacccc
    25501 gtcctcgtct gagaaatctt ccttcatgta gatagcatct ttctctttca tgatgctata
    25561 aagtttttca tttcccatga taacgacatc aatggcacgt tcatcttcgt agtcaaagtg
    25621 attttgacga agaacagaga gacgttcatc tggaccaaga gagatgtgac cagtagtagg
    25681 ttcgatatct ccagctaaaa tttttaaaaa ggttgatttt ccggcaccat tagcaccgat
    25741 taatccgtaa gtatttcctt ctgtaaattt gatattgaca tcatcaaaaa gtttgcgatc
    25801 actaaaacgt agtgaaacat cagatactgt aagcaatgtt tttctcctat atgtgtaata
    25861 tatttattct actagaaaat acagaaatat tcaaattttt atttgtcaat tttgtgtaaa
    25921 ttatatttac agtatccttt acacaaatct gtaaaaagca aggctgattt attttgataa
    25981 attacggtta tttcattaaa aaaatgctat aattgaaagg actatatcga aggagaacaa
    26041 aatgactaaa cccattattt taacaggaga ccgtccaaca ggaaaattgc atattggaca
    26101 ttatgttgga agtctcaaaa atcgagtatt attacaggaa gaggataagt atgatatgtt
    26161 tgtgttcttg gctgaccaac aagccttgac agatcatgcc aaagatcctc aaaccattgt
    26221 agagtctatc ggaaatgtgg ctttggatta tcttgcagtt ggattggatc caaataagtc
    26281 aactattttt attcaaagcc agattccaga gttggctgag ttgtctatgt attatatgaa
    26341 tctagtttcg ttagcacgtt tggagcgaaa tccaacagtc aagacagaga tttctcagaa
    26401 aggatttgga gaaagcattc cgacaggatt cttggtctat ccaatcgctc aagcagctga
    26461 tatcacagct ttcaaggcta attatgttcc tgttgggaca gatcagaaac caatgattga
    26521 gcaaactcgt gaaattgttc gttcttttaa caatgcatat aactgtgatg tcttggtaga
    26581 gccggaaggt atttatccag aaaatgagag agcagggcgt ttgcctggtt tagatggaaa
    26641 tgctaaaatg tctaaatcac taaataatgg tatttattta gctgatgatg cggatacttt
    26701 gcgtaaaaaa gtaatgagta tgtatacaga tccagatcat atccgcgttg aggatccagg
    26761 taagattgag ggaaatatgg ttttccatta tctagatgtt tttggtcgtc cagaagatgc
    26821 tcaagaaatt gctgatatga aagaacgtta tcaacgaggt ggtcttggtg atgtgaagac
    26881 caagcgttat ctacttgaaa tattagaacg tgaactgggt cctattcgtg agcgccgtat
    26941 tgaatttgct aaggatatgg gagaagttta taatatgatt caaaaaggta gtgaaagagc
    27001 gcgtgaagtt gcgggtcaaa ccctatctga ggtaaaaggg gcaatgggac ttcattactt
    27061 taactaagtt tattttacaa gaaactatca tttctatctc gaagaaaaga tagtttttta
    27121 tttacccctg taacatttga caaattttta tagaatggta tgatagatac aatataaaaa
    27181 gagtcaagct caaaaagaaa gaaaagagga aacttcgaat gtctaattgg gacactaaat
    27241 ttttgaaaaa aggttttacc tttgatgatg tattgcttat tccagctgaa agtcatgtgt
    27301 tgcctaacga tgcagattta acaactaaat tggcagataa tttgacttta aatatcccaa
    27361 ttattaccgc tgccatggac acagttacag agagtcaaat ggccattgct attgctcgtg
    27421 caggtggtct cggagttatc cataaaaaca tgtcaattgc tcaacaagca gacgaggttc
    27481 gtaaggtaaa acgttctgaa aatggagtta ttattgatcc gttcttcttg acgcctgaac
    27541 atacaattgc tgaagcagat gagcttatgg gtcgttaccg catcagtggt gttccagttg
    27601 ttgaaacact tgaaaatcgt aaattggttg gtattttgac aaaccgagat cttcgtttta
    27661 tttcagatta taatcaacca atttcaaacc atatgactag tgaaaatctt gttactgctc
    27721 ctgtgggtac ggatcttgca acggctgaga gtattcttca agagcatcgt attgaaaaac
    27781 ttccgttggt cgatgaagaa ggcagtcttt ctggtttgat cactatcaaa gatattgaaa
    27841 aagttattga gtttccaaat gcggctaaag atgagtttgg tcgtcttcta gttgcaggtg
    27901 cagtaggtgt tacttcagat acatttgaac gtgcagaggc tctttttgag gcaggagcgg
    27961 atgcgattgt tattgatact gcacatggtc attctgcagg tgtcttgcgt aaaattgccg
    28021 agattcgtgc tcatttccca gatcggactt tgattgctgg aaatattgct actgctgaag
    28081 gtgcacgtgc cctttatgaa gcgggtgtag acgttgttaa ggttggtatt ggaccaggtt
    28141 ctatctgtac tactcgtgtg attgctggtg ttggtgttcc gcaagtaaca gctatctacg
    28201 atgctgcagc tgttgcgcgc gaatatggta aaacgattat tgctgacggt gggatcaagt
    28261 attctggaga tattgtaaaa gcacttgctg caggtggaaa tgctgttatg cttggatcta
    28321 tgtttgctgg aactgatgaa gctccaggcg aaactgaaat cttccaagga cgtaaattca
    28381 agacttaccg tggtatggga tcaattgctg ctatgaagaa aggttcaagc gaccgttatt
    28441 tccaaggttc tgtcaatgaa gcaaacaagc tcgttccaga aggaattgaa ggtcgtgttg
    28501 cttataaagg agcggcagct gatattgttt tccaaatgat tggtggtatt cgctctggta
    28561 tgggttactg tggtgcagct aaccttaaag aactacacga taatgctcaa tttattgaaa
    28621 tgtctggtgc tggtttgaaa gaaagccatc ctcatgatgt gcaaattact aatgaggcac
    28681 caaattattc tatgtaaaaa acaatgaaaa gaactccagt gaaaacagga gttcttttac
    28741 aatgttgtca atttccattt acagcagctt taccatcctg aatagtgaag atacttagat
    28801 tttctggcag attttgaaga tggtctaagc ttgttgttgt gataaaggtt tggattgatt
    28861 gagaaatcgt ttctaataat tttaactgtc tagtgttgtc aagttcactc atcacatcgt
    28921 caagcagtaa tatcggagat tctgtggtaa tgctttccat taattcgatt tctgctaatt
    28981 ttatcgagag gacgagacta cgatgttgac cttggcttcc gaaactagca tccatcccat
    29041 ttatataaaa agaaatgtca tctcgatgag gaccgacacc agtattcttt ttaaataaat
    29101 ctctggatct acttttttct aaagcaattt tgaaagattc ggataagttt tgtttgtcag
    29161 ttatattgac agaagattga taggatattg acaactcttc gatctgatta gagagttcaa
    29221 aatgtttctt acgcccaaat gattctagtt tttttatgaa atctaagcgg tgattcatta
    29281 cacgacatcc ataatcaact agctgatcat ctaacacaga aaggaatgtt tcatctattt
    29341 tttgagctga ttttaggtaa gtgtttcttt gctttaggat gtggttataa ttggttaagt
    29401 cagataaata gattggctta atttgcccaa gttccatatc aatgaatttt cgtcgaatcg
    29461 aaggtgctcc tttaattagt tgtaaatctt caggagcaaa taagacaaca ttcatgtgtc
    29521 ctacataatc tgaaaggcgt gcctgtttta agtgattaac ttttgttaca cggccttttt
    29581 gtgttagttc gatttctagg ggaatggatc cagttttttt ctgaacgaga cctgaaagat
    29641 gaagttgttc ctcatcaaaa tgaatgagat ttttatctgt tcgagttcga tgactacgcg
    29701 ttaaggctaa aaaatagata gcctctaaca tgtttgtttt tccttgtgca ttacgtccca
    29761 aaaagacatt caatttagga ttaaagtcta ttttcgtttc tttgtaatta cgaaaagtct
    29821 tgagagatag atgttgtagc cacatgatta tctaccaggg aatcgtggag cttgttggct
    29881 tttaggtgat gaagcaggtt tcgatttgtc ttttttaact cccttattca tctttttgac
    29941 aagtttagcg atccgttctt tttcaacttt atcagcttgg tattcatctt gttcttcaga
    30001 agtaggttgt gtcaacaaga tgtcaatgtt catgtcaggg atgtcaactt tatcgccaat
    30061 acgaagtttt tttccacgac gactctctaa ttccctatta aagtaaacag aatgttcaga
    30121 gagaaatgat ttaatagctc ctccgctatg tgtaattcca agttctttga gtagtgcttg
    30181 gagggtaata aattcttcaa ataatttgta ttccataatt cacctcaatc tttggtatta
    30241 taccatattt tcctaaaaat agtgagagag acagcgagaa atgtaagcga tttttatttc
    30301 aaaagtgtta cagggaacaa gaaaatttca ggttttcgtg atataataga agtctgtata
    30361 taaggaggta aatcatggag ttagtgcatg gaatttcaac acattttatc caatcaaaaa
    30421 agtttaaaac aaacaaaatt accgtgcgtt ttaccgctcc attatccctt gatacgattg
    30481 caggtcacat gttgagtgca agtatgctag agactgctaa tcagatgtac cccacttctc
    30541 aagatttgag gagacacttg gccagtctat acggtacaga tatgtcaacc aattgtttca
    30601 gaagagggca aagccacatt atagaattga catttaccta tgttcgtgat gagtttttaa
    30661 gtaggaaaaa cgtgctaacc tctcagattt tggaacttgt aaaagaaact cttttttcac
    30721 ccgtagtagt tgataatggg tttgatccgg ccttatttga aattgagaaa aaacaattgc
    30781 tagcaagttt agcagctgat atggatgatt ctttttattt tgcacataaa gaattggata
    30841 aattgttttt tcatgatgaa cgtcttcaat tggaatatag tgatttacga aatcgtattt
    30901 tagctgaaac tccacaaagt tcttattctt gtttccaaga atttttagcc aatgatcgaa
    30961 tagatttctt tttcctaggt gattttaatg aggttgaaat tcaaaatgta ttagaatcat
    31021 ttggctttaa aggtcgaaaa ggagatgtga aggttcagta ttgtcaacct tattctaata
    31081 tccttcagga aggtatggtt cggaaaaatg tgggacaatc cattttggaa ttaggttatc
    31141 attaccgttc taaatatggt gatgaacaac atttacccat gattgtaatg aatggtttac
    31201 ttggtggatt tgctcactct aagctcttta caaatgtccg tgaaaatgct ggattagctt
    31261 ataccatttc aagtgagctt gatttattta gtggattctt gaggatgtat gctggtatca
    31321 atcgagaaaa tcgtaaccag gctcgtaaaa tgatgaataa tcaactgctt gatttaaaaa
    31381 aaggttattt tacagagttt gagttaaatc agaccaagga aatgattcgt tggtcgttgt
    31441 tactttctca agataatcaa tcttcattga ttgaacgtgc ttatcaaaat gccttatttg
    31501 gaaaatcttc agcagacttt aaaagttgga ttgcaaagct tgaacaaatt gacaaagatg
    31561 ctatttgtag agtagctaat aatgtgaaac tacaagcgat ttactttatg gaaggaatag
    31621 aatgacaaag gttgtttttg aagaaaaata ctatccagct gtaaaagaaa aggtttatcg
    31681 aactcgtttg gccaacggat tgacagttgc tcttttgcct aaaaaggaat ttaaagaggt
    31741 ttacgggagt gtcactgtac agtttggttc ggtagatacg tttgtcacag aagttgacgg
    31801 agatgtaaaa caatatcctg gaggaattgc tcattttctt gaacataaat tatttgagag
    31861 agaagattct agtgatttga tgtcggcttt tacgagtata ggtgcagata gtaatgcctt
    31921 tacaagcttt acaaaaacaa actatctttt ttcagcaacg gattattttt tagaaaattt
    31981 agatttactt gatgaattgg taacatcagc acactttact gaagcttcca ttctgacaga
    32041 gcaggatatt attcagcaag aacgagaaat gtaccaagat gatccagatt cgtgtttatt
    32101 cttttcaact ttagcgaatt tgtatcctgg tacaccttta gcaactgata tagttggaag
    32161 tgaggagtcc atttcccaaa tcaatctaac taatttgcaa gaaaatttta caaagtttta
    32221 caaacctgta aacatgtctc tgtttttagt tggtaatttt gatgtggagc gagtacagga
    32281 ctattttgaa agcaaagaac tgaaagattc agattttcag gaagtagcaa gagaaaagtt
    32341 gtttttacag cctgtaaagc taacagatag tatgagaatg gaagtatctt ctcccaaact
    32401 agcgattgga gttagaggta agcgagaagt ttctgaagcg gattgctatc gacatcatat
    32461 tttattaaaa ttattgtttg caatgatgtt tggttggact tcggatcgtt ttcaaaaatg
    32521 ttatgaatca ggtaaaattg atgcgtcctt atctctggaa gttgaaataa caagtcgctt
    32581 tcattttgtc atgttgacaa tggatacgaa agagccagtt gctttgtctc atcaatttag
    32641 gaaggctatt cgtaatttta caaaggattt agatattaca gaggaacatt tagatattat
    32701 caaaagagag atgtttggcg aatttttcag tagcatgaac tctcttgaat ttattgcaac
    32761 gcaatatgat gcttttgaaa atggtgagac aatttttgat ttgccgaaaa ttttacagga
    32821 aattacttta gaggatgtcc ttgatgctgg acatcattta atagatgatg gtgacatagt
    32881 tgattttaca atatttccat cgtagtaacc tatcataata gacactagaa agaagggatg
    32941 acaagtatga gaaaaaaaac aattggagag gttttacgat tagctagaat caatcaggga
    33001 ttgagtttag atgaattgca gaaaaagaca gaaatccagt tagatatgtt ggaagcaatg
    33061 gaagcagacg atttcgatca acttccaagt cctttttaca cgcgttcttt cttgaaaaaa
    33121 tatgcatggg ctgttgagtt agatgaccaa attgttttgg atgcttatga ttctgggagt
    33181 atgattactt atgaggaagt agatgttgat gaagatgagt tgacaggtcg tagacgttca
    33241 agtaagaaaa agaagaaaaa aacatcattt ttacctttat tttattttat cctttttgct
    33301 ttatcgattt taatttttgt gacttattat gtttggaact atattcaaac tcaaccagag
    33361 gagccttctc tttctaatta cagtgtggtt caatcaacaa gttcaactag ctctgttccc
    33421 cactcctcaa gtagtagttc ttctagtata gaatcagcta taagtgtatc aggcgaagga
    33481 aatcatgtag aaatcgctta taagacaagt aaggaaacag ttaaattgca attggcagtt
    33541 tcagatgtta caagttgggt cagtgtttca gaaagcgaac ttgagggcgg tgtaacctta
    33601 tcgccaaaga agaaaagtgc agaagcaaca gttgcaacta aaagtcctgt aacaattacg
    33661 ttaggtgttg taaaaggtgt tgatttgaca gtagataatc agactgttga tttatcgaaa
    33721 ttaacagctc agactggaca aatcactgta acctttacta aaaattaagg aaaaacgaat
    33781 gaaaaaagaa caaattccca atctcttaac aataggtcga attctcttta tacctatttt
    33841 tatctttatt ttaacgatag gaaattcgat agagagtcat atagttgcag ctattatctt
    33901 tgctgttgcc agtattaccg actatttaga tggatattta gctcgtaaat ggaatgtggt
    33961 cagtaatttt ggtaaatttg cagatcctat ggcggataag ttactagtta tgtcggcttt
    34021 tattatgttg attgagttag gtatggctcc ggcttggatt gttgcagtga ttatatgtcg
    34081 tgagttagct gtgacaggtt taaggctttt attggttgaa actggtggaa caattttagc
    34141 agcagcaatg cctggaaaaa ttaaaacttt tagtcagatg tttgctatta ttttcttgct
    34201 attacattgg actttgcttg gtcaagttct actttatgta gccttatttt tcactatcta
    34261 ctctggctat gactatttta agggtagtgc ctatgtattt aaagggacat ttggttcgaa
    34321 atgaaatcaa taattgatgt aaaaaatctt tcttttcgct ataaagaaaa tcagaactac
    34381 tacgatgtga aggatattac gtttcacgtg aaacgtggag aatggctttc gattgtaggg
    34441 cataatggta gtggtaaatc aacgacggtt cgattaattg atggcttact ggaagcagaa
    34501 tccggagaga ttgtaattga tggccaacgt ttgactgagg aaaatgtttg gaatatacgt
    34561 cgtcaaatcg gtatggtttt tcaaaatcca gacaatcaat ttgttggagc gactgttgaa
    34621 gatgatgttg cttttggttt ggaaaatcag ggactttctc gtcaagaaat gaaaaagaga
    34681 gtggaagaag ctctggcttt agttggcatg ttggacttta aaaagagaga gccagcgcgt
    34741 ctatcaggtg gtcaaaagca acgtgtggcc attgcaggtg ttgtagccct aagaccagct
    34801 attttaatct tagatgaagc aacgagtatg ttggatcctg aggggcgtag agaacttatt
    34861 gggacagtaa aaggaattcg aaaagactat gatatgacgg tcatttctat tacccatgat
    34921 ttggaagaag tcgccatgag tgatcgcgta ttggtcatga aaaaagggga aattgaatca
    34981 actagtagtc caagggagct tttctctcga aatgatttag atcaaattgg attagacgat
    35041 ccttttgcta atcaattaaa aaaatctttg agccagaatg gctatgattt acctgaaaat
    35101 tatttgacag aaagtgagct agaggataag ctatgggaat tgctctagaa aatgtgaatt
    35161 ttacatatca agaaggtact cccttagctt cagcagcttt gtcggatgtt tctttgacga
    35221 ttgaagatgg ctcttataca gctttaattg ggcacacagg tagtggtaaa tcaactattt
    35281 tacaactctt aaatggttta ttggtgccaa atcaagggag tgtgagggtt tttgatacct
    35341 taatcacctc gacttctaaa aataaagata ttcgtcaaat tagaaaacag gttggcttgg
    35401 tatttcagtt tgctgaaaat cagatttttg aagaaacggt tttgaaggac gttgcttttg
    35461 gaccgcaaaa ttttggagtt tctgaagaag atgctgtgaa gactgcgcgt gagaaactgg
    35521 ctctggttgg aattgatgaa tcactttttg atcgtagtcc gtttgagctg tcagggggac
    35581 aaatgagacg tgttgccatt gcaggcatac ttgccatgga gccagctata ttagtcttag
    35641 atgagccaac agctggtcta gatcctctag ggagaaaaga gttgatgacc ctgttcaaaa
    35701 aactccacca gtcagggatg accatcgtct tggtaacgca tttgatggat gatgttgctg
    35761 aatatgcgaa tcaagtctat gtaatggaaa agggacgttt agtaaagggg ggcaaaccaa
    35821 gtgatgtctt tcaagacgtt gtttttatgg aagaagttca gttgggagta cctaaaatta
    35881 cggccttttg taaacgattg gctgatagag gcgtgtcatt taaacgatta ccgattaaga
    35941 tagaggagtt caaggagtcg ctaaatggat agtatgattt tagggcgtta tatcccaggg
    36001 gattcgattg ttcaccgatt ggatccacgt agcaaattgc ttgctatgat gctactgatt
    36061 ttgattgtgt tttgggctaa taaccccttg acgaatctga ttctttttat agcgacaggg
    36121 atatttattg ccttgtcagg agtatctctt tcatttttta ttcagggctt gaagtctatg
    36181 tttttcttga ttgccttcac aactattttt caactatttt tcatttctaa tgggaatgtt
    36241 ttatttgagt tttcgtttgt gagaatcacg gattatgctt tgcaacaagc tgggattatt
    36301 ttttgtcgct ttgtattgat tattttcttt tcaactttgt taaccttaac aaccatgcct
    36361 ttaagtttgg catcagctgt cgaagcttta ttagcacctt taaagcgtgt gaaagttcca
    36421 gttcatgaaa ttggattgat gctgtctatg agtttgcgtt ttgtcccaac cttgatggat
    36481 gatacgacgc ggattatgaa tgcacagaaa gctcgtggag tggattttgg agaaggaagc
    36541 atcgttcaaa aagtaaaggc gatgattccc attttgattc ctctttttgc gacaagttta
    36601 aaacgtgcag attccttggc tatcgctatg gaagcgcgtg gctatcaggg tggaaaaggc
    36661 agaagtcaat accgacaatt gaaatggact ctaaaggata cgctgaccat tcttgttatt
    36721 ctcgtacttg gttgttgttt atttttctta aaatcttagt agctttcagg aattgataaa
    36781 aagttactgt aacagttttt gatataaagg taggaatatg aaccgtttta aaaaatcaaa
    36841 atatgtcatt attgtttttg tcactgttct gcttgtgtca gctctcttag cgacgactta
    36901 ttcaagtaca attgtgacaa aattaggaga tggaatctca ttggttgata gagttgtaca
    36961 aaaacctttt cagtggtttg attctgtcaa atcagatttg gctcatttga cacgaacata
    37021 taatgaaaat gaaagtttga agaaacagct ttaccaatta gaagttaaat caaatgaggt
    37081 ggaaagttta aagacagaaa atgaacaact gcgccaattg cttgatatga agtctaaatt
    37141 gcaagccaca aagactttag cagcagatgt tattatgcgt tctccggtat cttggaagca
    37201 ggagttgacc ttagatgcag gtagatcaaa aggtgcttct gagaacatgt tagctattgc
    37261 aaatggtggc ttgattggga gtgtttcaaa agtagaggag aactctacta tagtcaacct
    37321 tctgacaaat acggaaaatg ctgataagat ttctgttaaa attcaacatg gctctactac
    37381 aatttatgga attattattg gctatgacaa ggaaaatgac gttcttaaaa ttagccaatt
    37441 aaatagtaat agcgatatta gtgcgggaga taaggtgact actggtggat taggaaactt
    37501 taacgttgct gatattcctg ttggtgaagt ggttgccaca acgcatagta cagactattt
    37561 gacacgagaa gtaactgtta aattgagtgc agatactcat aatgtagatg tgatagaatt
    37621 agtggggaat tcataatgag acagttgaag cgagttggag tatttttatt gcttcctttc
    37681 tttgttctaa ttgacgccca tattagccag cttctgggct catttttccc ccatgtacat
    37741 ttggctagtc attttctttt tctatttctc ttatttgaga cgatagaagt atcagagtat
    37801 ctctacctag tctattgttt tgttataggc ttggtttatg atgtttactt tttccatcta
    37861 atagggatta caactctctt atttatctta ttgggagcct tccttcataa attgaatagt
    37921 gttattttgt tgaatcgttg gacaagaatg ctagctatga ttgtgctgac attcctgttt
    37981 gaaatgggta gttatctttt ggcttttatg gtagggttga cagtagatag catgtcgatt
    38041 tttatagtct atagcttggt accgacgatg attttaaatt ttttatggat tactgttttt
    38101 caatttattt ttgaaaaata ttatctataa gaacgacata taaatgtaac aaaggcgtaa
    38161 tatttattag gccttttttt ggtatactag tattgtcttt aaaagaagga gtatctacgt
    38221 aatatgaaga aaaaaatctt agcgtcactt ttattaagta cagtaatggt ttctcaagta
    38281 gctgttttaa caactgcgca tgcagaaacg actgatgaca aaattgctgc tcaagataat
    38341 aaaattagta acttaacagc acaacaacaa gaagcccaaa aacaagttga ccaaattcag
    38401 gagcaagtat cagctattca agctgagcag tctaacttgc aagctgaaaa tgatagatta
    38461 caagcagaat ctaagaaact cgagggtgag attacagaac tttctaaaaa cattgtttct
    38521 cgtaaccaat cgttggaaaa acaagctcgt agtgctcaaa caaatggagc cgtaactagc
    38581 tatatcaata ccattgtaaa ctcaaaatca attacagaag ctatttcacg tgttgctgca
    38641 atgagtgaaa tcgtatctgc aaacaacaaa atgttagaac aacaaaaggc agataaaaaa
    38701 gctatttctg aaaaacaagt agcaaataat gatgctatca atattgtaat tgctaatcaa
    38761 caaaaattgg ctgatgatgc tcaagcattg actacgaaac aggcagaact aaaagctgct
    38821 gaattaagtc ttgctgctga gaaagcgaca gctgaagggg aaaaagcaag tctattagag
    38881 caaaaagcag cagctgaggc agaggctcgt gcagctgcgg tggcagaagc agcttataaa
    38941 gaaaaacgag ctagccaaca acaatcagta cttgcttcag caaacactaa cttaacagct
    39001 caagtgcaag cagtatctga atctgcagca gcacctgtcc gtgcaaaagt tcgtccaaca
    39061 tacagtacaa acgcttcaag ttatccaatt ggagaatgta catggggagt aaaaacattg
    39121 gcaccttggg ctggagacta ctggggtaat ggagcacagt gggctacaag tgcagcagca
    39181 gcaggtttcc gtacaggttc aacacctcaa gttggagcaa ttgcatgttg gaatgatggt
    39241 ggatatggtc acgtagcggt tgttacagct gttgaatcaa caacacgtat ccaagtatca
    39301 gaatcaaatt atgcaggtaa tcgtacaatt ggaaatcacc gtggatggtt caatccaaca
    39361 acaacttctg aaggttttgt tacatatatt tatgcagatt aatttacaga gggactcgaa
    39421 tagagccctc ttttcaggtt ttaccgtgac aatccctatt aaaaattata tcaaaatagc
    39481 ttgaaaatat tggaaaagta tggtaaaatg aaaattgtcg tgtgaacgat aatactcatt
    39541 cttgatgaat tgtgaagcag ttgcccttgg gtcgttttgc gagttgaagt caagaagagg
    39601 aaaaaaacaa aaaggagaaa tactcatggc agtaatttca atgaaacaac ttcttgaggc
    39661 tggtgtacac tttggtcacc aaacccgtcg ctggaatcct aagatggcta agtacatctt
    39721 tactgaacgt aacggaatcc acgttatcga cttgcaacaa actgtaaaat acgctgacca
    39781 agcatacgac ttcatgcgtg atgcagcagc taacgatgca gttgtattgt tcgttggtac
    39841 taagaaacaa gcagctgatg cagttgctga agaagcagta cgttcaggtc aatacttcat
    39901 caaccaccgt tggttgggtg gaactcttac aaactgggga acaatccaaa aacgtatcgc
    39961 tcgtttgaaa gaaattaaac gtatggaaga agatggaact ttcgaagttc ttcctaagaa
    40021 agaagttgca cttcttaaca aacaacgtgc gcgtcttgaa aaattcttgg gtggtatcga
    40081 agatatgcct cgtatcccag atgtgatgta cgtagttgac ccacataaag agcaaatcgc
    40141 tgttaaagaa gctaaaaaat tgggaatccc agttgtagcg atggttgaca ccaatactga
    40201 tccagatgat atcgatgtaa tcatcccagc taacgatgac gctatccgtg ctgttaaatt
    40261 gatcacagct aaattggctg acgctattat cgaaggacgt caaggtgagg atgcagtagc
    40321 agttgaagca gaatttgcag cttcagaaac tcaagcagat tcaattgaag aaatcgttga
    40381 agttgtagaa ggtgacaacg cttaatttat acaaatagta attacctagg agggcggggc
    40441 ttagcccggc tctcctattt tcaaaaaata taggagaatt aaaatggcag aaattacagc
    40501 taaacttgta aaagagttgc gtgaaaaatc tggtgccggt gttatggacg ctaaaaaagc
    40561 gcttgtagaa acagacggtg acatcgaaaa agcgattgaa ttgcttcgtg aaaaaggtat
    40621 ggctaaggca gctaagaaag ctgaccgtgt tgctgcagaa ggtttgactg gtgtttatgt
    40681 taacggtaat gttgcagcag ttattgaagt aaacgctgaa actgacttcg ttgcaaaaaa
    40741 cgctcaattc gttgaattgg taaatactac agccaaagtc attgctgaag gaaaacctgc
    40801 taacaatgaa gaagctcttg ctttgataat gccttcaggt gaaactcttg aagctgcata
    40861 cgtatctgca acagcaacta tcggagagaa aatctcattc cgtcgctttg cattgattga
    40921 aaaaacagac gcacaacact ttggagcata ccaacataac ggtggacgta tcggtgttat
    40981 ttcagttgtt gaaggtggag acgaagcact tgctaaacaa ttgtcaatgc acatcgcagc
    41041 gatgaaacca acagttcttt cttacaaaga attggatgag caattcgtta aagatgagtt
    41101 ggcacaattg aatcacgtta tcgaccaaga caacgaaagc cgtgcaatgg ttaataaacc
    41161 agctcttcca cacttgaagt atggatcaaa agctcaatta actgatgatg ttattgctca
    41221 agctgaagct gacatcaaag ctgaattggc tgcagaaggc aaaccagaaa aaatctggga
    41281 caaaattatt ccaggtaaaa tggatcgctt catgcttgat aacactaaag ttgaccaagc
    41341 ttacacactt cttgcacaag tttacatcat ggatgacagc aagacagttg aagcatacct
    41401 tgaatcagtt aacgcttcgg tagttgagtt tgctcgcttt gaagttggtg aaggtatcga
    41461 gaaagctgca aacgacttcg aagctgaagt tgcagctaca atggcagcag ccttgaataa
    41521 ctaataatag aaaggaagca aattgcttcc ttttttgtat gcagtcgatc cttataggga
    41581 gagcttccta ttttcaaggt aaaaataaaa agccctataa taagggccaa ttgtatttag
    41641 gagactaaac ttcaaattca tagagtgctg tagagagata acgttcaccg ttatctggtg
    41701 ctagagcaag gactttttta cctgtaccta attttttggc aacctcgatg gctccgtaga
    41761 tagctgcagc tgaggaaatc cctacaagga agccttcttt tccaccaatt tcacgtccga
    41821 gtgcaagagc atcatctgat gttacacgaa cgatactatc ataggcttta gtatcaagtg
    41881 tatcaggaat aaatccagct gagatacctt gaattttgtg aggaccaggt ttttcaccag
    41941 atagaatagc agattcatca gcttccactg cataaacttg aatgttagaa ttttctgatt
    42001 tgagtgcatg agaaacacca gaaatcgttc caccggtacc tactccagca acaaaggcat
    42061 ctaatccatc tttaccgaaa gcagctagta tctcagctcc tgttgttctt tcgtgtactt
    42121 ctggattagc tggattgtca aattgaagag gaaggaaacc atcacgttca gcagcgattt
    42181 cttgagcctt agcaatagca cctttcattc cctcgctacc aggagttagg acgagttcag
    42241 caccataagc ttggataatt ttacgtcgtt ctacactcat agtttcaggc ataacgatga
    42301 cgactttata ccctttagca gcacctaccc atgaaagtcc aataccagtg tttccacttg
    42361 ttgcttcaac aatagtagaa ccaggtttca gaataccatc ttgttcagct ttttcaatca
    42421 tgctaagggc aatacggtct tttacagatg aaccaggatt aaatgcttca agctttatat
    42481 agacgtctgc agcaccttct ggcacgatgt tgttaagttt aacaatcggt gtttgaccga
    42541 ttaattcagt aatgttgtta taaatagaca tatgaatacc tctttgtata agatatcttt
    42601 agtataacgc tatctatacc atttgtaaaa tatagaaatc ctatcgaagc gataggattt
    42661 ctatatatca tagatcaaag tcattaattt tcaagtgatt gcgttcagct aattctagta
    42721 aataggtgtg aaggaaaacg atatcaggtt tcgtttgaat tgcttcattt tctagtatat
    42781 tttggtacgc atctttttat tttgctcgct aaagtagttg tgagaatgtc aacgaaacgc
    42841 tgtattattc attgtttaca ctaagtttac aggaacttca acctctcgta aaccttggtc
    42901 agttaaagtg acttttccat taaaaaactc cacaagtgca gctttaatag tttctttttc
    42961 ttccttatca acataaatca tcgtatcgac ttgatctgta aagtttgtat ccagctccat
    43021 gagatcatgt tctttaagga agttactgta ctcttggtac tgagcataag acatttgaat
    43081 agcaatgcca gcctgttctt ttatttcaat aataccaatt tctttgacag ctaaggcgac
    43141 actgccggcg taagcacgaa ttagtcctcc agcgcctagt ttaataccac caaagtagcg
    43201 tgtcacgacc acacagacat tggtgagatt gtgattttct agtaccccaa gcatgggaac
    43261 accagcagta ccactaggct caccatcatc acttgtacgt ttaatttcac tacgttctcc
    43321 aataataaag gcagagcagt tatgtgtcgc tttgtagtgt tcttttttga tggcagtaat
    43381 gaagtcacga gcctcttctt cgctataaac acgcttggca tggcagataa agcgagattt
    43441 tttgatttct tcttggactt ggccgtcctc tttaattgtc ctaaattcca tgatttaatt
    43501 gtactaaaaa ataatctaaa gtgctagttt ttacgaataa agaagtatga aagtaaattt
    43561 agattatctc ggtcgtttat ttactgagaa tgaattaaca gaagaagaac gtcagttggc
    43621 ggagaaactt ccagcaatga gaaaggagaa ggggaaactt ttctgtcaac gctgtaatag
    43681 tactattcta gaagaatggt atttgcccat cggtgcttac tattgtcgag agtgcttgct
    43741 gatgaagcga gtcagaagtg atcaaacttt atactatttt ccgcaggagg attttccgaa
    43801 gcaagatgtt ctcaaatggc gcggccaatt aactcctttt caagagaagg tgtcagaggg
    43861 actgcttcaa gcagtagaca agcagaagcc aaccttagtt catgcggtaa caggagctgg
    43921 aaagacagaa atgatttatc aagtagtggc taaagtgatc aatgcgggtg gtgcagtgtg
    43981 tttggctagt cctcgcatag atgtttgttt ggagctgtac aagcgcctgc aacaggattt
    44041 ttcttgcggt atagctttgc tacatggaga atcggaacct tattttcgaa caccactagt
    44101 tgttgcaaca acccatcagt tattgaagtt ttatcaagct tttgatttgc tgatagtgga
    44161 tgaagtagat gcttttcctt atgttgataa tcccacgctt taccacgctg tcaagaatag
    44221 tgtaaaggag aatggattga gaatcttttt aacagcgact tcgaccaatg agttagataa
    44281 aaaggtccgt ttaggagaac taaaaagact gagtttaccg agacggtttc atggaaatcc
    44341 gttgattatt ccaaaaccaa tttggttatc ggattttaat cgctacttag acaagaatcg
    44401 tttgtcacca aagttaaagt cctatattga gaagcagaga aagacagctt atccgttact
    44461 catttttgct tcggaaatta agaaagggga gcagttagaa gaaatcttac aggagcaatt
    44521 tccaaatgag aaaattggct ttgtatcttc tgtaacagag gatcgattag agcaagtaca
    44581 agcttttcga gatggagaac tgacaatact tatcagtacg acaatcttgg agcgtggagt
    44641 taccttccct tgtgtggatg ttttcgtaat agaggccaat catcgtttgt ttaccaagtc
    44701 tagtttgatt cagattggtg gacgagttgg acgaagcatg gatagaccga caggagattt
    44761 gcttttcttc catgatgggt taaatgcttc aatcaagaag gcgattaagg aaattcagat
    44821 gatgaataag gaggctggtc tatgaagtgc ttgttatgtg ggcagactat gaagactgtt
    44881 ttaactttta gtagtctctt acttctgagg aatgatgact cttgtctttg ttcagactgt
    44941 gattctactt ttgaaagaat tggggaagag aactgtccaa attgtatgaa aacagagttg
    45001 tcaacaaagt gtcaagattg tcaactttgg tgtaaagaag gagttgaagt cagtcataga
    45061 gcgattttta cttacaatca agctatgaag gattttttca gtcggtataa gtttgatgga
    45121 gacttcctgt taagaaaagt tttcgcttca tttttaagtg aggagttgaa aaagtacaaa
    45181 gagtatcaat ttgttgtaat tcccctaagt cctgatagat atgctaacag aggatttaat
    45241 caggttgagg gcttggtaga ggcagcaggc tttgagtatc tagatttatt agagaaaaga
    45301 gaagagagag ccagttcttc taaaaatcgt tcagagcgct tggggacaga acttcctttc
    45361 tttattaaaa gtggagtcac tattcctaaa aaaatcctac ttatagatga tatctatact
    45421 acaggagcaa ctataaatcg tgttaagaaa ctgttggaag aagccggtgc taaggatgta
    45481 aaaacatttt cccttgtaag atgaggaaaa aatttgcaaa aatagaatga aagcgttata
    45541 ataaaatcat aaaaacaaaa atgtttagaa agaaggtatt catatgatta aatatagtat
    45601 ccgtggtgaa aacctagaag taacagaagc aattcgtgat tatgtagttt ctaaactcga
    45661 aaagatcgaa aagtacttcc aaccagaaca agagttggat gcccgaatta acttaaaagt
    45721 ttatcgtgaa aaaacggcta aagtggaagt aacgattccg cttggatcta ttactctccg
    45781 cgcagaagat gtatctcaag atatgtatgg ttcaattgac cttgtaactg ataaaattga
    45841 acgtcagatt cgtaaaaata aaacaaaaat cgagcgtaaa aataaaaata aggtagcaac
    45901 tggtcaatta tttacagatg ctttggtgga agattcaaat gttgtccagt ctaaagttgt
    45961 tcgttcaaaa caaattgatt taaaaccaat ggatttggaa gaagcaattc tacaaatgga
    46021 tttattgggg catgatttct ttatctatgt ggatgttgaa gatcagacaa ccaatgtgat
    46081 ttatcgtcgt gaggatggcg aaattggttt gttagaggtt aaagaatctt aatttcaata
    46141 tgtgtaaagg taggtttact gaattgtaaa ctaccttttt cttataattg atagaattac
    46201 tgattacacc tttaaaaagt cgctttttga ggggtattat ggtataatgg gtgccaagag
    46261 gttttgaatg aaaaaatttt atgtaagtcc aatttttcct attctagtag gattgattgc
    46321 gtttggagtc ttatccactt tcattatttt tgttaataat aatctgttga cggttttaat
    46381 tttgtttctt tttgtaggag gctatgtttt tttatttaag aaactgagag tgcattatac
    46441 aaggagtgat gtagaacaga tacagtatgt aaaccaccaa gcggaagaaa gtttgacatc
    46501 tctattggaa caaatgcctg taggtgttat gaaattgaat ttatcttctg gagaggttga
    46561 gtggtttaat ccctatgctg aattgatttt gaccaaggaa gatggtgatt ttgatttaga
    46621 agctgttcaa acgattatca aggcttcagt aggaaatccg tctacttatg ccaagcttgg
    46681 tgagaagcgt tatgctgttc atatggatgc ttcttccggt gttttgtatt ttgtagatgt
    46741 atccagggaa caagccataa cagatgaatt ggtaacaagt cgaccagtga ttgggattgt
    46801 ctctgtggat aattatgatg atttggagga tgcaacttct gagtcagata ttagtcaaat
    46861 caatagtttt gtagctaatt ttatatcaga gttttcagaa aaatacatga tgttttctcg
    46921 tcgggtaagt atggatcgat tttatctatt tactgactac acggtgcttg agggcttgat
    46981 gaatgataaa ttttctgtta ttgatgcttt cagagaagag tcgaaacaga gacagttgcc
    47041 cttgacctta agtatgggat tttcttatgg cgatggaaat catgatgaga tagggaaagt
    47101 tgctttgctc aatttgaact tggctgaagt acgtggtggc gaccaggtgg ttgttaagga
    47161 aaacgacgaa acgaaaaatc cagtttattt tggtggtggg tctgctgctt caatcaagcg
    47221 tacacggact cgtacgcgcg ctatgatgac agctatttca gataagattc ggagtgtaga
    47281 tcaggttttt gtagtcggtc acaaaaattt agacatggat gctttgggct ctgctgtagg
    47341 tatgcagttg ttcgccagca atgtgattga aaatagctat gctctttatg atgaagaaca
    47401 aatgtctcca gatattgaac gagctgtttc attcatagaa aaagaaggag ttacgaagtt
    47461 gttgtctgtt aaggatgcaa tggggatggt gaccaatcgt tctttgttga ttcttgtaga
    47521 ccattcaaag acagccttaa cattatcaaa agaattttat gatttattta cccaaaccat
    47581 tgttattgac caccatagaa gggatcagga ttttccagat aatgcagtca ttacttatat
    47641 cgaaagtggt gcaagtagtg ccagtgagtt ggtaacggaa ttgattcagt tccagaattc
    47701 taagaaaaat cgtttgagtc gtatgcaagc aagtgttttg atggctggta tgatgttgga
    47761 tactaaaaat ttcacctcgc gagtaactag tcggacattt gatgttgcta gctatctcag
    47821 aacgcgcgga agtgatagta ttgctatcca ggaaatcgct gcgacagatt ttgaagaata
    47881 tcgtgaggtc aatgaactta ttttacaggg gcgtaaatta ggttcagatg tactaatagc
    47941 agaggctaag gacacgaaat gctatgatac agttgttatt agtaaggcag cagatgccat
    48001 gttagccatg tcaggtattg aagcgagttt tgttcttgcg aagaatatac aaggatttat
    48061 ctctatctca gctcgaagtc gtagtaaact gaatgtacaa cggattatgg aagagttagg
    48121 cggtggaggc cactttaatt tggcagcagc tcaaattaaa gatgtaacct tgtcagaagc
    48181 aggtgaaaaa ctgacagaaa ttgtattaaa tgaaataaag gaaaaggaga aagaagaatg
    48241 aaagtaatct ttttagcaga tgttaaagga aaaggtaaaa aaggcgaaat taaggaagta
    48301 ccaacagggt atgcgcaaaa ttttcttatc aaaaagaatc tagccaaaga agcgactgct
    48361 caagctgtag gtgaacttcg tggtaaacaa aaatcggaag aaaaagctca cgctgagatg
    48421 attgcagaag gaaaagcaat taaagcacaa cttgaagcag aagaaactgt tgtagaattt
    48481 gttgaaaaag ttggtccaga tggtcgtacc tttggttcta ttaccaataa gaagattgca
    48541 gaagaattgc aaaagcaatt tggaattaag attgataaac gtcatattca agtacaagct
    48601 ccgattcgag cggttggttt gattgatgtg ccagtgaaaa tctatcaaga tatcacaagt
    48661 gtaatcaatc ttcgtgtgaa agaaggataa gtttacacct tcttgacaag attgtaaaag
    48721 gaagggaagt ctgatggcag aagtagaaga gttacgagta caacctcaag atatcttagc
    48781 tgagcaatcc gttttagggg ctatctttat tgatgagagt aaacttgttt ttgtgcgaga
    48841 atacattgag tctcgggact tttttaagta tgcccatcgt ttgattttcc aagccatggt
    48901 cgatttatcc gatcgtggtg atgccataga tgcaacaacg gttcgtacta tccttgataa
    48961 tcaaggtgat ttacagaata ttggtggctt gtcttacttg gttgagattg ttaattctgt
    49021 gccaacttct gctaatgcgg agtattatgc taagattgtt gcagaaaaag caatgctacg
    49081 tcgtttaatt gccaagttga cagagtctgt caaccaagct tacgaagcgt cacaaccagc
    49141 tgatgaaatt attgctcagg cagaaaaagg gttgattgat gtcagtgaaa atgcaaatcg
    49201 aagcgggttt aagaacattc gagatgtgtt gaatctcaac tttggaaatc tggaagctcg
    49261 ctcgcaacaa acgaccgata ttacaggtat tgcgacaggt tatcgtgatt tggatcatat
    49321 gacaacagga cttcatgagg aggagttgat tatcttagca gctcgtccag cagttggtaa
    49381 gacagcattt gccttgaata tcgctcagaa tattgggact aagttggaca aaacggttgc
    49441 tattttttca ctcgaaatgg gtgcggaaag cttggtagac cgtatgttag ctgcagaagg
    49501 cttggtggag tcacattcta tccgtacagg gcaattgaca gatgaggagt ggcaaaaata
    49561 tactattgct cagggtaatc tagctaacgc cagtatctat atcgatgata cgccaggtat
    49621 tcggattaca gagattcgtt ctcgttctcg taaattggct caagaaactg gaaatcttgg
    49681 tttgattttg atagactatt tgcaacttat cacgggaact ggtcgagaaa atcgtcaaca
    49741 agaagtttct gaaatttctc gtcagttgaa aatactagcc aaggaattga aggttccagt
    49801 aatcgctctg agtcagcttt ctcgtggtgt agaacaacgt caggacaaga gaccggtctt
    49861 gtctgatatt cgtgaatctg ggtctattga gcaggacgct gatatcgtag cttttctcta
    49921 tcgcgatgac tactatgaac gtggtggtga agaagaggag ggtatcccaa ataataaggt
    49981 ggaagttatt atcgagaaaa accgtagtgg agctcgtgga acagtggaat tgattttcca
    50041 aaaagaatac aataaatttt caagtatctc aaagagggag gcataagatg tcagatgcat
    50101 ttacagatgt agccaagatg aaaaaaatca aagaagaaat caaggcacat gagggacaag
    50161 tcgtagaaat gactttggag aatggtcgta agcgccaaaa aaatagattg ggtaagctaa
    50221 ttgaagttta tccatcccta tttattgtgg agtttgggga tgtggaagga gataaacaag
    50281 ttaatgttta cgttgaatcc tttacttact cagatattct tacagaaaag aatttgattc
    50341 attatcttga ctaaagtgag aaattttctc actttttctt ttttctccga ataatttagg
    50401 tgaaggcaat catcgcttta tattattttt caaggaggaa gaatgaaaat tttaccgttt
    50461 atagcaagag gaacaagtta ttacttgaag atgtcagtta aaaagcttgt tcctttttta
    50521 gtagtaggat tgatgctagc agctggtgat agtgtctatg cctattccag aggaaatgga
    50581 tcgattgcgc gtggggatga ttatcctgct tattataaaa atgggagcca ggagattgat
    50641 cagtggcgca tgtattctcg tcagtgtact tcttttgtag cctttcgttt gagtaatgtc
    50701 aatggttttg aaattccggc agcttatgga aatgcgaatg aatggggaca tcgtgctcgt
    50761 cgggaaggtt atcgtgtaga taatacaccg acgattggtt ccattacttg gtctactgca
    50821 ggaacttatg gtcatgttgc ctgggtgtca aatgtaatgg gagatcagat tgagattgag
    50881 gaatataact atggttatac agaatcctat aataaacgag ttataaaagc aaacacgatg
    50941 acaggattta ttcattttaa agatttggat ggtggcagtg ttgggaatag tcaatcctca
    51001 acttcaacag gcggaactca ttattttaag accaagtctg ctattaaaac tgaaccccta
    51061 gttagtgcaa ctgtgattga ttactattat cctggagaga aggttcatta tgatcagata
    51121 cttgaaaaag acggctataa gtggttgagt tatactgcct ataatggaag ctatcgttat
    51181 gttcaattgg aggctgtgaa taaaaatcct ctaggtcatt ctgttctttc ttcaacagga
    51241 ggaactcatt attttaagac caagtctgct atcaaaactg aacccctagt tagtgcaact
    51301 gtgattgatt actattatcc tggagagaag gttcattatg atcagatact tgaaaaagac
    51361 ggctacaagt ggttgagtta tacggcttat aacggaagtc gtcgctatat acagctagag
    51421 ggagtgactt cttcacaaaa ttatcagaat caatcaggaa atatctctag ctatggatcc
    51481 aataatagtt caactgtcgg ttggaagaaa ataaatggta gttggtatca tttcaaatca
    51541 aatggttcta aatcaacagg atggctgaaa gacggttcta gctggtatta tttgaaatta
    51601 tctggtgaaa tgcagacagg atggttaaag gagaatggct cgtggtatta tctgggtagt
    51661 tcaggggcaa tgaaaacagg ctggtaccag gtctctggta agtggtatta ttcttactct
    51721 tcaggcgcct tagctgttaa tacgacggtg gatggctaca gagtaaacag tgatggagaa
    51781 cgagtataga aaattggagt aggagaaatt tcctgctctt ttctgtaagc agtttccttg
    51841 acatttttct tattttgcgc tatcatatat acatataata tatgggagtc tgtgtacagt
    51901 ctgagaggaa gtgttaaact tcgaccgcac ctgatctggg taatgccagc ggagggaacg
    51961 atacttagtc taattttgca ccttttccat gtatggtaaa ggtttttctt ttttttttaa
    52021 aaggaaaacg agaagaggag gttcttatga aagcaagcat tgccttgcaa gttttacccc
    52081 tagcacaggg gattgatcgg atagctgtta ttgatcaggt cattgcttat ctgcaaactc
    52141 aagaagtgac gatggtagtg acaccatttg aaacggtctt ggaaggggag tttgatgagc
    52201 ttatgcgcat tctaaaagaa gcgctggaag tggcagggca ggaggcagac aatgtctttg
    52261 ccaatgtcaa aataaatgta ggagagattt taagtattga tgagaaactt gagaagtata
    52321 ctgagacgcc acattagtct attgggcttt ctcggagtct tgtcaatctg gcagttagca
    52381 ggttttctta aacttctccc caagtttatc ctgccgacac ctcttgaaat tctccagccc
    52441 tttgttcgtg acagagaatt tctctggcac catagctggg cgaccttgag agtggcttta
    52501 ctggggctga ttttgggagt tttgattgcc tgtcttatgg ctgtgctcat ggatagtttg
    52561 acttggctca atgacctgat ttaccctatg atggtggtca ttcagaccat tccgaccatt
    52621 gccatagctc ctatcctggt cttgtggcta ggttatggga ttttgcccaa gattgtcttg
    52681 attatcttaa cgacaacctt tcccatcatc gttagtattt tggacggttt taggcattgc
    52741 gacaaggata tgctgacctt gtttagtctg atgcgggcca agccttggca aatcctgtgg
    52801 cattttaaaa ttccagtcag cctgccctac ttttatgctg gtctgagggt cagtgtctcc
    52861 tacgctttta tcacaacagt ggtatctgag tggttgggag gctttgaggg gcttggtgtt
    52921 tatatgattc agtccaagaa attgtttcag tatgatacca tgttcgctat tattattctg
    52981 gtatcgatta tcagcctttt gggtatgaag ttggtcgata ttagtgaaaa atatgtgatt
    53041 aaatggaaac gttcgtagaa ttagaatgtt tctgaaaaag aaaagaggaa atcaaaatga
    53101 agaaaacatg gaaagtgttt ttaacgcttg taacagctct tgtagctgtt gtgcttgtgg
    53161 cctgtggtca aggaactgct tctaaagaca acaaagaggc agaacttaag aaggttgact
    53221 ttatcctaga ctggacacca aataccaacc acacagggct ttatgttgcc aaggaaaaag
    53281 gttatttcaa agaagctgga gtggatgttg atttgaaatt gccaccagaa gaaagttctt
    53341 ctgacttggt tatcaacgga aaggcaccat ttgcagtgta tttccaagac tacatggcta
    53401 agaaattgga aaaaggagca ggaatcactg ccgttgcagc tattgttgaa cacaatacat
    53461 caggaatcat ctctcgtaaa tctgataatg taagcagtcc aaaagacttg gttggtaaga
    53521 aatatgggac atggaatgac ccaactgaac ttgctatgtt gaaaaccttg gtagaatctc
    53581 aaggtggaga ctttgagaag gttgaaaaag taccaaataa cgactcaaac tcaatcacac
    53641 cgattgccaa tggcgtcttt gatactgctt ggatttacta cggttgggat ggtatccttg
    53701 ctaaatctca aggtgtagat gctaacttca tgtacttgaa agactatgtc aaggagtttg
    53761 actactattc accagttatc atcgcaaaca acgactatct gaaagataac aaagaagaag
    53821 ctcgcaaagt catccaagcc atcaaaaaag gctaccaata tgccatggaa catccagaag
    53881 aagctgcaga tattctcatc aagaatgcac ctgaactcaa ggaaaaacgt gactttgtca
    53941 tcgaatctca aaaatacttg tcaaaagaat acgcaagcga caaggaaaaa tggggtcaat
    54001 ttgacgcagc tcgctggaat gctttctaca aatgggataa agaaaatggt atccttaaag
    54061 aagacttgac agacaaaggc ttcaccaacg aatttgtgaa ataatgacag aaattagact
    54121 agagcacgtc agttatgcct atggtcagga gaggatttta gaggatatca acctacaggt
    54181 gacttcaggc gaagtggttt ccatcctagg cccaagtggt gttggaaaga ccaccctctt
    54241 taatctaatc gctgggattt tagaagttca gtcagggaga attgtccttg atggtgaaga
    54301 aaatcccaag gggcgcgtga gttatatgtt gcaaaaggat ctgctcttgg agcacaagac
    54361 ggtgcttgga aatatcattc tgcccctctt gattcaaaag gtggataagg cagaagctat
    54421 ttcccgagcg gataaaattc ttgcgacctt ccagctgaca gctgtaagag acaagtatcc
    54481 tcatgaactt agcggtggga tgcgccagcg tgtagcctta ctccggacct acctttttgg
    54541 gcacaagctc tttctcttag atgaggcctt tagcgccttg gatgagatga caaagatgga
    54601 actccacgct tggtatcttg agattcacaa gcagttgcag ctaacaaccc tgatcatcac
    54661 gcatagtatt gaggaggccc tcaatctcag cgaccgcatc tatatcttga aaaatcgccc
    54721 tgggcagatt gtttcagaaa ttaaactaga ttggtctgaa gatgaggaca aggaagtcca
    54781 aaagattgcc tacaaacgtc aaatcttggc agaattaggc ttagataagt agaaaaatag
    54841 ggagttggtg aagattatcc tttaccagcg ccctttttct tttaaaaatg agaaaatttc
    54901 ggtataatag tcaaacaagg tcaaggttta aagagagagg tgggtttgtt atgagattta
    54961 aaaatacatc ggatcatatt gaggcctaca tcaaggcgat tttagatcaa tctggtatcg
    55021 tggagttgca acggagtcag ttggcagata cctttcaggt tgttcctagt cagattaact
    55081 acgtgatcaa gacacgcttt acggaaagta gaggctactt ggttgaaagt aagcgtggtg
    55141 gcggaggcta cattcgtata ggacggattg agttttctag tcatcatgaa atgctccggg
    55201 agctgcttta ctcgattggt gagcgagtca gtcaagaaat ttatgaggat attctccagc
    55261 ttttggttga gcaggaattg atgaccaagc aggagatgaa tttgctagaa tcagtagctt
    55321 tggatcgcgt tttaggagaa gaagctccag ttgttcgagc aaacatgcta cgtcagatca
    55381 tacaagaggt agatagaaaa gggaagtaag atgaactatt caaaagcatt gaatgaatgt
    55441 atcgaaagtg cctacatggt tgctggacat tttggagctc gttatctaga gtcttggcac
    55501 ttgttgattg ccatgtctaa tcacagttat agtgtagcag gggcaacttt aaatgattat
    55561 ccgtatgaga tggaccgttt agaagaggtg gctttggaac tgactgaaac ggactatagc
    55621 caggatgaaa cctttacgga attgccgttc tcccgtcgtt tgcaggttct ttttgacgaa
    55681 gcagagtatg tagcgtcagt ggtccatgct aaggtgctag ggacagagca cgtcctctat
    55741 gcgattttgc atgatggcaa tgccttggcg actcgtatct tggagagggc tggtttttct
    55801 tatgaagaca agaaagatca ggtcaagatt gctgctcttc gtcgaaattt agaagaacgg
    55861 gcaggctgga ctcgtgaaga tctcaaggct ttacgccaac gccatcgtac agtagctgac
    55921 aagcaaaatt ctatggccaa tatgatgggc atgccgcaga ctcctagtgg tggtctcgag
    55981 gactatacgc atgatttgac agagcaagcg cgttctggca agttagaacc agtcatcggt
    56041 cgggacaagg aaatctcacg tatgattcaa atcttgagcc ggaagactaa gaacaaccct
    56101 gtcttggttg gggatgctgg tgtcgggaaa acagctctgg cgcttggtct tgctcagcgt
    56161 attgctagtg gtgacgtgtc tgcggaaatg gctaagatgc gcgtgttaga acttgatttg
    56221 atgaatgtcg ttgcagggac acgcttccgt ggtgactttg aagaacgcat gaataatatc
    56281 atcaaggata ttgaagaaga tggccaagtc atcctcttta tcgatgaact ccacaccatc
    56341 atgggttctg gtagcgggat tgattcgact ctggatgcgg ccaatatctt gaaaccagcc
    56401 ttggcgcgtg gaactttgag aacggttggt gccactactc aggaagaata tcaaaaacat
    56461 atcgaaaaag atgcggcact ttctcgtcgt ttcgctaaag tgacgattga agaaccaagt
    56521 gtggcagata gtatgactat tttacaaggt ttgaaggcga cttatgagaa acatcaccgt
    56581 gtacaaatca cagatgaagc ggttgaaaca gcggttaaga tggctcatcg ttatttaacc
    56641 agtcgtcact tgccagactc tgctatcgac ctcttggacg aagcagcagc aacagtgcaa
    56701 aataaggcaa agcatgtaaa agcagacgat tcagatttga gtccagctga caaggccctg
    56761 atggatggca agtggaaaca ggcagcccag ctaatcgcaa aagaagagga agtacctgtc
    56821 tacaaagact tggtgacaga gtctgatatt ttgaccacct tgagtcgctt gtcaggaatc
    56881 cccgttcaaa aactgactca aacggatgct aagaagtatt taaatcttga agcagaactc
    56941 cataaacgtg tcatcggtca agatcaagct gtttcaagca ttagtcgtgc cattcgccgt
    57001 aatcagtcag gaattcgcag tcacaagcgt ccgatcggtt cctttatgtt cctaggaccc
    57061 acaggtgtcg gtaagaccga gttggccaag gctttggcag aagttctctt tgatgacgaa
    57121 tcagccctta tccgctttga tatgagtgag tatatggaga aattcgcagc cagccgtcta
    57181 aatggagctc ctccaggcta tgtgggttac gaagaaggtg gggagttgac agagaaggtt
    57241 cgcaataaac cctattccgt tctcctcttt gatgaggtag agaaggctca cccagatatc
    57301 tttaatgttc tcttgcaggt tctggatgac ggtgtcttga cagatagcaa gggacgcaag
    57361 gtcgattttt caaataccat tatcattatg acatcgaacc taggtgcgac tgcccttcgt
    57421 gatgataaga ctgttggttt tggggctaag gatattcgtt ttgaccagga aaatatggaa
    57481 aaacgcatgt ttgaagaact gaaaaaagct tatagaccgg aattcatcaa ccgtattgat
    57541 gagaaggtgg tcttccatag cctatctagt gaccatatgc aggaagtggt gaagattatg
    57601 gtcaagcctt tagtggcaag tttggctgaa aaaggcattg acttgaaatt acaagcttca
    57661 gctctgaaat tgttagcaaa tcaaggatat gacccagaga tgggagctcg cccacttcgc
    57721 agaaccctgc aaacagaagt ggaggacaag ttggcagaac ttcttctcaa gggagattta
    57781 gtggcaggca gcacacttaa gattggtgtc aaagcaggcc agttaaaatt tgatattgca
    57841 taaaagaata aaagtatcag catctgacca taagtcacag tggagtgaaa ctcaatgaaa
    57901 atcaaagagc aaactaggca gctagccgca ggttgctcaa aacactggtt tgaggttgta
    57961 gatagagctg acgtggtttg aagagatttt cgaagagtat aagctgcaag atgaatgatt
    58021 ttcttgtatt gacgttgttg ttgacaaaaa gtagcggata aatgaaatcc attccattat
    58081 catagatgat aggctggtag gaaattttca aatagcatat aggaaataga tgtatggagt
    58141 tctggtagta gaaagggaga gagatgaaca ttttagttgc agatgacgag gaaatgatta
    58201 gagaaggaat tgcagcattt ctgacagaag agggttatca tgtcattatg gctaaggatg
    58261 gacaagaggt cttggaaaaa tttcaagatc tccctatcca tctcatggta ctggatttaa
    58321 tgatgcctag gaagagtggt tttgaagtgt taaaagaaat caatcaaaag cacgatattc
    58381 ctgtcatcgt cttgagtgct ctgggagatg aaactactca gtcacaggta tttgatctct
    58441 atgctgatga tcatgtgaca aaaccttttt ctttggtact gcttgtcaag cgtattaagg
    58501 cgcttatcag acgttactac gtcatagagg atctttggcg atatcaggat gtaacagtgg
    58561 attttacctc ttacaaagca cattataaaa atgaagaaat tgatctcaaa ccaaaggaat
    58621 tactggtact aaagtgtttg attcagcata aaaatcaagt tttaagtaga gagcagatat
    58681 tggaagaaat ttcaaaagat gtagctgatt taccttgtga tagggtcgtt gatgtctata
    58741 ttcgtactct tcgcaaaaaa ttagctttag attgtatcgt gactgtgaaa aatgttgggt
    58801 ataagattag cttatgataa aaaatcctaa attattaacc aagtcttttt taagaagttt
    58861 tgcaattcta ggtggtgttg gtctagtcat tcatatagct atttatttga cctttccttt
    58921 ttattatatt caactggagg gggaaaagtt taatgagagc gcaagagtgt ttacggagta
    58981 tttaaagact aagacatctg atgaaattcc aagcttactc cagtcttatt caaagtcctt
    59041 gaccatatct gctcacctta aaagagatat tgtagataag cggctccctc ttgtgcatga
    59101 cttggatatt aaagatggaa agctatcaaa ttatatcgtg atgttagata tgtctgttag
    59161 tacagcagat ggtaaacagg taaccgtaca atttgttcac ggggtggatg tctacaaaga
    59221 agcaaagaat attttgcttt tgtatctccc atatacattt ttggttacaa ttgctttttc
    59281 ctttgttttt tcttattttt atactaaacg cttgctcaat cctctttttt acatttcaga
    59341 agtgactagt aaaatgcaag atttggatga caatattcgt tttgatgaaa gtaggaaaga
    59401 tgaagttggt gaagttggaa aacagattaa tggtatgtat gagcacttgt tgaaggttat
    59461 tcatgaattg gaaagtcgta atgagcaaat tgtaaaattg caaaatcaaa aggtttcctt
    59521 tgtccgcgga gcatcacatg agttgaaaac ccctttagcc agtcttagaa ttatcctaga
    59581 gaatatgcag cataatattg gagattacaa agatcatcca aaatatattg caaagagtat
    59641 aaataagatt gaccagatga gccacttatt ggaagaagta ctggagtctt ctaaattcca
    59701 agagtggaca gagtgtcgtg agactttgac tgttaagcca gttttagtag atattttatc
    59761 acgttatcaa gaattagctc attcaatagg tgttacaatt gaaaatcaat tgacagatgc
    59821 taccagggtc gtcatgagtc ttagggcatt ggataaggtt ttgacaaacc tgattagtaa
    59881 tgcaattaaa tattcagata aaaatgggcg cgtaatcata tccgagcaag atggctatct
    59941 ctctatcaaa aatacatgtg cgcctctaag tgaccaagaa ctagaacatt tatttgatat
    60001 attctatcat tctcaaatcg tgacagataa ggatgaaagt tccggtttgg gtctttacat
    60061 tgtgaataat attttagaaa gctatcaaat ggactatagt tttctccctt atgaacacgg
    60121 tatggaattt aagattagct tgtagacaga ttagtttttt attaaagttc atatagggtt
    60181 aacataagtg tattattctt tatatagata aaaatataga taaaagaaag gatactaata
    60241 tggtattagc gattatttta gtaacattcc ttattcgatt gattttttta aagcgttcga
    60301 tagagaatga gaaacgaatc cttagcaatg gcgggaaaga atttggagtt gagaatacaa
    60361 aacgattaac gttggctcat attgtttttt atctctcttg cctcgttgaa gcaatggtgc
    60421 ataagacaat gtttgatggt atgagcatgg ttggtttagt cttgcttatt ttttctatgc
    60481 tgatgttgat gttggtgatt cacttgttgg gagatatttg gacagtgaag cttatgcttg
    60541 tcaataatca caaatatgta gatcatatct tgtttaggac agtaaaacat cctaattact
    60601 ttttaaatat tttacctgag ttgattggct tgaccttgtt gagtcatgcc tatatgactt
    60661 ttgttttagt ttttccagtt tatgcagtta ttttgtatcg acgaatagct gaagaggaaa
    60721 agctattaca tgaagttata atcccaaatg gaagcataaa gagataaata caaaattcga
    60781 tttatataca gttcatattg aagtgatata gtaaggttaa agaaaaaata tagaaggaaa
    60841 taaacatgtt tgcatcaaaa agcgaaagaa aagtacatta ttcaattcgt aaatttagta
    60901 ttggagtagc tagtgtagta gttgccagtc ttgttatggg aagtgtggtt catgcgacag
    60961 agaacgaggg aagtacccaa gcagccactt cttctaatat ggcaaagaca gaacatagga
    61021 aagctgctaa acaagtcgtc gatgaatata tagaaaaaat gttgagggag attcaattag
    61081 atagaagaaa acatacccaa aatttcgcct tcaacatgaa gttgagcgca attaaaacgg
    61141 agtatttgta tggattaaaa gagaagtcgg aagctgagtt gccgtcagaa gtaaaagcaa
    61201 agttagacgc agcttttgag cagtttaaaa aagatacatt gaaactagga gaaaaggtag
    61261 cagaagctga gaagaaggtt gcagaagctg agaaaaaagc caaggctcaa aaagaagaag
    61321 atcgccgtaa ctacccaacc attacttaca aaacgcttga ccttgaaatt gctgagtccg
    61381 atgtggaagt taaaaaagcg gagcttgaac tattgaaaga ggaagctaaa actcgaaaca
    61441 aggacacaat taaccaagca aaagcgaaag ttgagagtaa acaagctgag gctacaaggt
    61501 taaaaaaaat caagacagat cgtgaacaag ctgagactac aaggttagaa aacatcaaga
    61561 cagatcgtaa aaaagcagaa gaagaagcta aagttaaagc taaaccaaag aagcggacaa
    61621 aacgaggagc tcttggagag ccagcaacac ctgataaaaa agaaaatgat gcgaagtctt
    61681 cagattctag cgtaggtgaa gaaactcttc caagcccatc cctgaaacca ggaaaaaagg
    61741 tagcagaagc tgagaagaag gttgaagaag ctgagaaaaa agccaaggat caaaaagaag
    61801 aagatcgccg taattaccca accattactt acaaaacgct tgaacttgac attgctgagt
    61861 ccgatgtgga agttaaaaaa gcggagcttg aactagtaaa agaggaagct aaggaatctc
    61921 gagacaagga aaaaattaag caagcaaaag cggaagttga gagtaaaaaa gctgaggcta
    61981 caaggttaga aaaaatcaag acagatcgta aaaaagcaga agaagaagaa gctaaacgaa
    62041 aagcagcaga agaagataaa gttaaagaaa aaccagctga acaaccacaa ccagcgccgg
    62101 ctcctcaacc agaaaaacca actgaagagc ctgagaatcc agctccagct ccaaaaccag
    62161 agaagccagc tgaacaacca aaagcagaaa aaccagctga tcaacaagct gaagaagact
    62221 atgctcgtag atcagaagaa gaatataatc gcttgactca acagcaaccg ccaaaaattg
    62281 aaaaaccagc tccagcacca caaccagagc aaccagcaca accatctact ccaaaaacag
    62341 gctggaaaca agaaaacggt atgtggtact tctacaatac tgatggttca atggcgacag
    62401 gatggctcca aaacaatggc tcatggtact acctcaacag caatggcgct atggcgacag
    62461 gatggctcca aaacaatggt tcatggtact atctaaacgc taatggttca atggcaacag
    62521 gatggctcca aaacaatggt tcatggtact acctaaacgc taatggttca atggcgacag
    62581 gatggctcca atacaatggt tcatggtact acctcaacgc taatggtgat atggcgacag
    62641 gatggttcca atacaatggt tcatggtact acctcaacgc taatggtgat atggcgacag
    62701 gatggctcca atacaatggt tcatggtact acctcaacaa caatggtgct atggtaacag
    62761 gatggctcca aaacaatggc tcatggtact acctcaacgc taatggtgat atggcgacag
    62821 attgggtgaa agatggagat acctggtact atcttgaagc atcaggtgct atgaaagcaa
    62881 gccaatggtt caaagtatca gataaatggt actatgtcaa tggctcaggt gcccttgcag
    62941 tcaacacaac tgtagatagc tatagagtca ataccaatgg tgaatgggta aactaaacct
    63001 aatataacta gttaatactg acttcctgta agaactcttt aaagtattcc ctacaaatac
    63061 catatccttt cagtagataa tatacccttg taggaagttt agattaaaaa ataactctgt
    63121 aatctctagc cggatttata gcgctagaga ctacggagtt tttttgatga ggaaagaatg
    63181 gcggcattca agaggctctt taagagagtt acgggtttta aactattaag ccttctccaa
    63241 ttgcaagagg gcttcaatct ctgccagggt gctagcttgc gaaatggctc cacggagttt
    63301 ggcagcgcca gatgttccac ggagatagtg aggagcgagg ccgcggaatt cacgaactgc
    63361 gacgttttct cctttgaggt caatcaatcg tttcaagtgt tcgtaggcga tcttcatctt
    63421 gtcttcaaag gtcaaatcag gtaggatttc tcctgtttca aagtaatggt tgatttggtt
    63481 gaagaggtaa ggatttccca tggcagctcg gccaatcatg actgcgtcag caccaacttc
    63541 ttcgatgcgt tgcttggctt cttggacagt acggatatca ccgttggcga tgaatggaat
    63601 cttggttaga gcttgggcaa ccttgtaaag ggtctcaagg tctgcgtggc cagtatacat
    63661 ttgttcacgg gtacggccat gcatggcgag ggcagaaaca cctgcagctt cagcagcgag
    63721 ggcattttct actgccagag atgggtccgc ccagccggta cgcattttga cagtaagtgg
    63781 gatatcaagg acagactgga ccttgttgat gatggagtaa atcttgtctg gatccttgag
    63841 ccacatagca ccagcttcgt tcttcacgat tttgttgaca gggcagccca tgttgatatc
    63901 gacgatatcg gtcttggtgt tttcttggat aaattctgct gcgcgtgcta ggctgtcttc
    63961 atcgctacca aaaagttgga tagagacagg gttttcgccc tcatcgatat gaagcatgtg
    64021 cagggttttt tcgttgttgt attggattcc cttgtcagag accatttcca ttacaacgag
    64081 tccagctccg agctcttttg cgatggtacg aaaggctgag ttggtcacgc cagccatagg
    64141 cgctaaaacg gtacgattgg gaatctcaac attgccaatc ataaaaggtg tattaagatt
    64201 tgtcacgaat gagttcctcc aggtcctttt catcaaagtt gtaagtagtt tggcagaatt
    64261 gacaagtgat ttctaccccg tggtcttcct ctttcatttc ctgtaagtct gagcttggaa
    64321 ggctggcaag agcgttcata aagcgttcat ggctacagtc acattggaaa cggatttctt
    64381 cttcagaaag acgcttgtag gcttcgtccc cgtagatagc cttgaggagg gcttcgatat
    64441 ggtcgtcgct ttcgagaaga gtagagatag ctggcatttc ttggatgcgt ttttcaaagc
    64501 gagcaatctc ttctttcttg gctcctggca agacttgaac taggaaacca cctgcaacct
    64561 tgaccttgtc ttcctcgtcc aaaaggacat tgaggccgac cgctgaaggc gtttgttggc
    64621 tttcagtaag gtaaaaggca aggtcttcac cgatttctcc agagatgagg ggagttatag
    64681 agttgtaagg atttccagta ccgtagtctg tgataacgag gaattgacca tttccaacaa
    64741 aaggtccgac taggacttca ccagtcgcag tctttttgat gtcaacacca ggattttgaa
    64801 catagccttt gacgttcccc ttggtatcag cgacggtgat aatagcacct agagagctag
    64861 agcccaacac cttaactgta agtttggtat ttcctttttc attggctgcg agaatctggc
    64921 tggcgataag agttcgacca agcgctacag ttgagctagc ttgggtttga tgtttttctt
    64981 gagcagtgcg gacggtttcc gtgctatcaa ggacaaaagc acgaaaggct ccgctttctg
    65041 atatagtttt aataatttta tccatagcta ctattttagc ataaaaatgc ccaaaggggg
    65101 agccgtgtgt ttactgattt tcaggataat ggaccaggaa atcagcatga aaataaaaag
    65161 agaaacagat tattttagca tttgtaagat ttatgctatg cttaaggtag aaaatgaaag
    65221 gggtaacaaa tgtatttagg agatttgatg gagaaagccg agtgtggtca attttcaatc
    65281 ctttcctttc tattacaaga gtctcagacg accgtcaagg ctgtaatgga agaaacagga
    65341 ttttcaaaag caaccctaac caaatatgtc accctgctca atgacaaggc tttggatagt
    65401 ggcttagagc tgactattca ctcagaagat gaaaatctgc gtctgtctat cggtgcagct
    65461 accaagggga gagatattcg gagcttgttt ttggagagtg ctgttaaata ccagattttg
    65521 gtttatcttc tctaccacca acagttttta gcccatcagc tggctcaaga attggtgatt
    65581 agcgaggcta cgcttggtcg tcacttggct ggtttaaatc agattttgtc agaatttgat
    65641 ttatccatcc aaaatggacg ttggcgaggt ccagagcatc agattcgcta tttctatttc
    65701 tgtcttttcc gaaaggtctg gtcgagtcag gaatgggaag gtcacatgca gaaaccagag
    65761 agaaaacagg agattgccaa tttagaggaa atctgcggtg caagtttgtc tgtggggcag
    65821 aaattggact tggttctctg ggctcacatc agtcaacaac gtcttcgggt caatgcttgt
    65881 cagtttcaag tcatagaaga gaaaatgcga gggtattttg acaatatctt ttatcttcgt
    65941 ttgctgagaa aggttccgtc cttttttgct gggcaacata ttccactagg agttgaggat
    66001 ggtgagatga tgatattctt ctcttttctc ctatctcatc gcattcttcc tcttcatact
    66061 atggagtata ttcttggttt tggagggcag ttggcagatt tactgacgca attgattcaa
    66121 gaaatgaaga aggaggaact attgggggat tatacagagg accatgtcac ctatgaactc
    66181 agtcagcttt gtgctcaagt ctatctctat aagggctata ttttacagga tcgctacaag
    66241 taccagttag agaatcgtca tccatattta ctgatggaac atgattttaa agagacagca
    66301 gaggagattt ttcatgctct acctgctttt caacagggga cagatttaga taagaagatt
    66361 ctctgggaat ggctccagtt aatcgaatat atggctgaaa acggtggtca gcatatgcgg
    66421 attggtctgg atttgacatc tggttttctt gtcttttcaa ggatggcagc cattttgaaa
    66481 cggtatttgg aatacaatcg ttttattacc attgaagctt atgaccctag tcggcattat
    66541 gatttgctgg ttaccaataa cccgattcat aagaaggaac agacaccagt ctattattta
    66601 aaaaacgact tggatatgga agatttggca gggattcgtc agttattatt cacttaaaag
    66661 gcttggttaa tccaggtctt ttttgtgaaa ttcacacaat ctcctcacat ttttttaaaa
    66721 attaaaaaaa gttgataaac aagaaagcgc tttattttgt atactagtaa gtgtaaagag
    66781 gaaacacctc aagatcttta tcaggaggac agtacatgtc acaagaaaaa tacatcatgg
    66841 ccattgacca gggaactaca agttctcgtg ccatcatttt caacaaaaaa ggggaaaagg
    66901 ttagctcgag tcaaaaagag tttacccaga ttttccctca ggcaggttgg gttgagcaca
    66961 atgccaatga aatttggaac tctgttcagt cagttattgc gggtgctttc atcgaaagtg
    67021 gtgtcaagcc aaatcaaatc gaggcaatcg ggattaccaa ccaacgtgaa acaacggttg
    67081 tctgggataa gaaaacagga cttcctatct acaatgctat cgtttggcag tcacgccaga
    67141 cagcaccttt ggctgagcaa ctaaaaagcc aaggttatgt ggaaaaattc catgaaaaga
    67201 ctggtttgat tattgatgct tacttctctg ctaccaaggt tcgttggatt ttggatcatg
    67261 tagaaggcgc tcaagagcga gcagaaaaag gggaattgct ctttggtact atcgatactt
    67321 ggttggtttg gaaattgact gacggtgcgg ctcacgtgac tgactactca aatgcagctc
    67381 gtaccatgct ttataacatt aaagaactca aatgggatga tgagattttg gaaatcctta
    67441 acattccgaa ggctatactt ccagaagttc gttctaactc cgaaatctac ggcaagacag
    67501 ctccattcca tttctacggt ggagaggtgc caatctcagg tatggctggg gaccaacaag
    67561 cagccctctt tggacagttg gcttttgagc caggtatggt taagaatact tatggaacag
    67621 gctctttcat catcatgaat actggggaag agatgcagtt gtctgaaaac aacctcttga
    67681 caaccattgg ttacggaatc aacggtaagg tttattatgc cttggaaggt tctatcttca
    67741 tcgcaggaag tgctattcag tggcttcgtg acggtcttcg catggttgaa aattcaccag
    67801 aatctgaaaa atacgctcgt gattctcaca acaacgatga agtttatgtc gttccagcct
    67861 ttacaggtct aggcgctcca tactggaacc aaaatgctcg tggttccgtc tttggtttga
    67921 ctcgtggaac aagcaaagaa gactttatca aggcgacttt gcaatctatt gcttatcaag
    67981 tgcgtgacat catcgacacc atgcaagtgg atactcagac cgccattcaa gtattgaagg
    68041 tggatggtgg tgcagccatg aacaacttcc tcatgcagtt ccaggcggat attttaggca
    68101 ttgatattgc acgtgctaaa aacctggaaa caacagctct aggagcggcc ttcctagcag
    68161 gtttgtcagt agggtactgg aaagacttgg acgagttgaa actcttgaac gagacaggag
    68221 aactctttga gccatctatg aacgaatctc gcaaggaaca actctacaag ggctggaaga
    68281 aggctgtgaa agcaactcaa gtctttgcgg aagtagacga ctaatactgg cagaataaag
    68341 cgatttattt agaaagtgtg taaatatgga attttcaaag aaaacacgtg aattgtcaat
    68401 taaaaaaatg caggaacgca ccctggacct cttgattatc ggtggaggaa tcacaggagc
    68461 tggtgtagcc ttgcaggcgg cagctagcgg tcttgagact ggtttgattg aaatgcaaga
    68521 ctttgcagaa ggaacatcta gtcgttcaac aaaattggtt cacggaggtc ttcgctacct
    68581 caaacaattt gacgtagagg tggtctcaga tacggtttct gaacgtgcag tggttcaaca
    68641 aatcgctcca cacattccaa aaccagatcc aatgctctta ccagtttacg atgaagatgg
    68701 agcaaccttt agcctcttcc gtcttaaagt agccatggac ttgtacgacc ttttagcagg
    68761 tgtgagcaac acaccaactg cgaacaaggt tttgagcaag gatcaagtct tggaacgcca
    68821 gccaaacttg aagaaggaag gcttggtagg aggtggagtg tatcttgact tccgtaacaa
    68881 cgatgcgcgt ctcgtgattg aaaacatcaa acgtgccaac caagacggtg ccctcattgc
    68941 caaccacgtg aaggcagaag gcttcctctt tgacgaaagt ggcaagatta caggtgttgt
    69001 agctcgtgat ctcttgacag accaagtatt tgaaatcaag gcccgtctgg ttattaatac
    69061 aacaggtcct tggagtgata aagtacgtaa tttgtctaat aagggaacgc aattctcaca
    69121 aatgcgccca actaagggag ttcacttggt agtggattca agcaaaatca aggtttcaca
    69181 gccagtttac tttgacacag gtttgggtga cggtcgtatg gtctttgttc tcccacgtga
    69241 aaacaagact tactttggta caactgatac agactacaca ggtgatttgg agcatccaaa
    69301 agtaactcaa gaagatgtag attatctact tggcattgtc aacaaccgct ttccagaatc
    69361 caacatcacc attgatgata tcgaaagcag ctgggcaggt cttcgtccat tgattgcagg
    69421 gaacagtgcc tctgactata atggtggaaa taacggtacc atcagtgatg aaagctttga
    69481 caacttgatt gcgactgttg aatcttatct ctccaaagaa aaaacacgtg aagatgttga
    69541 gtctgctgtc agcaagcttg aaagtagcac atctgagaaa tatttggatc catctgcagt
    69601 ttctcgtggg tctagcttgg accgtgatga caatggtctt ttgactcttg ctggtggtaa
    69661 aatcacagac taccgtaaga tggctgaagg agctatggag cgcgtggttg acatcctcaa
    69721 agcagaattt gaccgtagct ttaaattgat caattctaaa acttaccctg tttcaggtgg
    69781 agaattgaac ccagcaaatg tggattcaga aatcgaagcc tttgcgcaac ttggagtttc
    69841 acgtggtttg gatagcaagg aagctcatta cctagcaaat ctttatggtt caaatgcacc
    69901 gaaggtcttt gcacttgctc acagcttgga acaagcgcca ggtcttagct tagcagacac
    69961 cttgtctctt cactatgcaa tgcgcaatga gttgactctt agcccagttg acttccttct
    70021 tcgtcgtacc aatcacatgc tctttatgcg tgatagcttg gatagtatcg ttgagccagt
    70081 tttggatgaa atgggacgat tctatgactg gacagaagaa gaaaaagcaa cttaccgtgc
    70141 tgatgtaaaa gcagctcttg ctcaaaacga cttagcagaa ttaaaaaatt aagaaaaaat
    70201 aaaagaggtg gagggtagca atccttgtcg cccgcccctt ttttaatgga gacagaaaaa
    70261 tgatgagtga attatttgga gaatttttag ggactttaat cctgattctt ctaggaaatg
    70321 gtgttgttgc aggtgtggtt cttccaaaaa ccaagagcaa cagtgcaggt tggattgtga
    70381 ttactatggg ttgggggatt gcagttgcgg ttgcagtatt tgtatctggc aagctcagtc
    70441 cagctcattt aaacccagct gtgaccatcg gtgtggcctt aaaaggtggt ttgccttggg
    70501 cttccgtttt gccttatatc ttagcccagt tcgcaggggc catgctgggt cagattttgg
    70561 tttggttgca attcaaaccg cattatgagg tagaagaaaa tgcaggcaat atcctggcaa
    70621 ccttcagtac tggaccagcc atcaaggata ctgtatcaaa cttgattagc gaaatccttg
    70681 gaacctttgt tttggtgttg acaatctttg ctttgggtct ttacgatttt caggcaggta
    70741 tcggaacctt tgcagtggga actttgattg tcggtatcgg tctatcacta ggtgggacaa
    70801 caggttatgc cttgaaccca gctcgtgacc ttggatctcg tatcatgcac agcatcttgc
    70861 caattccaaa caagggagac ggagactggt cttacgcttg gattcctgtt gtaggccctg
    70921 ttatcggagc agccttggca gtgcttgtat tctcactttt ctagtttata ctcttcgaaa
    70981 atcaaattca aaccacgtca gcgtcgcctt accgtactca agtacagctt gcggctagct
    71041 tcctagtttg ctctttgatt ttcattgagt attagaaaac aattattttg atagagcttg
    71101 ggcaagagcc caatttcagc aaaaaatgaa gtaaatcttc tcataataaa acgcatcata
    71161 tcaagcacga aaattccacg aggtcaacta cagtcagaaa gctgaacaac aagccaaaac
    71221 gcccaaaaaa ggcggcaaaa agcaagcacc tgcaagcaac gtgccgaaat ggtcaaatcc
    71281 tgattatgtc aacgaattag acccaaaaat cgttgatatg ctagtagaat ttcacaagtc
    71341 acaaggcact ttggaaactc ccgaggcgca agcagaaatc gcccaaaaac gtgaagaaat
    71401 cgagcaaagg agagctgagc ttgagggtaa aaaacaagag cttttgaacc gcttgaacaa
    71461 atagagtttc gcaagtatta tgcttacaaa ttacttgagc aattaactaa aatataaacc
    71521 ctgcctttat atctaggcag ggtttatatt ttagaaattc acgtaggttg ttacggtttt
    71581 tacataccca gtatagtttg agtttctata gtattcagtg ataaacttcc attttctttg
    71641 agcaacatgg atataagtac ttgttatgta gtatggatat gggctttgtg aatccaagta
    71701 agactgataa gcttgtatac caaaatatgc tccaccaatt attgcacccc atggaccccc
    71761 caataaagca cctatcctac caatcatata actgattcca gcaccagtca tgaagttagc
    71821 gaatgtgtta gcttgtttat tcccatgtat tgtgttgacg taattccaaa cattaggatc
    71881 gtatgatcta aaagatatat ttaggtcgat ttcattcttt tgataagcca tataaaatgc
    71941 cccattgata tagacgccgt cagcacgtcg ttcaatagtg tctacacttc catctggatt
    72001 gacaacctca agaacttcat cgcttaaaat atttacttgc gtatctccga accgcactga
    72061 tgagccattc tcaaactgag cctcaccaga tacaacttta gagtttgccg ataagctatc
    72121 atcagcaaaa acaaacaagc gacggggaaa tgctagacat acagaaaaca gacataacta
    72181 gcaaacacat gcatttaaac atcttagaca taacggaaac tcctttgtat ttttgatttt
    72241 tttcaacttt tattatacaa taaaaccaaa taaaaagaaa gcggtaacaa tatgcttaat
    72301 gcgaaaattt tttatatatt tttatgtttg atcgttatcg aaactacagg cttgttgttg
    72361 ttgaaaagag gtctcgaaat gggttattta gacacagaag ctattatcct cgcagttttt
    72421 tcatttgctt tttacaacct atgttcattc gcttgggtct gctctacaat aaaaaacaat
    72481 aaaaaataaa tagacgtatt ttcaaaaaaa aaaaaatgca tatttatctt agcaaaacga
    72541 cgatttaaat cgtcgttttt ttgtagtacg acgggcatgt cgtatatctg aggtgtaagt
    72601 cctcggtggg cacctgctac cggtgaaccc aatagcgatt cccaagcctg actatcgtga
    72661 ggtagcggat taaaacggtc tggggataga ccgttttaag tctgacgcag gaaataagaa
    72721 tcgtcagagg aagagatagc gaaatcgtgg ctctacgaac aggaacgtga tagcaaggcg
    72781 tatatagcgg ataaggaggc ttcaaactct aaagtccaaa aaggtagtcg taacctatat
    72841 gtgtaaatca cgagagtaat tgaattcgga ctaaggtttg tgtgaaaaag ataaatcttt
    72901 ctagagtcta aagactctgc gtcagatttc ctattttcac tgtaaccttt taacgtcctc
    72961 atatcttgta taaacgagga aagatgtacg acttatcccg tgaggtttca tgagcgctga
    73021 aagcgtagta acaacgaatc atgagaagtc agccgagccc atagtagtga ggaaacttcc
    73081 gtaatggaag tggagcgaag gggtgaatac tcaaacagtc tggggagaga ctgtttgagg
    73141 tctgtcgcta gaaagagaaa acgacagatc gaagtaatcc tacttcactt gtgtctgtaa
    73201 aatgagtggt ctgatagaac tggactttga cacgtaatga ctagatgaag gttcaccaat
    73261 ataagatgtc cctcaggcac caaaacaaga aaggaatacg cacatgtcaa aattgctaga
    73321 taagatatta tcacgcgaaa atatgctgga agcctacaat caagtaaaat ccaataaagg
    73381 ctcagctggg attgatggaa tgactatcga agagatggat aattatctca gacaaaactg
    73441 gcgcttgact aaggaactga taaaacagag aaaatataag cctcaaccag ttcttagagt
    73501 tgagattact aaaccaaacg gaggtatccg tcaactagga attccaacag ttatggatag
    73561 aatgattcaa caggccattg tccaagttat tagccccatt tgtgaacccc atttctcaga
    73621 tacgagttat ggcttcagac caaataggtc atgtgaaaaa gccatcatga agttcttaga
    73681 gtacttaaat gacggctatg agtggatagt ggatatagac ctagagaaat ttttcgatac
    73741 ggttcctcaa gatagattga tgtccttggt acataacatt atcgaagacg gagatacgga
    73801 atccctgatt cgtaagtatc ttcattcagg tgttatcatt aatggtcagc gtcataaaac
    73861 gctagttggc acgccacagg gaggaaattt atctcctctc ttatccaatg tcatgcttaa
    73921 tgaattggac aaggaattag aaaagagggg acttcgattt gtgcgctacg cagatgattg
    73981 tgtgattacg gtcggaagcg aggcagccgc taagcgtgtg atgtattcag ccagtcgttt
    74041 tattgagaag cgactaggtt tgaaagtaaa tatgaccaag gctaagatta ccagaccaag
    74101 agagctgaaa tacttaggtt ttgggttctg gaaatcatca gatggttgga aaagtcgtcc
    74161 ccatcaagat agtgttcgga gatttaagct taaattgaag aaactaacac agaggaaatg
    74221 gagtatagac ttaacaagac gtattgagca actgaatttg tctattcgag gatggataaa
    74281 ctatttctcg ctgggaaata tgaagcgcat agtcgctagc atagatgagc gcttgcgtac
    74341 tcgcctacga gtgattatct ggaagcaatg gaagaagaaa tcgagacgac tatggggatt
    74401 gcttaagtta ggagttccta aatggatagc agataaggta tctggctggg gcgaccatta
    74461 tcaattagta gctcagaagt cggtacttaa acgtgctata tcaaaaccag tccttgaaaa
    74521 acgtggactg gtttcgtgtt tggattatta ccttgaacga catgcgttaa aagttagttg
    74581 aaccgccgta tgccgaacgg catgtacggt ggtgtgagag gggctagaga ttatccccta
    74641 ctcgattaac tcccctgaaa tttattttaa ttatgcaaat ttcacgtatt tttgatgctg
    74701 agacgacgat ctgggaactt ttcagatatt tttttgacta tctaaaatct atcattagaa
    74761 aagcttagag cgccaaagga tttgagcgtt tttctgattt ttaagacttt ttcccagtct
    74821 ctttttcgat tgaagatgta attattctac taactaacta acttcttagt actagccaac
    74881 aacgataatc ataattcctc ctaaaattag gaataataaa ggcaatagtt tttgtttttt
    74941 catgtaaaaa acctcacttt tgttttctgc tattttatgc taaaatatta aaaatcaaat
    75001 ttaattccaa agtttgtaac taaaggggga gcgctacatg tctaattcat ttgtcaagtt
    75061 gttagtctct caattatttg caaatttagc agatattttc tttagagtaa caatcattgc
    75121 taacatatac attatttcaa aatcagtaat tgccacatca ctagttccta tcttaatagg
    75181 aatatcctct tttgttgcga gtcttttagt tccgttggtt actaaaaggt tagcgctaaa
    75241 tagggtttta tctttatctc aatttggaaa gactatatta ttggcgatac tggtaggaat
    75301 gtttaccgta atgcaatccg tagcgccttt ggtgacctat ctatttgttg ttgcaatttc
    75361 catactagat ggttttgcag cacccgtttc ctatgctatt gtgccacgct atgcgaccga
    75421 tttgggtaag gctaattcag ccttatcaat gactggtgaa gctgttcaat tgataggttg
    75481 gggattaggt ggactcttat ttgcaacaat tggtctgtta cctaccacgt ttatcatttt
    75541 agtcttgtat atcatttcta gctttctgat gttatttctt cctaacgctg aagtggaggt
    75601 gttagagtca gaaactaatc ttgaaatttt gctcaaaggt tggaagttag ttgctagaaa
    75661 tcctagatta agactttttg tatcagcaaa tttattggaa attttttcaa atacgatttg
    75721 ggtttcttcc attatacttg tttttgtaac ggagttatta aataaaacgg aaagttactg
    75781 gggatattct aatacagcat actctattgg tattataatt agtggcttaa ttgcttttag
    75841 gctatctgaa aagttccttg ctgctaaatg ggaaagtatt ctttttcctc ttgtagctat
    75901 ggcaatagtg acactgacta ttctatattt tccaaacgca cagatgtttt tattattttc
    75961 agctttagtt ggtatgttat cgcaactaaa agaagttcct gaaagtgtat ttcttcagga
    76021 aacagtagag gaaaatcatt tagttaatgt ctattccgtt cttgaagtga tttctacatt
    76081 agcattttca gtatttgttt tgctaatgag ctatattact gagagttttg gtattagcat
    76141 cagtttttgg ctatcagcca tttgtctgat gatagaagct attttaattt atatcagacg
    76201 agattatttt aaatgagaga gtggttaaaa agtctttaaa aatcagaaaa gcgcatagta
    76261 tcaggtgttg aaaaaacttg atattgtgtg ttttattatg ggaagattta cttcattgtc
    76321 tcctgaaatg gagttttgaa gcaggatcac tctatttgaa aatatacata gaaaaactgt
    76381 ataatcctta aaataagctg aaatctattg gaaacatacg gtaaacaatt gaaaagatac
    76441 tatataaagt ggtacaatgg tagaaaaata agctagtaag aatcactctt attttagcga
    76501 aaaattacag aaatgaatgg tttttcttga tgaaacagag aaaagaattg tacctctttc
    76561 ttggtcggac agccttgtat tttcttatct ttctagggct gctttacttc tttagctatc
    76621 ttggtcaggg tcaaggaagc tttatctata atgaatttta acttgaagga gaatccctat
    76681 tgtgtcaaat aaaccaatag cagatatgat tgaaaccatt gagcattttg ctcagacaca
    76741 gcctagctat cctgtctata atgttttggg gcaggaacac acttatggcg atttaaaggc
    76801 tgattcggat agtttggctg cagtcattga ccaactaggc ttgcctgaga agtctcctgt
    76861 ggttgttttt ggtggccaag aatatgaaat gttggcaacc tttgtagcgc tgactaagtc
    76921 aggtcatgcc tacattccaa ttgatagcca ttcggccttg gagcgagttt cagctatttt
    76981 agaagtagca gagccaagct tgattattgc catttcagcc tttcccttgg agcaggtttc
    77041 tacaccaatg ataaatctag ctcaggttca agaagccttt gcccaaggga acaactatga
    77101 aatcacgcat ccagtcaagg gagatgataa ttactacatt atctttactt ctggtacgac
    77161 tggtaagcct aagggagtgc agatttcaca tgataatctc ctcagcttta caaactggat
    77221 gattacggat aaggaatttg cgacaccgag tcgtccgcaa atgctggcac agccacctta
    77281 ttcttttgac ttgtctgtca tgtattgggc accgaccttg gcacttggtg gtacgctttt
    77341 cactcttcct tcagtcatca ctcaggactt taagcaactc tttgcggcta tcttttcatt
    77401 gccaatcgct atctggacat caacaccatc ctttgcagat atggccatgt tgtctgaata
    77461 cttcaacagt gagaaaatgt ctggaatcac gcatttctac tttgatggtg aagaattgac
    77521 ggtcaaaaca gctcaaaaac tgcgcgagcg tttcccaaat gcccgtatca tcaatgctta
    77581 cggcccaaca gaagcgacag tagctctgtc agcagttgcc gtgacagacg agatgttagc
    77641 gactctcaaa cgcctaccaa tcggctatac caaggctgat tctccaacct ttatcattga
    77701 cgaggaagga aataaactgc caaatggtga gcagggagaa atcattgttt ctgggccagc
    77761 tgtttcaaaa ggttatatga aaaatcctga aaaaacagca gaagccttct ttgagtttga
    77821 aggtctgcca gcctatcaca caggcgatgt gggaaccatg acagatgagg gcttgcttct
    77881 ctacggcgga cgcatggact tccagattaa gtttaacggt taccgcattg agttagaaga
    77941 tgtctctcaa aacctcaaca agtctcgctt tatcgaatct gctgtcgcag taccgcgcta
    78001 taacaaggac cacaaggtac aaaatctatt ggcttatgtc atcttaaaag acggtgttcg
    78061 tgagcagttt gagcgagata tcgatattac caaggccatc aaggaagacc tgacagacat
    78121 catgatgtcc tacatgatgc catctaaatt cctttaccga gacagtttgc cactaactcc
    78181 aaatggaaag attgacatca aaggattgat taacgaggtg aataagagat gatggagttt
    78241 tttcaacagc ttcctcattt agagccatat ggcaatcctc agtattttgt ttatgtgatt
    78301 gctgcaacct tgcccatctt tataggcctc tttttcaaga aacgctttgc ctggtatgaa
    78361 gtgttggtaa gtctcttctt tattgtcacc atgttggtgg gtggaaagac caatcaacta
    78421 gctgccttgg gtatttacct ttgctgggaa atattgctcc tgcttttcta caagcattat
    78481 cgaaaaagca aggatggcaa gtgggtcttc tacttagtta gttttctgtc cctacttccg
    78541 attatctttg tcaaggtgca accagctatc aatggaacgc agtctttgct tgggttcttg
    78601 ggaatttctt acctgacctt tcgttcggtt gggattatca tcgagctgag agatggagtg
    78661 attaaggatt ttaccctctg ggaattcctc cgtttccttc tcttcatgcc aactttctcg
    78721 agtggtccaa tcgatcgctt taagcgattt aatgaaaatt atcaggctat tcctgagcga
    78781 gatgagttga tggatatgct ggatgaatct gtccgctata tcatgtgggg ctttttgtat
    78841 aagtttatcc tagctcatgt tttaggagag accttactac ctcctctgaa gaatttagcc
    78901 ttgcagtcag gtggcttctt taatctctat gccttggcag ttatgtatac ttttggtctg
    78961 gagctcttct ttgactttgc aggttattct atgtttgctt tggccatctc aaacttgatg
    79021 ggaatccgta gccctatcaa ctttaacaag ccctttttat caagggattt aaaggagttt
    79081 tggaatcgct ggcatatgag tctgtccttc tggttccgtg actttgtctt tatgcgaatg
    79141 gtgatggtgt taaccagaaa gaaagtcttt aaaaatcgta atgtaacctc aagcatggcc
    79201 tacattgtaa atatgctgat tatgggattt tggcatggtg tgacctggta ctatatcgcc
    79261 tatggactct ttcatggact aggcttggtc atcaatgatg cctgggttcg caagaaaaaa
    79321 acgctcaata aggaacggaa aaaagcaggg aaggctgccc tacctgagaa tcgctggatt
    79381 cagttgcttg gcatggttgt cactttccat gttgtcatgt tgtcattctt aatcttttct
    79441 ggattcttga ataatctatg gtttaaaaaa taaaaggaaa taaaatatgg atatcaaatc
    79501 agaagttatt gaaattattg atgagttgtt tatggaagat gtttctgaca tgatggatga
    79561 agatcttttt gatgcaggtg tcttggatag tatgggaacg gttgagttga ttgtggagat
    79621 tgagaaccgt tttgacattc gtgtccctgt aacagagttt ggtcgtgacg actggaatac
    79681 agctaataaa atcatagctg gtattgtgga gctacaaaat gcttaaacgc ttatggatga
    79741 tcttcggacc ggtcttgatc gctggtttgt tggtttttct gctcattttc ttttatccta
    79801 ctgagatgca tcataatcta ggagctgaaa agcgttcagc agtggctact actatcgata
    79861 gttttaagga gcgaagtcaa aaagtcagag cactatctga tccaaatgtg cgttttgttc
    79921 ccttctttgg ctctagtgaa tggcttcgtt ttgacggtgc tcatcctgcg gtattagctg
    79981 agaaatacaa tcgttcctac cgtccttatc ttttaggaca ggggggagct gcatcgctta
    80041 accaatattt tggaatgcaa cagatgttac cacagctgga gaataaacaa gttgtgtatg
    80101 ttatctcacc tcagtggttc agtaaaaatg gctatgatcc agcagccttc cagcagtatt
    80161 ttaatggaga ccagttgact agttttctga aacatcaatc tggggatcag gctagtcaat
    80221 atgcagcgac tcgcttactg caacagttcc caaacgtagc tatgaaggac ctggttcaga
    80281 agttggcaag taaagaagaa ttgtcgacag cagacaatga aatgattgaa ttattggctc
    80341 gttttaatga acgccaagcc tccttttttg gtcagttttc ggttagaggc tatgttaact
    80401 acgataagca tgtagctaag tatttaaaaa tcttgccaga ccagttttct tatcaagcaa
    80461 tagaagatgt tgtcaaagca gatgctgaaa aaaatacttc caataatgag atgggaatgg
    80521 aaaattattt ctataatgag cagatcaaga aggatttgaa gaaattaaag gattctcaga
    80581 aaagctttac ctatctcaag tcgccagagt ataatgactt gcagttggtt ttaacacagt
    80641 tttctaaatc taaggtaaac ccgattttta tcattccacc tgttaataaa aaatggatgg
    80701 actatgctgg tctacgagag gatatgtacc aacaaacggt gcagaagatt cgctaccagt
    80761 tagaaagtca aggttttacc aatatagcag atttttctaa ggacggtggg gagcctttct
    80821 ttatgaagga caccattcac cttggttggt tgggttggtt ggcttttgac aaggcagttg
    80881 atcctttcct atccaatccc acaccagctc cgacttacca tctgaatgag cgctttttca
    80941 gcaaagattg ggcgacttat gatggagatg tcaaagaatt tcaatagata atataatata
    81001 gaagagttca agaatgaaac tagttttcac gttttttctt gactcttttt ttgcttgtga
    81061 tataattaac tggtaaacaa aatgtcaaag aatagtattt ttctcttaaa aaagagaagt
    81121 ctaaaaggaa aggagtcaga tatgagacag ctagcaaagg atatcaatgc ttttttgaat
    81181 gaggtgattt tgcaggcgga aaatcagcat gaaatcctaa taggtcattg cactagcgag
    81241 gtggccctga ccaatactca ggagcatatc cttatgctct tgtcagagga atctttaaca
    81301 aattcagaat tggcccgtcg tctcaatgtc agtcaggcgg cagttaccaa ggccattaag
    81361 tctttggtca aggaagggat gttggaaaca tctaaagatt ctaaagatgc gcgtgtgatt
    81421 ttttatcagt tgactgactt ggctcgtcca atcgctgagg agcaccacca tcaccatgag
    81481 catacacttt taacctatga acaagtggcg actcagttta ctccaaatga acaaaaagtg
    81541 attcagcggt ttttgactgc tttagtagga gaaatcaaat aatgagatat attacggtag
    81601 aggatttgtc cttctattat gataaggagc ctgttcttga acatatcaat tatagtgttg
    81661 atagtgggga atttgttacc ttgactgggg aaaatggagc ggctaagacg acgctcatca
    81721 aggccagtct tggaattctg caaccacgca ttggaaaggt ggctatttca aagacaaata
    81781 cgcaaggtaa gaaattgaga atagcctatc ttcctcaaca aattgccagt tttaatgctg
    81841 gttttccaag tacggtctat gaatttgtca agtcgggtcg ctatccgaga aaaggctggt
    81901 tccgtcgttt gaatgctcat gatgaggagc atatcaaggc cagtctggac tcagttggca
    81961 tgtgggaaca tcgagacaaa cgcttggggt ctctatctgg gggacaaaag cagcgagcgg
    82021 tgattgcgcg tatgtttgct tctgaccctg atgtgtttat cctagacgag ccgacaacgg
    82081 ggatggatgc aggaagtaaa aatgaatttt acgaactcat gcaccacagc gcccatcatc
    82141 atggcaaggc tgttttgatg attacccatg accctgaaga agttaaggat tatgcggatc
    82201 gcaatattca tctagtccgt aaccaagact cgccatggcg ttgtttcaac gttcatgaga
    82261 atgggcagga ggtgggccat gcttagttta ttatcttatg actttataca acgcgccttt
    82321 ttggcggtta ttgctatgag tcttttctca ccggtattgg gaaccttcct catcttgcgt
    82381 cgtcagagtt tgatgagtga tacccttagc cacgtctcac tttcaggtgt agcctttggt
    82441 ctggttttgg ggatttctcc aactgtttct actattgcca ttgtcttgat tgcggcggtc
    82501 tttctggagt atctccgtac ggtttacaag agctttatgg aaatcgggac agctatcctc
    82561 atgtcaacag gtttggctgt ttctctgatt gtcatgagca agggtaaaag ctcgagttca
    82621 atgagtttgg accaatatct ctttggttcg atcgtgacta tcagtgaaga acaggtcatt
    82681 tccctctttg tcattgcggc ggttgttttg attttgacct ttctctttct tcgtcctatg
    82741 tatatcttaa cttttgacga agatacggcc tttgtggatg gcttgccagt tcgtaccatg
    82801 tccattcttt ttaacatggt gacaggggtg gctattgccc ttatgattcc tgcagcagga
    82861 gctcttctgg tatcgaccat tatggtcttg ccagctagta ttgccctgcg tctggggaaa
    82921 aactttaaat cggttatgct gcttgccagt gcgattggct ttttgggaat ggtagcagga
    82981 ctttacattt cctactatgc agaaacacct gcaagtgcaa gtattaccat tatttttgta
    83041 actgtcttta tactaatcag tttagtaaga cgttttatca aataggagac gaacgtgaaa
    83101 aaaattagct tattactagc cagtctatgt gccttgtttt tagtggcttg ttccaatcaa
    83161 aaacaggcag atggtaaact caatatcgtg acaacctttt accctgtcta tgaatttacc
    83221 aagcaagtcg caggagatac ggctaatgta gaactcctaa tcggtgctgg gacagaacct
    83281 catgaatacg aaccatctgc caaggcagtt gccaaaatcc aagatgcaga taccttcgtt
    83341 tatgaaaatg aaaacatgga aacatgggta cctaaattgc tagatacctt ggataagaaa
    83401 aaagtgaaaa ccatcaaggc gacaggcgat atgttgctct tgccaggtgg cgaggaagaa
    83461 gagggagacc atgaccatgg agaagaaggt catcaccatg agtttgaccc ccatgtttgg
    83521 ttatcaccag ttcgtgccat taaactagta gagcacatcc gcgacagctt gtcagcagat
    83581 tatcctgata aaaaagagac ctttgagaag aatgcagctg cctatatcga aaaattgcaa
    83641 gccttggata aggcttacgc agaaggcttg tctcaagcaa aacaaaagag ctttgtgact
    83701 caacacgcag cctttaacta tcttgccttg gactatggac tcaaacaagt cgcaatctca
    83761 ggactttctc cagatgcaga gccatcagct gctcgcttgg cagaattgac agagtatgtc
    83821 aagaaaaata aaatcgccta tatctatttt gaagaaaatg cctcacaagc ccttgctaac
    83881 acactttcaa aagaagcagg tgtcaaaact gatgtcctca atcctttaga aagtctgaca
    83941 gaagaggaca ccaaggctgg agaaaattac atctctatca tggagaaaaa cctcaaggct
    84001 ttgaaacaaa caacagacca agaaggccca gcgatcgagc ctgaaaaggc agaggatacc
    84061 aagacagtcc aaaatggtta cttcgaggat gcagctgtca aggaccgcac cttgagtgac
    84121 tatgcaggta actggcaatc agtttatcct ttccttgaag acggcacgtt tgaccaagtc
    84181 tttgactaca aggctaagtt gactggtaag atgacccagg ctgagtacaa ggcttactat
    84241 acaaaaggct atcagacaga tgtgactaag attaacatta ctgataatac tatggaattt
    84301 gttcaaggtg gacaaagcaa gaaatatact tacaagtatg tcggtaagaa aattttgact
    84361 tacaagaaag gcaatcgtgg cgtgcgtttc ctctttgaag ccacagatgc tgacgctgga
    84421 caattcaagt atgttcagtt tagtgaccac aatatcgccc cagttaaggc agaacatttc
    84481 catatcttct ttggaggcac aagccaagaa gccctctttg aagaaatgga caactggcca
    84541 acctactacc cagataacct atctggccaa gaaatcgctc aagaaatgtt ggcgcattga
    84601 tgagaaatcg actagttcat aagagctagt cggttttttg atactagatg gctaacttca
    84661 ttatagacct ttcagaacta agggaacctg aaaaaataaa taaaactctt gaaatatctg
    84721 ggcttatatg ctagaatgta gttagtgtat aaggttcatt agaacaccaa agcccctaac
    84781 tagtgccata gttaagggct tttttgacgt atcttagcga tttaacgggt gtttataggc
    84841 tagtcagtcg gtctacttct taccatctag ccatttgcag acgaaataca agataattcc
    84901 agctataaca tctgctataa tagtaagagc aagctctggt ataaggctca ttagtttcac
    84961 ctcctctcac gaaccgtaag gaacgtaatc ggtaaccgat gacaaaaata gtatatcaca
    85021 ttaaatttag atcatcaaca ttgcttaatg cttgaaatat taggacttat atgctaaaat
    85081 gtagttaatt gataaggttc attagaacac caaagcccct aactatggcc gtagttaagg
    85141 gcttttttga cgtatcttag cgatttaacg ggtgtttata ggctagtcag tcggtctact
    85201 ccttactatc tagccatctg cagacgaaat acaagataat tccagctata acatccgcta
    85261 taatagtaag agcgagctct atgataaggc tcattagttt cacctcctct cacgaaccca
    85321 taggaacgta atcggtaacc gatgacaaaa atagtatacc acaatacatt tagatcatca
    85381 aggtcactta attcttgaaa tatagggtct aggcgacaaa gtctttaaaa tcagaaaaac
    85441 gcataatatc aggtgtgcaa aaacttgata ctatgcgttt tattgtggga atatttgccc
    85501 catttctcct gaaattgagt ttttgtccag cctctgtttt tagggttgct aagaaaataa
    85561 tgtcatgtgg tgaatatttg taaatcagtc agcagacaga acgatactct tcgaaaatct
    85621 cttcacatca tgtcagcttc gtcttgccgt gtccatgggg gccttgactt catcagtttt
    85681 caaatctgta ctgtgagcaa gctgagacta gcttcctatt tgatttttat tgaatatcag
    85741 aaacccattc tccatcaaat aattcgactg cgtctaataa tttttggtct ggcaaggtgt
    85801 cagaaataaa ggttgtgtat ttggataggg gattaatttt aaaaaatcca gtcttgtaaa
    85861 atttagaact atcaatcagt aagatggttt catgggcttt gtcaataata ttcttttttg
    85921 aaatagcttg gctgagagaa gcttcataaa catattggtc atcaatacct cttgctgaac
    85981 aaaatgctaa atcgatatta aaatgatcta ataaagaatt ttccttatca tagttgacca
    86041 cggaacagga ttgatgtttg acctcgccag atgtgataaa gattttggag ctatctttaa
    86101 cagtttcaga tagggtttgt gcagtatgta aaccatttgt aaaaataatc aaattatcaa
    86161 gttcagaaag atagggacaa agttcgtaga cagtagtact agaatctaga tagatacaca
    86221 taccagaccg aataaagtct ttagcgagac tagcgattag tcttttttgc ctagtacttt
    86281 ctccttcccg tatttgatga gaaagttcaa ttgtgttcat agaggacagg gtcacgtatc
    86341 cgtgctttct tttgataaga ccttgatttt ctaagaaaat taaatcacga cgtaaggtac
    86401 ttgtgctgga gaaagtgatt tctgccagct cttttacggc aattcttttt ttctttttga
    86461 tgatttcaat caattcaagt acacgttcat cttttatcat aagctcctcc taatttatca
    86521 tttcaactat attatagcac aaattggagg aatgtgaatt atttttatga atattgggtt
    86581 aacatttgaa cattattcaa gtaagcgttc acatattgaa aaaataaaac gtggggatta
    86641 taataaagtt aatcaaggac gaagagagaa gaaaaatgga agcggtttta gcaatagatt
    86701 taggtgcgac ttctggaaga gcaatcgttg gttacctttc tgaaaataaa ctagtaatgg
    86761 aagaaataaa tcgcttttct aatctaccta ttagagtaaa agggcattta tcttgggatg
    86821 ttgactttct actagctaaa attcttgaaa gtatccgctt ggctaatact agttacaaga
    86881 ttttatctat cggtattgac acatggggag ttgattttgg actgattgat aatgaaggta
    86941 agctgttatc acaacctgtt cattatcgtg atgaaagaac aaagggagtg ttaaaggaaa
    87001 tatctgaaat gactgaatta gaaaaactgt attcagagac aggaaatcag attatggaga
    87061 taaatacctt gtttcaactc tttaaggcac gtcaagaatc tcctgactct ttctataaga
    87121 ccaataagat tcttttaatg ccagatttgt ttaattatct cttgacaggt aagtttgcta
    87181 cagaaaaaag cattgcttca acaactcaat tatttgatcc taggagtcaa aattggaatc
    87241 agaatatctt aaaactattt gaattggatt caactttact tcctgaaatt gtttcagagg
    87301 gaaatgtcct tggaaggata aaaaaggagt atggtttaag cgatattcct gttgtgaatg
    87361 tttgtagtca tgatacagca agtgcgattg tctcagtacc taagacagaa ggtagtttat
    87421 ttatttcatc aggtacttgg tctttggttg gagtggaact tacttcaccg attcttacta
    87481 ccgaatcctt cagttatgga tttacaaatg aagtcggtaa agatggagtg attacatttc
    87541 tgaagaattg tacagggttg tggatcatag aggaactaag acgttcattt gaacgaagag
    87601 ggaaagccta ttcttttgat gatattagga caatggtgga gaaagaaaaa gaaaatcttc
    87661 ctctgattga tactgaatca actgaatttg caacagaatc tgatatgcac aagactttga
    87721 cagaatatct agcttatcat catgaaacta gagagtggac agatggacaa ctatttaaga
    87781 ttgtttatga aagcctagct gaaacgtata ggaaagcgat agagttacta gaagaactaa
    87841 ctcataaggt ttataagagg atatatgtga ttggaggagg tgctagagcc agttacttta
    87901 accaaatgat tgctgataga actggtaaag aggttcttac aggtttgact gaggctacag
    87961 ctgtggggaa tattgttgtg cagctcatag ctatgggaca attaaaaggg atggaagagg
    88021 ctcaccatgt tattgaggag tttctacaat tagagagtta ttactcccaa aagaattaaa
    88081 aagattgaga gtttgtaaat ttgcctccct cccccttctt agcttttgtg caggaagggg
    88141 ggataattgg tgaattgaaa aatatttagt gttttgatat gaggaggaca aggatgtcag
    88201 atgtaaaaca agaattaatt aaatatggta agaagctagt agaaacagat ttgacgaaag
    88261 gaacaggtgg gaatctcagc gttttcgatc gtgaaaaaca attgatggca attaccccgt
    88321 cgggtattga tttctttgaa atcaaagaat ccgatattgt agtgatggat attaatggaa
    88381 atgttgtaga gggagaacgc ttgccatcta gcgaatggta tatgcatttg attcaatatc
    88441 aaactcgtga tgatatcgat gcaattatcc atgctcatac aacttatgca acagtattag
    88501 cttgtctcag agaaccactt ccagcgagtc attatatgat tgcagtggca gggaaagatg
    88561 ttcgggtagc tgagtatgca acatatggca cgaaagaatt ggctgtgaat gcagctaaag
    88621 caatggaagg tcgtagagca gttttactag cgaatcatgg aattttagca ggtgcacaaa
    88681 atttattgaa tgcatttaat attgttgaag aagttgaata ttgtgcaaaa atttattgtt
    88741 tagctaagaa ttttggagag ccagtagttc ttcctgatga ggagatggaa ttgatggcag
    88801 aaaaatttaa aacatacggt cagagaaaat agggaggata ttaatgttaa aacatatacc
    88861 gaaaaatatt tctccagatt tattgaagac tttaatggaa atgggacatg gagatgaaat
    88921 agtattagct gacgcgaatt atccttctgc ctcatgtgca aataagctaa ttcgttgtga
    88981 tggcgtaaat attccagaat tattagattc cattctgtat ttaatgccat tagatagtta
    89041 cgtcgatagt tcaattcagt ttatgaacgt tgtttcgggt gatgatattc ctaagatatg
    89101 gggtacctat agacagatga ttgaaggtca tggtacagat cttaaaacga ttacttatct
    89161 tagaagagaa gacttttatg aacgtagtaa gaaagcttat gctattgttg ctacaggaga
    89221 aacttcactt tatgctaata ttatccttaa gaaaggagta gttgttgaaa gagaaaatgt
    89281 ttaatagagg aattttagtt gccagtcatg gtgattttgc tagcggagct ctcatgaccg
    89341 cagaaatgtt tgttggtgag acaacaaatg atagagttag gacattaggt ttgatgcctg
    89401 gagagaatat tgtagagttt gagcattatt ttaaaaatca agtggatgaa ctgttagact
    89461 caaatcaaga ggttatcgtt ttgactgact tgattggagg aagtcctaat aatgtggctt
    89521 tgtcacggtt tttaaatttg gattcagttg atattgtaac agggtttaat attcctctcc
    89581 tagtggaatt aatatcaaat tatgattcaa aaatcaattt agaagaaatt gttcacaatg
    89641 ctcaaaatag tttgtttaat gttaaacaac aacttaacgt agaggaggaa gaagatttat
    89701 gtctatagag tttgttcgta ttgatgaccg tctggtacat ggtcaagttg tcactacgtg
    89761 gctaaaaaag tatgatattg agcaagttat cattgttaat gatcgcatct cagaagataa
    89821 aacacgacaa tctattttaa agatttctgc accagtaggt ttaaaaattg ttttctttag
    89881 tgtaaaacgg tttgtggaag ttttaaactc tgtgccaata aaaaagagaa caatgctgat
    89941 atatacaaat ccaaaagatg tgtatgattc tattgaagga aatttaaaat tggagtacct
    90001 caatgtagga cagatgagta aaacggagga aaatgaaaag gtaacgggag gtgtagctct
    90061 aggtgaagaa gacaaatatt attttaagaa aatagttgat aagggaacga gagttgaaat
    90121 tcaaatggtt cctaatgata aagttacaat gttggaaaaa tttttataaa aatagtttaa
    90181 ggaggtacag tatatgctat tcacacaagc attactggtg acattagttg ggattattgc
    90241 cactattgac tataatggac cgttatttat gatccaccgt ccgttagtta caagtgcaat
    90301 ggttggctta gtcttaggag atttcaccca aggtgttctt attggttcag ctcttgaatt
    90361 aacttggctc ggtgtaacag gtattggagg ttacactcca ccagatacta tttcaggtgc
    90421 gattattggt actgcatttg gtattttatc tggtcaagga gaaactgctg gtatcgctat
    90481 agcagttcca attgcagttg ctacccaaca gttggatgtt cttgcaaaaa ctttagatgt
    90541 ttattttgtg aaaaaagctg ataatgatgc taaaaacgga gattattcaa agatcggttt
    90601 ttatcattat tcaagtttgg ttttaatcac gttatttaaa attgtaccaa ttttcctagc
    90661 tattatgctt ggaggggaat atgtggcaga cttgtttgct aaggttccac caatcgttat
    90721 gcagggactt aactctgcag gtgctttact accttcaatt ggttttggta tgcttttaaa
    90781 tatgatgctc aagaaaaata tgtgggtatt cttgttgatt ggattcattt gttctgtgta
    90841 tggaggaatg tcaaccattg ggatctcact agttggtatt gcggtagcat acttctacga
    90901 tatgattgga agtaaaccac aagaaacaac ttcaagtagt gatgttgagg aggatcttga
    90961 tctatgatga ataataaagt aactaaagtt gaacttaaaa aagttttcaa acgaagtttt
    91021 atgtatggtt cttcatggaa ctatgagaga atgcagaacc taggttttct atatacaatt
    91081 cttccagtat tgaaaaaact atacccagac aaagattcag cttctcctgc aatgaaacgt
    91141 caccttgagt ttttcaatac tcatcaaaca gcggcaccat ttattcttgg agttacttcc
    91201 gctatggaag aacaagaagg aaatgaaggt gcagcttcaa ttactggtat taaagttggc
    91261 ttgatggggc cactggctgg tctaggagat agtttgttct ggctgacact agttcctatc
    91321 tgttttagta ttggtgcgtc ttattctaaa gacggcggtg ctttaggtat ctttatcgcc
    91381 ttaatattgt ttaatattat taatattcct gttaaatatt tcggtttgaa atatgggtat
    91441 actaagggtt ctagtcttat ccaagaaaat aatacaaaag gaacattgaa tcgcgttacg
    91501 agtatggcga cagcattagg gctagtacta gtgggtggtt tgattccatc aatggttggt
    91561 attaattttg gattagaatt taagcagggg gaacttgtta tttctgttca agaaatgatt
    91621 acaaaattaa ttccaggatt tatccctatg gctttgactt tattaatgtg taaattaatt
    91681 agaaaaggaa agaatccggt tgtactaatc tttagtgtta tggctattgg agttatccta
    91741 gttgttttag gaattttgaa gtagtagaaa gtgtggaggt ggtatttggg atatcacctc
    91801 cattttggaa gagaggtaaa gagtgaaatt atggtataag aaagctgcct caaattggaa
    91861 tgaagccttg ccgattggga acggtcattt aggtggtatg atttatggtt cagctacaaa
    91921 agaatgtatt caactaaacg atgagactat ttggtataga ggaaagtcag atagaaataa
    91981 tccagactca ctattgcatc ttaaaaaaat tcgggaatat cttttagatg gagaaattca
    92041 gaaagccgaa gaattgataa agttaacaat gtttgctacc ccaagagatc aaagccacta
    92101 tgaattactt ggggaacttt acattgagca tatagatatt cagtcttgtg ctctttcatt
    92161 gtatgaaaga gagctagatt tagatacagc tatttctaat gttgtgtttg agcctaatag
    92221 ttgtaattta caaataaaaa gagaatattt tacgagtttt aataagaata ttttatgttg
    92281 ccgtatagtg tcatcagttc aaaacacatt aaatttaaac attaatttgg gtagaaataa
    92341 acggtttaat gacgaagtat ctaaactgga ttcaagtaca attttaatgt cggcctctgc
    92401 tggaggtaga aaaggtgttc agtttaaagt agtatgtcat tctaaagtta cggatggtga
    92461 agtaagtgta ttgggagaga caatagttat tcggaatgct acagaggtat ttctttatct
    92521 caaatcaatg acggattatt ggggaaatat agatatttct tctcttcagg gagaatttag
    92581 tagtattgat tactttacag aaaaagatga acatgtaaaa aaatatcagg agcaatttaa
    92641 tagagttgat tttaaactag actatagtaa aggttgtctt agcattccaa cgaatctact
    92701 tcttgaaaac actaaaaagt atagtaacta cttgactaac ttgttatttc attatggaag
    92761 atatctgtta atatcgtcta gtcaaccgaa tggtttacct gccaatcttc aaggaatatg
    92821 gtgtgatgaa ttaaatccaa tttggggttc taaatatacg attaatatta atactcaaat
    92881 gaattattgg atggtaggtc catgtgattt accagaagta gaatatccat tatttgatat
    92941 gctcgaaaga atgagagaac cgggaagact aaccgctaag aaaatgtatg gagctagagg
    93001 ttttacagca catcataata cggatggttt tggcgatacg gctccccaat ctcatgccat
    93061 gggggctgca atttgggtat taactattcc atggttatgt actcatattt gggaacacta
    93121 tttatatttc caagatgagc gtattcttac ggaacatttt gaaatgataa aagaagcatt
    93181 tcttttcttt gaagattatt tatttgaggt ggatggctac ttgatgacag gtccaagtgt
    93241 ctcaccggaa aataaatatc gcttaaaaaa tggtattgaa ggaaatgctt gtctatcatc
    93301 tacaattgat aatcaaattc taagatattt ttgtgattca tgcattggca ttgcaaaaca
    93361 attaggagac aattcggatt ttattagtcg tgtgaaggag ttaaaaaaga aattacctag
    93421 aacaaaaata ggtagtaatg ggcaaataca agaatggcta gaggattatg aagaagtaga
    93481 gcctggtcat agacacattt cacctctatt tgggctttat ccttataatg agattgatat
    93541 tcataaaact ccggaattag cagaagcagc taaaatcact atcaatagga gattatcaaa
    93601 cgctaacttt ttatcttcac aggataggga gcaagcgatt aataattggt tagtaagtgg
    93661 tttgcatgct agtacacaaa caggttggag tgctgcatgg ctgattcatt tttttgcgag
    93721 actatatcaa ggtgaacctg cttataacca gattaatggt ttgttaaata atgcgactct
    93781 tggcaattta tttcttgacc atccaccatt tcaaattgat ggtaatttag gtttggtgag
    93841 tggaatttgt gaattattag tacagagcca tcataattgg ttatcactaa ttccagcttt
    93901 accttctgct tggtcagaag gagaagtgaa aggtttcaga gtaagaggag gatataaggt
    93961 atcgtttgct tggaaaaatg gggatataac attcctaaaa ttggaaggag gaaacaaaga
    94021 tcaaaaagta agagtaagaa tatatggcaa aaatactgat gtacaaaata ttgaattggt
    94081 atttaattca gaaaaaatta ttgagttaaa tttttaggta taagtcatga ataaagaaaa
    94141 aataaaaaga aaattaatca caatattgtt tgtatgtatt gggatgttat gttttggatt
    94201 gttagcagga gttaaggctg ataatcgtgt tcaaatgaga acgacgatta ataatgaatc
    94261 gccattgttg ctttctccgt tgtatggcaa tgataatggt aacggattat ggtgggggaa
    94321 cacattgaag ggagcatggg aagctattcc tgaagatgta aagccatatg cagcgattga
    94381 acttcatcct gcaaaagtct gtaaaccaac aagttgtatt ccacgagata cgaaagaatt
    94441 gagagaatgg tatgtcaaga tgttggagga agctcaaagt ctaaacattc cagttttctt
    94501 ggttattatg tcggctggag agcgtaatac agttcctcca gagtggttag atgaacaatt
    94561 ccaaaagtat agtgtgttaa aaggtgtttt aaatattgag aattattgga tttacaataa
    94621 ccagttagct ccgcatagtg ctaaatattt ggaagtttgt gccaaatatg gagcgcattt
    94681 tatctggcat gatcatgaaa aatggttctg ggaaactatt atgaatgatc cgacattctt
    94741 tgaagcgagt caaaaatatc ataaaaattt ggtgttggca actaaaaata cgccaataag
    94801 agatgatgcg ggtacagatt ctatcgttag tggattttgg ttgagtggct tatgtgataa
    94861 ctggggctca tcaacagata catggaaatg gtgggaaaaa cattatacaa acacatttga
    94921 aactggaaga gctagggata tgagatccta tgcatcggaa ccagaatcaa tgattgctat
    94981 ggaaatgatg aatgtatata ctgggggagg cacagtttat aattttgaat gtgccgcgta
    95041 tacatttatg acaaatgatg taccaactcc agcatttact aaaggtatta ttcctttctt
    95101 tagacatgct atacaaaatc cagctccaag taaggaagaa gttgtaaata gaacaaaagc
    95161 tgtattttgg aatggagaag gtaggattag ttcattaaac ggattttatc aaggacttta
    95221 ttcgaatgat gaaacaatgc ctttatataa taatgggaga tatcatattc ttcctgtaat
    95281 acatgagaaa attgataagg aaaagatttc atctatattc cctaatgcaa aaattttgac
    95341 taaaaatagt gaggaattgt ctagtaaagt caactattta aactcgcttt atccaaaact
    95401 ttatgaagga gatgggtatg ctcagcgtgt aggtaattcc tggtatattt ataatagtaa
    95461 tgctaatatc aataaaaatc agcaagtaat gttgcctatg tatactaata atacaaagtc
    95521 gttatcgtta gatttgacgc cacatactta cgctgttgtt aaagaaaatc caaataattt
    95581 acatatttta ttgaacaatt acaggacaga taagacagct atgtgggcat tatcaggaaa
    95641 ttttgatgca tcaaaaagtt ggaagaaaga agaattagag ttagcgaact ggataagcaa
    95701 aaattattcc atcaatcctg tagataatga ctttaggaca acaacactta cattaaaagg
    95761 gcatactggt cataaacctc agataaatat aagtggcgat aaaaatcatt atacttatac
    95821 agaaaattgg gatgagaata cccatgttta taccattacg gttaatcata atggaatggt
    95881 agagatgtct ataaatactg aagggacagg cccagtccct ttcccaacac cagataaatt
    95941 taatgatggt aatttgaata tagcatatgc aaaaccaaca acacaaagtt ctgtagatta
    96001 caatggagac cctaatagag ctgtggatgg taacagaaat ggtaatttta actctggttc
    96061 ggtaacacac actagggcag ataatccctc ttggtgggaa gtcgatttga aaaaaatgga
    96121 taaagttggg cttgttaaaa tttataatcg cacagatgct gagactcaac gtctatctaa
    96181 ttttgatgtg attctatatg acaataatag aaacgaagtt gctaagaaac atgttaataa
    96241 tttgtcgggt gaatctgtta gtctagattt caaagaaaaa ggagcaaggt atattaaagt
    96301 taaattacta acgagtggag tgcctttgag tttagcagaa gtagaggttt ttagagaatc
    96361 agatggtaag caatctgaag aggatataga taaaataaca gaagataaag tagtctctac
    96421 aaataaggta gctactcaaa gttcaaccaa ttatgagggt gtagctgctt tagcagttga
    96481 tggtaataaa gatggagatt acggacatca ttcggtgact catactaagg cagattctaa
    96541 cgcttggtgg caggtcgatc tgggagaaga gtttacggtt tctaaagttg atatttataa
    96601 tagaacagat gccgaacctc agcgtttatc taattttgat gttatttttc tatcttcatc
    96661 aggagaagaa gtttttagaa gacattttga taaagtagtt gatggtttgt tatctttaaa
    96721 agtaccttct gtaggggcta agctagtcaa aatagaatta aaatcagcag ctattccgtt
    96781 aagtttagcg gaagttgaag tctatggttc aaagagaact ccgaagaaac tttctaatat
    96841 tgcattaacc aaagaaactc gacagagttc aacggattac aatggttttt ctcgtctagc
    96901 agttgatgga aataaaaacg gagattatgg tcatcattca gtgactcata ccaaaggaga
    96961 ttctccttca tggtgggaga tagatttagc acaaaccgaa gaattagaaa agttaattat
    97021 ttataataga acagatgctg aaattcagag attatcaaat tttgatatta ttatatatga
    97081 ttcaaataat catgaagttt ttaaacaaca tattgacagt ttagaaagca ataatctatc
    97141 catagactta aaagggctga agggaaaaaa ggttagaatt tctttgagaa acgcaggaat
    97201 tcctttaagt ttggcagagg tagaggttta tacttataag taattttaaa aattatcatc
    97261 ggtagtatga aagaaacaga aaaataagag gaaaatagta tgattcaaca tccacgtatt
    97321 ggtattcgtc cgactattga tggtcgtcgt caaggtgtac gcgaatcact tgaagtacaa
    97381 acaatgaaca tggctaaaag tgtggcagat ttgatttcaa gcacattgaa atatccagat
    97441 ggggaacctg tggaatgtgt gatttctcca tctaccattg gtcgtgttcc agaggctgca
    97501 gcttcccatg agttgtttaa aaaatcaaat gtttgcgcaa caattacagt tacaccatgc
    97561 tggtgttatg gtagtgaaac tatggatatg tctccagata ttcctcatgc tatttgggga
    97621 tttaatggga cagaacgccc aggagctgtc tatcttgcag ctgtactagc ttcacatgct
    97681 caaaaaggga ttccagcctt tgggatttat ggtagagatg ttcaggaagc taatgataca
    97741 gatattccag aagatgtcaa agaaaaactt ttacgttatg cgcgtgcagc tcttgcaact
    97801 ggcttgatga gagacactgc ttacctatca atgggtagtg tttcgatggg gattggtggt
    97861 tctattgtaa atccggattt cttccaagaa tacttaggaa tgcgaaatga atcggtagat
    97921 atgacggagt tcacacgccg tatggaccgt ggtatttacg accctgaaga gtttgaacgt
    97981 gctatggttt gggtaaaaga acatatcaaa gaaggagttg accgaaatcg tgaggatttg
    98041 attctttcta aagaagagaa agaaaaacaa tgggaatttg ttattaagat gttcatgatt
    98101 ggacgtgact taatggttgg taacccaaga cttgctgaac ttggttttga ggaagaagca
    98161 gttggtcacc atgctttagt agctggtttc caaggtcaac gtcagtggac agaccatttt
    98221 ccaaatgggg actttatgga aactttcctc aatactcagt ttgactggaa tggtattcga
    98281 aaaccatttg tatttgcgac agagaatgat tcactaaatg gtgtgtctat gctctttaat
    98341 tatctattaa caaatactcc acaaatcttt gctgatgtgc gtacttattg gagtccagag
    98401 gctgttgaac gtgtaacagg atatacttta gagggtcgtg ctgcagctgg attcttacat
    98461 ctaatcaact ctggatcttg tacattggat ggtacaggtc aagctactcg agatggcaaa
    98521 cctgttatga aaccattctg ggagttggat gaaagtgaag tacaggctat gcttgaaaat
    98581 acagacttcc caccagcaaa ccgcgaatac ttccgtggag gaggattctc aactcgtttc
    98641 ttgacgaagg gggatatgcc agtaacaatg gtacgtctca atcttctaaa aggggttggt
    98701 ccagtgctac aaattgcaga aggttacaca cttgaacttc ctgaagatgt tcaccatact
    98761 ttagataatc gtacagatcc aggatggcca actacttggt ttgctccacg tttgacagga
    98821 aaaggtgctt tcaagtctgt ctatgacgtc atgaataatt ggggagctaa tcacggagcc
    98881 ataacatatg gccacattgg agcagacttg attaccctgg cttctatgtt gagaattcct
    98941 gtcaatatgc ataatgtacc tgaggaagat atctttagac ctaaaaattg gtccttattt
    99001 ggaacagaag atctagaatc agcagactat cgtgcatgtc agttgttggg accactacat
    99061 aaataaaact tgtttatata ggaggtaaac ttacgtccct cctatccttt taaaaatatt
    99121 tgttaaacaa ttcacaaata attgaaaacg aatacaaaaa gtaatataat gatgttaaat
    99181 agatagcgca aaggcgcagg aggaaaatta tatggctaca ttttatgttc cggcagtcaa
    99241 ccttattggt aaaggtgttg taaatgaagt gggtccttat atcaaggaac ttggctataa
    99301 aaaggcactt ttggtgacag ataagtacat cgaaggcagt gatattttac ctaagacttt
    99361 aaaaccactg gatacagaag gaatcgaata tgtcatcttt agcgatgtag agccaaaccc
    99421 tacttgtaaa aatgtcacag atggggtagc tgctttgcaa gaacatggct gtgactttat
    99481 catcagtctt ggcgggggtt ctccacagga tgcagctagt tgtatttcta tcatggctac
    99541 aaatggtgga agaccacagg attatgaagg gcttcataag tctgctaaaa aaggcttgcc
    99601 agttgtggcg atcaatacaa cggcaggtac atcagcagaa attaccatta actatgtgat
    99661 tactgatgaa gaacgcaagg ttaagatggt aatggttgac aagaatagcc ttgctcttat
    99721 ctctgttaat gacccggaac tcatgctttc caaacctaaa ggcctgactg ctgctactgg
    99781 tatggatgct ctgactcacg ctgttgaagc tttggtaaca cctggtgctt atgatgtaac
    99841 caagaaactg tctattggtg ctattgagct tatcaaggaa tatcttcctc gtgctgtaga
    99901 aaatggacat gatattgaag cgcgtgaagg tatggtcaat gccatcttcc ttggtggtat
    99961 gagctttaat aatgctggtc ttggctatgt tcactcaatg gctcaccaac tcggtgcagt
   100021 atataatttg ccacatggtg tttgctgtgc catgttgcta ccagttatag aacgtgaaaa
   100081 tgctaaacgt gtaccagaag ctttccgcaa tgttgccaaa gccttgggac ttcatgtaga
   100141 aggtaaatca gatcaagaat gtgccgatta tgcgattgct gagattgaga agctttctga
   100201 gacagtaggt attcctaaga aactgactga acttggtatt gaagaaaaag atttcgactt
   100261 tgaatacctt tctaagaatg ccttgattga tgcctgcgca ccaggaaatc catttatgcc
   100321 aaccttagaa gaaacgattg ccttttataa agagttattt tagcaagaga ttggacgaca
   100381 ataggacaat tcacctctaa ttattgacat ttcaggaaaa atcgcagtaa aaacggcaca
   100441 gccttcttta aatgtgctat aatactagaa aaatacttgt ggaggttcca ttatggcaat
   100501 atttttcatg atttttctga ttgtttgtgt gctcctattg gtgatagtca cactgagtac
   100561 agtttatgtg gttcgtcagc agtcggtggc gattattgaa cgctttggga aataccaaaa
   100621 ggttgctaat agcggtattc atattcgctt gccttttggg attgactcga ttgcagcacg
   100681 gattcagttg cgcttgttgc aaagtgatat tgtggttgag actaagacca aggacaatgt
   100741 gttcgttatg atgaatgtag cgactcagta ccgtgtcaac gagcagagcg tgacagatgc
   100801 ttactataaa ctcatacgtc cagaatctca gattaaatct tatatcgaag atgctcttcg
   100861 ctcttctgtt ccaaaattaa ccttggatga attgtttgag aaaaaagatg agattgccct
   100921 tgaagttcaa caccaagtag cagaagaaat gaccacttac ggctacatta tcgtgaaaac
   100981 cttgattacc aaggtcgaac cagatgcaga agttaagcaa tccatgaatg aaatcaatgc
   101041 ggcgcaacgt aagcgggtcg cagcacaaga attggcggaa gctgacaaga ttaaaattgt
   101101 cactgcagct gaagcagaag cagaaaaaga ccgccttcat ggtgtgggga ttgcccaaca
   101161 acgtaaggcg attgtggatg gattggcaga gtctatcacc gaactcaagg aagccaatgt
   101221 tggcatgaca gaagaacaaa tcatgtctat cctcttgacc aaccagtatt tggatacctt
   101281 gaataccttt gcctctaaag gaaatcaaac catcttttta ccaaatactc caaatggtgt
   101341 ggatgatatc cgaacacaaa tcttgtcagc ccttcgcgct gagaagaaat aatagactaa
   101401 tactcttcga aaatctcttc aaaccacgtc agcgtcgcct tgccgtatat ttgagctgac
   101461 ttcgtcagtt ctatctgcaa cctcaaaaca gtgttttgag ctgacttcgt cagtcttatc
   101521 tactacctca aaacggtgtt ttgagcaacc tgtggctagt ttcctagttt gctatttgat
   101581 tttcattgag tacaaagagc ttggcaacag gctctttttg tattgcgttt attaagaaaa
   101641 acaaaaaaca tagatataca tttaactaaa aattattgta tgttacctcc cttaattagg
   101701 aatgataagg gaataactag aaagatttgt gaatacaaac tatttctgat atacaaaata
   101761 tacagtaata atgaatgatg ggagatggga tgaaagaatt tcaatttgag agaaagcagc
   101821 gtttttcttt gaggaaatat gcaataggag cttgttcggt cttgctagga acgagtttat
   101881 tttttgctgg tatgggtgat cagcctgtac aggatacaga aacgagttca gcactaattt
   101941 caagtcatta tttggatgag caggatttat ctgaaaagct gaaatctgag ttgcaatggt
   102001 ttgaattaga aaacaagctt ttgaacttat gggagcatta ggttactatg aaggatttgt
   102061 tccttatgtt tcaaatcaat acaaaaacca agctgaagaa gaaggcaaac cgctatctga
   102121 taaatatatt ttcgaaaaaa tcttaggaaa aacatatgca gccttcaaaa aagatcaaat
   102181 taatgagcgt gtcgagaaat taggtaagtt aaaacctatt acaataaatt acaacggaaa
   102241 atcagaagta attgatagta aagaaaaatt acaagagctt atgaataaag ccgttaaaga
   102301 cgaagtggct caaatatagt aaaatgaaat a
//
LOCUS       DAVAGB010000003        62599 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVAGB010000003 DAVAGB010000000
VERSION     DAVAGB010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 62599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62599
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.003"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(<1..463)
                     /locus_tag="VQO19_000247"
     CDS             complement(<1..463)
                     /locus_tag="VQO19_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348564.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFQFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLYFDQDASLSALLLDEDYYNILVHVKETIQGYSVLSNCG"
     gene            complement(453..1448)
                     /locus_tag="VQO19_000248"
     CDS             complement(453..1448)
                     /locus_tag="VQO19_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348565.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENISYVIWQRKFNQLSLPLSQHVLKGKMLEIWKYRPF
                     VSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRIEEESEALENMILQYLGEDDAS"
     gene            complement(1856..2281)
                     /locus_tag="VQO19_000249"
     CDS             complement(1856..2281)
                     /locus_tag="VQO19_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348566.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEHMTTGDILIEAFKV"
     gene            complement(2410..2769)
                     /locus_tag="VQO19_000250"
     CDS             complement(2410..2769)
                     /locus_tag="VQO19_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348567.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKVMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMSLG"
     gene            complement(2815..3021)
                     /locus_tag="VQO19_000251"
     CDS             complement(2815..3021)
                     /locus_tag="VQO19_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348568.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            complement(3008..3169)
                     /locus_tag="VQO19_000252"
     CDS             complement(3008..3169)
                     /locus_tag="VQO19_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET1348569.1"
                     /translation="MNMINVCDVGKRIKELRIPSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(3515..4471)
                     /gene="lytA"
                     /locus_tag="VQO19_000253"
     CDS             complement(3515..4471)
                     /gene="lytA"
                     /locus_tag="VQO19_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET1348570.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(4847..6217)
                     /locus_tag="VQO19_000254"
     CDS             complement(4847..6217)
                     /locus_tag="VQO19_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET1348571.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWVVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSTFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(6524..7690)
                     /gene="recA"
                     /locus_tag="VQO19_000255"
     CDS             complement(6524..7690)
                     /gene="recA"
                     /locus_tag="VQO19_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HET1348572.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(7745..9001)
                     /locus_tag="VQO19_000256"
     CDS             complement(7745..9001)
                     /locus_tag="VQO19_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HET1348573.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGNKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFEGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(9086..10102)
                     /locus_tag="VQO19_000257"
     CDS             complement(9086..10102)
                     /locus_tag="VQO19_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET1348574.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(10110..10628)
                     /locus_tag="VQO19_000258"
     CDS             complement(10110..10628)
                     /locus_tag="VQO19_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET1348575.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLID"
     gene            complement(10618..11061)
                     /gene="tsaE"
                     /locus_tag="VQO19_000259"
     CDS             complement(10618..11061)
                     /gene="tsaE"
                     /locus_tag="VQO19_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HET1348576.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILIGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(11147..11767)
                     /locus_tag="VQO19_000260"
     CDS             complement(11147..11767)
                     /locus_tag="VQO19_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348577.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(12150..13013)
                     /locus_tag="VQO19_000261"
     CDS             complement(12150..13013)
                     /locus_tag="VQO19_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET1348578.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDNLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            13685..13981
                     /locus_tag="VQO19_000262"
     CDS             13685..13981
                     /locus_tag="VQO19_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000911560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET1348579.1"
                     /translation="MLKFRKVVASSLAVLAFSLALPVLAVSHRGGEWTYGGHHDPYNW
                     GAFSNYYHGSQYHWAYVGSNERDNQKTVYAGAHSAAYAFVNTNLGERITFDAGW"
     gene            14084..16099
                     /locus_tag="VQO19_000263"
     CDS             14084..16099
                     /locus_tag="VQO19_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET1348580.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFGALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLTI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNFITSTEWHDY
                     SPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEDHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            16101..16733
                     /locus_tag="VQO19_000264"
     CDS             16101..16733
                     /locus_tag="VQO19_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1348581.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            16874..17152
                     /locus_tag="VQO19_000265"
     CDS             16874..17152
                     /locus_tag="VQO19_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HET1348582.1"
                     /translation="MKKFDNYIIEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(17662..18075)
                     /gene="ndk"
                     /locus_tag="VQO19_000266"
     CDS             complement(17662..18075)
                     /gene="ndk"
                     /locus_tag="VQO19_000266"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HET1348583.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYLPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(18186..21863)
                     /gene="rpoC"
                     /locus_tag="VQO19_000267"
     CDS             complement(18186..21863)
                     /gene="rpoC"
                     /locus_tag="VQO19_000267"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HET1348584.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKTEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPTVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(21896..25507)
                     /gene="rpoB"
                     /locus_tag="VQO19_000268"
     CDS             complement(21896..25507)
                     /gene="rpoB"
                     /locus_tag="VQO19_000268"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET1348585.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            25923..25993
                     /locus_tag="VQO19_000269"
     tRNA            25923..25993
                     /locus_tag="VQO19_000269"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:25955..25957,aa:Cys,seq:gca)
     gene            complement(26191..27522)
                     /locus_tag="VQO19_000270"
     CDS             complement(26191..27522)
                     /locus_tag="VQO19_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HET1348586.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVYQIGEDTYIVQGTMTLNDFNNYFNVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELISQNKQFILTNDKVKNGRVTKVKIQITEVEIEEETE"
     gene            complement(27813..28637)
                     /gene="endA"
                     /locus_tag="VQO19_000271"
     CDS             complement(27813..28637)
                     /gene="endA"
                     /locus_tag="VQO19_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HET1348587.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     APEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSNATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(28676..28864)
                     /locus_tag="VQO19_000272"
     CDS             complement(28676..28864)
                     /locus_tag="VQO19_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET1348588.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(28857..30140)
                     /gene="murA"
                     /locus_tag="VQO19_000273"
     CDS             complement(28857..30140)
                     /gene="murA"
                     /locus_tag="VQO19_000273"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET1348589.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(30164..30394)
                     /locus_tag="VQO19_000274"
     CDS             complement(30164..30394)
                     /locus_tag="VQO19_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HET1348590.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTAENTRKVRV
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(30452..31489)
                     /locus_tag="VQO19_000275"
     CDS             complement(30452..31489)
                     /locus_tag="VQO19_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HET1348591.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(31473..31961)
                     /gene="coaD"
                     /locus_tag="VQO19_000276"
     CDS             complement(31473..31961)
                     /gene="coaD"
                     /locus_tag="VQO19_000276"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HET1348592.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDKLVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(31951..32490)
                     /gene="rsmD"
                     /locus_tag="VQO19_000277"
     CDS             complement(31951..32490)
                     /gene="rsmD"
                     /locus_tag="VQO19_000277"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HET1348593.1"
                     /translation="MKIISGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(32555..33547)
                     /locus_tag="VQO19_000278"
     CDS             complement(32555..33547)
                     /locus_tag="VQO19_000278"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HET1348594.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(33660..34343)
                     /locus_tag="VQO19_000279"
     CDS             complement(33660..34343)
                     /locus_tag="VQO19_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HET1348595.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(34399..35139)
                     /locus_tag="VQO19_000280"
     CDS             complement(34399..35139)
                     /locus_tag="VQO19_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HET1348596.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            35173..35451
                     /locus_tag="VQO19_000281"
     CDS             35173..35451
                     /locus_tag="VQO19_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HET1348597.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            35529..36455
                     /gene="yidC"
                     /locus_tag="VQO19_000282"
     CDS             35529..36455
                     /gene="yidC"
                     /locus_tag="VQO19_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET1348598.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPLLLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFST
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(36530..37324)
                     /gene="pflA"
                     /locus_tag="VQO19_000283"
     CDS             complement(36530..37324)
                     /gene="pflA"
                     /locus_tag="VQO19_000283"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HET1348599.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKQLMDTESYQDYMKRVHG"
     gene            complement(37450..38700)
                     /locus_tag="VQO19_000284"
     CDS             complement(37450..38700)
                     /locus_tag="VQO19_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HET1348600.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGLHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(38767..39594)
                     /gene="purR"
                     /locus_tag="VQO19_000285"
     CDS             complement(38767..39594)
                     /gene="purR"
                     /locus_tag="VQO19_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HET1348601.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(39861..40802)
                     /locus_tag="VQO19_000286"
     CDS             complement(39861..40802)
                     /locus_tag="VQO19_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HET1348602.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(40792..42048)
                     /locus_tag="VQO19_000287"
     CDS             complement(40792..42048)
                     /locus_tag="VQO19_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HET1348603.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(42050..42712)
                     /locus_tag="VQO19_000288"
     CDS             complement(42050..42712)
                     /locus_tag="VQO19_000288"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HET1348604.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKGAQYFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(42675..43331)
                     /locus_tag="VQO19_000289"
     CDS             complement(42675..43331)
                     /locus_tag="VQO19_000289"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET1348605.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(43342..44220)
                     /gene="rsgA"
                     /locus_tag="VQO19_000290"
     CDS             complement(43342..44220)
                     /gene="rsgA"
                     /locus_tag="VQO19_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HET1348606.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(44222..45094)
                     /gene="rsmA"
                     /locus_tag="VQO19_000291"
     CDS             complement(44222..45094)
                     /gene="rsmA"
                     /locus_tag="VQO19_000291"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HET1348607.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(45225..45533)
                     /locus_tag="VQO19_000292"
     CDS             complement(45225..45533)
                     /locus_tag="VQO19_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348608.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(45526..46167)
                     /locus_tag="VQO19_000293"
     CDS             complement(45526..46167)
                     /locus_tag="VQO19_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1348609.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(46169..48199)
                     /locus_tag="VQO19_000294"
     CDS             complement(46169..48199)
                     /locus_tag="VQO19_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET1348610.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSVYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEKGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(48468..49367)
                     /locus_tag="VQO19_000295"
     CDS             complement(48468..49367)
                     /locus_tag="VQO19_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET1348611.1"
                     /translation="MLIGQKIKEIRIEKGVSRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQ
                     LIGDEFLVKKLTEEWQEDVKKYL"
     gene            complement(49439..49999)
                     /gene="rnmV"
                     /locus_tag="VQO19_000296"
     CDS             complement(49439..49999)
                     /gene="rnmV"
                     /locus_tag="VQO19_000296"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HET1348612.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINAQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMMVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(49999..50772)
                     /locus_tag="VQO19_000297"
     CDS             complement(49999..50772)
                     /locus_tag="VQO19_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HET1348613.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(51068..51742)
                     /locus_tag="VQO19_000298"
     CDS             complement(51068..51742)
                     /locus_tag="VQO19_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET1348614.1"
                     /translation="MTILGKDTVQQSAKGESVTQEATPEYKPETTLGVDKGGNTGSSD
                     ANANAGGGSQAGGPAHTGSQNSAQSQASKQLATEKESAKNAIEKAAKDKQDEIKGAPL
                     SDKEKAELLARVEAEKQAALKEIENTKTMEDVKEAETIGVQAIAMVTVLKRPVAPNAA
                     PKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALASLGLVAATSGFALLGRKTR
                     RRKWNS"
     gene            complement(52005..52139)
                     /gene="rpmH"
                     /locus_tag="VQO19_000299"
     CDS             complement(52005..52139)
                     /gene="rpmH"
                     /locus_tag="VQO19_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HET1348615.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(52284..53498)
                     /locus_tag="VQO19_000300"
     CDS             complement(52284..53498)
                     /locus_tag="VQO19_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET1348616.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(53654..53947)
                     /locus_tag="VQO19_000301"
     CDS             complement(53654..53947)
                     /locus_tag="VQO19_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348617.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            54109..54561
                     /locus_tag="VQO19_000302"
     CDS             54109..54561
                     /locus_tag="VQO19_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HET1348618.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(54596..55984)
                     /locus_tag="VQO19_000303"
     CDS             complement(54596..55984)
                     /locus_tag="VQO19_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET1348619.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            56050..57012
                     /locus_tag="VQO19_000304"
     CDS             56050..57012
                     /locus_tag="VQO19_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HET1348620.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVNTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(57218..58228)
                     /gene="ccpA"
                     /locus_tag="VQO19_000305"
     CDS             complement(57218..58228)
                     /gene="ccpA"
                     /locus_tag="VQO19_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HET1348621.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(58653..59252)
                     /locus_tag="VQO19_000306"
     CDS             complement(58653..59252)
                     /locus_tag="VQO19_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET1348622.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLMLQPDVESVFQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRAEKLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERNIADLMQTLHTVLEGRKEYSPELMEVVMMHPNPLTEQEIAVLKGIAQGFSNQEIA
                     DKLYLSNGTVRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(59253..60350)
                     /locus_tag="VQO19_000307"
     CDS             complement(59253..60350)
                     /locus_tag="VQO19_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET1348623.1"
                     /translation="MLERLKRIHYMFWISLIFMIFPILSVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGLMLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVRSLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILTFVDLMTFGLVRIRIVEDLKEAQ
                     VKQNAQINLLLAENERSRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVQVENHLDKSSLTQEL
                     ESTASMILLELVTNIIKHAKASKVYLKLERTEKELILTVRDDGCGFASISGDELHTVR
                     NRVFPFSGEVSVISQKHPTEVQVRLLYKERK"
     gene            complement(60350..61087)
                     /locus_tag="VQO19_000308"
     CDS             complement(60350..61087)
                     /locus_tag="VQO19_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET1348624.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTAIFSFPVVLHTDKINNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFSVGHFVRGVDMSLGNWIGAALLLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQVVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSVVLFGLTIYLQGHKENA"
     gene            complement(61089..61973)
                     /locus_tag="VQO19_000309"
     CDS             complement(61089..61973)
                     /locus_tag="VQO19_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1348625.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(61960..62154)
                     /locus_tag="VQO19_000310"
     CDS             complement(61960..62154)
                     /locus_tag="VQO19_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348626.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIRGALGFGFM
                     IFVVFLMGMEWLKGESHDGG"
     gene            complement(62151..62357)
                     /locus_tag="VQO19_000311"
     CDS             complement(62151..62357)
                     /locus_tag="VQO19_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348627.1"
                     /translation="MGEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT        18306 a        14106 c        11539 g        18648 t
ORIGIN      
        1 gaccacaatt actcaatacc gaatacccct gaatggtttc ttttacatgc accaatatat
       61 tataataatc ttcatccaat aataaggctg ataaactagc atcttgatca aaatataagg
      121 gaatttctcg accgtccttc tttaatggat attctggtaa gatactaaat agttcaatca
      181 tagaaggaaa ctcaggatta gttgttgtaa attgaaaaag ctgcgctttc tcatctttct
      241 gacttccttg atactctccc aattctaaaa aatgattcaa ggtagtataa aattccttat
      301 tttttacttc atcaatgatg accatatcat aatcttttgt tgtgcgactt ttaaatcctt
      361 gcgaatccaa tacgatagag gtagcagttc ccccaatcag aacataatag ttctgaaaat
      421 ccgcaaacat ttcttgaaaa ataactttcg tattagctgg catcatcttc tcccagatac
      481 tgtaatatca tattttctag tgcttcactc tcttcctcta tacgtgggtc atcatcatct
      541 tttaaggtca aataaagaga aatcggatct acaaattgtt tatcatgatt atttttaaaa
      601 tcattccaaa actcagatac aaaaggacga tatttccata tctctagcat ctttcctttt
      661 aaaacatgct gagaaagtgg caaggataac tgattgaatt ttctctgcca tatgacatag
      721 ctaatatttt catccgtttc agctaaaaaa gttgaatgcg acaaagcata agcaccacca
      781 tatagaagat tagaaacaga ttttatctgc tttatatcgc catctggcaa taaaatccgt
      841 tttttgatgg gattaaataa acatgacacg gattttaaga ataattcttt ctttgacacc
      901 gtatatgtgt aaagcttatt ttgcttgttt aaccaatata aagctttaaa agtcctcaaa
      961 cacctataaa ttgttgagtt tggaagtcca gtgacttgtg aaagcaaatc aacatctact
     1021 actttttgac cttttgtcaa taaaaaggca atccacgtta attgttcgct aggtgttaat
     1081 tccttaggga cttcagtatc attcgcattc agtactagtc ccaatggagg gaagaagagg
     1141 tttcccttaa agtctacaaa cggaactcta gcttgaagta attgcttttt ttcactgtct
     1201 gataacttcg aaaacaccaa aacaacatcc atattggctt tttcacccat agtgcgagcc
     1261 tgagtaacaa atgaactcaa actccccctt ctcttttctt taatcaataa aaatgattcc
     1321 ttatgaaaag tcatttgagt atactcaaac ctttttacaa aactgattgg taaagtcaaa
     1381 gtcagttcct caatactgac atcaacataa aaggattgaa aaattgacat tatctttttg
     1441 acattcatgt tttttcctta ttctatcatt tttattatat tttatcattc ggtataataa
     1501 aatataagtt ttttgataaa ataaccaaaa actactcgct atcccctctc acattaccct
     1561 acatatcgtt tgacatgcga ctgatagttc aggaaaactt caaggagaac ttttctctca
     1621 tccactatgc aggacttact atttcacttc tactcctata ggctcaattt gacacttttc
     1681 tttttcgaat tgctcatatg cctcctgaat agtgagttcg atttatccaa atttattttt
     1741 gtctattttg atgaatactt ccacgaagat agtctgaaaa tgaatttgca ccaattttcc
     1801 ttctcttttt aagcatatta ttccagatat gattgccctc ttgttcagta ataaattaca
     1861 ctttaaacgc ttcaatcagt atatctcctg ttgtcatatg ttctaaagaa aattcttcta
     1921 catatgattt aacatctctt aggttattac ttcctaatat cccattatgc tttttcgcta
     1981 aggaaataga agccgcttct cccttaccaa taatcttgtt actatcatga tttcttgtta
     2041 aatctctata taatgcgtat tcttcagttc caatgtctat gctcacaatc tcagctgaac
     2101 ccttagctac caactggtct atcctagatt ttaaatgggg aattgtaggt atattgattt
     2161 catcatacac ctcttgtgga ataacaattt tacccgaata gagcttttct aaaagatgtt
     2221 cagtgccaac ccataaaaat actgaaatac aatctgcatc aataaataca cgactagtca
     2281 aacgacaact cccccctctt catctagccc atatacaata tcatatctga aagcatctag
     2341 taacagttcc tcatacttcc cttgcgaaat tctgttattt tctaaaagtt gttcagttga
     2401 attaatatat tatcctaatg acatttcctt tttactttct gacaaaggac gatataaact
     2461 tgtatcatag cctaatcttg aagctgtctc tataacacta atatccatat ttttaatttc
     2521 ttctgcatca aggtatccat cattcctcaa tctatataac ataactttat gactgatacc
     2581 ataaaactga cccaatttta taatatcttc tacttcaaga tgagttctat tggcattttc
     2641 tctgatttcc tcaaccatcc tatacagtga agatgggaaa attaaaaaat aagaagcaaa
     2701 ctgatccgct tttctttcag tttcatctcc ttcaccaatc aagataagac tgactgaact
     2761 cttcttcacc tcatcataat aaagatgata cagtccatgt gctaaagaaa atctttacct
     2821 tcctaatggc atatctgaat tgactgcaat gagactgaac tgagttcctt tataacagac
     2881 tccgctaata ttctttccga gtccataaaa taccagcgtc aaattttcta tcttttgtac
     2941 caatttaaaa atatctatcg gcgattcacc atcagctccc aacttttttc taagatttgg
     3001 agctttatta cttaaatcca ttcgtgatat tcctttcacc tttttccatt ttggcaatca
     3061 tgctttgatt caaagacaaa tactcagcaa tcttatcttg agtaagattt gaaggtattc
     3121 taagttcttt tattcttttt ccaacatcac atacatttat catattcata cacctctcat
     3181 aaaaagaata gcacactctt gtcataattt tttaaataaa aaaattatga caaaacaagg
     3241 aagcaattta ttgatgctgc ttaaaaatct aaaattgatg agttcctatc aaaaatcgta
     3301 tcttcaacct caaaacagta cttaaagcta tccgactcgg tttacattgt caaatttaga
     3361 ttttatttga gcataacttt ctagtttgct ttttgatttt tgtttaatat agtagcaaaa
     3421 attgaaggaa atatctccac aagaaaacgc atactattaa gctttttcaa gacctaataa
     3481 tatgcgctgt tctgatttga aagatattcc attattattt tactgtaatc aagccatctg
     3541 gctctactgt gaattctggc ttgtctgcca gtgttccgtc tggtttgagg tagtaccagc
     3601 ctgttccgtc cgctgactgg ataaaggcat ttgataccat ggcgccttct ttagcgtcta
     3661 agtagtacca agtgtccttg tacttgaccc agcctgtctt catggcacct tcttcgttga
     3721 aatagtacca cttatcagcg attttcttcc agcctgtagc catttcgcct gagttgtcga
     3781 accagtacca gttgccgtct gtgtgcttcc tccagcggtc tgcaagcata tagcctgaac
     3841 tgtcaaagta gtaccaagtg ccattgattt tctcaaactt gtcttttgga taagagccgt
     3901 ctgaatgtac gtaccagtag ccagtgtcat tcttctgcca gcctgtttca atcgtcaagc
     3961 cgttctcaat atcatgctta aactgctcac ggctaatgcc ccattttgcc aagtaagggt
     4021 atggatccac atggtctgag tggttgtttg gttggttatt cgtgcaatac tcgtgcgttt
     4081 taattccagc taaactccct gtatcaagcg ttttcggcaa acctgcttca tctgctagat
     4141 tgcgtaagag ttcgatataa aggcggtagt ccgtcatgaa ctcttcttta gttgaatggc
     4201 tttcaatcag ttcaaccgct gcataggtct cagcattcca accgccccca acgtcccagg
     4261 caccattatc aacaggtcct acctgcatga tgcaaccgtt cccaacaatg tgcgagaaaa
     4321 aacctaattc tgggtctttc cgccagtgat aatccgcttc attctgtacg gttgaatgcg
     4381 gattcccagt tgagtgtgcg tgtacttgcc tatatggttg cacgccgact tgaggcaaat
     4441 ctgttcttaa tttactcaca ttaatttcca tattctactc cttatcaatt aaaacaactc
     4501 attttttaca atccagaacc agaaactcct ttatttctac cttacaaaga agacaatctt
     4561 agtcacgatt aggcttgtag atagaacttc aaaacgcact attttgacac tgtaaatagg
     4621 actgacaagg tctgcattct atctacaata acaccccaga ctaaaaagct tttcaaaagt
     4681 atatttttac agtctctata tgtccttttc ataaatacta tactttatta tatcatataa
     4741 aagaagtcaa aagtctgtta aactattttc aacaccaaac taaagacgag aacacaagtt
     4801 ttttcgattt tcactagagg aaatggattt tattcagtaa atccaactag gattgcactt
     4861 tggttgccaa gattgccttg ccttctttta tcaagggatg acggaataat gagaagtaca
     4921 gttgaactgt catggcaacc cagataagag gttcacaaag gataacaccc ttatatcctg
     4981 cccaaggaat aatcaaaacc acaaaaacga tttttccgat tagttcaata aagctagaaa
     5041 ctagaggaag gatcttttgc cccaagccct gcaagcaatt gcgataaatc aacaagaggc
     5101 tcaaaatggg ataaaaggtt gaactgattt gcagatagag acttccattt tctatcaagt
     5161 aaccatctgt cgaactagcc aagaaggaaa ccaaagctgg actggcaaaa aagaggaaaa
     5221 tacaaacaaa aactacccag gatatactta aacgactgcc gattcgaaga ccttgaacaa
     5281 tacggtcagg tcgcttagct cctagattct gagaagcaaa ggtcgtcatt gatgcagaaa
     5341 tagcggtcat aggaagaagg gcaaaggtca taatgcgtcg agctgccgtc tgggcactaa
     5401 taatcactgc accaaatgta ttaacagaaa actgtaaaat cacactgccg atagatacaa
     5461 ttgaactcat caagcccata gccaaacctt gctccaagag atccgcgtac aagcttttgt
     5521 cccatttgaa atgtttaaac tgtggcaaga gttctggcac acttttacga atataataaa
     5581 agcagagaac cgctgataaa ccttgcgaaa taatggtagc aagtcctgcg gattgaactc
     5641 ccagatgcaa ttgcgtaata aaatagagat ccagaaccac attaaccaag gcagagaaaa
     5701 tcagaaatcc cagggctgct agactgtcac caatagaccg caacaagcct gcaaaaagat
     5761 tataagcaaa gctgacacct acacaggtca caatcataga aatatattga taagattgag
     5821 gaagaatttc tgcaggagta tctaagtatt gcaagagagg atacaagcca agaaagccca
     5881 gcaacataac tagaatgctc aaaagagcac ctaaaatcca ggtggctgct actgcttcct
     5941 tgattttagt gaaattccga gccccataat aacgagcaat gacaatcccc atgccattgc
     6001 caacaccaag tgtaaagcct acaatcaggt caaaaatcgc tgtcgtcgct cctactgcag
     6061 ccaaggattc ttgaccaaga aatcgtccaa caatcaagac atcagcagtg ttatagagct
     6121 gttgaaaaat atttgatagc aagattggaa aggtgaagct taagagcgag ggaagaatcg
     6181 gaccatgtat caggtccact gttcgttttt tattcataaa gctattatat cagctttcca
     6241 gaggagcgac aagaaacagc aaacttatat atagcggaat gaaataagga cagtcaaatc
     6301 gatttttaac aatgttttag aagtagatgt gtactattct agtttcgatc tattatagtt
     6361 ggttgagttt ggaatagtac gctgtagctg ctaaaacatt tctagaaatt aatttgactt
     6421 tcctaataaa gttgttcata tcttatttca agctactata tataatctaa aaacttgaat
     6481 caaaaatcga aaaagtagcg gatttctcca ctgctttaac agcttattct tcaatttcga
     6541 tttcaagttc atcgcctaag tcaagcggaa cttcttcatt cactgcttct tctttctttg
     6601 gctcatcttt tttgttttca gtatcttgtt ctgaaacttc ttctccatca atcaagccaa
     6661 atttagaacg gacttgctta tcaatttcat caaagatttc tgggtgctct gccaagtatt
     6721 tcttagcatt ctcagaacct tgcccaattt tttcatcttt gtaagaatac caagcccctg
     6781 cttttttgat aatatccaaa tcgcttgcaa tcttcaaaag ctcaccagtc ttagaaattc
     6841 cttctccgta cataatttca actacggctt ccttaaacgg tggagctacc ttatttttta
     6901 caaccttaat cttagtttct ttaccgacat tggtttcttt ttgatcacca gttcccttaa
     6961 tttgtgtatt accacgaaca tccaagcgga ctgaagcata gaatttcaaa gcacgtccgc
     7021 ccggtgttgt ttctggattt ccaaacatca ctccaacttt ttcacgcaat tggttgataa
     7081 aaatggcaat tgttttggtt ttattgatag aggcgccaag tttacgcatg gcctggctca
     7141 tcatacgagc ctgcaaacca acatggctat ctccgatatc tccatcaatt tccgcacgag
     7201 gaacaagggc agcaactgag tcgactacga caagatcaac tgcacctgag tcaatcaatt
     7261 ttcccgcaat ctcaagacct tgctctcctg agtctggttg agacaagagc aattcgtcaa
     7321 tattgacacc aagggccgca gcataagctg gatcaagggc atgttccgca tcgataaagg
     7381 cagcaatccc accttctttt tgcgcttgtg caactgcatg aagggcaacc gttgtcttac
     7441 cagatgactc tgggccatag atttcgatga tacgtccctt aggataacca cctgagccaa
     7501 gggcaatgtc aagagctaaa gaacctgagc tcatcacttg caccttttgc tccgcacgtt
     7561 cacccaaacg catgattgat cctttaccaa agtctttctc aatcaattta agagcgtcat
     7621 tcaaggcctt ttcacgttct gccccaaatt tttttgaaat ttcttctaat ttttttggtt
     7681 ttttcgccat tctattctcc tacattctaa tgatcctcag acctatctac tattatatca
     7741 aaagttagtc acttaataaa gccttgcgaa ctaggttaaa ggcatgcata accgcaatgt
     7801 gacgtacatc tgctcggctt ctgcctccaa tattaacctt gataacctca gttccttgat
     7861 cttgcgccaa gcctatgaag actgtcccaa ctgggtgtcc ttctaggcta tctggtcctg
     7921 ccactccagt caaactaatt ccaaaatcag actgggtctt gcttcgtgcc tgctcagcca
     7981 tcttctgagc tgtaaattca gacaccacac catgttcttc caaattcttg gcaggaatat
     8041 ccaacatcct tgatttttcc tccaagctat aggtcacaaa accaccctca aatatacttg
     8101 aaactccaga aaaattcgcc acggtagctt ggaaaagacc tgccgtcaaa ctctctgcag
     8161 ccgcgatggt tttcccttgc cttttcagtt cttctaccac aatgctggct aaactagttt
     8221 cttccccata accatagcaa aagtctcgta aagaaattcc ttcgaaagtc tggcagtcca
     8281 agatttgatt ttccaagata tccagcgctt gattcgcctc ttcttgactg ctagcctttg
     8341 ttgacagacg tagagtgact tctcctgtct tggcataagg ggccaaggta ggatcgatct
     8401 gattatcaat taaatcagcc aaaatcgtaa ccaactggct ctcgccaatc ccaaagaaac
     8461 gaagaactcg ggaatacagc ttgttccctg tcatcaactt gggtagaagt tggtttaaga
     8521 ccatgggttt caattcactt ggcggacctg gaaggacgac ataggtcact ccgtctactt
     8581 ctaattttcc tccaacagcc agtcctgttt cgtttggcag tggaatcgct ccttctacaa
     8641 tttgagcttg tctttcgtta ttcggtgttc gggcatagtc tggtcgcagg gcaaaaaaga
     8701 tatccaactt ctcctgagcc tgaggatcaa agactaatgc tttccctaaa aatttagcta
     8761 gggtttgttt ggttaggtcg tcctcagttg gccccaaacc gcctgtcaaa atcaccagac
     8821 tgctacgttg actggcaatc tcaagcaaag acaagagacg aacttcattg tctcctacag
     8881 ccgtctgaaa atatacatct accccaatct cagctagttt ttccgacaaa aactgggcat
     8941 tggtgttgac aatctgtcct gtcaaaatct ctgttccaac agcaatgatt tctgctttca
     9001 tgtttcctcc tacctatcta ttcgtatttt tttgaaaaaa tcgcaggaat tttcctacga
     9061 ttgatttttt tatttgtatc aaaagttaat tatcttcatc accaacaggt gctctgccaa
     9121 ataaatcttc aaataaaacc gcattggttt caagctgagt aacttcttct tgtcccaaag
     9181 aacgtcggag tatattttgc atttccaaca tatgtgctct cgaaacaatc tggtaagaaa
     9241 caccttgaag tatctctcct tcaccctgca actgctgagt ttcaatggtt ttaaatgaat
     9301 ctttatagcc tagcaagtta gggatacttt ttgcagacaa atcaatattg gtctgcatat
     9361 tgtcactcaa agcttttaga atctcttgat aatgaccaac gctatttaaa ctgagagctt
     9421 tttccatgac tttttgaata acttcacgtt gacgtttttg acgaccataa tccccctcag
     9481 gatcttggta acgcattcgt gcatagacta gggcttcttc tcccccaata tgttgctccc
     9541 caacaccgat agaaatagta ttaaattctt cttggtcact gatagaaatt gggaaaccta
     9601 ggatattatt gactgtaata cctcctactg catccactag tttttgcaac cctctcatat
     9661 tgaccatcac atagcgatca atatggatat tcatcatttt ttgaatggtt tctatagcaa
     9721 gctctgctcc accatctgca tatgctgagt tcagtttcgc ttcatgagcc tgaccattcc
     9781 ctgattcaat gcgcgtcaga atatcccgct ctaaactcat cattgttgtt tttttcgttt
     9841 taggattcac tgtcatcaag atcatgctat cacttctacc gacccaagtt tcagttcgtt
     9901 cagcatttcc ggtgtccact cccattaaca gaatggttag aggttcagtc gcttcaataa
     9961 ccttggtttc ttcgccgatt tttttatagg ttttagctaa ggtttctgtc ccttgttgat
    10021 aaatagtata agcaaaaaca cctactccta ctacagttac agaaagtaaa gctagcacca
    10081 ttccaataat ttttttaacc atatttctac taatctatca gtttacccat caagtaaaca
    10141 tcgataaatt tcccttcttc tatatatgcc ccacgctctt ggctaccttc aatgacaaag
    10201 ccatgctttt gataaagatg gactgctgct tgattacgag tttggacagt cagttggaga
    10261 cgacgcagaa tgccacttgc ttgtgcccac tctatcgctt cttctagcaa caaacttccc
    10321 aagccattat tccaatatct ttttccaatc acaatgaaga gatctccaat atgacggact
    10381 ctcttacgct ggtcagctgt aatatttaca ataccagcaa ttttgccatt taagaatgca
    10441 agtaaggtta tctgattgtc cgaactagct tgcttgttga ggaatatttc catctcctca
    10501 ctagtcaaga gaataccatc tccgtctagg ctggtaaagt ctgtctccaa actcacacga
    10561 tttaaaaagg ccactaattc agctgcatct ttgggctctg cttccctaat gagcaattca
    10621 tactccatat tgaagctcct ctaacaattt ctcagcacgc aaaccctttg cctgaaaatt
    10681 taaacggcgt ccatctgctt cttttagaat ttccaattct aaataagcat ctggcaaggc
    10741 atctcctaag agatttcccc actcaataac agtcacgccg ccaccaaaga taaactcatc
    10801 caagtcgata gaatcagcat ctccttcaat acgataaaca tctaggtgat aaagtggaag
    10861 tcgaccttca tactctctca cgatagtata ggtaggactt ttaatcattt gagaaatctg
    10921 taatcctttt gcaagtcctt tagtaaaggt cgttttacct gcacccagtt ctccaattaa
    10981 gattaaaaca tcattctttg ctaatagatg gcccaaacgc tcccctaagg cttgcaactc
    11041 ttcttcattt tttgtgtaca tactcttatt ataccaaaaa cttttctttt gtgtctattt
    11101 tcctactaaa cttatcatca taacatccat aaaaaacagg ctttctctaa aagaaaatga
    11161 gcgtaacaat gaccaataca agatctcgga aaatatgacc ataaaaggaa acttccttct
    11221 taaccgaatt tgggacaaga taggctgcaa aaaacaagcc cagtccagta taaatcagaa
    11281 gtgagacaat ggtcattgga tttcttaaga aaagaagtgt tgctaaaata gtcaccaaca
    11341 ctgtcttttt tctgtctagc atagcaagaa aatcgcgcac gtattttttc aagggtaaaa
    11401 aaatcagcaa atctagccca aataggaaaa agaaggatgg caataaaaag tcaactaatt
    11461 cttgctgcag cgtatttttg atgaacaagt tatctgacaa aacaagaaca gctcctaaca
    11521 aattaattaa gagtaacata ctgtaaaaaa gcttcaccga cttcttactg gctaggacac
    11581 tatggacttc ttgcttacgg gtataaagat aatttactcc agcacagatt cctgaaacga
    11641 aaaccatgct tccgatgaaa aaagctgtac tttgtttaaa ggacaagatg cattccttcc
    11701 ataggaaaca gctactcaaa ctgatttgaa ttaaagctaa caaaaataag attctcattg
    11761 atttcatctt ctctctccct tcctaccaat cattatacta ggagaaaaga gagaactgtt
    11821 tctaatcttc tcaaatgtct ctttaagacg ctaaacaaac actagagact aatactcaat
    11881 gaaaatcaaa gatcaaacta ggtagctagc cacaggttgc tcaaaacagt gttttgagat
    11941 tgcagataga gctgacgtgg tttgaagaga ttttcgaaga atataaattt gaaatcatga
    12001 aaatccgtca aacgggtggt tgttttgtct cgcacctcac ggagcgagac ggactcagag
    12061 tcacataatg ataaggctga tagtattaat ctaactatca gccttacagg ttatttaacg
    12121 tttcagaaaa actataatgt caagattaac taaacagtat ctaattcctt caaataattt
    12181 tctatcttca tcaacattaa aggattgtta taaatcttac ataactctct tgcttctata
    12241 taataatttt tgacttgttc tctgtctaga aatttggctc cagcatttcc tacaagaata
    12301 agtagaggag ccaattggta gcttgtctgt ctttgtttac agagttcaat cgtttcaaga
    12361 gcttcttgga tggcttcatt atatttttcc tttgatacta ggtagtgagc gtagttgtaa
    12421 cgaactctga tgtagccaaa taaaaactct tgatggtcca aattttttgt ctgatacaac
    12481 tctattaaat gagagtagtt tgcctcatat tcttgttcac gacccactaa ggaatagaaa
    12541 ttagatagag tattcaacgc ctttaaataa atcagagtat ttgaagagac ttttaataat
    12601 atattttcca atgaagaaat tgcctcacac ttactgtcat attgatagaa gtcaataata
    12661 gctttaatcc attcaagata agttcggtct tctagtgtta gaaaagtact tcgttcaatc
    12721 tcaattctat aaatatattc caaattatca taatttctgt catctaatag tcgagcagac
    12781 aattgcttga aattagagag gttagattta atttcaattt gttcattaaa aaaataatct
    12841 aatggtactt caagtcgttg tgagagtttg aacaaaaggt ctgcggaggg aatgaaatgc
    12901 cctctctcaa ttttactaat ctgactttgt tcacaaattc cttctgcaag agtttgttgg
    12961 gagagtctca actcttttct tttcaatctg aatttctctg cgagtgtatt cattaaagat
    13021 aataaacctt cctatttgct taatttcatt ataaaatttt tagttcaaaa tagtaagtta
    13081 aagaaacaaa taattcttta tggtaataaa taaaaaaagt caaaaattac ataaaaatac
    13141 ttgaccgaat aatatatata tgttaaaata aaaacaagga aaaagaaagg ggtttcacga
    13201 atgaagaaaa atcgtggaat tcaaaaatta gctatattag tattactagg tgtttttatg
    13261 tttagtaaca caattcctta ccaacagtta ttcagaagaa tagacaattg gagattcgag
    13321 tgcaatcaca aaagaagtcc aatggtcttg atgttgggaa ggctgattga tttcgtatta
    13381 ctttaaaatt caactattta gagaaaggta ttctgatgag agcttgtaac aataccagat
    13441 agatataaga atggagatgt ttgataaaat gctttcatag ctaaccaact gttgaaaatt
    13501 atgagttaca aaatctaaag tatttaagat tggtttataa aattaggtct ctgcctgtag
    13561 aaaggaacgt gcagttagaa aggaggaaaa aataggatac tataattcag actgagattt
    13621 ctaattaaaa tatgtagttg catttcgctc attttcataa tatttcattt agaggagtaa
    13681 taatatgtta aaatttagaa aagtagttgc atcatccctt gccgttttgg catttagttt
    13741 ggctcttcct gttttggcag tttctcaccg tggtggcgag tggacctatg gaggccatca
    13801 tgatccatat aattggggag cattttcgaa ttattatcat ggttcacagt atcactgggc
    13861 ctatgttgga agtaatgaac gtgacaatca aaaaacagtt tatgcaggag cacatagtgc
    13921 ggcctatgcg tttgttaata caaatttggg ggagcgaatt acatttgatg cgggatggta
    13981 aagaataatt gaagaagatt cttttatcaa tagtttagta agcttgttag tttatagagg
    14041 gcaggggtat ttctgccctc tgttttagaa taaggaatgc actatgaaaa aattatttat
    14101 actcatatcc aacctgcttg ctagtttgtt ctttgtttgg gtatttacca tttggactga
    14161 tacatatgtc tcccattatt accccaacgt tgttgtacat gattcttccc ctgaaacaac
    14221 ttttcagcat gttgctacac gcttggaaaa actagcagaa gaaacagata gctttattgc
    14281 gattcaacac caagatccta actcagaagg tactacagtt ttttcttata cgacctttgg
    14341 agacggaaag ttgcctgacg ggctacagga aaaaaaacta gaagatgctc aaagtagtag
    14401 tgttgaaaca aactattttg tattcgatgg acacctagat attcacttgc taagggagga
    14461 gctaagtcaa cttggcttga ctaatatgca cctgacaatt ccatctaaac tatctacgtt
    14521 aatggctatc tttagtaacg gatttcagtt aatcagtcta ttgattttca tcttaacctt
    14581 tggagcactg actttaatta gtcaaattag ccaattacgg tcgtcgggca ttcgcctcat
    14641 ttcaggagag aaacggtggt ccatttttct tagaccagtt ggtgaggatt tgaaagggat
    14701 agctgttggt ttcagtttag ctggcgtgct caccattctt atgcaaaaaa ttctgtcgct
    14761 tccaacgcaa tccctaatga ccataggagc aggcttgctc agttataatc tcatcttgtt
    14821 gtctatctcc ctgtttttcg ctcaactctt cgcagttggg ataaaaaaga tacacctgat
    14881 gcagattata aaagggcaag tgcctgtcag aggaatcatt agtttgattt taatcggtca
    14941 actattagcg attattattg taacactggg aatagggagt agcttaaagt attcccaagc
    15001 ctggcaacag catcggattg gacaagaggc ttggagccag gaaaggcaac tgattaccct
    15061 atcaatcagc cgtgaaggaa cgagtcctgg ttttgatgaa caagctcaaa ggaaactcag
    15121 aacttggtat caattgatgg atctggctgt ttcagaacaa aaggctttct tatctagaca
    15181 ccagttaatt gaccgtactt tgcaaaatgg catggcttcc tccaaaaact ttataacctc
    15241 tacagaatgg cacgattaca gcccgaatgg caatgtcctt atcgtcacac cgcaatactt
    15301 ggagcgtcaa aacattcctg tagatacaac tattgagcaa aagatgaatc accttgatgt
    15361 aggggagttt gtcttattgc tgcctgaaca cctccgttca gaggaagatc attataaatc
    15421 tgtttttgaa gacgacttaa ccagtcgcat gtctagtcaa gatgaacgac agcaaatgac
    15481 tgctacggta ggttatttag aatcaggtca ggatcgtttt gtgtataata cgacccctat
    15541 ttcttaccag cagtttttga aagatccaat catcattgtt ataacacccc aatcaactgg
    15601 tccacagtcc attttgtttt ggatagacgc agtacagaac tacgttctct ttaatcaatt
    15661 gtctgatgcc caggagctta tccagagaca aggcattgaa aattgggtct cagaaatgca
    15721 aacaggttac cacaactaca tcacattatt ggataatatc cagagggaac gttgggtaat
    15781 gctagcagga gctgtgcttg ggattgcaac ttcaatcttg ctgtttaaca ctatgaatag
    15841 gctctacttt gaagaattta gacgtgccat ttttatcaaa cgcattgcag gtctcaggtt
    15901 cttagaaatc catcgcactt atctctttgc tcaactgggt gtgtttttac tgggatttgt
    15961 tgctagtgta tttcttcagg tagaaatagg agttgctttc ttagtcttgt tactctttac
    16021 tggtctatct cttttacagt tacatgtcca aatgcagaaa gaaaacaaga tgtccatgct
    16081 tgttttgaag ggaggttaat atgattgaac ttaaacaggt gagtaaatct tttggagaac
    16141 gagagttatt ttcgaatctt tcaatgacat ttgaggctgg aaaagtctat gccttaattg
    16201 gttcaagtgg tagcggaaaa acaaccttga tgaacatgat tgggaaatta gaaccttatg
    16261 atgggacgat tttttaccga ggtaaagact tggccaatta taaatcgagt gattttttcc
    16321 gtcacgaatt gggctacctc ttccagaact ttggcttaat tgaaaaccaa agtattgaag
    16381 aaaaccttaa gctaggtctc attggtcaaa agttgagtcg gtcggaacag cggttgaggc
    16441 agaagcaggc tttagaacag gtcggcctgg cttatcttga cctagataag cgcatctttg
    16501 agttatcggg cggagaatcg caacgagttg ccttggcaaa aattatctta aagaatccac
    16561 cctttattct ggcagatgag ccaacagctt caatagaccc agcaacctct cagttgatta
    16621 tggagatttt gctatctctt cgagatgata ataggctaat cattatcgca acacataatc
    16681 cggcaatttg ggagatggct gatgaagtgt tcacgatgga tcatctgaaa taaaaatcct
    16741 tgtttttaat tgcacgatga gttactgaaa tattatcatg aatcaagaat tggagttaat
    16801 ttagaattgt actttattaa tattgaggta actttttctt gataaaggag gaaatagtgg
    16861 agaggaagtt agaatgaaaa aattcgacaa ttatattatt gagaagcctt gcgattctaa
    16921 ttcagataaa ctgcaaaaaa tcttaataat tgaaaatttg gtagatgata ttttgcaatt
    16981 tcctctcaga atcaataata gtgtaggaga gattttcctc ctacaaccgt ttcaaaagaa
    17041 aactatcttt attccatgtt attttgagga agatattgtg aaagtcaaag atgatgataa
    17101 agttgagtgg aatttgttag aatttcaaaa atttagagca tttttggctt agtaatctgt
    17161 gttgaaggct caaaacctat ggtaaaaaag tcgctttgaa aacgtattgc ctccaaagat
    17221 ttagttaaat aatgatttaa cacaaaaaga aattattgaa gttctggaaa gatgttgttt
    17281 cagtattgag aaaaggtggg aaaaacttgc gattttcaca gagaaaggaa gaaaaagtat
    17341 agaaatatag tcaattgaaa caagaacagg acaaaagaac cttttgtgcc atatttttct
    17401 cctttcgctt tacaattggc ttgaacacct ttattgtatc gcgtttggag tttttttggt
    17461 ataaccttcg acgcgcaccc gcatagcggg tgtttttttg tctcgcacct aacggagcga
    17521 gacgaactaa tagtcactta atcaaaaaaa cgcaccatat caaaaactaa aaagtttgat
    17581 atcatgcgtc atgtcttaaa ctaattgact atactttcta ttcaaatgag cttttaacca
    17641 attgattgag ccaatccact cttaaaacca aagagcaatt tctcgcttag ctgactcttc
    17701 tgaatctgaa ccatgtacaa cattttggat aacctcattt tctccagcag cttttgcaaa
    17761 gtcacctcga atagtgcctg gtaaagcttc ttctggacga gttgcaccca tcatggtccg
    17821 ccaagtttcg attactttgg gaccagaaat gacacccaca agaactggac ctgaagtcat
    17881 gaattcacga atcggtaggt aaaaactctg accaaccaag tcctgatagt gctggtcaat
    17941 caactcttct gaaacctgtg aacgaaactc caatttttcg attgtaaatc cacgttgttc
    18001 gatgcgcttt aacacttcac ccactagccc tctttttaca ccatctggtt tgatgataaa
    18061 gaatgtttgt tccatacccg tctcctttgt cagcttcttt cttttatttt accacatttc
    18121 gtggaaaaat ggagaaagtt ttcagaagag agaatgagag aacccgaggg ttctctcatt
    18181 ctctcttatt ctactgtttc ttccacagtt tcaacggcag tatccacaac tacttctgtt
    18241 gtttcttcat ttccttcttc ctctactgta ggattaaggt attcttcttc gttgacagca
    18301 tgtggttcaa ggttacggta acgggccata ccagtaccag ctgggatgat cttaccgatg
    18361 ataacatttt ctttaagtcc aaggagatgg tctttcttac cacggatagc tgcgtcagta
    18421 aggacacgag ttgtttcttg gaaggaagct gctgacaaga aactgtttgt ttcaagtgag
    18481 gctttggtaa ttcccataag gactgggcga cctgtcgctg gaactccacc tgcgataagg
    18541 acatctttgt tggcatctgt aaagtcattg atatccatga gggtacccat gagaagatct
    18601 gtatcacctg gatccatgac acggacttta cggatcattt gacgaaccat tacctcgatg
    18661 tgtttgtcac cgatttctac cccttggcta cggtaaactt tttgtacttc accgagaagg
    18721 tacgtttcaa ctgacaagac atcacgaact gcaaggagac gttttggttg gatagaacct
    18781 tctgtcagag cagcaccacg cgctacttgg cccccaactt cgacacgcat acgagctgta
    18841 aatggaacga catattcacc ttcgccagtt tcacccttaa caaagacttt cttggtacga
    18901 gttgatgcat cttcttcgat agcagtaact tgtcctttaa cctctgtgat aaccgcttcc
    18961 cctttaggat tacgggcttc aaagatttct tggacacgag gaagaccctg agtgatatcg
    19021 gtatttgagg caaccccacc tgtgtggaag gtacgcattg taagctgtgt accaggttcc
    19081 ccgatagatt gggcagcaat tgtaccaact gcttcaccaa cttcaaccgc atcaccagtc
    19141 gccaagttga taccgtaaca gtgacggcag acaccgtgac gagtgttaca tgtaaataca
    19201 gaacggatag tcacttcttc cacaccagca ttgacaattt cacgcgcctt gtcttctgta
    19261 atcaattcat ttggaccaat aatcactgca ccagtttctg gatgtttaac agttttctta
    19321 gtgtaacgac cgttgagacg ctcttcgaga gactcgatca tctcttttcc ttctgcgata
    19381 gaacggatca agagaccacg gtcagttcca cagtcgtcct cacggatgat aacgtcttgg
    19441 gcaacgtcga ccaaacgacg agtcaagtaa cctgagtcgg ctgtcttaag ggccgtatcg
    19501 gtcatacctt tacgagcacc gtgagttgag aagaacattt ccaataccga caaaccttcg
    19561 cggaagtttg aaaggattgg caattccatg atacgtccat tcggagcagc catcagacca
    19621 cgcataccgg caagctgtga gaagtttgag atgttaccac gggctccaga gtccatcatc
    19681 ataacgattg ggttcttagg atcttggtta gcaatcaagc gtttctcaag tttttcacgg
    19741 gcagcacgcc attcagctgt aacagcattg taacgctcgt cgtctgtgat cataccacga
    19801 cggaattgtt tggtgatttg ttcgacacgt ttgtgtgatt cttcaatgat ttcagtcttg
    19861 tcatcaacga ctgggatatc ggcaataccc actgtcaatc ctgcaagagt tgagtggtgg
    19921 taaccgaggt tcttcatgcg gtcaagtagg gcagaagttt ctgtcgtacg gaaacgtttg
    19981 aagatttcag cgatgatatt tccaaggttt ttcttcttga atggagggtt gagctcaaga
    20041 ttgctgatag cttccttgat atctccacca agtggcaaga agtatttagc tggaacacct
    20101 tctgtcaagt tggcattgtt tggttcttgc aagtatggta gcccctctgg catgatatcg
    20161 ttgaagagaa ttttaccaac tgttgtaagc aagaccttat gtctttgctc ttctgtccaa
    20221 ggcttgttga ggctgtctgt tgcgatacca acacgtgagt ggaggtgaac ataaccattg
    20281 cggtaagcca taaccgcttc gtcacggtct ttgaagacca ttccttcacc ttcgcgacca
    20341 gcttcttcca tggtcaagta gtagttaccc aaaaccatgt cctgagatgg agtaactacc
    20401 ggtttcccat ctttcgggtt caagatgtgc tcagcagcta gcatgaggat acgagcttct
    20461 gcttgtgctt cttctgaaag tggtacgtgg atggccattt ggtccccgtc aaagtcagca
    20521 ttgtaggctt cacagacaag tgggtgcaag cgaagagcct taccatcaat taagactggc
    20581 tcgaaggctt ggatacccaa acggtgaagg gtcggtgcgc ggttcaaaag cactgggtgt
    20641 tctttaatca cttcttcaag gatatcccag atacgctcat ctccgcgttc caccaagcgt
    20701 ttagctgctt tgacgttttg cacgatatca cgggcaacga tttcacgcat aacaaatggt
    20761 ttaaagagtt caatcgccat ttcacgtggc acaccacatt ggtacatctt aagagttgga
    20821 ccaacggcga taacggaacg tcctgagaag tcaacacgtt taccgagcaa gttttgacgg
    20881 aagcgtcctt gtttaccttt aagcatgtgg ctcaatgatt tcaatggacg gctacctggt
    20941 cctgtgattg gacgaccacg acgaccattg tcaatcaaag cgtcaactgc ttcttgaagc
    21001 atacgcttct cattttgaac gatgatacct ggtgcattta actcaagcaa acgagccaaa
    21061 cggttgttac ggttgataac acggcggtaa aggtcattca agtcagatga ggcaaaacgg
    21121 ccaccatcca actgcaacat tggacgaaga tctggtggga taaccggaag gatgttaaga
    21181 atcatccatt caggtttgtt tccagacttg taaaaggcat ccaaaacatc caaacgacgg
    21241 atggctttga cacgtttttg tccagtagct gttttcaatt cttctttgag ttcagcaatt
    21301 tctttttcaa gatctacttg cttcaaaagg tcttggatgg cttccgcacc catcttggca
    21361 acaaatgaac cataaccata ttcacgcaag cgctctcggt attcgcgctc tgtcatgata
    21421 gacttgtgct caagtggtgt atccttagga tcaatcacca cataagccgc aaagtagata
    21481 acttcctcga gggcacgagg gctcatatca agggtcaagc ccatacggct tggaatcccc
    21541 ttgaagtacc agatgtgaga tacaggagct ttcaattcga tatgtcccat acgctcacga
    21601 cgaactttcg tacgcgttac ttcaacccca cagcggtcac aaacaattcc tctgtaacga
    21661 atgcgtttgt acttaccaca agcacattcc cagtcttttg taggaccaaa gatcacttca
    21721 tcaaagagtc cttcacgttc tggtttcaag gtacggtaat tgattgtttc aggttttttg
    21781 acttctccat aagaccatga acggacttta cttggagaag ctagggtgat ttgcatactt
    21841 ttaaaacgat ttacatcaac cactatttct tccctttcta ttctaagtga actgcttatt
    21901 cttgttcagc agcttcttct gttgcttccg cttttgttgc tttctcagct tcttcagctt
    21961 caaaggctgc tttagcctct tgggctgctt tttcgcgggc tttttcaagg tcatctacgt
    22021 ggatgacatc ttcgtccatt ccttcatcca agtcgcgaag ttccacttct tggtcatctt
    22081 cgtctaggac acgcatgtca agaccaagag attgcaattc tttgacaaga actcggaagg
    22141 attctggaac acctggtttt ggaattggtt tgccttttgt aatagcttca taggctttca
    22201 aacgtccgtt gatatcgtca gacttgtaag tcaagatttc ttgaaggaca tttgacgcac
    22261 cgtaggcttc aagagcccaa acctccatct caccgaaacg ttgtccacca aactgagctt
    22321 tacctccgag tggttgttgg gtaacagttg agtaaggtcc gactgaacgc gcgtgcaatt
    22381 tatcgtcaac catgtggtgg agtttgatca tgtacatgac tccaacagaa acacggttat
    22441 caaatggttc accagtacgt ccatcgtaaa ggatcgtttt ggcatcgcta tccatacctg
    22501 cttctttaac agttgaccaa agatcttcag aacttgctcc atcaaagact ggtgtcgcaa
    22561 tgtgaatacc aagagtacga gctgccatac caaggtgaag ctccataacc tgaccgatat
    22621 tcatacgtga tggcacccca agtgggttca acatgatgtc gactggagtt ccgtctggaa
    22681 ggtaaggcat gtcttctaca ggaacgatac gagagacaac ccctttgttt ccgtgacgtc
    22741 cggccatttt atctccgacc ttaatcttac gtttttgagc gatgtaaaca cgaaccaaca
    22801 tgttaacacc tgattgcaac tcatctccat ttacacgtgt aaagatctta acatcacgaa
    22861 cgacaccatc ggcaccgtgt ggtacacgaa gagaagtatc acgcacttca cgagacttgt
    22921 ctccaaagat agcgtgcaag agacgttctt cagctgaaag atctttctca cccttaggtg
    22981 ttactttacc tacaagaata tcaccttctt taacctcagc accaatacgg ataatcccca
    23041 tttcgtcaag gtctttgagg gcatcttcac caacgtttgg aatttcgcga gtgatttctt
    23101 caggcccaag ctttgtatcg cgcgtttctg attcgtattc ttcaaggtga acagatgtgt
    23161 agacatcgtc cttcaccaag cgttcgctca tgataacggc atcctcgaag ttgtaacctt
    23221 cccaagtcat gtaggcaacg attgggtttt gtccaagcgc catttctcca ttttccatag
    23281 aaggtccgtc agcgatgaaa tcgccttttt caacgacatc accaactttt acgagagtgc
    23341 gttggttgta agcagtacct gagtttgaac gacggaattt ttggatgtgg taaacatcca
    23401 atgaaccatc ttcacgacga acttctacct tgtcagcatc tgcgtaagta actttaccat
    23461 catactgagc aatcacagcc gcaccagaat cgtgggctgc ttggtattcc ataccagtac
    23521 caacgtaagg tgcctgagga ttaatcaatg gcacagcctg acgttgcata ttggctccca
    23581 tgagggcacg gttggagtca tcgttttcca agaaaggaat acatgctgtc gcaacggcaa
    23641 ctacctgttt tggtgaaacg tccatgtagt caacaatatt agctggatac tcttggttga
    23701 ccccttggtg acgtcccatg acaatcttct cagcaaaggt tccatcttca ttcagacgag
    23761 agttagcctg agctacagta tattcatctt cttcatcagc tgtcaaccaa acaatttcgt
    23821 tcgtgacaac acctgtttca cggtcaacct tacggtatgg tgtttgaaca aaaccatatt
    23881 tgttcaagtg tccgtaagat gacaagttat tgatcaaacc gatgttaggt ccttcaggtg
    23941 tctcgattgg acacatacga ccatagtgag tgtagtgcac gtcacgtact tcatatccgg
    24001 cacggtcacg agtcaaacca ccaggtccta aggctgacaa acggcgtttg tgagacaact
    24061 cagaaagcgg gttgtgttgg tccatgaact gtgacaactg tgatgaacca aagaattctt
    24121 taactgcagc tgttacagga cggatattga taatttgttg tggtgtcaag acttcattgt
    24181 cctgaacaga catacgttca cggacattac gttccatacg agaaagtccc aaacgtactt
    24241 ggttggcaag caattcacca accgcacgga tacgacgatt tccaaggtgg tcgatatcat
    24301 ctacacggcc aagtccttca gccaagttga ggaagtagct catctcggca aggatatctg
    24361 caggagtcac cgtacgaacc ttgtcatctg ggttagcatt accaatgatc gttacgacgc
    24421 gatctggatc agttggagca acaaccttga atttttgaag aacaacaggc tcagtcacaa
    24481 cggctgcatc gtttgggatg tagacaatct tgttcaagtc gccatccaaa tggctttcaa
    24541 tgctttcaat cacgctacga gtcataatcg taccagcttc taccaagatt tctccagttt
    24601 cagggtctac caatggctct gcaatggttt ggttgagcaa acgtgtttta acattgagtt
    24661 ttttattgat tttgtaacga ccaactgctg ccaagtcata gcgacgtggg tcaaagaagc
    24721 gagccacaag caagctacgt gagctttcag ctgtcttagg ctcacctgga cgaaggcgtt
    24781 cgtaaatttc tttcaaggct tcgtctgtac gagagtccat tggattcttg tggatatctt
    24841 tttcaacagt gttgcgaacc aattcgctgt caccaaagat atcaaagatt tcatcatcac
    24901 ctgagaaacc aagagcacga accaaggttg taaatggaat cttacgagta cggtcgatac
    24961 gagtgtaggt gatatctttt gagtcgcttt caagttccaa ccaagctcca cggttaggga
    25021 taacagttga accatagccc accttaccat ttttgtctac tttgtcgtta aagtaaacac
    25081 ctggtgagcg gaccaactga gaaacgataa tacgttcacc accattgatg atgaaagtac
    25141 ccatttctgt catgattggg aaatcaccaa agaaaacttc ttgggtcttg atttcgcctg
    25201 tttctttatt gatcaaacgg aaggttacaa aaattggtgc tgagtagcta gcatcgtgga
    25261 tacgagcttc ttctagcgtg tattttggtt ccttgatttc atatccaaca aattccaact
    25321 ccattgtgtc tgtgaagttt gaaattggca atacatcttc aaacacttcc ttaagaccgt
    25381 ggtctaggaa agctttgaat gagtcagttt gaatttcaat caaatttggt aagtcaagaa
    25441 cttctttgat tcttgaaaaa ctacgacggg tacgatgttt cccgtattga acgtcatgtc
    25501 ctgccaagat gattctcctt tgtaaataag ttccaagcct tgtcaatcag gcttttctaa
    25561 tcgccatatg gttgtaaacc ccttatcacc gtgtcctctt gacgaatttt cagaatcttt
    25621 aagcctctgt tacaaatgct caaaatcttg aaaaaaagca caaaaagagc agctaaatct
    25681 gactttttca gaagatttaa ctgctgtgag ccttgtctgg acaatatttc agacaaaacc
    25741 tacgacaaat gattacccat attataccct atttagctag atttttcaag gggtttcagt
    25801 aggtttttgg taaatttttt cccatagaaa acttggcatc acattcgaat cacgctatgg
    25861 tacaaaaaac tgaaaaaact attgactgaa aatcattttc aaggtataat aataaacgtt
    25921 aaggcggtat agccaagtgg taaggcacgg ctctgcaaaa gcttgatcgt cggttcaaat
    25981 ccgtctaccg ccttctataa cttgatttat caggtttcaa atgaacagaa agcccaattt
    26041 gaagggcttt tcttattttc cctcgaataa atacgtataa ctttaaaaac ttttggagcg
    26101 agtttgtggc agagttcttt ccatggcata attccctttt gaaatcaatt gaaaaaagct
    26161 tcgtcacgcc tggtgacaaa agcctctagt ttattctgtt tcttcttcta tttcgacttc
    26221 tgtgatttgg atttttacct tggtaacacg tccattcttc actttatcat tggttaagat
    26281 aaactgtttg ttttggctga tcaattcata gctgagtttc tcagtcgttg gaatggttcc
    26341 cactcctgtc aaataataac cagcgatagt atcaacgtca tcactttcca gttcaacatt
    26401 aaagtaatta ttgaaatcat tgagggtcat agttccttga acaatgtagg tatcctcgcc
    26461 aatctgataa acatctattg ctgctttgtc cgtttcatca tcaatttcac caacaatttc
    26521 ctctaagagg tcttccaaag tcaccaaacc agccatacca ccgtattcat ccagcaagat
    26581 tgccatttgt ctttgggtat ttcgcagttc ttttagcaag tcatccacaa aaatagtttc
    26641 aggtacaaaa agtggatctt gtaaaattct cttccaaaca atattgtcaa aaccgtccac
    26701 aaagcctgcc ttaaggagac tcttggtgtg aatgattcca attacattgt ccttatcccc
    26761 atcataaacc gggatacgag aataattttg ttttaaaata ctttggataa tggcttgact
    26821 atcatcctga atatccacca taaaggcatc cgttcgagga accataacct ctcgtgccat
    26881 cagttcatcg agcgaaaaga caccttgtag catctcaatc tcatcagcat ccaatgtttc
    26941 ttcactattt gtcagcatat aggcaatttc atcacgggtc atcttttcat ccgcatcatc
    27001 gaatgacata ggagtcaaat ggctcaagaa attggtcgaa gcagctaaaa gccaaacaaa
    27061 aggactgact agttttccga tcccaatgat aaccggcgct gtacgaattg ccaaggcatc
    27121 ctttagatta agagcgattc tcttaggata taattcccca aaaacgatgg aaatataggt
    27181 caaaaatgcc aaggatagaa aagttgccac ggcttgtgct gtttcgccat tcccaagcca
    27241 agaggcaatc acacgtccta gagtatcagt taaactcgcc cctgataaga ttgtaatcag
    27301 ggtgattcct acctgaatgg ttgataaaaa gtggttagga ttttctagta ccttcagcag
    27361 gcggatgtag cgtctgtctc cttcttccgc cttttgttca actcgggcac gattaagaga
    27421 aaccatggcc atttctgtgg ctgagaaaaa ggcatttaat accgtcaaga taaacaataa
    27481 aacaaattgt agcaacaaat tctgactact tgggtcttcc atagttcttc tcctaaaata
    27541 gtatcttatc ctttattata tcacaaaatt taatccaata catattattt ttttcttagc
    27601 gtaacttcca tctctctccc aaaactggaa gttagtctaa gatggatttc cactgatttc
    27661 acgcgttttt ctcatactaa aagctaggtt gtgggaaact ggaagttagt tttagaagtt
    27721 gctatttttt cttagtacct gttctagccc tgcttaaact agtaaaaaga actcctacat
    27781 ccataagtga cataggagtt taggcttatc ttttactgag ttacagttac ttctccagtt
    27841 cggtaatcca gttgaagtcc cttttgaaca ttgggaacta gaacattgaa ttccaattct
    27901 ccatccgaag acttggcttc aatctgtgaa gctgagggaa ctaaatcctc gtttgaagcg
    27961 tagtaaaggg ttacacggta acggacacgc ttgttttggt ccaaggcttt acgcaccttg
    28021 ctttcatagt agttttgacc agtcgaatac tcggcttgtg cctgatttgc ccaggctgtc
    28081 tgaacagcaa tgtttttagg attgcttgtt gaggcatcaa aaccatccaa accaccgatt
    28141 aaggcatagc ctaacaaatg acctctatcg actgcatggg tataagagcc ctttagattc
    28201 ttgacctgat gccaacctgg aggagtccaa gaagttgaac cattcccagt ttctttacga
    28261 ttcttgtact gacgagtggc attagacaag agggcattag ctacggttgg aacagtttcc
    28321 ttgcccactg tctttgtttt attgtcagcg tagggcttac ttgaaacctt ggcatctaga
    28381 tttgttttat taccattgac gataaaagca cctgagccat tccactccag actccccttt
    28441 atttgactct tgactgcgtc tgttaagaca ctctctgcca atgcttgact aggagcttca
    28501 ggcgcttgtt ttttctgact aagattggtt ttgggactat taggtgccga ctgcatctgc
    28561 ttgatataat agctccctgt agacaaaagc aataacacta gcagtccgat tagtgtctgt
    28621 cttgtttttt tgttcatatt tctccttatc tttagaaaaa ggctggttct ccagcctaat
    28681 ttcctgtaaa tttatgaatc aattcctgcc attttgctgg agacaggata gcccatggat
    28741 cttgaccctt gcccaagatt ccataaccta ccattagacc gattcctaga gccagagtac
    28801 ctaaaatcag tactatgatg actaaaagta aacgcttgac tacgtagctt gatttcttat
    28861 tcatcttcat cacttgcctc aatccgctga atcttagcac ctagctgcgc caacttctca
    28921 tggaaaccgt agtaacctct atccaagtga accaatttac cgaccacagt ttctccctgt
    28981 gctaccaaac ctgtcaaaat caaagctgca ctggcacgaa ggtcagttga aagaacttct
    29041 gctccctgca aaggctgtcc accaacaata cgagctgtat cacggataat ctcagaatgc
    29101 aagcccatgc ggcgcatctc ttctaggtgt tggaaacgat tttcaaaaac tgtctccacc
    29161 atggttgatt cgccttttgc aactgtcatc aaggctgtaa attgagcctg catatctgtt
    29221 ggaaatcctg ggtggggcaa ggttttcaca tgaacagctt ttagattttc cagttgagaa
    29281 cgaacacgaa ttccttcgtc ttcttcaatt acttcaacac ccatttcaag taacttggca
    29341 atcaagggac ggttgtgctc ccagacagcg tctcgaatca agacatcacc accagtcatg
    29401 gcagcagcta ccataaaggt tcctgcttcg atacggtcct ggactacatt gtgagtcgta
    29461 ccatgaagtt tctcaacacc agtaatggtt atagtctctg taccagcacc tttgaccttg
    29521 gctcccattt cattaaggag aatggctaag tcaacaatct caggctcacg cgcagcattc
    29581 tcaatcactg tcaccccatc agccagagtc gctgccatca tcaagttctg cgttgcacca
    29641 acacttggaa agtccatata gatatgagca ccatgcaagc gttctgcctt ggcttcgatg
    29701 taaccagctg tctgactaat cttaaccccc atagcttcca gacctttcaa atgaagatca
    29761 ataggacggc taccaatcgt acaaccacct ggcatggata ccttggcatg acccacacgg
    29821 gcaaggattg gccctaatac aacgatggag gcgcgcatct tactgacata cttgtaaggg
    29881 gcttcctcag tgatgtcgcc agtagcatcc accttgacaa gatgagcttc ctcatcaaag
    29941 tcaaccttgg cattcaaacc accaactacc tgattcataa taaagacatc cgacaaaatc
    30001 ggaacattct gcaagacggt ctttccttca cttgctagaa tagtcgctgc caacaagggt
    30061 aagactgcat tttttgctcc ctcgatcgtc acgcttccta ccagacgatt atcgccacct
    30121 tgaaccacaa ttttatccat actcgtttcc tttactcttg attttataat aatcctctaa
    30181 gcgcttcttg ccacaaatga tacaggctaa taaagaaaga actcaggatg tagcctatga
    30241 caatgctaaa aaaggctact aatacacgaa cttttcttgt attctcagct gtcactttta
    30301 aaaccttttc ccatctaaca agatccttta aaaggtaaaa actcacataa ataaagagca
    30361 tatgactact tagagtgaat aataattgaa ccatttgact attataccat cttctctgtt
    30421 tgtgcgctag tttggaaact tcactcaaaa attagggatt gtttttcaag taatcaatcg
    30481 catcttgtag ggttttaacg ggcacgattt tcatatccgt cttgattgtt ttagccgctt
    30541 ctagggctgt ttggtagttg tttttcgcgt ccggatgcgc cttttgttct tcttcgctaa
    30601 cagggttatc aggagcaaag aaaatagcag cacctgccct agccgaagct acaaccttct
    30661 tatcaatacc tccaatgtct cccacattac catcgcggtc aatggtacct gtaccggcaa
    30721 caatacgacc attacgaaga tctgggtgag ctatttgagt atagatagct agactaaaca
    30781 tgagaccagc acttgggccg ccaataccag ctgttgaaaa gctaattggg acattgctga
    30841 ttacctctgt acgatcaatc aagccgattc caatcccatt ttttccattt tccaaggtga
    30901 taatctttcc ttctgcagac ttggtttgcc catcctcttc ataggtgacc ttgacggagt
    30961 cccctaattt ttgagaactg acgtaatcaa tcaagtcttt ggaactatca aaggtctgat
    31021 cattgactgc tgtgactgta tcagagatat tgagaatccc tttaaaggtt gaattatccg
    31081 tcacattcaa aacataaact ccaaagtact tgagttcgat atccttacca gctgttttta
    31141 gtccttgata cttggccata ttttgcgatg tttgcatgta gaattgattg attcgcataa
    31201 attcaacatc ggaagaacca cctgtagtct cctgagcact acgaatatct gtaaaaggtg
    31261 tcaaccaagc ataaatcata tgagctaaag tagcatgttg aacaccaacc gtaacgaatt
    31321 gataggcacc agcttcctta tcttctgtgt catttacttt aaggacttgg cgaatatctt
    31381 ccgaaccacc tggaacctct atatagtagg gcaaaggcac cacaaatgcc aagaaggtca
    31441 caatcaaggc cgcaatgaca tacaagggcc atctaatctt ttttttcatt tcttatttcc
    31501 tccaaaatac tctcgggaac atggcaggca atatcctgac caaacttcaa aagctctcga
    31561 acacctgatg aactgatata gagatgttca ggccggctat gtaaataaat agtctctata
    31621 tcagaagaca gctgatgatt gtagtaatca aaactagctt catattgcaa atccgccgca
    31681 ttcctcaacc cccgtactag gaaagtagcc cccagtcttt ttgcaacatc gaccaccaat
    31741 ttatcatgag aagccacgac ttcaacattt tccaaatgtc ccaaagcctt ttctagcccc
    31801 cgtttacgat tttcaagagg gagaaatcct tgtttgtggg gattaaaaaa aatacccaca
    31861 taaagcttat caaaaagtct gctcgcccgt tcaatgatat ccagatgccc atttgtcatc
    31921 ggatcaaatg agcctgtgaa taagccaatc ttatctgaca tagactgtca ccttactaat
    31981 tccataaatc ttttccttcc agatacccag acaggcaatt tcttctggaa gttcaacggc
    32041 tttatccgtc tcgcacacaa ccataacatc ttcagaaaaa agctctctct cagccatttt
    32101 ttcaatatct gctacgattt gttccttggc atagggaggg tctaagaaaa cgaggtcaaa
    32161 ttccccagat acctgttcca atgccctttc tgcatccatt ttgaggagtt gaaattttcc
    32221 aacttccttg gtcatctgga tattttcagc cacgatggtc tgagccttac ggtctcgctc
    32281 caccaaaaca gcactggaca tgccacgcga tactgcttcg atagataaac caccactacc
    32341 tgcataaagg tccaagactc gtcccccttc aaagtaggga ccaatcatgt taaaaatggc
    32401 tcccctaacc ttatccgaag taggtcttgt tgtcttgcct tctagtgtct taaggggacg
    32461 tcccccatag attcctgata tgattttcat actgtttatt ataccaaatt atagacaaaa
    32521 agagaaagaa aaccgaacct tgcggttcga ttctctacaa aatattttcg taagtatcgc
    32581 ggacttcttg aggccaaaca cttgtttgca cttctccgat gtgtctcttg cgaagtagga
    32641 acatggccat acgagattgt ccaattcctc caccgattgt caatgggaat aggccattca
    32701 acaaagactt gtgccattcc aattccaagc ggtcttcatc acctgtaatt tccacctgac
    32761 gtctaagagt ttcttcatct acacgaattc ccatagaaga caactcaaag gctccaccta
    32821 aagactcatt ccagacaaga atatcaccat ttagaccctt gtagccattc tcagactcgc
    32881 ttgtccagtc atcatagtct ggtgcacgtc catcgtgcgg tttaccatct ggcaactcgc
    32941 caccgatacc aatcaaaaag acggctccaa attctttaca aatcgcattt tcacgttctt
    33001 tcggtgtcaa gtctgggtag cgttctacca attcttctgt atggataaag gtgatttgtt
    33061 ttggcaagat agactcgatg tcatagcggg cttcaacagc tagctcagtc aggcgaatag
    33121 ccttataaat cttctcaact gtttctttta gataaacgat gttacgctta ccatttggga
    33181 taaccttctc ccagtcccac tggtcaacat aaacagagtg ggttgcatcc aaggaatcct
    33241 catctggacg aagggctttc atgtggacaa agagaccctc tccttcacca aagccaaaac
    33301 gagccaaggt gtggcgtttc catttagcaa gtgagtgcac cacttcataa gtagcatcag
    33361 ggatttggag aaccttgacc gatactggat tttccacacc agacaggttg tcctgcattc
    33421 cgtcaccgac cttactcaag ataggacctt gaacttcgac aacttctagc ttatctttca
    33481 aatactgggt aaaagtgttt ttgacaaagg aaatttcttc ttgttgatgg ataaaacttt
    33541 tcttcataga caactcctca aaaatttaat aaacgtatta tacacctatt tccaagaaaa
    33601 gaaaagagaa aatttaaaaa aaaatcagtg tcactcaaaa cactgatttc atagaccttt
    33661 tagtcattgc gaccaaagat acgtagaata cttaggaaaa gattgataaa atcaagatag
    33721 atgctgagag ccattgacac cacccagcct gtcgctacac gaccttgtga ttgttcatag
    33781 gcgaggcgaa tcttttggtt atcccaagca atcaaccctg aaaaaaccaa aaccatggct
    33841 acgctaatca tataatcaaa gaagccacta gccaagaaaa tattgactac catagcaatc
    33901 agtaaaccaa tgagagctgc catcattgct cgaccaatcc cactcaagtc tttcttggta
    33961 aagataccaa ctgccgccat gacaaagaag agaagggcgc tcgatacaaa ggcagataaa
    34021 actgtacccg gagtatagaa agccaccaca aaactaaggg taaagccgtt taaaacggag
    34081 taaagtaaaa atactggaag agcagctgga ctatttcttg aagccatact actggcaacg
    34141 aaaaccaaag ccaactccgc aaaagtagca atggtcaacc agagacgccc ctgcatcaac
    34201 aagtaaacca actgagactg aaagaccgtc aacataaggc ctgataccaa agcagatagt
    34261 ccgattccca gaccaacaaa ggcataaacc ttagcgtaaa attgattgag acctgcacgg
    34321 tcatgtataa tagtgtgatt catccttttc tccttttctg tgaacatctt tccttgatta
    34381 taacaaaaaa agttaaaatt agcttaaatg gaagattaaa ataccggctg caactgcaac
    34441 attcaaactc tcggcctgcc ccttcatgct aatatggacc aactggtctg cactttcagc
    34501 cataagggga ctaattcctt gaccctcatt tcccataact agtacaaaat tttctataga
    34561 aggcagttct ctgtaatcaa cagaatcttt agatagggtt gttgctagca ctgggatagc
    34621 taccttttta gtttcgtcaa gaagcgcttg actagtcatc cggtaaatgg gcagatggaa
    34681 atgactacct tgcatggaac gtagggtttt gagactgtag atgtctgccg acttatctga
    34741 aacaatcact cctgtaaaac ctgctgcatc cgcagttcga atgatagttc ctacattacc
    34801 aggatcttgc acatcttcca aaaacaagaa cttgccctga ctcaaatcag cttgtcctac
    34861 ttcttctttt tgaaccaccg ccacaattcc ctgtggagtc tgagaatccg ccaaatctag
    34921 caaaatatcc tctgaaatcc agacagtttg cggaaaagca gctaactgat ctcgataatt
    34981 ttctagggca aagattttct caatcgtcac tccagcttgg acagcctctt caaacaagtg
    35041 ccagccttca atcaaatagg cagacttgcg gtattttttt tggtgtaatt tcttggcatt
    35101 ttttaccaca gaattggctt ttgaggttat aatagtcata gaaatattat aacacaatca
    35161 aaggggtttg gtatgcaaaa ggttagaatg attgcccaag gtagggtaca gggagtcggc
    35221 tttcgttggg gtgtttacag cttggcactt gaaattggtg gcatcacagg tcgagtatgg
    35281 aataacgacg atggcacagt ggaaatctta gcccaagcag actcatctgc tatcatggca
    35341 aaatttatcc aagaaatccg aaaaggaccg acaccttttt caaaagtaag ctacttagat
    35401 gtcaaactaa gcaactttcc tccctactct gactttaaaa tcgcaaatta ggtctccaga
    35461 actattgtat attttgtaaa aaaacagtag aatagaaagg tataattttt aaagaaggaa
    35521 taaaaacagt gaaatctatt aaacgttttg cattctcggc tatgggagtg gctatgttgc
    35581 ttgtcttgac tggctgtgtc aatgtcgata aaaccacagg tcagccaaca ggatttattt
    35641 ggaataccat cggagcgcct atggctgaag ccatcaagta cttcgctact gataaaggtc
    35701 taggctttgg tgtcgctatc attatcgtaa ccattatcgt acgcttgatt atcttaccac
    35761 ttggtatcta ccaatcatgg aaggcaacgc ttcactctga aaagatgaac gccctcaagc
    35821 acgtccttga gccacaccaa acgcgtctca aagaagcgac tactcaagaa gaaaaactcg
    35881 aagcccaaca agctctcttt gctgctcaaa aagagcacgg tatcagcatg tttggcggtg
    35941 taggatgttt ccctctcctc cttcaaatgc ctttcttctc tgctatctac tttgctgccc
    36001 aacatactga aggggttgct caagcaagct acctaggcat tcctctaggt tctccaagta
    36061 tgattttggt tgcctgtgct ggtgtccttt actatcttca atcgctcctt tcacttcacg
    36121 gagtagaaga tgaaatgcaa agagaacaaa tcaagaaaat gatttacatg agcccactca
    36181 tgatcgtcgt cttctccctc ttctcaccag ctagtgtcac actttactgg gttgtcggtg
    36241 gtttcatgat gattctccaa cagtttatcg tcaactatat cgttcgtcca aaacttcgca
    36301 aaaaagtccg tgaagaactg gcaaagaacc caccaaaagc aagtgctttc tcaacaccaa
    36361 gtggacgaaa agacgttacc cctgaacaac caactgctat tacaagcaag aaaaaacaca
    36421 aaaatcgcaa cgctggaaaa caacgttcga gataagaaga aaaaggctta gctgatttgc
    36481 taagtctttt tgcaagtcaa aagcccgatg tttccatcag gcttcttttc tatccatgta
    36541 cacgtttcat ataatcttga taactttcgg tatccatgag ttgtttagcg ttcttgacgc
    36601 gatctgctgt tggtggtttg actccttcga gggaatatgg aattccaagt tcacgccact
    36661 tgaactcacc catggtgtga taaggtagaa tttcaaactt atcaacattt ttgagggtct
    36721 tgacgaactt accaagttca atcaagtcat catctctgtc tgtcaatcct ggaactagca
    36781 cgtggcgaat ccagacaggt tttccaatat ctgatagata ctgggcacaa gccaagatat
    36841 ttttattggt ttggctagtg acaatcttgt gctgttcttc gttgatttcc ttgatatcca
    36901 aaagaaccaa gtcagtgaca gccatgagtt tgtcaaactt ctcaaggtaa cgtggtttat
    36961 tacggaaagg aagagcacaa gtgtccaagg tacagtggat tccttgttcc ttagccttgg
    37021 tgaagagggc aatcaggaaa tcaatctgca agagagcttc tcctccactg actgtaatcc
    37081 cacccttatt tccccagaaa ccacggtagc gcaaggcctc tgtcaagaca tcatctaccg
    37141 tccgttcacg tgacttattg gactccatag cccaagtgtc tgggttgtgg caatactggc
    37201 aacgcatgtg acagccctgc aaaaagacaa taaagcgaat accgggccca tctactgacc
    37261 caaagctttc tgtcgaatgc accattcctg tcacttgtcc ataatcaatt gtttcttcag
    37321 acatatcgtt accttccttg aaaacgtttt atagttttat tatatcacga cttgaaggaa
    37381 aaacaagatt tttgcctatt ttttagaaag caatctgttt ttcaatttca ttttcaatct
    37441 attatcagat tattcttcaa aatcgaagcc atataaggtt gcaaaatagt cctcagggcg
    37501 ctctgcacgg cggatttgac gggctttacc ttcttcggta tagaggattt ccgcagaacg
    37561 taatttggca ttatactggt agcccattga aaatccgtgg gcacctgtat catgaattac
    37621 cagcaaatca ccgatttctg tatgaggcag ttcgcgattg actgcaaatt tatcattgtt
    37681 ttcacagagt gaaccaacca catctaccgc ttcagctggt ccatctggat gggtcacgtt
    37741 gctaatatga tggtaagctc cgtacatagc tggacgcatg aggttgactg ctgaggcatc
    37801 tacacctaga taggtacggt aggtttcctt cttatgagtg actcttgtga ctagagcacc
    37861 gtgaggtgcc agcataaaac gacccaattc ggtgaaaatc ttgacctgac caagacctgc
    37921 tgacgtaaga acttcttcat acaccttacg aactccctca ccaatcaagg cgatatcgtt
    37981 cggctcctgg tctggacgat aattaacacc aataccgcca gaaagattga taaagtctaa
    38041 cgaaatgccc aacttttcct tgatttcaac agccagttca aagagctgac gagccaactc
    38101 tggataatag agatgggtca cggtattgga cgctaggaag gagtgaagcc caaaagtctt
    38161 ggctcctttt tccttcaaga tagcaaaggc ttcaaagagc tggtccttgg tcatgccaaa
    38221 cttagcctcc ccaggattgt ccataatgtc tgtccccagt tcaaaaacgc ctccaggatt
    38281 ataacgacaa gagatgattt ctggaatgcc tgctactctc tccagatgtt caatatcttc
    38341 aaaggcatcc aagttaatgg tcgcacccaa ttcacgtgca taggcgtatt ccttgtctgg
    38401 cgtgttgttg gaagagaaca taatctcaga acccagaaag tccagtttat ggctcatcaa
    38461 aagctctaca taactagagc agtccacacc acaaccttct tcttggagaa ttttcaaaat
    38521 agctggagtt ggagtagcct taactgcaaa atattcctta aagcccttgt tccacgaaaa
    38581 agcttggttg acagctcttg ccttctcacg aatccccttc tcatcataca agtgaaaggg
    38641 agtcgggaac tcggcaacaa tcgcttctaa ctcttctcta ttgataaatg gtgttttcat
    38701 aagcttcctt ctattctgtt tgcaaagaaa ggctgggaca atcgttccaa cctttagttc
    38761 tatctcttat ttatcttcgt caaagatatt gccaacctca acatcgatgg cttggttctt
    38821 gacatcaata ttagttacct tcaagagtga cttgtagtca aactgctttt cacgttcttc
    38881 ttgggcattg tccgcaaaga ccgctacacc tgccagttct gagtcgaact cgcgcaagag
    38941 actaatcata ccgttgaccg ttccgccacc tttcaagaag tcatccacaa tcaagacacg
    39001 gctgcctgcc ttaagactac gttttgaaag gaacattttc tcgatacggt caccacttga
    39061 acctgaaaca tagttgacgc taacagttga accttcggta attttcaggt cacggcgcac
    39121 aatgacaaaa gagacattga ggacattggc aactgcattt gcaagtggca cacccttagt
    39181 tgctacggtc ataaccgcgt caattttttg gtccataaag cttttggcaa taatacgacc
    39241 aatatttttc aagatggctg gtgtgctaag caaatcagac agatagatat aaccacctgg
    39301 caagatacgg tcactttctg acaacttggt acgcaagtct tcaaccattt ccttagcatc
    39361 ctgactcgaa atagacggtg tgaagatgac acctccgcca gccccagtca ctgtctggat
    39421 atgaccgatt tcaatttcct caaaggcgcg tttgataatg acgatatctt ctgagatgga
    39481 tgatttagca gactcatact tttcagcaaa agtattgaga ctagttagtt tataaggatt
    39541 attaatcaaa tagttggaaa tgacaaccat ccgatcactt cttcttaatt tcatttctat
    39601 ttcctattcc atttttattc aaaaaatcaa aaagcaaact agaaagctgg tcgctggtgg
    39661 ttcaaaacac tgttttgaga ttgtcaatag aactgacaaa ccctgtaata tacctgcata
    39721 tatacatacg acaaggcgat actaccctag tttgaagaga ttttcgaaga gtattcattt
    39781 ttgtctttta cttattatac catattcaca taaaaaaacg aacattctta tcctaaaaaa
    39841 tgctcatttt tcttaaatta ttaatctaaa tctggtttat agaaggaacg attatccata
    39901 gcgaagattt tattggtcat ctctccttta tccaccaaag caagagctgt tgacatcatc
    39961 atcatgcttg catccagatt gtcaatcata tggataatct ctgcttccat aatgcgtgga
    40021 cggactgggc ttccatactc aagcaagccg tggtgactga ggatgacatg acgaagcaaa
    40081 acgacttctt ccttggtatc atcgatgccg agttccataa ctgtcttggt aatttcgcta
    40141 tcaatgagag cgatatgtcc aagaagatta cctcgcactg tgtactctgt ctggtctggc
    40201 cccgtcaact cgatgacctt agctaagtca tgcaacataa tccccgcata gagcaggctc
    40261 ttattgagct gaggataaac ttcgctaata gcgtctgcca aacgcaccat ggtcgccgta
    40321 tgataggcca agcccgtttc aaaggcatgg tggttggtct tggcagctgg ataggagtag
    40381 aattccttat catacttggt gtagagattt cggacaatcc gttgccagac aggattttca
    40441 attttgaaaa tcatttgcga catgtagtca cgaatttcct tgacatcaac tggtgacttg
    40501 accttgaaat cagctgggtc attgggttca ccagcttgag gcaggcggag agtaatttga
    40561 ttgacttgag gggtattgtt ataaacttct cggcgtcctt tcatgtggac aaccttacct
    40621 gcggtaaagg cctcaatgtt atgaggttgg gcatcccaga gcttcccatc aatctcgcca
    40681 ctatcatctt ggaaggtaaa ggctaggtag tttttcccag ctcgagtttg cctcaggtca
    40741 gctgatttga ttaggtaaaa gccttcaaat aactcatctt ttttcatgtg actaatcttc
    40801 atattcttcc tcattttctt gaaaatggag tagatcaagc gcaggctcac cttctgacaa
    40861 ctcaatgtga cggagcgtcc gctcgatagc tatggtacga cggtttaata attcatcaat
    40921 attgccagag gcatgttgga gatgtttttg tgccttgacc agaataccac caaacttgcc
    40981 aaactcggtc ttgacactgg caagagtctt gctgatatgg tcggcactct tttggatatt
    41041 aagggtcttg aaaccaactg atagggagtt aagaagggct gatagggtac ttggtcctgc
    41101 aacaataatc tgttcttccc gtctcaaatc atcaaagaag accggattgc ggacgatttc
    41161 tgagtagaga ccttctgtcg gaacaaacaa aactccaaaa ttggtcgtcc gaggtggtgc
    41221 tatgtacttg ttcctaatat ccctagcaaa gcgcttgacg cttgctagga gtgacttacg
    41281 acagcgttca atctcatcct tgtcacctgt ctcataggct tcttccaagc ggtaataatc
    41341 tgccagtgga aacttagagt caattggcag atagacgtat tcttggtcgc cttgtccggg
    41401 taacttgatg gcatactcca ctcgttcact agagttttca accgttgcgt attctcgttc
    41461 gtactgggca ggtgtcatga tgtcttcaat aatttgcccc agttgcaatt ctcccagaat
    41521 ccctcgcgtc ttggttccag agagaacctt gttaagagct ccgacatcac gggcaactgt
    41581 ctgcatttct ccaaggccac gattgacaga ctccagttgt ttagaaactg tctcaaagga
    41641 agcctgtaag cgtgtctgca aggtcttttc tagtttttcc tcgaccgtct ggcgcatttg
    41701 ttccaaacgt tgctcatttg attcctgcaa ggcttggaga cgttggtctg tcttgtctct
    41761 agtttggagg agattatctg tcatttcttg acggacttgg gtcagacctt ggtgcaattc
    41821 aatccgcact tcttgcaaac ggtcgctgac aaccacttcc aaatcttttt ggtctaactg
    41881 gctggcttgt ctggcttggt caaagcggta atccaactgg tctgacaaat gatctgcctg
    41941 atcctccaag ctcttactta agtgtttctc ctgcctatcc tgcctttgcc aaatcagaaa
    42001 gagaccagct agattggcaa ttaataatag aataagtaaa ctttccatcc tacctcctgt
    42061 ccttgctatg cagtacgacc acataaccat ctgggcaagt taccgacact tccctatcta
    42121 tatattcgtt agaagcgtac acttttttaa agaaaaaatt ttcctctgtc aactcatact
    42181 tggctccaag aatagtcagc tggctatccc gaactggcat aaaggctaga tagtcgtagt
    42241 ctgaacgagg ttctagctga ctgattcctt ctggacaata agtaatcaag ttttgcccat
    42301 cctcaatttc tatttgatgc atatagggtg ccaacttagg attgctaggc agaaagacat
    42361 tggccaacat atggtcaata cggccaccca aggcaccgaa aatagtgacc tgagcctgag
    42421 gattttgttc aaagatggtt aagagagcca attccagatc tgtatcatcc ttttctggtc
    42481 gtgcttggac aaaatactgg gcaccttttt gaatcacctg tcgctcttct tccgtcacag
    42541 aatcaaaatc tccgactgct agagcaagag gtaagtcttc ttccaagacc cagagcgagc
    42601 ctcgatccac cccaacaaaa gcatcaaaat ctgtccgata atgaccgcgg tttccgcctg
    42661 caaaaactgc aaccctagtc cagttgtttt ctgagagttt gtactcgctc attgacttct
    42721 cccttaaaga cataggaacc tgctacaaaa acagtcgcac cggcttcttt ggcttgagca
    42781 atagtttggt catcaatccc accatccact tcgatttcaa agttcaaacc tttttcctca
    42841 cgaagagcaa ccaactcacg gaccttatcc atggtttctg gcagaaaggc ttgcccacca
    42901 aaacctggat taaccgtcat gactaaaact tggtcaacta gatgaaggac gtgcttgatg
    42961 gcttcaactg atgtgccagg attgataacg actgaaggct taactccgag tgaacgaatt
    43021 ttttggaggg cgccatgaat atgaggcgtt gcttctacat ggatactgat gatgtctgca
    43081 cctgcacgcg caaaatcttc cagatgatgc tcagggtttg acaccatcaa gtggcaatcg
    43141 aaaaccatct tactatgagg acgaaggctc tcgaccacac ctgcaccaaa actgatttgc
    43201 ggtacaaaat gactgtccat gatatcgata tgggcatatt ctgccccagt tgcttctaga
    43261 cgtttgattt cacgttcaaa gttggcataa tctgctgcca gaattgacgg agcaatcttg
    43321 tattgagaca taggtttctc cttattttgg aatttttttg ctgacttttt tataggtttc
    43381 tctacgattt tcaatttcac taaggaattg caggtaattg tcaaaacgga aggttgcaat
    43441 aacaccctct tcaacagctg gtttgacggc acaagacggc tcatgggtat gggtacaagt
    43501 acggaactta caatctcggc taacagtagc aatctctggg aaagcctgat tgaggtcttc
    43561 agcccttgat acttcatagt ccaaggatga aaatcctggt gtatctgcga ttttaccccc
    43621 gttgagattg taaaaactaa cagctcgagt ggtatggcga ccgcgaccta gactgtctga
    43681 aatttctccc gtttcaagat tgaggtctgg tgcgatttta ttgagaagag ttgacttccc
    43741 aacacctgtc tgccccataa agaccgtaac cttgcctgtt aacaaagaca ggagttcctc
    43801 tttactggtc acaaagtcat agccgatgtc accataggtc tgctggtaaa aatccagttc
    43861 tcccctatct tccaacaaat ccattttgga aatatagaca atgggatgga tgcccttgtg
    43921 ctccaaaaga accaagaaac gatccagcaa attgctgtta aaatcaggtt ccttgacgga
    43981 catgattact acagcttgat cgatattgac aataggcgga cgaaccagac tgtttttccg
    44041 ttcgtgaatt ttgaggatat agccttctga attttcctcg gcagagaaat ctacccagtc
    44101 cccaacataa ggggtatggc cttttttacg gaaattccca cgcgcgcgtg tttgataaac
    44161 ctggccatca ctctccacat agtagaaacc tgccaaggct ttaatgattt gtccctgcat
    44221 cttagagtcc ttgcccttta agtgcgtctg ctagaccggc aaattctgcc aagctgagag
    44281 cttccccacg cacacttggt gacaagcctg cctggtccaa agccttggtc agcttgtcct
    44341 tgacctcttc agtcttacca aagtaacctg tcaagttatt ccacaaggtc ttgcggcgat
    44401 gggtaaaact agccttggaa accttaaaga aaaagttctc atcttctact gctacggctg
    44461 gctctggacg acgcaccatt ttcaagatgg ctgaatccac atttggcgct ggcacaaaga
    44521 ccgtacgagg cacgataaag gcaaccttgg ctgtcatgta atactgcacg gcgatagaca
    44581 agctaccgta agccttggtg ttaggctggg ctgaaatgcg gtccgctact tctttctgca
    44641 tcatgaccac aaactcacaa aaaggaatgc cactctcaat caagtgcatg agaataggcg
    44701 tcgtgatgta gtaaggcaaa ttagccacta ccttgattgg caggtcagga tttttaaaat
    44761 tctggatatg ttgcgccaaa tcaaccttga gaatatcttc gttaactacg gtcacattat
    44821 caaaatcacg cagggtatct gccaaaattg gcaccaaacg gtggtcaatc tcaaaagcca
    44881 tgacttgggc tgcacgctca gccaaaaatt ctgtcaaggc accaatacct ggcccgattt
    44941 cgatgacatt gacctgatca tcaatttcag ccgtatccac aattttttga aggatattgg
    45001 tatccgtcaa aaaattttgc ccaaaggact ttttaaaggt aaaaccgtga cgctccagca
    45061 ctgccttggt cacgctataa tctgcaattc tcatctattc tcttttctat tatctgttac
    45121 tactattgta acacattccc cttgtatttt gggaatgaaa atcataccaa aaaactatct
    45181 ttcctcatga agaaagatag tcttggaaat ctttaaaagt ggccttagca gttctctcga
    45241 aacatgcgtt caaaaaaatc agcttcttga taacttcgat tttcaggtag ggtcaaatcc
    45301 acatcctcct ccacatcatc cactgtcagt tcaaccgtct gaggtaaatt tttcaaacga
    45361 taatgctttt gcctttgccc ttcaatacta gcaaaatcaa gcaaatagcc atgcactcgg
    45421 atttgaacca aaaggagatg attggtcata ttttccatga tgaggatatc ttctaaacca
    45481 cctctggcac taggataatc agataccctg cgaatacgga ttttttcaca catgagcaag
    45541 tttcctcata tcaatgattt catcagcctt attccagact aggggattat gggtcgcaat
    45601 gatgataatt cgattttcat ctttcaaatc caccaagaga ttcataacct cctctgaatt
    45661 ttcaggatca agagctgctg ttggttcatc tgccaaaatc aagggtggat ttttcaaaat
    45721 agtcttagca agggcaactc gttgggcctc tcccccagat aaagtataga ttttttgttc
    45781 taaatccaaa taccctagat taactttttc taaagccccc acttgccttt ccaaacgttc
    45841 tacttttgag attttctgac caacaaaacc caaatccaaa ttttctttga ttgattggtt
    45901 ttctaagagg ccgaaatttt gaaagagata gcccatctgg tctcgaaaat actcacgagt
    45961 gggaatggtt tttaaatctt tcccctgata gagaaccctt ccaccatcta tcttttctag
    46021 ctttcccaag atattcagca gcgtcgtctt tccgcttcca ctctttccga ttaaggcata
    46081 aaccttgccc ttctccagct tgagattcaa accagagaaa atcgcgcggt cattaaattt
    46141 cttttccaat ccttgaatat caatcatctt attttccttt caatactgcc atgctaccag
    46201 cttcttcttt tttgtcctgc cttactaaaa tcaagagggc gttaagcgta aacaaagcta
    46261 caactagagc gctaatcaaa ccatctcttg tcaaaatact agataggact aggccaagca
    46321 agagaactcc tccttgcgcc agtaaatact tgccatgaag ctcatagatt gtcataccag
    46381 caagacgttt aatcataagt tcccgtctga actgctcaaa atagagaaga ttcatggaat
    46441 caaataacaa gatagccgta gacagggtca aaatcgtccc aataaggaga gagtaaaact
    46501 ccacccgttt gtcatttagt accttggcaa aaaatagctg gctttttacc aagtaagaaa
    46561 ccttgtgata cagacctttc tcttttagag ctgtgatgct gtctccatat cgatctagtt
    46621 tcaaggcact attagccgta gttccccaca acatccctgc aacaggtctt gttccagtcg
    46681 cttgcggcgt tagaactaca ataatcggat cttttaggta ctggcgtgtt gtcttgtacc
    46741 catcattata gaggaaacgt tcctgtcctg tttctgtaaa agctagcctt acctgtggga
    46801 ggtagtgttt ctgactcgtc acttctacac tttcagatga aaagttttgc aggtaatctg
    46861 taaacaatcc ttggtagtag acagactgct ctcgcaagct ctcaggcaag atcagcccaa
    46921 actctccctc agacaagttt tgcatcttgt ccataaactc tgaagaaacg gtaatctttt
    46981 cttctatcag atagcgcggt gagacataga taacattccc tgacggtgtg tagtcactga
    47041 gacgattgcc atctaggtcc acttctgctc catctgagaa attgtcaaca ttgctcataa
    47101 tataaaaaga gtctgtattg gctaaccgtt cttcagtaaa tgtctgccac tcacgattat
    47161 ccttacgcgt tccttcttca tcggcaaatg cactagacca accaaaggat agacggtaac
    47221 ggtctgagga ctggctccat ttattgctag ctctctccat ttcctgcatt tcacggtagt
    47281 ggggtaggag agctgtcgca ctcgatccga ccaccaatac agctaagagt tgccccacca
    47341 tcatcaatgt catcatacgt ttgagaggga gtttcccttt caatagatcc accagactat
    47401 tttcctgtaa accaagtaga tagacgacac ttagtaaggt agaaatccct gccaaggtca
    47461 atccataaag tagaagagca atgatgacca gttgcaccgt tgccataaac aaggcacctt
    47521 gataccagag aatccccaat cccaaaaggc tggataccag cactgagcag ataagctgtc
    47581 tcacatcttc taacactggt ctgagagcaa ctccaaacaa gctctcacca gctattaagc
    47641 gaatccctgc ctgacgaagg gatttgatcc gataaatcag ggtcagactc ataaaggtca
    47701 gcagaaaaat agctaaactc agtagcacca taggggtggc cgtcaatagt aagactatcg
    47761 aaaatggatc ttctccattc gaaacaaagc cttgataacc aagctctttc aaggtggtct
    47821 gtaagctcac tccatccaaa cttcctgata caatcaagta agaccctaat aaatcactcg
    47881 tttctgcact ctccttggag gaaatggtca gaccttctgg aagctttccc tcaccataag
    47941 tggcataggt aaagcgtgtt tctccagctt catttggctc aacgattcga cgagcaatga
    48001 gactattgtg ctctaccgcc aagtgactca aagcctctgt cacctcttcg cgactagcta
    48061 ctggttgatt tatcatcatt cctgtcacat caacagaagg atagttacca aataaaatct
    48121 cttctcgatg gtcaacggaa gttatcacca tataaagcga tactaatacc attgaaatca
    48181 aaataaataa acgtttcatc atttcctcca aaaagttact tggtcacttc gtgagaaggt
    48241 gaccacagtc actgcgatgt taagaagctt attaagttct ttctgctagc aacatcttca
    48301 aatacattat atccgttttt tcaagaacta tcaaggacat caatgtcctt aaaatctaac
    48361 catttcgtgt catttttagc ttatatctaa aaaaacatcc ctaaagacga actttagaac
    48421 tgttttgata cgaggacaag gacatttttg tcactgattc actatgttta taaatatttt
    48481 ttgacatcct cttgccattc ctctgtcaat ttctttacta gaaattcatc tccaattagc
    48541 tgcgcaaatg ttttagaaga ctgataaaat gattcagcta aactaaaatc tctttcttct
    48601 cttaatgctt gcttccacaa aaacataaat acaagaggtt tcttttgata atcttgagtt
    48661 ttatccataa tttcttgtaa acacgataga taatcattaa aacaatcagt tactcctacc
    48721 ttttcaagac aacacattcc tgaaataaga gtatctctaa ttataaagta attctctatt
    48781 tgagttacct tcttctgttc caaaagaaag agcattagct tttcgatttg atttataaat
    48841 ttggcaagat cttttctaat gagcatttga taaaaaaaca aacgaatcaa caacatatca
    48901 tttattgaat aagcttcttt ttctataatc tgaggcatat gttcctcaag tattaactct
    48961 gcatattcag gccttctagt tctagaagta tccaaacacg cctgcaatac ttcacatgct
    49021 aattgttctt ctttaggaag attatcaaag tatgttttat aaatctcttc caaacacgct
    49081 tccttcttat cgtactcctc ttctttacca tagattggtt cacgtaaaat ctggtatttc
    49141 aattctaaat aagcaggagg aagagctgaa aaatccggca taaggctata aactggaact
    49201 cctagccggc gagcaatata ggctaacttg ggcaaactcg gttgcgaagc tccactttca
    49261 attcgcgaca gttgacgaac tgtcagttct tgctcatctc cacaaaaatc tggacgacta
    49321 actccttttt ctatccgaat ctctttaatt ttttgaccaa ttaacatcag acgcctcctc
    49381 ttctacctgc ttcgaaaaat actgtgaaac ttaaaaaatt gtaacggtca catctttcct
    49441 actcataaga tttcatagct tcttccactt ctgccaaagt aaccccaaac aactctaggc
    49501 gtttgaggag ttgcttgccg ttggaatagc cgattcggag agtctctccg agatattctc
    49561 tacgcttacg gctgtctgcc cctgctagaa aaccaaggcg aatcaaatcg ctacgactaa
    49621 tgtcaaactg actctcatgt tcaaattgtt ctgtcacctg agctagagcc gttttcaggt
    49681 cttcatagct ggcatgctca attcccagag aacgcccctt ggtcttggac ttgggaacag
    49741 cttcatctcg cttgagaaag gcatgctgaa ctgttggaat gaccatcatg atcatgcgcc
    49801 gaatccgttc cccattaaaa tctgggtctg taaagacaat gactccatga cgttggtgca
    49861 ggcgctgaat ccgctctata tcctgagcat tgatggcaga acctcgagtc tcataggtct
    49921 ccacatcgaa ataacgtttg agattgaccg tatcatcacg cccttcaacc acgataactt
    49981 gagaaatttt ctctttcatt acttgctgtc cagtccaaaa attcgttctg catttgcagt
    50041 cgttgctacc gccagctctt ctgtcgtcat accacgcaag tcagcgataa agtcgaccac
    50101 atagcgagta taggctgttt tattttcacg accacgcttg ggtacaggtg ctaagtaagg
    50161 cgcatctgtt tccaccaaca tcttgtccaa aggtaactct ttagctgctt cttggaggtc
    50221 agttgccttc ttaaaagtca ccactcctga gaaggaaatg gtcataccaa gatccacaaa
    50281 cttctctgcc cactcaagcg tccctgaaaa tgaatgcatg ataccaccac gaggaccaac
    50341 gccctcactc ttgataatct cataggtatc ttccagcgca tcacgggtat ggacaacaaa
    50401 aggcaaatcc aagtccttag atagctgaat ctgacggcga aaaacctgct cctgcacctc
    50461 tttgggcgct gtcatccaat ggtaatctaa gccaatttca cctaaagcca caaccttgga
    50521 atgttttaac ttatccaaca agtaagcctc aacttcctct gtataagtac cagcttctgt
    50581 aggatgccaa ccaatagtcg catagagctg ctcatactca tctaccaact ccaaggcatg
    50641 ctcaatcgtc ggtttatcaa aaccaacaat attcatctgt gtcacaccca tctcagcagc
    50701 caaggcaatt tcttctgcct cacgacctgc aaattcttct acattcaagt gtgtatgtgt
    50761 atcaaaaatc atctcttcta acctcgtttt ctatcttcta ttataccaaa aaagaggagg
    50821 ggcacctaat ttttcggttt cccctcctct cttcaataga gagctattct gctatctttt
    50881 ctatccgata ttgcccatct cctattccac agttagagac agaagagatt ggctacattg
    50941 atagactatt cctattcagc taaagtatgt gattatcttg ggttctcact tttctcaccc
    51001 atcactagga ttgatgactt ctcaaaatcc cccttataat ctaactttaa gtagagaata
    51061 gaattttcta gctgttccat tttctacgtc tagtctttct tcctagcaaa gcaaaaccac
    51121 tggttgccgc cactagacca agactagcaa gtgctgcact tgatgctgaa cctgtgttag
    51181 gtaattgttt gccagcaggt gactggtagg taacatcttg cattgttcct gcagttgctt
    51241 gcggtgcact tgttgtctta ggagcagcat taggagccac tggtctctta agaactgtaa
    51301 ccatggcaat ggcttgcact ccaatcgttt ctgcttcctt cacatcttcc atagttttcg
    51361 tattttcaat ctctttgaga gctgcttgtt tttctgcttc cactcttgct aaaagttctg
    51421 ctttttcttt atcagaaagc ggtgcgcctt tgatttcatc ctgcttgtcc ttggctgctt
    51481 tttcaatggc atttttagct gattcttttt cagtagctaa ttgcttagaa gcttgtgatt
    51541 gagctgagtt ttgtgaacct gtgtgagctg gtccacctgc ctggctacca ccgcctgcat
    51601 tcgcattagc atctgagctt ccagtattgc ctcccttatc tacacctagt gtagtttctg
    51661 gcttatactc tggtgtagct tcttgagtta cagattcacc tttcgcagat tgttgaactg
    51721 tatcttttcc tagaatcgtc actactgaac catctgggaa tgtgattgtt gctgtaccat
    51781 ctccagctac ttcaacttta tagcaaaatg aaacaataac aggacaaatc gatcaggaca
    51841 gtcaaatcga tttctaacaa tgttttagaa acagaggtgt actattctag tttcaatcta
    51901 ctataacatc gcttccgaat ccatttgcat ctactgaact tttttacaaa aataaaaatc
    51961 agtagactcg agttcctact gatttttgat agaattcgtt tggattatgc agccaaaact
    52021 ttgcgtcctt tacgacgacg agctgccaat acgcgacgac catttttagt tgacatacgg
    52081 ttacggaatc cgtgtttgcg cgcacgacga agtttacttg gttgataagt acgtttcacg
    52141 atgaatacct cctcatagat tttgtattcg tttagccggc tataaagtga tcagttacta
    52201 aacatacttt actattctat ctgattcttt cacttttgtc aatagctcta ggcaaatgtt
    52261 tccagctttt tcgaatgcaa gccctatcta cgatactgtt tcaagaaacg agtcatcttt
    52321 tcttggattt gggctaactc atcaacacga ggaaggtaaa cgatacggaa gtggtctggt
    52381 tcctgccagt taaagcctcg accatgaacc aagagaacct tttcctgctt caagaaatca
    52441 aggacaaact gctcatcatc atcgatacgg tacatattgc ggtcgatttt tgggaagata
    52501 tagagccccg ccttgggttt aacggcagac aaacctggaa tatcttgaat ggcattatag
    52561 atgaaatttc tttgctcgta gattcgtcca ccaggaagaa gcaattcatc gactgattgg
    52621 tgacccccca aggaagtttg tacgacttgt tgggccaaaa cgttagagca aaggcgcata
    52681 ttggacagca tattgagccc ttcgatatag cccttaacat gagtcttagg gccagacaag
    52741 accatccaac ccacacggaa acctgctatg cggtgggatt ttgacagacc attcatgctg
    52801 acacagaaga catctggtgc caagctcgcc acaggcgtat gcacatgtcc gtccattacc
    52861 atgcggtcat agatttcatc cgcaaagata atcaaatcgt tttgacgggc aatctcaata
    52921 atctccagca agagttcctt aggataaagg gctccagttg ggttatttgg attgataagg
    52981 acaattgcct tggtattgga agtgattttt gacttgatat cgtcaatatc tgggtaccat
    53041 tccacagctt catcacagat atagtgaacg gcatttcctc cagctaggct gacagccgcc
    53101 gtccatagag gatagtctgg cattggcact aagacctcat ccccattgtc caaaagcccc
    53161 tgcatggaca tgacaatcaa ctcactgaca ccatttccaa ggtaaatatc atcaatatct
    53221 acgtttggga atttcttcag ctggcaatac tgcatgatgg ccttacgggc tgagaaaatc
    53281 cctttggagt cagaatagcc ttcactatca cgcgcattca taatcaagtc atgaatgacc
    53341 tcgtctggcg ctgtaaagcc aaattctgct ggatttcctg tattcagacg taaaatcttt
    53401 tctccattcg ctcgcatccg catggcttct tccaatacag gaccacggat atcataagca
    53461 acatgctcta acttactaga cttgttatat tctttcatct tgtttcctca attcatcagg
    53521 atagtaacat tataccacta gaaagagaat gcgacaagtt tactgaaatg tgttactagt
    53581 ttcgtataga agaaaaacct tgctaaaggc gaggttaaga acgtagagat agcaggtatt
    53641 ttgcaaagac acatcacata ccaaaagata aacctagaaa aagcaagcct agaaaggagt
    53701 cataaagaag attaaacatg aggaaaagcc cccatatcat caagtaatcc caacgcccac
    53761 ttcgttttgc aactagaaat aagattagat ggtagagtac atgaaaaact aaaaatccaa
    53821 taaaacttgg ataaagaagc ggtaccagac tctctaattg acagatcatg atcacttcta
    53881 ccaagactga aactaggata attccataat aaaggaaatt tgatttttga aaagagtttt
    53941 tcatcattct cccttccttc acttctttcc tgctatcctt tcttttattt tatcatatat
    54001 ttatatagag tttaagccct aatattcttt tgaaaaatac tttttttgct ttacttctat
    54061 agtgaaaagg tttacaatta tagtaagaaa atttcaggag gtttcattat ggcacaacgt
    54121 taccaaaata tcatggtcgc aatcgatggt tctaaggaag cggacttggc ttttgtcaag
    54181 ggagttcatt ctgctctacg aaacgacgct aaactcacca tcgcacatgt cattgacaca
    54241 cgcgctctcc aaagcgtatc cacctttgat gctgaagttt acgaagaact ccaagtcgac
    54301 gctgaaagtc tgatgaaaga gtacgaaaaa cgtgctaaag atgctggggt agcagatgtt
    54361 catatcgtca ttgaaatggg aaatccaaag accctgctag cacgtactat tccagatgcc
    54421 gaggaagtgg acctcatcct cgttggcgca actggtctca acgcctttga acgcctcttg
    54481 gtcggctctt catctgaata catactccgc catgctaagg tcgatttgct ggttgtgaga
    54541 gaacaagaaa aaaccttata atcacaaaga aaaggagccc ctagctcctt tttgtttacg
    54601 atttatttct ctctttatgg cgttcgtaag ccttgagctg gcgctgcagt tcctttttaa
    54661 tagcaggttc tggagcatat ttttcttccc aattatctgg ttttaagatt ttatgggtca
    54721 ctggatcaaa atgagccttg ccatctggaa aaattttccc catattggcc tgatggacaa
    54781 tatcaaaaat acgttctggg tccaccccca tcaagacaaa actgccgtag gtgaagtaaa
    54841 gcgtgtcaat caaggcatcc acttgcccta tcaaatcttg ctgagcaggt gtcttcttgg
    54901 ctactttatc tgctgcctta tcaagggcct gatgaagttg cgatacagct tgaccaaaat
    54961 cttcttcaga aggactggct gctcgaacaa actccaccaa ttcttctatt ttaaaaccag
    55021 ccctatgggt tgcaccctct aaatcccaag ctcgaggttc ttcttgggtt cgttcatcca
    55081 tcatgtggtg gaaggtcttg accttattga aatgatagtc acggctgaca aagacttttt
    55141 ctgaagacaa aacaccaaaa tgttccaagg ccttgtggat cccatcttgt tgattgctag
    55201 tggtaatgtg cttggcagct tccttgacac tgctactacc atttcccata gcgaccgaca
    55261 taccgacgcc agccagcatt tcaaggtcat tatctgagtc accaaaagcc atgacttgat
    55321 tgaggtcaaa gccatattct ttcccaactc ggcgaatgcc ttctaattta gaatttccct
    55381 gattgatgac atccgatgca aaaggattgc tacgtgtcaa tttcaagtct tcaaaatcag
    55441 ctgccgcctt ctcagattct tctggtgtca tcagcatcaa aacttggtag ataggctgat
    55501 tcatcaggtg aagcaggtcc tcttcctttt ggggaacaac cttgctgacc atgcgattaa
    55561 aagactgact caccgtccga gttaaaacag agggaacgaa gcgactaatt cgttgggaaa
    55621 aagaacccag accaaaggac atgattttag aacccaacat ggcatccttg gtccctaggg
    55681 caatctccgt gccctctttt ttagcatagc taattagatg gcgcaaatgt aacttggaaa
    55741 tagggctcgt gaacaagact ctgtctttac taaagatata ctggccatta taggttaccg
    55801 caaaatccag atccaaatcg tccatcaatt ccttaacaaa aaaaggtcct cgccctgtcg
    55861 ctacgccaac tagtacccct tgttctttga caatcttaat cgcatcctta gtggatttca
    55921 aaacactctt gcgattgttg accaaggttc catcgatatc aaaaaaaaca gctttgactt
    55981 ccatcctatc ccaatctccc cttttgtgat acaatgatta taccacattt cagaaagagt
    56041 tagtaaatca tgcctaagaa aatccttgtt ttacatacgg gtggaactat ttccatgcag
    56101 gccgatgctt ctggcgctgt tgtgacgagt tcagataatc ccatgaacca tgtgtccaac
    56161 ccacttgaag gaatccaagt ccacgccttg gactttttta accttccaag tccccatatc
    56221 aaacccaaac atatgctggt cctctaccag aaaattaaag aggaagcaga taactacgat
    56281 ggagtggtga tcacacacgg aaccgatact ttagaggaaa cagcctattt ccttgatacc
    56341 atggaagttc cccatatgcc tatcgttcta acaggagcca tgcgtagctc caatgagctc
    56401 ggtagtgatg gtgtttataa ttacctaagt gctttacgag tggccagtga tgacagggct
    56461 gctgacaaag gagttttggt cgttatgaac gatgaaatcc acgctgccaa gtatgtcacc
    56521 aaaacacata cgactaatgt caacaccttc cagactccaa cacatggccc cctcggtctc
    56581 atcatgaaac aggaaatcct ctacttcaaa acagctgaac ctcgtgttcg ctttgacctt
    56641 gatcacatac aaggtttagt ccctatcatc tcggcttatg ctggtatgac agatgagctg
    56701 attgatatgc tggatttaga acacttggac ggtttgatta tccaagcctt cggagctggt
    56761 aatattccca aagaaacggc tcaaaaatta gaaagccttc tgcaaaaagg aatcccagtc
    56821 gctctggtat cacgatgctt taacggtatt gccgagcctg tttatgccta ccagggtggg
    56881 ggcgtacagt tgcaaaaagc aggcgttttc tttgttaaag aactcaacgc ccaaaaagcc
    56941 cgcttgaaac tcctcatcgc cctcaatgcc ggactaacag gacaggcttt gaaagactat
    57001 atggaaggct aatactcttc gaaaatctct gcaaaccacg tcacgtcgcc ttaccgtatg
    57061 tatggttact gacttcgtca gttctatcta caacctcaaa acagtgtgtt gcgcagcctt
    57121 taatcagccg cctagtccgc tctatggtat tcattaagtc aacatctctt gtttaagagc
    57181 accaaatcag gaaatcttct cgattccctg attttttcta tttacgtttt cgtgttgagc
    57241 tacgttctgt caaaccatga ggtaagagaa cttcacgttc ttccaactct tccttatgca
    57301 taatcttggt caacatacgc atactaatgg caccaaggtc ataaagaggt tgggcaatcg
    57361 ttgtcaagtt tggacgggta aagcgtgaga tttgtgaatc atcactagta ataatttcaa
    57421 aatcttctgg cacagaaaca cccttatcag ccaaaccgtt caagactcct gctgccaact
    57481 catcacctgt cacaactgct gcagttgcat ttgatgaaat caaacgctct gctaaggcgt
    57541 aaccatcatc atagctatat ttagattcaa ataccaaacc ctcactataa gtgattcctg
    57601 cttttttcaa ggtttccttg tagccaacta aacgaacctt accattgatg tcatccacta
    57661 gcggaccgct aacgaaagca atacgctcat tttctttagc aaggtaactc actgcatcaa
    57721 ttgttgcttg cttatagtca atattgacac ttggcaactg gtgctcaaca tcgacagttc
    57781 ctgcgagaac aatcggagta cgtgaacgcg aaaattctga gcgaatttta tctgtcaagt
    57841 gataccccat atagataatg ccatctacct gctttgaaaa gagggtattg acaacagaaa
    57901 cttctttctc gttatcttca tcgctattag ctaggacaat attgtacttg tacatttctg
    57961 caatatcatc aatcccctta gccaaactcg aaaaataacc attggtaata tttggaatca
    58021 cgacaccgac agtggttgtc tttttacttg caagaccacg cgcaactgca tttggacgat
    58081 aatccaaacg atcaattacc tctagcactt ttttacgggt attctctttt acatttttat
    58141 tgccattgac cacacggctg accgtcgcca tggaaacacc tgcttcacga gcgacatcat
    58201 aaatggttac tgtatcatct gcattcattc cttttcctgt cctttctatc tcacacattc
    58261 ttttacaagt agaggtactg attgaagctc tatatctact tacaaaagtg aagatgtgaa
    58321 aatttcgttt tcatatttct acttattcca ttctatcact aattgtaaac actttcaagt
    58381 gttttttgaa gattgattga aaaaatttca tagaaaacct aggtttagct ccttgctacc
    58441 accttagact aaacaaaaag gaggaaacta agccctccta aagttatagt aaaatgaaat
    58501 aagaacagga taaatcgatc aggacagtca aatcgatttc taacaatgtt ttagaagtag
    58561 aggtgtacta ttctagtttc aatctactat aggtattgtt ccattcacta ccgtcaattt
    58621 tagcacatag tcttcatgaa aatattatat catcataacc aaccagattc tttcgcgata
    58681 ttagctgcct ctgttcgatt acctgcatct agtttcgaaa gaatattggt gacatagttt
    58741 cggactgttc cgttggatag ataaagtttg tctgcaattt cttggttaga gaagccctga
    58801 gcaattccct ttaaaactgc gatttcttgc tccgttaatg gattgggatg catcatcacc
    58861 acttccatca attcaggcga atactccttg cgtccttcga ggacggtgtg caaggtttgc
    58921 atgaggtctg caatgtttct ttcttttaat acataagcat ctactccagc cttgaccgca
    58981 cgttcaaaat acccaggacg cttgaaggtc gtcaccacaa ccacctttgt ttcaagcttt
    59041 tctgctcgta tccactccaa gacttcaaga cctgtcttaa caggcatttc tacgtcaagg
    59101 atggcgatat ctacagactc cttttctaat agttggattg cttcttgccc attcttggct
    59161 tgaaagacag actctacatc cggttgaagc atgagcaact ggcacatggc atctcgcaac
    59221 atactttgat cttctgcgac taatactttc atctactttc tctccttata aagtagtcga
    59281 acctgcactt cagttggatg tttctgactg attacactta cttctcctga aaatggaaaa
    59341 acacgatttc ggactgtatg gagctcatcc ccgcttatag aggcaaagcc acagccatca
    59401 tctctcactg ttagaatgag ttctttctct gtccgttcta atttcaagta gactttagac
    59461 gctttagcat gtttgatgat attggtcact aattcaagca aaatcatgga agccgttgac
    59521 tccaattcct gagttaagct agacttgtcc aagtgattct caacttgaac ctcaattcca
    59581 gcaatttcta acatcttttt cacagtctct agttcggatg tcaaagttct agacttaaga
    59641 ttttccacaa tggttcgcac ttcattcatg gaatccttgc tgatctggtg aatttctttt
    59701 aattcctttt ccacctgtgg ataagcctcc atctgaaata actgcaaggc taaatctgtc
    59761 ttgacactca gcatagcaaa ggtatgtccc agactatcat gcaaatcctg accgatacga
    59821 ctacgttcat tttcagcaag caatagattt atctgagcat tttgcttgac ctgagcttct
    59881 ttcaaatcct cgacaatacg aatccgaacc aatccaaaag tcattaaatc gacaaaagta
    59941 agaattacaa gtagatagaa tagaaactca acttcgattc tctgaaaaat caacagttgc
    60001 cccacaacaa ggacttgagc aagaagaaaa gtccagacat gtaaagactt taaactacgt
    60061 acgctgaaat gataacttaa gagattggat aggaaaaaga aaaaccagat ataattaaca
    60121 gcaacaaagg cagtattccc aactacataa gtcagcatga ggccccaata tagccaagat
    60181 aggcgctggc tcttagttgt taaaacaccc aaatatgcca ctacaaatag aatatcaatc
    60241 aataaatgcc aggcagaaag ccacccagtc actacagaca ggatggggaa aatcataaaa
    60301 attaaactga tccaaaacat ataatgtatt cttttcagtc tttcaagcat taagcattct
    60361 ccttatgacc ttgaaggtaa atggtcaaac caaacaaaac tactgaaaaa acaagtaaat
    60421 aaactgtggc tgatagattg atgccaccct catttaagaa ggtcttgagc aactccatca
    60481 actgataggt cgggagacac ttacctacta cttgcatcca gtctggaaat aaagagatag
    60541 gcatccagag tccacctaaa acagccaacc ctagataaag aagattgccc acgacagaca
    60601 tcaactgact agttggtaag agagtcaagg tcaaaccaag cgctacgaag gcaatacttc
    60661 ctactatcag caaaagtgca gccccaatcc aatttccaag agacatgtcc acacctctta
    60721 caaaatgccc aactgagaaa accaccaaga ttgaaaccaa ataatcaacc agcatacttg
    60781 ttatctttga tagataatat tctaccatat ttacagggct atgacgcaat gttttctgcc
    60841 agttgttgat cttgtcggta tgtaaaacaa ctgggaatga gaagatagct gttgacatca
    60901 tggaaaatgc agtcatggag ataagataat cacgcataaa attcgcgagt tcacctggtg
    60961 tgtcctgata gataccagaa aaaaataaat agaaagccgt cggcatccct accgacaata
    61021 gataatagat taattgtcgt ttggtcaata aaaattctat cttactaagt gctatccatc
    61081 gtttcatctt agttatctcc cttctgcgtc tcttcaaaga ttgtattcaa caaactacga
    61141 ttattaactt cgatttcttg catcctacat cctgcttggg ctaatagttc ccagaaagca
    61201 tctgcttctc gagtgactac ttgtaaagaa tcttgcttta gggtccagtt ttcaaccaaa
    61261 tttgactgct ctacgacttc cttgtaagct ataggaagga taaagtgctt ttctatttcc
    61321 tcgctacgca tagctagagg cgtcgtatct cgaatcaact ctcccttatt taagagcaaa
    61381 atgcggtctg cagtgtgttc cacttcctca atataatggg acgaatagag aatggtgact
    61441 ccttgcgctt ttaactcctg gacaatttcc caaaaacgtt gacgagttga ggtatccatg
    61501 gacgcagtag gctcatctaa aaaaacaatc tttggtcgcc caattaaggt caagacgaaa
    61561 gaaaagagac gcttttgacc gcctgataat ttttctgcca actgttcttt ttgttgcttg
    61621 acaaactgca atagttgatc aatttcctga ttgctcaaag gatttggata gatacgttga
    61681 aagaaagcaa tcaactcttt aacttttaat ttctgaacga ttacattttc ttgagggagg
    61741 taagccctag tatagtctaa cttagaactc gtcactggta aaccttgaat agatacttga
    61801 ccgcttgtga ccagtttatc tccaagcaaa caatctaaga gtgttgtctt tccggcacca
    61861 tttggaccaa ttaaggcaac acattcacca tcgttgattt caaaggagat attccgcaaa
    61921 atttccttgt cttttatttt cttactcaat ttctcaactt taaccaccgt catgagactc
    61981 tcctttcaac cactccattc ccataaggaa aacgacgaaa atcataaatc caaaccccaa
    62041 agcaccacga atgaattggc gaagcaaggc ttgatcaaac caatcagtaa acatttccac
    62101 taaccatacc aagagtgaca ggccgataaa gaaatagatg atccctctct tcattcctca
    62161 aactcctttt tcacatctct gactaatttc aaaccttctc taacaagcca agacatgatt
    62221 ccaaagccag caaagacctt ccaaggaaaa tggtagaaat cctcatccaa tcccgaaaac
    62281 atgagatagg tcataactcc tgctactact aaacttactg cgataatcat tttatttctc
    62341 atctcttctt cccccatttc atactacaat tatagtcttt taaaatcaga ggagacagaa
    62401 gcttctgtca ctaaaaaata tgacaaatgt cataaaaaat tctgttcaaa acaagcaaga
    62461 tacactatac aataaaacac aatcagaaaa atctaaggca acttcctcaa aagagatatc
    62521 aaacccaatt cacaccataa tgtaaactaa tacttattta aaatcaaaaa gagtaaaaat
    62581 ttttatcaga caaacacat
//
LOCUS       DAVAGB010000004        62511 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVAGB010000004 DAVAGB010000000
VERSION     DAVAGB010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 62511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62511
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.004"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(141..1010)
                     /locus_tag="VQO19_000312"
     CDS             complement(141..1010)
                     /locus_tag="VQO19_000312"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HET1348628.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(1012..2298)
                     /locus_tag="VQO19_000313"
     CDS             complement(1012..2298)
                     /locus_tag="VQO19_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HET1348629.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(2449..3186)
                     /gene="mecA"
                     /locus_tag="VQO19_000314"
     CDS             complement(2449..3186)
                     /gene="mecA"
                     /locus_tag="VQO19_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HET1348630.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVVFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(3386..4420)
                     /locus_tag="VQO19_000315"
     CDS             complement(3386..4420)
                     /locus_tag="VQO19_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET1348631.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(4449..5882)
                     /locus_tag="VQO19_000316"
     CDS             complement(4449..5882)
                     /locus_tag="VQO19_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HET1348632.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(5898..6884)
                     /locus_tag="VQO19_000317"
     CDS             complement(5898..6884)
                     /locus_tag="VQO19_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET1348633.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATDLSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(6886..7989)
                     /locus_tag="VQO19_000318"
     CDS             complement(6886..7989)
                     /locus_tag="VQO19_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET1348634.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYTSKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(7979..8824)
                     /locus_tag="VQO19_000319"
     CDS             complement(7979..8824)
                     /locus_tag="VQO19_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET1348635.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLCYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(9103..10377)
                     /gene="psr"
                     /locus_tag="VQO19_000320"
     CDS             complement(9103..10377)
                     /gene="psr"
                     /locus_tag="VQO19_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HET1348636.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSSPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(10374..11222)
                     /gene="pheA"
                     /locus_tag="VQO19_000321"
     CDS             complement(10374..11222)
                     /gene="pheA"
                     /locus_tag="VQO19_000321"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET1348637.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     NYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAENPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(11219..11695)
                     /locus_tag="VQO19_000322"
     CDS             complement(11219..11695)
                     /locus_tag="VQO19_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HET1348638.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIVADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(11688..12971)
                     /gene="aroA"
                     /locus_tag="VQO19_000323"
     CDS             complement(11688..12971)
                     /gene="aroA"
                     /locus_tag="VQO19_000323"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HET1348639.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGASVIIEKECTRNHTEDMLKQFGGHLSVDSKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(13063..13401)
                     /locus_tag="VQO19_000324"
     CDS             complement(13063..13401)
                     /locus_tag="VQO19_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HET1348640.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(13412..14515)
                     /locus_tag="VQO19_000325"
     CDS             complement(13412..14515)
                     /locus_tag="VQO19_000325"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HET1348641.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(14525..15691)
                     /gene="aroC"
                     /locus_tag="VQO19_000326"
     CDS             complement(14525..15691)
                     /gene="aroC"
                     /locus_tag="VQO19_000326"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HET1348642.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(15701..16768)
                     /locus_tag="VQO19_000327"
     CDS             complement(15701..16768)
                     /locus_tag="VQO19_000327"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HET1348643.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(16787..17641)
                     /locus_tag="VQO19_000328"
     CDS             complement(16787..17641)
                     /locus_tag="VQO19_000328"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HET1348644.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(17631..18308)
                     /locus_tag="VQO19_000329"
     CDS             complement(17631..18308)
                     /locus_tag="VQO19_000329"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HET1348645.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAYTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(18305..19468)
                     /locus_tag="VQO19_000330"
     CDS             complement(18305..19468)
                     /locus_tag="VQO19_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HET1348646.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(20153..21787)
                     /locus_tag="VQO19_000331"
     CDS             complement(20153..21787)
                     /locus_tag="VQO19_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348647.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEIPIYFSSMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALAGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVTLVMVVAVHFLAQTTVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFFPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPVLTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLST
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(21768..22517)
                     /locus_tag="VQO19_000332"
     CDS             complement(21768..22517)
                     /locus_tag="VQO19_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1348648.1"
                     /translation="MIEFQNVSKLYGDKKALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            22696..24150
                     /locus_tag="VQO19_000333"
     CDS             22696..24150
                     /locus_tag="VQO19_000333"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HET1348649.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(24240..26858)
                     /gene="alaS"
                     /locus_tag="VQO19_000334"
     CDS             complement(24240..26858)
                     /gene="alaS"
                     /locus_tag="VQO19_000334"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HET1348650.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNHNASQLSSKLVAIVADNAEVEAVSEGTTSLIFAETPFYAEMGGQVA
                     DHGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQPKIQELLDAVAGKL"
     gene            complement(26880..27365)
                     /locus_tag="VQO19_000335"
     CDS             complement(26880..27365)
                     /locus_tag="VQO19_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HET1348651.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(27640..27879)
                     /locus_tag="VQO19_000336"
     CDS             complement(27640..27879)
                     /locus_tag="VQO19_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348652.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILSHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(28124..29194)
                     /locus_tag="VQO19_000337"
     CDS             complement(28124..29194)
                     /locus_tag="VQO19_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET1348653.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(29191..29964)
                     /locus_tag="VQO19_000338"
     CDS             complement(29191..29964)
                     /locus_tag="VQO19_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET1348654.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(29961..30767)
                     /locus_tag="VQO19_000339"
     CDS             complement(29961..30767)
                     /locus_tag="VQO19_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET1348655.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWIMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(30748..31905)
                     /locus_tag="VQO19_000340"
     CDS             complement(30748..31905)
                     /locus_tag="VQO19_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1348656.1"
                     /translation="MKKSIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRNIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(32066..32971)
                     /gene="murB"
                     /locus_tag="VQO19_000341"
     CDS             complement(32066..32971)
                     /gene="murB"
                     /locus_tag="VQO19_000341"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HET1348657.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(33083..33835)
                     /locus_tag="VQO19_000342"
     CDS             complement(33083..33835)
                     /locus_tag="VQO19_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HET1348658.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(33845..34576)
                     /gene="budA"
                     /locus_tag="VQO19_000343"
     CDS             complement(33845..34576)
                     /gene="budA"
                     /locus_tag="VQO19_000343"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HET1348659.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIGEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            34718..35989
                     /locus_tag="VQO19_000344"
     CDS             34718..35989
                     /locus_tag="VQO19_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HET1348660.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQPGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(36009..36824)
                     /locus_tag="VQO19_000345"
     CDS             complement(36009..36824)
                     /locus_tag="VQO19_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET1348661.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGIYQSYLEKAASLTEVEE"
     gene            complement(36981..37634)
                     /gene="phoU"
                     /locus_tag="VQO19_000346"
     CDS             complement(36981..37634)
                     /gene="phoU"
                     /locus_tag="VQO19_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET1348662.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(37646..38404)
                     /gene="pstB"
                     /locus_tag="VQO19_000347"
     CDS             complement(37646..38404)
                     /gene="pstB"
                     /locus_tag="VQO19_000347"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET1348663.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(38417..39220)
                     /gene="pstB"
                     /locus_tag="VQO19_000348"
     CDS             complement(38417..39220)
                     /gene="pstB"
                     /locus_tag="VQO19_000348"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET1348664.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(39231..40115)
                     /gene="pstA"
                     /locus_tag="VQO19_000349"
     CDS             complement(39231..40115)
                     /gene="pstA"
                     /locus_tag="VQO19_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET1348665.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(40105..41022)
                     /gene="pstC"
                     /locus_tag="VQO19_000350"
     CDS             complement(40105..41022)
                     /gene="pstC"
                     /locus_tag="VQO19_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET1348666.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGIWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(41022..41900)
                     /gene="pstS"
                     /locus_tag="VQO19_000351"
     CDS             complement(41022..41900)
                     /gene="pstS"
                     /locus_tag="VQO19_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HET1348667.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(42474..43778)
                     /locus_tag="VQO19_000352"
     CDS             complement(42474..43778)
                     /locus_tag="VQO19_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HET1348668.1"
                     /translation="MQFPEGFVEKYKEILGDEARNFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKSSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(43779..44552)
                     /locus_tag="VQO19_000353"
     CDS             complement(43779..44552)
                     /locus_tag="VQO19_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HET1348669.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(44542..44820)
                     /locus_tag="VQO19_000354"
     CDS             complement(44542..44820)
                     /locus_tag="VQO19_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HET1348670.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(44820..45221)
                     /locus_tag="VQO19_000355"
     CDS             complement(44820..45221)
                     /locus_tag="VQO19_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HET1348671.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(45431..46048)
                     /locus_tag="VQO19_000356"
     CDS             complement(45431..46048)
                     /locus_tag="VQO19_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HET1348672.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLYLKSRRK"
     gene            complement(46038..46811)
                     /locus_tag="VQO19_000357"
     CDS             complement(46038..46811)
                     /locus_tag="VQO19_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HET1348673.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRGIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPMERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(46822..47559)
                     /locus_tag="VQO19_000358"
     CDS             complement(46822..47559)
                     /locus_tag="VQO19_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HET1348674.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSVVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(47564..48694)
                     /locus_tag="VQO19_000359"
     CDS             complement(47564..48694)
                     /locus_tag="VQO19_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HET1348675.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(48778..49167)
                     /locus_tag="VQO19_000360"
     CDS             complement(48778..49167)
                     /locus_tag="VQO19_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET1348676.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(49183..49566)
                     /locus_tag="VQO19_000361"
     CDS             complement(49183..49566)
                     /locus_tag="VQO19_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HET1348677.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(49567..50355)
                     /locus_tag="VQO19_000362"
     CDS             complement(49567..50355)
                     /locus_tag="VQO19_000362"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HET1348678.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGVLVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(50348..51283)
                     /locus_tag="VQO19_000363"
     CDS             complement(50348..51283)
                     /locus_tag="VQO19_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HET1348679.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(51413..51589)
                     /locus_tag="VQO19_000364"
     CDS             complement(51413..51589)
                     /locus_tag="VQO19_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HET1348680.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(51729..52436)
                     /locus_tag="VQO19_000365"
     CDS             complement(51729..52436)
                     /locus_tag="VQO19_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HET1348681.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESNLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            52587..53615
                     /gene="queA"
                     /locus_tag="VQO19_000366"
     CDS             52587..53615
                     /gene="queA"
                     /locus_tag="VQO19_000366"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HET1348682.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDSMFIY"
     gene            complement(54276..55403)
                     /locus_tag="VQO19_000367"
     CDS             complement(54276..55403)
                     /locus_tag="VQO19_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET1348683.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGYVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVLVPFTTEYEADNDLSAGQEQEITLGKNGKTVTTITYDV
                     DGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEIPIETEYLDDPTLDKGQEVGEIG
                     KITLTTIYAVDERDGTIEETTSRQITKEMVKRRIRRGTREPEKVVVPEQSSIPSYPVS
                     VTSNQGTDVAVEPAKAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGS
                     MKVNQWFQVGGKWYYVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(56118..56669)
                     /locus_tag="VQO19_000368"
     CDS             complement(56118..56669)
                     /locus_tag="VQO19_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET1348684.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(57067..57891)
                     /gene="nadE"
                     /locus_tag="VQO19_000369"
     CDS             complement(57067..57891)
                     /gene="nadE"
                     /locus_tag="VQO19_000369"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HET1348685.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRSETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(57888..59348)
                     /locus_tag="VQO19_000370"
     CDS             complement(57888..59348)
                     /locus_tag="VQO19_000370"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HET1348686.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEGLRFSDSDIAYLELLGYHGAFLNYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(59464..59952)
                     /locus_tag="VQO19_000371"
     CDS             complement(59464..59952)
                     /locus_tag="VQO19_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348687.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLTITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWIFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(59942..60151)
                     /locus_tag="VQO19_000372"
     CDS             complement(59942..60151)
                     /locus_tag="VQO19_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET1348688.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(60536..61264)
                     /locus_tag="VQO19_000373"
     CDS             complement(60536..61264)
                     /locus_tag="VQO19_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET1348689.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     ETSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVVITTIILLYFFTLKKSKKYSF"
     gene            complement(61280..62071)
                     /locus_tag="VQO19_000374"
     CDS             complement(61280..62071)
                     /locus_tag="VQO19_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1348690.1"
                     /translation="MNFALNKGEIVGLVGRNGVGKSTLMKILVQNNQPTSGNIISSDN
                     IGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKVKTYSL
                     GTKQKLALLLTLVTKPDILILDEPTNGLDIESSQIVLAVLKKLALNENVGILISSHKL
                     EDIEEICERVLFLESGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
BASE COUNT        18666 a        14103 c        11470 g        18272 t
ORIGIN      
        1 acaacctcaa aacactgttt tgagcagcct gcggctagct tcctagtttg ctctttgatt
       61 ttcattgagt ataaacttct tttcacaaaa aggatatgaa accctctggt caagagtttc
      121 cccatcctat cttctattct ttattttgct tctacacgga caccttgggt atcaactctc
      181 aagtcatgca gttttccttt gaaaggttgc ttttccaatt ctgccttaat tgttggcatc
      241 ttgtcatgag aagccagaac cataactgtc ggcccagcac cagaaaggta ggttgcatag
      301 gccccatttt ctttggtcac ttgcttaatc atcgcaaatt ctcttaccaa gtcctgacga
      361 tagcgctcat ggaagaggtc tccctcgatt gcttgcccag cggtcaccat gtctcctgcc
      421 aacaaggcag caaccgctac attggcgata gaacttgcag caacagcttc cttataagac
      481 aattttttag gcaagacact acggctgtcg cgagtacgta attcatagtt tggaatgtaa
      541 gctagaaaat cacactctgg aaagtctgct acgatagcag agacttgccc ttcaacagaa
      601 cttgcaataa cgagattacc ataaatggct ggagccacat tgtcaggatg cccttcaatc
      661 ttggtcgcta actgcaattt ttcatggtct gataagttga gttgacccag ttggttggct
      721 agttcaatcc cagcaacgat aaccgagctg gaagaaccca aaccgcgcgc caaagggaca
      781 tcactggtca ttttcaagcg tcttggttgc aagtctggta caatttgcaa agcgattttg
      841 agcaagagat tacgctcatc atgtggaatc catttgccaa tctggtgttc aatcagccac
      901 tcatctcgtt cttcgcagac ctcaatttga agatacttgg ttacagctac accgaccgag
      961 tcaaaacctg gcccgatatt ggcactggtt gcaggtacaa taatcttcat cttattctcc
     1021 tagcaccttg aaggtattca agaggtcgaa ttctgaaacc ttcttcaatt cagctgagac
     1081 attttcaagc tgggctttat taatcttgtg tgtgatgata acgacacgcg ccttgtcacc
     1141 ctctttgcca tcttgaagga tttgcttaaa ggaaatatct tgagcattga agatttcagc
     1201 caacttcaag acctgacctt ttgagtctag agccaagatt gagaaatagt agtttgcttt
     1261 gacatcttca ggatttgcca agaccaagtc acggctatat tcgttgaagt ctttgccaat
     1321 agtaccatca ttcaaacgac gaacgatacg gacaatatca gctacaacac ttgttgcagt
     1381 tggtttttga cccgcacctg gtccgtagta catagactca ccaataccaa tagattctac
     1441 aaagacagcg ttcattacgc cattcacact agcaagtggg tgcgctttag gtaggaaggt
     1501 tggagtcact tctgcagcaa tacctgaaga agtttcctca atagaaccaa ccaatttcac
     1561 tacgtaacca agctcttgag ctacagctac gtcttctggt gtgatattgc ggattccctt
     1621 gtgggctaca tcatcaaagg caatcttcat gccaaaggca aattgactca aaataaccat
     1681 cttgtaggct gcatcaatcc catctacgtc attcgtcgga tcgctttctg caaatcctag
     1741 acgttgtgct tccgcaagag catcatcgta agaccagcct tcttccacca tcttggtcac
     1801 catgaagttg gaagttccgt tgactactcc aagcacgcgc gtaattttat cagaagccaa
     1861 ggaatttgct aaagtacgaa gaattggaat cccaccagca actgctgctt cgtagtaaag
     1921 tgctaccttg ttagcttgag cgatttctag caattctgcg ccatggacag ctaaaaggtc
     1981 cttgttagca gtaacaacgt gttttccagc ttccaaggca cgagtgataa aggttttagc
     2041 aggctcaata cgccccatca attccactac gatagtaata tcctggtctg ataaaatatc
     2101 atccacattg gttacaaagt taaagtcatt ccctgctgca agcaagcgat ttttttcatc
     2161 ttcatccttg accaatacct tagcaacttt gatatctgaa tgtgctgatt gattgatttt
     2221 tcctccattt tcctttagga ggaaaggcac accacttgca acggtaccaa atcctagtaa
     2281 agcaatttta actgtcatct ttatctcctc gaaattttct aatatagcca ttataacaga
     2341 attttgtgaa aattcctatt atagtaaatc actatttcag tataaaaaga aaaaacgaat
     2401 cagacgattc gctcttctta aaatctgaaa atagctttcc agaaaggatt agccgatttt
     2461 ttgcagattg agcactgcat cgtgactcat caagacttga ccatactctt gtaagactga
     2521 gcgactgata tcactatcgt ctgcaaactc gcgcatacgg gccaacagcc aagctggata
     2581 tgggcttgga tgattttcaa tatccactaa aatggtcaaa taatagcgct cgttcatttt
     2641 gtagagttca gaagtttcca tttcaaaagt cactgtcttg gcaaaaacta ccaagtcagc
     2701 caacttagca aaagaaagga tgtagtagat gtaaggttct ttcttactct cagcttcttg
     2761 ttcagcctgc tcttgctctt cttccttggc ttcaacttgc tcaagagatt gaatggcttc
     2821 gatatcatcc ttggttttgt ctgcgatgct tttttccagg gttttgataa attcatctgg
     2881 agacatttga gccaattctt ccatatctgg caaatccgat aagtcttcaa aatctagatt
     2941 ttggtcaatc tttgacttgg tcacaaagac atctacctta tcaggttttg gagtcacacg
     3001 gaagctcaac atgcctgtat ccagaaagct atcaggcatc tctagttcat ccaagatagc
     3061 ataaaagaac tcttctgttt tttcttgagg aacgagaaag tcagcaatct ccattccacg
     3121 atccatcaaa tcctctaaag acatcgtgat ttttaaagtt gtatcactaa tttgtttcat
     3181 tttcattgct agtaacctca tactttcagt tctatctatt atactagatt tttacgattt
     3241 tatcaaaaga aggctcctct atacggatag attttcccta gggtctttct ataggagact
     3301 ccaaaagaaa atttctgcag acagatagaa aaagccttca aaatcagctc ttagccgatt
     3361 ttgaagacct tatacatcag aatacttata atttaaaggt tgctacacca aggatagaac
     3421 gatttaagtt tctgagaatt tgaagacttt gctcaaattt cttataacga gtcactccgt
     3481 actcttcaac aagaaggact gtatctcttt ccaaaagaga tgatacatcc tgtaaatcta
     3541 caaaatgcat tccttttaaa gcttcttgac tctgtttcaa tttatctagg atagctttat
     3601 ttgagctaac gatggtcaat tcctgtccag tatttttgta tgacaaaaca tctgctaggt
     3661 tagcaattgt tgtaatctct gttacaaaat caatttgata ctgagaaaaa tcacctactc
     3721 tattgattgt tggattaaag agataaacta acacatttcc catcacaacc aaaatcacac
     3781 aaaccactcc aataacaact aaacgaagaa tcagattttt cacatttaag ccaagcgctg
     3841 tttcaccatt tgcgttcaat tctttagagt tgatggtttc cagtttttca attttcacat
     3901 ttgcataggc atgtttaaat ttctcaatca acccatcaat ttttttctct aacaagtcat
     3961 tggcatcttt acttgatgtc aaaattttca caccaacccc tgcatcgtca atcatatagt
     4021 agacggtcaa ttttttccac caatagtcat tcgttgaatt tttcaaggtt gtttctgtcg
     4081 tgtctaattc actggcaatt tttttcaact cactgggttc tacatcattg aaaagataag
     4141 ctccattcaa attaccatca atcaatttcc cataaaaatc actataacca ccaatttgat
     4201 gattcaaaat cgttttggcc gactcttttg gaggagtgat tttatagata agataagttg
     4261 aataacttgt tgtatctttg acagtgtttt tattcctaac tgctttaatt gtaaatggta
     4321 cagcaatgag agcaaataaa gcgatgagag ctaaaatatt tgcttttcgc tttttataaa
     4381 gatttgcaaa caaatcagct actgaataat gttcaaacat gatttttttc tcctttgttt
     4441 agtagatact agttttcctt tgtaagcatt tttgctacaa atataatcac aagaacaatt
     4501 ccccagaatt gcattgtaaa taaattgaag aaactttctg aaaagctgct tcttggcata
     4561 aagaatagat tattcaagat gagtagggat aaagcaaata ggattgtcct tgagcgatag
     4621 gctacttgca gcatggctat aaataatacg ccgagtaaga aactaagcag aaagactcca
     4681 atcataccat agtcggtata caactccatg atataactac ttccgatacc atgccctttc
     4741 aagtattcct tgttcaagac aagataggat agattgtggg cataactatt actatcaata
     4801 gctagttcca cactattggt tgtatgttca aaggcttttc ctccgaaaat ggctcccaaa
     4861 ctcccccttg caaaataatc aagaacagga ccaaaagtaa aattacggaa atctcggtaa
     4921 gggaggctac tgttaaatag aaaacctcga gccagaacac caaaactagt tccttgttta
     4981 tagataaagt caagtaagat atcccagaaa cctgtatggg aaacttggac attatcccgt
     5041 acataattaa gtactcccat cgctaacatg agaataggag aacctacaaa aatcgctaac
     5101 ttttctttaa acccaatcca ttttcctttt tcagtttgct cccgcataaa gtaataaaca
     5161 aaagcaaata aaatacttaa aataaaggga tttcgtgtcc caattgccaa atgaatagta
     5221 ttagctgcaa taaaggagac aagcactgct gtggcctgca atttctttgg cttggttgcc
     5281 agatacatac acattgcata gaccgtaaag gtagacaaaa tgtaggtaaa ataaggcagt
     5341 ttactttcaa aatttgcata gtaggcatag taggaagtct gcaaacgata caagagccgt
     5401 tcaaataacc gaatgaaata gaaaggatag gttagaagaa aaactcctag tgatacaaag
     5461 cgtaaccgct tgatataaac ctcttttaga gaatttccta tatttgctac ttttattttc
     5521 ttcctagcta tgaagtaacg agccagaatg cctcctgtgg tcaagcccag aatcgaaacc
     5581 atgacaacta taaaggcaaa acgataggct attggatgat aggtatccaa agcaccatcc
     5641 ctaaaataat caatggtcgg tcttgatacc agaaatacaa aaatggttaa atagaaaata
     5701 aaatggatta agtaatactt gatatcattc caacaagcaa tcaagctact aaccaacaag
     5761 aacaataaag tagaaagtaa gctaacatta ttattattaa acagatacac aattccactt
     5821 actagcgtca aggcataact gactatggtc aaactaaata ataatcgttt cccatcaatc
     5881 acttggtcac ccccgttcta atgtaatttt ttagattttt caatattttt cagtaataag
     5941 aatcgatata aggaaatatt tatgaatagg gccaaagcac taattcttct ccccttacgg
     6001 aaaattggat tcctagaaat agcaaaggca tggcctttta aaaaacgatg aatctgagaa
     6061 taggcttcaa actgtttata ctgatcatct agcaacatct tatccagaat aaagaagtgg
     6121 gcataggcca atctgaaaaa agcgacctct ttcaagtcag gatagttttt cacaacttca
     6181 ttataaaact tttggtagat atcaatatag gctaaatcct tctctgcata gggtttggtc
     6241 gtaatactat cccctctatg gaaatagtaa taatagggtt tagtattaac cacatacttc
     6301 ttggccaact tgattaaatc aaaatggtaa taggcatctt cgtaaatcaa ccccttagga
     6361 aaggataggt cagttgcaat ctgtctcttg attagcttat tgcaaatcgt cccaggtatt
     6421 ttttcaccta tgaggtattc ctttagaaat gtttgagaat cacagacaaa atagtcatcc
     6481 tgattggctg actgtgggct ttcatcatta gcatagacat tcatgacacc acagctcgaa
     6541 acatccgcat cttcttgaac taattgctca tataagctct gaatcatttc tggatggata
     6601 taatcatctg agtcaataaa aatcagataa tccccgtgag cctgcttcat cccatcattt
     6661 cgtgcttgcg acaatccttc gttcttttta tgaagcactg acaccctgtc atcttgttca
     6721 gcgattgaat cacacaagcg accactttca tctgttgcac catcatcaac aagaataatt
     6781 tccagatttt gataggtctg cttctgaatg gaagctatcg atttttctag gtactgcgcc
     6841 acattataga ctggcacaat cacactaatt aatgcagttt ccatgctact cctctaatag
     6901 tttttctact tgttcgattt gttttgtaat tgtaaattgt tgaatgaatt ggctagcctc
     6961 atcgacatca aagtttgagg cagaagtcat gtaattagta atcgcctgag ctgcctcttg
     7021 attgctctca atgatttgtc caaatcgtcc ttcttgggat aattcctcag cccctccaac
     7081 gtccgtagag ataaaaggga gtcccagact caaggcctcc acatacactc caggaaaacc
     7141 ttcttgttta gacatagaca aaagaacttt cgtctgagat agatactgat aaggattttt
     7201 ttgataacca aggaaatgta catagtcctc aatcccatac tctttgactc gttttttcag
     7261 ttcctcttcc atatcaccag ccccgataaa atagagatga tagttttttc cctcttggtg
     7321 taataatcgt atcacttcca ctacacggtc agaaccctta ttttcctcaa tccgtccgat
     7381 agtacagata ctttgaggag caatctcgat atcgatcttc tcttgagatt tttctagaat
     7441 agtctgaaaa tcatatccat tgtagattgt ctgtaattta gaagtataat ctggataaac
     7501 ttccttgata gaattgctgg tcttttttga aatccctaca attgtattcg cagcatccaa
     7561 ctggcttcta tgtgattctc ttttagagct atccttaaga agttcttcaa tacttccatg
     7621 aatccaagat atcttcttga cttctcttct tttagagaac aacagtggtg gattcataat
     7681 ggtaaaagaa acttcaacat cataatcatc ttttacaagc aaacgacgag ccagtcttgg
     7741 aaaataaatt ctcattctcc acaaaaaagc tcgtaaccat ctggtttggc gataatcttg
     7801 aagggatttt aaaatgcgta catgctttgg aacagattca tatcccttgt caaagtgctc
     7861 catttcaaga atatcaatat catacttttc tggatccaga tttgaaacaa tggttgatag
     7921 aatcttctct gcaccacctc caagagaaaa agaccacata aaaaataaga tttttttctt
     7981 agccaccata ttctcccttg tattctgtat aagacttatc catatcagcg atgacagcat
     8041 catgatgcgg tacctgcttg tctgctggtg gaggcgtcat ataatcccca aaagcagttc
     8101 tgagatagac atcatagccg attggaatag gcatctctgt tccttcaaat ggcaagaaaa
     8161 gattgtcttc aaaagatgtg attgggtact tgtttctcat gtagccagga cctgagcata
     8221 attctgtaat gccatcacaa tcagccaaat catacttagt catttctttc tcagcttttt
     8281 tccagatgcg ataacagaga gattttggag tcaaacccag taaaatgcga cttccccatt
     8341 tcatgagagc accatgcttt tctggaatag tttgcgcaca aaagagtgaa taaatcaagg
     8401 cccaacgaac ctgttttttc cgctcagctg gatttttcgg ataataatcc aaaggcaaaa
     8461 catccaaggc cagaccatgt ggcaaatcca aatcctgctg ataaggcttg atacaggtag
     8521 tttccttgtc acgaatggta ataaaaagat tacgatcaac aaaatccttg tgactctttg
     8581 acaagaaata acgttcatct gcataacgag gccataattc tgctaatttc tcataatctt
     8641 tacgaggcat aaaaaagtct aggtcgtcgt cccaaggaat aaatcccttg tttcgaaggg
     8701 caccaatagc gcctccgcca cagagataac agagcaaatc atgttcttta caaaaggcca
     8761 caaaatattc agccatctcc agactacgag cctgaattgc ttttaaatca gtcatattgt
     8821 tcattattct ttctatcgta tcgtttcatt ataccacaaa caaggggtga aaatctattg
     8881 cagactgtaa aaaatcaaag cctgactact atccaaatag ctatcaaact ttgatttttc
     8941 tgtcttatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc cgtaggtata
     9001 ggtaactgac ttcgtcagtc ttatctacaa cctcaaaact gtgtttttag cagcctgcgg
     9061 ctagcttcct agtttgcact ttgattttca ttgagtatta tcttatctca agcccatttg
     9121 agcgagcttg gtttgatatt tgttttgatc aaccagcaag cccaagcctc cataaacatc
     9181 ataggcatct acccagtcac ccagttctgg aatcgtcaat ttttcaatac cattttttgc
     9241 tccatccaaa acagataaac cgtttgttag gaggaaagta tagggtacgt tggttgaggt
     9301 catagcaaaa acctttccaa gagcttcaga accagtgaaa agtttagtgg gatctttaat
     9361 ttgctctaaa attgctgtta aaacttgttg ctgtcttttt gtacggccgt aatctgcctc
     9421 atcatcatca cggaaacgag cataattgag cagggtcgag ccattcatct gctgttttcc
     9481 gactttaatg gtttgggttg gagactcagt ctcggtagcg tataaatcat ctccgactgt
     9541 agcttctgtt aggggacgcc cattcaatgt tgaaaattga gcatcaatcg tcaccccatc
     9601 agggaaaagc gtgtcaatcg ctgtggcaaa ggcctggaaa tcaaccaagg cgtagtactt
     9661 aatgtccaag tcaaaattat ctttcaagac ttggcgaacc atttctgccc ctttttgccc
     9721 ctcttgttct cctaactcgt aggctacgtt taacttgtta tctgtctgtt ttctaccgtt
     9781 aatcacttga ctataaccat ctatatagac caaattatca cgcatgaaac tgactagctt
     9841 cattttctta tctgagcccc cgacatttaa taccataata gagtcagttc gtgtctcaac
     9901 actgttctgg ccgattcgac catcagtacc catgattaaa atattaactc catctctagt
     9961 gtcctgacca ttaaagactt ctacttgagc tgcccgagca tcagcagttt tctttgcgct
    10021 agcatcttgg taaccacgca aaaacatgaa taccatggcc aaagccacac agaccaaaag
    10081 tgaaaaaatc accataaaaa ttcgtttaag acggagcttc cgtcttttct tttttggagg
    10141 ggaagagagt gcttgtgatt tggattgtga gcgactccgg ttcgcatagc ttggtaagtc
    10201 aacctgctct tctctttctt gttccaagct agagctacta tttcccctag caagagttag
    10261 cttttcttgc aaataggcaa actcattttt ttctctctca ttgagatagt gaatattttt
    10321 tagcaaataa tcataacgca actgctcatg atgacttaag ggattttctt tactcatctt
    10381 ctctcctttc catggtctga tattggataa ataggatagg cacccagaat tttatactgg
    10441 attccaatcg cttctaattc tttttgggca aagtggacca agtccttatc ggtataatcc
    10501 acatcgataa tgaaaaagta ttcacccagt gctgtcttga gtggacgact ttcaattttt
    10561 gtcaagtcaa ttcctcgcca agcaaaggtc gacagggcct tataaagtgc acctggaagg
    10621 ttgtcaggta atgtcaaggc caaactcatc ttttcagttt gtgcttgcaa gggaatacta
    10681 ggattttcag ctcctagaac ccagaaacgt gtgaaattgg cttccatttc ctgaatatcc
    10741 tcggcaatca gttccaatcc atattcttca gcagaacttc taggtgcaac tgctgcaaag
    10801 ggctggtctg gatgttcgga aataaaacgg gccgcataag ctgtactagc tgttacctcg
    10861 atttgagcct ctggatattg ttcatcgatg aatttctttc cttgagccaa ggcctgtgga
    10921 tgtgaaaaaa tcttttcaat cttagtatgg cctggaacca ccatcaactg ctgatgaata
    10981 ggctgaacga tttctgctac tgcttggatg tgagcctgat gaaaaagata gtccaaggtt
    11041 tcatgaacac taccctcaat agaattttca actggcacca cagaatagtt cactaatcct
    11101 tgctcataag ccttgatgac atctgtaatg ttggcaaaag cctgcaattc ctcatgagga
    11161 aaagctgtct gcacaacgtg gtgtgaaaat gatcccttgg gacctagata agcaattttc
    11221 atcttagttc ctctataatt tcctctgggc ttagcttggt cacatccaaa acccgactag
    11281 ccacttcctc ataccaagcc tgtctttctt gaaaaatagc tactagttct tccttgctat
    11341 tatttagaaa aagcggtcgc tgattgtcct tatcagctac gatacgtagg tagagggttt
    11401 caaaatctgc tttcaggtag atgttatctg tattagtctt gagtaagtca cgatttctct
    11461 gagaaataac cactcctcct ccagttgaca cgacttggtc tgtttgtagt aaatcagcta
    11521 ggacttctga ttctacctga cgaaaggctg cttctccctt ttcagcgaaa aaattcgcaa
    11581 tggacatacc taggcgcttc tcaatcagag catccatatc aaggtaatta gggtccaagc
    11641 ctcttgcaat agtcgatttt ccagccccca taaaccctaa taacacctta gccatgaatc
    11701 aagctctcca aatcatcaaa gaaactagga tagctggtat tgatggcttc tgcacggtca
    11761 agctccacct ctccatctgc aaccaagagg gctgcgatag ctgtcatcat gccgatacgg
    11821 tggtcaccaa acgtattgac tctagcaccg tgaagagctg atttcccttt gataatcatc
    11881 ccatctgccg taggagtaat atctgctccc atactattta aggcgtctgc cacaacctga
    11941 atacggtctg tttccttgac cttgagctcc tcagcatcct tgataactgt tacaccttgg
    12001 gcttgagtcg caagcagggc aataatgggc aattcatcaa tcaatcgtgg aatcaaagcg
    12061 ccaccaatct ctgttccttt caagtcagaa gactcaacag tcaaggtaga agatttagcg
    12121 actggatcga tttcagttat ttccaatttt ccacccatgg cacgaatgac atcaataata
    12181 ccggtgcgag tttcgttgat ccccacattc tgcagcacta gacgagaatt tggaacaatc
    12241 aaacctgcga ctaaccaaaa ggctgcactg gaaatatctc ctggtacgac caccttctgt
    12301 cctgtcaatt tttgtggccc ttggactgtg attttcttac tgtccacact taaatgacca
    12361 ccaaattgtt tcaacatatc ttcagtatga ttacgggtgc actctttttc gataataact
    12421 gacgccccct tagcttgtaa ggctgcaaac atcaaggctg acttgacttg ggcagaggca
    12481 attggcaact cataatgaat aggtcttagg tttttcgtcc cttttaagcg aaggggaggc
    12541 aagtctcgtt cagtttgccc tgaaatgctg acgcccattt ttttcagtgg aagggtcaca
    12601 cggtccatag gacgtttgga aagactatca tctccaaaca tctctacttc gaaatctgca
    12661 ccagcaagga cacctgaaat caggcgaatc gaggtgccag aatttcccat attaagggca
    12721 ttttgcggcg cttttaagcc agccatgcct acaccttgaa tggtaataac cccatcttta
    12781 tcctcaattt caacaccaag gtcacgaaaa acctgcatgg tcgaaagaac gtcttcacct
    12841 cgtagaatat cataaacctt ggtctcaccc tcagccaaac ttccaaagat aatggaacgg
    12901 tggctgatag acttgtcacc tgggacgcgg atactaccat gtaaatggcg aatgtttgtt
    12961 tttagtttca tactggacct catacttgca atacttttac ctattttatc ataaaaagtc
    13021 agaaattcct taaaaattcc tgactttagg atcgttcttt tcttatttca gcaattctga
    13081 aactggttca aaaacaattt tttcaatgtc agaaaggtaa atggccaatt gttgttgctt
    13141 ggtaaagaat tctgacaaga ggctatttcc ttgaatctgt ttaccaaagc cttccatctt
    13201 agcttggaag gacgcatctg gcatttgacc tgtctgtgct agtttttgaa tttcctcttg
    13261 aaaggcaaga tattctgtaa agattttgct tgcctcagca tctgctgcaa tcgcatcttt
    13321 agctgcttta acagccttgt attctggtaa tccgcgtaga ccgcgactga gttcgtttgc
    13381 actatcgtaa atatttgaca tgttcttctc cttatttgat gacgactgta tagtcggtat
    13441 tttctgttat gagatgctca gctctttcca agtcttgagc atttttaaat gaaatttgta
    13501 ggattccgtg aatatcctca cgattttcct cgttgatgtg gatgttaacc aaggaagttc
    13561 cacgtagcag ttccaaaatc cgcaggatga catcttcttc atcaggaacg tcaacataga
    13621 ggtcgtaaga gctatccaca ccaccacgct tatggatttc catggtctgg cgttgttcac
    13681 gcgcttggtt aaaaaagttc caaatttgct cttcatctcc cttactaatg gcctgaccaa
    13741 tcacttccaa acgttccttg aaatcctcaa ttctatccag aatggtctcg ctattggaca
    13801 agagaatgga ggtccacatt cctggctcgc tttccgcaat tcgggtcata tctcgaaaac
    13861 cacctgccgc aaagcgcctt gccatctcat gctcttgagc atagaccgca gtctgctcca
    13921 tgagactaga agccaaaata tgaggaaaat ggctaatctg agaagtgaca cgatcatgct
    13981 ccttggcatc aatctcgata aaacgagcat gaagacctga aagcagatcc ttcatttcct
    14041 taagcgtgtc ctgacttgtc aggcttgaag gtgtaaagat ataataggca ttttcaaaaa
    14101 gattgacatc tgccgaagca gcccctgtct tgtgactacc agccatggga tgggccccga
    14161 caaagcgaac agacttgcca gccaaatact gctccgccgc atccacaatg gttgacttgg
    14221 tcgaaccagc atctgaaata ataacgcctt ctcgcaaatc caaattggcc aactccttaa
    14281 tgaaagcaat agtttgtttg attggcaagc tgaggataat gacatctgcc aaaggagcaa
    14341 aactagcaaa atcatccgtt gcacggtcaa tcataccttc tttcaaggcg atatctctcg
    14401 aagcttgact acgattataa cctaaaattt cataatctgg atgatcgcgt ttgataccaa
    14461 gtgccataga ggctccaatc aacccaagac ctgcgatata gattgttttt gccataggaa
    14521 ctccttaata gttctttgta tagtctcggt gtttggctac cgcttctttt agttcctcaa
    14581 gattatctga tgagaatttt tcgaggattt cttgcgccag aaccgttgct acaactgctt
    14641 ccatgaccat tcctgcagct ggaagagcag tcggatcact tctctccacg gttgccttgt
    14701 aaggttcgtg ggtttcgata tccacactca taagaggttt ataaagagta ggaatgggtt
    14761 tcatgacccc acgaacaacg atgggttgcc cattagtcat accaccttca aaaccaccta
    14821 gattattggt acggcgagta taaccgtctt ctttagacca gagaatttca tccataactt
    14881 ggctgccttt acgataacca gcctcaaagc caagaccaaa ttccacccct ttaaaggcat
    14941 tgatagagac aacagcttga gccaatcttg catccaattt tctatcccat tggacatagg
    15001 aaccaagacc aactggaact cctccgacga ctgtctccac aaccccaccg atggtatcac
    15061 catcacgttt gatttggtca atatagtcct tgatttcctg ttctcgttct tggttgacaa
    15121 tagaaacttc agactgggca gctctttgct taatttcagc gactgtcaga ttttcaggaa
    15181 catctatttc cttaccacca aagaccacga catggttggc aatctccata tccagctcag
    15241 ccaagaggcg tttggctact gcaccaactg ccacccgcat ggtggtttca cgagctgatg
    15301 aacgctccaa agaatttcgc aaatcatcaa aacggtactt aatcccccca accaaatcgg
    15361 catgacctgg gcgaggatga gtaattttcc gcttgctttt aaggcggtct tcaatgtcct
    15421 ccgcagacat gatgtccagc catttctggt ggtccttatt gatgacatcc atagtaatag
    15481 gcgcccctgt cgtcttcccg tggcgaacac ccgaagtaaa gacaacctgg tcactctcaa
    15541 tcttcatacg accaccacga ccgtagccac cctgacggcg tctaagatcc tcattgatat
    15601 cctcagctgt caatggaagt ccagctggaa ttccctcaat aatagctgtt agacgggggc
    15661 cgtgtgattc tcctgcagtt aaatatctca tacactctcc ttattttacc aagtagtctt
    15721 tcatctcttc cagagaaact gggtgaatgg tcgctgaacc aagctctggc accaagacca
    15781 atttcaaggt gttaccacgc gctttcttgt catgagtaag agcctgataa agcttgtcaa
    15841 ctttccaatt ttcatagtca acaggcaagc cgaatttctg acacatctct gtgatagatt
    15901 gggtaatgcc agctggcatg aggccttttt cctcagcaac cttggaaatc tgtaccattc
    15961 ccatggcaac agcctctcca tgcatgacct tgccataacc ggcagtcgct tcgatggcat
    16021 ggccaatagt gtggccaaaa ttgaggtaaa gacgaatacc attgtccaac tcatcttcaa
    16081 ccaccatctt gcgcttcacc tgacaagaat gttcaatcaa ggtctctgca tgttccaaaa
    16141 tactctcaac agaaccattc agtcccgtca agagagccca cagttctgga tcctcaatca
    16201 agccatactt gataacttca cccatccctt caatcaactc tctttttccg agggtttcaa
    16261 gaacaagtgg atcaatcaga accccatctg gttgggcaaa ggtccccacc atatttttag
    16321 caaatggtgt gttaacgcct gtctttccac cgatagaaga atcaacctga gctgtcaaac
    16381 tagtcggaat ctgaacaaag tgaatacccc gcatataggt agaggctaca aagccagcca
    16441 ggtccccaac aacgccacca ccaagagcaa cgattccatc gctacgagtc agaccttgct
    16501 tgactagaaa ttcatagact ttctgaacag tagttaaatt ctttctttct tcaccttcta
    16561 agaaatcaaa aacagctacc tgaaaaccag catcttctag gctgagcttg accttctctg
    16621 catagagaga ggctacatgg ttatctgtca caatgactac cttttgcggt tgccagagtt
    16681 ctcgcaacca ctgaccagcc tgggccatac aacctttttc aatctgaata tcataaggat
    16741 gatgaggaat atcgattctg attttcatag gagagtctcc ctttctttat tggtattttt
    16801 ctgttaaaga ctgccaaatc tcttctgtcg gcatttcctt gcctgtccac agttgaaaag
    16861 cttctgcagc ttgatagagc aacattccca gaccattgac tgctggattg ccctgacttc
    16921 tagcccattt caaaaacggt gtttcaaagg gttggtatat gatatctgca actaaaagag
    16981 tttctggtaa gactatgttt tcaggaacag gagaggattg gccatccatg cccacactgg
    17041 tggcattaac tagcaaatcc gactcggcaa tccttgcttg cagttcagaa acatattcta
    17101 aagcacacaa atccacttta aagcctgtct gctcctgtaa cttgtctagg taaggtcttg
    17161 ttttttccat agaaacggaa cgaacaaaga ccgaaatctg actgacgcca tccaaaatag
    17221 cctgtgccaa gattgattta gccgcaccac ctgcacccag cagggtcatc tttttacctg
    17281 aaattgtaaa agaaggcaag cacttaaaaa atcccttgcc atctgtatta tatccaatta
    17341 aattgccatt ctcattgaca accgtattaa ccgcaccaat caagcgcgct tcatcgctca
    17401 gcttatccaa ataaggaatc acctgctcct tatagggcat ggacagattg atgccaaaca
    17461 tctggtagcg acgaatattg gccactgttt ctaccaagtc actcgcttca atctcccaag
    17521 ccacataagc accgttggta gctgtcgcct caaaggctct attgtggatg aagggagaaa
    17581 tagaatgctt aataggattg gcaacaactg cagctaaacg tgtatagcca tcaagcttca
    17641 tccaaaatct ccctgatttt tttcatgcta gctagagaaa tctgcccagg ggcactaacc
    17701 tcatccagac tggcaaaaga ccaactcgaa ccagtcacat ccgcagtgat acgagagacc
    17761 ttgcccacct tacccataga aatggtcaca tattcctgtt caggattgag ggttttaaag
    17821 cctcgtgtat agttcatcaa gtctaagaca tcctgctccg tgtaagccat caccgcaacc
    17881 ttaacaagtt ttggatttag gatcgtcaac tctgacaaga tttccatcat gttctcaggt
    17941 gtttcttgga aattatggta actcaaaaca agatttggga agtccagcat ttcctcaaaa
    18001 acatccttgt agctatagta ctcaaaatca atatagtctg gttgatagaa ttgcgcaact
    18061 tccttgatta gatggatata ctcttctgga gaaaggtcga tttctccacc ttcggagcga
    18121 gttcgtagcg tgaaaaccaa ctcacggcct gcgaattttt caaaaatggc tggagctacc
    18181 tgcaaaatcg cttctttagg cagatagtcg gcacgccatt caatgatgtc ggcatccagg
    18241 tacctcgtgg catccagagc ctgagcctcc tctaaacttc ttggcattac tgaaacgatt
    18301 aatttcattt actaaccttc atactaatca ccttgaggta attactactt tcatcttttt
    18361 tattataggc aaaatctgct ggaagaccat atttgtttaa aatctggtaa cttcttcctg
    18421 caaaaccttt atcaatttgt tctgtaaatt tctgacggga aacattggca gcattggtac
    18481 tggcaatgat aatccctccc ggatttaaaa tctcaagact ctgggaaatc aacttgtgat
    18541 aatccttggc cacagagaaa gtttgttttt tattccgagc aaagctaggc ggatctagga
    18601 caatcacatc gtaggtcaag tctttgcgtt tggcatattt gaaatactca aagacatcca
    18661 tgactataaa acgatgctcg tctgtgctga gcccatttgc ctgaaaatgc gcttgagaca
    18721 attctcgtga acgtttggct agatcaacag aagttgtctg gctagctcct cccatggccg
    18781 cagctactga aaaagccgct gtgtaggaaa acatattgag caaggattta cccatagcca
    18841 agccgtcaac taaactaccg cgaacctcat gctggtctag gaaaattcct gtcatcaagc
    18901 catcattcat aaagacttga tacaggacac cattttctaa aacagtgaaa aagtcaggtg
    18961 cttcttgacc ataaacatgg gcagattcat agtcaaaacc cttaaagcgg attttctcat
    19021 aagcccctaa aacctcaggg aaaacctgtc taaaggcttc tgatatagtc tgacgaatct
    19081 gataaacata agagttatac caagaaaaga cggcgtagtc gccataaagg tccactgtca
    19141 gacccccaaa gccatctccc tcttgattaa agagacgaaa ggcagttgtc aaatcatctt
    19201 gatagtaggc gtttctcttt tctttggctt ttctaaacaa cgtttcaaag aaagtttgat
    19261 tgaaggccac cttgtctttg ctgacaaacc agcccaagcc cttgttttgc tgagaaaggt
    19321 aggcagtccc aagaaagttt ccttcctgac cctgcacctc tacttcctga tccttaagat
    19381 tgacattctc aagatcactg gcttctagta aaactagccc cttagcaagc ttcttttcaa
    19441 cccttttgct gactcttatt ctattcataa ctaccattat atcaaacttt tagacaattc
    19501 tcaaaaaaga aactaccctt gcttttttac tcttctttta aaaaatggta tactagactt
    19561 cctgcaaaac taggaagtaa atgtgtaaga atcacaataa aaaatgctct tccgtcttgg
    19621 aggagcattt ctttttatca acgaaaatca aataacaaac tatgaaacta gcctcaggtt
    19681 aactgtgaga ttataggtag agaggttgaa tcagcaatat gtgtctgtca aatttagtga
    19741 caaaggtagt agaagaaaga tgaagaaata aatctgcttc aataggtatc tggaaaattt
    19801 gattttatag agaagccttt tgttacaaac tcaatatact atcaataaat aatattatag
    19861 aagcaacaat aattataatt tcacctatct gcatcattct atttcgaatt ctaaatatat
    19921 gttctatcaa gaatacttgg aacacacaca ttatagtaat taacgttttt gaaattgaaa
    19981 aatatccaaa taaataaact ataaacaaca aaaatagaac tatgttatat ttcttattca
    20041 aaacattcct ccctatattt ttgattacca atcttaatca tttacaacta cattctaaca
    20101 aactataaaa gcgtttgtcg aattgaattt atcaagcaag cgaccaacca gctcatcttt
    20161 tttctatttc tgccaatatg cgtgacaggt aataatgata gccaaaaata gcaagagcaa
    20221 gcaggaggat aagagctcct actcccaagc tgatggcaag gatagtggag agagactgaa
    20281 ccaagaatat gctcccaatt acaagggcca tcaggattgc actataaata aacaataaaa
    20341 ctatggcgac tatgccattt gaacgattca ccaggtccgt aatgctactc caattggttg
    20401 acagattttt aacgtcctta aagtaatggt ggcaagaaag gatgacactg gcaaggatcc
    20461 atgccacaat aaggtaaatc atcgaaatga tgggcaagcc tagatataga gaaagaccaa
    20521 gcaaagtcag aactggtaaa aaggactgga cagcatatat aatccaaaat ttcactttca
    20581 cataacgagc aaagtcaaag ggtaaactct taagaaaatc aacattttcc ctctccaagg
    20641 acaaggcaat tgaatgcagg ctggtgatat tgttattgac aactgctata aacactccta
    20701 caaaaaacaa gggtaaccag tatggaggat gaatgtctgg aactatctga gaatctcgga
    20761 ttttggaaat cagaccgatc atcatgagat aaggaaagaa agcacttgta aaaagcactg
    20821 taaccacgcc agtaccctgt cccaagaggg tgaggtggta gcgtaaaacc atgcggaaaa
    20881 atcccttttt agtggttgaa attctctcct tgctgcgacg ttcttttttg accttctcct
    20941 cactattaag caggatcacg tcataaaaac gaggaaggac cttctttttg gtcagataaa
    21001 gcaggaagag agttagtcct atccaagcga gcagacccaa tatggcttct gtcgaaaaag
    21061 gctccactgc tattttgtaa aagatatgaa gaggataaag gagaaatgga atgtctctaa
    21121 ctttgtcaac aatacttcca aaagtcgact gaagaaagaa gataaatatt aaaggtatga
    21181 gaactcctat cccaatcatc acattcgaaa aaatagactg atactttctg aagaccgtag
    21241 tttgagccaa gaaatgtact gccactacca tcactaaagt aacagagaca aataataagg
    21301 tcaaggacag tagcatcaaa ggcaaaccca accacagaga aggtgctagc ctaatgtaga
    21361 ggaccagaaa ataagctagg attggtacaa ttccagctag agctggcaag aggacagaca
    21421 gacctttggc cattataatc tctgattctt taaaggcata gggcctatag gaggccaggt
    21481 ccttactctc ataaaagaca ttgtaaaatg cagtgaaaga agttgaaaag gccagcacca
    21541 gtaaaatagc aaccatcgag ctaaaataaa taggtatttc ctcaaaagga aaatgaatgg
    21601 ctatattact aaaacagatg agcatcaaga gactggaaaa aatgtaagaa cttaggactc
    21661 tagcggaaac atttactttt ttcccaggat tcttagcctg cttctttcgt agattagcca
    21721 gattagcttc ttgagatgaa taaaggatat tgatatcaac taatttttta atgaccttga
    21781 gacgcatctg aaacctcctc ttttctacca gcaaggctaa ggtagatact ttccaaagac
    21841 tggtctgggt tgtcttttct caagtcctct accttaccac aataaatcaa atgccccttt
    21901 ttcaaaatag caatccgatc acagacttgc tcagctacct ctagcacatg agttgaaaac
    21961 aaaactgtct tacctttttg cgcatgctcc ttcatcattt gcttcaaatc aaaggcggcc
    22021 tggggatcca aaccagtcaa gggttcgtcc aaaacccaaa tatcaggatc agacaagagt
    22081 gccccgatga caaagacttt ctgacgcatt ccatgagaaa gagtttcaat aacctgatag
    22141 cgattttcag caaaatcaaa aacgttcaat agcctagcta gactagcctc caagtcagat
    22201 ctactcagat cataggatga ggcgatcaat tcccaaaatt cattggccgt taagcgtaaa
    22261 aataagtcag gcgagtctgc tacgtagcca atctttcgtt taatagccaa gcgattttcc
    22321 gataactcct gaccgtctac caaaatacga ccactgctgg gtgaaatgat actgactagg
    22381 gattttatag tggtcgattt tccagcccca ttatgaccaa tcaagcccat aatctctcca
    22441 ttttcaatct gcaaattgag attactcaag gcctttttat caccatacaa cttactaaca
    22501 ttttgaaatt caatcatggg acaactccta tctttatctg tattatatat cgctatacta
    22561 gcactttgat acaaaaaaat caatacttta ttttaagtag ttaaaatagt ttccttctat
    22621 cttacgcaaa cgtttgcgct aatagatact ttatgataga ataaagaaca agattgacaa
    22681 gtaagaggaa acattatgca aaatcaaaca ctcatgcaat actttgaatg gtatctgccc
    22741 cacgacggtc aacactggac gcgtctggct gaaaatgctc cacacctagc tcatctgggg
    22801 atcagtcacg tctggatgcc accagccttc aaggcaacca acgaaaaaga tgtcggctat
    22861 ggggtctatg acttatttga cttaggagag ttcaaccaaa aagggactgt ccgcaccaag
    22921 tatggtttca aagaagacta tcttcaagcc attcaagccc ttaaagcgca gggaattcaa
    22981 cctatggccg atgtggttct caaccacaag gctgctgctg atcacaggga agcctttcaa
    23041 gttattgaag tggatcctgt agaccgtaca gttgaacttg gagaaccctt caccatcaat
    23101 ggctggacta gttttacctt cgatggtcgc caagatacct acaatgactt ccactggcac
    23161 tggtaccact tcacaggtac agactatgat gccaaacgcc gtaagtctgg gatttatctg
    23221 atccaagggg acaacaaggg ctgggctaac gaggaattgg tcgataacga aaacggaaac
    23281 tacgactacc tcatgtatgc cgacctagac tttaaacatc ctgaagtcat ccaaaacatc
    23341 tatgactggg ctgattggtt catggaaacg actggtgtag ctggtttccg tttggatgcc
    23401 gttaagcata ttgactcttt ctttatgcgc aacttcatcc gcgatatgaa ggaaaaatac
    23461 ggtgacgatt tctatgtttt tggtgaattt tggaacccag acaaggaagc caatctggac
    23521 tatctcgaaa aaacggaaga acactttgac cttgtcgatg ttcgtctcca tcagaatctc
    23581 tttgaagcca gtcaagctgg cgcaaactat gaccttcgtg gcattttcac agatagcctg
    23641 gttgaactca agcctgacaa ggctgtgact tttgtcgaca accacgatac ccaacgagga
    23701 caagcccttg agtctaccgt tgaagaatgg ttcaagccag cagcctatgc cctcattttg
    23761 ttacgccaag acggccttcc atgtgtcttt tacggagact actatgggat ttcaggccag
    23821 tatgctcaag aagatttcaa agaaatcctt gaccgcctcc tagccatccg aaaagatttg
    23881 gcctatggag aacaaaatga ctactttgac catgctaact gtatcggttg ggtacgttca
    23941 ggtgctgaaa atcaatcccc aatcgcagtc cttatctcaa atgaccaaga aaacagcaag
    24001 tcaatgtttg tcggtcaaga atggactaat caaacctttg tagatttact tggtaaccac
    24061 caaggtcaag ttacaattga tgaggaaggt tatggacaat tccctgtctc agctagatcc
    24121 gtaagtgtct gggcagtcaa taccatctaa tagctcataa taaccaagct aggtccaagc
    24181 ggatttggct tttttgtatt cacaaaaaga cctacccaaa tggatagatc tttacttgat
    24241 tacaatttac ctgctactgc atccaacaat tcttggatct taggttggtt gcttcctcct
    24301 gccatggcca tgtctggttt accaccacca cgtccatcga tgattggtgc taattctttg
    24361 acaaggtttc ctgcatgaag gtcttttgtc ttgcttgcta caaggacatt gactttgtca
    24421 ccgatagcgg caactaggac aagaagatca gagtagtctt tttgtttcca gttatctgca
    24481 aaggtacgaa gggcacctgc atcggataca gacacttgac tagcaatgta acgatgaccg
    24541 ttgacttcct taacatcttt gaagatatct cctgcggctg cagctgcggc tttttctttc
    24601 aactcagcat tttctttttg aagttgacga agttgttctt gaagtccttc taccttgtga
    24661 ggtacttcct tgacttgagg tgctttcaag gttgctgcga cagctttaag agcatcctct
    24721 tgttcacgat aggcttcaaa ggcttcctta ccagtcactg ccaagatacg gcgagttcct
    24781 gaaccgattc cttcttcttt gacaattttg aagagaccaa tctcagaagt gttgccaaca
    24841 tgagtaccac cacaaagttc aatagagtag tcaccaatag tcacgacacg aacttccttg
    24901 ccgtatttct caccaaagag ggccatcgct cccatttctt tagcagtgtc aatatccgtt
    24961 tcaactgtct taacttcaag agcttcccag attttttcgt tgacttgctg ttcaatcgca
    25021 cgcaattctt cagcagttac agcttggaag tgggtaaagt caaagcgaag gaattcaact
    25081 tcgttaagag atcctgcctg tgttgcgtgg tttccaagga tattgtgaag ggcagcgtga
    25141 agcaaatgag tcgcagtgtg gtttttcatg acacggtgac ggcgattgct atcaattgcc
    25201 aaggtatatt cttggttcaa ggcaagcggt gcaaggactt caactgtatg aagggcttga
    25261 ccatttgggg ctttctgaac attggtcaca gtagccacaa ccttacctga ctcatccaag
    25321 atttgtccgt ggtcagcgac ctgtccaccc atttcagcat agaatggcgt ttccgcaaag
    25381 ataagtgagg tagttccttc tgatacagct tctacttctg cattgtcagc aacgatagcc
    25441 accaatttag aagacaattg gctagcattg tggttgaaga cactttctac agtgatgttt
    25501 tgaagagttt cattttgcat acccattgag ccacccttga cagctgacgc acgcgcgcgt
    25561 tcttgttgtt ctttcatggc tgcttcaaaa ccttcacggt ctacagtcat accagcctct
    25621 tcagcaattt cttcagtcaa ttcaactggg aatccgtatg tatcatagag tttaaagaca
    25681 tcttgaccag caatgacaga ttgacctttt tctttcaagt ctgccacaat gccttgggca
    25741 aagtgttgac ctgagtgaag ggtacgggca aatgattctt cttcgctctt aacgattttc
    25801 tcaataaagt cacgtttctc aagcacttct gggtagtagc tttccatgat ttttccaaca
    25861 gttggaacga gtttgtaaag gaaaggctcg ttgataccca atttttgacc atgcatagaa
    25921 gcacgacgga gaagacgacg aagaacataa ccacgacctt catttcctgg aagggcacca
    25981 tcaccgatag caaatgaaag agaacgaatg tggtctgcga taaccttgaa gctcatgttg
    26041 tcgccatctt ggtcataaac cttaccagac aatttctcga cttcacggat aatcggcatg
    26101 aagaggtccg tttcaaagtt ggtcttagcc ccttggataa cggccaccaa acgctccaaa
    26161 ccagcgcccg tatcaatgtt cttatgtggt aattccttgt attcgctacg aggaacagca
    26221 gggtctgcgt taaattgtga caaaacgatg ttccagattt cgatgtaacg gtcgttttca
    26281 atatcttctg caagcaggcg aagaccgata ttttctgggt caaaggcttc cccacggtca
    26341 aagaaaatct ctgtatctgg tccagaaggt cccgcaccaa tttcccagaa gttgtcctca
    26401 attggaatca agtgacttgg atccactccc acttcaatcc agcggttgta agaatcttta
    26461 tcatctggat agtaagtcat gtaaagtttc tcagctggga agtcaaacca ttcagggctt
    26521 gtcaaaagct cataagccca agtgatggct tcatcacgga agtaatcccc gatagagaag
    26581 ttccccaaca tttcaaacat ggtatggtga cgcgcagtct tccctacgtt ttcgatgtcg
    26641 ttggtacgga tagccttttg ggcattggta atacgtggat tttcagggat aatggtcccg
    26701 tcaaagtatt tcttgagggt tgctacccca gagttgatcc acaaaagagt tgggtcattt
    26761 acaggaacca aacttactga tggttctact gagtgacctt tggtcgccca gaaatcaagc
    26821 cacatttggc gtacttgtgc actagatagt tgtttcatat tgtctcctta tttacttgtt
    26881 taatgtgatt ggctttccag catttccaca tagtcaatcg cgacacagag ggaaatgact
    26941 aggtctgcat aagcgtcttc aagaaccgtt acggtatagg tagaggtcag atggaagagt
    27001 tccttcttaa tttccgcaat caactgatcg cgatcatcca gcaatttgaa attcaaatcc
    27061 cagatattgc cctcgatacg aagacctaga ttatcaaact catacttatc tcgccagaag
    27121 gtcaacttct tacgaatgac aaaactcgag ccatcccgaa gctgaatctc aaaacgagga
    27181 agcaaggtca agatttcttt actaatctca ctgacttgtt caccagccgc atcatagatg
    27241 gtaaaggttt taggaatctt aaaaaatgat ccctccacct gataggcaat ttctcccctg
    27301 tcatccttga tagcgaagcg ttcgcctcca agacgaaact tttgtttgac aagaaatgtt
    27361 ttcatcaaca cctccaaaaa tcaaaagaca agctcatatc acgaagggcg aaaaaccgcg
    27421 gtaccacctt cattcaatga acttgtcatt ctcttgttct tatgcaattg tatgattgag
    27481 tagcatgact tcctagctta gatggctcgc agcaccgcca tttctctgga ctaagacaag
    27541 tgaaaatcaa ttctcaactt tcttattata acgttttttt aagcttgcgt caactggaaa
    27601 tgatctccgt tgaattagac caattcccta catctctgat tactttttca ggatatattt
    27661 tttcttactg ccgtttttct ttttatccca aattttcata ttactaaaca cagctactag
    27721 aatatttcca aatataaagg tgcctatcac ccaatatatg gactcagttg ttaggtattg
    27781 tcgatccaag ccatccttta aatgggatag tataacagtt tggttaacaa tcataaaggt
    27841 tggccagaaa ctttttttga aaaaagtaga cattttcatt atttgttgcc gctttctgta
    27901 aggttaatac tcaataaaaa tcaaaaagca aactaggaag ctagcctcaa gctgtacttg
    27961 agtacggcaa ggcaacgctg acgtggtttg aagaatatag gcttagtata ctactaggca
    28021 agcaaataag caactagaat agaaaaagat agggttctaa aaactgactt ctattcctta
    28081 aaaacgaacc agcttgactg attcgtcttc ttacgtttat ctcctacttc cgatacattt
    28141 taaactgtag gaagaggtcg ctatatttcc ctgtccattt atggtcaaat ttctcataaa
    28201 cttctaggtg tttcatggtt tcaacatctg gatagaaggc cttatcttcc tttgtttcct
    28261 ctgggagcaa ttccttcgct ggtaggtttg gtgttgaata gccgacatac tccgcatttt
    28321 ggagagcgtt ttcaggtttc aacataaagt tgataaaggc ataggctgag tcttggtttt
    28381 taactgtttt gggaatgacc atattgtcaa accaaagatt gctggcctct gtcggtacca
    28441 cataacgtag attttcattt ttttctaaca tttggctggc ttcaccagag aaggtcacgc
    28501 cgattgcaac attattctga atcatgtagc ccttcatctc gtccgcaacg atagccttga
    28561 tatttggagt cagtttgtag agcttatcca ctgtctcttc caactgctgc ggatccttgg
    28621 agttgaggct gtagccgagg gaattgagtc ctagtcccag cacctcacgc gccccatcaa
    28681 aaagcatgat agaattctta tactccggct tccaaaggtc atcccaatgc tcaggcgctt
    28741 catctaccat ggtttcgttg tagacaattc ctaaggttcc ccagaagtaa gggatggaga
    28801 atttattacc tgggtcaaag gactggttga gaaactctgg tccgatattt tcgattcctt
    28861 caatttttga ataatcaagc ggaaccaaga ggtcttcgtc cttcatcttg ttaatcatgt
    28921 attcacttgg aatggcaata tcgtaggtcg ttccaccctg ctttatctta gtgtacatgg
    28981 cttcgttgga gtcaaaagtc tcgtactgaa cttgaattcc tgtttcttct gtaaactgag
    29041 tcaagagttc aggatcgata tagtctcccc agttatagat aaccaatttt tgactatctc
    29101 gactattgat tttactatct aaatgagtcg caattcccca caagacaagg ataatcgctg
    29161 caattcctgc taaaaatgaa tagatttttt tcatgcttgc tcctccttct cacgagagat
    29221 aaagtaataa cctacaacta ggataatact aaagagaaag actagagcag acagggcatt
    29281 gatttctaag gaaatcccct tgcgagcacg agagtaaatc tcgactgata gggttgaaaa
    29341 gccatttcct gttacaaaga aggtcacggc aaagtcatct aacgaatagg tgaaggccat
    29401 gaaataacca gtaatgatag acggagtcag gtaaggaagc atgatttcct tgaacatctg
    29461 aaattgacta gctcccaagt cataggccgc atgaatcatg tcgccattca tttccttgag
    29521 tcgaggcaag accatcaaga ccacgatagg aatggagaag gccacgtgac tagatagaac
    29581 ggtcaaaaag ccaagtgaaa acttgagttg ggtaaagaga atcaagaagc tagcaccaat
    29641 cataacgtca ggcgcaacca tgaggatatt attgagtgat agaaaggctt cttggtattt
    29701 cttacgagac tggtagatgt aaatggcacc aaaagtcccg ataatggtcg ctatcaaggc
    29761 tgataggaag gccaagaaaa atgtctgagc caaaatcagc atgagtctcc catctccaaa
    29821 catggtttca aagtgagtcc agctaaaacc tgtaaagcta ttcatatcat caccagcatt
    29881 aaaggcatag ccaatcaagt aaaagatagg caggtagagg accagaaaga ccagtcccag
    29941 ataaaggttg gcaaattttt tcatcgttct ctcctttcct tagtcaccca catggtgatg
    30001 aacatggtca ggatgagaat cacaccgata gttgaaccca taccatagtt gtcattggtt
    30061 agaaaattct gctcaatagc cgtccccaag gtgataacgc ggttcccacc aatcaaacgg
    30121 gtcagcatga agagactcaa acttgggata aagaccgact gaaccccact tcgcacaccg
    30181 ttcatagata gagggaagat gacatgacgg aaggtctccc acttagttgc accaaggtcg
    30241 taactagcat tgatgagatt attatccata tcgtctaaga cattgaaaat cggcaaaatc
    30301 ataaagggga gctcgatgta gcttgcgaca aagataaatg agaaatcagt aaatagcaac
    30361 tgctgtgaac caattccgat aaattccaag aattggttaa tagagccatt ctgaccaaaa
    30421 atcccgataa aggcataagc cttaagaaga aggttgatcc aagttggcag aataatcagc
    30481 ataatccaga gttgacggtg tttgagacgg gtcaaaaaga gggccgtcgg ataactgata
    30541 agcagtgtca caaaggtcac aatgcctgca taaagcactg agttgaaact cattttaaga
    30601 taggtcaagt tttgtgacgc aaagtaagat ttgtaatttt ctaaactgaa ctggccttcg
    30661 atgttgaaaa aggattgacc gaaaatcaag accaagggtg ccaatacaaa gagggcaatc
    30721 caaagcatgt agggtactac aaagagttta gagcttgttt tcttcatctc tttcctcctc
    30781 gattgcattg atcaaacctg cttcttgctc ttcgatttct acgtactcct caatacgagc
    30841 atcgaactct tcttcggttt cattgagacg catgatgtgg atgtcttctg gttcaaagtc
    30901 cagaccgatt tcctcaccca cgatggcctt acgggttgag tggatcatcc attcatttcc
    30961 aagttcgtca taggcgataa tttcataatg caccccacgg aagagctggg tatcgacctt
    31021 aacttgaagc ttgccttctt caggaagggt aatgcgcaag tcctctggac gaataacgac
    31081 ctcaacaggt tcatttggct tcatcccacc atcaaccgct tcaaagcgtt tgccgttaaa
    31141 ttcgaccaag tagtcctcaa tcatggtacc tggcaagatg tttgactccc cgataaaggt
    31201 ggcaacaaag tggttgattg gctcatcgta gatgtccaca ggggttccag actggacaat
    31261 ctcgccatca ttcataacga aaatccagtc actcatggca agagcttctt cctgatcgtg
    31321 agtgacaaag acaaaggtaa tgcccaatcg ttgttgcagt tcacgcagtt cgtactgcat
    31381 gtctgttctt aatttcaagt ccagcgctga caagggctca tccaacaaaa ccacacgggg
    31441 ttggttgatg atagcacggg cgatagccac acgctgacgt tgtcctccag aaagtttgcg
    31501 gatggaacgt ttttcataac cttccaactg aaccatcttg agaacttccg ctacacgttg
    31561 ctcgatttct ttcttatcaa tgttacgcaa gcgaagtgga aaggcaacat tttcaaacac
    31621 attcatatgt gggaacaagg cataggattg gaagacagta tgtacgtcgc gcttgttggt
    31681 tggaatatca ttgatacgaa caccgtctag catgatatct cctgtcgtcg catccagtaa
    31741 acctgcaata atgtttagga tagttgattt ccccgaacca gatgcaccta gaagggtgta
    31801 gaatttccct tcttccaact caaagttgat gtctttgaga accttggtgt tgctgtcttc
    31861 aaaaacttta gagacgtttt tgaattcgat aattgatttt ttcaattggc ataaattcct
    31921 tctttttcat agattaaccg atcggggctc tgtcaggtcg ccactacctc ttgcagggag
    31981 taaaaccacc tgcatacatc ttcgctacca ataggctttc accccccttt ccatgacata
    32041 gcagcagctt ttcaaataca gcttcctact tgctttcacc caagatccgg acttctcttt
    32101 caagcgtaat acctgagtgt tccttgactt tttcgataac cgattggatc aagtcctcgt
    32161 agtctttggc cgttccatct gcgacattga tcataaatcc tgcatgcttt tctgacactt
    32221 ctacgccacc gatacgatag cctttcaagc cagcttctga aattaactga cctgcaaaat
    32281 gcccgactgg acgcttaaag accgagccac aagatgggta ttccaaaggt tgcttgagtt
    32341 cacgtaggtg cgtcaagcgg tccatttcct gcttgataac ctgatgggtt cctggggcta
    32401 gggcaaattt aactgacaag acaactgcac cagactcctg aatagctgaa tggcggtaac
    32461 caaaagccaa gtctttagca gacagggttt cgatttctcc atccttggtc aagaccttac
    32521 aagactgcaa gatgtgagca atctcgccac cataggcacc cgcattcata aagacagcac
    32581 cgccaacgct tcctggaata ccacaagcaa actcaaagcc agtcaaacta tgacggaggg
    32641 caatgcgagt tgtttcaatc aagttagccc cagcttctgc ttcaatggta tagccatcaa
    32701 cagaaacgtt attgagcttg tcacacaaga tgacaaatcc acgaatccca ccatcacgaa
    32761 cgatgatatt gcttgcattg ccaagaacca tccaagggat attttcttgg ttggcaaatt
    32821 tcacaacgcg agccaactca aaacgatttc gtggaaagac caaataatca gcctctccac
    32881 ctacttttgt ataactatag ctatgcaagg gttccttaaa acggatatca attccttcta
    32941 agatttcaag cattttttct cttacagaca tgtcactctt ccttttacaa aattcattcc
    33001 attataccat ttttagagac atttgacgac cataaaaata ccttgtttgg attttgcata
    33061 agaaaaagag gttcccccct ttttatgatt ttttacaaaa gatttccttg gttccatagg
    33121 caaccagaac gagctccagt gctagaatca cttcaaccaa gactggattt gtcaaccagc
    33181 ctacttggaa aagagatggt gccagatcaa agaaggcatg caagccatag gctgctagga
    33241 gataaatcca tttcttctgg cgaacagctt ggtaaaccca aactgtcaaa agtaattgga
    33301 aaccaagcgc caagattcgc tcaaaaccaa gcaaataaat ctgccagacc gaaagtgact
    33361 gaatggtttt taacatattt tcagacagta attgcataac ctgtggattc tgagtttgaa
    33421 ctgccgaaag aacgatgtaa agattgagta aactaataag gcctagaaaa atcaactcca
    33481 agccaccatg ccctaggcca taggccaagg catctgcctt ttccaaactt ctctttttct
    33541 ccaaccattt gaagaaaaca agacgagccg tttcctcaaa aaatgctgcc atggctaggc
    33601 catagataat atagataagc ggatgatctt gcaagagggc aatactaccg tctttttgag
    33661 gatgcaaaat caagatatgc accagttttt ccaaaatctg cgaagagaca aagaaagcga
    33721 ctgcacccaa gcccaagaca gctagattaa tctggtattt ctttttggca aaccaaatgc
    33781 ttcctatcag aaaagctagc aacagcaaca tggtaataat gatatgaatg gtcattttct
    33841 tctcctattc tgccttttca atatcttttt tcatctcgtc aacattgaac ttagcaaaca
    33901 agtattgacg gtcttggact gggaaacgtt ggtccaactg gtcaactgct cccacctcga
    33961 taatgccttc cttgatgaca aaatccatga catgtccacc gaaggtcaaa tcatctgata
    34021 tgaagtgcag atggtagcct gccacactga ccccatggaa aatctcaggc gtccagaaac
    34081 caacaatagt ccccgcaaca ttgtcacgac tatattccgg ttgatgggtt gcgacatcag
    34141 caaacttggt atcgggtgtt gacttaggaa tcatacgcac atgcatatgt gaaaattccc
    34201 cccgaatctt gatagagcgg aaaagatttt ccccatcata ataagactca attcgttctt
    34261 tcaattcctt gtctgtcatc tcaaagcgct ggcggaaaat gacctctgcc tgatgcggta
    34321 ccactgcagc gtaaggaata agggcatctg gtgacacttc cccaatttct ggctggtctc
    34381 ctgacccttt ggcctgataa gccttgccat ccaagacaat caattcccca tcaatggaat
    34441 ccaaggttcc caaaccaagg tcaccatgtt ctagcaattc tcctactgtc atagtaccac
    34501 cataaaggcc agccatcaag gctccaaggg tattgtattg aaataatttc actggttcct
    34561 gcacgttctt atccattcac tttcttgtct gttattctat aaatcttact cctaagtata
    34621 ccacatttgc ccctagatgt gaacgagaga aacgctctag acattgccaa gaaggaaaaa
    34681 aaaaggtaca atgtaacaaa atcaagggag gtctggaatg aagaaacaaa gcaagtacaa
    34741 agaggtcgtt tcctatctga aaaatggtat cgagtctgga cgatttccga cgggtagtcg
    34801 cctgccttct atccgtcaac tgagccttga ctttcactgc agcaaggaca ccattcaacg
    34861 agccctgctg gaattacggc acgaacaata cctctatgcc aagcctcaga gtggctacta
    34921 tgtattagaa caagggcaac atcaagacct agaaatcgag gttaccgacg aacatgccag
    34981 tgcctatgac gatttccgac tctgtgtcaa tgaaaccttg attggccgag aaaactacct
    35041 cttcaactac tatgacaatc aagaaggatt agaagaccta agacagtcca ttcacaaact
    35101 cctctttgag caagctctct actgcaaggc taaccaacta gtactgactt ctggaaccca
    35161 acaagcctta tttatcctct ctcaaatatc ctttcctaga caagccaagg aaatcttggt
    35221 ggaacagcca acctaccatc ggatgaatcg cctcttgatt gcacaggggc tggactatca
    35281 aacgattgaa cgaggcattg atgggattga cttggaggag ctggaaggcc acttcaaaac
    35341 aggaaaaatt aaatttttct acaccattcc tagatttcac tatcctctgg gacattccta
    35401 ttctgagcaa gacaaacgat ctattcttaa cttagctgcc aagtatgatg tctatatcgt
    35461 agaggacgat tatctgggtg atttggactc caagaagggc caaaccttcc actatcttga
    35521 tacagaggag catgtcattt atatcaagtc cttctcgacc agcctttttc ctgcccttcg
    35581 tattacagca ctcattcttc caaatgctat caaagaagca tttgtggcct acaaaaatat
    35641 cctagactac gacagcaacc tcattatgca aaaggccctg tcactctata ttgacagtca
    35701 attgtttgaa aaaaatcgtt tggctcgctt gaccaatcat gaatcttacc aaaaacaaat
    35761 cgaggaaagg ataactaaaa caccttgtcc ccttcctcat tatcccctac acgatggttt
    35821 attgctagac ctgagacagt atcctaaaat cgccagtctc aaacacagtc aaccgggctt
    35881 ggacttcttt gaagaggcct atttaagtac ctgtccttat caatttgcca aggtgtccct
    35941 agacaatctg gaaaatgttt taaactattt aaaagcagaa ttggaatgac atccaactct
    36001 gctttttctt attcttcaac ttcagttaga cttgctgctt tttcaagata gctttggtaa
    36061 attccttcat ccttaagttt ttggatgacc ttgtctacca cttctttcaa atcatcacta
    36121 ttttttctaa gagcaacggc attggcgtcg ccgtccttca tcttcaagct gacagttgcg
    36181 acagctaagc cagcgttttt agcagcataa ctaagtgcaa caggctcatc catatgaaca
    36241 gcatctactt ttccagcctg caattcattg actgcttcac ccatattagt tagggaagtt
    36301 aattgagctt ttggcaattg ttccttgacc attgattctg gaacagtccc tttttgggct
    36361 gcaatattag cactttctag gctagttaaa tccttgtatt tttccacatc agccttacga
    36421 accaagaaac taatcttgtt ttcatagtat gggattgaaa aatcaaagac ttcttttctc
    36481 tcgtcagtag cactaattcc tgcaactgct aggtcagcct taccagtttg aagactggtc
    36541 aaaacattgt caaaactcat gcttgagatt tccaacttaa ccccaagttc atcagcgata
    36601 gcctgagcca tgtcgatgtc tgcaccgact acctggttct ttccatcaac caatgattga
    36661 aattcaaagg gtgcatagtc aggactggtt gccacaacta atttcccctt ttgcttaatg
    36721 gcctcaacag ctgactgaga accattagaa cctgactggc aagctactaa gaagaaactt
    36781 gcaagaaaat tacataaaac aaatatccat ttttttgatt tcataaataa acaacctctc
    36841 tgttaatttt gtataattat aacgatatcc aagttacttg tcaagtgttt tttaaatttt
    36901 tatctcaaaa atattttttc gttcaaaaaa aggagccatc agttgatttc aagctccttt
    36961 ttatacagaa ttaaactatt ttatagttcg acaatcttac ctgtttcaaa gtagacaacc
    37021 cattcacaga tatttttagc atagtcaccg atacgctcca agtaggaaat aacttggaaa
    37081 taatcacgac ccgtaacaat ggcttctgga tttttcttaa tctcttcagt cgcaaggtca
    37141 cggatagttt caaaatagtg gttaatttgc tcatccatgg aggccacccg gtatgcgtcg
    37201 tcaacagaac cattaagata aagatcaagt gctgcttcaa caacgctttt aacttcacgt
    37261 cccatttttt taatttcttc ctctacagct gggatgcgtt cttccccctt catacggatg
    37321 gttgcctggg caatggctac agcgtgatcc cccatacgct ccacatctga tacagcctta
    37381 aggacagtca agactgtacg caaatcttga gagactggtt gttggagtgc gatcatttca
    37441 aatgatttct tttccagttt cacttcgtat tcatttactt ctgcatcatc ttcgatgacc
    37501 tcttttgcca ggtcacggtc atgcgtgaca aaagcacgta ccgtacgatt gatttgtgag
    37561 agcacttctt gtcccatagc gtagaactgg ttatgtaatt tctctaaatc ttcttcaaat
    37621 tgagatcgta acatctttca tctccttatc caaattttcc tgtaatatag tcttccgttt
    37681 ccttgtgttg gggatcaagg aacatctgct tggtatcatt aaattcaatc aaatctccat
    37741 ctaggaaaaa tcctgtctta tcagagatac gtgaagcttg ctgcatggaa cgggttacca
    37801 gaagcatggt gtacttgtct tttagaccat acaaggtttc ctcaatttta ccagctgaaa
    37861 tcggatccaa agccgaagtt ggctcatcca agaggatgat tttaggacta gttgccaaga
    37921 cacgggccac gcagacacgc tgctgttgac cacctgacaa tccaatagct gaatcatata
    37981 gacgatcctt gacctcatcc cagatagagg caccttgcaa ggctttttct acggcttcat
    38041 ccagaacttg cttatcctta attccattga tacgaagccc gtagacaaca ttctcataga
    38101 tagtcatagg gaaaggatta ggttgttgga aaaccattcc gatttcctta cgtaattcaa
    38161 ccgtatctgt acgcggactg tagatgttgt gaccattgta caccacggat ccagttgtgg
    38221 tcacctctgg attgagatct cccatgcggt tgagagactt gaggagggtt gacttccctg
    38281 atccagatgg accaatcaag gctgtaattt ccttaggttg gaaagatagg gaaacactat
    38341 tcaaagcctt ctttttatta taataaacgg acaggtctga tacctgtaaa atcgcatctg
    38401 tcatacggtt tcctttctaa ccaaagtgac cagatacata gtcattggtg gactgtagct
    38461 tggcattttg gaaaatagtt gcagtcttgt catactcaat caaatcaccc aagtaaaaga
    38521 agcctgtata gtcacttgca cgagcagcct gctgcatatt atgcgttaca atgatgatgg
    38581 taaagttttt cttgagctca aacatggtct cttctagttg catggtcgca atcggatcca
    38641 aggctgaggc tggctcatcc attaagagga tatctggctt aacagagatg gcacgagcga
    38701 tacagagacg ttgttgctga ccacctgata aggtcaaggc tgacttgtgg agatcgtctt
    38761 taacctgatc ccagagggca gcctgacgaa gggaggtttc tacgatttca tctaggactt
    38821 gcttatcctt aactccagca cgttcatgcg caaaggtaat attacggtaa attgacttag
    38881 caaatggatt ggggcgttga aaaaccattc caatgtgttt acgcatttca taaacgttga
    38941 tttctggacg gttgacatca attccacgat agagaatctg cccagttact ttagcaatat
    39001 caatggtatc attcatgcga ttgagactgc gtaagtaggt agatttcccc gatcccgacg
    39061 gaccaatcaa agctgtaatt ttatttcttt caaattgcat atcaatcccc ttaatggatt
    39121 catttttacc atagtaaaca tggacatcct tagtagaaag ggctactttt tcttcaggaa
    39181 aggtaaggat atgcttctca tcccagttat atgttgacat ggcttctcct ttaggcagcg
    39241 gttaatttct tgtgtagata gcttccgaac ttacgagctc caaagttaaa aatcaggata
    39301 aagatcagga gcacagcggc agaacctgct gatacaatgg ttccatctgg aatagtgcct
    39361 tcactattga ctttccagat atggacagcc aaggtttctg cttgacggaa gatagagatg
    39421 gggctagtca cactgaggat attccagtta gaccagtcaa gagctggcgc cgattgccct
    39481 gctgtataga tcagagctgc agcttcgcca aagatacgac cagatgccaa gacgacaccc
    39541 gttacaatac ctggaagcgc ttctggaata acaacatgaa ccactgtctc ccagcgagaa
    39601 atcccaagag ccagaccagc ctcacgttgg gtatggtgaa cgtgtttcaa actatcctct
    39661 acattacgcg tcatctgagg caagttaaag actgtcaagg ccaaggcacc tgaaatgatt
    39721 gaaaatccat actcaaactg aactacaaag atcaagtaac caaagagacc caccaccact
    39781 gatggtaaag aggacaagat ttcaatacaa gtccgcacaa agttggtaac aggacctttt
    39841 ttagcatatt cagccaagta aatcccagct cccatagaaa gaggtacaga aataatcaag
    39901 gtaatgacca ataggaaaaa ggaattgtaa agctgaatgc caatcccacc acctgcttga
    39961 aaagcagaag accttccagt caagaaagac caagagatat ggggcaagcc ccgaaccaag
    40021 atatagagaa tcaaggaagc caagattgtc acaatgatgc tagcaatcgt atagaggaca
    40081 gctgttgcaa gtttatctaa tttcttagcg cgcataattt ttctttcctc tttctttcgt
    40141 aatcaattta atcacactgt taaaaactaa actcatcaag agcagtacca aggccagtga
    40201 ccagagaaca ttattattta cagttcccat gacagtgttc ccaattccca tagttaatat
    40261 agaagttaaa gttgcagctg gtgtggtcaa ggaagttggg ataacagctg agtttccgac
    40321 aaccatctgg atagctaaag cctcaccaaa ggcacgcgcc atcccaaaga ccactgcagt
    40381 gaaaatacca gaacgggccg ccttcaagat cacacgccag atagtctgcc agcgagtggc
    40441 tcccatagcg aaactggctt cacgataata acgaggaacc gcacgcaagc tatccgttgt
    40501 cataaaggtt acggtcggca aaatcatgac aaagaggacg gaaatccctg acaaaatccc
    40561 aaaaccagtc ccaccaaaga cactgcgaac aaagggaacg acgacttgca agccaataaa
    40621 tccgtacact actgaaggaa tcccaaccag gagttcaata gctggttgca aaatcttcgc
    40681 cccttttggt gatacttcgg tcataaaaac tgctgcacca atagcaaagg gggttgcgat
    40741 aagggctgag agaatggtaa cgataaagga acccaaaatc ataggaaggg caccaaattc
    40801 tttactagaa ggattccaaa ttcctcccaa aagaaagtca aagatattca caccattgac
    40861 aaagaaggtc gacaagcctt tttgcgctac gaaaaccaaa atcatggcca caaggatgac
    40921 tatcaaagaa agacaggcaa aggtcaaacc ttttcctaat ttctccagac gagaattctt
    40981 tgatggaagc aacattttct tagctaattc ttcttgattc attattgtct cccttccaac
    41041 actgtcacag ttccggcagc atctttttca accttcattt ccttaatcgg aatatacttc
    41101 aatcctttga caatcccttc ttgggtctca tccgagagaa caaaattgag aaattctgca
    41161 gccaactcat tgggctgccc caatgtatac atatgctcat aagaccacaa gggccaatta
    41221 ttgctactta tattttctgg acttaagtca tagccattca acttcatgct tttgaccgaa
    41281 tcatctatat aggtaagaga taaataagag atagctcctg gactttttga tacgattgat
    41341 tttaccgctc catttgaatc ctgctcctga ctttgcatgg cagactgacc ttccataatg
    41401 acagtatcaa aggtagcacg agaaccagag ccggctgccc gattgataac agagatgggt
    41461 aagtccttac caccaacctc tttccaattg gttacctcac ctatgaagat ttgacgaagt
    41521 tgctctgtcg ttaggttatc aacatcaacc tccttattga caatcagagc caagccagct
    41581 accgcgacct tgtggtcaac aagagcagaa gcatcaattc cgtctttttc ctcagcaaat
    41641 acatctgagt ttcctatatc aactgcccca gactgaacct gggacaagcc tgtaccagaa
    41701 cctccccctt ggacattgac cgtttttcca acatggatcg tgccaaattc atctgccgct
    41761 acttcaacca agggttgcaa ggcagttgag ccaacagccg ttatggattc tccacgatca
    41821 atccagctag cacagcctac taaacaagcc gtcagccaaa aagcgataag agacagagca
    41881 agcttttttc tttttttcac tgtttttctc ctcgaaaata attatgaata ctgtgaattt
    41941 tttaagtagt tctttatgag ttgacgcatg aattcttacc aaatttctgc gcaattaatt
    42001 atttatataa tataggctat attactcttt cctaacctcc ttttttcata tgtggataaa
    42061 atctcttgtc tatcccttcc cccattgtca cccattatag tcatttcgtg tctctttttc
    42121 ccctttttaa tgcaagggaa attactctcc ttagatgata atccaaaagc tagaaaggta
    42181 tctcaaacct ctctactctc ccagactagt ttacaactaa aaggaaaaga ttctatttta
    42241 tgagaaatct agtttacaag cggtaagaac gctaataact aaacttcttg tactctttga
    42301 aaatctcttc aaaccagtgt tttgagctat ctatggctag cttcctagtt tgctctttga
    42361 ttttcattga gtagtaaaac tacatgtaat ggcaatcaag atatcaagaa tcatcctact
    42421 aaaaaaatcc atactttcac tataacatag aataagatat ttgactagca ttttcatttg
    42481 aatctgaggc cttttggaaa ataatttttc aaaacatttc cagtaacctt tgcaaagccc
    42541 aagccattgc ctttaaccaa aacttggtac caaccatttg gcagactttc tgccagctga
    42601 acgatttctc cagccgcata cttgacaaac gcttcttggc caatttcaac cgactgttcg
    42661 acctgactcg atttcaaggc taaaccaaga gcgaaactgg gctcaaagcg tttcttctta
    42721 aaagtaccca gatgcagtcc attgcgagca atcttgagct tccctaaatc tggcaaaagt
    42781 tctggcaaga gataaagctg gtctccaaaa gtctgcaaga tacccggtag attgaccttc
    42841 aaatggtttt gggcaaattc ctgccacaag gcaacttgtt cacggctgag gttactctta
    42901 cttgccttaa atttaggagc tggattgtta cccttaaact gtagatgggc aacaaactga
    42961 ccctctccct taaactgatg agggtacatc cgagccgttt ctggcaggtc aataccagct
    43021 accattccat tgatatgctc tactggcaac aagtcaaaat catactcttc cagcaaccaa
    43081 ttgacaatct cttcgttttc ctcgggtgcc caggtacagg tcgaataaac cagacgacca
    43141 ccttcagcta acatggtcac tgcatcctcc agaatttctc tttgcaagct agcacattga
    43201 ctcggataat ctaagctcca atagtccata gcatcaggtt gcttacgaaa cattccttca
    43261 ccagagcaag gggcatcaag aacgattaag tcaaaatagc ctttaaagac cttgaccaag
    43321 cggtcggcag attcattggt caccacgaca tttgtcgctc caaaacgctc catgttttca
    43381 accaaaatct tagcccgttt gcttgaaatt tcattggaaa caagtagccc ctcccctgct
    43441 agataggctg ccagttgagt tgatttgccc cccggtgcag cagccaagtc caagaccttc
    43501 ataccaggac tgggttgggc tacttgagcc accatttgag cagcaggttc ttgcgaataa
    43561 actaaacctg tagcatgctc aggcgatttc cctgaaacct tcccatagtg gccccaaggg
    43621 gtttgagtaa tggcatcaga aaaggaaagt tgctcttctt ttaagggatt gacccgaaag
    43681 gccgaaaccg cttcctcctc aaaagaggca agaaaatttc ttgcctcatc tcctagtatt
    43741 tctttatatt tttcaacaaa tccttctgga aattgcattt aagttctttt cctttcgtaa
    43801 atataggact gaatttcctc ctgcatctca agaggcacca tcatgacagg ctgtctggtt
    43861 tgaaaatcag gagcttcacc aaaaagggtc acaacccgat agcccagact ttcccctaaa
    43921 atactagctg cggcataatc ccatggttgc agataagtga gataggtcaa caaacgccct
    43981 gacaaaatct tggcaaaact aatggccgca cttccataga cacgaacacc aagaaccgct
    44041 cggctcaaat cagccagccc ccattcattg gtttccagca taccactatt ccctgcaatg
    44101 agaaaatctc caagtggttt agttttaaaa ggagctaggg gcctatcatt tagacaaact
    44161 ggaaattccc caccaccgtg gtaacaatcc cctttgacca catcataaat cagaccaaac
    44221 tgtccctgac cattttcaaa ataagccatc ataacagcaa aatcttcctg ctgggctaca
    44281 aaattattgg taccatcaat gggatcaatg acccaaacct tgccctcttg aaccgaggct
    44341 cgcagacaac cttcttcagc acaaatctta tcctcaggat aacgggacaa aatctcacca
    44401 accaagagtt cctgaacttc tttgtccagt ctagtcacca aatctgttgg agaggacttg
    44461 gtttcaacac gcaagtcttc ctgcatatgg tcaagaatgt actgacctgc tttcttaaca
    44521 agctctttag caaattcaaa tttactttcc aagagaaatc tttccttccc ctttttcttt
    44581 ggcagcctga actgctcggt aaagtgaata gccactaacc gtttcaaatt ctcgtcccaa
    44641 acgtttctct tcgctcttgc ttggcacgac cgctttgaat cccttatagg agtccagtaa
    44701 ctttttagcc tctactttgc cttcataggc agcttcaaca tcattaaaaa aagaaagcac
    44761 tgaagcaagt tcttcagtgc tccacgacaa atctagtggg taactatact gtttgttcat
    44821 taactaatac cagctctcat tcttgcttct tttagttctt gcttacgata actacgaggg
    44881 agaaaagcac gaatctcatc ttcattaaaa ccgatttgca tacgcttggc atcaataata
    44941 attggacgac gcaaaagact aggatactgc tcaatcaaat gaagcaattc cgataccgaa
    45001 atactctcta catcaatatt caatttttga aaaatttttg aacgagttga aatgatgtca
    45061 tcagtaccat tttcggtcaa ggaaaggatg tgttgcaatt cttttcttgt taaaggactg
    45121 gtcataatat tgtgttccac aaagggaacc ttatgttttt ctaaccaggc cttagcctta
    45181 cgacatgatg tacagctcgg tgatagaaat agtgtaatca tgcttttctc ttcttatcta
    45241 tactttgcta cttctattat acaaaaaaat aaagcgcttg actagggatt tttagaaaaa
    45301 aagcctattt tttcaagaaa aataggcttt ttgcgaacga ttgacacaat tggatttggt
    45361 taattcactc ttaacgatgg ttttaaatga tatatatttt tatatatgta aattaaaaac
    45421 atctttcctt tcacttccta cgacttttca gatacagata gccaaagaag ttttcataga
    45481 gggcaaaaaa gaggaggaag gcatgaagaa agaaggtctc tggcaaaatc ataataacag
    45541 gatccttggc tggatcaaaa agccaggtat catctcccac aaagagaatt tgatggaaaa
    45601 gagtaaagaa ttggtcaaaa ccaatcaaaa ctcccccaag tccaatcatc acaggtaaga
    45661 ctactagagc caggagactt tttcgataaa gagacaaaaa gtcctttttc acaatcctat
    45721 tgacaaagac atagaaactt ggcagtgtca ctagagctac tagctgaacc aaatgaaaga
    45781 gattcttgac cactgcgaaa tggtgcagac cagctgctga cgaacgaaaa tcaggcatct
    45841 gtaagacctg actaaaagga ttggtcagat aattcatcaa gatatgaaaa ttgtattgaa
    45901 tggtttctgg ttttagatag actcgattcg ttaagtttag ccactgaatc tccataggat
    45961 agaaaatcca agccagataa atggtcagaa ggattgagag ggagaggaga aagagcatag
    46021 agccccaaaa ggtcaattta gttttcatca aaatcccact ccgcaaggct agaaaccaca
    46081 tgtgtcggtg cgattggcag gccagctact tcttctgcct tagtaaaacc tgtcgtcacc
    46141 aagagcgttg gaatgccatt gtcaatccca gcccggatat cagtcaaata attgtcccca
    46201 accatgatta actcttcacg ttccaaacct aagtgctcaa ccgccttgtc cataatgatg
    46261 gcatttggtt ttccgatata aaccggcttc actcgtgtcg ctacttcaag cagcgtaatc
    46321 agtgagccag cacctggcaa aagaccgcgt tccatcggga tgttgaggtc aggattggtt
    46381 ccgataaaat gggcaccctt ttgaatagca agagttgctg tggcaaattt ttcatagtcg
    46441 acttgccaat ccagaccaac taccacgtag gcagggtttt ccttgtcttc cacataacca
    46501 gccgccttga tggcttcctt gagtcctgct tctccgacga catagacggt cttttcaagc
    46561 cccaaatcat tcatatagtc gatggttgcc aaagtcgctg tgtagacagt cgataggggc
    46621 gtatcgatat taaaattctg agccaacatc tccttaacac tctctggagt gcgagttgta
    46681 ttgttggtta caaagagata gggaatgccc cgcttttgca attcatgaac aaaagtctct
    46741 ccagcaggga ttcggtcttt ccccttataa atggttccgt ctaaatcaat taaatagcct
    46801 ttatatttca tctatttctc cctaagcctt ttttatttct tgccaagtaa tgattgcttg
    46861 ggcattgata accccatcac ttgtaatttc atgcttgctt tccagtccag tccgttcaac
    46921 aaccgatgta atcactccac ctggtcgaac ttccttgaca tacttgaggt tgattttctt
    46981 gggaatatag tgggtcaaaa aatccgctcc catgacctca aaaatccagt ccaagtattt
    47041 actgttattg acatgaccat tcatatccaa gtcgtaaaaa cgaacatggt aatccttgct
    47101 gatcggttct tccaaggact catacttcgg tccacggata agttttttat caaaatcaga
    47161 ctggtaagga gccacaatct caggttcaac agcatggact tttcgactgt cgcggtccat
    47221 gagaacaaag gtcgccatca tatggatgag ctcctgcccc gcttcattat aaatagtaaa
    47281 gcgacggtag caaaaaagtc gattgtagct caaggcttcc gtttcgatgg taatttcttc
    47341 cgcaaaacga ggcaaacgaa ccacctcaat atcatattct gcgataatcc agaccagatt
    47401 atagtcttcc aaaatggcct tatcactaac tcccagttca atcgactgca tccctgaaac
    47461 ttgcagtgac agcaaaatca catctggaag tttgatatga ccgttcatat cagccatatc
    47521 aaaaggaatt ttcattttca tttgataagt taagcccatg atcctactcc aaaataaatc
    47581 gttctgctac agtatctccc aaaaagagac ctctctttgt catgcgaacg tggtcaccct
    47641 caatctgcat gaggccttgt tgaaccaaat ctctgacaat ttctccataa agtccagcaa
    47701 aagactgtcc aaatttttcc tcaaatcgcg ccatggaaac cccggatttc ttgcggagtc
    47761 ccaagaacat ttcttcttcc atttgctcct tttgactcag gtgatcttct gtaatacaag
    47821 cattgccttc ctcaaccgca ctgagataat gacgaatggg accatgattt ttataacgta
    47881 ctccattgac ataaccagat gcccctgcac caataccata gtattcagca ttgtcccagt
    47941 acatgagatt atgacgactt tcaaagccgg gtttggagaa attagaaatc tcataatgct
    48001 caaaacccgc tcgctccagc tctgcaatga tgtactcaaa catctccgct tctagttcct
    48061 ccttaggcag aggcaatttc ccacgtcgca tccggttcat aaagaccgta tggttttcta
    48121 aaatcaaact atacaaactc atgtggggaa tatccagtcc aatggcttta gccacatttt
    48181 cctttacttg ctccatggtc tgaccaggca gagcataaat caaatcaatg gagatgttgt
    48241 caaaaccagc cagtttcaga cgatcgatat tttcataaat atccttctcc aaatgactgc
    48301 gcccaatctt tttcaacatc ttatcatcaa aggtctggac acctagcgaa acacgattga
    48361 cagccgaatt tttcaaaaca gctatcttat ccgcatccaa atcgcctgga ttggcttcaa
    48421 tggtcaactc ttccaagaca gacaagtcca agtttttagt caagccattc agtaacacct
    48481 ccagttgcgg agccgacagg gctgtcggtg ttccaccacc gatataaagg gttgacaact
    48541 tttcaatatc ataagaacga aactcttcca gcagatgctc taaatagctg tcgactggct
    48601 gatttttgat gaagaccttt gaaaaatcac aataataaca aatctgggta caaaatggga
    48661 tgtgcacata ggctgacgtt ggttttttct gcatagtaat tattatacca caaagactag
    48721 attccagata aaaatcacca tccccagata catagtccgt ccggagatgg tgatggttta
    48781 ttcttctgtt atatcaatca caatctcttc tgagtcatca agagcttcgg ctttttcttg
    48841 ccattgttcc ttgagattat ttaattgatt ttttgatgct tctgtcgctt gaaaagcata
    48901 ggatttagct tgagcaagta tactgtccac agtgatttca cctgactcaa cctgttcttt
    48961 tgttttcaga acaaaatctg tagcctgctc cttaacttct gtcagttttt cacagacttg
    49021 ctccttggca tactccggat cttctctcaa atcatctaga aaatcttgag cctgactgca
    49081 aacttgtttg cccttatcac ttgttaaaaa caaggcaaga gctgcacctg aaaccgttcc
    49141 taaaaggatt gaggataatt tacccataag gattctcctt ttttattttt tgaaaaattt
    49201 acttgcaaga cgaagagctg acagacttgc accagtcttg agtgtttttg aaccagctga
    49261 tgaagctttc ttgctcaaga cacgcgcatg gtcattgagg tctgaaacag atagagataa
    49321 atctgcaaca gcactgaaga gtggatcaat tgtagccacc ttgacattga tatcatctgc
    49381 caagacattg accttagcca acaactcatt ggtgtgatgc aaggtcacat ccacatctga
    49441 agtcaaggtt ttaatcgtct tttctgtttc atcgatgaca cgaccaagct tttgtacagt
    49501 aatgatcaga tagaccaaaa agacaatcaa agctagggca acaagaatat atgcaacttc
    49561 taacatttag ttttcctcct ctgtaatata gtaaggggcc ttctttcgat tttgataaat
    49621 aacgatcatt ataccgagac cgataaggac aactgacagc cattgggaca ctcgaaggcc
    49681 gaagaacatg agactatctg ttcgcatacc ttcgataacc atacgaccga aaccatacca
    49741 aatcaagtaa aaggccgtga tatgacctcg tctgagactc ttccatttcc gtctaaaaat
    49801 cagaatcaag gcaaagccaa gcagattcca tagagactca taaaggaaag tcggttgacg
    49861 gtagctcccc tcaatataca tctggtcacg gataaagcca ggtagataat ccagattatc
    49921 cactgttgca ccataagctt cttggttaaa gaaattaccc caacgcccca aactttgagc
    49981 aatcataacg ctaggcgccg caatatctag aaaatcccaa gtattgatga gtttacggtc
    50041 agcaaagata tagagcacaa gaaccccagt tatcaaacca ccgtaaatgg ccaaaccacc
    50101 attccaaatg gcaaaaatct ctcctaaatt ctgactatag taatcaaatc ggaaaataac
    50161 atagtagaga cgagctccta aaatagccaa gggaaaggct actaagataa aatctaaaat
    50221 atcgtctggt atgatcttct ttctaggtgc ttctttcata gtcaaataaa ccgcaagaat
    50281 caagcctgtc acaatacata aggcatacca acgaatggct aggggtccta gttgaatagc
    50341 aattggatca agcattttgc acctcatttc gagcgattag acttgtcagt cgttcgtcga
    50401 acaaacgggt cgcatcaaag cccatttcct tggcacgata attcatggca gctgcctcaa
    50461 tcacaacaga gatattacga cctgttttaa ctggaatacg aatacgagga atggctacgc
    50521 cagaaacttc aagttcctct gcattgtttc caagacgatc aaaggtctta tgcgtatcgt
    50581 aattttccaa atagacagca agctgaacct gtgaagaatc cttgacagca ctcgcaccgt
    50641 agagactcat aacatcgata ataccaaccc cacgaatttc aatcaagtgt ttcaaaattt
    50701 cagctggttc accccagaga gtaatctcat ccttggcaaa gatatcgaca cggtcatcgg
    50761 ctaccaaacg gtgaccacgt ttgacaagct caagacctgt ctcgctctta ccaattccac
    50821 tatctccctg aatcaagacg cccatcccat aaatatccat caagacaccg tgcacactgg
    50881 tacgttctgc caaacgagaa tccagatagc tagataactc tccagataaa cgactggtag
    50941 ctgcacggct ggttaaaata gcaatcttac attctctagc agcctttaac atctcctctg
    51001 gaaccaccaa accacgggca acaatgactg ctggtgtctc aggtagaaac atttttttca
    51061 aaacttcata acggctgttg gaaggcatgc tgatcagata agaccactcc ttcatcccca
    51121 aaagttgaat ccgctctggt gtatagtagt caaaatagcc tgtcatttca agaccaggtc
    51181 gcgtaatatc cgctgtattg atttcctttt caagcaactc tggttcacca tagacaatat
    51241 ctagtctaag cttttcaatc acttctttta ctaaaaccga catcatttcc tccttcaaat
    51301 gagttcttct ctctattata tcaaattgta ggaggaagtt tcagattttt gcaggctttg
    51361 gagtatttat ttaaaagaaa aaggactaga tttctctagc ctttcattgc aattagaatt
    51421 ttttacgttt acgagctact tctgatttac gtttacgttt tacagaaggt ttttcataga
    51481 attcacgttt gcgtgtttct tgaagagtac cagctttagt aaccgcacgt ttgaaacggc
    51541 gaagtgcgtc gtcaagagat tcattcttac gtactactgt tttagacatt tttttcactc
    51601 ccttcaagtt caatatctat ttcattctac acgtaaaagg aataattgtc aagcaaaaat
    51661 gcggtttaat tttgattttt tcttccattt atacaagagt tgaaagcgtt caatagaaca
    51721 ttgctttttt atttttcgag taagctaagc gcttcagcat ctgcgatgat ggttacatca
    51781 gggtgatttt ggaggctact tgcaggtagg ttctcagtca ctgggccaga tactgttccg
    51841 gcaatggctt ctgctttcga ctcaccgtaa gcaaaaagaa taatagactt ggcatccaaa
    51901 atgtttttaa tccccattga aatagcttgg gttgggacgt cttcaatctt ggcaaagaag
    51961 cgtgcattgg cttcaatagt agactggtca agttctacta gatgcgtttg actgtcaaat
    52021 ggagtaccag gctcattaaa gccgatatgc ccattgcgac cgattcccaa gatttggagg
    52081 tcaactggat ggtcagccaa aatttggttg tagcgttcaa cttcagcttc agcattgtcc
    52141 ttaacaccac gaggcaagaa actttcttta aatggttttt ggttgaacaa gttttcttgc
    52201 atgaagtaac gataagactg tggattgtcc ccatcaaggc ccacatactc atcaaggttg
    52261 acactggtta gatttgaaaa atcaaggtta ctctcaacaa tttccttgta aaattcaagt
    52321 gggctacttc ctgtcgcaag tcctagagtt tgagctccat tagccaattt ttccttcaaa
    52381 atctcaaaag caacttttcc accttgaact tggttttcaa ctttaataac tttcatcttt
    52441 tcatcctcca tttctatcta tatttattat atggtataga ccaatttttg tcaagtgaaa
    52501 acgatttaat ttctaaaaaa agagcgtcca aacttgaaac gtgttataat ggataggatt
    52561 agaacttaga aagaatgaac agatatatga atacagctga ttttgatttc cacttgccag
    52621 aggaattgat tgcccaaacg ccccttgaaa aacgtgatgc ctccaaactc ctcatcgtca
    52681 accgtgagac aggagaaatg caagataaac acttccactc tattattgat atgctggaac
    52741 ctggtgatgc ccttgtcatg aacgacaccc gagttctccc tgcccgcctc tatggtcaaa
    52801 aagtggagac aggaggtcat gtggaacttc tcctccttaa gaacactagt ggagacgagt
    52861 gggaagttct ggctaaacct gccaaacgcc tcaaggtcgg tactcgtatc agctttggtg
    52921 atggccgcct cagcgctgtc gttacagaag aattgaccca cgggggacgc attgtccgct
    52981 ttgaatacca aggaattttc ctagaagtct tggaaagtct gggagaaatg cctctgccac
    53041 cttatatcca cgaaaaatta gatgaccgtg aacgttatca aaccgtctac gccaaggaaa
    53101 gcggctctgc tgcagcaccg actgctggtc ttcacttcac caaagaactg ctggcagaaa
    53161 tccaagctaa gggtgttcat ctagtctatc tgactctcca tgtcggactc ggaaccttta
    53221 gacctgtttc tgtggataat ctggacgaac acgaaatgca ttcagagttc tatcaacttt
    53281 ctgaggaagc tgctgccacc cttcgctctg tcaaagaaaa tggtggtcgc gtcatcgctg
    53341 tcggaaccac ttctatccgc accttggaaa ctattggttc caagtttgat gggcaaatcc
    53401 aagcagattc tggttggacc aatatcttta tcaaacctgg gtatgagtgg aaggtcgtgg
    53461 atgccttctc aaccaacttc catctgccaa aatcaactct ggtcatgttg gtttctgcct
    53521 ttgcaggccg tgaattagtc ttagatgcct accaccatgc gatccaagaa cactaccgct
    53581 tcttcagttt tggtgactcc atgtttattt attgagaaag aatttctcta aatcttctaa
    53641 taccaataaa tcgctaagat attatttcaa agaacatcta caattgaaac tctagctagc
    53701 tgtagaagag gcctagtaca ttgaaattaa aatgcttccc cctagcttcg aaaatattgc
    53761 catagattgc gttgactctc caaattgatt catctatatt ttatttcagc ttcctatatt
    53821 ttcttcgctg tttgtaaatc aaaatgcaag acacatgagt agcaccatat ttgttactct
    53881 tatctgtcct ctcaagagac tattatgagt tatttcagaa tcattcacta ctttgaccct
    53941 gactctcctt agtctcaaaa tcaaagactt atactcttca aaaatctctt caaaccgcgt
    54001 caacgtcacc ttggattata tatgtgactg acttcgtcag ttctatctac aacctcaaag
    54061 cagtactttg agcaacctgc gactagtttt ctagtttgct ctttgatttt cattgagtat
    54121 taaacaaaaa gtgaacaaag ctgaattcta atgtacagaa gactaggctt gttcactttt
    54181 ttatagtcgc tataagatga ccttatctat agctttttat atataattat atattcagac
    54241 atactattat caattttgtc gcagggagga atctgttaac gcacccattc accattatca
    54301 ttgactctat agccatctat acttgtattg accgctaact cacccgatgc atttacataa
    54361 taccatttac caccaacttg gaaccattga ttgactttca tagaaccatt gctgttgagg
    54421 tagtaccatg aaccattaac ttgtacccaa cctgttgcca tggagccatc agtattataa
    54481 aaataccaca taccattttc ttgtttccag cctgttgttg gagcaactgc tttagctggt
    54541 tctactgcta catctgttcc ttggttagat gtaacagata caggatatga aggaatagat
    54601 gattgctcag gaacaacaac tttttcaggt tctctcgtcc ctctccttat acgtcttttt
    54661 accatctctt tagtaatttg acgagaagta gtttcttcaa ttgttccatc acgttcatct
    54721 acagcataga ttgtagtaag agtaatttta ccaatttctc ctacttcttg acctttatca
    54781 agagttgggt catcgagata ttctgtttcg attggaattt cttggacaag aacttggggc
    54841 ttggttcctt ttttaacaac tcttgtttga gagtcttctt tttgacttaa agtactctca
    54901 gttacttgtc cactctttcc atctacatca taagttatcg ttgtaactgt tttcccattc
    54961 tttcctagag taatctcttg ctcctgtcct gcagaaaggt cattgtctgc ttcatattca
    55021 gtagtaaatg gaacaagaac ttcttcaacc ttgcttttag ctggaacttt gataactgta
    55081 tccgtggctt cttttctatc aacagtaacc tgttcggtaa cataaccagt ctctggatta
    55141 acatcgtagg tccttgtcgt agttacatag ccatcctctc catcaattgt aacaggattt
    55201 tcactacggt cttttgtttc atctttttca taacgaattc gcgtacttga aattttcttg
    55261 gttactacct taggtttagt cgctactttt acaataatat ccccattgtc agcgtcatca
    55321 tactctattc cctcttcttt atctctagta tcatctctga catattgaat cccatcagca
    55381 gcatgaacaa aacttgtatt cagattcctc ctaaaaataa agttagcccg attaccgcag
    55441 aaccaaaaat ctttccgagt ttacgtattg catagcgctt attagtatta gattttgcca
    55501 ttacatccta cttctagtat agcatctttt ctatcaaacg ttaaacaata tactttatat
    55561 ataaaataga cttagaatga tatattgatt actgaactaa cactttaact atatcgtaat
    55621 caatctcata tataaaggat tgcagacatc ttatctaaat acatgctaat atatttagat
    55681 acaaacattc caacttgata attttcactc atctttcatc attccttata caactatgca
    55741 gtataaatag aatagttttc tcatcagaat gagactattt taatattaga taatttgata
    55801 gaaaaaacat gaataaaatt ggttgaattt aattccctaa ctcgatagag gattctattt
    55861 taaatttaac aacagctagg attacactat aaaaagtaca ttaccacctg ttcggctgga
    55921 gaatctagtc gattagctcc ctcttagtta caagcttaaa gcgatttttt aactaacact
    55981 aaaccagatt aaagaaggaa ctagaacatc tgtcttgtac taatcaatat gctattttaa
    56041 agtttcaaat aaacttggaa tgctaattat tatatttaca ataaatagtt gacttcgata
    56101 gaaacagaaa atagaattca acattcttcc ctacttatac cataataaat aagatccgca
    56161 agatagcctt ttctctctac accattaaca atggtttgta gataggacat tccagccttt
    56221 tccatgacac gacctgaagc tgggttgaga ctggcataac gtgctctgac cttttgaaaa
    56281 cctgcttgag taaaacaaaa gtccaagata gctttcaaag tctctgtcat cataccattt
    56341 ccccagtaag ccttgcctaa cacatagcca atttcacagc ttaaatcagc ctcgtctatc
    56401 ttaacaatgc tgatatctcc tatcacttgc tctgggtttt cttttagaca aatggcccat
    56461 ttataatagt tgagattagt ataggaagca acccaattgc aaatcgagtt tcgagtgatt
    56521 tcgacatcag gatggggatc ccaggtaaca taggtcagat tctcagcgga tgaagcccaa
    56581 ttttgaaaca tggcttctgc atcactctcc acaaatcttc ttaaaatcaa acgttctgtc
    56641 tgtaatattt gcgtaccgat agatttcatg atgctacctc acttccttat ttctatactc
    56701 gtagtaaaaa ggctcaactc agtaacagct agaaaacgag tttgtcttct aatttcttga
    56761 cgcagttgct gcctggtttg aaatgcgctc tagcaagctt tttcaaacct agtcatcgtt
    56821 gcaggggtaa gacgatgaaa tcgaactctt cgagttactg aatctgcctc attttcttat
    56881 ttctaaactc ggggttcaag atcccccaga ccttctctca ctttcttatt tcaagatgag
    56941 aggctgaaaa cctccagtgg aggtttttct tgctttttaa tttcagggca agaagctaaa
    57001 aagtcccccg gaccttcttc gctttctcat ttctaggctc agggtaaaaa cctccaatgg
    57061 aggtttttac tcccaaaagt catcaaatac agtgatgggt aagtggcgtt tgtgttggcc
    57121 tttgtgccac cagttttcaa tggtcgcttg agcttctggg ctgattgttt tgccttctag
    57181 gtagtcgtca atctctgcgt aggtgactcc aagtgcgact tcgtcagcta ggcctggttt
    57241 atcttcttct aggtctgccg ttgggatttt ttcataaagg gctggctctg cgccaagttt
    57301 ctgcaagagc tgttttcctt ggcgtttatt gaggcggtaa agagggagaa tatccgcacc
    57361 gccgtcacca aacttggtaa agaaacctgt gatattttcc gcggcgtggt ctgttccaat
    57421 gaccgctccg ctatgggaac cagcaagggc atactgagca atcatacggc aacgtgcctt
    57481 gatattcccc ttgttgaagt ctgaaacagg actacctgtc gcttcaactg cagctgtcat
    57541 ggcatcagct gattccttga tattcacaac caagctgaca tctggctgga tgaaggctag
    57601 agctttttga gcatctgctt catcagcttg cactccgtat ggcaggcgga cagcgataaa
    57661 tttgtagctg tcgtctcccg tttcagatcg cagttcttcc atagctaatt gcgccaaacg
    57721 ccctgccaag gttgagtctt gtcccccaga aatccctagt acaaaggttt ttaggaaggg
    57781 atgttttttc agatatcttt ttaagaaatc aatagaacga cggatttctt cctgggcatc
    57841 aatcactggt ttgacaccca gctcttggat aatcgtttct tgcaaactca ttcttcttct
    57901 ccttcaccaa gggcttcctt gcgcatctta tcaatcaagt ccatcttatc ttgccataca
    57961 tcacgagcca aatccactgg atagtgctgc ggattgagca cacgcttata ctcatcccac
    58021 aacttgtcaa attccttacg ggcataatcc tgaatgtcag tcaaactagg caagttgtaa
    58081 actaatattc cttctttgaa gatatccacc aagagaggaa cggcatcaaa attacgaacc
    58141 gtcttcttga tgtatgtata ggtcggatgg aacatcttga tttctgtcat gtcgctaata
    58201 tccacaccat cataagtgat atagtcgcct tctgacttgc ctttttcacg actggtaatg
    58261 cgccacacct gcttcttacc tggcgtagag actttttccg cattattaga cagcttaatc
    58321 gtattgcgca tctgaccagt ttcatcttcg attgcaacaa tcttgtaaac tgcaccaaga
    58381 gctggctggt cataggctgt aatcagcttg gtacccacgc cccagacatc aatcttggcc
    58441 ttttgcatct tgaggttgag gatagtattt tcgtccaaat cattagaagc ataaatctta
    58501 gcctctgtaa atccagcctc gtccagttgt tgacggactt tcttagaaat gtaggcaata
    58561 tccccagagt caatccgcac acccataaag ttaatctgat cacccagctc acgcgccacc
    58621 tgaatggcag ctggtacacc gatgcgaagg gtgtcatagg tatccacaag aaagacacaa
    58681 tttttgtggg tcgcagcgta agccttgaaa gcttcatagt cattgccata aacctgtacc
    58741 aaggcatggg catgggttcc caaaacagga atgtcaaaga gcttacccgc acgcacgttg
    58801 ctggttccat tggcgccacc aatcaccgct gcgcgtgttc cccagatggc cgcatccatt
    58861 tcttgagccc gacgtgtccc aaactccatc aagggttcat cttcgataac cgaacgaata
    58921 cgagctgcct tcgtcgccac caaggtctgg tagttgacga tgttcaaaag agccgtttcg
    58981 accaactgac attgggctag aggtccttcc acctgcacaa tcggttcatt agcaaaaacc
    59041 aaatcccctt cttgggcaga acgaacggtc aactccaact tgaaattgcg aaggtaattc
    59101 aagaacgccc catgataacc aagcaactcc aaataggcta tatcactatc tgaaaaacgc
    59161 aagccttcaa gatagttcac aattctttcc aaacctgcaa aaaccgcata gccgttctta
    59221 aaaggctgtt ggcggaaata cacctcaaag accgccttct tattgtgaat cccttggtca
    59281 aagtaaacct gcatcatgtt gatctggtac aagtccgtgt gcaatgtcaa actatcatct
    59341 ggatacatac ttttcctact tccttagcta gaaacccatg aaaattttca agaactttca
    59401 tgtattccaa taaattagta ctattatatc acattttagc tggattgaga aaagagtaac
    59461 aagctattct ccactctcca attcatccat atcttgttca aattttttct gagcccattc
    59521 gccatagctc ttaagaccaa gattgccaat aaagatccac ggaaggtaaa tgatataagt
    59581 aatgacccaa gcagacaggt atttaaaatt caaaggattg tgctgataaa tttctatgtt
    59641 gaattgataa ttctgcaaca tcaaaagagc cgtaatagtc aaggttagga aaaaacaacc
    59701 caaaatcgta aaatgaaaac gactatagta ggtcactccc agataacggg cacgattgaa
    59761 aaagtaaaat gtccctatga tgataacgat tagcagcata ttagaattaa aaaggcttgg
    59821 tgctaatact gaaatgatat aagataggag cgacaaagca atgcagatat agaaactttc
    59881 agagcccgct ttattgaaca gttgttcttc tctttcgtct agtaattgat aataataaaa
    59941 tctatttttc atcttcttcc tcccaaaata gttggtctag ggttttccct aaacatctgc
    60001 aaatagactg gcagagcgag agactgggat tgtattttcc cgcctctatt aaaccaatag
    60061 tctggcgtgt caccccgaca gcctctgcca gttgaccttg tgttaaatca cgctctaccc
    60121 gagctaattt taattttaaa tttttagcca ccttcgtcct ccttatagtt ttaatactca
    60181 tctactctta aaaaatccaa aaccaacaca agctatcagc tatttattat aaccccatta
    60241 atttgcattc cagtattatc ttcagccgaa aatcagtatt ttaggttgtt tgaaataaac
    60301 ttcctagttt actcttttat ttttatttag tattagcttt agtaagatct tttaaacgaa
    60361 tttttattgc ttatatttct tgtttagttt agttggtttc atatcactat tatataatgc
    60421 ttttggaaat gagcctagta taagtcaaaa acgtgttgaa tagtgaaagc aggagcatac
    60481 caagatgact gattttttac tgtattttag gtatgcaaaa taatactaaa tgaaactaaa
    60541 atgaatactt cttgcttttc ttgagagtga aaaagtacaa taaaatgatt gtagtgatta
    60601 ccacaagata ctgactaata gacatcgtat ttgaagccac aaatacaggt aaagaataaa
    60661 aaggaagaag ttcaattgct ttgataaaca aatcattact agtattcatc atcatcgtat
    60721 ttaatatatt agggataaag agtagtaaag ctactaaaat accaaatacc aagccacttt
    60781 tcaatttgta taaatagaaa atgtaagata atagaaaata aaacaggact aacaaaattg
    60841 tattgactac aatagctact ataaaatcta atcctaaatc acctggaata cccaatttac
    60901 ttactatgac tagtaacaca atgccattca aagcataaat aatggaaact gagatggcat
    60961 atagaaaatt agacaagacg taaatcatcc gattcttctg ttgattataa aacaaactta
    61021 ccgtattgtg ggaaaaatct ctactaataa ctcgattagc atgtataaca gccattaaca
    61081 taccgagcat agcataaaag tttgaaatat gcttaatacc aagcgatgtc tcttgagtct
    61141 ttagaataaa gaatgtaagc aatatcggcg gtataaacga gataagcaaa ctgagatata
    61201 ttacgcctga tgaatataaa tttcttatat tttccttaag aaaattcaat ttatttaatt
    61261 tcatgattat aaccttcctt tattttgaac gatttaagta aatatcttta agcgtctctt
    61321 ttttagtttc aaaatcaact actttaatag agttttcgtt aaaaaattta aaaagctcac
    61381 tactttgaat attcccagac atagtaattc tcagtccctc ttcctgaaca atatccccaa
    61441 attcttgttt ggtaatgaaa atgtctctat ctgtagctga tgaaaaagct atctcaaaca
    61501 agaaattatg actatctttt cctacttttt gaaatgtcaa aagcccgctc tccaagaaaa
    61561 gaaccctctc acaaatttct tcaatgtctt ctaatttatg actcgatatt aaaattccca
    61621 cgttttcatt taaagctaat ttttttagaa ccgctaaaac tatttgtgat gattcaatat
    61681 ctaaaccatt agtcggttca tctaaaatca atatatcagg tttcgtaacg agagttagaa
    61741 gcaaagctaa tttttgtttt gtacccaaag aataggtctt tactttttta ttaatagact
    61801 gagtcaaatc taactcttgg atcaaacttc taaatctttc ttgattgtag tcaacaccat
    61861 ataaatttga caaatatttt aaattctcta aacctgtttt agataaaaat aattttggtt
    61921 cttcgattaa atacccaata ttatcactgc ttataatatt acctgaagtc ggttgattat
    61981 tctgaacaag aattttcatc aacgtactct taccaactcc atttctccct actagaccaa
    62041 caatttcacc cttgttaagt gcaaaattta tatctttgag aatgattgaa tgaccataat
    62101 gcttacttac atttataact tacatttttt attcctccat taatattcat ggtttgctct
    62161 ttgattctta ttgagtttaa aaagttgcgc ctctttttaa caacattata tcatatatct
    62221 aacttaatgc aatatataaa tgtcattttg taaaatttta ttaacaaaaa actctctaca
    62281 acaaaataat agagagtttt ctgcttatta atttttttca aaatatctaa acatcacttc
    62341 tttgtttaat ttgataggct ttgataccta agctccgact ttatcactta aaaaataaaa
    62401 aaggacagct aatctcttgc gcatcaaggg atttcgccat tctttaatct cgtttaagtg
    62461 ttgtatatgg agctttgcat aattttttaa aactaaacaa ctacattaaa c
//
LOCUS       DAVAGB010000005        62330 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVAGB010000005 DAVAGB010000000
VERSION     DAVAGB010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 62330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62330
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.005"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(383..1243)
                     /locus_tag="VQO19_000375"
     CDS             complement(383..1243)
                     /locus_tag="VQO19_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HET1348691.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(1259..2536)
                     /locus_tag="VQO19_000376"
     CDS             complement(1259..2536)
                     /locus_tag="VQO19_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET1348692.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(2529..3080)
                     /locus_tag="VQO19_000377"
     CDS             complement(2529..3080)
                     /locus_tag="VQO19_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET1348693.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(3096..4355)
                     /locus_tag="VQO19_000378"
     CDS             complement(3096..4355)
                     /locus_tag="VQO19_000378"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET1348694.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            complement(5364..5522)
                     /locus_tag="VQO19_000379"
     CDS             complement(5364..5522)
                     /locus_tag="VQO19_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348695.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(5532..6842)
                     /gene="obgE"
                     /locus_tag="VQO19_000380"
     CDS             complement(5532..6842)
                     /gene="obgE"
                     /locus_tag="VQO19_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HET1348696.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYSRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEDFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            complement(6906..7040)
                     /locus_tag="VQO19_000381"
     CDS             complement(6906..7040)
                     /locus_tag="VQO19_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HET1348697.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            complement(7099..7275)
                     /locus_tag="VQO19_000382"
     CDS             complement(7099..7275)
                     /locus_tag="VQO19_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET1348698.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            complement(7306..8631)
                     /locus_tag="VQO19_000383"
     CDS             complement(7306..8631)
                     /locus_tag="VQO19_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET1348699.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRIIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            complement(8647..9690)
                     /gene="cpoA"
                     /locus_tag="VQO19_000384"
     CDS             complement(8647..9690)
                     /gene="cpoA"
                     /locus_tag="VQO19_000384"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HET1348700.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            complement(9805..10134)
                     /locus_tag="VQO19_000385"
     CDS             complement(9805..10134)
                     /locus_tag="VQO19_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET1348701.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            complement(10148..11257)
                     /gene="rpoD"
                     /locus_tag="VQO19_000386"
     CDS             complement(10148..11257)
                     /gene="rpoD"
                     /locus_tag="VQO19_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HET1348702.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            complement(11260..13020)
                     /gene="dnaG"
                     /locus_tag="VQO19_000387"
     CDS             complement(11260..13020)
                     /gene="dnaG"
                     /locus_tag="VQO19_000387"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HET1348703.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYQAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEEFERLISQKRRME"
     gene            complement(13132..13869)
                     /locus_tag="VQO19_000388"
     CDS             complement(13132..13869)
                     /locus_tag="VQO19_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1348704.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKSKNENL"
     gene            complement(13866..14732)
                     /locus_tag="VQO19_000389"
     CDS             complement(13866..14732)
                     /locus_tag="VQO19_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET1348705.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            complement(14801..15805)
                     /locus_tag="VQO19_000390"
     CDS             complement(14801..15805)
                     /locus_tag="VQO19_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET1348706.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     misc_binding    complement(15918..16135)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(16218..18914)
                     /gene="ppc"
                     /locus_tag="VQO19_000391"
     CDS             complement(16218..18914)
                     /gene="ppc"
                     /locus_tag="VQO19_000391"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HET1348707.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(18934..20163)
                     /locus_tag="VQO19_000392"
     CDS             complement(18934..20163)
                     /locus_tag="VQO19_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET1348708.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(20319..20621)
                     /locus_tag="VQO19_000393"
                     /pseudo
     CDS             complement(20319..20621)
                     /locus_tag="VQO19_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(20726..20973)
                     /locus_tag="VQO19_000394"
                     /pseudo
     CDS             complement(20726..20973)
                     /locus_tag="VQO19_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335280.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
     gene            complement(21255..21864)
                     /locus_tag="VQO19_000395"
                     /pseudo
     CDS             complement(21255..21864)
                     /locus_tag="VQO19_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000662948.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
     gene            complement(21922..22350)
                     /locus_tag="VQO19_000396"
     CDS             complement(21922..22350)
                     /locus_tag="VQO19_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET1348709.1"
                     /translation="MDGITKDFIKTAKLMKQLWPQLTDKEAIDEVKKYTNGKNTAIFT
                     EVEGDTIVGLALCSLRFDYVEGCKYSPVGFLEGIIVDEEYRLKDIAKNLCTKCEEWAK
                     NKGCKEFASDCTLTNTDSIRFHLNIGFQEANRIIHFKKKL"
     gene            complement(22406..22708)
                     /locus_tag="VQO19_000397"
     CDS             complement(22406..22708)
                     /locus_tag="VQO19_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348710.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKLVSINE"
     gene            complement(22983..24722)
                     /locus_tag="VQO19_000398"
     CDS             complement(22983..24722)
                     /locus_tag="VQO19_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HET1348711.1"
                     /translation="MELSAIYHRTESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELE
                     NQLVISPDGFVIF"
     gene            complement(24885..25793)
                     /locus_tag="VQO19_000399"
     CDS             complement(24885..25793)
                     /locus_tag="VQO19_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HET1348712.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKQGILA
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVIANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKVEVFSKPKED"
     gene            complement(25905..26759)
                     /locus_tag="VQO19_000400"
                     /pseudo
     CDS             complement(25905..26759)
                     /locus_tag="VQO19_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
     gene            complement(26817..27575)
                     /locus_tag="VQO19_000401"
     CDS             complement(26817..27575)
                     /locus_tag="VQO19_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET1348713.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEAVLYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            complement(27637..27825)
                     /locus_tag="VQO19_000402"
     CDS             complement(27637..27825)
                     /locus_tag="VQO19_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HET1348714.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(28147..28713)
                     /locus_tag="VQO19_000403"
     CDS             complement(28147..28713)
                     /locus_tag="VQO19_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348715.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(28981..30660)
                     /locus_tag="VQO19_000404"
     CDS             complement(28981..30660)
                     /locus_tag="VQO19_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HET1348716.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEDCIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIDLDNDEQVECVSLLEKRS"
     gene            complement(30752..30913)
                     /locus_tag="VQO19_000405"
     CDS             complement(30752..30913)
                     /locus_tag="VQO19_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348717.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(31597..31910)
                     /locus_tag="VQO19_000406"
                     /pseudo
     CDS             complement(31597..31910)
                     /locus_tag="VQO19_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(31876..32265)
                     /locus_tag="VQO19_000407"
     CDS             complement(31876..32265)
                     /locus_tag="VQO19_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET1348718.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            complement(32653..33447)
                     /locus_tag="VQO19_000408"
     CDS             complement(32653..33447)
                     /locus_tag="VQO19_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1348719.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLVKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVNS"
     gene            complement(33447..34454)
                     /locus_tag="VQO19_000409"
     CDS             complement(33447..34454)
                     /locus_tag="VQO19_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET1348720.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGVLLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(34454..35461)
                     /locus_tag="VQO19_000410"
     CDS             complement(34454..35461)
                     /locus_tag="VQO19_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET1348721.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(35451..36476)
                     /locus_tag="VQO19_000411"
     CDS             complement(35451..36476)
                     /locus_tag="VQO19_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HET1348722.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGLSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIRIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(36597..36866)
                     /locus_tag="VQO19_000412"
     CDS             complement(36597..36866)
                     /locus_tag="VQO19_000412"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348723.1"
                     /translation="MTLRTEDQVRDYAREVLGFNEVEENINQGTGQITTFNQLGFKGY
                     SDKPDGWYLPKNMNDVAIILETKSEERDISKQIFIDELMKNIDII"
     gene            complement(36870..37088)
                     /locus_tag="VQO19_000413"
     CDS             complement(36870..37088)
                     /locus_tag="VQO19_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET1348724.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(37379..37612)
                     /locus_tag="VQO19_000414"
     CDS             complement(37379..37612)
                     /locus_tag="VQO19_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HET1348725.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDKEVLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAVYSIHFNNGYCN"
     gene            complement(37826..39457)
                     /gene="rlmD"
                     /locus_tag="VQO19_000415"
     CDS             complement(37826..39457)
                     /gene="rlmD"
                     /locus_tag="VQO19_000415"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET1348726.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKNS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSEQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMNLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(39531..40505)
                     /locus_tag="VQO19_000416"
     CDS             complement(39531..40505)
                     /locus_tag="VQO19_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HET1348727.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(40579..41193)
                     /gene="pmp23"
                     /locus_tag="VQO19_000417"
     CDS             complement(40579..41193)
                     /gene="pmp23"
                     /locus_tag="VQO19_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HET1348728.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     QDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(41193..42167)
                     /locus_tag="VQO19_000418"
     CDS             complement(41193..42167)
                     /locus_tag="VQO19_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HET1348729.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDVSRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(42175..43431)
                     /locus_tag="VQO19_000419"
     CDS             complement(42175..43431)
                     /locus_tag="VQO19_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HET1348730.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYISLIEPGDTVMGMDLASGGHLTHGAPVSFPGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(43493..43924)
                     /locus_tag="VQO19_000420"
     CDS             complement(43493..43924)
                     /locus_tag="VQO19_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET1348731.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(43926..44525)
                     /locus_tag="VQO19_000421"
     CDS             complement(43926..44525)
                     /locus_tag="VQO19_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HET1348732.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFDQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(44512..45351)
                     /gene="prmC"
                     /locus_tag="VQO19_000422"
     CDS             complement(44512..45351)
                     /gene="prmC"
                     /locus_tag="VQO19_000422"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HET1348733.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALDLASENAKNQNLQ
                     IFFKKSDCFTEISEKYDIIVSNPPYISREDESEVGLNVLYSEPHLALFADEDGLAIYR
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTFKDQFGQDRMVVVDD
                     GQD"
     gene            complement(45351..46430)
                     /gene="prfA"
                     /locus_tag="VQO19_000423"
     CDS             complement(45351..46430)
                     /gene="prfA"
                     /locus_tag="VQO19_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HET1348734.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASTR
                     DTVTAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(46447..46920)
                     /locus_tag="VQO19_000424"
     CDS             complement(46447..46920)
                     /locus_tag="VQO19_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET1348735.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKKYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDAIIGFVMIAYDKKIGISSGNYLLFRFMIDKNFQNQGYFKPIMDK
                     VLDYVRTASAGLGNKLWLSYEPENEHARSCYLSYGFKETGEIYENEVVAIYDFNN"
     gene            complement(46910..47509)
                     /locus_tag="VQO19_000425"
     CDS             complement(46910..47509)
                     /locus_tag="VQO19_000425"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HET1348736.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGFIRDLPETPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            47633..47815
                     /locus_tag="VQO19_000426"
     CDS             47633..47815
                     /locus_tag="VQO19_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HET1348737.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            47953..49326
                     /gene="mnmE"
                     /locus_tag="VQO19_000427"
     CDS             47953..49326
                     /gene="mnmE"
                     /locus_tag="VQO19_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HET1348738.1"
                     /translation="MITREFDTIVAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIVDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPEAIETSELPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNEGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(49373..50308)
                     /gene="dapA"
                     /locus_tag="VQO19_000428"
     CDS             complement(49373..50308)
                     /gene="dapA"
                     /locus_tag="VQO19_000428"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HET1348739.1"
                     /translation="MSYQDLKKCKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLVYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFIAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(50364..51440)
                     /locus_tag="VQO19_000429"
     CDS             complement(50364..51440)
                     /locus_tag="VQO19_000429"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HET1348740.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIASF
                     PGAVLEDDVVHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(52026..52098)
                     /locus_tag="VQO19_000430"
     tRNA            complement(52026..52098)
                     /locus_tag="VQO19_000430"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(52063..52065),aa:Thr,seq:ggt)
     gene            complement(52198..52707)
                     /locus_tag="VQO19_000431"
     CDS             complement(52198..52707)
                     /locus_tag="VQO19_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HET1348741.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(52705..52801)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            52830..53261
                     /locus_tag="VQO19_000432"
     CDS             52830..53261
                     /locus_tag="VQO19_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HET1348742.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            53343..53720
                     /gene="mscL"
                     /locus_tag="VQO19_000433"
     CDS             53343..53720
                     /gene="mscL"
                     /locus_tag="VQO19_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HET1348743.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(53762..54856)
                     /gene="hemH"
                     /locus_tag="VQO19_000434"
     CDS             complement(53762..54856)
                     /gene="hemH"
                     /locus_tag="VQO19_000434"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HET1348744.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTIRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            55011..56234
                     /gene="pepT"
                     /locus_tag="VQO19_000435"
     CDS             55011..56234
                     /gene="pepT"
                     /locus_tag="VQO19_000435"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HET1348745.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLIDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSNRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(56270..56899)
                     /locus_tag="VQO19_000436"
     CDS             complement(56270..56899)
                     /locus_tag="VQO19_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348746.1"
                     /translation="MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANSDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            56864..57085
                     /locus_tag="VQO19_000437"
     CDS             56864..57085
                     /locus_tag="VQO19_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348747.1"
                     /translation="MDLFQELICLVQKTFYFFLSICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNIL"
     gene            complement(57356..58367)
                     /locus_tag="VQO19_000438"
                     /pseudo
     CDS             complement(57356..58367)
                     /locus_tag="VQO19_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(58593..61712)
                     /gene="phtE"
                     /locus_tag="VQO19_000439"
     CDS             complement(58593..61712)
                     /gene="phtE"
                     /locus_tag="VQO19_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HET1348748.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKKLSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPGN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLPETGNSTS
                     DSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSETGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            complement(61923..>62330)
                     /locus_tag="VQO19_000440"
     CDS             complement(61923..>62330)
                     /locus_tag="VQO19_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET1348749.1"
                     /translation="KPQTEKPEEDKEHDEVSEPTHPESDEKENHAGLNPSADNLYKPS
                     TDTEETEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAMETLTGLK
                     SSLLLGTKDNNTISAEVDSLLALLKESQPAPIQ"
BASE COUNT        18377 a        13086 c        10378 g        20489 t
ORIGIN      
        1 tcatagaact actataccat attttgtttc gcaggaagtc taatctaaaa aaggtaaatt
       61 taagattggc aatacgaaca ttaaacagaa ttccatttct ctttttagaa tcaaaacgac
      121 aatattgtgg aatctctaca ggaacaatag actgcgacac taaaatatcc tcccttagtt
      181 ttactttact aatagtatat aggaggagag ccctgaatcc tagacccttt gttatgatgc
      241 gcttacaaac agagttggaa aaaatcttaa aagcagaaaa acgcatgata tcagccccta
      301 acacttgata caatgcgttt tattatgaaa agatctactg gattttttca taataaactt
      361 ccagtagtct tttcactttt tattaataag ttccttcttc accttggcta gtcaagataa
      421 caggtccatc tttcgtaatg acaaattggt gttcatactg acatgacaat ccaccgtcaa
      481 tggtcttatg cgcccaacca gttttcatat ctgtatcaat ttcccaatcg cctgtattga
      541 tcattggttc aatggttaag accattcctt cacgaagacg gagtccacga cctgcaatac
      601 catagttagg aaccattggt tcttcgtgca tagttgggcc aacaccatga ccaaccaaat
      661 cacgcactac accgtaacca cgactttcag cgtattcttg aatagccgca ccgatatcac
      721 cgatacgatt tccaacaaca gcttgctcaa tacccttgta catagcttct ttggttacat
      781 ccatcaagtt tttgacttct tcggacggtg taccaacagc ataagcccaa catgagtctg
      841 ctaaaccacc agaatagctc tgagtgtatt ttttcatttg ttcaacattg ttgaagttta
      901 attttgagac attcaggtca gatttagcaa tgggacctcc caaaaccata tcaactttga
      961 gcaaatcacc atctttcaag atataatgac gagggaaagc gtgagccact tcatcgttaa
     1021 gagagcaaca ggtagcataa ggatagtcca tcatggcacc gtcaacccca atctgaagtg
     1081 gaaggaaatt ttcttcttta caacgacggc ggacatattc ttcaacttcc cacatatcta
     1141 cgcctggctt aatcaaatca cgtaagccta tatgaatact tgctagaaaa tcaccagcct
     1201 tgtccatagc ttcgatttca cgagctgatt ttaatgttat catcttttct cctagtttct
     1261 aattaatttt aacagtcaca tttgcttttg aaacaatctg gtgaccatga taaatatcgt
     1321 aatcaattat agctgaccgt ctcgtatgat gaataatccg tgcctgaatg cgcaatatat
     1381 catctatctg aacagcctgc aaaaagtaga ttagcatctg ctcgataatg agattgcgac
     1441 cactattaac aactaaatct tgggtcatgt gggtcagaat ttctgccaat acaccattag
     1501 ccaaaactcc atttttttct agcataaagg gttccactgt aatgactact tcatcatggt
     1561 gataagagag cttttgtcca atctgctcag aaaaagttgg tagagccgaa acttgagaac
     1621 ggctcatctt ctccatgaca tctcgtcgcg tcacaacgcc aagcaaagtt tgattgcttc
     1681 gaacaactgg taccatttca aagtcttctg cgatcatccg ttgactcaca ttggcaatat
     1741 ttgtcgataa tccaaccaaa aatagactac gagacataac cttatcaatt gtcgtgcttg
     1801 gtgatttatc accagcgtct ctcatggtta caacgccaac aacgacctga tgttgattga
     1861 taacagggaa acggctgcta cgattcttac gaaccaagtc caaataatct ttaactgtat
     1921 ctgtctctct cagaaaacca tactcatgac tagggcgata aagtttctca actgtcagaa
     1981 tatcagtctt gatttggaca tttgacaagg ctttattgat catggtcgcg acggtaaagg
     2041 tatcatgctt acttcttaga acaggaatcc ctttttgatt ggccagttta agcacatcat
     2101 catgaacctg aaatccccct gtaaccagaa ctgcattttc attttccaag gctagcaact
     2161 gaatacgggt tcggtctccg acaatcaaga gccccccatc atgaaggtaa gacaagatat
     2221 tttgttcagt catggcacca attgaaaact tactaaattc tctctctaaa ccttcttgcc
     2281 cagccagaac ctcagaagaa gtcacttctg caatttcagc aaacgttaat ctctctatag
     2341 caactttctg ggatttaaca cgaattgttc cacttctagg acgggtctcc acaattccac
     2401 ggttttcagc ttctttaata gcccgatagg ctgttccatc actaactcct agatgattcg
     2461 aaatgctacg aacactgacc cttttaccta ctggtaattc ctccaaatag cttagaattt
     2521 cctgatgctt actcattgaa ctctcctttt acataccgaa attcaagata atcccgcatt
     2581 tttcttgtgt aacgatcact tcccttaaac tgacggaaca aactaaatcc agacttaaga
     2641 gcaactcttt ggctagcttc attttcaagg tgggtaatga tagataattg ttttaagcca
     2701 aattcctcaa aagaaagctg acaaattttt ctaacaacct ctgtcataaa tccttgcgac
     2761 caagcatctt ttctcaaaaa atagccaagc tcagcttctt ttttgatttc atctaacttc
     2821 tcaaatttaa tagaaccaat catttgttga tttttctggt cacaaattgc ccacactccc
     2881 aaaggggact tcataaagta attggccagt gcatattgac tttcttccag acttgcctgc
     2941 gttgggaaaa taaattgaag attttctgga tttgaagcta tctcgcggaa gtcctgacta
     3001 tcactaaaaa agaaaggacg caaatacaag cgatccgttt caaaaaaaga aaacattgct
     3061 aatttggtcc aaatattcat aaacacctct acggtttaat cctcaacaag tctaatatcc
     3121 gctcctaaat tacgtaattt ttcgataata tcagaataac cacgtaagat aaactcgata
     3181 ttggtaattt cagttttacc ttcagccata agcccagcaa tgactagtgc agccccagct
     3241 cttaagtcgg tcgctttaac actggcccca cgtaaatcac gtccacccgt gtacaaaata
     3301 tgaccatttg ttgtcgaaat atccgcatcc atctttgcta gttcaaaaac atgatttaca
     3361 cgtttttcgt aaatcgtatc gacaattgta ccacgaccat tcgctcttag taaaagaggg
     3421 gtaagcggtt gttgcaaatc agttgcaaag cctgggtaag gagctgtctt aatattgatt
     3481 gctttcaaat tagactgttc ctcgacaaaa atgctgtctt cagatacagt cattctcact
     3541 cccatttctt ccaacttagc aataaaccct tccaggtgtt cgtaaagaac attatttata
     3601 cgaattcctt taccaactgc agcagctaaa gatatatatg ttccagcttc aatgcggtct
     3661 ggaatcacct gatgacgtgt cccatgtaat ctttcaacac catcaataat gatgatatta
     3721 gttcctgccc cacggatatg ggcacccata ttattcaaga gagtagctac atcaataatc
     3781 tcaggttcac gggctgcatt ttcaataata gtacgaccat ttgctttaac cgcagcaatc
     3841 atcgtattaa tcgttgctcc cacactaacc gtatccatgt aaatacttgc accatgaagt
     3901 cctgtatctt tagcagataa cttcatgtta tctccctcgt agctagcagt ggcacccata
     3961 gcttcaaacg ccttaaggtg taagtcaatc ggacgaggac caagatcaca tcctcccggt
     4021 agaccaactg tcgcttcacc aaaacggcct aagaggctcc cataaaaata gtaagatgca
     4081 cgaagactgt taattttacc ataaggcatt ggaatatttt gaacacctct tgggtcaatc
     4141 tccaatacat cgtcataacg cttaacagta gctcccatca attccatgat ttcgacaaga
     4201 ctggctacat ccgaaatatc tggaacgcaa tccaaagtca ccacatcatc agccaagata
     4261 atagctggaa ttaaggcaac gacactattt ttagcaccac taatagtgat ttcaccttgc
     4321 agtggtaatc caccattgat aacaattttt ctcattctaa gttttcaata ctctttcaag
     4381 atttctaata aggtcttcaa aataaagtat atcataaatt tatccttttt tccatccttt
     4441 tcaattttat tggataaatc agagttgacg agttagtaac tgaattacta atactcaatg
     4501 aaaatcaaag atcaaactag gaaactaacc gcaggttgct caaaacactg ttttgaggtt
     4561 gtagatggaa ctgacgtagt cagtatccta cacatacggc aaggcgatat tgacgtgatt
     4621 tgaagagatt ttcgaagagt ataatctttc tcgaatcgct attgcccctt ttttatcccc
     4681 taaaactgag taggggctaa gactagatct cttatctaag tatcggaata cggctgttca
     4741 actaaatttt agcaagaact tctccccttc tctcaattca cagaagcgtt ttatacatac
     4801 cgtcctatca gacaatctat tttaaagata accgtgactc aggatcactt ctatctgtcg
     4861 ttttctcttt attaggttac gactaccttt ttggacttta gagtttgagg ccctcttatc
     4921 cgctatatac gccttattat cacgttcctg ttcgtagagc cacgatttct ctatcccttc
     4981 ttctgacaat tcttatttcc agcgtcagac ttaaaacggt ctatccccag accattttaa
     5041 tccgctacct cacgatagtc aggcttggga atcgctattt gactcgccga gaactttgac
     5101 atcagatata ctataacaaa ttgaaataag aatcaaacaa tttaattttg aaattcaaat
     5161 caatttataa caatatagtt gattgaaact agaatagtac acctctactt ctaaaacatt
     5221 gttagaaatc gatttgtcct gttctcattt cattttacta tattttagaa gatatgctgt
     5281 gctattccag attcagttcg ctatacatgc ccgtcgtacc acaaaatccc gtgtctgatg
     5341 aggcacggga ttttttagct tctttactga gatggatttt cctttttagt tcgtgccaat
     5401 ctcaaggcac gatttggatt gagacgatta aatagttctt ccaatttctt ttcattccaa
     5461 acgtctgcgg cggaaacaaa attaccatcc gcatctcgga aagatatcgg tttatctccc
     5521 ataccagtct cctagtctac aaattcaaac tcaaatttac caatgcggac caaatcccca
     5581 tctttagctc cacgcgcacg aagggcttca tcaaccccca taccacgaag ctgacgggca
     5641 aatttcatga cagattcatc acgatcaaag ttggtcatat taaagagttt catgagtttt
     5701 tcaccagaaa gtacccatgt cgcatcgtca tcacgactaa tttcaaaggc tttttcttct
     5761 tcgtcaaatc catagtaagc ttcttcttcc atatcggact cgtcgtagag caaaaattct
     5821 ggtgtcttgt ctaacaattc agctgtagca tctaaaagtg ttgccagacc ttgcttggtc
     5881 aatccagaaa ttgggaagat agccggtaac tcttcaaatt catcataatt ttcagacaat
     5941 tttttcttaa agtcttcaag attttcctga ctctcaggca tgtccatctt attagctaca
     6001 ataatctgtg gacgctccat gaggcgaaga ttgtaagact ccagctcttt attgatagct
     6061 aggtagtcct catatggatc acggccctcg ctagctgaca tatcaatgat gtgaaggata
     6121 acacgtgtac gctcgatgtg acggaggaac tgagttccca aaccaacacc ttgactagcc
     6181 ccttcaatca aacctggcaa gtcggctact gcaaaggatt cacctgattg ggtgcgaacc
     6241 atacctaaat ttggtacaat agtggtaaag tggtaggcac caattttagg cttagctgag
     6301 gtaataacac ttaaaagtgt tgacttccct acagatggga atcctactaa accgacatct
     6361 gccaagattt ttagttccaa ttgtaactca cgttcctgac ctggttctcc attttcagag
     6421 atttccggtg caggattttt tggtgtcgcg aaacgaatat ttccacgtcc accacgacca
     6481 ccgtgggcaa cgataaattc ttgcccatgt tcaatcaaat ctgttaaaac cttgccagtc
     6541 tccgcatcac gaacagtcgt accttgtggt actcgaactc taaggtcctc agcaccacga
     6601 ccatgcatcc ctttggtcat ccctttttca ccagaatcag ccttgaaatg acgactgtag
     6661 cggaaatcca tcaaggtacg tagtccttcg tctacaacga agaccacatt gcctccacga
     6721 ccaccatcac caccccaagg gcctccatta gggacatatt tttcacgacg aaaggcaacc
     6781 ataccatcgc caccattacc agccttgacc ttaatcttag ctgtatctaa aaacatactc
     6841 attatttctt ctcactttaa aaaagggctg ggaaatccca gtcactaaat tttcttgaat
     6901 ctattttata gattactgag ggcaccaatt gcagttgcaa aaattcccaa taaacttgct
     6961 actagcatga taatcacgat aaacaaggtt attttctcaa acatagtttt tttacgattt
     7021 ccattatctc caaatgccat ttttctctcc ttcgttacat tctattttct attatcttag
     7081 catgaattga gctagttttc aatagtcagt tgctactggt gcgataatcc ataaaataat
     7141 gtaagctaca attccagctc cgtaacagca agtaagaaca ccccaaatga cttgaacgat
     7201 agtcggatcc atatccagat aatgggccac cccagcacaa acacccgcaa tctttttatc
     7261 acgaccgctt ctcattaatt gtttttttca tagctgttcc tctttctatt cttcatggtc
     7321 tttccaatag tctctcatac tgatcaactg tgtttttgaa gccttcaaca tgcgtctaga
     7381 tccttttaca ggtacagcaa ccacctgttg ctgaagatac aaaactgtct taaagatacg
     7441 ctgactgacc gtatcatctt tagccaaatc tttctggaag ttatttgaaa taatggcatc
     7501 cagataaaac tcatgcactc gtttcccaaa gttctcagct gaaatctcat acaatttctc
     7561 tgataaggta tgctcgttca tgtctggtgt tgcaatcagg gcttccaaaa tagcaccagc
     7621 caaatcatgt tctccatagt acaaggttcc aaacatttta tcactgatga ggttgttcaa
     7681 ataaggattt ccgtgagcaa tgacaggtgt tccactggct aagctttcca agtaggtcaa
     7741 accttgcgtt tcgcttgtcg atgccgaaat gaagaaatcc gccgctttat agtaaagagc
     7801 cgtctcacta ggagcaatca tccctgtaaa gatgactgag tcttgaatct ctaggttctg
     7861 ggcttgctct ttgaggtcat tcagataagg gccatcccca gctactacca gtttaacctt
     7921 gtcttcctct ttcagaacat cagcaaaggc tgctaaaact gcttgaatat ttttttcata
     7981 ggagattctc gaaagactaa gcaacgtctt ttcaccatct tgaatcccta gtttactacg
     8041 cagttctttc aaattttcct gcttgatttc cggacgctca aacttggcta attcaatccc
     8101 agtaggaatg atccgttttt caaccttgac cttataatca gatagcaagt cacggacaat
     8161 ctcactaggg caaataaccc catccacatc atgcaggaaa cctctaacca gatacttgac
     8221 catactcggc cggatcaaca tccccttagc aatataatgg acatagtctt catactgggt
     8281 gtgataggta tggatgactg gaattttcaa ttcacgcgca atccaaatcc ccaacaggcc
     8341 aagagaaaat tctgtctgag tatggataat atctagctga tactgtttag caatttcaag
     8401 tgccttgcta aaacctcggt aggcaaagcg acgatcctta aaagcaaaga aaggaacact
     8461 tggaatgcgg ataatttgcc aatcttcgta gcgattgaca tccttatctg tcgtcgtaaa
     8521 gataaaaaca gcatgtccct gcttttcaag ttctgttttc aaggttcgaa tactggtcgc
     8581 aacaccagaa acctgaggaa aataggtatc tgtaaataaa ccaattcgca tagattacct
     8641 cactttttac tttctcccta aagcggcttg tttctcataa aagtccaacc agatttgtaa
     8701 cagatgctct tcagaatact ctctggaaat attcttagcc ttttctttga gatcttttaa
     8761 gacagcagga tttgcttgat attccaaaat agcctctttc atctcttctc tacccgctgt
     8821 cgcccgataa tttccctcca aaatcacctt atagagatct aaatcacgca acataatagg
     8881 agcctcacaa ctcgcagctt ctaaaatagt cataggaaag agctcattgt aactaggcaa
     8941 caagaaaaga tccgctagag catacaattc gcgcatccgc tctggcgata caatgcctgg
     9001 aaaaatcaaa tttttagggg gattttccat aattttctta tagtgttcat aaccatctgt
     9061 cataccacca aaagagaagc caccagccca gataaaggta atctgaggca attcctcagc
     9121 cagacggata aagtcatcaa tccctttacg tttctgaact tgcccagcac ctactacgat
     9181 aaactgattg tcactaagac caagatctgt gcgcagtctg actacctctt cttgtggtag
     9241 aggatgccat ttttccttgt tgacaaagtt aggaatatag gtcacttttt cacgtggaat
     9301 accagctgct accaaatcct caataaacat aggattgacc acaaccaagt gctccatccg
     9361 gttgtaaaaa gaaaatacat agcgtttcac aattcccttt aagaaaaatg gaattttcaa
     9421 acttccttca agtgtagctg gcaagaaatg cacatagcca atctttctcc ctgagcgttt
     9481 cttttggaag gttgataaat aatagggaaa atcaatcgta tgaaagtgag tcacatctgc
     9541 ctcgattgga agattttctg taacaatcaa ttggtccttg gcagcacggt gaagaagacg
     9601 aactaattca cggtaagcac ctgaaactcc ctgtcctgct actttctcac ttgaactcaa
     9661 catattgatg cgtaatttct ttttctccat aactactatt atatcatttt ctttgaataa
     9721 aatcagcaaa agaaaggaga gactagagga aaagagggga aatttcctcg cttttccaac
     9781 agtctctcac atgcttttat atgtttactt aatgcctagg gcaatgcggg catagcgact
     9841 cattttttca actgtccagg ctggatacca gactaattta acctcagtat ccgttacttc
     9901 tggaacctct atcatagcat cataaatctg gtctgtcaaa aggtctgcta agggacaacc
     9961 catagttgtc aaagtcatgt caatctctgt ttgccctgtg tcaccgtcaa aacgaatctc
    10021 atagatcaaa ccaagattga caatatcgat tcccaactca gggtcgatga cttcttccaa
    10081 ggctgttaaa atccgtgttt tgatgttttc aatttgctct tctgtataag ccatattttc
    10141 ctcactctta gtcttcaata aaatcacgaa gcggtttgct gcggcttggt tggcgtagtt
    10201 ttctcaaagc ctttgcttca atctgacgga tacgctcacg agttacgtta aagactttcc
    10261 ccacatcttc aagtgtgcgc atttttccat catctagtcc aaaacgtaga cgcagaacat
    10321 tttcttcacg gtctgtaaga gtatctaaga tttcatccaa ttgctcacgc aagacgatac
    10381 gagtcgtata atccactgga ttttcaatca cttcatcttc gataaagtct ccaaggtggc
    10441 tatcgtcctc ttcaccgata ggagtttcaa gagatactgg ttcttgggca atcttcaaga
    10501 tttcacgaac cttatcaggt gtcatatcca ttcgttcagc aatctgttct ggtgtcggat
    10561 cttgccccaa ttcttgaagg agattccgct gttcacgaac caatttattg atagtttcaa
    10621 ccatgtgaac tgggatacgg atggtacgag cttgatccgc aatagcacga gtgatagcct
    10681 gacgaatcca ccaagttgca taagttgaaa acttgaaccc tttagaatag tcaaacttgt
    10741 caaccgcctt catcaaaccc atatttcctt cttgaatcaa gtcaaggaac tgcatgccac
    10801 gaccgacata gcgtttggca atagaaacaa ccaaacgaag attggcttcc gcaagacgtt
    10861 gtttggcttc gatatcgcca gcttcaacag ccagtgccaa ctctttctcc tcttcattgg
    10921 tcaagagagg aacgacccct atttctttca agtacatacg gacagggtca ttgaccttag
    10981 cagaagttga cccaatcaag tcctcatcgc tgagttctgg ttcttcttca ttgctaagaa
    11041 cacgcgcact tggatttcct tcgttatctg tgatagaaat gcctgcatcc tgaatccgtt
    11101 gcaagagatc ttcaatccca tcagcgtcca aggtaaaagg aataaccaga cttgcattga
    11161 tttcatcatc tgttgctgtc cctttttgct tatgattacg gataaattct gctacctgta
    11221 cgtcaaatgt tgttacttct ttttgttttg ttgccattat tactccattc ttctcttttg
    11281 ggaaattaaa cgttcaaatt cttctagggc tgtatctgta tctcctacat ggctagcttc
    11341 ctgcaccttc tttttgattc tcatattgtc ctgattcaag agagccttgt ttcgagtcat
    11401 ctctacttca ctaagttcct gcggcgatat ctcagcaggc aaatcctgag ctaaaacttg
    11461 gtaccaagct ctttcaactt cctctgtctg ctctgctaaa acttctggag gaagatttcc
    11521 atactggcca agcaagtcat ataagacctg aaattcaggt gtagcaaatg caaagtcttc
    11581 tcgcaaacgg taatcgttca aaacaagagg ggattccatc atccgataga gtagatgggc
    11641 ttctgccctc ataatagccg ataactgctt ggtgataggc atggtgattg gcgtcggtct
    11701 ggaaattcct tccatgcgat tctgcctttg cacctgacga ctctcattaa caatctgctc
    11761 aatctgggca taatcaaagg acgccagact gtcagctaaa atatgaatat agctgttttg
    11821 agcagcgatg gacttttctt gaacaatcaa gggagctatt ttttcaataa actcaatctg
    11881 agcctgcaga ttttcactgt tttcaggttt gtactgatga atgtagaact caatcggact
    11941 aatacgagtt ttcgttaata gataggccaa gtcttctgga ccattttttt gtagatactc
    12001 atcaggatcc aagttatcag gcatgctaac gatttgcaca ggcatatcac caatttcatc
    12061 caatgctttc aatatcgcgg cttgcccagc cttatctcca tcgtaaacaa gaaccaattt
    12121 cttggttaac cttttcagat gctcaacatg ctctcgactc aaggccgttc ccatcgacgc
    12181 cacagcattt tcgattccag cctgataggc tgcaataaca tccatgaatc cttccatcag
    12241 gtaaatctca ctagtttttc cagaagattt ttttgcccta tccatatgat ataattcgta
    12301 acttttgtta aaaattgcag tcgatcggct gtttttatac ttagaagttt gtgaatctgt
    12361 tttttgccag atacgacctg agaaggcaat gacctttcct tggtcatttg tcaggggaaa
    12421 cataatgcga ttgtgaaagg tgtctacaaa ttgattggca tccgagagat aaaacaggcc
    12481 tgaatccagt aaatcttctt cacgatactg atcagacaaa cgttgataga gatagtttcg
    12541 ttctggaggt gctaaaccaa tccaaaaatg tttaagcact tcatctgtca aaccccgctg
    12601 ataaaggtaa tttctggcct cttcgcccat agtcgttgtc atgagaatag catggtaaaa
    12661 tttagccgca tcttcgtgca tatcataaag agcttggtga ggcgaggctg gcttctgttc
    12721 actataaagc ggtttttcaa cctcaatccc gacacgctga cctaagattt ggacagcctc
    12781 cataaaggta accccttggt actcctcgat gaatttaaag acatcacctg agcgaccaca
    12841 accaaaacag tggtaaaact gcttgtcctc tacaacgttg aaagaaggtg ttttttcacc
    12901 atgaaaagga cagagcccta gatagttccg tcctgccttt tgtaaagaaa tcacatctcc
    12961 tatgacttcc acaatgttgg cattgttttt gatttcttca atgacttgtt tgtcaaccat
    13021 acacaatacc tccatgttat catagtttac tttatatagt atactttatt tcagaaaaaa
    13081 agtaaaccat ttcactcatt ttccctactt tattcaaaga gttgataata atcagagatt
    13141 ttcatttttg cttttttctt cttggtttaa atcttggata atccgtcctt ctttcatgac
    13201 aatcaagcga ttgccgtatt tgagagcatc ttccatatga tgagtaatca taagggctgt
    13261 tagctgatct ttcttaacaa attcatctgt caattccatc aaagcaacac tagtctttgg
    13321 atccagggca gcagtatgct catctaacag gagtaattca ggtcgcttca aggttgccat
    13381 caagagactc aaagcctgtc tttgtccacc tgataagaac tcaatcggtg tattcaagtg
    13441 tttctcaaga ccatttccta ctttttcaat ggttgcctga aattcatcct tatagctagt
    13501 caagcgtctt ggtaacaatc cacgcttttc accacgaaac ttggcgatta aaagattttc
    13561 agcgaccgtc atacggggag ctgtccccat ctttggatct tggaagacac gagacaggta
    13621 cttggcacgc ttctcgggtg aaaacttagt gagatcttca cctaaaatac ggatagttcc
    13681 actagttagt gataaggtcc ctgctatagt gttaaagaga gttgattttc cagcaccatt
    13741 tccgcccaaa atcgtgataa agtcccgttc aaaaatttct aaggaaacat catttaaaat
    13801 aatcttttct tcatcaaagc catttttaac gattttggtt gcatttttta attctacaat
    13861 tgctgtcatt tgcttaactt ggctcctttc aagattgttt gcttaaatgt tggaatcatg
    13921 aggcagactg ctaaaatcaa ggcactgtat aaacgaaggt aacttgtatt aaagccaagt
    13981 gcgataactg cccacactaa aaattgataa gcgatagaac ctacaacgat agtaaccaaa
    14041 cgctctgcca agctcaaact cttgaaaata acttctccaa taatcaaact tgcaagcccc
    14101 acaacgataa ccccgatccc tcgagacaca tcggcatagc cttcttgctg agcaatgagg
    14161 gcacctgcaa gggcaatcac accatttgat aagaccaagc ccatgagctc catgcgtcca
    14221 gtatgaatcc cgaaacttct agccatatca ggattatccc ctgtagcaat ataggcttgt
    14281 ccgagtttag tgtccaagaa aaagagcatg agagcaataa caatactcac aaagatgaga
    14341 cctgtcaaga gttgattcaa atccgaatca aaaggcaaaa catcctgaat ttgcttggtt
    14401 ccaagcaggc ctaaattcgc acgtcccata atcaagagca tgattgagtg acaagaagtc
    14461 atcaccaaaa tccctgagag caaggttggg atcttccctt ttgtataaag aaggcctgct
    14521 gccattccag ccaaacaacc tgctcctaca gcaacaagtg tcgctaaaaa tgggttcacg
    14581 cctttggtta tcaaagtgac agcaacagct cccccaagag ggaaggaacc ttctgtcgtc
    14641 atatctggaa agtttaaaat cctaaatgtc ataaagattc ccagacctag aatagcccag
    14701 acaaatcctt gagaaataat ggaaacaatc atattttatt taatcctttc tatattcatc
    14761 tttttaaaaa atgggaagag tctcctcctc cctaccttat ttattcgatg acttgtcctg
    14821 cttctttgag aacagactca ggaatagtaa tacctagttc ttgtgctatt tttttattga
    14881 tgactgactt accagttgaa aagacattga ctggggtatc ggctggtttt gcacctttca
    14941 agacttgcac aatcatttta cctgttgcca caccaaggtc atgttggtca attacaactg
    15001 atgccaaacc acctacttct accatagctg tcgcactggg ataaattggt ttcttagaac
    15061 tttgattgct agagacaacc gttggaaatc ctgatgcaat ggtgttatca attggaaccc
    15121 aaatagcatc taccttgcta gtcataacag tgacagttga ggcaatttca tttgttgaag
    15181 gaactgcaaa tgtttccact gtcagacctg ctttttcagc ataagcctta aattcttcga
    15241 cctgtgtttt tgaattgtct tcgctacttg agtaaagagc tccgattgtt ttcacattcg
    15301 gtgtcagagc cttgatgagt tcaacttgtt gttgagctgg attgtggtca gatacccctg
    15361 taacgttgcc acctggtttt ttcaaatctt taaccaagtt agcaccaatt gggtctgtaa
    15421 tagcggccat gataaccggt aagtcttttg ttgcactagc caacccttgg gctgctggtg
    15481 ttgcgatacc aaccacaagg tcattcccat ttgcaaccaa ttgtttactc attgtcgcaa
    15541 ccttactttg gtcaccttct gagttcataa aatcaatttt aacttgatca tctttatatc
    15601 cttcttctgc aagtccatct tggatccctt tataaatcaa atcaagggat ggatggctca
    15661 caaattgaag cacaccaatc ttggttattt tcttctcatc cttattattc tgagcttctg
    15721 atttattcat tgaagaataa atcaagcttc ctgctactaa gactgctaat gcagcaataa
    15781 ttccaattaa acgtttattt ttcattctgt ttctcctttt tatttccttt aacatatttc
    15841 acttatctaa acaagcgacg ccatcgtttt ctttccatac taacctccat caaaaaaatc
    15901 ctcacacaaa aaacttgtgt gaggacgtcg atgcgcggta ccacctcaat tatagggaat
    15961 ttccctatcg ctcagtctcg caataacgag atgcactgta aggtgtgctt accgaatttt
    16021 tataatttca aattctaaat agcattcagc ccaattttca tcatcgccac ttatctgttt
    16081 tcagctacca cagactctct aaaaagtttg tatgattact tttctgaatg gttaaattat
    16141 atcattttta aattacttgt caatagtcta ttagaatttt tttgatattc acttttagta
    16201 ttcactcttg aaaattatca acctgaatta cgcaatcctg tcgcaattcc gttgatggtg
    16261 atatgaatca atcgttcttg atcactggac aattctccac gacgttggcg tttaatcaac
    16321 tctaactgaa tatagttgag aatattaaag taaggcatac ggtaatccag actagctttt
    16381 agatatggat tgtcagctaa gagttcgtca tgtccttcaa tagccaagat aacgttctta
    16441 gtaacttgcc attcatttaa aatagtctca tagatggcct taacttgctc gtcttcacaa
    16501 agtttagcat attcaaaagc aatattcata tttgattttg acaaaaccat atcaacattt
    16561 gaaagaagcg attggaagaa aggccaattt tggtacatat ctcgtaagat agcaatattc
    16621 tctggatttt tattgataaa ttccttgaag cttgaaccaa ccccgtacca tccagggaac
    16681 ataacacgac tctgtgacca tgagaatacc caagggatgg cacgcaaacc accgatttca
    16741 gtaatagtct tacgagcggc tggacgagaa ccaatattaa aacttgaaat agccttgatt
    16801 ggacttgact cgaagaaata atcatagaaa tgctcattac caaagaccaa atcacggtag
    16861 atatcgtaac tacggtccac tacttgatcc ataatggctt cataacgatt tggggtattg
    16921 gtatcgctct tcttctgagt aatcatacgg ttaatagctg ccgatactag catttcaagg
    16981 ttatagtaag cggcgtcttt gttaccgtat ttattcccaa ttacttcacc ctgctccgtc
    17041 aagcggatac gatccttgat agacttgagc ggttgagatg taatggcttc ataggttggc
    17101 ccaccaccac gaccgacagt accaccacga ccatggaaga aggtaacctt aacgccaaat
    17161 tcatctccaa tagcagtcaa ttgttgttga gccttgtaga gggtccaaca tgatgacaag
    17221 taaccgccat ctttattact gtcagagtag ccaagcatga tttcttggta gttatttcgt
    17281 gagtcaatcc attttttggc aaggctaaga gaaagatatt ttctcattgt ttcctctgaa
    17341 tgatccaagt cttcaattgt ttcaaaaagg ggaacaatct gaacacgcgc cctttccgta
    17401 tccaccagtc ctacttcttt taacagaata gctaattcta gcatatcaga aaggctggtt
    17461 gcatgtgaaa tgatggtctg acggatgaca tcatctccca acttatcttt caaaacacga
    17521 gccgtcttaa aaatagctaa ttcttttgct aataattctg atttttctgc gtgagtcgca
    17581 gaaagaattc ggggatcttc ttctaattct ttcaagagaa ggtcacactt ttcttcttcg
    17641 ctcaactcgc tataacgaga atgaattcct gctgatttca agagttctgc cacacaggct
    17701 tcatagacgc tagagtcttg tcgcatatca attgatgcta agtaaaaacc aaatatctct
    17761 actgcctgca ataattccac aaaatcacct gaaatcaagg actcgccctt attttctagt
    17821 agagaatctc gaatggcaat caaatccttg tagaaatcat tggcggtttc ataacgagtc
    17881 ccaacttctt catcctcaat cagataggtt ttagttgcct gaatttttga ttgaatatca
    17941 aacaaggcac gacggtaaag ctctttttcg cggtaaatcg agttatcctt ggattgacga
    18001 gccatttctc tgacttgctt gctgacgttg acaatgctag ttgaaagaga aaattcacga
    18061 taaagttggt aaatcttttt atcatagtag ttcatgatga cttcacactg agtgagtgca
    18121 gactgcttca aggtctttgc tgtaacaaat ggatttccat cacggtcacc acctatccac
    18181 atacccatgg tgattggttt agcctgtttt aaattcagac catgcgcttg cgctaagcgc
    18241 ttatactccg tcgtcaaatg aggtacagct ttcaaaaagg agctgttata atattccata
    18301 gcattcgtga tttcgttagt cacttttaat tttttctcac gaatcatgtc tgtctgcatg
    18361 ataatttcga tgtaacgacg caaatcattg taccatttat ctttattgat caaccccaac
    18421 ttaacatcac ggtatttacg caaaagacta tgaatatgat ttgttaaatc caacatactt
    18481 ttgcgttgca cttgtgttgg atgggctgtc aaaacaggga caacattcaa gtgttctagg
    18541 atctcaacgg cattttcctt ttctgctacc aatttaatcg ttgtagataa tttacctaaa
    18601 tagtcctgat caatattatt ttgatgattg atttcataag ctaaatccac atcctctgaa
    18661 atattaatca aaagaggtaa gatagagaaa tagcgtgaaa tatagaccat ttcatcattt
    18721 gataagctag tcactagacg gtttagacct tgataatctt cctgcgttga taattctttc
    18781 aactgtatta ttttttcaaa ggtctctggg gcaagcatat ttttagtaat atcttccagt
    18841 aattctgtta gaatcaagac ttcttcttgc acaacacttt tattactata attttctaat
    18901 ttttgaagag acataaacta tcctttcttt atcctacttc aacagaaggt tcattggttg
    18961 attttccaat tctcggtaca acttagcgcg tttttcactg gcatcaatat ttaagacaaa
    19021 ggctactgcc actgataaga ctagaagact atttccaccc tgggataaga aagggaaagt
    19081 cactcctgta gatggaatca agcccgaaat ccctccgata ttgacaaata cctgaaccaa
    19141 catcatccct ccgacaccga gtgcaaccat ggcattgaaa ggattctccg ctcggatacc
    19201 gaccaagata atccgcaaaa tcatgaaaaa caagagagct aaaataagac tggcaccaac
    19261 aaagccaaat tcttcaatca cgatagaaaa gacaaagtct gtatgagctt ctggcaaata
    19321 acctcgtttt tcaatcgagt ttccaagacc tagaccaaac caaccaccat tgaccatggc
    19381 aaaataagaa ttagctaact ggtgacctgc atcagcacga tcggcaaaag gattaaaaaa
    19441 ggcactaaag cgcttggcta catagccaaa tactggaatt tttgaaaagg tctcaacacc
    19501 gattaggctg atagtggtca agacaaagac agaagtggca gatacgagcg ccagaatggt
    19561 tgaaaaccag cgataagcga ttccactaac tgtatacata atcaaggaaa ccaagactaa
    19621 aatagtcgca tttcctaaat cagggaaaat tcccaaactt ccaatcagaa ctaggagaac
    19681 gaatcgccaa tcattaaaag cacggggaag ccattgattt tgagtcaaaa cttgaaaatc
    19741 ataagtagct atttcttctt gctgtttgga gaatcggtga gctaaatacc aaataataat
    19801 gatttttaag tactcagctg gctgaatagt tactcctgca accgaaatcc aaccgtatgc
    19861 cccgtttact gaaataccaa taaaacgagc caagaacaat aaaagcattt ctattaatat
    19921 aactaaaatg attagtcgct catttctcaa aaaatctagt ctcaatttat aaattaaggc
    19981 aatcagtatc aaactaacaa tccaaaagat tccttggttt cgaaccaact gcaaggcgct
    20041 cttgccttct tcaattaaaa tagcactggt ggtcgaatag accacaatca agcccaaaat
    20101 agataaaagc aagtagggaa tcaagatgga ataatttaat aagtgcctct tactaatctt
    20161 catagtatca ccactctact aggatacaga caaatctgtt ccaaattccg ttttattttc
    20221 tagttttgat tgctattata ccattttttc agaaagaaaa aaactcttac cttacaatcc
    20281 ttcgaatttt actgttttta cagaattaag gcagaatttg aaatcgtaaa accattttga
    20341 ataagagttg cttcaaccca ttgactccga cggattaagt tgctttcgtg aatgccaaaa
    20401 tcagccgcaa tttgttcata agtgctctat tctcgcatgt attgaatagt taccataagg
    20461 agatcgtcta ggcttaattt gctttttcgt ccaccttttg cgcgtttacg ttgataagct
    20521 gtttttaaca cagctaacat ctcttcaaaa gtcgtgcgct gaacacctac aaggatcttg
    20581 aaacggctat cgcttaattg tttacttgct tcatcatcca tagttttatt gtattgtatt
    20641 tttgtttcgc aggaagtcta ttattccttt cgttccaagg tttttacgct tttagcaaca
    20701 agcttacaca ctgagcgttt cggacttacc atatcatttc gttggagatt ttatcatcaa
    20761 tttttagatt aaaaaaattt cccaatcttc acaaacttct gtagcaggaa ttgtatgaat
    20821 ctttctaagt atctttcctg cttctacacc atatgtgtat tgttggtttt ctgaataagc
    20881 taaaatgcta tctattgcat ctcttccgtc tatccattcg tgtaaagaat gtacttcgtc
    20941 atcgcagagt tcaatgctaa ttggtttaca catcggaact ccaagagaag ctactttctc
    21001 catcatatca aattcaaatt tttttataat ctaacttcga cttatcagaa acacgcaaga
    21061 aatattttta ctgattttga tctgtcacac aatatttttt atcatctgac cagcccttat
    21121 ttatggctat cttactacta aaatccatca agcacactcc gattcacttt acaacacttt
    21181 ttgcagtttt cactagtaac ctatccagtt cgtctacact tttatttcct agatccattt
    21241 ttacattatg aaagttagtc aattttctct atgatgtttc caagtttatc caatacaaga
    21301 caagaatgat catttagtgg aattatggga acattaacga gttcttcagc tctatcctta
    21361 tttgctttat cattccagga atcataatgg acactaatta aaaactgact aaagagtcct
    21421 aatccatttt ttatctttat ctgatgatct gaattatcat taggtgagac atagactttt
    21481 tctcctaata gtagggctcc tgcagaaaat cctataattt ttgcctcttt attaagcata
    21541 tgatcgatat aacttttgaa ctcctgatta acataagtta gcaatatatt tttccgtatt
    21601 tccaccaccg atgataatta tgtcagcatc tagatagcta tcaagatcaa tctgctcagt
    21661 gtccaggagc aagtaatcaa tgtttagatt aggaaattga ctttgaaaaa cttccgtgta
    21721 ctttttcatg tacggttccc aattttctcg aaaaactgta aaaatgataa ttcttttaat
    21781 cttggttgat aatacaattt tatcaacaat actatatttc ttcattgggg gattcccacc
    21841 catcaaaaaa atttgttctt tcaagttaac acactttcta aagatacata aagtttaaac
    21901 aagtttattc acgtttctaa attataattt tttcttaaaa tgaataattc tatttgcctc
    21961 ctgaaatcca atattgagat gaaatcttat agaatccgta ttcgttaaag tacagtcact
    22021 tgcaaattcc ttacatcctt tatttttcgc ccattcctca cattttgtac agagattttt
    22081 agcaatatcc tttaaacgat attcctcgtc aacaataatc ccttctaaga atccaacagg
    22141 actatattta caaccttcaa cataatcaaa tctgagtgaa catagtgcta gacctacaat
    22201 tgtgtcacct tcaacttcag taaagattgc agtatttttg ccattcgtat atttttttac
    22261 ttcatcaata gcttctttat cggtcaattg gggccataat tgtttcatta gtttagccgt
    22321 ttttataaaa tcttttgtta ttccatccat attgatgttc ctccgcaaat tacaagtaaa
    22381 tgtttcgaat catgctgata ctttgttact cattgattga taccaatttt atactgcttt
    22441 caaaaggctc atatgtttta tacttaatta cttcgtcttt aaaattaaat aaaggtgtat
    22501 ccggcttagc attccataaa ataatcaacc acattataac attataaagc tgctttgcag
    22561 tttcattcca cttttcaggt tgtaaatttc cactccctgt attgtcatat tcttgtctat
    22621 tatttacatg agaatcacct acaagcggat taaaaagagg tagccctttg tgattaatta
    22681 gttctaaaaa atcccttgcc gcacccatgc aacactgaat aacttccttc ttgccatcaa
    22741 ttttactctc agcgataaat acataatatt catcttcaat agttgctcct gcatcactat
    22801 gtttttgttg atttgctaac agcttaatat gtgctttagg ctaaacttca aaatctctaa
    22861 caattctttg tcttgtttca tgtcctctac aattcattta agttctcctt tacaagttta
    22921 gtaactagcc ttattatact atataagata tgaaatgtac cataatcttc atcaactagt
    22981 ttttagaaaa tcacaaatcc atctggagag atgacaagct gattctccaa ttcttggcaa
    23041 ttgcttgcta gtgctactgc ttctttctct aaaagataat cttctgttga ttggttgaat
    23101 attgctttga ggatccgtcc ttcgtatttc cattccagag ctactagatc agatttgatt
    23161 tcttgaaggc tatacttgcc atgcgaaatg attactgacg cgtatttccg aatcttaatc
    23221 agcctcttca taaagttcag catatcattg tcacttgata cacgttccca aggcatacaa
    23281 cgacgacaat ctggatctgg tcctccagtc aaggctagct cggttccgta ataaatgcac
    23341 ggtgttcctt tttgtaaaaa gagaaaggct aaggctgatt taaccagttg aacatcttca
    23401 ttggccgtcc acaggattcg ctctgtatca tgtgaatcca agagattaaa catgacctct
    23461 gaaatctgct gcttgtaata catagactct ccattgattt catcgatgaa ctggtctgtc
    23521 ttcttaattc ctcgtaagaa atagtccttg atactatcag ataaaggata attcatgacg
    23581 gcatggaact catctccatt tagccaaggc tgagatgtat gccagacttc tcctaggata
    23641 taaagatcag gatttttagc taaaactgcc ttacgaaaat ccttccagaa ctgatggtca
    23701 atctcattag ccacatccaa acgccaagca tcgatattaa actcttcaat ccaataagtc
    23761 gcaaccttta aaagataatt cttgacctct ggattggctg tatttagctt aggcatatag
    23821 tcctcgaaac caaaaacatg atagggtaag tctctcttat taactagctt ttcagttgtc
    23881 actgggaatt gttgaatatg gaaccaatcc ttataagcag actgttcacc atttttgacg
    23941 acatttttcc attgaagaga ttgcgaacca atatgattaa ataccgcatc cagcatgact
    24001 ttcatgccac gatgatgcgc ttgatccacc agttcccgaa aggtctcctt gtctccaaaa
    24061 tgacggtcaa tttcaaagta atctgtcgta ttgtacttgt gattgcttgt agattcaaag
    24121 atgggacaaa gatatagtcc agtaataccc aagtcttgca agtaatccat atgatcaata
    24181 atcccctgta aatcaccacc aaagaaatca tcgctcttag gtgtgacaga tgaatcccag
    24241 tctaaagtcc cttctgggtt taatagagca ttgccattgg caaatctttc aggaaatatc
    24301 tgataccata ccgtatttga aacccagtca ggaaccttgc aggcatcaat ctcatgaaga
    24361 taaggcaact taaatccatt cccaattgca tgaagatttt ctagagaatt ttccacacac
    24421 cctttatcgc catacaaaat attttgacct tctgtatctc tgagctcaaa aagatactgg
    24481 atacgtgcaa agtcaactga cacttcaacc tgccaatggt caaataaggt accagaagtt
    24541 atcttgacca tttcttttgt atcctgataa aactcctcca taaagataaa agggtcccca
    24601 tagtgcaagt tgatgctttc aatgtcccct ttcttagttc gaattcgaat atggagtttc
    24661 ttatccttat aaagataggc atactccgac tcagtcctat ggtaaatagc actcaattcc
    24721 atcaatttat ctcctaaagt attcattcaa attttacgca aacgttttca aactcaatga
    24781 atccagtata ctatttttgt gaactatttg caaggaatgt ccgttgttaa aggaactatc
    24841 ttttaaagta tacaaaaagc cttaaaaaag gctttctcta tatactaatc ctctttcggt
    24901 tttgaaaata cttctacttt cggttttgaa aatacttcta ctcgctgagc taggactttg
    24961 atttctacag gtaggttatc tgatttatct ccgtcaacat ctgactccaa ttcactatct
    25021 gaagagattt taatattacg cgctttgata tactcgatat tatcatttgc gataacatcc
    25081 ccttttaata aatcaggaat gacggataat ttggagaata tagaggcatc tttcagaatc
    25141 aaaatgttgg catagccgtc cttgttttct tcaaagattt tcttatcagc gaagtaattt
    25201 gtcaaaagga ccaaaacatg gctagcttca ccaacataat ttccattttc tgtctcaacc
    25261 ttaatgttaa agacctgatc tgtcatgaca gacttcatag tatttacagc ataggctaaa
    25321 ataccttgtt ttgttttgtc ctctatttca acattgtgaa tcgcctcagg cagagaaccg
    25381 atactaaaga tataaccaaa atagttgtca tttgctttac cgatatcaat cttattggtt
    25441 aaatcaaaat ccagttcgtc aattgcgcca tcgatgtctt gattgatttc caaaagtttt
    25501 gtaatgaggt tacccgtacc gcctgggata atccctaact taggaatgta gtctctctca
    25561 tcaatacctg aaatgacttc attgacagtc ccatctccac caaacacaac cactgcatca
    25621 tactgctcac gagaagcttc ttcagcaaaa tgtgttgcat ccagcgcttt ttcggtaatt
    25681 ttggtttcaa catattcaaa gtattctttt gctttattct ccagcttttc tttgtaatcc
    25741 aaagccttct cgccaccaga agtagggttg ataattacca ttgctttttt cattgatttt
    25801 atccttaatt ttaaatagaa atgtttacat ttcgtcgtat gcaagtaaat gtaatcctat
    25861 tatacaatga aaatacagaa aagagaaatc tgacgtactg gagattaata cacttttatt
    25921 ctattttccc atcgcctaac tacatccttt aagggttcat ccaagtaaga ataggcctta
    25981 tccttgatcc aatcaggaat accgtaagct gcctctgcta tgctacaagt gattgctgcg
    26041 agagtatcac tgtcgccacc aagtgagatg gcatttctta tcgcatcttc gaagtctcta
    26101 ctttcaagaa aggcgataat ggcttgaggg acagtttcct gacatgtttc gttaaaacga
    26161 tagttaggac ggatttcatc taaagtttga gatagattgt aatcgtattc tttttctata
    26221 taatccttaa ttcgtctttt acactctata ggattgtcgt taattgatta ctcgtactct
    26281 ctacaataac caccaaatta aaaacgacat agaaagatag catcagctgt agccatagcg
    26341 cctttgacac cttctggatg attatgagtt acctctgcag aaagactcgt aagtcctcta
    26401 gatgatggcc atataccagt tttcgcataa aaaccacagt ccatgatcca agcacatgga
    26461 gaaatacgca tagctgatcc attcccaaag ctattataag gctcacggtt atcgctgttt
    26521 agccatgcat taaaccgagc accgtaatca gcattcggat acattctgcc atatttcttc
    26581 atcgcgtcaa tgaagtcgtc tttttgtcca ccattcataa ttgcttctgc aacagcacag
    26641 gtcataaccg tgtcatctgt aaaaaagcag tccttccgaa ataaaggaaa gtcctttgtt
    26701 ttgatattgt tccattcgta aacagaaccg acaatatctc caataattgc tccaagcatc
    26761 agattcctcc ttgttcattt tgatgctttt tatattggtt atataccata tttattttag
    26821 aaaacaacat cctgttggat tttaaaaatt tcattttttt caaaataggg ttttaccatt
    26881 tctttccacc tagctctatg aaaattgatt gattttaaag gagataggcc ataatttccc
    26941 aatgcataac catcatttac ttcaacaaca agtgttctgc catcgcgagt aacaccgata
    27001 tctagtccat aagctattgg cgcatctttc caacatgata tcgcttcatc aattacactt
    27061 gcatcaaatt gtgcatgata atcacctgta tagggtcgaa catctaatac gcgaccatct
    27121 aacacaaaac aacgccattc agctatgaat tctacaacct cactaatcca tataggatag
    27181 tcgaaaggta gaccaatacc tattaaatca tgggttccat taacaactct tccagtaaag
    27241 acttttgaac cagctttagg cttaataaat tttccccaat tatcaggtat attcacaatc
    27301 tctcctaaaa taccagcata aatctttcga ccataaaact ctttaagctc aataggatag
    27361 tcatgaaccg gaacgtttaa gcccatcatt tttagtaatg ctctagtctc cattatataa
    27421 tctacaacta tatcttcact tgttaactct tttatttcag aaaaagattg atataaaaca
    27481 gcttcttctc cttgtaagta ggcacctact tgagcattgt atttattaat tgaaacctca
    27541 cttggtaatt tactttgtct aatataaaca accatttcat cactcctata tcactagtgt
    27601 tacaccaatt tgtaaaaaat aatagcaatt ttgctcttat ttttttgagt aaatagcccc
    27661 cataatatca tcgaaataat caacggtatt taggagtaat tcaataacct gggactttgt
    27721 tagtcgcatt ccccttctat ctctagcatc ttctactaaa ttttcaagtt tctctagatt
    27781 tttatcatcc aagctaatca ttattctatt tttatcggtt gccattttca tcacctcaag
    27841 ttaattctat cacaggtgta acacttgtgt caactggctt ttataataca ttagtttaaa
    27901 agtggagagg atttttaaca cagtaacttt aaatctttgg tattaaaaaa ttttcacaat
    27961 atttatagaa ataaaatctg tctcaaatca gttatcaaat ctagtataaa ttatgagcgg
    28021 ctactctaat actttccctc taaacaagaa aaagacttac actcaagggt tttcttcccc
    28081 cccttcgtta taacgttttg actcttttac tagcaaaggt atatactcac aaggaacttt
    28141 ggttgactat tgaatctctc caacttcttc tttaacatat ccttctacat cttcaatctc
    28201 tacaaacatt gggtctaagt gacacaagaa atgccaaact tcgatccctt tttttctgta
    28261 aagaatcgct tcaccgtctt cacttccgaa aaagcttctg tcgatttcat atccgcggct
    28321 ttctaagaag tcttttgctt tacgatagtt cgtttctctt gtttcgacat aggctttaac
    28381 ttcatggttg ttaacgacat atgcatcaat ttttgaatat ccttcgatca ctctatcatt
    28441 tttgagggat aaatttgaaa tctctttcca aataatgttt acattttcct caggatcgaa
    28501 cataaattta gataaaggaa caatatttcc gttaaaaata atttccatat aatccggtat
    28561 gtttttagga ttaaaatact ccacttcaaa accatcttct gtttccagag tgtatcccgg
    28621 gatttgagcc acaaaggctt tcccatcttc tatggaatca aatgctacta aatctttaga
    28681 ataatcattt tggtacaatt ccaatataac catcgataat ctctccattt tcattatcag
    28741 gctaatgtaa ataagcacgt cacctgacca attcaggctc tctgtatcat ctcatcatat
    28801 ttcctactta ctttacgagt cctataccca gaacacacct tatcgacctt cggtctcacc
    28861 tcgtcgcatt ggctgaacat ctacttttac ttcgctgatg cttcaactcg tacaagcagt
    28921 gataccgcct cagcgtgatg cgtcagtggg actcaaaaag tttggggaac cttttgagga
    28981 ttaactacgt ttctctaata aacttacaca ttcaacttgt tcatcattgt ccaaatctat
    29041 gttgagattt tcttctataa ttggtagctt aaaagtaatg gattttagcc attgtccgtt
    29101 agattgtttt tcttcataaa cttgaatttc agaaatcaaa gctgaaatta actgcctacg
    29161 ctctacatca ttcatgactt tatagagctt atcaaaatag atcagaacct tatatatgtt
    29221 atctcctgta agtttttcag cttcaatagt ctgtttcttt gctttcgcat caattagtga
    29281 tgattctaat tcatctattt tgtcatacat acgatatagt ctatcatcta aatcctgttt
    29341 ccttctctta tagtgcttat cttcaacatc taaattatct atttcctcaa ttagcttaaa
    29401 ctttgtagaa tgactctttc tcaattcctt ttggtaatta tctatttctt tttctatttc
    29461 agaggtatcc accttcatgt tgattttttc ttgcatcata gaagcaaatt tcggattact
    29521 tactatcttg acaatcacct ctgcaacagc atcatctaac aattcttctc taatttgctt
    29581 actgaatgta cacttatgac ctcttatcat ctgcctatgt ttacaaccat agtaataaaa
    29641 atctttatac tttgtgccat ctttcttttt cttgatacac ttgttcccaa acattcccac
    29701 tccacatatc gggcatttta caattccaga aagcaagtgt gtgcgtgtat cttttccttt
    29761 attcacatgc tcatatttct ttgcttgaga ttttagctta acctgagcag cttgccaaac
    29821 ttcatcggaa actatagctt catgtatccc ttcagatatt agatattcat cttgttcaac
    29881 ctgcttatat tcatttcttg taccatgaac tttttctaaa gttcttcttc caaatgctat
    29941 tttcccatta tatacaggat tctttaatat ctttcttata agacctgcat caaacaaagg
    30001 attcttacca ttctgtcttg ggatttttct aattccatga ttctctaagt atttagatat
    30061 cccattggct cctatcgtag tatttacata ctggtcgaaa atcgttctta ttgcaactgc
    30121 ctcttcctca tttataaaca gcttgccgtc ttcaagttta tatccatacg gagcaaagcc
    30181 accattccat tttccttccc ttgctttttg aatgcaatct tccattgttt gaatacggat
    30241 gttttctctt tctatttcag ccacagctga taaaacagaa atcattagtt tcccagcatc
    30301 tttagatgaa tcaatgccat cttcaacgca gataagatta actccataat cctgcattat
    30361 ctgaagtgta gaaagaacat cagcggcatt tcttgcaaat cttgataact taaacacaag
    30421 aacaaaagat actccatctt ttccagattt tatatcttcc atcattcgat tgaactgtat
    30481 tctaccttca atagacttgc cagacttccc ggcatcttca tactctccaa caatttcata
    30541 atcgttgtaa atagcaaaag ctttcattcg tgatttttgt gcctctaacg aatacccctc
    30601 tatctgtatt gacgtagata ctcgtgtata gaggtatact tttatttttt cttttgacat
    30661 agtattaacc tcaatataat ttttctatat catatataat ttttttaatt taagtttgga
    30721 ctatcatttc aagtatatta taacactttt attagtccgt ctcaatttgt gtttttgcca
    30781 tgtcaaaact atttttcatc tcttgatttt ttgctggcgt tggatcgggt agattatcta
    30841 aatctaaagc accagcatat tttgcaatca gatttgctat taaatcagcc aatccattcc
    30901 agtcattgtc caatatatac ctcctctaaa gttttatatc taataattat ttgtttaatt
    30961 aagttttttg acattgacaa gtgctttgga ttagcaacat aggaatctca cctccgcctc
    31021 tattccggat gagccggctt caaccttaga agtatcatta tcctcatttt cttcatagcg
    31081 gatagggtat ccctccctat attcaaactc ttacttatcg ctcactttct ttttacttag
    31141 cagaactttt tttgccgaat tattcagccg aaagatcttg acggataggt tattacgctc
    31201 caaaaataat taacgtcttg tcttggtcta ttcaattgtt aaggttcaaa atttatcgag
    31261 aattattaat ctttttaaaa tttgaccatc agaaaatatt tatcttaatg taacaaaatt
    31321 ctataaatta ccctcttata cttaacagtg aaaagaagtc tttcttggta accaattttg
    31381 aaatagaatt tgcttatata aaaaggtcca attcccactg cataagtagc agtgaaaatt
    31441 agaccctctt ggtaactgtc atctaaaagt cttctagcat ttctttaatt ttctaatcac
    31501 ctttaaagtg tcatatttat atttttttat ctctggcata ctttgatacc tttttagact
    31561 taaagtcttt aatagtgcct ttccacctct ttttatctat aaagattctc ctacatcata
    31621 attcattttt ttatttaaac ctttctgtct tagtttgtct ttatcttctt cataccattt
    31681 taagattgtc acatagtggt tttgataggt cttaccactg ctttccatgt atctggatag
    31741 tttatttatc attatatctg tgtgtgagtt taatttttct tttagatttt tatattcttc
    31801 tttgcttaac cttacatttt tgaattctcc ataaaaaaat gggggtggac tttttatcta
    31861 tctctccctc tctctttatc tatctctata tctttccatg taattccaat ctggagtacc
    31921 tctactgtct atcggtaatt taattttgat atctggcaat actgtgctag atatttgatc
    31981 tttatattca gtatttttta aagcttgcct aataattgaa gttaaataga atgctacttc
    32041 tttattcaat tctttatttt ttaattttaa acaatgaatt ttcatatcta ggcttgcttt
    32101 atatttatga taaaagactg ctcctaaaaa tgaaacagat ataaaatttt caaaaactct
    32161 ataattttta tcatctatat cttcgtagta acctaagata ccattgtcaa tatttgtagc
    32221 actaattcta ggagtttttc catcgagtaa atatcttttt ggaatagatg agcctgttgg
    32281 tacttgactc gatttcccct ttttttcggt aataaatatt tctttttatt ttgttgtctg
    32341 atatttttcc tacctgtcct ttgtaggatg agtattttct agattttctt gaataacttt
    32401 ttacttgaag ttttagcttt tgaactagtc gttgtacttt ctttttgttt attatcagtc
    32461 ctgatctttt taatattgct gttattctct atatcctatt tttcattcat gatattcttt
    32521 tactaatttt atcttaaatt ctgtgctgta tttgccatta aaaaactgac ctcctttagt
    32581 tagttttttg gcctaacttt tgagggtcag ttcaaaattt gcgactttta aatgaattcc
    32641 aatattcaat tattaagagt taacatggtg cttgccaata ggaatcatta gaggcgaatt
    32701 ggaaataggg tcacgtataa tttttgcttc aagattaaag atatctttaa ctagtttatc
    32761 atttagtata tcttcaggct ttccctctgc aacaagttta ccttctttaa ttgcaaatag
    32821 gtaatcagcg tatcttgctg ttagatttat atcgtgcaaa atcatgcaaa tggttgtctt
    32881 atatttttgg tttagatcag tcaagaggtc taatagttct atttgatatg agatatccaa
    32941 gtaagtagtt ggctcatcta aaagtaggat acttgtatct tgggctaggg ctagagctat
    33001 ccatactctt tgcctttgac ccccagaaag ttcttcaact aggttatttg ctagatcttc
    33061 aacattggcc ttaaccattg atctgtttat tatttcaagg tcatcttttc caagactctt
    33121 aaaaggcttt ctgtagggga aacgaccacg gcttacaaga tcagctactg ttattgattc
    33181 agggattatt ggagattgag gtaatatagc tatgtgtttt actaaatctt tttctttata
    33241 agaattaatt gatttattat caagcaatac ttctccctct aatggcttta taagtcgaga
    33301 caaggtttta atgagtgttg atttcccaca accatttgac ccaataataa ctgatatttt
    33361 ttcttcaggt atttttatat ttatattttc caagattatt ttttcatcat aaccgcaggt
    33421 aagattattt gaccacagac ctttcattat atattcctcc tgttcatttt tattagtaaa
    33481 tatattaagt atggtgaacc taacaagcca gttacaacac ctactggata tctagctggt
    33541 aaaatatttt gagagaatat gtctgataac aaaactagta aaactccaac caatccagct
    33601 aatattgggc ttcttttctt gccaatattt aaggctatgg gaccagctaa aaaagatata
    33661 caagctattg gtcctgtaat tgaagtagaa aaagcagtta aagatacagc gcaaaaaatt
    33721 aaaacaagcc ttgaaagctc gggatttgca ccaagtccga ttgctatttc ttcaccaagt
    33781 tcaataattt ctagtctttt attaaaaaat aaaactaata tagtagcaat aatacttact
    33841 attagaacaa gaggtatgtc atctaacttt gtaaaagata aagagccact gagccatctc
    33901 ataacttctt gtaattcata tcttgctact ttcaacaata aaaatgaggt gcctgctctt
    33961 gtgacagctt gaaaaccaat acctaatatt atcagtcttg ctgctgaaaa accatctttt
    34021 ttagctagta aaaataatat taaagatgat gttagtccac aagttattga aataattcca
    34081 gtagttaaac tatttgtttt taataccaat atgcaaaaga ccgctgcaat agatgaagaa
    34141 cttgtgacac cgattatatc aggacttgca agaggatttc ttaacatagt ttgaaagata
    34201 aatcctgcca atccaaaaga ccagccagct ataattcctg ctaataattt tggtaatcta
    34261 atttccataa tcgaaaaact agctccagga acagtttcac tatttaagac tttaatcaaa
    34321 gttgaaaaag aataactttc atctccgata agtaaaatga aaaatgatag actgattatt
    34381 attaataaaa atagtgagga gaatagtgtt attctatttt ttcttttttg aatacctata
    34441 attaaatttt gcattagtta ttaacccctc tatttttcat agttacataa ataagtactg
    34501 gacccccgat tattgcagta attatcccta cttcaatttc acctggttta cctaacatac
    34561 ggccgattat atcacatata agcaagagct ctgcacctat aaaagatgaa gaaatggtca
    34621 ttgtgcgtat atctttgctt ataaataagc cacaaaagtg aggaactata agacctacga
    34681 agccaatagg tccaccaatt gcagtaatac ttgaacataa aagcacactt gcaattattg
    34741 caagtgatct tatcctatta acattaactc caagaccaac agccatttca tcacccatag
    34801 ctaaagcgtt taaatctgat gaaataaata tagctatcaa gtgacctaaa attataaaag
    34861 gtagtagtgt agatatagaa gataatgtag ctgctccaag gctacctatt tgccaaaatc
    34921 taaatttgtc taagacgtta ttattcggta aaattaaaaa acttacaaaa ctgcttaaag
    34981 ccatactaac acaagttcct gataaggcaa gttttatagg ggtaaggcct gcttttccgc
    35041 ttacagcaat cgcgtataca aaaattgcac ttactaagcc accaatgatt gcaaaactta
    35101 tatggcttat gcttgatgaa attcctaaaa aagaaagacc aattactaca ctaagacttg
    35161 ctcctgtgtt tataccgagt atacctggat cagctattgg gtttctagta actgattgca
    35221 tcaatacacc gcttatggca agactagaac ctgctaaaat tgcaaaaata gttctaggta
    35281 ttcttttata tataattgat ttaataaaat catcatttgt attacccatt ccaaaagctg
    35341 ctaaaaaatc tctgatatta atttcttttg ttccaagctt taatgacaaa aatattgtaa
    35401 taagaagacc taggcagatt acaaaaatta tgcctaggtt tatttgtttt ttatttcgca
    35461 tttttgcatg catttcctaa aagatttaga tattcttcaa tagtatagtt tattgaaagt
    35521 ggtgttggag tgcatgaggc tgctaacggt gtattatctg gaattacagc aacggcacca
    35581 tttttaattg catttatttt acctaaaaga ggatcttttt gtaaagcttc aagagtttta
    35641 tcatcaccat aagttatgat tacatcagca tcatttatct tatttgcttc ttctgcagaa
    35701 atttcctttg caaaactatc ttcactctca aattctttta atgattcagg gaaaactaga
    35761 cctaaatctg ttaaataatt tgctcttgga tctttgctag tataaatcca gaattttgat
    35821 gtatctgcag cattaatcat agtaaataat actttttttc ctttgatttt tcctttgatt
    35881 tctggatgtt tttctaattc tttggatata cgagcttcag tatttttgat taactcatca
    35941 ccttcttttt ccatacctaa ggcttttgaa tcaattctaa tcatatctct ccataaagtt
    36001 tgccaaggtt tagatttgta tgctgctaca ggagcaattt ttgatagagt gtcataatct
    36061 tctttagtta taccagaata acctgctaag ataacatctg gtttagaatt tgatattgct
    36121 tcaaagttaa gtccatccaa atcgtcaaat aggttagctt taccatttag ttctttgatt
    36181 ttttcttctg tccatggtaa aactccttta tcagcactta caccgtaatt tgcttttgaa
    36241 agtccaacag gaactattcc taaagctaat gctacatcat gatttcccca agcaatagtt
    36301 gcaactcttt caggtttttt atctaatata gtttgaccga aagcatgatc taaaactatt
    36361 ttatcaggcg catgctcttt agaagtattt tcttcatttt taacagaatt agaagaacaa
    36421 gcgctaaaaa ctatacacat agctaaaata gctattagaa aaaatttgtt tttcataaaa
    36481 actccttgaa catatttcaa gtctattata tcgataataa ttatcattgt caatagatgc
    36541 agttacaaat ttaataatat aattttttca aaaaaggatc tagtttttat ttttagttaa
    36601 attatgtcta tatttttcat taactcatca ataaaaattt gtttgctaat atctctttct
    36661 tctgattttg tttcaaggat tattgctaca tcattcatat ttttaggtaa ataccaacca
    36721 tctggcttat ctgaatatcc cttgaagcct aattgattaa aagtagttat ttgaccagta
    36781 ccttgattga tgttttcttc aacttcatta aagcctaata cttctcttgc ataatcccta
    36841 acttgatctt ctgtccttaa agtcattttc tattcctcgt cactaaaatt atcttcaaaa
    36901 ctaataatat cattaggagt gcaagataaa gccttacata ttctttctaa attcttaaat
    36961 gtaattggtt tatcctttcc catttgtgcc ataacatttg ttgtaagtcc tgccatagct
    37021 attacatctg ttttctttag tccttttttt gctaactgta tccataatgg tttatagtta
    37081 agtgccataa tatccctctt tttttcttca ttagatttat ttaattatag cataaatatt
    37141 gattttattc aatcttacat tgatttagtg atttgtttta gagaatttgt tgtgttattc
    37201 cgtccttatt ttgccataaa ttgttttaag tgggacctct tatccttacc atttttacct
    37261 cctaattttg agtataaaaa agacgacaga gtttttaatt tctatcgtct gagatttaca
    37321 tattaaattt tcatcacaaa ataagactct ttaaagaatc tttaaattca ttggtatgct
    37381 aattacaata tccattatta aaatggatac tataaacagc acaccaacta tttatttttt
    37441 gagttttaaa ctttggtaga agtcttgaac tccttatatt tacataacta tttgcctcta
    37501 taactattat gacacgaaac caacaagcaa gttcaagcac ctccttatct ttattcaaat
    37561 gaggactaag atattcacaa actttatcat aaacctcttt atcttttttc ataaaagggg
    37621 catacaactt agcaaattta tcctaaaatt ttttgttgcc tttatcaatc atttcaacac
    37681 tcctttaaat ataaaaatga tcctatcaat ctttatattg agcctatttt ctaattgata
    37741 ccttgcaaga aaggaataat agctgttcct ataccaagta ggaatgtaat aaatgcagaa
    37801 agtcatatac tgtcattctt ttctattaaa tcattttgaa gtgtctcaaa gcatccatga
    37861 tggcttcttc tttttcaggt gtacactgtg gaataatttg tttatccttt ttagacttgt
    37921 tgtaatgttc tcgtaattct attccacatt tcttttttat ctgtgcaata tataatgtcg
    37981 aaacttttaa ttcaaattta ttccaaacat attctttgat ttgagcatat gttgctttgc
    38041 tctccgcact tgtcaaattc atctcatcca gctcaatttc aacacttatg tgcttatcga
    38101 catcgagttt ggacaaaagt gctaccgtct cgacgtgatg cgtttgagga aatagatcca
    38161 ccggctggac tttcttcaat tcatatccca attcttggta gagtttgata tcacgcgcca
    38221 tggttgctac attgcaggag atataggcga tgcgatcggc tcctgtttgg gcgcttgctt
    38281 tgataaagct ttctgtcaag cccttgcgtg gaggatcaac caagataacg gttggttgaa
    38341 tcccatcttt aagccaattc ttcatagcat tttcagctgt gtcacagaca tagtgggcgt
    38401 ttgaaatatt gttcagctga gcattttttt tactattctc aaccgcttct ggaatcagtt
    38461 caacaccgta gacttctttg acatgcttgg cgactgataa accaatagtt ccaataccag
    38521 aataggcatc aataatcaca tcatcttttt ttaactctgc aaagtcaatg gctgtttgat
    38581 agagtttctc cgccatttca gtattgactt ggtaaaaggc tgggccagcg atttggaagt
    38641 catttcccaa catctggtcc gtaatatagt cttgaccata aagagtgcgc cactccttac
    38701 caaaaatcgc attggtattc tggtcgttga tattttgcat gacagacaca atctctggga
    38761 actgcttgat aacttgttca atcaattggt caacacgaaa aacttttgga cgagttgtca
    38821 ccaaaacgac catgatttgt tctgaatagt gaccacgacg caccacaaga ttccgaatca
    38881 atccagactg ttccttttcg tcataaggtt ttaaatcaaa acgacggagc aggtctcgaa
    38941 gagctactac gacttggtca atgacaggat cctggataaa gaaatcttca aggggcatga
    39001 ggttgtgcga attcttacgg aaaaatcctg tttccaagac accattcact cgacgaacgg
    39061 gcacctgcgc cttattgcga tacttgactg gatgttccat accaagcgtt tcagcaactt
    39121 ctacatctgc aattccagca atcttgtaga gactgttctt gacttgcttg gttttaaact
    39181 tgagctgttc tggataagaa aggtgtccta aatccgcgat tcctgaacgc aggtaagcca
    39241 aatctagatc ttgattacgg tgtggtgact ggacaaggta tttttcaact tttccaaagc
    39301 caatcttttt attgaccttg aggacacgca tgagaatttt ttcactcggt aaagcattct
    39361 ctacaaaaaa gaccaaacca tctaccttgg caactcctgc cccttcatgg gtcaaatcaa
    39421 caatttcaac ttctacaata tcatttttct ttaacattct tttctctttc tattggccga
    39481 caaaaaagac ggcaacgtta cggttaccat ccattatacc atgaaatttc ttaagaacca
    39541 aaactcttga agaagttgac aagggcttgc cagagggagc ttaagaagtt accaccgtcc
    39601 tctagcgcct tatccgcatc aaagttaagg ttgatatttt taaaactgtc gccagcttgt
    39661 gatacgatgc tttgtttaag gtcatttagg gttttagtga aatctgcatt gctgaggata
    39721 tcactctttg agagattcaa ggcaaaattg atgatgatat tgatctggtt tcctgttatg
    39781 acctgatcaa gtttgtaatt ttttaaggta tcttcaacaa tcttgcggat atcttcttct
    39841 gtcagatttc ccttgctttc tttagctttg gcgagtcctg acttgatatc agctagggca
    39901 acgtttaatt tattagcatc atagcctgat ttgtccttgt tttcagcatt gatatctgac
    39961 aaagctttta gctcttcttg agccaaatct ttattggctt gcggcacctt ggctccatta
    40021 gcttctagcg aatagtagat cccagccaaa gcactctcac ctgtaactgg aatgggtgct
    40081 gctacagtga ttttggcgtg ttccacaccc aaagttacgg ctgcatttcg gtacatatcc
    40141 tgagttacct tagtgatgtt ttcaggtgtt tcaatcttga cctcaagtgg cgatttgtca
    40201 cctagctttt gaatcttggc tgatgaatac aactgtaagc tagagtcatt ggccacattc
    40261 atgattttag aataaacatc aggtgtcatg gtcttgagtt ctttggtatc tgttgaggca
    40321 ttgtagccca gttttttaag agtttgattt ttttggtctt cagataggga ggaacctagg
    40381 acatattcag gttggacata ggtttcatcg ataacttttt gaacatctgt tgctgcatgg
    40441 acgctattca tagctgttac tgcccacaag accgcagcac tagtcagaaa gagtttcttt
    40501 ctcataggga atttcctcct ttacttcttt agagtaatat atctatctta aagaaaactt
    40561 ataacaaaaa cacctggtct agccagatgt tgaaaagaga gtgaaacatt tgatgatgta
    40621 aaggttaagt cgtacctgtc tagaataata atagtttcct ccatttacat agagttcagc
    40681 accgtgaaaa atggaaatgg gatgaatata actataagtc tttccagtcg tattaccaag
    40741 caagggggca acagtctcac gagagtactg tttggctaga gccaaggtat tttccttgcc
    40801 attttgggcg ataaaatcga tataggcagg tccaaaatta taggcttgaa cagctgtcca
    40861 gatatctaca cccttcttct gcgccagata gagattgcct gtcagagttt gaatgccttg
    40921 ccgaatgcta gaggcattat cattgatggt gttggtggaa ccacttgcag actcactaga
    40981 ctgcataaca tcgccttctt ttccttttgt ttcagtataa atcatagcaa gcacaagctc
    41041 ttcgtttgct ggggtgtctt gttcactcaa gatttctcgc accatgggtt gataggtcat
    41101 gacttgtttg acatcttgat gaacgcggta agctttatag ccagcaaaaa ggaagactgc
    41161 tagtacaagc actcttcgaa ttcgtttaaa cattatttac tttggatatc ctcgatattt
    41221 ttgattaaga tagagtaggt tccattttcg ttttggataa actcaacaga ctcggcgtct
    41281 tgatagacgt tattgggaac gatgagctca attccatttg ataaggagag tttttggttt
    41341 tcaaatttct ttaattggcg actgacatca atttcatcaa attgaacagg ttctggtacg
    41401 gcttctttga cttggtcaat aaagctcaaa cgagccgtca gattgttgtc aaaaaggtca
    41461 ttagccaatt tctcaggtga caattcattg ctttcttcta ggttgttgaa aatagctgat
    41521 ttgaccttgg attgaaattg aaaatcatct gtgttaaaag attcagcaat tctctgggct
    41581 gttttttcca gttccttgat agatttttta ggagaaatct taggagcgac agcaagaaga
    41641 ttatctgaaa aatagttcaa aaaagtcccg ttgtacttga ttcgtttttc aatcaggtga
    41701 tacttgctac tctgaagatt gaccaccaag gcctcatcag ctcctgttcc aaatccaggc
    41761 aggttattct gagttagctt gattggatta tcaacttctc ctccgaggtg ggtcaaggtc
    41821 tcccgcaggg caattcgcaa gaaagcgaaa tgttctacac cttctttaga aaattgaaca
    41881 aaaatcaagt cattggtctt gagattttca gaaatgctaa actcctcttt ccagagatta
    41941 gccagcgtta ctgatgtctc caacaaatcg tctgtaatat gattgaagaa gggattttct
    42001 tcttcgaaaa tcccagtctt ggcttcatct gaatacacat gttcaatttt tttacgtagg
    42061 tattcttcga tttttggagt aatattgaga aacttatctg ctaagaacag ctcggtatca
    42121 tccggactga actggtgaat aatggctttc ttaatataaa tgtccataaa agttttattc
    42181 ctcgtataat gggaaggcat ctgtcaattc tttgactgca cttctcactt cttctaatac
    42241 agcctcattt tctgaattct taagggtttt aatgatgagt tcagccactt tgcgactttc
    42301 ttcttcacca aatccacgtg cagtaatagc tgctgctccg atacgaatcc cacttgtctt
    42361 gaatggtgac aaggtttcgt aagggattga atttttattt agggtaatat tgacttcatc
    42421 cagcaagttt tgagcaactt ttccgttttc tacaacctta gtcacatcaa caaggaagag
    42481 atggttttca gttccacctg aaataatacg gaaatcaggg tcttgcaaga agacatctgc
    42541 catagccttg ctgttcttaa ttacattggc agcatattcc ttgaaggctg gatccaaaac
    42601 ttctttgaag gaaactgcct tagccgccac aacatgctct aaaggaccgc cctgaatacc
    42661 tgggaaaata gctgaattaa tttttttagc aagttcttcg tcattggtca aaatcaaacc
    42721 accacgaggt ccacgaaggg ttttgtgggt cgttgttgtt gtgatatgag cgtatggaac
    42781 tgggcttgga tgaaggccag ccgcaaccaa accagcgata tgggccatgt ccaccatgag
    42841 cttcgcaccg acagcatctg cgatttcacg gaattttgaa aaatcgataa tttgagaata
    42901 tgctgaagca ccagctacaa tcagttttgg ttttacttct tgggcttgtt tcaagatagc
    42961 atcaaagtct aagagttccg tttcaggatc aacactataa gaaacaaagt tgtaggtttg
    43021 accagggaag ctaacaggag ccccatgagt caaatgacca cctgatgcca aatccattcc
    43081 cataaccgta tcacctggct caatcaagga tatgtaagcc gcacagttgg cctgacttcc
    43141 tgaatgtggt tggacattgg caaatttagc accgaaaatt tcttttgcgc gttcaatagc
    43201 aagagtctct acaacgtcta ctacatcagt tccaccataa taacggcgtc ctgggtaacc
    43261 ctcggcatat ttatttgtca agatagaccc ttgagctgcc ataacagcct tggaaactac
    43321 gttttccgaa gcaattaact cgatattatt ttgttggcgt tcttcttctt tggcaatagc
    43381 attccagaga tcagcatcat atgctttaaa atcatctttg tcaaaaatca taggtcttct
    43441 cctttattgt gtgactagtc cattagtttg attttacaat aagaaaatca aactaaaaga
    43501 tgcgaataaa ccgtttctgc attttatcac aagtatagcc aactttttca taaaatgcat
    43561 gagcacccag acgatgattg gcagaattta agcggataaa cccataacca catcttttgg
    43621 cttcttgttc caacccttgt agtaaacttt taccgatacc ttgaccttgc gcttgaggtg
    43681 aaactgctaa agctaagata ttaaatcctg ctttggaata gagtgattcg taaacttcag
    43741 cgtggacata tccaagtaag acatgattag ctgcatcctc atagccaagt aggaaatgat
    43801 gggaatcctg agacagtcta gctagttggc tagccgtttc ctctggacta aaagtataac
    43861 ccaaagcctc ttggttgatg tcacatatcg ctttcacatc tgtttcttgc aaatctctta
    43921 gcatttcaag cctcctcaaa agaaatctct ggcaaccgag caagaatatc ttctcgttta
    43981 attgcgcctt ggcgtaagat tttcaccttg tctccagaca aatccacaat agttgaatcc
    44041 tgtccagtta gaaaagcatc gtcttccaga cccagaacct cttggtcaaa atcctttaga
    44101 atttgatcaa aggttacacc acttgcctga cctgagatat tggcagacgg cccaatcaag
    44161 ggacctgtct ctcgaattaa atccagtgtg atagggtgac tgggcatccg aaatccaata
    44221 gttgcaaggt cagaatttac ccaataggga actcggtcat tggcttcgag aataatggtc
    44281 aagggacctg gcaaaaaggt ctctacaagt ttttgtagat aagctggctg attcttagaa
    44341 aagtgcaaga tatcctctaa agaggcaaca ttgagattga gcgccttgtc tctaggacga
    44401 cgtttgagct ggtaaacatg gtcaactgct ttttcgtcta aggccttggc aaaaagacca
    44461 taaaccgtct ctgtaggcag aatgacagct ccaccatttt ccaactcttg tctaatcctg
    44521 tccatcatca accacgacca tcctatcttg accaaattgg tccttgaatg ttcgaacttt
    44581 tttttcagga agatgttttc taaaaagttc gggaacactt tgaccttgct tgtatccaat
    44641 ttcaaggtaa atcttaccac catctttgag atagtctttt gcatcttccg caattctacg
    44701 gtaaatagct aggccatcct cgtctgcaaa gagagctaga tgaggctccg aatacaagac
    44761 attcaagcct acctctgact catcttcacg agagatatag ggtggattgg aaacaattat
    44821 atcatatttt tcagaaattt ctgtaaaaca gtcagatttt ttaaaaaata tttgaagatt
    44881 ttgattttta gcattttcgc tagctaaatc taaagcctct tgagaaacat ctgctgctgt
    44941 cactgaccaa tctggtctat tttttgctag agcgagagca atagctccac tacctgttcc
    45001 aatatccaga actgaaagat tcgtctcaag attttcagtt agaataagct ccactaactc
    45061 ctctgtttct ggacgaggaa tcaaaacccg ttcatccacc tttaaatgca ttccataaaa
    45121 atctgcctgt ccaatgatgt actgagctgg cttgtgagct gctagttgct ggtaaatatc
    45181 ttctacaaat tgtttttctt cctctgttgt cacctcctgc tggagggcaa aaataaagtc
    45241 tgtaaaagat agatttttca gactacgata gacaaaagag aggctttccg cttcctctcc
    45301 ttgtcttatc aactcttctt caaaatttga aaataattga gctaatttca ttatttgttt
    45361 aattcttcta gtttttgtgt ttggtcataa agcaccaagg catccacaac ttcgtccaat
    45421 ttaccagaca aaatcgtatc tagtttttgg agggtcaagc cgatacggtg gtctgtgaca
    45481 cggttttgtg ggaagttata agttcggatc cgttctgaac ggtcaccagt accgattgtc
    45541 gacttacgct cagcgtcttg ttcatcctga gcaatctgag caaagtggtc agcgacgcgt
    45601 gcacggataa tcttcatagc cttctcgcgg ttcttctgct gggtacgttc ttcctgcatc
    45661 tcaaccttga tattggttgg caagtgaacg atacgaacgg cagtcgcaac cttattgacg
    45721 ttctgtccac cagcaccaga ggcgtgatag atgtcgacac gaaggtcttt tggatcaatg
    45781 tcgtattcaa cctcttcaac ttctggcata acaagaactg tcgctgtcga agtatgaaca
    45841 cggccttggc tttctgtcac aggaacacgt tgcacacggt gggcacctga ttcatactta
    45901 agcttagagt atacagactg acctgaaacc atagcaacca cttctttaaa accaccgaca
    45961 ccattcatag aggcttccat gacttcaaag cgccaacctt gggcttccgc atacttttgg
    46021 tacatagtta gcaaatctcc agcgaaaagt gccgcttcgt ctccaccagc tgctccacgg
    46081 atttcaagga tgatattctt gtcatcgttt ggatcctttg gaaggagcaa gatttttagt
    46141 ttttcttcgt attcttcttt ttcagccttg gcatctttga gctcttgctt ggccatttct
    46201 tccaagtccg catctccgcc tgattcctta atcatctctt cagcatcgac gatattttga
    46261 aggacttgtt tgtactcacg gtaggctgta accgtgtcac gagttgaagc ctcttctttt
    46321 gaaagctcca taaaacgctt ggtgtctgaa acgacatccg ggtcactgag caattctcct
    46381 aattcttcat aacggtcttc tacagcttgt agttgatcat aaatgttcat tttttctcct
    46441 tatttctcaa ttgttaaaat cgtatatcgc tactacttcg ttctcgtata tttccccagt
    46501 ttctttaaat ccataactga ggtaacaaga tcttgcatgt tcattttctg gttcataaga
    46561 caaccaaagt ttattgccta aacctgctga cgctgtccga acatagtcta gtactttatc
    46621 cataattggt ttaaaatatc cttgattttg aaaattctta tcaatcataa aacgaaatag
    46681 taaataattt ccactactta ttccgatctt tttatcataa gctatcatca caaaacctat
    46741 aattgcatca ttatcataaa ctgccaatgg agctacaaaa tctccatttt tagtgtagac
    46801 atatgcttca gctaaactaa ttgcgttggt tgcaatgaat tgtttttgat atttcttgac
    46861 atccaaattc aaaacatcaa aataattttc cattgtaaca tctcttagtt caattgtcat
    46921 agttttgctc cttgttagag gttatcattg gcgcaaaata atgtttacgg caaaccgaga
    46981 tataggtttc attaccgcca atctggatct gttctccatc gtaaacgggc agtccatcct
    47041 gtgttcgcaa aaccatagtt gcctttttct tacaatactg acaaatggtc ttgatttcat
    47101 caatcttatc tgctaaaagc aagagatact tggaaccttc gaacagttca ttgcgaaaat
    47161 catttttcaa accaaaagcc atgacgggta tatctaactc gtccacaaca cgagctagat
    47221 cgtaaacatg atgacgtttg agaaactggg cttcatcgac caacacacag taaggtgttt
    47281 ctggtaaatc acggataaat ccaaagatat ccgtcgtctc ctcaatcgca agagcagggc
    47341 gtttcatacc gattcgactc gacacatagc caacaccgtc acgcgtatcc agagccgagg
    47401 tcataatcac aacacctttt ccttgctcct catagttata ggccaccttg agaatctcaa
    47461 tcgtcttacc tgagttcatg gtcccataac gataatacaa ctgtgccatg tttcttgctt
    47521 cacgtccgtt tctaaatttt tgctacattc tagtatatca taattttctg aagctttaaa
    47581 cggcaaaatg tggtaaaata gaagaaatca aaaactagtg gaggaagcta ttatgccatt
    47641 tgtacgcatc gatttatttg aaggacgcac gctcgagcaa aagaaggctc ttgctaagga
    47701 agtaacggaa gctgttgtcc gtaacactgg agcccctcaa tctgctgtcc atgtcatcat
    47761 caacgacatg ccagaaggaa cttacttccc tcaaggtgaa atgcgcacca aataagctag
    47821 cttaagcaga attgcttagg ctttttcaat ctccaagtag cattcattga agaaatagtt
    47881 caaatttgtt acaatttgaa aagagacttg gagaattttc caagaaaaga gctattgatt
    47941 aaaggaaata ttatgattac acgtgaattt gataccatcg ttgctatctc tactccacta
    48001 ggtgaagggg ctattggtat tgtccgcctg agcggaacag acagttttgc tattgcgcaa
    48061 aagattttta aaggaaaaga cttgaacaag gttgctagcc acactctcaa ctacggtcac
    48121 atcgttgatc ctctgactgg taaagtcatg gacgaggtca tggtgggagc catgaaatct
    48181 ccaaaaacct tcactcgtga ggatattatc gagattaaca cccacggtgg gattgcggtg
    48241 accaatgaga ttctccagct agctatccgt gaaggagctc ggttggctga acctggtgaa
    48301 tttaccaaac gtgccttttt aaacggtcgc gtagatttga cacaggctga ggcggtcatg
    48361 gatatcatcc gcgctaagac agacaaggcc atgaacattg cggtcaaaca acttgatggt
    48421 tccctttctg atcttatcaa taatacccgt caagaaatcc ttaacacact tgcccaagtt
    48481 gaagtcaata tcgactatcc tgaatacgat gatgttgagg aagctactac tgccgttgtc
    48541 cgcgagaaga ctatggagtt tgagcaattg ctaactaatc tccttaggac agcccgtcga
    48601 ggtaaaattc ttcgggaagg aatttcaaca gctatcatcg gccgccccaa cgttggaaaa
    48661 tctagcctgc tcaacaacct cttgcgtgaa gacaaggcca tcgtcacaga cattgctggg
    48721 acaacacgtg atgtcatcga agaatacgtc aacatcaacg gtgtccctct caaattgatt
    48781 gacacagcag gtattcgtga aacggatgac atcgttgaac aaatcggtgt ggaacgttcg
    48841 aaaaaagccc tcaaggaagc tgacttggtt cttctagtac taaatgccag cgagccactg
    48901 acagcccaag accgacaact tcttgagatt agccaagata caaaccgcat tatacttcta
    48961 aataaaaccg acctgccaga agcgattgag acttcggaac tacctgaaga cgttattcgt
    49021 atttcagtcc ttaaaaacca aaacatcgat aagattgaag agcgaatcaa caacctcttc
    49081 tttgaaaatg ctggtttggt tgagcaagac gcaacctacc tgtccaatgc ccgtcatatt
    49141 tccttgattg aaaaggcagt tgaaagctta caagctgtta atgagggtct agaactgggg
    49201 atgccagttg atttgcttca agtagatttg acacgtactt gggaaatcct cggagaaatc
    49261 actggggatg ccgctccaga tgaacttatc acccaactct ttagccaatt ctgtttagga
    49321 aaataagaaa aatccatgat ccttcattcg gtcatggatt ttattgtctt tattagtaat
    49381 ctggtcttaa gacacctgtt acagttgcct tggtcgcttc gtagtcgcca tctacgacaa
    49441 ccttgataat gcgtttagca tcttcttctg gtgctggaac aagaggtaga cgagttggtc
    49501 cagcttcaaa tcccatgtag ttcaaaactg ccttaactgg agcaggactt ggataagaga
    49561 agagagcatt aaccttagga atgaatttac gttgaatagc tgcggctttc ttcatatcac
    49621 tttctgcaat ggcaataaac atctcgtgca tttcatcccc atttgtatga gaggcaacag
    49681 aaataacccc atccgcccca aggttcatgg catggaaagc atctccatcc tcaccagtat
    49741 agaccaagaa ctcttctggt ttgtgctcaa tcaagtaagc catattagcc aagctagtac
    49801 attctttgac accgataata tttggatgat cagccaagcg aagcatggtt tctggagtta
    49861 attcaacaac cacacgccct ggaatgttat agataataat tggtaggtca gaagcatctg
    49921 caatagcctt aaagtgctga tacatccctt cttgagaagg tttgttgtag taaggaacaa
    49981 tagcaagccc agctgcgaaa ccaccaaatt ccgctacttc tttgacaaac tcaatagagt
    50041 cacgcgtatc attagtacct acacccgcaa tcaaaggaac gcgtccattg acaacctttt
    50101 gtacagccgc aaacaactcc aactcctcat cgtgggtcaa agttggactc tcagcagtcg
    50161 ttcctgcgag aagaattcca tccgtatgat gggccaataa atgctcaatc aaggctggaa
    50221 tagcatcaaa gttaatggaa ccatcctcat ggaagggggt aataaaagct gtaatgattt
    50281 tacatttttt taaatcttga taagacacga aaacacctct ctatttcaaa gaaggagttc
    50341 atctgaactc ctaaacgata tgactatttt aattcaaatt tcaattcagc tgttggacga
    50401 accaatccac gttcatgaag agtttcagca atctgaactg agttccaagc agcacctttg
    50461 agaaggttat ctgaaacaac ccacatgtga attccttttt ctgcatccaa gtctttacgg
    50521 atacgaccaa caaaggtatc acgtgaacca actgcattga tggcttgagg atagatttga
    50581 tgaactacat catcttcaag aacagcacct gggaaggatg cgatagctgc tttgacttct
    50641 tcaattggag ccacttcctt tgtttcaata taaactgact cagagtgagc tgacaagact
    50701 ggaatacgca cacatgtcgc agatactgca atgctatcat cttccataat tttcttagtt
    50761 tccttggtca tcttcatctc ttcgtacgtg taatcattat cagtgaagac atcaatttgt
    50821 ggaagagcgt taaaggcgat aggataatgt ttcttgtcac cacctgaagg caagatttcc
    50881 gcatgcaaat cacgtggttt cactccatca ttcaagacct cacgaagttc acgttgtgtc
    50941 tcaagaattg ctcccatacc agcacctgaa acggcttgat aagttgaaac aatgatacgg
    51001 tccaagcccc atttttggcg aaccggctca agagccacca tcatttggat tgttgaacag
    51061 ttagggcagg caatgattcc gttgtgggca tcaagtgcat gagcattgac ctctggaaca
    51121 accaaaggaa catctggatt ttgacggaaa taagatgtat tatccactac taccacgcca
    51181 gcttttactg cgtatggtgc atacttagct gatgtcgaac cacctgctga aaagagagca
    51241 atatcaactc cttcaaaagc tgtttcagtc gtttcttcaa tcgtaatatc ttgatcttta
    51301 aatttcaatg acttacctgc tgaacgtgca gaagcaaggt aacggatttt atcgattgga
    51361 agtgttgatt cttccaacat ttttatcatc tgagcaccga cagcacctgt cgcgccgact
    51421 acagcaactg tatatcccat aaataacctc tttcggaatt ttctaaaaat ttctataata
    51481 gaagtattat actacttttt ccatgaattg caaagctttt tcatcatttt ttggaaaata
    51541 aaaatcccca atcgctagac tagggattaa gaggcatctt catgtgatga gcaggttcac
    51601 acaactcatc aaggtccgct cctgcgttat gacctcctta tgctcaatag tagcccgaag
    51661 actacctatc gactcatcgc atctactatt ctactaaaga gaatgacttt tgtcaacaga
    51721 cgaaactctt tatactcttc gaaaatctct tcaaacttcg tcagcgtcgc cttgccgtat
    51781 gtatggttac tgacttcgtc agtttcatct acaacctcaa aaacatgttt tgagctgact
    51841 tcgtcagttc tatctacaac ctcaaagcag tgctttgagc aacctgcggc tagtttccta
    51901 gtttactctt tgattttcat tgagtattag ttttatttac acaggtgcat aagaaatata
    51961 ttggaaaaat tgggggcaga cataacaaaa acccttgtaa atcaagggct tttctgtcta
    52021 tttaatgcta attgccggga ttgaaccggc gacctcatcc ttaccatgga tgcgctctgc
    52081 caactgagct aaatcagctt acttaagaag tatactatat tcaaaaaaac ttgtcaagtt
    52141 tccttagaaa ttttccatag gaaaaagcca ggtaagaact acctagctta tcttcttcta
    52201 tttacttaaa tcaattcgac gaccaatttt accaataata atcgctccaa taatcaatga
    52261 agcaaattca ccgattcctg ttgtaaacca agtaaggaag aatggtaatt ctgctacaat
    52321 atttaactct gcagcgatag taaacatgga aattgaaaag aggattgaaa agaagaaatg
    52381 atcttttcga atcaatccgt taaagaggta atccttgcta tattttgcaa aaagccaaac
    52441 acctaaactg aggaatacta aggttgaacc accaccaaca aagacatcta gcagtccgaa
    52501 gctaaagaaa ttagcaatca tacaaccgat ggtaactccg atgatgtact taggattgta
    52561 aaaagccata aagttcatca tttctgaaat acgaaactga taagcaccat agctgatggc
    52621 atttaggggc ggtgtgacag tcaaaacgac gtagatagca gcgacgattg caatatctgc
    52681 aacatcacga atagttaatt ttttcatctt ttctcctttg gcggttatcc gcgtgtaata
    52741 tgcttggtga aagaagctaa gcaccaaggg ttgattcatt caaccttact agtatagcac
    52801 aatagcctgc tttatgctat acttaaagca tgaaaaaacc tattcaaaaa ttttttaaca
    52861 atgaaatctt agcctatctc ttttttggcc ttgcgacaac tctagtttcg attctctcac
    52921 gactagtcat ttatcaacta agtcatcagg aactccttgc tacggccttg gcaaatatta
    52981 tcggtatctt atttgccttt atcacaaatg atacgattgt atttaagcaa aaaaagaaaa
    53041 atagacttat ccgtttagtg aaattttctc ttgctcgcct ttctactttt ctgttagact
    53101 tgtttttaac ttttctcttt gtaacccaat ttcctcacat catagggcaa ttcgtaactg
    53161 aaaacattga taagataaat gctattgaaa caataattgc acaaatattc attattatca
    53221 tcaattatat cttgagcaag gtctatattt ttagaaaata atgctccatt tatgagcctt
    53281 ttaattgcct tctataatga tttaggatac aatgaaacac gaaacattga aaggaaaaca
    53341 gtatgttaaa aaatctaaaa tcgttcttgc ttcgaggaaa tgttattgac cttgctgtcg
    53401 gtgttgtcat tgcctctgct tttggtgcta tcgttacttc acttgtaaac gacattatca
    53461 ctcctcttat tttaaatccc gctttgaaag ctgctaaagt cgaacgtatc gctcaacttt
    53521 cttggcatgg agtcggctat ggtaactttt taagtgctat tatcaatttt atctttgtgg
    53581 gtaccgccct cttctttatt atcaagggca ttgaaaaagc acagaaactg actggcataa
    53641 agaaagaaaa aactgccgaa aaaaaaccaa ccgaattgga agtccttcaa gaaataaaag
    53701 ctctccttga gaaaaaataa tcgattaaaa ggatctagcg caaagctaaa tccttttttc
    53761 tttactcttt gggtaacttg cctgcttttt caagcatttt tttgataaga taaggcatct
    53821 taacattctc ccgccctttt ttctcaatca gttttttcac aaattctggc atttgtaaat
    53881 cttcagattc agctaaaatg tttttcgtct cgtctgaagg aactaactca tcaaaggtct
    53941 cttcttctgg gagaaattcc ttaaactctt gattttcatt gactctaatt gtattgacca
    54001 aagcatcaat caaacgagaa tctgtatttg gcattggtgg acgatggtag tttaccccaa
    54061 attcctgaca taagtcataa cattccacat cattgtcaaa caagacctca atatgctcac
    54121 tgatgaaact aataggtaca aaaatataat ggtctggatg ttctgtctgt tctctgagat
    54181 actccaaaac atctggttta atccatggaa taccaatatc actctcactc tgccaagtgt
    54241 tggtatattg ttctgaactc aagcccagtt tttcagcgac tagcttgcta ttttcgaaaa
    54301 tttggtctat ataaggatca ccaaagtcca aggcaaaaat aggcacacta tgggctgaaa
    54361 agatgacttt aaagctgtct tgctttactt cttcttttaa aatcttagca atttcatctg
    54421 cccaatagtt taagagcgct tcttcctgat accagtcctt aataaccaaa aattgaattt
    54481 gtttgctttc taaaaatttt tcatagccca tgacagagta gaaagaataa tggggctcca
    54541 aaatcaagca aatacactgt tcaattccgt ctgcttccat ttgaccgatc acatctggaa
    54601 taaagggact ggaaaactta ttagcaaagt agacactgta ttcattcccc agcctagctt
    54661 ctaccaaggc aacctcttga cgggtaattt tttgcagagg cgtgcctcca attcgtacat
    54721 aattatcata gagagtctga atctcgtggt cttggggtct caccccacga cgaatatttg
    54781 tgaaaaaatc agctacacct tcaaaggtaa tctcttctgg tgaaccgaag gtcatcatta
    54841 aaattgcttt tttcatgact gcttccttgt gatgttttta tcaagtttat tttatcatta
    54901 attcatcgat aagtaaacgc taacataggg acattctcaa tcttctgtct tttgtttttc
    54961 tcttctttct atgatacaat ggaaaaaata aattcaaaag gagttttttt atgacttatc
    55021 caaatctctt ggaccgcttc ttaacctacg ttaaggtcaa cacgcgctct gatgaacact
    55081 ctactactac tccaagtaca cagagtcagg ttgacttcgc aacaaatgtc ctaattcctg
    55141 aaatgaaacg tgttggactg caaaatgttt actatctacc gaatggtttt gctattggaa
    55201 ccttgccagc caacgatccg tctttaacac gtaagattgg ttttatatcg cacatggata
    55261 ctgctgattt taatgctgaa ggagtcaatc cacaggtaat tgaaaactac gatggtggtg
    55321 tgattgaact agggaattct ggtttcaaac tcgatccagc tgacttcaag agtcttgaaa
    55381 aatatccagg acaaacgctc atcacaacag atggaacaag cttgctaggt gctgatgaca
    55441 agtcaggaat tgctgaaatt atgacagcca ttgaatatct aactgctcat cctgaaatta
    55501 agcactgtga gattcgtgtt ggttttggtc cagatgaaga aatcggtgtt ggtgccaata
    55561 aatttgatgc agaagatttt gatgtggatt ttgcctacac tgttgatggt ggtccactag
    55621 gtgaacttca gtacgagact ttctcagccg ctggtgctga attgcatttc caaggccgta
    55681 atgtccaccc tggtactgcc aaagggcaga tggtcaatgc ccttcagcta gcaattgatt
    55741 ttcataatca acttccagaa aatgaccgac ctgagttaac tgaaggttac caaggttttt
    55801 accatctaat agatgtgaca ggtagtgttg aggaggcgcg tgcaagctac atcattcgtg
    55861 attttgaaaa agatgccttt gaagcgcgta aagcatccat gcaatctatc gctgataaga
    55921 tgaatgaaga acttgggagc aaccgtgtca ctctcaactt gacagaccag tactacaata
    55981 tgaaagaagt cattgaaaaa gatatgactc caattaccat tgctaaagcc gttatggaag
    56041 atctaggtat cacgcctatt atcgaaccaa tccggggtgg aacagacggc tctaagattt
    56101 cctttatggg aatcccaact ccgaatatct ttgcaggtgg cgaaaatatg cacggacgtt
    56161 ttgaatacgt tagccttcag actatggaac gtgcagttga taccatcatt ggcatcgtag
    56221 cttataaagg ctaaaaagac gaggtagctc agctacttcg cctttctttt tattctactg
    56281 gtttttcttg atttccagta gttgtagaag attctgttgt ttcattttct gaagttgatt
    56341 cagcaggttt agaatctctt gtattgcttg gtttgttttc gtcgctagca gtttcaatgt
    56401 tagattctgc agttgcgttt ggttggttct cagcactggt gttatcacta tttgcttcag
    56461 catttcttgc tggacttgtt tcttcacttg cgctagcttt tgactggatt tgatgattca
    56521 aaactagaat agcttttgtc gattcaagta aagctgtttt gtctttactc ttagcagaaa
    56581 gttgatctaa taatgcatcc accttatcaa agtccgcatc agatccatta ttactttcta
    56641 aataagagtg aagcgacatg agaatatcgt agagtttttg atagagtaca agtgtctgag
    56701 aatcttgctc agcattttcc ttttcttgtt gaagggcgct agcgatacga gtcaagacat
    56761 cttttacctg actgtttact tcatccaagt ctgcatcagc cttgtttgtg gcagctttta
    56821 gattttctac ttcttctgcc aaggattgtc tgattccttc ttcatggatt tgttccaaga
    56881 gttgatttgc cttgttcaaa agactttcta cttcttcctt tctatctgtc gcagattatt
    56941 ggttgctatc taccatgtac tcctaaaaca ggagagttat aatccaagat tacaaggcct
    57001 tacagaaata agaaatccag ataagacaat gttcgtccaa gacgctattc gcttcgcaca
    57061 gcagcacgga ttcaatatac tttaatttta aagtttaggt gtcaagacct ctttttagtg
    57121 tgcccaaaat ttagagaagt aatcaatcaa ctaactttta tttttttcaa actttcagta
    57181 aactgaccta aagctaactc aatctgtctt tgtagatgct tctgctatca gctagaagtt
    57241 gatctacttt tgccaagact gccttctcat caaaagttcc aggttgatag ttggattgca
    57301 gggatggaat cttgtttttc aaagccgctt catatccctt agtttgaacc ttgatgtagt
    57361 gattgtggtc gccatgagga atcacaaaac cttctgaatc ttcacttata attcgattgg
    57421 catcaaaacc atgaccatct tcttcctcat ggtggacatg tagtgacgga ttacttaata
    57481 cagaactaga agaacttcct acctcttccg tgttagagtg tgatggggga ttgttaagag
    57541 atgacttagg aatatagtga tagtgatccc catgtcttac tatataagca tcacctgtat
    57601 ctctgacaat atcattaggg ttaaagacat atgtggctgc taattcacct gccgacaagt
    57661 cactctcagg aatgaaatga tagtgaccac catgtggtac tatagtagat tgaaatagaa
    57721 tatgagcaaa ttgataaggg gattttaaag taatttctaa caatgattta gaaactatga
    57781 tgtgctattc taaattcaac tcactatata taaccatcat cggtagtata acgtccctgt
    57841 aattttgcta cagatacttc tgcactagct cctttatcgt ctttaccatg ttcttgtttt
    57901 tggcgattga tttcatcttt tgttcgtaca ttttctgcat gagcttgatc tttaaggtaa
    57961 acataatact ttccatctac cttaataata tatcctccct taacctaact gacgatatct
    58021 tgatctttcg gctgatagtt gggggctttc attaatagct cttcactaaa gagcgcatca
    58081 aaaggaactt taccattata gtagtgataa tgatcgccat gagaagttac ataaccttga
    58141 tctgtaatct taataacaat ttgttttgct tgaattcctt ctttttgact aacctagtct
    58201 ggagtcaaat tttcagtctt cttagtgtct ttattactgt ttacatatga aacacgattt
    58261 ttatctgtat tggcctgtta gctatgttgg ttcagagcat aaacacacag acttaaggaa
    58321 aggataacaa cagatccagc tgctatatat ttctttttaa atttcataat tacctcattt
    58381 ctataattat ttatatgatg tcttcattat taaatgatta aataaattaa ttaaccaatt
    58441 aattaactag taaatattcc acctcttttt aagttgtatg tcaagaaatt ttatatatta
    58501 ataataaaat gaaattctcc caaagtcaga gttttatttc taacttttga gagaacttca
    58561 tttttgattc agactttttc tactgctatt ccttacgcta tgagatcaga taaattcttt
    58621 tttatcactt ctccacttgg caatcttaat tcaatcgttc catccatatt gaatataaca
    58681 ctatctaagc ctaatccgta actagctgta aatttttcta atttttcttg tacaggatct
    58741 actgctggag cttcctctaa tgctggatct aacatagggt cactccccac attcccttct
    58801 ggattcaaca ttccattatc cgttgagttt tctggtttta caggtttttc gtttggtgcc
    58861 tctggtaaag aatctgctgg tttattttct gttggttggt tctcaactgt tccagtagat
    58921 acttttccag tttcagatgg tttattttca ccatttcctt gaggtgcttc tcctgtaaaa
    58981 tctgccatat tctttttaat gacttctccc gatggtaaat ataattcaat tgttccgtcc
    59041 atattaaaca agacattttc tagcttcatc ccataacttt cagcaaattt tgctactttt
    59101 tcttgtacag gatccactgt aggaacttct tctaacgttg aatcactagt actgttccca
    59161 gtttcaggaa gcttttcttt ttctaccttc tcactagtct ttggttcttc taccttttca
    59221 tcaagttttg agttttcttg tgctttattc cttttaaatt gtggtagaat acttggttta
    59281 tcagtttgat tttctttttc caagataggt acttccacaa tataagtcga ttgattgtcc
    59341 aaataagcat ttgccatgaa ggttacagga attttatttc cggccgttct ggttgttcct
    59401 tggtttaatt tcggaatcgg taatttaatt tcaccaactt tatagttatt ttctaaataa
    59461 gcatttccat gaaattcatc aaacactctg actaaagcat cagttccttt aggcactgca
    59521 aattgagggt tcactcttaa ataagtatcc cctgcatgga aaggatagaa aatcgtttga
    59581 ctggccattt tgtaagctaa agaggttgga actgtaaatg taccatcata acttacttct
    59641 ggataatctt ttgaagcgat agtatactta aatgtttgtc ctggtaaata aggttgatct
    59701 aattcaaagt ttgcaatatt ccctactcct tctccaaata ctttaccaga tactttctcc
    59761 aatacttttc catctggtgt tattaatttt actagcatat tgatacctaa ttttttttcc
    59821 aattcaggcg gaaaactaaa agaaacgcgt ttttgaccat tggctagagt aaagttttga
    59881 ttattaaacg tactattttt taacaaatta acaacattcg ttaattcttc tccagtataa
    59941 actttattcc cttctttttt agcaactcct tcttcgggtt taaacagttc atagttactg
    60001 tgagaatgac caattccaac cggtttatgt tcatcaatcg gatctgcatg atggtgatct
    60061 ccatgcggat aaataatcgc atttttttct ttattcacga caatactttc acgtttgaca
    60121 ccatattgtt tcataatgcc agcaattttt tcttcgattt ttttatctaa atctttcatt
    60181 tctttggcat tacctggata atcctgttca tgagatgaca aagaatctaa tccattatga
    60241 ctagttttaa cttcctctaa atgtttttgc gcagccttaa tttgctcttc tgtcaagtcc
    60301 ttcttgaaga aataatgatt gtggtctccg tgactcatga caaaacctga ttcatcttca
    60361 gcgataatac gattagcatc aaatccgtat ccatcttctt catgtttctc atgtgaagtt
    60421 cctggattga ttggaagaga tggagaaggt gttgctagac tattgtttgg aagagtcggt
    60481 tgcccaattt gatttgattt tggaatgtaa tggaaatgat caccatgtct tacaatataa
    60541 gctgtagccg tttcttcaac gatatctttt ggattaaaaa tataaccatc agatgctgaa
    60601 gagagtttct tacttgtcgt taaagaagaa ggattgcttg aaagactgcc tagactagac
    60661 actacttcat taggttttgc atttgtagaa actgtagaac cagttccact gataggcacc
    60721 attctggcaa tcttttcttc taaggcagaa agcttgctgt aaggaataaa gtggtaatgg
    60781 tcgccatgcg gaatcgcaac tccatttggt gtacgactga taatcttagc agggtcaaag
    60841 accaggccat ctgattcact gtaacgttgg gcgctaggtg aatcatagag ttccttcaaa
    60901 agactctgga gattttcaga tttatttgct ggcttgctag ttgatccttt tgctacagat
    60961 tgcgtgttat tgtcactagc tgttgaagaa tagcttaact gactcggttg catatttttt
    61021 ccagccagat gtgctttagc tgctgctaat tcactagcag ataaatcgct tttgggaatg
    61081 tagtgatagt gacctccatg aggaacgata taagcattac ccgtatcttc gataatatca
    61141 gctggattaa agacataacc atcatttgtc gtatatcgtc cctgagacct tgctacagca
    61201 acattagagt taaccttctc attatctttg acatgttctt gtttttgacg attgatttca
    61261 tctttagttc gaacattatc agcatgagct gcatctttca ggtagacata atattttcca
    61321 tcgaccttga tgatataacc acccttgact tcattgacaa tatcagcgtc tttaagttga
    61381 tagtttggat ccttcatcaa gagttcttca ctaaagaggg catcataagg aactttccca
    61441 ttatagtaat gatagtggtc accgtgtgac gttacatagc cctgatctgt aattttgatt
    61501 acaatttgct cagcctgaat tccttctttc tggctaacct ggtctggtgt caagttttca
    61561 cttttctgac ttgactggct gccatccaca taagagacac gattattgtc cttattttcc
    61621 tgcgaacgat gctggtttag tgcataggca catagactca aggatacgat aacagctgat
    61681 ccagctgcta tatatttttt actaaatttc ataaatccct catttcaata aatgatgaag
    61741 tttttttctc aacttctttt actttattaa atagttttct aaaccgatta tttaaccatt
    61801 taattaacca gtaaatagtc tactatttaa aattactttt gtcaagtttc tgttacgttt
    61861 ttctaaaaaa gagaagtaac acgaaaggtt acttctccat aaaatatgct ccattcattt
    61921 tactactgta taggagccgg ttgactttct tttaacaaag ccaagagact atctacttct
    61981 gctgaaatag tattattatc tttcgttccg agaagaagac tactttttag accagtcaat
    62041 gtctccatag cattttgtct aatactagaa tctgttactt tttctagcaa ggcctccgcc
    62101 tctgctatct tagcgttaat aacagaatgc tctacttgag gaatttcagc ctcatctgta
    62161 gtatcttcag cttcttcctc tgtctcttcc gtatcagtgc ttggtttata aagattatct
    62221 gctgaaggat ttaaaccagc gtgattctct ttttcatcag attcagggtg agttggctca
    62281 cttacttcat catgttcctt atcttcctca ggtttttctg tctgaggttt
//
LOCUS       DAVAGB010000006        57743 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVAGB010000006 DAVAGB010000000
VERSION     DAVAGB010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 57743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57743
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.006"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            145..6831
                     /locus_tag="VQO19_000441"
     CDS             145..6831
                     /locus_tag="VQO19_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HET1348750.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDVDVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVESPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNTGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGLTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SSQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSL
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSQRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEIQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLSVEWEEVPAEN
                     LTKAGQFTVRGRVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSARPSTNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPSKLVLERYVGPGFEVPTYYSNYQAYESGHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGKERIFT
                     AINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSEASQTN
                     KAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(7079..7935)
                     /locus_tag="VQO19_000442"
                     /pseudo
     CDS             complement(7079..7935)
                     /locus_tag="VQO19_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8146..8505)
                     /locus_tag="VQO19_000443"
     CDS             complement(8146..8505)
                     /locus_tag="VQO19_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HET1348751.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLTLSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYVEMIVELFLMK"
     gene            8597..9553
                     /locus_tag="VQO19_000444"
     CDS             8597..9553
                     /locus_tag="VQO19_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HET1348752.1"
                     /translation="MKVIKSYNTLNDYYRKLFGEKTFKVPIDAGFDCPNRDGTVAHGG
                     CTFCTVSGSGDTIVAPDAPIREQFYKEIDFMHRKWPDVRKYLVYFQNFTNTHEKVEVI
                     RERYEQAINEPGVVGINIGTRPDCLPDETIEYLAKLSERMHVTVELGLQTTYEATSDL
                     INRAHSYELYVETVKRLRKYPKIEIVSHLINGLPGETHEMMVENVRRCVTDNDIQGIK
                     LHLLHLMTNTRMQRDYHEGRLQLMSQDEYVKVICDQLEIIPKHIVIHRITGDAPRDML
                     LGPMWSLNKWEVLNAIETEMRRRGSVQGCKVVKQEFENEKTT"
     gene            9537..10094
                     /locus_tag="VQO19_000445"
     CDS             9537..10094
                     /locus_tag="VQO19_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET1348753.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDIVVDATMGNGHDTLFLAKLAKKVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRLQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            10087..10341
                     /locus_tag="VQO19_000446"
     CDS             10087..10341
                     /locus_tag="VQO19_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348754.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            10353..12407
                     /locus_tag="VQO19_000447"
     CDS             10353..12407
                     /locus_tag="VQO19_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HET1348755.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            12586..13446
                     /locus_tag="VQO19_000448"
     CDS             12586..13446
                     /locus_tag="VQO19_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HET1348756.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            13657..14367
                     /gene="ccdA2"
                     /locus_tag="VQO19_000449"
     CDS             13657..14367
                     /gene="ccdA2"
                     /locus_tag="VQO19_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET1348757.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGFLVLFGNASILSQLFE"
     gene            14387..14953
                     /locus_tag="VQO19_000450"
     CDS             14387..14953
                     /locus_tag="VQO19_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HET1348758.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            14964..16076
                     /gene="msrB"
                     /locus_tag="VQO19_000451"
     CDS             14964..16076
                     /gene="msrB"
                     /locus_tag="VQO19_000451"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET1348759.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            16344..17081
                     /locus_tag="VQO19_000452"
     CDS             16344..17081
                     /locus_tag="VQO19_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET1348760.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            17078..18769
                     /locus_tag="VQO19_000453"
     CDS             17078..18769
                     /locus_tag="VQO19_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET1348761.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIDTGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYHMKIDSRPQKGTKVEIYINRIETS"
     gene            18885..19448
                     /locus_tag="VQO19_000454"
     CDS             18885..19448
                     /locus_tag="VQO19_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HET1348762.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGHIG
                     KESSQEIGELIVETILDILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKF"
     gene            19470..25136
                     /locus_tag="VQO19_000455"
     CDS             19470..25136
                     /locus_tag="VQO19_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET1348763.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSITNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEQAGEPVAPREDEKAPVEPEKQPEAPEEEKAVEETPKQEESTPDTKAEETVEPKEE
                     TKTAKGTQEEGKEGQAPVQEVNPEYKVTTGTVEKSTESELDFTTEVVPDDTKYVDEEV
                     VERQGSKGVQVTKTTYETVEVVETDKVLSTTTEVKTPVVPKVVKKGTKPVEGTAVETR
                     EEVIPFATKEQEDGTLKRGTRQVAQEGVNGKKQITETYKTIRAEKTNEAPTVEETVLQ
                     APQDEIIKKGTKGLEKPTLEWVKTDKDVLKKSATASYTLNKPDGVEIKSIKVALKDNT
                     GTVIKEVTVEENNLNVTLDNLKYYQGYTLSTTMVYNRGEGEETETLEDKEVQLDLKKV
                     EIKNIKETSLMSVDDAGVETDKSLLTEKPTDVAPLYLRVTTHDNKVTRLAVDKIEEVE
                     EDGKTLYKVTAKAPDLVQRNADNTLSEEYVHYFEKQLPKIGNVYYNFNELITDMQKTP
                     NGEFKLGADLNAVNVPTPNKSYVTAKFTGKLYSEGDKHYTIHNLARPLFAQAENAHIH
                     DINLGNVNINMPWANKTAPLGEMFKKSTIENVKVTGNVVGNNDVTGMVNKLDESDMRN
                     VAFIGNITSVGSAGWWSGGLVSESWRSNTDNSYIDTTIKGNKAKVGGLIAKLNHGADP
                     RDVGARGRLKNSVAKGTIDVRDPQETGGLLHSNWSWGLAENNITMMKVKNGGEILYGS
                     RDAEDDDYFGANWVRNNNAFVNGISEGKQSYSRSSRWKGISEDEAKTRIAKMGITAHE
                     YEITQHLTDKLNRAAFKEDTYKTTQDYKTERELAYRNIEKLQPFYNKEWIINQGNKLT
                     DGSNLMIKEVLSVIGMKNGQFVTDLSDIDKIMIHYADGTKEEKTVTRKADSKVQQIRE
                     YSVEGLGDVVYTPNMVEKDRAQLITDIKAKLDSVQLISPEVRNLMDKRGKAHENTDER
                     RNGYIRNLFLEESLDEVKGNLDKLVKALVENEDHQLNGDEAAMKALVKKVEDNKAKIM
                     LGLAYLNRYYGFKYDEKSMKDIMMFKPDFYGKNVSVLDFLIRVGSREHNIKGNRTLEA
                     YREVIGGTIGIGELNGFLNYNMRLFTEETDINTWYKKAVSHTNYIVEKQSSNPAFANK
                     KYRLYENLNNGEHGKYILPLLTTKKAHMFLISTYNTLAFSAFEKYGKNTEAEREAFKK
                     EIDLRAQEQINYLDFWSRLAADNVRDRLLKSENMVPSAIWDNQEVPGHGWADRMGHNK
                     NGDYAPVREFYGPTGKWHGYNGTGAYAYIFTNPQNSEAVYYIISSMISDFGTSAFTHE
                     TTHINDRMAYLGGWRHREGTDVEAFAQGMLQSPAVSSPNGDYGALGLNMAYKRENDGN
                     QWYNYDSNKLDSRAKIDHYMKNYNEALMMLDHLEADAVIAKNNGDNNKWFKKMDKKWR
                     ENANRNGLVGQPHQWDLLRDLNEEENKKKLTSIDDLVDGNYVTKHNMPGNKHYRAEGF
                     DTAYQTVNMMAGIYGGNTSKSAVGSISFKHNTFRMWGYFGYLDGFVGYASNKYKDAAN
                     KENKGLLGDDFIIKKVSDGKFDSLEAWKKEWFKEVKAKGEKGFVAIEIDGKTITNYAE
                     LRELFDKAVEADLKAGNSNQTVALKEKVYKQLLQKSDGFVGNLFKA"
     gene            25211..26932
                     /gene="pabB"
                     /locus_tag="VQO19_000456"
     CDS             25211..26932
                     /gene="pabB"
                     /locus_tag="VQO19_000456"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HET1348764.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKVPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            26933..27550
                     /locus_tag="VQO19_000457"
     CDS             26933..27550
                     /locus_tag="VQO19_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET1348765.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            27600..28590
                     /locus_tag="VQO19_000458"
                     /pseudo
     CDS             27600..28590
                     /locus_tag="VQO19_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            28725..29684
                     /locus_tag="VQO19_000459"
     CDS             28725..29684
                     /locus_tag="VQO19_000459"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HET1348766.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENTFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            29782..30621
                     /locus_tag="VQO19_000460"
     CDS             29782..30621
                     /locus_tag="VQO19_000460"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HET1348767.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(30669..30839)
                     /locus_tag="VQO19_000461"
     CDS             complement(30669..30839)
                     /locus_tag="VQO19_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HET1348768.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            30960..31844
                     /gene="miaA"
                     /locus_tag="VQO19_000462"
     CDS             30960..31844
                     /gene="miaA"
                     /locus_tag="VQO19_000462"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HET1348769.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIQSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPYEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            31837..33075
                     /gene="hflX"
                     /locus_tag="VQO19_000463"
     CDS             31837..33075
                     /gene="hflX"
                     /locus_tag="VQO19_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HET1348770.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            33068..33691
                     /locus_tag="VQO19_000464"
     CDS             33068..33691
                     /locus_tag="VQO19_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HET1348771.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            33706..34635
                     /locus_tag="VQO19_000465"
     CDS             33706..34635
                     /locus_tag="VQO19_000465"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HET1348772.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            34656..35411
                     /locus_tag="VQO19_000466"
     CDS             34656..35411
                     /locus_tag="VQO19_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET1348773.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(35465..36373)
                     /locus_tag="VQO19_000467"
     CDS             complement(35465..36373)
                     /locus_tag="VQO19_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET1348774.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            36437..36706
                     /locus_tag="VQO19_000468"
     CDS             36437..36706
                     /locus_tag="VQO19_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HET1348775.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            36706..37086
                     /locus_tag="VQO19_000469"
     CDS             36706..37086
                     /locus_tag="VQO19_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET1348776.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNKEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            37175..37402
                     /locus_tag="VQO19_000470"
     CDS             37175..37402
                     /locus_tag="VQO19_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348777.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(37442..38167)
                     /locus_tag="VQO19_000471"
     CDS             complement(37442..38167)
                     /locus_tag="VQO19_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET1348778.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLKGDILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQTFQKGIVFLDGTIC
                     KPARLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            38329..40170
                     /gene="typA"
                     /locus_tag="VQO19_000472"
     CDS             38329..40170
                     /gene="typA"
                     /locus_tag="VQO19_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HET1348779.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            40190..40444
                     /locus_tag="VQO19_000473"
     CDS             40190..40444
                     /locus_tag="VQO19_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HET1348780.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            40809..41108
                     /locus_tag="VQO19_000474"
     CDS             40809..41108
                     /locus_tag="VQO19_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET1348781.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSIVSRWNGHSDKGEAPAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            41179..43200
                     /locus_tag="VQO19_000475"
     CDS             41179..43200
                     /locus_tag="VQO19_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET1348782.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFIYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDIENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVRPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNILYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            43202..43843
                     /locus_tag="VQO19_000476"
     CDS             43202..43843
                     /locus_tag="VQO19_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1348783.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            43947..45299
                     /locus_tag="VQO19_000477"
     CDS             43947..45299
                     /locus_tag="VQO19_000477"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HET1348784.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVIPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELAIQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            45301..46359
                     /locus_tag="VQO19_000478"
     CDS             45301..46359
                     /locus_tag="VQO19_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HET1348785.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDKNTPEPDELVDIQTHFNPKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELRQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            46369..47535
                     /gene="divIB"
                     /locus_tag="VQO19_000479"
     CDS             46369..47535
                     /gene="divIB"
                     /locus_tag="VQO19_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HET1348786.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEESES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFLSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKATIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESN"
     gene            47801..48502
                     /gene="pyrF"
                     /locus_tag="VQO19_000480"
     CDS             47801..48502
                     /gene="pyrF"
                     /locus_tag="VQO19_000480"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HET1348787.1"
                     /translation="MREHRPIIALDFPSFEVVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            48536..49168
                     /locus_tag="VQO19_000481"
     CDS             48536..49168
                     /locus_tag="VQO19_000481"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HET1348788.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVDAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            49348..49751
                     /locus_tag="VQO19_000482"
                     /pseudo
     CDS             49348..49751
                     /locus_tag="VQO19_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            49847..50611
                     /locus_tag="VQO19_000483"
     CDS             49847..50611
                     /locus_tag="VQO19_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348789.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STVIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSAHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            50611..51363
                     /locus_tag="VQO19_000484"
     CDS             50611..51363
                     /locus_tag="VQO19_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348790.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            51373..52071
                     /locus_tag="VQO19_000485"
     CDS             51373..52071
                     /locus_tag="VQO19_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348791.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFQ
                     SIFYFTRQKRRFIE"
     gene            52068..52715
                     /locus_tag="VQO19_000486"
     CDS             52068..52715
                     /locus_tag="VQO19_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1348792.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(52802..53673)
                     /locus_tag="VQO19_000487"
                     /pseudo
     CDS             complement(52802..53673)
                     /locus_tag="VQO19_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(53685..54443)
                     /locus_tag="VQO19_000488"
     CDS             complement(53685..54443)
                     /locus_tag="VQO19_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET1348793.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGPSGCGK
                     STLLRCLNGLESIQGGDILLDGQSIVENKKDFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKAQGRDKKEVTEEALQLLERVGLLDKQHSFARQLSGGQKQRVAIVRALLMHPE
                     IILFDEVTASLDPEMVREVLELINDLAQEGRTMILVTHEMQFAQAITDRIIFLDQGKI
                     AEEGTAQAFFTNPQTKRAQEFLNVFDFSQFGSYL"
     gene            complement(54444..54645)
                     /locus_tag="VQO19_000489"
                     /pseudo
     CDS             complement(54444..54645)
                     /locus_tag="VQO19_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598330.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter permease"
     gene            complement(54742..55122)
                     /locus_tag="VQO19_000490"
     CDS             complement(54742..55122)
                     /locus_tag="VQO19_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154138.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HET1348794.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIIFTLW
                     GTAEMGDLVRGAITSLPKHQFESG"
     gene            complement(55082..55750)
                     /locus_tag="VQO19_000491"
     CDS             complement(55082..55750)
                     /locus_tag="VQO19_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET1348795.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRIPV
                     LAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVVLPSFSANVIFLIKKTSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTRHAGFGNPST
                     LSRK"
     gene            55977..56123
                     /locus_tag="VQO19_000492"
     CDS             55977..56123
                     /locus_tag="VQO19_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HET1348796.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            56251..57741
                     /gene="lysS"
                     /locus_tag="VQO19_000493"
     CDS             56251..57741
                     /gene="lysS"
                     /locus_tag="VQO19_000493"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HET1348797.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLKEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
BASE COUNT        17616 a        10615 c        12831 g        16681 t
ORIGIN      
        1 catacatacg gcaaggcgac actgacgaag tttgaattgg attttcgcag agtgtaaatt
       61 gttgaaacta ggttgtcata ccatgtatac cacttgggct ttggtagtag ctaactgcac
      121 taaatataat ataaggaggg ttttatgggg aaaggccatt ggaatcggaa aagagtttat
      181 agcattcgta agtttgctgt gggagcttgc tcagtaatga ttgggacttg tgcagttcta
      241 ttaggaggaa atatagctgg agaatctgta gtttatgcgg atgaaacact tattactcat
      301 actgctgaga aacctaaaga ggaaaaaatg atagtagaag aaaaggctga taaagctttg
      361 gaaactaaaa atgtagttga aaggacagaa caaagtgaac ctagttcaac tgaggctatt
      421 gcatctgaga agaaagaaga tgaagccgta actccaaaag aggaaaaagt gtctgctaaa
      481 ccggaagaaa aagctccaag gatagaatca caagcttcaa gtcaagaaaa accgctcaag
      541 gaagatgcta aagctgtaac aaatgaagaa gtgaatcaaa tgattgaaga caggaaagtg
      601 gattttaatc aaaattggta ctttaaactc aatgcaaatt ctaaggaagc cattaaacct
      661 gatgtagacg tatctacgtg gaaaaaatta gatttaccgt atgactggag tatctttaac
      721 gatttcgatc atgaatctcc tgcacaaaat gaaggtggac agctcaacgg tggggaagct
      781 tggtatcgca agactttcaa actagatgaa aaagacctca agaaaaatgt tcgccttact
      841 tttgatggcg tctacatgga ttctcaagtt tatgtcaatg gtcagttagt ggggcattat
      901 ccaaatggtt ataaccagtt ctcatatgat atcaccaaat accttcacaa agatggtcgt
      961 gagaatgtga ttgctgtcca tgcagtcaac aaacagccaa gtagccgttg gtattcagga
     1021 agtggtatct atcgtgatgt gactttacaa gtgacagata aggtgcatgt tgagaaaaat
     1081 gggacaacta ttttaacacc aaaacttgaa gaacaacaac atggcaaggt tgaaactcat
     1141 gtgaccagca aaatcgtcaa tacggacgac aaagaccatg aacttgtagc cgaatatcaa
     1201 atcgttgaac gaggtggtca tgctgtaaca ggcttagttc gtacagcgag tcgtacctta
     1261 aaagcacatg aatcaacaag cctagatgcg attttagaag ttgaaagtcc aaaactctgg
     1321 accgttttaa atgacaaacc tgccttgtac gaattgatta cgcgtgttta ccgtgacggt
     1381 caattggttg atgctaagaa ggatttgttt ggttaccgtt actatcactg gactccaaat
     1441 gaaggtttct ctttgaatgg tgaacgtatt aaattccatg gagtatcctt gcaccacgac
     1501 catggggcgc ttggagcaga agaaaattat aaagcagaat accgtcgtct caaacaaatg
     1561 aaggagatgg gagttaactc catccgtaca acccacaacc ctgctagtga gcaaaccttg
     1621 caaatcgcag cagaactagg tttactcgtt caggaagagg cctttgatac ttggtatggt
     1681 ggcaagaaac cttatgacta tggacgtttc tttgaaaaag atgccactca cccagaagct
     1741 cgaaaaggtg aaaaatggtc tgattttgac ctacgtacca tggtcgaaag aggcaaaaac
     1801 aaccctgcta tcttcatgtg gtcaattggt aatgaaatag gtgaagctaa tggtgatgcc
     1861 cactctttag caactgttaa acgtttggtc aaggttatca aggatgttga taagactcgc
     1921 tatgttacca tgggagcaga taaattccgt ttcggtaatg gtagcggagg gcatgagaaa
     1981 attgctgatg aactcgatgc tgttggattt aactattctg aagataatta caaagccctt
     2041 agagctaagc atccaaaatg gttgatttat ggatcagaaa catcttcagc tacccgtaca
     2101 cgtggaagtt actatcgccc tgaacgtgaa ttgaaacata gcaatggacc tgagcgtaat
     2161 tatgaacagt cagattatgg aaatgatcgt gttggttggg ggaaaacagc aaccgcttca
     2221 tggacttttg accgtgacaa cactggctat gctggacagt ttatctggac aggtacggac
     2281 tatattggtg aacctacacc atggcacaac caaaatcaaa ctcctgttaa gagctcttac
     2341 tttggtatcg tagatacagc cggcattcca aaacatgact tctatctcta ccaaagccaa
     2401 tgggtttctg ttaagaagaa accgatggta caccttcttc ctcactggaa ctgggaaaac
     2461 aaagaattag catccaaagt agctgactca gaaggtaaga ttccagttcg tgcttattcg
     2521 aatgcttcta gtgtagaatt gttcttgaat ggaaaatctc ttggtcttaa gactttcaat
     2581 aaaaaacaaa ccagcgatgg gctgacttac caagaaggtg caaatgctaa tgaactttat
     2641 cttgaatgga aagttgccta tcaaccaggt accttggaag caattgctcg tgatgaatct
     2701 ggcaaggaaa ttgctcgaga taagattacg actgctggta agccagcggc agttcgtctt
     2761 attaaggaag accatgcgat tgcagcagat ggaaaagact tgacttacat ctactatgaa
     2821 attgttgaca gccaggggaa tgtggttcca actgctaata atctggttcg cttccaattg
     2881 catggccaag gtcaactggt cggtgtagat aacggagaac aagccagccg tgaacgctat
     2941 aaggcgcaag cagatggttc ttggattcgt aaagcattta atggtaaagg tgttgccatt
     3001 gtcaaatcaa ctgaacaagc agggaaattc accctgacag cccattcaga tctcttgaaa
     3061 tctagtcaag tcactgtctt tactggtaaa aaagaaggac aagagaagac tgttttgggg
     3121 acagaagtgc caaaagtaca gaccattatt ggagaggcac ctgaaatgcc taccactgtt
     3181 ccgtttgtat acagtgatgg tagccgtgca gaacgtcctg taacctggtc tttagtagat
     3241 gtgagcaagc ctggtattgt aacggtgaaa ggtatggctg acggacgaga agtagaagct
     3301 cgtgtagaag tgattgctct taaatcagag ctaccagttg tgaaacgtat tgctccaaat
     3361 actgacttga attctgtaga caaatctgtt tcttatgttt tgactgatgg aagtgtacaa
     3421 gagtacgaag tagatagctg ggagattacg gaagtagata aagccaaact ttcagtagct
     3481 ggatcacgta ttcaaatgac tggtcagtta gctggagaaa ctattcatgc aacccttgtg
     3541 gtagaagaag gaaatgctgc agcacctgta gtgccaactg ttactgttgg aggtgaggca
     3601 gtaacaggtc ttactagtcg acaaccaatg caatatcgta ctctatctta tggtgcccaa
     3661 ctgccagaag tcacagcaag tgctgaaaat gctgatgtga cagttcttca agcaagcgca
     3721 gcaaacggca tgcgtgcgag catctttatt cagcctaaag atggtggtcc tcttcaaacc
     3781 tatgcaattc aattccttga agaagcgcca aaaattgctc acttgagttt gcaagtggaa
     3841 aaagctgaca gtctcaaaga agaccaaact gtcaaattgt cggttcgagc tcactatcaa
     3901 gatggaacgc aagctgtatt accagctgac aaagtaacct tctctacaag tggtgaaggg
     3961 gaagtcgcaa ttcgtaaagg aatgcttgag ttgcataagc caggagcagt cactctcaaa
     4021 gcggaatatg agggagctaa aggccaagtt gaactcacta tccaagccaa tactgagaag
     4081 aagattgcgc aatctatccg tcctgtaaat gtagtcacag atttgcatca aaaacctact
     4141 cttccaacaa cagtaacggt tgagtatgac aaaggtttcc ctaaagctca caaagtcact
     4201 tggcaagcta ttccgaaaga aaaactagac tcctatcaaa catttgaagt actaggtaaa
     4261 gttgaaggaa ttgaccttga agcgcgtgca aaagtctctg tagaaggtat cgtttcagtt
     4321 gaagaagtca gtgtgacaac tccaatcgca gaagcaccac aattaccaga aagcgttcgg
     4381 acatatgatt caaatggtca cgtttcatca gctaaggttg catgggatgc gattcgtata
     4441 gagcaatacg ctaaggaagg tgtctttaca gttaatggtc gcttagaagg tactcaatta
     4501 acaactaaac ttcatgttcg cgtatctgct caaactgagc aaggtgcaaa catttctgac
     4561 caatggaccg gttcagaatt gccacttgcc tttgcttcag attcaaatcc aagcgaccca
     4621 gtttcaaatg ttaatgacaa gctcatttcc tacaataacc aaccagccaa tcgttggaca
     4681 aactggaatc gtagtaatcc agaagcttca gtcggtgttc tgtttggaga ttcaggtatc
     4741 ttgagccaac gctccgttga taacttaagc gttggcttcc atgaagacca tggagttggt
     4801 gcaccgaagt cttatgtgat tgagtattat gttggtaaga ctgtcccaac agctcctaaa
     4861 aaccctagtt ttgttggtaa tgaggaccat gtctttaatg attctgccaa ctggaaacca
     4921 gttactaatc taaaagcccc tgctcaactc aaggctggag aaatgaacca ctttagcttt
     4981 gataaagttg aaacctatgc tgttcgtatt cgcatggtga gagcagacaa caaactagga
     5041 acgtctatca cagagataca aatctttgcg aaacaagttg cggcagccaa gcaaggacaa
     5101 acaagaatcc aagttgacgg caaagactta gcaaatttca accctgattt gacagactac
     5161 taccttgagt ctgtagatgg aaaagttccg gcagtcacag caagtgttag caacaatggt
     5221 ctcgctaccg tcgttccaag cgttcgtgaa ggtgagccag ttcgtgtcat cgcgaaagct
     5281 gaaaatggcg acatcttagg agaataccgt ctgcacttca ctaaggataa gaacttactt
     5341 tctcataaac cagttgctgc ggttaaacaa gctcgcttgc tacaagtagg tcaagcactt
     5401 gaattgccga ctaaggttcc agtttacttc acaggtaaag acggctacga aacaaaagat
     5461 ttgtcagttg aatgggaaga agttccagca gaaaatctga caaaagcagg tcaatttacc
     5521 gttcgaggcc gtgtccttgg tagtgacctt gttgctgagg tcactgtacg agtgacagac
     5581 aaacttggtg aggctctttc agataaccct aactatgatg aaaacagtaa ccaggccttt
     5641 gcttcagcaa ccaatgatat tgacaaaaac tctcatgacc gcgttgacta tctcaatgac
     5701 ggagatcatt cagaaaatcg tcgttggaca aactggtctg caagaccgtc taccaatcca
     5761 gaagtatcag cgggtgtgat cttccgtgaa aatggtaaga ttgtagaacg gactgttgct
     5821 caagccaaac ttcacttctt tgcagatagt ggtacggatg caccatctaa actcgtttta
     5881 gaacgctatg tcggcccagg ctttgaagta cctacctact attcaaacta ccaagcctac
     5941 gaatctggac atccatttaa caatccagaa aattgggaag ctgtgcctta tcgtgcggat
     6001 aaagacatcg cagctggtga tgaaatcaac gtaacattta aagctgtcaa agccaaagcc
     6061 atgagatggc gtatggagcg taaagctgac aagagcggtg ttgcgatgat tgagatgacc
     6121 ttccttgcac caagtgaatt gcctcaagaa agcactcaat caaagattct tgtagatgga
     6181 aaagaacttg ctgatttcgc tgaaaatcgt caagactatc aaattaccta taaaggtcaa
     6241 cggccaaaag tctcagttga agaaaacaat caagtagctt caactgtggt agatagtgga
     6301 gaagatagcc ttccagtact tgttcgcctc gtttcagaaa gtggaaaaca agtcaaggaa
     6361 taccgtatcc agttgactaa ggaaaaacca gtttctgctg tacaagaaga tcttccaaaa
     6421 ctcgaatttg ttgaaaaaga tttggcctac aagacagttg agaaaaaaga ttcaacactg
     6481 tatctaggtg aaactcgtgt agaacaagaa ggaaaaactg gtaaagaacg tatctttaca
     6541 gcgattaatc ctgatggaag taaggaagaa aaactccgtg aagtggtaga agctccgaca
     6601 gaccgcatcg tcttggttgg aaccaaacca gtagctcaag aagctaaaaa accacaagtg
     6661 tcagaaaaag cagatacaaa accaattgat tcaagtgaag ctagtcaaac taataaagcc
     6721 cagttaccaa atacaggtag tgcggcaagc caagcagcag tagcagcagg tttagctctt
     6781 ctaggtttga gtgcaggatt agtagttact aaaggtaaaa aagaagacta gaaattttga
     6841 taccttcttt atcattaaag accaaagaaa aactcttgtc ctaaatagaa gataaagagt
     6901 ctggaacaaa atagttctca accacaaaaa agctagatat ttccaattgc ggaactctag
     6961 ctttttaatt ttgagtcgtt ctcttattgt atagtagatt gaaactagag tagtacactt
     7021 ctacttctaa aacattgtta gaaatcgatt tgactgtcct tatcgatttg tcctgttctt
     7081 atttcatttc attatgtttt aggaggttat tggccataag taccaatccc atgtcaattc
     7141 tcacttgacg cttgcctctc agattacatc tcttgtaacc caaacaagcc tttatctgcc
     7201 caaagacagg ttccacatca atcttgcgtt gagcgaaaat ctgtctatct tggggagata
     7261 aaagcgcctg acattcttta gctttcaagt tttgatagcg ttcgttcata tacagtccct
     7321 tttgaggggc tgattcaggt tcatcagcgt agtaaacctt gatttcctgt tgaaagtctg
     7381 tctgtgtttt ctggtacttg atatggtgaa aacgatagca ccagccatca ggatgtatgt
     7441 agctatcctc cttgtcatta tagtgccaat tcgctaagtt tttagctgac tgtttatacc
     7501 ctctcttttg tttcttatca aacatggcat atttaatcag aaggggagtg atttcttctt
     7561 gaaaatagac ttgtatctgt tcttgaagtt tggcggagaa tttctctgtc gttttcttcc
     7621 acacaaaact atacttgttg gcattggctt caatcttagt tccgtcaata aacaaacaat
     7681 ctaaggtcac taactcttcc atttttcaat ttttcgacca gagaaaatcc cttgtgaata
     7741 ggcaaataga agagtagata caagcatttt aaggtgataa gacgggcgat caaaggcatg
     7801 atagaaggcg tggaaatgac aatcctccaa ggtattcacc actttttcaa tagtaaaaac
     7861 gagatggtct tgtggcaaga aggaactgat ttctagtggt aaagttgttt gatttgtgtt
     7921 atagtgaata tgcatgggat agcctttcta aatggtttat tgtgcaattc tattttacca
     7981 agactatcgc aaccatgcaa aaaagcaacg gcaaatccgt tgcttttttt ggagataaga
     8041 gactattgtc ccagactctt ttctttgtat aaaattgtat agtgttattg tctatactat
     8101 tttgtagaga aagcaaaaat ccctagaaaa tgcttaggga ttcgactatt tcattaagaa
     8161 caattcaaca atcatttcta catacatgat aagggttaat aagaatcctg cacgccagaa
     8221 gaatttgatg aatttaggat agtaaaagct gcgttttttc aaaaggaaga aaaagacgag
     8281 aataatggct aggatcgaga gggttagccc cagtctaggg aggaaattat gggtaaaggt
     8341 tttagctgta atcaggtaat attcaaatac caagaccgga aaagccaaat ccgcaaagtt
     8401 tcgtcctagt ttttttaatc taaaaagttt ggttaggata atgcagacga ctaaggtcag
     8461 tatcaataat aaaatagatg ctaatttcat taaaatcata cccatattgt atcataaaaa
     8521 aaggctaatg gaaacgagaa acagaggaat ttataggaaa gtcaggcttt tgagattgtg
     8581 ggtgattttt gttataatga aagttataaa atcttataat accttgaatg attattatcg
     8641 aaaactcttt ggagaaaaga cttttaaagt ccctattgat gcgggatttg actgtcccaa
     8701 tcgtgatgga actgtggctc atggaggctg tactttttgt acggtttcag gttctggaga
     8761 tactattgta gccccagatg cgcctatccg tgagcaattt tataaggaaa ttgactttat
     8821 gcaccgcaag tggccggatg ttcggaagta tctggtttat tttcaaaatt ttaccaacac
     8881 ccatgaaaag gtggaagtta ttcgagaacg ctatgagcag gctatcaatg agccaggtgt
     8941 agtaggaatc aatatcggaa cacggccaga ctgtttacca gacgaaacta tcgaatattt
     9001 ggctaaatta tctgagcgca tgcatgtgac ggttgaattg ggcttgcaga ccacttatga
     9061 agcaacctct gatctaatta accgcgctca ctcctatgaa ttgtacgtgg aaacggtcaa
     9121 gcgtttgaga aagtatccaa agattgagat tgtttctcat ttgatcaatg gcttgcctgg
     9181 tgaaacccat gagatgatgg ttgaaaatgt ccgtcgctgt gtcacggata acgatattca
     9241 agggattaaa ctgcacttgc ttcacctgat gactaatacg cgaatgcaac gagattacca
     9301 cgagggacgt ttacagttga tgagtcagga cgaatatgtc aaggtcatct gtgaccaact
     9361 ggaaatcatt cccaagcata tcgtcatcca ccgaattacc ggagatgcac ctcgagatat
     9421 gctgcttggg cctatgtgga gcctcaataa atgggaagtg ctaaatgcta ttgaaactga
     9481 aatgcgacgt cgtggaagtg ttcaaggatg caaggttgta aaacaggagt ttgaaaatga
     9541 aaagaccact tgagatggca catgattttt tggctgaggt agtgacaaaa gaggatatcg
     9601 tagtggatgc gactatggga aatggccatg acacgctttt tttagccaaa ctagccaaga
     9661 aagtctatgc ctttgatatt cagaagcaag ccttggaaaa gacccaagag cgtttgcatc
     9721 aggctggctt gacaaatgcc cagttaatct tgcaaggcca tgagacactg gaccagtttg
     9781 tgacaaaagc taaggcaggg atttttaatt tgggctattt gccgtcagct gataagtctg
     9841 tcatcacccg actgcagaca acgattgagg cattagaaaa gctatgtggc ttacttgtca
     9901 aaggtggacg aattgctatt atgatttact atggtcatga aggaggcgac ctcgagagag
     9961 atgctgtctt ggattttgta atccagttga accaacaaga gtacacagct gccatttacc
    10021 gaactttaaa ccaagtcaac aacccgccgt ttttagtgat gattgaaaaa ttagagagat
    10081 acagacatgg ataaacaata cctacacgaa aagctggatg ccatgcgcca gaattttgtt
    10141 gaatcaaccc accacgaacg atcggtgggc gtgctagacc aagcgcatat gagcaaaaaa
    10201 atgcttaaaa tcaagaaaaa attagttgct cttgaaatgg aacggtgcca gagaaaaatt
    10261 gagcacaaag actgttccaa gattgaccaa aaaatcaaag agcagaagga gatatttgaa
    10321 tcctgttgta aaaaagatta aggaggacgt gcgtggaatt actgatttac ctcatcctat
    10381 ttttactggt tttgattgtc tcaagtacaa ccaataagct cctgcccttt ttgcctctcc
    10441 ctttggtgca aattcttttg ggaattgtga ttggtctctt tttacccaat actgactttc
    10501 accttaatac ggagttgttt ttggcactgg ttatcggacc cttgcttttc cgagaggctg
    10561 aagaagcaga tgttacggct attttaaaac actggcgaat cattgtttat ctcatatttc
    10621 cagtgatttt tatctcgacc ctgagtttgg gtggcttggc ccatcttctt tggttcagcc
    10681 ttcccttggc agcttgcttg gctgttggtg cagcccttgg tcctacggac ttggtggcct
    10741 ttgcctctct ttcggagcgt tttagctttc ctaagcgcgt gtccaatatt cttaagggcg
    10801 aaggactctt gaatgatgct tctggtttgg tggcttttca ggtagctttg acagcttgga
    10861 caactggagc tttttctctg gggcaagcta gcagttcgct catcttttca atcctaggcg
    10921 gttttttaat tggattttta acagccatga ccaaccgctt cctccatacc ttcttgctaa
    10981 gtgtgcgcgc aacggatatt gccagtgaac ttttattaga attgagtttg cctctagtga
    11041 ccttctttct ggcagaagaa gtccatgttt cagggattat tgccgtcgta gttgctggaa
    11101 ttttaaaggc aagtcgcttc aagaaaatca cgctcctcga agcccaagtg gatacggtga
    11161 ccgagacggt ctggcataca gtgaccttta tgctcaacgg ttctgtcttt gtgattttag
    11221 ggatggagct ggaaatgata gcagaaccta tcttgaccaa tccaatctat aatcctctac
    11281 ttttattgct atctctcatc gcccttacct ttgtcctctt tgtcattcgt tttattatga
    11341 tctatggcta ttatgcctat agaacccgac gcctcaagaa aaagctaaat aagtatatga
    11401 aggacatgtt tctcttgact ttttcaggtg ttaagggaac ggtgtcgatt gctacgattc
    11461 tcttgatacc aagtaatcta gaacaggagt atcctctctt gcttttcctt gttgcaggtg
    11521 tgacgcttgt cagcttttta acaggtctct tggtcttgcc tcatctttct gatgaagagg
    11581 aagaaagcaa ggattatctc atgcatatcg ccattttgaa tgaagtaacg ctagagttgg
    11641 aaaaagagtt ggaagacacc agaaataaac ttcccctcta tgcggctatt gacaattatc
    11701 atggacgtat tgaaaatctc attttaagcc aagaaaacca ggatgatcaa gaagattggg
    11761 ctgctttgaa actcttgatt cttagtattg aaagtgatgg tttggagcag gcctatgaag
    11821 aggggaacat tagcaatcgt gcttaccgag tttaccaacg ttatctgaaa aatatagaac
    11881 aaggaatcaa tcgtaaactt gcctcaagac tgacctatta tttccttgtt tctttgcgga
    11941 ttttacgttt tctccttcat gaagttttta ctctcggaaa gaccttccgt agctggaaga
    12001 acaaggagca aagccgtctc cgtgctcttg attatgacca aattgcagag ctctatcttg
    12061 ccaatacaga gatgattatt gaaagtttgg aaaacctgaa gggagtctac agacgctctt
    12121 tgattagttt tatgcaggag tctcgtcttc gagaaacagc tattatcagc agtggtgcct
    12181 ttgtcgaacg ggttatcaat cgtgtcaaac ccaacaatat cgatgaaatg ctgagaggct
    12241 attatctgga gcgcaagttg attttcgaat acgaagaaaa acgattgatt acgactaagt
    12301 atgccaagaa attacgacaa aatgtaaata acttagagaa ctattccttg aaggaagctg
    12361 ccaataccct accgtatgat atggtggaat tggtaagaag aaattagtta atactcttcg
    12421 aaaatctctt caaaccacgt cagcgtcgcc ttaccgtatg tatgtgactg acttcgtcag
    12481 tcttatctac aacctcaaaa cagtgttttg agcagcttgc ggctagcttt ctagtttgct
    12541 ctttgatttt cattgagtat aagattataa gtgaaggagt atgacatgaa aaagtggtgg
    12601 aaagagctga tagacaaacc tttattaaaa gcttttttgc attattatca agcatcagat
    12661 agtgagttga ccagtgtcgc agtagcctac tattggttga tttcgatttt ccccctgctt
    12721 ttggtggtgg tcaatatcct cccctatttt cagattcctg tgggagaatt tttgggcttt
    12781 atgaaagacg tcctgccccc aagcctctat gaaggtgtgg aaaaaatagc cagagaagtc
    12841 ttgacgcaac cttcaacagg tttattgagt ttttctgttt tatcggcgtt atggagtttt
    12901 tcaaaatcta tgaatttctt gcaaaaagct tttaacaagg cttatggcgt cgaaaagagt
    12961 cgtggactta tttcccatca gatgctaagt ctcctagtca gttttggctt gcagctcctc
    13021 tttgcgtttg ccttgttttt gatcttattt ggtcagatga ttttggcttt acttgctcat
    13081 tattggacaa aagatggcat tatctatcag gctttacaag ggttggcagg tcctctgatt
    13141 tacgccctcc tctttgctat cttggtcatg ctttattatt ttcttcccaa tctatctaac
    13201 aggaaaatta gctataccct accaggcagt gcctttgttc tcttagtgat tttaggttta
    13261 ctaactctgt tctctagtta tctcaattac tatgtccatc atttggtgga tgtccgaatt
    13321 ttaggttccg ttcttcttgt tgttatgatg ttttggttta tcttgattgc taaaattgtt
    13381 atcctaggcg cggtgatcaa tgccagtatg cagagtttga aagatccggt ctttaaaaaa
    13441 gactaactat ttatccatta caaaagcgca tagtatcaag gctttataga atcttgatac
    13501 tatgcgcttt tgtgctttga cagttttttg tatagttttt gtccaagatt tctaaatcat
    13561 ctgattaaat tcctattttc ccctatcatt gtccctgttt tttcgaaaat ggaaggagta
    13621 taataaatct atcaataaaa tgataggagg aactttatgg gtcatatttt cttttttcta
    13681 agtgtctttt tggcagggat tctatccttc ttttctcctt gtatcttacc tttgttaccg
    13741 gtctatacag gagtgttact agatgataag gatggtgctc aggcttctag cggcaaattt
    13801 tcaatctcag ttactagttt attacgaact ctggccttta tagcaggaat ttcctttata
    13861 tttattttgt tgggctatgg agctggtttt ttaggcgatt tgctttatgc ttcttggttc
    13921 caatatctta ctggggcaat tattatcctt cttggtttgc accaaatgga gattctacac
    13981 tttaaggggc tttataagga aaagaggcta caactgcaag gacaggggca aaatggtaag
    14041 ggctatagtc aggcattttt attgggcttg acctttagtt ttgcttggac gccttgcgtg
    14101 gggccggttc tggggtctgt tttggccttg gcggcttcag gtggttcagg agcttggcag
    14161 ggagctggtc tcatgttggt gtatacgctg ggcttggcgc taccattctt gcttctagct
    14221 ctgacctcta gttatgtttt gaaacatttc cgaaaacttc atccctatct cggaatcctc
    14281 aaaaaagtgg gtggttttct cattattgtg atgggcttct tggttctgtt tggaaatgct
    14341 tcaattttaa gtcaattatt tgaataaaat ggaaaggaat atcaatatga aaaaatggca
    14401 aacatgtgtt cttggagcag gttcgctcct ttgtttgacg gcttgttcag gcaagtccgt
    14461 gactagtgaa caccaaacga aagatgaaat gaagacggag cagacagcta gtaaaacaag
    14521 cgcagctaaa gggaaagagg tggctgattt tgaattgatg ggagtagatg gcaagaccta
    14581 ccgtttatct gattacaagg gcaagaaagt ctatctcaaa ttctgggctt cttggtgttc
    14641 catctgtctg gctagtcttc cagatacgga tgagattgct aaagaagctg gtgatgacta
    14701 tgtggtcttg acagtagtgt caccaggaca taagggagag caatctgaag cggactttaa
    14761 gaattggtat aagggattgg attataaaaa tctcccagtc ctagttgacc catcaggcaa
    14821 acttttggaa acttatggtg tccgttctta cccaacccaa gcctttatag acaaagaagg
    14881 caagctggtc aaaacacatc caggattcat ggaaaaagat gcaattttgc aaactttgaa
    14941 ggaattagcc taggaggcgt cttatgaatg ataagttaaa aatcttcttg ttgctaggag
    15001 tattttttct agccataacc ggtttctatg ttctattgat acgaaatgca gggcagacag
    15061 atgcctcgca aattgaaaag gcggcagtta gccaaggagg aaaagcagtg aaaaaaacag
    15121 aaattagtaa agacgcagac ttgcacgaaa tttatctagc tggaggttgt ttctggggag
    15181 tggaggaata tttctcacgt gttcccgggg tgacggatgc cgtttcaggc tatgcaaatg
    15241 gtagaggaga aacaaccaag tacgaattga ttaaccaaac aggtcatgca gaaaccgtcc
    15301 atgtcaccta tgatgccaag caaatttctc tcaaggaaat cctgcttcac tatttccgca
    15361 ttatcaatcc aaccagcaaa aataaacaag gaaatgatgt ggggacccag taccgtactg
    15421 gtgtttatta cacagatgac aaggatttgg aagtgattaa ccaagtcttt gatgaggtgg
    15481 ctaagaaata cgatcaacct ctagcagttg aaaaggaaaa cttgaagaat tttgtggtgg
    15541 ctgaggatta ccatcaagac tatctcaaga aaaatccaaa tggctactgc catatcaatg
    15601 ttaatcaggc ggcctatcct gtcattgatg ccagcaaata tccaaaacca agtgatgagg
    15661 aattgaaaaa gaccctgtca cctgaggagt atgcagttac ccaggaaaat caaacagaac
    15721 gagctttctc aaaccgttac tgggataaat ttgaatccgg tatctatgtg gatatagcaa
    15781 ctggggaacc tctcttttca tcaaaagaca aatttgagtc tggttgtggc tggcctagtt
    15841 ttacccaacc catcagtcca gatgttgtca cctacaagga agataagtcc tacaatatga
    15901 cgcgtatgga agtgcggagc cgagtaggag attctcacct tgggcatgtc tttacggatg
    15961 gtccacagga caagggcggc ttacgttact gtatcaatag cctctctatc cgctttattc
    16021 ccaaagacca aatggaagaa aaaggctacg cttatttact agattatgtt gattaatact
    16081 cttcgaaaat ctcttcaaac cacgtcagcg tcgccttacc gtatgtaggg ttactgactt
    16141 cgtcagtttt atctacaacc tcaaagctat actttgagct gacttcgtca gttttattta
    16201 caacctcaaa gcggtacttt gagaaacctg tggctatctt cctagtttac tttttgattt
    16261 ttattgagta taagaggtct ttcctaagca gttagaggag aattttgcta tactgatact
    16321 agtaagtggt aaaggagcag agcatgacct acacaatctt aatcgtagaa gatgaatatc
    16381 tggtaagaca aggtttgact aaactggtca atgtagcagc ctacgatatg gaaatcatcg
    16441 gtcaggctga aaatggaagg caggcttggg aattgatcca aaagcaggtg ccagatatca
    16501 ttttaaccga tatcaacatg cctcatctaa atggcatcca gttggccagt ctggtacgag
    16561 aaacctatcc tcaggttcat ttggtctttt taacaggtta cgatgatttt gattatgcct
    16621 tgtctgctgt caaactaggt gtggacgact acctgctcaa acccttttct cgtcaggata
    16681 ttgaggaaat gttggggaaa atcaaacaaa aactagacaa ggaagagaaa gaagagcagt
    16741 tacaagattt attgactaat aggtttgaag gaaacatggc ccagaaaatc cagtctcatc
    16801 tggctgatag ccaatttagt ttaaagtctt tagccagtga cttaggtttt agtccgacct
    16861 atctgagttc cttgattaag aaagagttgg gcttgccttt tcaggattat ctggtgagag
    16921 aacgtgttaa acaagccaag ctcttgcttt taactacaga tctgaagatt tatgagatcg
    16981 cagagaaggt tggttttgaa gatatgaact attttaccca acgttttaag cagattgcag
    17041 gtgtgacacc tcgtcagttt aagaagggag aagaccgatg aagcgttctt ctcttttagt
    17101 tagaatggtt atttccatct ttctggtctt tctcattctc ctagctctgg ttggaacttt
    17161 ctactatcaa tcaagttctt cagccattga ggccaccatt gagggcaaca gccaaacgac
    17221 catcagccag actagccact ttattcagtc ttatatcaaa aaactagaaa ccacctcgac
    17281 tggtttgacc cagcagacgg atgttctggc ctatgctgag aatcccagtc aagacaaggt
    17341 cgagggaatc cgagatttgt ttttgaccat cttgaagtca gataaggact tgaaaactgt
    17401 tgtgctggtg accaaatctg gtcaggtcat ttctacagat gacagtgtgc agatgaaaac
    17461 ttcctctgat atgatggctg aggattggta ccaaaaggcc attcatcagg gagctatgcc
    17521 tgttttgact ccagctcgta aatcagatag tcagtgggtc atttctgtca ctcaagaact
    17581 tgttgatgca aagggagcca atcttggtgt gcttcgtttg gatatttctt atgaaactct
    17641 ggaagcctat ctcaatcaac tccagttggg gcagcagggc tttgccttca ttatcaatga
    17701 aaaccatgaa tttgtctacc atcctcaaca cacagtttat agttcgtcta gcaaaatgga
    17761 ggctatgaaa ccctacatcg atacaggtca gggttatact cctggtcaca aatcctacgt
    17821 cagtcaagag aagattgcag gaactgattg gacggtgctt ggcgtgtcat cattggaaaa
    17881 gttagaccag gttcggagtc agctcttgtg gaccttgctt ggggccagtg tcacatctct
    17941 tcttgtctgt ctctgcttag tgtggttcag tcttaaacgc tggattgctc ctttgaagga
    18001 tttgagagaa accatgttgg aaattgcttc tggtgctcaa aatcttcgtg ccaaggaagt
    18061 tggtgcctat gaactgagag aagtaactcg ccaatttaat gctatgttgg atcagattga
    18121 tcagttgatg gtagctattc gtagccagga agaaacgacc cgtcagtacc aacttcaagc
    18181 cctttcgagc cagattaatc cacatttcct ctataacact ttggacacca tcatctggat
    18241 ggctgaattt catgatagtc agcgagtggt gcaggtgacc aagtccttgg caacctattt
    18301 ccgcttggcg ctcaatcaag gcaaggactt gatttgtctc tctgacgaaa tcaatcatgt
    18361 ccgccagtat ctctttatcc agaaacaacg ctatggagat aagctggaat acgaaattaa
    18421 tgaaaatgtt gcctttgata atttagtctt acccaagctg gtcctacaac cccttgtaga
    18481 aaatgctctt taccatggca ttaaggaaaa ggaaggtcag ggccatatta aactttctgt
    18541 ccagaaacag gattcgggat tggtcatccg tattgaggat gatggcgttg gcttccaaga
    18601 tgctggtgat agtagtcaaa gtcaactcaa acgtggggga gttggtcttc aaaatgtcga
    18661 tcaacggctc aaacttcatt ttggagccaa ttaccatatg aagattgatt ctagacccca
    18721 aaaagggacg aaagttgaaa tatatataaa tagaatagaa actagctaac tcccagtcaa
    18781 ttctgggagt tttatgcgta attgggcaaa ctttctaggt tgtctatctt gctaaaaaca
    18841 agaaaaaacg gtatgataga agagtgacaa cagaggtaac agagatgaac gagacacaga
    18901 ttcaaagaga aacacgtcag gtagtggaag atgttttaga aaagaccaat ttgaagcagg
    18961 gggccctttt tgttttaggt ctatcttcta gtgaggtgct aggtggtcat attgggaaag
    19021 aatccagtca agagattggt gagctgatag tggagactat cttggatatt ctaggtagta
    19081 gaggtatcca tttagcagtt caaggttgtg agcatgtcaa tcgggctctc gttgttgaac
    19141 gtcaggtggc agagcagttt ggtctggaaa ttgtcagtgt ccatcctact cttcatgcag
    19201 gaggttcggg gcagttggca gcctttaagt ttatgcagga tccagttgag gttgaattta
    19261 tcaaggctca tgctggattg gatatcggag acactgcaat tggcatgcat gtcaagcatg
    19321 ttcaggttcc gattcgccct attttgagag agattggtca tgcccatgta acggcactgg
    19381 ctagtcgtcc aaaattaatc ggaggtgcgc gtgcgcacta tccgcaagat gctattagga
    19441 agttttgaga atgaataaag gagataaaag tgtttaaaaa agaccgtttt tcaattcgta
    19501 agattaaggg agttgtaggc tctgtatttc ttggaagcct tttgatggct ccttctgtag
    19561 tggacgcagc cacctatcac tatgtaaata aagagattat ttcacaagaa gctaaagatt
    19621 taattcagac aggaaagcct gacaggaatg aagttgtata tggtttggtg tatcaaaaag
    19681 atcagttgcc tcaaacaggg acagaagcat ctgttttgac agcttttggt ttgctgactg
    19741 ttgggagctt gcttttaatc tacaagagaa agaaaattgc tagcgtcttt ctagttggag
    19801 ctatgggatt ggtagttctt cctagtgcag gggctgtaga cccagttgcg accctagcgc
    19861 tggctagtcg agagggtgtt gttgaaatgg agggctatcg ctatgttggt tatctatcag
    19921 gtgacatcct caaaacgctt ggcttggaca ctgttttaga agaaacctca gcaaaacctg
    19981 gagaggtgac tgtggtcgaa gttgagactc ctcaatcaat aacaaatcag gagcaagcta
    20041 ggacagaaaa ccaagtagta gagacagagg aagctccaaa agaagaagca cctaaaacag
    20101 aagaaagtcc aaaggaagaa ccaaaatcgg aggtaaaacc tactgacgac acccttccta
    20161 aagtagaaga ggggaaagaa gattcagcag aaccagctcc agttgaagaa gtaggtggag
    20221 aagttgagtc aaaaccagag gaaaaagtag cagttaagcc agaaagtcaa ccatcagaca
    20281 aaccagctga ggaatcaaaa gttgaacaag caggtgaacc agtcgcgcca agagaagacg
    20341 aaaaggcacc agttgagcca gaaaagcaac cagaagctcc tgaagaagag aaggctgtag
    20401 aggaaacacc gaaacaagaa gagtcaactc cagataccaa ggctgaagaa actgtagaac
    20461 caaaagagga gactaaaaca gctaagggga cgcaagaaga aggcaaagaa ggtcaagcac
    20521 cagtacaaga agtaaaccca gaatataaag taacaacagg tacagttgag aagtctaccg
    20581 aaagtgaatt agatttcaca acagaagtag ttccggatga cacaaaatat gtagatgaag
    20641 aagttgttga acgtcaaggg tctaaaggag ttcaagttac gaaaacaact tacgaaacag
    20701 tggaagttgt agagacagac aaagtccttt ctacaactac agaagtgaaa actcctgttg
    20761 ttcctaaagt cgttaaaaaa ggaacaaaac cagttgaagg aacagcagtt gaaacaagag
    20821 aagaagtcat tccttttgct acaaaagaac aagaagatgg cactttaaaa cgcggaacaa
    20881 gacaagtagc tcaagaaggt gtaaacggta agaaacaaat tactgaaacc tataaaacaa
    20941 ttcgcgcaga aaaaacaaac gaagctccaa cagtagaaga aacagttctc caagcacctc
    21001 aagatgagat tatcaaaaaa ggcacaaaag gtttagaaaa accaacctta gaatgggtta
    21061 aaacagataa agatgtcttg aagaagagtg cgacagccag ttatacattg aataaaccag
    21121 atggggtaga aatcaaatcc atcaaagtag ctctaaaaga taatactgga acagttatta
    21181 aagaagtaac ggtagaagaa aataacttaa acgttacttt agacaacttg aaatattatc
    21241 aaggttatac actatccaca accatggtct ataatcgagg cgaaggcgaa gaaactgaaa
    21301 cgttagaaga taaagaagtt cagttagacc ttaaaaaagt tgaaatcaaa aacatcaaag
    21361 aaactagctt gatgagtgtg gatgatgctg gtgttgaaac agataagagc ttacttactg
    21421 aaaaaccgac agacgttgct ccactttacc tacgagtgac aactcatgat aacaaagtaa
    21481 caagacttgc tgttgataag attgaagaag tagaagaaga cggaaaaact ttatacaaag
    21541 ttactgccaa agcaccagac ttagttcaac gtaatgctga taacacactt agcgaagagt
    21601 atgttcatta ctttgaaaaa caacttccaa aaattggaaa tgtgtattac aacttcaacg
    21661 agttgattac agatatgcaa aaaacaccga atggcgagtt taaacttggt gcagacttga
    21721 atgctgtcaa tgttccaaca ccaaataaat cttatgtgac tgctaaattt actggtaagt
    21781 tgtatagtga aggtgataaa cactatacta ttcacaactt agcacgtcca ttgtttgcgc
    21841 aagctgaaaa cgctcatatt catgacatca acctcggtaa tgtaaatatt aatatgccgt
    21901 gggcgaacaa aacagcacct cttggtgaaa tgttcaagaa gtcaactatt gaaaacgtca
    21961 aagtaacagg taatgttgtc ggtaacaatg acgttacagg tatggtcaac aaactggacg
    22021 aatctgatat gcgtaacgta gctttcattg gaaatattac aagtgtaggt agcgctggat
    22081 ggtggtctgg tggacttgtc agtgaaagct ggagaagtaa cacagataat tcttatattg
    22141 ataccaccat caaaggtaat aaagctaagg taggtggatt aattgctaag ttaaatcacg
    22201 gtgctgaccc acgagatgtt ggtgcgagag gtcgtttgaa gaactctgtc gcaaaaggta
    22261 ctattgatgt gagagaccca caagaaactg gtggattgct gcattctaac tggtcatggg
    22321 gtcttgcaga aaacaatatt accatgatga aagtgaagaa tggaggagaa attttatatg
    22381 gttctcgtga tgcagaagat gatgattact tcggagcgaa ttgggtgcgt aataataatg
    22441 cgttcgtcaa tggaatcagt gaagggaaac aatcctattc tcgttctagt cgctggaaag
    22501 ggatttctga agatgaagct aaaactcgta ttgccaaaat gggaattaca gctcatgaat
    22561 acgaaattac acaacatttg actgataaat tgaaccgtgc agcatttaaa gaagacacat
    22621 ataaaacaac tcaagattac aaaactgaaa gagaattagc gtatcgtaat attgaaaagc
    22681 ttcaaccatt ctacaataaa gaatggatta tcaaccaagg taacaaatta acagacggtt
    22741 caaacttaat gattaaagag gtattgtccg ttataggtat gaagaacggt cagttcgtga
    22801 ccgatttgtc tgatattgat aagattatga ttcactacgc tgatggtacg aaagaagaaa
    22861 aaactgtcac acgtaaagct gactcaaaag tgcaacaaat tcgtgaatat agtgttgaag
    22921 gtcttggtga tgttgtgtac acaccaaata tggtcgaaaa agatagagcg caattaatta
    22981 ctgatattaa ggcgaaattg gatagcgtcc aattgatttc accagaagtg cgcaatttga
    23041 tggataaacg tggcaaagcg catgaaaaca cggatgaacg tcgtaatggc tacattcgaa
    23101 acctattcct tgaagaaagt ttggatgaag tgaaaggaaa ccttgataag cttgtgaaag
    23161 ctcttgttga aaatgaagac catcaattga atggtgatga agcggcaatg aaagctcttg
    23221 tcaagaaagt tgaagacaac aaagcgaaaa tcatgttagg tcttgcttat ctcaatcgct
    23281 actatggatt caaatatgac gaaaagtcta tgaaggatat tatgatgttc aaaccggact
    23341 tctatggtaa gaatgttagt gtcttggact tcttgattag agttggttca agagaacaca
    23401 atattaaagg taacagaacg ttagaagctt atcgtgaagt aattggtgga acgattggta
    23461 tcggtgagtt aaacggtttc ttaaactata atatgcgttt attcacagaa gaaactgaca
    23521 tcaatacttg gtacaaaaaa gctgtatcgc ataccaacta tattgttgaa aaacaatcct
    23581 caaaccctgc gtttgccaac aagaaatatc gcctttatga aaacttgaac aatggtgaac
    23641 atggtaaata tattttacca cttctcacta cgaagaaagc tcatatgttc ttgatttcaa
    23701 cctataatac attagcgttt agtgcgtttg agaaatatgg taagaataca gaagctgaac
    23761 gtgaagcgtt taagaaagaa atcgatttac gtgctcaaga gcaaattaat tacttagact
    23821 tctggtcaag acttgcagct gataatgtac gtgacagatt gttaaaatct gaaaatatgg
    23881 ttccgtctgc aatttgggat aaccaagaag ttccaggtca tggatgggct gatagaatgg
    23941 gtcataataa gaatggtgac tatgctccgg ttcgtgagtt ctatggacct acaggtaaat
    24001 ggcatggata caatggtacg ggtgcatatg cttatatctt tactaatcca caaaactcag
    24061 aagctgtata ttatatcata tctagtatga tcagtgattt cggtacttct gcattcactc
    24121 atgaaactac acacattaat gaccgtatgg cgtatctagg tggatggcgt caccgtgaag
    24181 gtactgacgt agaagcattt gcccaaggta tgttacaatc accggctgtc tcaagtccga
    24241 acggcgacta cggtgcttta ggtcttaaca tggcttacaa acgtgaaaac gatggtaacc
    24301 aatggtacaa ctatgattca aataaattag atagtcgtgc gaagattgac cattacatga
    24361 agaattacaa cgaagcgctc atgatgcttg accacttaga agctgatgcc gttatcgcga
    24421 agaataacgg agataacaac aagtggttca agaagatgga taagaaatgg cgtgagaacg
    24481 ctaatcgaaa tggattagtg ggacaaccac accaatggga tttacttcgt gacctaaatg
    24541 aagaagagaa taagaagaaa ttgacaagca ttgatgacct tgtagatgga aattatgtaa
    24601 cgaagcataa tatgccgggt aataaacact atcgtgctga agggtttgat acagcgtatc
    24661 aaactgtaaa catgatggct ggtatttacg gtggtaatac tagtaagagt gctgttggtt
    24721 ctatctcgtt caaacataac accttccgta tgtggggtta cttcggttat cttgatggat
    24781 ttgtaggtta tgcatctaac aaatataaag acgcggctaa caaagaaaat aaaggcttac
    24841 ttggcgacga ctttattatc aagaaagtgt ctgacggtaa atttgacagc ctagaagctt
    24901 ggaagaaaga atggtttaaa gaagttaaag ctaaaggtga aaaaggattt gttgctattg
    24961 aaattgatgg taaaacaatc actaactatg ctgaacttcg tgaattgttc gacaaagctg
    25021 ttgaagctga cctgaaagct ggtaactcta accaaacagt tgcccttaaa gaaaaggttt
    25081 ataaacaact cttgcagaaa tcagatggat ttgtaggaaa tctttttaaa gcatagattg
    25141 tattaaatag atgagtaaaa aaggtagatt aagtttttct tgatctgcct ttttatgcta
    25201 tacttaaggt atgcatagaa aaacagtgat tgattttagg actttggggg agagatatac
    25261 ctttacccag cctattaaag agttgaaaac gagaaatgta gaagaagtgg cagatttgct
    25321 ggcacaagtg gaaagctacc aagagcaagg ttattatgtg gtggggtatg tcagctacga
    25381 ggctgcacct gcttttgagg agaaattagc agttcacaag gttcctctac tgggcgagta
    25441 cttgctttac tttactgttc acgatagggt agagacctcc cctattcctc tgacttatga
    25501 ggatattgat ttgccctcaa attggcagga agtgacgtct gcagcagact atgaaaaggc
    25561 cattgcccag atacaccatc acttgaggca gggagacacc tatcaggtca actacaccgt
    25621 ccaactcaag caaaagttaa gtgccaatcc ttttgccatc tacaatcgta tggtggtaga
    25681 gcaggaggcg ggctacaatg cctatgtgga acatgacgag atggcagtga tttccatgag
    25741 cccagagctc ttttttgagc aaaatgatcg cgagttgaca acacgaccaa tgaaggggac
    25801 gactcagcgt ggggtaactg accaagaaga tcttgaacag gccagttggt tggaacagga
    25861 tcccaaaaat cgctctgaaa atatgatgat tgtggacctc ttgcgcaatg atatgaaccg
    25921 tatttctgaa gttgggagcg agcacgtgga gcgtctgtgt caggtagagc agtattcaac
    25981 tgtttggcag atgacttcga ccatcaagag tcagttgcga gaggatgtgg accttgttga
    26041 aatcttccgc tcactctttc cttgtggttc cataacgggt gcaccgaaaa ttgcgacaat
    26101 ggagattatc aaggacttgg agcctcaacc gcgtggagtc tactgtggaa cgattggtct
    26161 cttgcttcca aatggacgac ggatttttaa tgtggccatt cgtaccattc aacttcacaa
    26221 aggtcaagcc atttatggag ttggcggagg gattacttgg gatagcacat gggaatctga
    26281 ataccgagag gttcatcaaa aggcagcagt tctttatcgt aaacaagctc gcttccaact
    26341 gattacgaca ggggaaatca gccagaagaa cctgctgttt gaagatcaac atctggaaag
    26401 actgagaaaa gctagtcgtt attttgcttt tccttttgat gcagaagact tgggacacaa
    26461 gattgaggaa gagtgtcagg attgtgaagc taatcgagat taccgcttgc gaatcagcct
    26521 tagcaaatct ggagagatag aagtcaatcg tcaagtatta acccctctca gtacaagctt
    26581 ttgtcaggcc caagtctgtc ttcaggaagc tgctttgaat caatccttta cctactttaa
    26641 aaccactcac cgaccgcatt tgagcctagg agaacaagag aagatttacc acaataagtc
    26701 aggagaactg cttgaaacct ctataggaaa tttggttctg aaaatcgctg gaaaactcta
    26761 cacaccgcct atccgacttg gaatcttgcc aggaatttac cgtcagcatt tgctagaaac
    26821 aggacaggta gaagagaaag tcttgacctt ggcagattta acccaagcag aagctattta
    26881 cggctgtaat gcagtgagag gcttgtatga actaagcctt gaggagaact agatgaaatt
    26941 gatatttttg catgggttag ggcagtcagc agagtcttgg aaagaagttc ggaatctact
    27001 gacagattat ccttctgagg ctatcgagtt atttccttct ggagttagta actatcaaca
    27061 agctaaagag cgagtttatc agcacctagc tcaagagaca gaaccttttg ttttgattgg
    27121 attgtcctta ggtgctgccc tgacactaga actttccagt tacgatttac caaatcttcg
    27181 agctttgatt ctgtcaggat gcccgcttaa attagcaggg aatatcctat tttatcttca
    27241 attgctgatt tttaaactac ttcccaaaag agtatttgaa aaacagggag cagacaagac
    27301 tcttatggtc ggagtttctg aggaattgaa gacacttgat ttaacggata tagcagggac
    27361 ttgctcctat ccaaccttac taatttgtgg cagcaaagat aaaccgaatc ttagttctat
    27421 gaaagctctc catagactgt taacagattc gcagtttcag atcattcctg atggccctca
    27481 tgtcttgaat aaggcaaaac caaaggagtt tgtagaaaag accagaagtt tccttgaatt
    27541 gctgaaataa gtttgataaa ataatattga aatcgatatc ataattatgg gagaaagaaa
    27601 tgaataaacg tctattttta aaaatgagtc tggtgacgtt gccaatttta gccttgtttt
    27661 cacaaccagt tttggcggaa gaaaacatcc atttttcgag ctgtaaggaa gcttgggcga
    27721 atggctattc ggatattcac gagggggaac ctggttattc tgccaagtta gaccgtgatc
    27781 atgatggtgt ggcttgcgaa ttgaaaaatg ctcctaaggg tgcttttaaa gcaaaacagt
    27841 caacggctat tcaaatcaac acaagttcag caacaacaag tggttgggtt aagcaggacg
    27901 gcgcttggta ctactttgat ggaaatggaa atctagtgaa aaatgcatgg cagggaagct
    27961 attacctgaa agctgatggt aaaatggcac agagtgaatg gatttatgac tcttcttatc
    28021 aagcttggta ttatttgaaa tcagatggtt cttatgcaaa aaatgcatgg caaggagctt
    28081 attaccttaa atcaaacggt aaaatggcac aaggtgagtg ggtttatgat tcttcttacc
    28141 aagcatggta ttacttgaaa tcagatggtt catatgctcg caatgcatgg caaggaaact
    28201 actatttgaa atcagatggt aaaatggcta aaggtgaatg ggtttatgat gccacctatc
    28261 aagcttggta ttatttgaca tcagatggtt cttatgctta cagtacatgg caaggaaatt
    28321 actatctaaa atcggatggt aaaatggctg tcaatgaatg ggttgatggt ggacgttatt
    28381 atgttggcgc tgacggagtt tggaaggaag gtcaagcaag tacagcttct tctagtaatg
    28441 atagcaatag tgaatattct gctgctttag gaaaggcaaa aagttataat tcgttattcc
    28501 acatgtcaaa aaaaacgtat gtatagacaa ttaacttctg attttgataa attttcaaat
    28561 gatgcagctc aatatgccat tgatcattag atgattaaca gatactggta ggcgaaaaaa
    28621 ttccttataa ttcacttacg caaacctttg cataagtgaa tggattttga tatactagta
    28681 ctgtaagcat tttcaattac tacacaatga aaaaggagaa tatgatgagt caaaagatta
    28741 ttgggattga ccttggtgga acttctatca aatttgcaat cttaacaaca gcaggagaaa
    28801 tccaaggaaa atggtcaatc aagaccaaca ttttggatga gggaagtcat atcgttgatg
    28861 atatgattga gtctattcaa catcgtttgg acttgcttgg attggcagca gcggacttcc
    28921 aaggcattgg aatgggatca ccaggtgtgg ttgaccgtga caaagggact gttatcggtg
    28981 cctacaactt gaactggaaa acccttcaac caatcaaaca aaagattgaa aaagccttgg
    29041 gcattccatt tttcatcgat aatgatgcca acgtagcagc tcttggtgag cgctggatgg
    29101 gtgctggaga taaccaacca gacgttgtct ttatgacact cggtactggt gttggtggtg
    29161 gtattgtcgc agaaggcaaa ttgcttcatg gtgttgctgg tgcagcaggt gaacttggtc
    29221 atatcactgt tgattttgac caaccaattg catgtacttg tggtaaaaaa ggctgccttg
    29281 agacagttgc ttcagcaaca ggaattgtca acttgactcg tcgctatgcc gatgaatacg
    29341 aaggcgatgc agccttgaaa cgcttgattg ataacggaga agaagtaact gctaagactg
    29401 tctttgatct cgcaaaagaa ggagacgacc ttgctttgat tgtttaccgt aacttctcac
    29461 gttacttggg aatcgcttgt gctaacattg gttcaatcct aaacccatca acaatcgtca
    29521 tcggtggtgg tgtgtcagct gcgggagaat tccttctaca aggtgttcaa aaagtctatg
    29581 atgaaaatac tttcccacaa gtacgcacat ctactaaatt agctcttgca actctaggaa
    29641 atgacgctgg agttatcgga gcagcatcac ttgtattgca ataagataat gagagaggaa
    29701 aaatgctaac ctagagttag taatgttcct cttttatttt ttatgctata ctagttagga
    29761 caatgaatga ggtgagagta aatgacaaaa gcagatacga tttttaaaga gaatattgaa
    29821 cgcattctaa aggaaggtgt tttctcagag caggctcgtc ctaagtacaa ggatgggact
    29881 gttgctaatt ccaagtatgt aactggtgcc ttttccgagt acgacttatc taaaggagaa
    29941 tttcctatca caaccttgcg tcccattgca atcaaatccg ccatcaaaga agttctctgg
    30001 atttaccaag accagtcaaa tagcttagaa gtgcttaatg acaagtacaa tgttcactac
    30061 tggaatgact gggaagttgg agacacggga accattggtg agcgctatgg tgccgttgtt
    30121 aagaaacacg acattatcaa taagcttctc aaacagttgg aaaccaatcc ttggaatcgc
    30181 cgcaatatta tttcgctctg ggattaccaa gctttcgaag aaacagatgg gctgctcccg
    30241 tgcgcctttc agaccatgtt tgatgtccgg cgtgttgatg gggaaatcta tctggatgcg
    30301 accttgaccc agcgctccaa tgatatgctg gtggcccacc acatcaacgc tatgcagtat
    30361 gtggctttac agatgatgat tgccaaacat tttggttgga aggttgggaa gttcttctat
    30421 ttcatcaaca acctccatat ctatgataat caatttgaac aagctcagga attgctccgt
    30481 cgggagccgt caaactgcca accacgcttg gttttaaatg ttcctgatgg gactaatttc
    30541 tttgatatca aagcagaaga ttttgagttg gtggattatg accctgttaa gccacagttg
    30601 aagtttgacc tagctattta aaagaataga aaaaagaagt tgagaataat cccaacttct
    30661 tttgtttctt aacgtgatac gcggcgacga gctgcttttt tacgattttc ttcgatgaaa
    30721 gctgcttttt gctcttctgg ttcgattact ttctttttaa atgcgtatac tgcacctgca
    30781 acggcagcga cagttcctgc gacacctgtt acaagacctt tagcgaatcc tttagccatg
    30841 agtcttcctc ctttatattc tcaatcagcc agcctcctca agaggtcaca tttttctgac
    30901 tgaccttttt gtgttataat aatagtaacg aaaaaatggg aatttttcaa ggaaaaaaga
    30961 tgaaaacaaa aataattgtg attgttggac cgactgctgt tggaaagacg gctctagcta
    31021 ttgaagttgc aaagcgcttt aatggcgaag tggttagtgg agatagccag caagtctatc
    31081 gaggacttga tattgggacg gccaaggcta gtccagaaga gcaggcagct gttcctcatc
    31141 atttaatcga tgttagagag ataaccgagt cttactcggc ttttgatttt gtttcagaag
    31201 ctaagatgac tattgaggat attcagagcc gtggcaagct agccattatc gccggtggga
    31261 ctggacttta tatccagagc ttgctagaag gttaccacct aggtggggag actccttatg
    31321 aggagatttt agcttatcga gctagtttgg agccatattc agatgaggaa ttagcccatt
    31381 tggtggagca agcaggcctt gagattcccc agtttaatcg tcgtcgtgct atgcgtgcct
    31441 tagaaattgc ccattttggt caggatttgg aaaatcaaga gatcttgtat gaaccgctga
    31501 ttatctgctt ggatgatgaa cgtagtcaac tttatgagcg tatcaaccac cgagtggatt
    31561 tgatgtttga ggctgggctt ttggatgagg ccaagtggct gtttgaccat tcccctaatg
    31621 tacaggctgc taaaggaatt ggctataagg aactctttcc ttatttccgt ggagagcaga
    31681 cctttgagga agctcgtgag agtcttaaac aggcgacccg tcgttttgcc aagcgtcagc
    31741 tgacctggtt ccgtaatcgc atgcaggtca ccttttatca gattggagaa tctggtgtac
    31801 aagaccgcat tttaagccag atagaggagt ttttagatga ttgaaacgga gaaaaaagag
    31861 gagcgagtcc tgctgattgg tgtggaattg cagggtatgg acagttttga cctctccatg
    31921 gaagaattgg ctagtttagc gaaaacggca ggggcagtcg ttgtagatag ctacagacaa
    31981 aaacgtgaaa aatatgattc caagaccttc gtcggctctg gtaagttgga agagattgcg
    32041 cttatggtgg atgcagaaga aatcactact gtcatcgtca acaaccgtct gaccccaagg
    32101 cagaatgtca atctagagga agttctcggt gttaaggtca ttgaccgtat gcagttgatt
    32161 ttggatatct ttgccatgcg ggctcgaagc catgaaggga agctccaagt ccacctagcc
    32221 caactcaaat acctcttgcc tcgcttggtt ggtcagggga ttatgctcag ccgtcaggca
    32281 gggggaattg gttcccgtgg tcctggtgaa agccagctgg agctgaaccg tcgtagcgtt
    32341 cgcaatcaaa tcacggatat cgagcgccag ctcaaggtgg ttgagaaaaa tcgggcgact
    32401 gtcagagaaa aacgtttgga gtctagcacc tttaagattg gtttgattgg ttataccaat
    32461 gctgggaaat caactatcat gaacatcttg accagtaaga cccagtatga agcagatgag
    32521 ctctttgcga ctctggatgc gacaaccaag agtattcatc tgggaggcaa tctccaagta
    32581 actttgacag ataccgttgg ctttattcaa gatttgccga cagagttggt gtccagtttc
    32641 aagtcaacct tggaagaaag caagcatgtg gaccttctgg ttcatgttat cgatgctagc
    32701 aatccttacc acgaggagca tgaaaaaacg gttctctcca tcatgaaaga cctggacatg
    32761 gaagatattc ctcacttgac gctttataat aaagcggatt tggtggagga tttcacgcct
    32821 acccaaacgc catataccct catttctgcc aagtctgagg acagtcgtga aaacttgcaa
    32881 gcattattgc tagataagat taaggaaatt tttgaagcat ttaccctgcg agtgcctttt
    32941 tcaaagtcct acaagattca tgatttagag agtgttgcaa ttctggaaga acgtgattat
    33001 caggaagacg gcgaagtgat tacaggctac atttccgaga aaaataaatg gaggttagaa
    33061 gaattttatg actgatatta aaactttggc tctaaagtat ggaggttata caagtctgga
    33121 caaggtctat ctggatcagc ttctagctgg taaaacagag caggagcagt taacacttat
    33181 tacacctccg ccaagtgttg ttaatgccta ctttgcagaa ctctatcaga aaaaaagtcc
    33241 tcaggctgcg acggattatt ttgcagaact cagtcaggaa ctgaatcttt acaatactga
    33301 gccaagtttc accctagaaa ataagccttt tattcggctt aatctgtctg gtaaatcctt
    33361 tggtttttgt tatgagagtg acggctttgg tcggattttc tctgaaaatg aggagaaaat
    33421 ctcggatgac ttgctctttg aaattgcgca aattttctcc catcaattag tctttgaaga
    33481 gtctggtaag atttacatga agcctgtcaa ggacgaggaa gttgtcagcc tagaaagtct
    33541 cacagctttg actgatttgg aaagattggc tgatggtcga aaacgtctca aaggctacag
    33601 ccaagaggat ttattgcaag aagctgctgc tttttctggc aaacgctatt tccgatcgga
    33661 aaaccgcaca gccatgttat atattgatta attagaaagt atcgaatgga tattcaattt
    33721 ttaggaacgg gggctggtca gccctctaaa gcccgcaacg tttcaagtct cgccctgaaa
    33781 cttttggacg agattaacga agtttggctc tttgactgtg gagaaggtac gcaaaatcgc
    33841 attctggaaa ccacaattcg accacgtaag gtcagcaaaa tctttattac ccatctgcat
    33901 ggagaccaca tttttggttt gccaggtttc ctttctagcc gtgcctttca ggccaatgaa
    33961 gagcagacag atttggaaat ctacggacct caaggaatca agtcatttgt cttaaccagc
    34021 cttcgtgtgt caggttctcg tctgccctac cgcattcatt tccatgagtt tgaccaagat
    34081 tctctgggta aaattcttga aaccgataaa ttcactgtgt atgcagagga gctggaccac
    34141 actattttct gtgttggcta tcgtgtcatg caaaaggatc tagaagggac gctggatgct
    34201 gaaaaactca aggctgctgg tgttccgttc ggcccgcttt ttggtaaaat caaaaacggc
    34261 caggatcttg ttttggaaga cggaactgaa atcaaggcag cagactatat ctcagcgcca
    34321 cgtccaggta agattatcac tattttagga gacactcgaa aaacggatgc cagtgtgcgt
    34381 ctggctgtca atgcagatgt cctagttcat gagtccactt atggcaaggg tgatgaaaaa
    34441 attgctcgta accatggtca ctcaactaat atgcaagctg cacaagtagc ggtagaagca
    34501 ggtgccaaac gcctcctact caaccatatc agtgcccgtt tcctctcaaa agatataagc
    34561 aaactcaaga aggacgctgc cacaattttt gaaaatgtcc atgtggtcaa agacttggaa
    34621 gaagtggaaa tctagcagtc acagaaagga taagtatgcc tactattctc attaccggag
    34681 ctagcggtgg tctagctcaa gaaatggtca aactcctgcc caatgaccaa ctcatcttgc
    34741 ttggtagaaa taaggaaaaa ttagcccaac tctacggaaa ttattcccat gcagaattga
    34801 ttgaaattga tattaccgac gattcagccc tagaagctct ggtaactgat ctttatctcc
    34861 gctatggcaa gattgatgtc ttgattaaca acgctggtta cgggattttt gagggatttg
    34921 accagattgc tgataaagat attcaccaga tgtttgaggt caataccttt gccctgatga
    34981 atctgtctcg tcaccttgcg gctcgtatga aggaaagcag caaagggcat atcatcaaca
    35041 tcgtcagcat ggcaggtcta atagctactg gcaagtctag tctttactca gcgaccaagt
    35101 ttgcggctat tggtttttca aatgctctgc gactcgaact tatgccctat ggagtctatg
    35161 tgacaacagt caatccaggt ccaatccgaa caggattttt tgaccaagct gacccagatg
    35221 gaacttatct taaatcggtt gaccgcttcc tcttagaggc agatgcagtg gctaaaaaga
    35281 ttgtcaagat tataggcaaa aataaacgag aactcaatct cccgattttg ttgaacctag
    35341 cccataagtt ttatactctc tttcccaagc tagctgataa gttggcaggg gaaactttta
    35401 attataagta aaaagaacca atgtgcaggt tgttgctagc ctacatattg gttcttatca
    35461 tttctcaact atcaaactga acttcttcta gtagatagtc gataaagcgt tcgcccatct
    35521 tagataggct ggttttctca tgctggatat agaccagctc aatcgggtca tcaatatcca
    35581 gtgggataga aacgatattg tctccgttta ggttgctgtt caaaatccct gtcgcaatgg
    35641 tataaccatc caaaccaatc aagagattaa agagggtggc acggtcactg accacaatgg
    35701 atttcttgtg gtgttcctga gaaagaatct cttctgaaaa gtagaaggag ttgtgcgtcc
    35761 cttggtcata gctgaggtaa gggaaattct ccaaatcaga cagtttcacc ttgtctttct
    35821 ttgccagagg gttggtcttg ctgacaaaga tatgcggttg cgctgtgaag agatggtggg
    35881 ctagcaggtg attgtcatcc agcatcttgg ttaaaacatc acggttgtaa ctgtttaaga
    35941 agaggacccc gacctcactg cggaagttct tgacgtcgtc gataatctcc caagtccgag
    36001 tttcacgaag gaagagttcg tatttctcca tatcgctttt cttgagcaaa gagacaaagg
    36061 cattgaccac aaaggcatag tgttgagacg aaacgctaaa gagttcgcgg tgggcgacag
    36121 gatttttata gcgttcctcc agaagctggg tctgctcgac aacctgacgg gcataagaga
    36181 gaaactccat cccatcacgg gtcaaggtga ttcccttggg attgcggata aagatctcaa
    36241 tgcccatttc attttccaaa tctcgcactg cattggagag acttggctga gtgataaaga
    36301 gttgcttggc tgcctcattc atggagccag tttcgacgat tttgataata taatgtaatt
    36361 gttgaattct catgttttta ttgtaccata cttgccttag aatcgctaaa gaagatagga
    36421 aaataaggag cattgtatga gtctcttctt gaaaaaaaca caaaattttg ctagaatgag
    36481 tcttatgaaa acattctatg atgtgcagca attcctcaaa cgatttggta ttattgttta
    36541 catgggaaaa cgcttatatg atattgaact gatgaagttg gaactatctc ggatttacga
    36601 tgcagggttg atggataaat tagactatct agaggcagaa gcagttcttc gcagagagca
    36661 caaggtagaa ttggattata ttgagaaaaa tggagaaaag aactaatggt tacttggatt
    36721 ttgtgggcac ttatactagc aatgttggcg tggatgggct ttaactatct tcgtattcgc
    36781 cgtgcggcta aaattgtgga caataaggag tttgaagcct tgattcgtac gggtcaattg
    36841 attgatttgc gcgacccagc agaattccac agaaaacata tccttggtgc acgcaatatt
    36901 ccttcaagtc agttgaaaac tagtcttgca gcacttcgta aagataaacc tgtccttctc
    36961 tacgaaaacc aacgtgcgca acgagttaca aatgcagctc tttacttgaa aaaacaaggt
    37021 ttttctgaga tttatatcct ttcttatggc ttggattctt ggaaagggaa agtgaagact
    37081 agctaacctt atttccaaat tagtcgaatg ataggatgaa gctattgttt tatagtataa
    37141 ttaatttgta taaaatttaa ggagttctta gaacataaaa gaaaagaaga aaaatccact
    37201 ttttgtgggt atcttgtcga ttattcttgg tttgttattt ccaattgtag gcctgatttt
    37261 gggtatcata ggattggtct tggctatttc ataccaaaaa gagtcacaat tagactataa
    37321 aatagaaaag attcttaata tcttaggaat tgtgatttct gtagttaact ggattgtagc
    37381 aatcgcctta atttttcggt aaataaaaga aaaaagcttt agttttaaag ctttttttgt
    37441 tttatcgact catctctaaa tagtttttaa tgatttgtaa ctctttttgg ttcaaagggc
    37501 ggtagttacc ttctgctaaa tctgggttca atgtgaagtc cccaaattgg attcttttga
    37561 ggctagtcac cttaacacca accgagagga acattttctt gatttgatga aattttcctt
    37621 ctgaaatggt gatagaggct tgactgaggg aaggacttgc tgatagaatc tctagtcttg
    37681 caggtttaca gatagtgcca tctaaaaaga caattccttt ttgaaaggtt tggatatggt
    37741 caggtgttag aagtccatta acctcaactt gataagtctt atcgacatga tattggggat
    37801 ggaggagttg gaagcccaag ggaccgttat cggtcaagag aaggagtcct gttgtatctc
    37861 ggtccagtcg gccgacggca tagagcttgt cagactggat gtcagatgga agcaagtcca
    37921 tgacggtcgg aagttccttg tctttgttgg ctgtaacgac accagcaggt ttatgaagca
    37981 taagataggt gtgttcatag ccttgaatga ttcgatcctg aaaaaggagt tcttgtagtc
    38041 ctgtatcgat attttgagct agggagcggg ctgggcaacc atcgactaga atgtcccctt
    38101 tgagtaaggc ttgtttcatg gcctttcggc tgattttttc ttgagctaat aaattatcta
    38161 aacgcatact gtgcctatct tatcataagt cgcttgcttt gaaaaggctt gacgtgaaaa
    38221 gaaaagtgga gtgaaaacat ttacacttgc ttgagttatg ttatttactt gaaattatgg
    38281 tataatcgtt cagttagaaa ataaattttg aatattatag aggaaatcat gacaaaatta
    38341 agagaagata tccgtaacat tgcgattatc gcccacgttg accacggtaa aacaaccctg
    38401 gttgacgaat tattgaaaca atcagaaacg cttgatgcac gtactgaatt ggcagagcgt
    38461 gctatggact caaacgatat cgaaaaagag cgtggaatta ccatccttgc taaaaatact
    38521 gccgttgctt acaacggaac tcgtatcaac attatggaca caccaggaca cgcggacttc
    38581 ggtggagaag ttgagcgtat catgaaaatg gttgacggtg ttgtcttggt cgtagatgcc
    38641 tatgaaggaa ccatgccaca aactcgtttc gtattgaaaa aagccttgga acaagacctt
    38701 gtcccaatcg tggttgttaa caaaatcgat aagccatcag ctcgtccagc agaagtagtg
    38761 gatgaagtct tggaactttt catcgagctt ggtgcagatg acgaccagct tgatttccca
    38821 gtggtttatg cttcagcgat caacggaact tcttcattgt cagatgatcc agctgaccaa
    38881 gaagcgacta tggcaccaat ctttgacacg attatcgacc atatcccagc tccagtagat
    38941 aactcagatg agcctttgca gttccaagtg tcacttttgg actacaatga cttcgttgga
    39001 cgtatcggta tcggtcgtgt cttccgtggt acagttaagg ttggggacca agttaccctt
    39061 tctaaacttg acggtacaac taaaaacttc cgtgttacaa aactcttcgg tttctttggt
    39121 ttggaacgtc gtgaaatcca agaagccaaa gcgggtgact tgattgccgt ttcaggtatg
    39181 gaagacatct ttgtcggtga aaccatcact ccgacagatg cagtagaagc tcttccaatc
    39241 ctacacatcg atgagccaac tcttcaaatg actttcttgg tcaacaactc accatttgct
    39301 ggtaaagaag gtaaatgggt aacttctcgt aaggtggaag aacgcttgca ggcagaattg
    39361 caaacagacg tttcccttcg tgttgaccca actgattcac cagataaatg gactgtttca
    39421 ggacgtggag aattgcactt gtcaatcctt atcgaaacaa tgcgtcgtga gggctatgaa
    39481 cttcaagtat ctcgtccaga agttatcgta aaagaaatcg acggtgttaa atgtgaacca
    39541 tttgaacgtg tacaaatcga cactccagaa gaataccaag ggtctgttat ccaaagcctt
    39601 tctgaacgta aaggtgaaat gttggatatg atttcaactg gtaatggtca aactcgtttg
    39661 gtcttccttg ttccagcgcg tggtttgatt ggatactcaa ctgagttctt gtcaatgact
    39721 cgtggttacg gtatcatgaa ccataccttc gaccagtact tgccattgat tccaggggaa
    39781 attggtggac gtcaccgtgg tgcccttgtt tctatcgatg ctggtaaggc tacaacttac
    39841 tcaatcatgt ctatcgaaga acgtggtacg atctttgtca acccaggtac tgaggtttat
    39901 gaaggaatga tcatcggcga aaactctcgt gaaaatgact tgacagttaa catcacgaag
    39961 gcaaaacaaa tgaccaacgt tcgttcagct actaaggacc aaacagctgt tatcaagacg
    40021 cctcgtatct tgacacttga agagtctctt gagttcttga acgacgatga gtacatggaa
    40081 gtaacgcctg agtctatccg tttgcgtaaa caaatcctta acaaagcaga gcgtgagaaa
    40141 gctaacaaga agaaaaaatc agctgaataa gagctagaaa gagagaaaga tggtctattt
    40201 agtcctagga attttactgc tcctactcta tgtatttgcg acaccagaaa gcattaaagg
    40261 gacagtcaat atcgtcgcta tggtatgtat tttagtggca ctcttgattt tattggttct
    40321 atcttttctg aaaatttttc aattaccaac agaaatattc ctagcaatag ccatgttgat
    40381 cctagcttac tttagtgtga gagacatcac actcatgcca gtcaaaaaaa gtaaaagaag
    40441 ataaaaaaga gagttttggc tctctttttt gctaggaatt ttacaagatt gcaatttatt
    40501 tttgagttat caccatctct tttgtttgga taatatgaat gggaaaaact tgaataaaat
    40561 tctttaatgg aatctatttt atatttgctt agtactggtt gcatattatt tcgaaataaa
    40621 actactatat aatattattc atagagataa tatagtaaaa tatctaaaaa attcgatttt
    40681 ttccttgaca acaaataata aaaatgttat tcttatcaca taagaaagcg gtttcaacaa
    40741 aagagagagg aggatttatt ttgttgcatt gttgctcagg gtgtgctttt tttgaaagaa
    40801 aaaataaaat gaaaacgaaa aaacatagat tacttgctct agctcttatt tcaagtttta
    40861 cattattggg agctgcatca gctgctgtac aatatccaga tggaggagta tggacatatg
    40921 gagaaggttc aggaggtggt tgggcttttt caaattacta tcatggtaaa aaatatcatt
    40981 attcatccat cgtgagcaga tggaatggtc attctgataa aggagaagct cctgctggaa
    41041 aaacctccta tgcatggatt tggactaaat ggggagaaca agtagcattt tactgtgatt
    41101 atgactaatc gttcattgat ttaaatcgtt ccccttgtaa gaaattacag ggggaatttt
    41161 gtttacaagg agtctactat gaagaaacta ttcatattat tatcaacttt ttttctcagc
    41221 ttcttccttg cttggattat tgtcttacgt gcgccacaat atttatatgc aagctatgat
    41281 tccgtttctt tacttcgtgt caaaaaagat actcaggaac cgacgcgtga ggtatttgaa
    41341 caggaattgg agaattttgc aaattcagaa cagagtttaa tagctagaag aattgtagag
    41401 ccgagtaagg atgggacgac tcactttatt tatgcaactt atggtcaggg aactttacca
    41461 aaagaattcc aagaagctag ccaagaaagt cgtgaacgta gtgatccgct aaatagttat
    41521 ctccttttgt caggttcctt gacgaaagaa aagcttgccg ataaattagg agatttgggt
    41581 tataaagcaa gtgctgaccg aaagataccg ccctattttc ttgcttttcg aatattacta
    41641 aatcccctta ttttaattag tttagcaata tttggcttat ctttctttgc tttagtgatt
    41701 atcactcgga ttaaggaaat gagagcagca ggtataaaac tcttttctgg tcagactctc
    41761 ttatccatca tggggcattc tttatctact gatatcaaat ggctccttct atcagccctc
    41821 ctttccttcc taggtggggg agtcgttctt tttagtcaag gtttgtttta tcctatcttg
    41881 ttagccacct atggttttgg gattagtttc tatctgttgt ttttattggc gatttcaatt
    41941 ttactaatgc tcctttatct aatgagtttg aattacaaag cattagttcc cgttattaag
    42001 gggagattac cccttaaacg cctgatgatt ttaaccctat tgtgtcagtt ggttgctgtc
    42061 tttacagtag gatacgctgt taagacaggt ttgacgtctt accaacgatt gaaagaactt
    42121 gaaatttcaa aacaagcatg gcaggataga gcagactatt atcaaatttc ttttggctta
    42181 ggtgatagag gaaaagatat agaaaatcag agcaagtggt atgcctttgc caaggaagca
    42241 atcgaagaag aacaagctct ttatgtaaag gataatctgc tccattttgc caatccacaa
    42301 ggaaaaaatg aacagggaga gacactggat acctatagtc cagatgctaa tacgctctat
    42361 gttcgtccca gttatttgga caaggaaaag gtcgtggtag atgctgagac caaacagaag
    42421 ttagcccatc tccaaaaagg tgagtttatc ctcttgctcc cagaacattt gcgctctcga
    42481 gaagcagaac ttaagaaagt ttttgaagaa agattgagtt attatggaaa atctggtgag
    42541 gaggcaagtg ctcctttgga ttatgagatg aaagcgcacg ttagttatct ttcaatggga
    42601 gaaaagcggt ttgtttataa taacggtgag aatcccgtat ccactcagta tttgactgat
    42661 ccgattttag tggtattcac gccgacttct acaggtgata gttttatatc cttatctagt
    42721 tggtctatca atgctggaaa acaactcttt atcaaaggat atgagagtgg gctagaactc
    42781 ttgaagaaag ctggaattta tgagcaagta tcctatctta aagaaggaag aagtgtttat
    42841 ctaactcgtt ataatgaagt tcaaactgaa acagcaactt taatcttagg agctattgtg
    42901 gggatagcta gttccttgtt actattttat tctgtcaata ttctatattt cgagcaattc
    42961 cgccgagata tcttgattaa acgaatttca ggtttacgat tttttgaaac acatgctcag
    43021 tatatggtta gccaatttgc cagttttgta tttggtgcta gtctctttat tttaagcagt
    43081 cgagacttgg tgattggctt gctcacttta ttggtctttc tagctagtgc agttttgacg
    43141 ctttaccgtc aagcgcagaa agaatctcgt gtttctatga caattatgaa aggaaaatag
    43201 gatgattgaa ctaaagaata tatctaaaaa atttggaagc cgtcagctat tttcagatac
    43261 gaatcttcat tttgaaggtg ggaaaattta tgccttaatc ggtacaagtg gctgtggtaa
    43321 gacaacactc ttgaatatga ttggacgatt ggagccatat gacaaagggc aaatcatcta
    43381 tgatggcact tctcttaagg acatcaagcc ttctgttttc tttagagatt acttgggata
    43441 cttatttcaa gattttggct taattgaaag ccaaaccgtc aaagagaatc tcaatctggg
    43501 tttagttggt aaaaagttga aggaaaaaga gaaaatctct ttgatgaaac aagctctaaa
    43561 ccgtgtaaac ctctcttatt tggatttgaa gcaacctata tttgagttat caggaggaga
    43621 agcacaacgt gttgcactag cgaagataat tttaaaggat ccgcctttga ttcttgcaga
    43681 tgaaccaacc gcttccttag accccaaaaa ctctgaggaa ttactttcca tcctagaatc
    43741 tttaaaaaat ccgaatcgga ccattattat tgcgacccac aatcctctga tttgggagca
    43801 agtggatcag gtcattcgag ttaccgattt atcacataga tgatatggta agattcagtt
    43861 agaagaaaga gtcacaaaca cactttgtgg cttttttatt tccataaaaa tggtaaaata
    43921 gtaggagtag aaatggagtt cgagacatga aagtaataga tcaatttaaa aataagaaag
    43981 ttcttgtttt aggtttggcc aagtctggtg aatctgcggc tcgtttgttg gacaagttag
    44041 gtgccattgt gacagtaaat gatgggaaac cattcgagga caatccagct gcccaatgtt
    44101 tgctggaaga agggatcaag gtcattacag gtggccatcc tttggaactc ttggatgaag
    44161 agtttgccct catggtaaaa aatccaggta tcccctacag caatcccatg attgaaaagg
    44221 ctttggccaa gggaattcca gtcttgactg aggtggaatt ggcttatttg atttcagaag
    44281 caccgattat tggtatcaca ggatcgaacg gtaagacaac cacaacgact atgattgggg
    44341 aagttttgac tgctgctggg caacatggtc ttttatcagg gaatatcggc tatcctgcca
    44401 gtcaggttgc tcaaatagca tcagataagg acacgcttgt tatggaactt tcttctttcc
    44461 aactcatggg tgttcaagaa ttccatccag agattgcggt tattaccaac ctcatgccaa
    44521 ctcatatcga ctaccatggg tcattttcgg aatatgtagc agccaagtgg aatatccaga
    44581 acaagatgac agcagctgat ttccttgtct tgaactttaa tcaagacttg gcaaaagact
    44641 tgacttccaa gacagaagcc actgttatac cattttcaac acttgaaaag gttgatggag
    44701 cttatctgga agatggtcaa ctctacttcc gtggtgaagt agtcatggca gcgaatgaaa
    44761 tcggtgttcc aggtagccac aatgtggaaa atgcccttgc gactattgct gtagccaagc
    44821 ttcgtgatgt ggacaatcaa accatcaagg aaactctttc agccttcggt ggtgtcaaac
    44881 accgtctcca gtttgtggat gacatcaagg gtgttaaatt ctataacgac agtaaatcaa
    44941 ctaatatctt ggctactcaa aaagccttgt caggatttga caacagcaag gtcgtcttga
    45001 ttgcaggtgg tttggaccgt ggcaatgagt ttgacgaatt ggtgccagac attactggac
    45061 tcaagaagat ggtcatcctg ggtcaatctg cagaacgtgt caaacgggca gcagacaagg
    45121 ctggtgtcgc ttatgtggag gcgacagata ttgcagatgc gacccgcaag gcctatgagc
    45181 ttgcgattca aggagatgtg gttcttctta gtcctgccaa tgctagctgg gatatgtatg
    45241 ctaactttga agtacgtggc gacctcttta tcgacacagt agcggagtta aaagaataat
    45301 atgaaaaaaa ttgtctttac aggtgggggg acggttggac acgttaccct caatcttttg
    45361 ttaatgccca agttcatcga agatggttgg gaagtccact atatcgggga caagcgtggt
    45421 atcgaacacc aagaaatcct taagtcaggt ttggatgtca ccttccattc tattgcgact
    45481 ggaaaattgc gtcgctattt ctcttggcaa aatatgctgg acgtcttcaa agttggttgg
    45541 ggaattgtcc aatcgctctt tatcatgttg cgactgcgtc cacagaccct tttttcaaag
    45601 gggggctttg tctcagtacc gcctgttatc gctgcgcgtg tgtcaggagt gcctgtcttt
    45661 attcacgaat ctgacctgtc tatgggcttg gccaataaaa tcgcctataa atttgcgact
    45721 aagatgtatt caacctttga acaagcttcg agtttggcta aggttgagca tgtgggagcg
    45781 gtgaccaagg tttcggacaa aaacactcca gaaccagatg aattggtgga tattcaaacc
    45841 cactttaatc ccaaattgcc aactgtattg tttgttggcg gttctgcagg cgctcgtgtc
    45901 tttaaccaat tggtgacaga ccataagaaa gaactaacag agcgctacaa tattatcaat
    45961 ctaactggag attctagcct gaatgagttg aggcaaaatc tttttcgtgt tgactatgtg
    46021 accgatctct atcaaccctt gatggaattg gctgatattg ttgtgacacg aggtggtgcc
    46081 aatacgattt ttgagctctt ggcgatagca aaattgcatg tcattgtgcc gcttggtcgt
    46141 gaagctagtc gtggtgacca gattgaaaat gcagcttact ttgtaaaaaa aggctatgca
    46201 gaagaccttc aagaaagcga tttgaccttg gatagtttgg aagagaagct ttctcactta
    46261 ctaagtcaca aggaagatta ccaagctaag atgaaagctt ctaaggaatt gaaatctcta
    46321 gcagattttt atcaattgtt gaaaaaagat ttatcataag gaaagtaaat gtcaaaagat
    46381 aagaaaaatg aggacaaaga aatcctcgaa gaattgaaag agttatcaga atggcagaaa
    46441 cgaaaccaag aatatctaaa aaagaaggct gaagaagaag cggctctagc tgaggagaag
    46501 gaaaaggaaa gacaagctcg gatgggagaa gaatctgaga agtcagagga caaacaggac
    46561 caggagagtg aaacagacca ggaagattca gaatcagcta aggaagagtc tgaagaaaaa
    46621 gtagcatcct cagaggctga caaagagaaa gaagagaaag aagaatcaga gtctaaagag
    46681 aaggaggaac aggataaaaa gcttgctaaa aaggctacaa aggaaaaacc agccaaagca
    46741 aagattcctg gtatccatat cttgcgagcc ttcacgattt tatttctaag tctgctttta
    46801 ttgattgtct ctgcctactt gctcagtcct tatgcgacca tgaaagatat tcgtgttgag
    46861 ggaacggtgc aaactacagc tgatgatatt cgacaggctt caggcattca ggattcggat
    46921 tatacgatta accttctgct agacaaggca aaatatgaaa agcagattaa gtctaactat
    46981 tgggttgaat cagctcaact tgtctatcaa tttccaacta agttcactat taaggtcaag
    47041 gaatatgata ttgtggccta ctatatttct ggtgaaaatc attatcctat tctttccagt
    47101 ggtcagcttg agactagttc tgtgagtctg aacagtttac cagaaactta tttatcagtt
    47161 ctctttaatg atagtgaaca aatcaaggtt tttgtctcag aacttgctca aattagccca
    47221 gaactcaagg cgactatcca aaaggtggaa ttagccccaa gcaaggtgac atccgattta
    47281 attcgattga ccatgaatga ttcggacgaa gtcttggttc ctctatctga aatgagtaag
    47341 aaactgccat attacagtaa gattaagcct caattgtcag aaccgagtgt ggtcgacatg
    47401 gaagctggaa tctacagcta cactgtggcg gataaattaa ttatggaagc tgaggaaaaa
    47461 gccaaacaag aggccaagga agccgagaaa aaacaggaag aagaacagaa aaaacaagag
    47521 gaagagagca attgaaatca aacgacccag cgctcattgc gtcgctaggt ttaccttttc
    47581 tcttatagtt ctttagtgac catgttttta cttgacaagt gctagtagaa ataatagaat
    47641 aatagaaaac ctttaaagca gtccagagag gcagctaagg ttagacggtg aaagggtgga
    47701 gactacccat ttttcgtgga accttgctgt tggcaggttc cttttttcgt ggcttctgtt
    47761 ggccagactc tctcactagt aaaggtaaaa ggagaaacct atgcgagaac atcgtccaat
    47821 cattgctctt gattttccta gttttgaggt ggtcaaggaa tttttagctc ttttcccagc
    47881 agaagaaagc ctttatctca aggtagggat ggagctttat tacgcagcgg ggcctgagat
    47941 tgtgtcctac ttaaaaggtt tgggtcatag tgtctttttg gatctcaaac ttcatgacat
    48001 tcccaataca gtcaagtcag caatgaagat cctatctcag cttggtgtgg atatgaccaa
    48061 tgttcatgcg gctggtggtg tagagatgat gaaggctgcg cgtgaaggtc ttggaagtca
    48121 agctaaattg atcgctgtaa ctcagctcac atcaacgtca gaagctcaga tgcaggagtt
    48181 tcaaaatatc caaaccagtc tgcaagagtc tgtgattcac tatgccaaga agacagctga
    48241 agctggcttg gatggtgttg tttgctcggc tcaggaagta caagtcatca agcaggctac
    48301 caatccagat tttatctgtc tgacaccagg gattcgtcca gctggtgttg cagttggaga
    48361 tcaaaaacga gtcatgacac ctgctgatgc ctatcaaatc ggcagtgact atatcgtagt
    48421 gggacgtccc attacccaag ctgaggatcc tgttgcagct tatcatgcca tcaaggatga
    48481 atggacacag gactggaatt aaagaactag attagaaaaa taaaaggaga ataccatgac
    48541 acttgctaaa gatatcgcta gccacctctt gaaaatccaa gccgtttacc tcaaaccaga
    48601 ggaacccttc acttgggcat ctggtatcaa gtcaccgatt tacactgata atcgtgtgac
    48661 actagcctat ccagaaactc gtaccctaat tgaaaatggt tttgtggatg ctatcaaaga
    48721 agcctttcct gaagtagaag tgattgcagg aactgcaaca gcagggattc cacacggagc
    48781 cattattgct gataagatgg acttgccttt tgcctacatc cgtagcaaac caaaagacca
    48841 cggagctggt aatcaaatcg aaggtcgcgt agctcaaggt caaaaaatgg tagtggttga
    48901 agaccttatt tcaacgggtg gttcagttct tgaagctgta gcagcagcca agcgagaagg
    48961 agcagatgta cttggagttg tagcgatttt cagctaccaa ttgccaaaag cagataagaa
    49021 ctttgcagat gctggtgtta aacttgtgac gctttcaaac tatagcgagc ttatccatct
    49081 agcccaagaa gaaggttaca tcacgccaga gggccttgat cttctaaaac gctttaaaga
    49141 agaccaagaa aattggcaag aaggttaggt cagtaagata aagagagacg aggctaccga
    49201 gtctctttta ccattttatt taaaatatga caatatttta aataaaataa ttgacaacgc
    49261 tttcttttat tgatataatg aaaatgtaat atgtatcaaa ttgatcaatc aactatcttg
    49321 tttatcactt cttaagagga cgatgtcatg aaaagaagaa aaatatattc cttttttgcg
    49381 tagttacaaa tgcatctagt ttgtttctcc ctacagtttt agctagacag attggagatt
    49441 atgatttaac gtcgccgcgt tggggttcgg atacaactag tgagcttgag aaagaaaact
    49501 cctctgctgg aattaataat aatgacagca ctggtggcgg taaaaggtta aatacctcta
    49561 ttcgtagcgc ctatagtggg tcagatatta ccccggtata ttcattgggg tctggctcta
    49621 ggattgtcat gtactataat ggaggtggtg acaattatat tggttctggt actagattag
    49681 ctatggcgcc acaatttgga aatcatgtaa gaattcatac ttcaggttct tggaatccag
    49741 attcttatta acttacttgt cagagtaagc cttaaagatg gttgattgtg ggtgtagcat
    49801 gaaaaaagaa tgctacaccc tatttttatt ataaggagga gtaaggatgg aatttttcat
    49861 ttgtaatctt gtacgagtcg ttcaatcacc tcgattttat atgtctttat ttttgaccct
    49921 tctttgcatg agtttaggaa atttccttgc tttcaatggt atttataaaa ttgaaggttt
    49981 atcgattttt tttgccgctt cttctattcg aggattttca ccgattagcc tagtagctgc
    50041 acttatctgt acactgccct attctagtca gataatagag gatgctgaga gtcattttct
    50101 aacagcacaa ttgtgtcgaa tttctaaaaa gaagtatctg gctattgtgg gtagtactgt
    50161 aattatttct tcttttctag tcttttttct cccctattta ttattattag gaattaatct
    50221 tttagtgact ccttatcagg aaatttatat tggagattat agtggtgcct taaaagaatt
    50281 atttgattcc aatcagtttc tctatagtct tgtaacgact ctctggtatg gagtttgggg
    50341 cgctgtgttc tctatttttg gactagctag tgctttgcta gtgaagaaaa aaataggagc
    50401 tattttcatc ccagttgcct atatgatggt tggtggtatt ttttgggcta ttttagggct
    50461 atcttactta gaacctgtga caacgctagc tttgggatat cagaaagata tcagtctttc
    50521 cttagttagt gctcatcttg cttttatttt atttgttagt tgtttggttg tttatggtac
    50581 attttttcta cattcagagg actatgtata atgaaacaat ttgttcaatt ttataaaaaa
    50641 gatttcttag cagtattggt ttattttata ttactgctat cctgtgtttt atctagtaca
    50701 gtatatttat tgcgctgtcg ccaatattca atccatccaa atgtattaga atggatctta
    50761 gttttacttc aagatatgac gactggagta tattgctttc cgttcacata tatattgttc
    50821 tttttttatt tgatgaataa ctattttaat aggttggagt gtcgcattcg tctgaaatca
    50881 attaagcact ttaccagttt tagtttcaaa ttagcagctc ttagtacggg gatttggacg
    50941 gcgactttat ttttattgat ttttctaatt gcatttagta atggttttag cttctctttg
    51001 gagataaagg aggttgattt tttaagagaa ttttatggta taagtattgc aaacaatgct
    51061 agtttcttta taggattttt tttctcttat atagcatact atttcttttt atccttactt
    51121 actattagca gtttttcttg gtttaaaaaa tcaaacatga gcttagtatt tctgtttact
    51181 tttttatttg tagaatcctt attctggatt tatcagttgg acaatgggat aattggatta
    51241 ttgccaattt ttcagtatat ggtaaattcc aatccgtatg cattgattta ttggcttaca
    51301 ttactatcta tcataattcc attgactgta ttttctgttc atagaaactg gaggagagtg
    51361 taaaagttgg aaatgggaaa gttaagtagt cacatgtgga ggttgaatca gataatctat
    51421 accaagtact tttggggtta tgttcttttt tggatattga tttgtttagg attatggtat
    51481 tggttagaag gaaatgatag acttgttata gaaattttaa aagggcctaa tctgagtcaa
    51541 aactcttttt tagtcttatc tatatggttg cttcattggt ttattattca tacatttttt
    51601 ctagcagttg tatatcgtag aagagcatcc gatttcttta tggaagtgat tcgattttct
    51661 tctattaagc tctggattag gtatcagatt tggacctgtt ttctttatgg actcatttta
    51721 atcatggtaa aagttctagt gattcaattt atgttacagt taccaaactg ggatatagga
    51781 gttttgttta tagttgattc tttgaatgct tgtgtgttag tcttgttttg ctttatgtta
    51841 tacgcactag gagcgaatgt acaaatgaac tttgcttgcg ttagtttctt tttactcatg
    51901 attgtgtttg gtggtctatt tgtaggaaat cgaactaatt atctatttta tattttgaat
    51961 cgagggaatg gagatatagg acgagattta tttcttcagt tgctattttt agtctttctt
    52021 tttcaaagca ttttctattt cactcgtcaa aagaggaggt ttatagaatg aatgaaataa
    52081 ttacattaaa aaatattgag ttgaaattaa aaaagacatg tgtttttcaa aaccttaact
    52141 ttagttgtaa acagggggaa attataggaa ttactggtgc gaatggctca gggaaaagtg
    52201 tattgtttaa attaatagct ggtttatata gtccgtctta tggagaagtg ttaatcaatg
    52261 gggaaaatat tgttcctgag agaaaaattc cagctaattt gggagctttg attgaagaac
    52321 ctggttttat aaattattat agtggcttta agaatttaca atatttggca agcatacgag
    52381 gagtagttgg taatcaggaa atcaatgata cactgaaaat agttggtcta tatgagcaaa
    52441 aagaccagaa agttaaaact tattcgctag gtatgaggaa aaagctaggg attgctcaag
    52501 caattatgga gaatccctct attcttttac tagatgaacc tatgaatgcc ttggataaat
    52561 caagtgtaga aaatatgaga acattgttta gaaagctctc tagtgaaaaa gggacaacaa
    52621 ttttgattgc tagtcatagt gaagaggata ttcgtatctt atgtgataaa gtatatgcaa
    52681 tagaagataa agtatgtaca ctgtgttcag attgaacatc ttagatagac tcaggatgtt
    52741 ataggtaaaa tcttaaaaag ggattggagc ttaaaatcca gttcctttta agagttaatg
    52801 actaatcaac ttttccacct tcaacaacca ggtcatctgc tttagcagcg tcaccgtagg
    52861 ttgggtgaag tgtcttttca taggccttgt ggaagaagtt ttccttgcct aatttttcaa
    52921 tatctttatt gatgaagtct agcaattctt ggttgccttt ttgaactgct gccgcaatgg
    52981 tatcgggatc accgagggaa gtaattccta cttcaaatcc tttattttca agcgcccaag
    53041 ctagaacttc cgtattgtca gttgaaaagg catctccacg tccgtcaaga agagcttggt
    53101 aagagtcact gtattggtcg tatttttgga gtttgatttc tggatgattc ttttcaaaat
    53161 aagtctcagc agtcgttcct tttgtgacaa ttaaggtttt accttcaagt tgtttgacgt
    53221 ctgtaatgag accagtctta ggtgatacga cacccagaga aactttcata tatggaaggg
    53281 caaaatcaac ttgtttctta cgttcgtcag ttactgtaaa gttagcaaga gtaatatcta
    53341 ccttgtttga aatcaagtat tccgcacggt tggcagcatc gactgaaatg tatttaacct
    53401 tgacaccaag gtcttgagct agttggttcc ctagttcaat atcgtagcgt agccttggta
    53461 agaaccatca ttgtcaacgt agccaaacgg ttttttatct ccaaacacgg cgattcgcag
    53521 ttcaccgctt tttttgattt catcgatagt gcgagctttg gcagttgttt ttccagagga
    53581 tgaaccagcg tttccacctg agctacaagc agtgataaag ataagggcaa aggcaagtgc
    53641 taaaacagtt aagagtggtt tgaatagttt cataagaatc tcctttatag atatgagccg
    53701 aattggctaa agtcaaagac gtttaaaaat tcctgggctc gtttggtttg cggattggta
    53761 aagaaggctt gagctgttcc ttcttcagcg attttccctt ggtcgaggaa gataatccgg
    53821 tcagtaatgg cttgggcaaa ctgcatttcg tgggttacta aaatcatggt acggccttct
    53881 tgggccaaat cattgataag ttccagcacc tcacgcacca tttctggatc cagcgaagca
    53941 gtcacctcgt caaaaaggat gatttctgga tgcattagga gggcacggac aattgcaaca
    54001 cgttgcttct gtccaccaga taattgacgg gcaaagctat gttgtttatc cagcaaaccg
    54061 acacgctcta gtaattgcaa agcttcttcc gttacttctt tcttgtccct tccttgagct
    54121 ttgatagggc ctaggatgag gttttgtaag acatccagat ggggaaagag ttcataactt
    54181 tgaaagacca tgccaatctt ttggcgaact aggtgaaaat cttttttatt ttcaacgata
    54241 gactgaccat ccagaagaat atctccacct tgaatacttt ctaagccgtt gaggcaacga
    54301 aggagggtac ttttcccaca accagatggc cctaggatga caacaacttc cccttttttg
    54361 atttctagag aaagtccttg gaggatggga ttgtctccga aggatttttt tagttccttg
    54421 atttctaaga tagtttcaga catttagttt ctccaatgtt tttctaagtg agtggatagt
    54481 ttggaaatag ggtagcaaac tgcgaaatat aagactagaa tggttccata aatccaaaat
    54541 gaagcagttg gggatggtca ggcgattgct atcgatgatt tgttgtccaa ctttggtcac
    54601 ttccacaacc ccaatcaaaa caactaatga agtggtttta atcatccgag tgacaagatt
    54661 gatagcctgc ggtagcagtc ttcttaagac ttgtgggatg atgatgtggt agtaaagttg
    54721 aacattagtc aagccgagtg cctatccact ttcaaactga tgtttaggga gagaagtgat
    54781 agctccacgt accaagtctc ccatttcagc tgttccccag agggtaaaaa tgataatagc
    54841 tgaagtctca cctgagatat tgatattaaa gtttcgagcc aagccaaagt aaacgatgaa
    54901 gagtagcacc agctggggca tgatacggat aaattccaga tacaatcgtg ttaaaaatcg
    54961 tatgattcta gaatgggagg tcatgatgat tcccatgact gttccgaaca tcatggataa
    55021 gaggacagac aggatggata tcccaatcgt aacgcccaac ccctgtaaga ttctcaggag
    55081 attatttcct tgaaagagta cttggattcc cgaatcctgc atggcgggtc ctcctttcta
    55141 tccagctaaa gaccagtgag atgggtagca gcatgatcag ataagcaact accaacatag
    55201 ctagcgcaat gtctgtctca tagtagagac caatcaaatc cttggcgacg tacatgaggt
    55261 cggccaaagc cactgctgag aaaacagagg ttttcttgat aaggaaaatg acattggcac
    55321 taaaggaggg gagtaccacc gctgttgctt gcggaagaac cacatagcga aagacctgta
    55381 gaggtgtcag accaatagcg aggccaatct cctgctgggt ttgactgatg gcttccagcc
    55441 cacttcggaa agattctgcc atataggagc ctcctaaaaa gacaagtcca agcgttgcac
    55501 agacttctga agataggaca atcccgattc ggggaagacc gaagtagaga aagaagagtt
    55561 gaatcaaaag gggcgtatta cgtgacaatt caatgtaggc tgtcgctact tgcgctaaaa
    55621 cagggattcg ataatgtcgg atgatactaa cgattaaacc gagcagaaag gatcccaaaa
    55681 ttccccaaac tgcaatatgc aaggtcagaa agaatgcctt ttgatatagt ggtagatatt
    55741 gttcaacaat ggatcaatcc aaaaatagaa cctcccatct agaaataata cagttattgt
    55801 agcacttaaa atcttctttg gataatatct attttttatt gccgttataa ggatttttat
    55861 catagacata aaatttctga aatttccaaa caaaatattt gaaaagtttt gaaaaaagag
    55921 ttaatatatt tttataatat acaaagtaaa cgcttactta ttaaggagga cattttatgt
    55981 catacaaaac aagcaatgca gaaggtcatg tagatttcat caatacctat gatttggagc
    56041 caatggcgca acaagttatt cctaaagcag catttggcta tatcgctagt ggggcggaag
    56101 atactttcac ttctttccag tgattttagc gtcaggttct ttttagtttt taaagattat
    56161 ccgtgaattt cttgcttatt tatgataaaa tgggagtatc gcaaaaaatg actcatcgta
    56221 ttcaattttg agtaaaacta ggaggatccc atgtctacag aacatatgga agaactaaat
    56281 gaccagcaga tcgttcgccg tgaaaaaatg gctgcgctcc gcgaacaagg aatcgatcct
    56341 ttcggaaaac gttttgaacg tactgcaaat tcacaagaat taaaagataa atatgccaac
    56401 ctcgataaag aacaattaca cgataaaaac gaaacagcta ctatcgcagg acgcttggta
    56461 accaaacgtg gtaaaggaaa agttggtttt gcccaccttc aagaccgcga aggccagatt
    56521 cagatctacg ttcgtaagga tgctgtcggt gaagaaaact acgaaatctt caaaaaagca
    56581 gaccttggtg acttccttgg tgtcgaaggt gaagtgatgc gtacggatat gggagaactc
    56641 tctatcaagg caacccacat cacacacttg tctaaggctc ttcgtcctct tcctgagaaa
    56701 ttccatggtt tgacagacgt tgaaacaatt taccgtaaac gttaccttga cttgatttct
    56761 aatcgtgaaa gctttgaacg ctttgtcact cgttcaaaaa tcatctctga aatccgtcgt
    56821 taccttgacc aaaaaggatt ccttgaagtg gaaacacctg ttcttcataa tgaagccggt
    56881 ggtgctgctg cccgtccatt tatcacccac cacaatgccc aaaacattga catggtgctt
    56941 cgtatcgcga ctgagcttca cttaaaacgc cttatcgtgg gtggtatgga acgtgtctat
    57001 gaaattggcc gtatcttccg taacgaagga atggatgcta ctcataaccc tgagttcact
    57061 tctatcgaag tttaccaagc ttatgcagac ttccaagata tcatggactt gacggaaggc
    57121 attatccaac atgctgctaa atcagttaag ggcgatggcc cagtcaacta ccaaggtact
    57181 gaaatcaaga ttaacgaacc atttaagcgt gttcatatgg tggatgctat cagagaaatt
    57241 actggtgtcg atttctggca agacatgact ttgaaagaag ctaaagctat cgctgctgag
    57301 aagaaagttc cagttgagaa acactacact gaggttggtc acatcatcaa tgccttcttt
    57361 gaagagtttg ttgaagaaac tttaatccaa ccaacctttg tctatggaca tccagtagct
    57421 gtatctccac tcgctaagaa aaatcctgaa gaccaacgct ttactgaccg tttcgagctc
    57481 tttatcatga ctaaggagta cggtaatgcc tttactgagc tcaacgaccc aatcgaccaa
    57541 cttagccgtt ttgaagccca agctaaagct aaagaacttg gtgatgatga agcgacaggc
    57601 atcgactatg actacatcga ggctcttgaa tacggtatgc caccaacagg tggtttggga
    57661 atcggtatcg accgtctctg catgctcctc actgatacaa caactatccg tgatgtattg
    57721 ctcttcccaa caatgaaata aat
//
LOCUS       DAVAGB010000007        54907 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVAGB010000007 DAVAGB010000000
VERSION     DAVAGB010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54907
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.007"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(33..1001)
                     /locus_tag="VQO19_000494"
     CDS             complement(33..1001)
                     /locus_tag="VQO19_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET1348798.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLNLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            1137..1994
                     /locus_tag="VQO19_000495"
     CDS             1137..1994
                     /locus_tag="VQO19_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HET1348799.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            1981..2760
                     /locus_tag="VQO19_000496"
     CDS             1981..2760
                     /locus_tag="VQO19_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HET1348800.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            2784..4136
                     /locus_tag="VQO19_000497"
     CDS             2784..4136
                     /locus_tag="VQO19_000497"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HET1348801.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            4210..4584
                     /locus_tag="VQO19_000498"
     CDS             4210..4584
                     /locus_tag="VQO19_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HET1348802.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            4586..5434
                     /locus_tag="VQO19_000499"
     CDS             4586..5434
                     /locus_tag="VQO19_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET1348803.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            5700..6467
                     /locus_tag="VQO19_000500"
     CDS             5700..6467
                     /locus_tag="VQO19_000500"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HET1348804.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            6479..7663
                     /locus_tag="VQO19_000501"
     CDS             6479..7663
                     /locus_tag="VQO19_000501"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HET1348805.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHNPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            7660..9531
                     /locus_tag="VQO19_000502"
     CDS             7660..9531
                     /locus_tag="VQO19_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET1348806.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMVNQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(9674..10858)
                     /gene="mntE"
                     /locus_tag="VQO19_000503"
     CDS             complement(9674..10858)
                     /gene="mntE"
                     /locus_tag="VQO19_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HET1348807.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLENRF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            11162..13858
                     /locus_tag="VQO19_000504"
     CDS             11162..13858
                     /locus_tag="VQO19_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HET1348808.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            13871..14662
                     /gene="yghU"
                     /locus_tag="VQO19_000505"
     CDS             13871..14662
                     /gene="yghU"
                     /locus_tag="VQO19_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HET1348809.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTEDVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            14778..15188
                     /locus_tag="VQO19_000506"
     CDS             14778..15188
                     /locus_tag="VQO19_000506"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET1348810.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETTRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            15200..16795
                     /locus_tag="VQO19_000507"
     CDS             15200..16795
                     /locus_tag="VQO19_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348811.1"
                     /translation="MKRIVCELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            16974..17138
                     /locus_tag="VQO19_000508"
     CDS             16974..17138
                     /locus_tag="VQO19_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HET1348812.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGIALV
                     LAAVWLGWPK"
     gene            17217..17945
                     /gene="yaaA"
                     /locus_tag="VQO19_000509"
     CDS             17217..17945
                     /gene="yaaA"
                     /locus_tag="VQO19_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HET1348813.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(17996..19480)
                     /locus_tag="VQO19_000510"
     CDS             complement(17996..19480)
                     /locus_tag="VQO19_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET1348814.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILEGLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYIPGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            19696..25296
                     /locus_tag="VQO19_000511"
     CDS             19696..25296
                     /locus_tag="VQO19_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HET1348815.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKLAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKDKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETN
                     PAATTDRSAVDSAVLPTSTAAKVETTSAPASINEILKPGLSLSDARQNPAIRKEDLDK
                     GYSGFRAAPAPTNKLVTNLGNNTVFTDISRGSHTFRGNGNSRGGNPIHFDVTTTRVGN
                     RVEFSIAYSGPGEFVNNNFLLDKGNGFGEPSRATISTNRLRDQTKDIRKGANFVSHSS
                     YSLTSAVETNSNQTIRFSLPIANPNGDLSVRLRPVTFNVGQGESGSATSNDPYSNSNY
                     YFREKPLLLDANPNGGTNNKTVSEDIDFQTVYLPTSKLPEGQTRLVREGEKGQRQIIY
                     KVHQLGNETILGLPISNSVIKEVKPRIMQIGVAKDLIDTVKPRVDQNKVGDTNNLTFY
                     LDNDGNGVYTEGVDELVQKIAIKDGAKGEKGVQGERGLTGAQGQAGRDGVTPTVTVKD
                     NKNDGTHTITINDGRGNVASTVVRDGFDGASPLVATQRNEADKTTTVIFYYDQNGNNE
                     LDASDKKLKEVIIADGAKGEQGLQGRDGAQGPKGADGQRGPAGPQGPKGEQGNPGTPG
                     KDGKSLIAVKNGTETKVYVEDPARPGQPLNPNQPLATITDGRNGTNGQSPTITATRSV
                     QNGKNGVLVTITPVGGRPQTTFVEDGQKGADGKTPTVTITEGQNGTHTLTVHNPGSPD
                     VTTTIRDGATGQAGRDGKDVLNGKVNPQPNQGKNGDKYINTETGDVYVKNNGNWDKEG
                     NIKGPKGDKGADGAKGEKGDQGERGLTGAQGAKGADGAVGRDGRDGKDVLNGKANPEA
                     HQGKDGDKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGERGEDGKTPEVTVTPGKDG
                     HSTDITFTVPGKDPVTVNVKDGENGLNGKTPKVDLLRVQGKNGNPSHTIVTFYTDENN
                     DGKYTPGTDELLGSEMIKDGAKGADGRDGKSLLTVKDGKETKVYQEDPANPGQPLNPE
                     KPLAVIRDGVDGKSPTVTAVRKDEAGHKGVEITVDNHDGSQPTTVFVQDGAKGETGAT
                     GQDGQTPTITTQRGQDGQSTVVTITTSGKDPVTFTVKDGKNGKDGRAPKIKVEDITSP
                     SRIRRDTDAAATPTRNGIRVTVYDDVNDNGVYDGGVDKVLNSKDIYNGIDGRDGSAPT
                     ITTKDNGDGTHTITVQNPDGSESTTVVKDGKDGKTANITTTENPDGSHTITVTNPDGS
                     TKETVVKNGKDGKTPKVEVTDNNDGTHTVKVTDGDGNVTNAIIKDGKDGKAATATTTE
                     NPDGSHTVTITNPDGTKNEFVVKNGRDGVDGRTPTASVRDNGDGSHTIVITNPEGVTT
                     ETTVRDGKSPKVTITDEQNGTHKISVLNGDGTTTETIITDGKSPVATVRDNQDGTYTI
                     RVENGNGTVSETTVRDGKSPTAKVVDNGDGTHTITVVNSDGTTTTTTVRDGREPKLEV
                     IDNNDGSHTIKVTGADGKGTTTTIFDGKSPKANIVDNGDGTHTLTIVDSDGREYKSII
                     KDGKDGKDSVSPTVTVKNNNDGTHVVTITNPDGSKTEMVIKDGKDGKSPKVSVEDNGD
                     GSHTITIINSDGTVTKTVIKDGKDGRDGRDGRDGKDGKDGKCGCQDKPVTPSNDKPVP
                     PTPNVPTPEVPVKPVPAVPEQPVVPTPAQPATPVNANPVAPTTGKENRGDKLPETGSQ
                     SDYISVLLGSGILLSLYVGRRKED"
     gene            complement(25533..26081)
                     /locus_tag="VQO19_000512"
     CDS             complement(25533..26081)
                     /locus_tag="VQO19_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET1348816.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALASKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            26402..26890
                     /locus_tag="VQO19_000513"
     CDS             26402..26890
                     /locus_tag="VQO19_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HET1348817.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQVDQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            26887..28074
                     /locus_tag="VQO19_000514"
     CDS             26887..28074
                     /locus_tag="VQO19_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET1348818.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEVA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEESEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            28067..28291
                     /locus_tag="VQO19_000515"
     CDS             28067..28291
                     /locus_tag="VQO19_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET1348819.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEV"
     gene            28448..29794
                     /gene="asnS"
                     /locus_tag="VQO19_000516"
     CDS             28448..29794
                     /gene="asnS"
                     /locus_tag="VQO19_000516"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HET1348820.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            29947..30237
                     /locus_tag="VQO19_000517"
     CDS             29947..30237
                     /locus_tag="VQO19_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HET1348821.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            30249..30719
                     /gene="ssbA"
                     /locus_tag="VQO19_000518"
     CDS             30249..30719
                     /gene="ssbA"
                     /locus_tag="VQO19_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HET1348822.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            30751..30990
                     /locus_tag="VQO19_000519"
     CDS             30751..30990
                     /locus_tag="VQO19_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HET1348823.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            31285..32685
                     /locus_tag="VQO19_000520"
     CDS             31285..32685
                     /locus_tag="VQO19_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HET1348824.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIGKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            32687..33046
                     /locus_tag="VQO19_000521"
     CDS             32687..33046
                     /locus_tag="VQO19_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HET1348825.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHYLKKKK"
     gene            33100..33849
                     /locus_tag="VQO19_000522"
     CDS             33100..33849
                     /locus_tag="VQO19_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HET1348826.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPHSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            33839..34138
                     /locus_tag="VQO19_000523"
     CDS             33839..34138
                     /locus_tag="VQO19_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HET1348827.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            34209..35144
                     /locus_tag="VQO19_000524"
     CDS             34209..35144
                     /locus_tag="VQO19_000524"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HET1348828.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            35231..35743
                     /locus_tag="VQO19_000525"
     CDS             35231..35743
                     /locus_tag="VQO19_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HET1348829.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAAFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERDLHDSDF"
     gene            35768..36376
                     /locus_tag="VQO19_000526"
     CDS             35768..36376
                     /locus_tag="VQO19_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HET1348830.1"
                     /translation="MFGELIRYLDQYEDVILREIKSQFPDVAVDKLMEEYIKASLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDRKYELAIDFDKERLTFYLA"
     gene            36477..36671
                     /locus_tag="VQO19_000527"
     CDS             36477..36671
                     /locus_tag="VQO19_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET1348831.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(36717..38162)
                     /locus_tag="VQO19_000528"
     CDS             complement(36717..38162)
                     /locus_tag="VQO19_000528"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HET1348832.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKILAFTGTKGKTTAAYFAYNILSQRYPTALLSTMNTTLDGTTFFKSSFS
                     TPENIDLFDMMAQAVKNGRSHLVMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            38268..39890
                     /locus_tag="VQO19_000529"
     CDS             38268..39890
                     /locus_tag="VQO19_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET1348833.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            40091..42052
                     /locus_tag="VQO19_000530"
     CDS             40091..42052
                     /locus_tag="VQO19_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET1348834.1"
                     /translation="MKKSKSKYLTLAGFVLGTGVLLSACGNSSTVSKTYNYVYSSDPS
                     SLNYLAENRATTNDIVTNLVDGLMENDQYGNYVPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGI
                     KALDDQTVQYTLARPEPYWNSKTTSTILFPVNADFLKSKGDDFGKVDPANILYSGPFL
                     MKAFVSKSVIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQDALVRNFTDGAYSYARLYP
                     NSSSFEGIKEKYKDDIIYSMQDATSYYWNFNLDRQAYKFTSKTTDIEKKSTQEAVLNK
                     NFRQAINFAYDRTSYGAQTQGEDGATKILRNLVVPPTFVSIKGKDFGEVVASKMVNNY
                     GKEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDATVDQASKKGIQE
                     VSSMKQSIEAALGTENVVIDIQQLSTEDYDNSSYLAQTAIQKDYDLYNGGWSPDYLDP
                     STYLDIFSVKNGGVLQNLGLDPGEANDKAKAVGLDTYTQMLEEANKEQDPAKRYEKYA
                     DIQAWLIDSSLAIPNVSLGGTPSLRKTVPFSAPYSLAGNKGVESYKYLKVQDKIVTTD
                     EYAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            42224..42457
                     /locus_tag="VQO19_000531"
     CDS             42224..42457
                     /locus_tag="VQO19_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HET1348835.1"
                     /translation="MKLKLLRVDTKVIMWSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKR"
     gene            42463..43905
                     /locus_tag="VQO19_000532"
     CDS             42463..43905
                     /locus_tag="VQO19_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1348836.1"
                     /translation="MRKKVIEGLIYAEKSFFDKSQSGELTSAIVNDMSVIREFLITTF
                     PNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMMFIILPLSNISEKYSRRLQEEIG
                     FLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSFETPFALLFI
                     FATIVVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTIYSSSKGSSVA
                     LENLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENRPVLKDITCSIFKGQKIAFVGPS
                     GSGKSTIVRLLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDN
                     LCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIART
                     YLKDAEILIFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHSLSTVKDVDCIFFLE
                     EGKITGSGTHKELLENHERYARFVQEQMIE"
     gene            44063..45157
                     /locus_tag="VQO19_000533"
     CDS             44063..45157
                     /locus_tag="VQO19_000533"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET1348837.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            45165..46331
                     /locus_tag="VQO19_000534"
     CDS             45165..46331
                     /locus_tag="VQO19_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET1348838.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVMDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            46424..49522
                     /locus_tag="VQO19_000535"
     CDS             46424..49522
                     /locus_tag="VQO19_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET1348839.1"
                     /translation="MAKLIPGKVRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVSDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            49570..50187
                     /locus_tag="VQO19_000536"
     CDS             49570..50187
                     /locus_tag="VQO19_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET1348840.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            50198..51532
                     /locus_tag="VQO19_000537"
     CDS             50198..51532
                     /locus_tag="VQO19_000537"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HET1348841.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            51542..52006
                     /locus_tag="VQO19_000538"
     CDS             51542..52006
                     /locus_tag="VQO19_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET1348842.1"
                     /translation="MEIPIKIIQASKFDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEETLLYATSQGYSMIWFNPFYLEEQ"
     gene            52003..52497
                     /locus_tag="VQO19_000539"
     CDS             52003..52497
                     /locus_tag="VQO19_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET1348843.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            52578..54233
                     /gene="mltG"
                     /locus_tag="VQO19_000540"
     CDS             52578..54233
                     /gene="mltG"
                     /locus_tag="VQO19_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HET1348844.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADESQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATEIVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            54304..54786
                     /gene="greA"
                     /locus_tag="VQO19_000541"
     CDS             54304..54786
                     /gene="greA"
                     /locus_tag="VQO19_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HET1348845.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
BASE COUNT        16694 a        10236 c        12390 g        15587 t
ORIGIN      
        1 gccacgaatc ctatgtgact agtggttctt ttttataaac tggtagagtg ttttggttgt
       61 actttttgtt cagggtcaat gtagttgata gcgttgttga cagcagttgg agcttctccg
      121 aggcctgtcg caatcagatc aatttttccg tcatagtagc agcagtcacc gatagcatag
      181 atacctgctt ggctggattc ctgtttgctg ttgacgataa tcttgtgacg gttgaggttg
      241 agcccccagt ttttaaggtt accgacagaa gatttgaaac catagttgac aaagaggtgg
      301 tctaggtcaa tggtttcagt ttcatcagat ttgacttttg tgatttcaag tttatcaagt
      361 gtttttccat ttccaaggag ttggctaggg gcgaatggtg tcttgatggt tacagatgat
      421 tcttgcaagg cttgaacact gtgttccaag gcacggaaat tatctctgcg gtgaacaagg
      481 gtagttggtg cgattttttc aaaagccaaa gcccaatcca cagccgagtc tcccccacca
      541 agaatcgtca ctttcttacc agcgtattgc tgaatgttag aaacgtggta gtggatattt
      601 tcatagccct caacaccttc aagttccagc ggacgtggtt tgaaggcacc gccacccata
      661 gcgataatga ctgttttagt caggtgactt cctttagaag ttgtgatggc aaattcttct
      721 tcttgtttgt caatctcaag aaccgtttca ttgagatgaa taggggtatc aaatccattt
      781 agctgttcaa tcaagcggtt agtcaactct tctccagtca ggtttgggaa gcctggtacg
      841 tctaggattt ccttttcagg gtagagaata gcaggttgtc cacctagctg gggaagagag
      901 tcgatgattt gaaccttggc ttggcgtagg tgggcataaa aggctgcaaa aagcccgaca
      961 ggaccaccac ccacaatggt aatatcatag agttgagaca tagtttctcc tttgtttttt
     1021 ctagtcagtt tattttatca tatttttgtt caatgtaaaa tggactagga tagggaaaaa
     1081 aatgccagaa aatggtataa taggacgaaa gtgttttgat agggaggata tcagggatga
     1141 attttcaaca attatccaat ctgcaatatt ggaccagttt gtttgcaagt ccatggacga
     1201 tagctatcaa tctgattgat attttgattg ttgcttatat tttataccat tttacaaaag
     1261 ctattgcagg aaccaagatt atgattttgg tacgtggagt tttggtgttt attttagctc
     1321 aaatccttgc aaatatgatt ggtttgacta cgatttcttg gttaatcaat caaattatta
     1381 cttatggggt tattgcggcg gttgttatct tctctccaga gattcggact ggtttggaac
     1441 gtttgggaag agcgacagat ttcttttcca atgcccctat tagtgctgag gaacagatga
     1501 ttcgtgcctt tgttaagtct gttgaataca tgagtcctcg taaaatcggg gccttggttg
     1561 ctattcagcg tgtacgtacc ttgcaggagt atatttcgac aggaattccc ttggatgcta
     1621 agatttctgc agaacttctc attaacattt ttattcccaa cactccccta catgatggtg
     1681 cggtgattat caaagaagaa cgtatcgctg tgacgtctgc ctatctgccc ttgacaaaaa
     1741 acacagggat ttccaaggaa tttgggacca gacaccgggc ggctatcggt ttatcagaag
     1801 tctcagatgc cttgactttt gtcgtatcag aggaaacggg aggaatttcg ataacctata
     1861 atggaaggtt taagcacaac ctaacacttg atgaatttga aacagaatta cgtgaaatct
     1921 tacttccaaa agaggaagtg ggtcttagtt ttaaagaacg attgctagga ggatggaaac
     1981 atgaaaaaaa atagtttata tatcatatcc tcactctttt ttgcttgtgt cttatttgtc
     2041 tatgctacgg cgacgaattt tcaaaacagt accagtgcta ggcaggtaaa aacggaaacc
     2101 tatactaata cagtaacaaa tgtccctatt gacatacgct ataatagtga taagtatttt
     2161 attagcggtt ttgcttcaga agtatcagtg gtcttgactg gtgcaaatcg cctatcgcta
     2221 gctagtgaaa tgcaagaaag tacacgtaaa ttcaaggtta ctgctgacct aacagatgcc
     2281 ggtgttggaa cgattgaagt tcctttgagc attgaagatt tacccaatgg gctgaccgct
     2341 gtggcgactc cgcaaaaaat tacagtcaag attggtaaga aggctcagaa ggataaggta
     2401 aagattgtac cagagattga ccctagtcaa attgatagtc gggtacaaat tgaaaatgtc
     2461 atggtgtcag ataaagaagt gtctattacg agtgaccaag agacattgga tagaattgat
     2521 aagattatcg ctgtcttgcc aactagcgaa cgcataacag gtaattacag tggttcagta
     2581 cctttgcagg caatcgatcg caatggtgtt gtcttaccgg cagttatcac tccgtttgat
     2641 acaataatga aggtgactac aaaaccagta gcaccaagtt caagcacatc aaattcaagt
     2701 acaagcagtt catcggagac atcttcgtca acgaaagcaa ctagttcaaa aacgaattaa
     2761 aaatagaaaa ggattttata acaatgggta aatattttgg gactgatgga gtccgtggag
     2821 aagctaacct agaactaaca ccagaattag cctttaaact aggacgtttt ggaggctatg
     2881 ttcttagtca acatgaaacg gaagcgccga aagtctttgt aggacgtgac acacgtattt
     2941 caggggaaat gctggaatcg gccttggtgg caggtctcct ttcagtaggg attcacgtat
     3001 acaaacttgg tgtccttgca acaccagcag tagcttactt ggttgaaact gaaggagcaa
     3061 gtgccggtgt catgatttct gctagccaca acccagccct tgataacgga atcaagttct
     3121 ttggcggtga tggcttcaaa ctagatgatg aaaaagaagc agaaattgaa gccttgctag
     3181 atgctgagga agacactctt cctcgtccaa gtgcagaagg cttaggaatt ttggtagatt
     3241 atccagaagg cttgcgtaag tatgaaggat accttgtttc aactggaact cctcttgatg
     3301 gaatgaaggt tgccttggat acagctaatg gagcagcttc taccagtgcc cgtcaaatct
     3361 ttgcagacct tggtgcccaa ttgacggtta tcggggaaac accagacggt cttaacatca
     3421 accttaatgt tggttcaaca catccagaag cccttcaaga agtggtcaaa gaaagtgggt
     3481 cagctattgg tttggccttt gatggagaca gtgaccgctt gattgctgtt gatgagaatg
     3541 gtgacatcgt cgatggtgac aagattatgt acatcatcgg aaaatacctt tctgaaaaag
     3601 gacaattggc tcaaaataca attgtgacaa ctgttatgtc taaccttggt ttccacaagg
     3661 ccttgaatcg cgaaggtatt aacaaggcag ttactgcagt tggtgaccgc tacgttgttg
     3721 aagaaatgag aaaatcaggc tacaaccttg gtggtgaaca gtctggtcac gttatcttga
     3781 tggattacaa taccacaggt gatggtcaat tatcagcagt tcaattgact aaaatcatga
     3841 aggaaactgg taagagctta tcagagttgg cggcagaagt aacgatttat ccacaaaaat
     3901 tagttaatat ccgagtggaa aacgtcatga aggaaaaggc catggaagtg ccagctatca
     3961 aggccatcat cgagaagatg gaagaagaaa tggcggggaa cggccgtatc cttgttcgtc
     4021 caagtggaac agaacccctc ttgcgtgtta tggcagaagc gcctacaaca gaagaagtag
     4081 actactatgt tgataccatc acagatgtag ttcgtgctga aattgggatt gactaaatcc
     4141 tagaaaacta gatgaaaata aaaaattatg gtacaatagc ttataatatt gtagccgatg
     4201 gagaaagaca tgaatcttaa acgtgaacaa gaatttgtta gtcagtatca ttttgatgcg
     4261 cgtaattttg aatgggaaaa tgaaaatgga gctcctgaaa ccaaggtgga tgtgaatttc
     4321 caattgctcc aacatgacca agaaaatcaa gtgacttcct tgattgtcat cttgagcttt
     4381 atgattgtat ttgataagtt tgtcattagt ggaacaatct cacaagtaaa ccatatcgat
     4441 ggccgtattg tcaatgaacc aagtgaattg aaccaagaag aggtggaaac cttggctcgt
     4501 ccatgtttga acatgctcaa tcgtttgact tacgaagtga ctgaaattgc attagactta
     4561 ccaggaatta atttggagtt ctaatatgaa attagctgtt ttcacagatt cctctgctta
     4621 tctcagtgaa gagaccttgc aaagagaaga cttgtttgtc ttggatattc ctgtcaatat
     4681 tgatggtgag gaatatgtcg aaggcatcaa tctgtctgct gaggaatttt accaaaaaat
     4741 ggctcaggct tctgaattgc ctaagaccag tcaaccaagt attgccaagt tagatgaaat
     4801 cttaacttcg ctcaaagaac aaggctatac acatgccttg gggcttttcc tatcttctgg
     4861 aatttcaggt ttttaccaaa atatccagta tatggtcgat gactatgagg gcttaaccat
     4921 tgctttccca gacactttga ttacaagtgc tcccctaggc atcatggttg aaagcgtctt
     4981 taattggcgt gatcagggcg atgattttgc cagcattcag gataagctag ccattcaaat
     5041 cagccgtacg tcagccttta tcatggtaga tgacttggat catttggtaa aaggtggacg
     5101 cctttcaaat ggggctgcca ttttgggcaa tttgcttagc attaagccaa tcctttattt
     5161 taacgatcaa ggtgtgattg aagtttacga aaaagttcgt actgaaaaga aggccaccaa
     5221 acgcttaatt gaaattatca aggaaacaac ggcttcaggt caataccggg tcattgtcat
     5281 tcatgggaat gctcctgaaa aggctgaaga attgcgtcag catttgcttg attttggctt
     5341 gggttcggat gtttcacttg ctacatttgg tagtgtcatt ggaacgcacc taggagcagg
     5401 aagtattgct ctaggttata ttccagtgat ttagttggca cttctaggct agttaatctt
     5461 agaaattgaa cacggactac ctgcctcttg aaaaaagatg cctgtcttgc ctttcgtgga
     5521 aagtcagtgc cattccctat ttttcagggg cagctaaggt cctttgtatc ttgataattg
     5581 aacacgcctg gaaccctgtg tgaaaaagat agttcttcca agaagtagac acttcttgat
     5641 tggaattcct attttcactt tgtgttctta cggactttgt atcttagaca ggagtagaga
     5701 tgagtattcg ggtaattatt gccggtttta agggaaagat gggccaggct gcttgtcaga
     5761 tggtattgac tgatccagac ttggacttgg tggcagtttt ggatcctttt gagtctgagt
     5821 cagaatggca gggtattcct gttttcaagg ataaggctga tttagctggt tttgaagcgg
     5881 atgtctgggt agattttact actccagctg ttgcctacga aaatacacgt tttgctcttg
     5941 aaaatggctt tgctccagta gttggaacga ctggtttcac gagtgaagaa attgcagagc
     6001 taaaagaatt ttctcgtgcc caagacttgg gtggcctgat tgcccctaac tttgccttgg
     6061 gtgctgtctt actcatgcaa tttgcgacgc aggctgccaa atatttccca aatgtggaga
     6121 ttattgagct ccatcatgac aagaaaaagg atgctccgag tggaacagcc attaaaacag
     6181 ctgagttgat ggcagaggtt cgagagtcca ttcagcaagg cgcagcagat gaggaagagc
     6241 tgattgctgg tgctcgtggt gctgactttg atggtatgcg catccactca gttcgtttgc
     6301 caggtttggt agcccatcag gaagtcatct ttggcaatca gggagaaggg ttgaccctcc
     6361 gtcatgactc ctatgatcgc atctccttca tgacaggagt caatttggga attaaagaag
     6421 ttgtcaagcg tcatgagctt gtctatggat tagaacactt attatgagat taacgcaaat
     6481 gccttctgaa tttcagaagg ctttaccagt attagaaaaa attaaagaag caggctttga
     6541 ggcttatttt gttgggggct ctgttcgaga tgcccttctc cataacccta tccacgatgt
     6601 ggatattgcg acgtcttctt atccagaaga gaccaagcag atttttccgc gaacagccga
     6661 tatcggaatc gagcatggaa ccgtcttggt cttagatggg gatgaggagt atgaggtaac
     6721 aacctttcgg acagaggatg tctatgtgga ctatcgcaga cccagtgcgg tttcctttgt
     6781 gcgctcgcta gaagaagacc tcaaacgccg tgatttcaca gtcaacgcct ttgccttgga
     6841 tgagacagga gaaatcgttg acttgttcca tggtttagaa gatttggaaa agcaagtctt
     6901 gcgagcagtt ggagtggcta gtgagcgttt caacgaagat gctttacgga ttatgcgtgg
     6961 tttccgtttt caggctagtc ttggttttgc acttgaacca gaaacattta aagctatgaa
     7021 gaccttgacg ccgcttttgg agaaaatttc tgtagagcgt accttcgtcg agtttgataa
     7081 actcttgctg gctccatttt ggagaagggg cttggcttcc atgattgaga gtcaagctta
     7141 tgactatctc cctgatatgg catctagcca ggacaagctc aacagactgt ttgatttgga
     7201 gactgatttt acttttgaat cctctgaaca agcctgggcg gctttactat gggctttgga
     7261 gattgaaaat gcgcagtcat ttttgaaatc ttggaagacc tcacgccagt ttgccaagca
     7321 agttcaggat ttgctgatta ttttggctct gcgtgaaaat ggagaattga gcaagcgaga
     7381 ttgttatcgc tttgacatag atttgctttt acaggctgaa aatcttcgtc aagctcaagg
     7441 aaaagaagtc aacccacaag ccatcacaga aaaataccaa agcttgacta tccatgacaa
     7501 gaaagagatt cagattaatg gcggtatttt gatcaaggaa tatggctatc agccaggccc
     7561 agacttggga gagattttaa cagagattga gtttgccatt gtcgatggag aattggagaa
     7621 taatcgtgaa gccatccatg cttacctgag ggagaaaaaa tgagtgattt tatcgttgaa
     7681 aaactaagta aatccgttgg tgacaagacc gtttttaggg atatttcctt tattatccat
     7741 gacttagaca gaattggttt aatcggtgtc aatgggactg gcaagaccac ccttttggac
     7801 gtcctttctg gtgtttctgg atttgatggg gatgtcagtc ctttttcagc taaaaatgat
     7861 taccagattg gttacttgac tcaggatcct gattttgatg atagaaagac agttttggat
     7921 acggttctat ctagtgaact caaggaaatc cagctcattc gtgagtatga attgattatg
     7981 ctcgactata gtgaggacaa gcaggcgcgt ttggaacgtg tcatggcaga gatggactct
     8041 ctccaagctt gggaaatcga aagtcaggtc aagaccgttc ttagcaaatt gggcattcaa
     8101 gacttatcta ctcctgttgg ggaattgtca ggtggtctga gaagacgggt acagttggca
     8161 caagtcttac ttggcaacca cgacctcttg cttttggatg agccgaccaa ccatctggat
     8221 attgcgatta ttgagtggct gaccctcttt ttgaaaaatt ctaagaagac cgtccttttt
     8281 atcactcacg atcgttattt cttagacgct ttgtcaacac ggattttcga gttggatcgt
     8341 gcaggcttga ccgagtacca gggaaattac caggactatg ttcgcctaaa ggcggaacag
     8401 gatgagcgcg acgcggctct tcttcacaaa aaagaacaac tctacaaaca agaattggcc
     8461 tggatgcgca gacaaccgca ggcgcgtgcg accaagcagc aggcccgtat caatcgattc
     8521 catgatctga aaaaggaagt ttcaggcagt agtgctgaga cagacttgac catgaacttt
     8581 gaaaccagtc ggattgggaa gaaagtcatc gagtttcagg ctgtttcctt tgcctatgaa
     8641 aacaagccta ttttgcaaga ttttaatctc ttggtgcagg ccaaagaccg tatcggaatc
     8701 gttggggaca atggtgttgg aaaatcaacc ctgctcaact tgattgcagg aagtcttgag
     8761 ccaactaaag gacaagttgt gattggggaa actgttcgca tcgcctattt ctctcagcaa
     8821 attgagggtt tggatgaaag caagagagtt atcaattacc tgcaggaagt ggcagaggag
     8881 gtcaagacca gtggcggttc tacgacttcg attgcagagt tgctggagca gttccttttc
     8941 ccacgttcga cgcatggaac cttgattgag aaattgtcag ggggtgagaa aaaacgtctt
     9001 tatctcctca aactgctttt ggaaaaacca aatgttcttc ttttagacga gccaaccaat
     9061 gacctagata ttgcaacttt gacagtctta gagaatttct tgcaaggttt tgcaggtccc
     9121 gttttaacag tcagtcacga ccgctatttc ttggataagg tagcgaccaa gattctcgct
     9181 tttgaggatg gcaagattcg tcctttcttt ggtcattaca ccgactatct tgatgaaaaa
     9241 gcttttgaaa cagatatggt caatcaagtg caaaaggtcg aaaaggaaaa agtggtcaag
     9301 gttcgagaag acaagaaacg catgacctac caagaaaagc aggagtgggc aagtattgaa
     9361 ggtgatattg aaaccttgga aaaacgtatc gctgctattg aagaggaaat gcaggctaac
     9421 ggctctgact ttggtaagct ggctactctc caaaaagaat tggatgagaa aaatgaagca
     9481 ctccttgaaa aatacgaacg ctatgagtat ctcagtgaat ttgatagtta agactattcg
     9541 aaaatcaaag tgcaaactat gtcggcttca cattgccgac tcaagtacag cctgtgaccg
     9601 gcttcctaat ttgcactttg atttttattg agtataaacg aatagaaaaa tcccgtctca
     9661 tgaaaggatt tctctattct tttttggttt cttgatgaaa gatattttgc caggtttcgt
     9721 ggcgacgcca gatactggta tggatgatac catctaactc atagcagata agtttggttt
     9781 tttgactgat ggaagtaatt tgaatgtcct tgatagcaga atttaactct tttttggtct
     9841 tataagcctc tttatccatc tgctctccat cttggcgaat atagacaaaa tcatcagtca
     9901 agagttcttc tagttggttt ccttggtcga tcaattgttc acgcataagc aattttttat
     9961 agacattgtc taaaatttca tcctcaggga taggtgctgg ttcgatatgg acatcggtat
    10021 caaagacgcc aaaacgattc tccagcatag actcgacctg atccgcgatt tcatggcttt
    10081 caaaaacaga caagtcagga ttcatctcta gtgtaatatc caggtagatg ttgctaccgt
    10141 aggtgcgacc tctttgcgat ttgaccttgc tgattttggg aatttccatg atagcctttt
    10201 ggtagtcctc gagcaggcgg tcgtcaaagc catctgaaag actaaaggaa gactcgatga
    10261 agatatcata ggcagtcttc aagataaaga aagtgatgat gatagcaacc agtttatcca
    10321 caatcggata attgaaacta ctagctagga tggcaatggc ggttccaagt gaggtaacag
    10381 cgtcagaaag attgtcctta gcagctgcct tcagcgcctt ggagttggat ttcttactga
    10441 ggcgagtatt gtagagatag accacaaaca taatcgctgc agaaatgatt cctagagttg
    10501 caccaagagg atcaatgacc gtttcttccc gactgagaat cttttgaatg gtatctctta
    10561 gaacatcgaa accgacatag aacatgatga tagaagtgat caagcttgcc aaatcttcaa
    10621 tcttccaatg accaaaacgg tggtcacggt ctgcaggctg gcgcgccatc cgaatcccga
    10681 ttaagagggc cacatttcca atgatgtccg atacgttatt aaaaccatcg gccaccaaac
    10741 tggatgaatg aaggagatga ccagctgcta atttggctgc agacaagatc aaataggtcg
    10801 aaatactgat aatggctcca cgctcagcta acttgagatt tgagatagat tgcttcattc
    10861 aacttccttt ctagtcacat agcattctac cattatactg gttttcaagg aaaaattcaa
    10921 ataaggcagt ttttactctt tgaaaactcc ccaaaatttg gtataatggt actactcaag
    10981 ggagtagctg gcagaaacct gtgatagtgt cgtcattccg aattttatgc tgaaaagtat
    11041 gctttccggc cctatcttaa acagcgagac ttgttatgat taacaggtct ctttttgttt
    11101 gtcgtgaaaa gatatgacag aaagagagtc tgttttgcac acaatgtcaa ggaggagaca
    11161 catgtcaaaa gaacaaaaac gccaagcgtt ttatactcag agccctgaag aggtcttgca
    11221 ggctgtggat gcgaccgagc aaggtttgtc atcaagtgag gcggaaaagc gccttgccga
    11281 atttgggcac aatgaactcg aagaaggcga gaaacgatca atcttggtca aattcatcga
    11341 gcaatttaag gatttgatga ttatcatcct agttgcggca gcaatcttgt cagtcgtgac
    11401 ttctggtggg gaagatatcg cagatgccat tatcatccta gctgtggtta tcatcaacgc
    11461 tgcctttggt gtttaccaag aaggaaaagc tgaagaagct attgaagccc tcaaatccat
    11521 gtctagtcca gttgcccgcg ttcttcgtga tggacacatg gcagagattg actctaaaga
    11581 attggtacca ggcgatatcg ttgcccttga agcaggtgac gtggtaccag cggacctacg
    11641 tttgatagaa gccaactctc ttaaaattga agaagcagcc ttgacaggtg aatctgtacc
    11701 agtcgaaaaa gacttgtcag tcgagcttgc gacagatgct ggtattggtg accgtgtcaa
    11761 catggccttc caaaactcaa acgtaaccta tggtcgtggg atgggtgttg ttgtcaatac
    11821 aggtatgtac actgaagttg gtcatattgc tggtatgctt caagatgcgg atgagactga
    11881 tacaccactc aaacaaaatt tgaacaacct ttctaaggtc ttgacctatg ctatcttggt
    11941 cattgccctt gttacttttg tagtgggtgt cttcattcaa gggaaaaatc cacttggtga
    12001 gttgttgact tctgttgccc ttgccgttgc agccattcca gaaggacttc ctgctatcgt
    12061 taccatcgtt ctttctcttg gtactcaagt tttggccaaa cgacattcta tcgttcgtaa
    12121 gttgccagca gttgaaacac ttggttcaac tgaaatcatc gcttctgata agactggtac
    12181 gctgactatg aacaagatga cagtcgaaaa agtcttctac gatgcggttc tacatgactc
    12241 agctgatgat attgaactag gtcttgaaat gccactactt cgttcagttg tcttggccaa
    12301 tgatacgaaa atcgatgtgg aaggtaactt gattggtgac ccaaccgaaa cagcctttat
    12361 ccaatatgcc ttggacaagg gctatgatgt caaaggtttc ttagagaaat atcctcgtgt
    12421 agctgaattg ccatttgact ctgaccgtaa gctcatgtca acagttcacc cattgccaga
    12481 tggtcgtttc cttgtagcag tcaagggtgc gccagaccaa ctcttaaaac gttgtcttct
    12541 tcgtgataag gctggggata ttgctccgat tgatgagaag gttacaaatc tcattcatac
    12601 aaacaactct gaaatggctc atcaagcctt gcgtgtcctt gcaggtgctt ataagattat
    12661 tgacagcatt ccagaaaatc tcacttctga agagcttgaa aatgatttaa tttttactgg
    12721 tttgattggg atgattgacc ctgaacgtcc tgaagccgct gaggctgttc gtgtggctaa
    12781 ggaagcggga atccgtccaa ttatgattac aggtgaccac caagacacag cggaagccat
    12841 tgccaaacgt ttgggaatca ttgacgcaaa cgatacagaa ggtcacgttt taactggtgc
    12901 tgaactcaat gaactgtcag atgaagaatt tgaaaaagtt gttggtcaat actctgttta
    12961 tgcccgtgtg tctccagaac acaaggttcg tatcgtcaag gcttggcaaa aacaaggtaa
    13021 agtcgttgcc atgacaggtg acggtgtcaa tgacgcgcca gctctgaaaa cagccgatat
    13081 cggtatcggt atgggaatca ctggtacaga ggtttctaag ggggcttctg atatgattct
    13141 tgcagatgat aactttgcga ctattatcgt cgcagtggaa gaaggacgta aggtcttctc
    13201 aaacattcaa aagactattc agtacctact ttctgctaat actgctgaag tattaaccat
    13261 cttcctatca accttgtttg gttgggatgt cttacagccg gttcatcttt tgtggatcaa
    13321 cttggtaacg gataccttcc cagctatcgc tcttggtgtt gaacctgcgg aacctggtgt
    13381 catgaatcat aaaccacgtg gacgcaaggc aagcttcttc tcaggtggtg ttttgagttc
    13441 tatcatttat caaggtgtac tccaagcagc tcttgttatg agtgtttatg gccttgcgat
    13501 tgcttaccca gttcatgtgg gtgacaatca tgctattcat gcagatgccc taacgatggc
    13561 ctttgcaacc cttggtttga ttcagctctt ccatgcctac aatgtcaagt ctgtctacca
    13621 atccatcttg acagttggcc cattcaagtc taagaccttt aactggtcca tcttggtatc
    13681 ctttatcctt ctcatggcaa caatcgttgt agaaccgctt gaaggaatct tccacgtaac
    13741 caaactagac ttgtcacaat ggggaattgt tatggctgga agcttctcaa tgattatcat
    13801 cgtcgaaatc gttaagttta ttcaacgcaa actcggtttt gacaagaatg cgatttaagg
    13861 gaggtctcgg atgtcagcat atcaattacc gaccgtatgg caggatgaag ctagtaatca
    13921 aggagctttt acggggctaa acagaccaac agcaggtgcc cgtttcgaac aaaacttgcc
    13981 aaaaggagaa caagcttttc agctttattc actgggaaca ccaaatggtg tgaaggttac
    14041 tatcttattg gaagaattac tagaagctgg ttttaaggaa gcggcttacg acttgtataa
    14101 gattgctatc atggatgggg atcaattcgg atcagacttt gtgaagctca atccaaattc
    14161 caagattcca gccttattgg accagtcagg tactgaagat gtaagagtct ttgagtctgc
    14221 tcatattctt ctttaccttg ctgagaaatt tggagccttt ttaccaagta atcctgtgga
    14281 aaaggtagaa gttttgaatt ggctattctg gcaagcaggt gcagcacctt ttctaggtgg
    14341 gggatttgga catttcttca attatgctcc tgaaaaattg gaatatccta ttaaccgttt
    14401 tacgatggaa gtgaaacgcc agttggattt attggataag gaattggctc agaaacctta
    14461 tattgcaggc aatgactata cgattgcaga tattgctatc tggtcttggt atggacagtt
    14521 agttcaagga aatctttacc aaggttctgc aaaattcttg gatgcctcaa gttatcaaaa
    14581 tctagtaaaa tgggcagaaa aaattgccaa tcgtccagct gttaagcgtg gcttggaagt
    14641 aacttataca gaaattaaat agcaaaaaag tcatcttcgg atggcttttt gctacagttg
    14701 agggaaaggg tttgcagtta tcggcttttg tgctataatt gctataatat agtaaaaagc
    14761 aagaggagtg tgaggaagtg gaaaagaaaa ttgtgaagga tatcttattt ttatctcaag
    14821 tgtctcagcc ggcaagtcag gaggaccttt atcttgccag agatttgcag gatacactct
    14881 tagcaaatcg tgatacctgt gttggtctag ctgccaatat gattggggtg cagaagcgcg
    14941 tgattatctt taatcttggc ttggttcccg tggtcatgtt taacccagtg cttctgtcct
    15001 ttgaaggatc ctatgaggca gaagaaggct gtttgtcctt ggtaggtgtg agatcaacta
    15061 agcgttatga aaccacaagg cttgcctatc gtgacagcaa gtggcaggaa cagaccatta
    15121 ccttgacagg cttcccagct cagatttgcc agcatgagct ggatcacttg gaaggacgaa
    15181 tcatttagga ggaaagcaaa tgaaacgaat agtctgtgaa cttattttta tcgcaacgac
    15241 ctggtatatc tttttaccgc cccttaacct gaccagctgg gaatttctct tcttcctctg
    15301 tgggcatttg ttagttgtgg caatcttatt tggctttggc aaggggataa accttgtcaa
    15361 aacggttcat gtgcgccacg gtaaggcgga agctgcctta aatcttgagg gtttcaaaat
    15421 caatcggtta gggaaaattc tgttagcttc gattggagga attcttctct tggcagcttt
    15481 ggtttccttg gtaacttcca gcatgtttca ggctaaaaat tatgccaatg tagtcacggt
    15541 tacggaaaaa gactttactg aatttcctag gagtgacacc agtaaggttc ctatcctaga
    15601 tagaagtact gctgaaaaaa ttggagaccg ctacttgggt tccctaaccg ataaggtgtc
    15661 gcaatacgta gcggcagata cctataccca attgacaatt gatgggaaac cttatcgggt
    15721 cacaccacta gaatatgcag accctatcaa atggtttaac aatcaagcca agggaatcgg
    15781 tgagtatatc aaggtggaca tggtaactgg aaatgcggat ttggtggact tgaagacacc
    15841 aatcaagtat tcagactcgg agtattttaa ccgtgatgtc aaacgtcacc tgcgcttgaa
    15901 gtacccgact aaaatcttta aaactccatc ttttgaggtg gacgatgagg gcaatccttt
    15961 ctatgtagca acggtttacc aaaagcaatt tggacttgcg gttcctcgtc ctgcttcagt
    16021 cattatcttg gatgctacaa atggagaaac caaggaatac agcttatcag atgttccaga
    16081 atgggtggac aggatctatc cagcagagga aaccattgag caaatcaact acaacggcaa
    16141 gtacaaggac ggtttcttga atgccatgat ttccaagaaa aacgtgaccc agactaccaa
    16201 tggctataat tacttgtcta tcggtaatga catctatctc tacacaggtg tgacgtcggc
    16261 taatgcggat gagagtaatc ttggtttcat ccttgaaaat atgcgaacag gagaaattac
    16321 taagtatagc ttggcttctg cgacagaaga atcagcccgt gaatcagcag aaggtgctgt
    16381 tcaggagaaa tcctacaaag caaccttccc aatcctcatc aacctcaatg acaagcctct
    16441 ctacatcatg ggcttaaagg acaatgctgg cttggtcaaa gagtacgccc tggtagacgc
    16501 agtcgagtac caaaatgtta tcgttgctac tacagtggaa gagatgctca gcaagtatgc
    16561 caataaaaac gaccttgaaa ttgacaatgc aacgacagaa agcatcaagg gagtagtagc
    16621 agacctcaaa tcagctgtta tcaagggaga cactgtctac ttctttaaag ttgatggcaa
    16681 gatatacaag gtcaaggctt cagtatccga tgaccttcct taccttgaaa atggtaaaac
    16741 cttcgaaggt caagtaggaa aagacaatta tctcaagacc tttaaagtac aataatactc
    16801 ttcgaaaatc tcttcaaact acgtcagctc tatctgcaac ctcaaaacag tgttttgagc
    16861 agcctgcggc tagtttccta gtttgctctt tgattttcat tgagtataaa aaaggtttat
    16921 ttaagaaata tatgttataa taaggtaaat taagcctaat ggaggacaaa gaaatgggtt
    16981 tttatttgat ggttgcttca atgctactcg gactgctcgc tttgaagata ggtttttctc
    17041 agttcaagga gaaaaaagat aaattcttat ctatcttaac aagtttagct ggcatagccc
    17101 ttgttctcgc ggctgtctgg ttaggatggc ccaaataaat agaaaaacct cggtcaaacc
    17161 gaggtttttc aaatgaattt cttggttgtg gctaaaaaat atgctacact atcaatatga
    17221 aaattttaat cccaacagca aaagaaatga acacagactt gccaagtatc gaggcaattc
    17281 ctttaaaacc agaaagtcag accgtgcttg atgccttggc tctctattct gccagtcaat
    17341 tggagagttt ctacaaggta tcagctgaga aagcggcgga agaatttcaa aatatccaag
    17401 ctttgaaaag gcaaactgct caacactatc cagccttgaa actttttgat gggcttatgt
    17461 accgcaacat taagagagat aagctgaccg aggcggaaca agattatctt gaaaatcatg
    17521 tcttcattac ctcggctttg tacggtgttg ttccagcctt gtcacccatg gctcctcacc
    17581 gtttggattt tttgatgaaa ttaaaagtcg ctggtaagac tttgaagagc cattggaagg
    17641 cagtctatga tgaagctctg aagaaggaag aagtgatttt ctctctcttg tcatcagagt
    17701 ttgagactgt attttctaag gaaatcagag caaagatggt gaccttcaaa ttcatggagg
    17761 atagaggcgg tcagctgaag attcactcaa ctatctccaa gaaagcgcgc ggggcctttc
    17821 taacagcttt aatagaaaat caagtacaaa ctgtggggga agcacgtcgc ttgaactttg
    17881 ctggatttgt ttaccgagaa gatttgtcac aaccacaggg attggttttt gtaaaggaag
    17941 tatagaaatc agataagaga aaagtcagca cgattatgct gacttttttg ataacttata
    18001 aagtattgga caaatgaatc tcatttgata aggtgttaag atgattaacc aaattcatga
    18061 ttgacagatg atttcggcaa ataaacttct tggtaatccc tggaatatag aaattagaca
    18121 cgatgatatc gtaatctgtc tgatttaaaa tctcaggact tgtttttaat tcatcccaaa
    18181 tatcgaaggt aaagcggtta ttacagtaat aggaaagcat atcaacaaag gtaagggata
    18241 tagcatggtc aaagttactg ataatcaaaa ccttgatagg tggtcgattt tctaacaact
    18301 gagtagagag gttttcagca tgggttaaga tggtgtacat caagtgttcc aactgttcag
    18361 gatggtcatg ctgtccaatt gcctgacggt attgagccaa ttcttgacgc gcacttccca
    18421 taaagtctgg gaagtaaact tcaaattttt taatcgtcaa tgctttttgt tcaaataaga
    18481 ttggggtaga aaagatttcc tgtctttcaa agaaagcagt gttgtgtaaa tgccaaatca
    18541 gctcatcgtg gttagtaaaa gtaatcttat attgttttga taggccttct aatatttgac
    18601 taagtaattg gtaagagtat cttgcttgac tgttatcttc taaagagttg aagaattctt
    18661 gaggatctag gaaaatatca ttctgaagaa aagaaataaa aatttgagcg attgtatctg
    18721 gagtcatttc aagcccaaaa tgtttagaga aataagcaag tgtctcctgg aaattcggaa
    18781 tgctctttaa aagaggataa tattctttgt aaaagtggtt ggggaggtca atgaagtgac
    18841 catttttaac cctgtggata ctgatagcta tcatcagttt gtacattcta taaattgaaa
    18901 atcgcattgg ataatttgtg attttataga agaagtcagc aaactctgtt aaatcttcct
    18961 caggaaggtc aggaaaaggc caatctagga aataatagcg ctcagaaaag tattgggcaa
    19021 aaaagtaacg aatatcgatc tcatttccac gtatctcgga tggagtaaaa gataattcaa
    19081 tttgaaactg agatgaaaga acctttgtaa tatttctgcc cagtcgatag aggttggcac
    19141 tactaaagta aagattttct attgttcgat aaataggtag cccctcattg aagaacatat
    19201 actctagtaa ttgaaaagat tgagaattag caagaaagta ttgataaata tcttctacac
    19261 tagtgttaac ttctaaatct atcatgattc cgttaacaga agattggatg ttaatagatg
    19321 gaaaggcaat acgtaattca tttaaatcac tttttaagat tcgttctgta catcctaatt
    19381 tttcggctag ttcatgtaat ttcatccaat tacgattctg aattagggtt tccattaagc
    19441 gtaattgtct ttgaactttt gtggataaaa ggtttctcat acgggtattt cctccataat
    19501 tcattatatc tttttttgtc taagtagtat aaaaaaatta gagcaagaaa attgtcgtta
    19561 gtaatcggaa aaattagaat aatataagtg gcttttaagt gcaaaaacag aatatattaa
    19621 ttgttcagaa aatattgatt aatgcctcaa atagttgtac attgtaaact ataaaatact
    19681 atctaggagt ttaaaatgaa acattcacat aaaaaatcat ttgactggta tagcatgcaa
    19741 caacgttatt ctattcgtaa gtattacttt ggtgcagtta gtgtcttgct cggtaccgct
    19801 ttggtattag gtgcagcagc tagtgtccaa acagtacaag cggaagaaaa caaacaagaa
    19861 actaccaata gtatttctgt tggtagggga gaagcagcta ctaaactagc agaggtttct
    19921 gcgtctaata aagagaaaac ctatgcagct ccaactgtag ctaatccagt agaaacgact
    19981 ccagttaaaa ctggagaagt tactaaacca gcagaaaaag ttgaagaagc aaaagacaaa
    20041 aaagaggaag taacgcatca agatgctatt gacaagtcaa aattgttaac ggctctttcg
    20101 cgtgctaaaa agttagaaag caagttatat acagaagcaa gtgctgctaa cttgcaaaca
    20161 agtatccaag ctggtcaaag cttgcttggg aaagcagatg catctgaagc tgaattatca
    20221 gcagcagagt catctattca atcatctatt attggtctag aacttcgttc taactctaac
    20281 aaaggaactg tatcagaaac tcctgtagcg aagaaagcta atatagttga agcgaaggaa
    20341 gagactaatc cagctgcaac aactgatcgt tcagctgttg atagtgctgt tttgccaact
    20401 agcacagctg ccaaagtaga aacaacttca gctccagcat ctattaatga aatcttgaaa
    20461 ccaggtttga gcctttctga tgctcgccaa aatccagcta tccgtaaaga agacttggat
    20521 aaggggtata gtggttttag agcagcacct gctccaacga acaaactagt aactaatcta
    20581 ggaaataata ctgttttcac tgatattagc agagggtctc atactttccg tggtaatggg
    20641 aattcacgtg gtggaaaccc gattcatttt gatgtaacaa caactagagt tggaaataga
    20701 gtagaattct caattgcata ttctggtcca ggtgagttcg ttaataataa ctttctctta
    20761 gacaaaggga atggatttgg agaaccatct cgtgcaacta tttcaacaaa cagattaaga
    20821 gatcaaacta aagatataag aaagggtgca aattttgtat ctcattcaag ctacagttta
    20881 acatctgctg ttgaaacaaa cagtaatcaa actattagat ttagtttacc tatagccaac
    20941 cctaatggtg atctgtctgt tcgattaaga cctgttactt ttaatgtagg tcaaggggaa
    21001 tcaggatctg caactagtaa tgatccatat agtaactcta actattactt cagagaaaaa
    21061 ccactcctct tggatgcaaa tccaaatggt ggtactaata ataagactgt ttcagaagac
    21121 attgacttcc aaactgtcta tcttccaact agtaagttac cagaaggtca aactagatta
    21181 gttcgagaag gtgaaaaagg acaacgtcaa atcatctata aagttcatca attgggtaac
    21241 gaaacaatcc taggattgcc aattagtaat tcagttatta aagaagttaa gccacgtatt
    21301 atgcaaattg gtgtggctaa agatctaatc gatacagtaa aaccacgtgt tgatcaaaat
    21361 aaagtcggtg atacaaataa cctcactttc tatcttgata acgatggaaa cggtgtttat
    21421 actgagggcg tagacgaact tgttcaaaaa attgctatta aagatggtgc taaaggtgaa
    21481 aaaggagtcc aaggcgaacg cggcctgact ggagcgcaag gtcaggcagg tcgtgacggt
    21541 gtaactccaa ccgtaaccgt taaagataat aaaaatgacg gcactcatac tatcactatt
    21601 aacgacggta gaggtaatgt tgcaagtact gttgtaagag atggtttcga tggcgcaagt
    21661 ccattagttg cgactcaacg aaatgaagca gataagacaa caactgttat cttctattat
    21721 gatcaaaatg gaaataatga attagatgct tctgataaga aattaaaaga agttattatt
    21781 gcagatggtg ccaaaggtga acaaggtctt caaggtcgtg atggagctca aggaccaaaa
    21841 ggcgcagatg gacaaagagg accagcggga ccacaaggac caaaaggaga acaaggtaat
    21901 ccaggaactc caggtaaaga tggaaaatct ctaattgctg ttaaaaatgg aactgaaaca
    21961 aaagtctatg tagaggatcc ggctagacca ggacaaccac ttaatccaaa ccaaccatta
    22021 gcaactatca ctgatggaag aaatggtact aatggacaat caccaacaat tacagcgaca
    22081 cgaagtgttc aaaatggtaa aaatggtgta ttagtaacaa ttacaccagt aggaggtcgt
    22141 ccacaaacaa catttgtaga ggatggacaa aaaggtgctg atgggaaaac cccaacagta
    22201 acaataactg aggggcaaaa cggcacacat acattaacgg ttcataatcc aggaagtcca
    22261 gatgtgacaa ctacgatccg tgatggagct acaggacaag caggtcgtga tggtaaagat
    22321 gtattaaacg gaaaagtaaa tccacaacca aaccaaggta aaaatggaga taaatatatt
    22381 aataccgaaa ccggtgatgt ctatgttaaa aacaatggaa actgggataa agaaggcaac
    22441 atcaaaggcc ctaaagggga caaaggtgca gatggtgcta aaggcgaaaa aggagaccaa
    22501 ggcgaacgcg gcctaactgg agcgcaagga gctaaaggtg cggatggcgc agtaggtcgt
    22561 gatggacgtg acggtaaaga cgtgttgaac ggcaaagcta acccagaagc acatcaaggt
    22621 aaagacggcg ataaatacgt taatacagaa acaggcgacg tcttcgttaa gaataacggc
    22681 aactgggata aagagggcaa catcaaaggc cctaagggtg acaaaggtga acgcggagaa
    22741 gatggtaaga ctccagaagt aactgtaact ccaggtaaag atggccatag tactgacatt
    22801 acattcactg ttccaggtaa agatccagtt acagtaaatg ttaaggacgg agaaaatggt
    22861 ctgaacggta aaactccaaa agttgattta cttcgtgtcc aaggaaaaaa cggaaatcca
    22921 tctcatacaa ttgtgacatt ctatacagat gaaaacaatg acggcaaata tacaccagga
    22981 actgatgaac ttctaggttc agaaatgatt aaagatggtg ctaaaggcgc ggacggacga
    23041 gatggtaaat cattgcttac tgtcaaggat ggtaaagaaa ctaaagttta ccaagaagat
    23101 ccagctaacc caggacaacc attaaatcca gaaaaaccac ttgcggtaat tagagatgga
    23161 gtagatggaa aatcacctac agttacagct gttcgtaaag atgaagcagg gcataaaggt
    23221 gtagaaatca ctgttgataa ccatgatggt tcacaaccaa ctacagtctt tgttcaagat
    23281 ggtgctaagg gagaaactgg tgcaaccggt caggatggac aaactcctac aatcactact
    23341 caacgtggac aagatggcca aagcactgtt gtaactatca caacatcagg taaagatcca
    23401 gtaaccttca ctgtaaaaga tggtaagaat ggtaaagatg gccgtgcacc gaaaatcaaa
    23461 gtagaagata ttacttcacc ttcaagaatt agacgcgata cagatgctgc tgcaactcca
    23521 acgcgtaacg gtatccgtgt tacagtttat gatgatgtta atgacaatgg ggtatacgac
    23581 ggaggtgtcg ataaagtatt aaatagtaaa gatatttata acggtataga tggacgtgat
    23641 ggttcagctc caactattac tacaaaagat aatggagatg gaacacacac tatcacagtt
    23701 caaaatcctg atggttctga atcaacaact gttgttaaag atggtaaaga cggtaaaact
    23761 gcgaatatca ctacaacaga aaacccagat ggaagccaca caattacggt gacaaatcca
    23821 gatggttcaa ctaaagaaac tgttgttaaa aacggtaaag acggtaagac tcctaaagtt
    23881 gaagtaacgg ataacaacga tggaacacac acagttaaag tgacggatgg agacggcaat
    23941 gttaccaacg ctatcatcaa agatggtaaa gatggtaaag ctgcaacagc aacaactact
    24001 gaaaatccag atggaagcca cacagtaaca atcactaacc cagacggaac taagaatgag
    24061 tttgttgtta agaatggacg tgacggtgtt gacggacgta ctccaaccgc atctgttcgt
    24121 gataatggag acggaagtca tacaatcgtt attacaaatc cagaaggtgt gacaactgaa
    24181 accacagttc gtgatggtaa atcaccaaaa gtgactataa ctgatgaaca aaatggaact
    24241 cataagatct ctgttctaaa tggtgacgga acaactactg aaacaatcat tacagatggt
    24301 aaatcaccag tagcaacagt tagagataac caagatggta cttacactat tcgtgtggaa
    24361 aacggtaatg gtactgtttc tgaaaccaca gttcgtgacg gtaaatcacc aactgctaag
    24421 gttgtggata atggagatgg aactcacact atcacagttg tgaactcaga cggaacaact
    24481 acaacaacta cagttcgtga tggtagagaa ccaaaacttg aagttattga taacaacgat
    24541 ggttcacaca ctattaaagt gacaggtgct gatggtaaag gaacgacaac tacaatcttt
    24601 gatggtaaat caccaaaagc gaacatcgtt gataacggag atggaactca tacattaaca
    24661 atcgtagatt ctgatggtcg tgaatacaaa tctattatca aagatggtaa agacggcaaa
    24721 gatagcgttt caccaactgt aactgttaaa aataataacg atggaactca cgttgttaca
    24781 atcactaatc cagatggaag taagacagaa atggtgatta aagacggtaa agatggtaaa
    24841 tcaccaaaag tttctgttga agataatggt gatggtagtc atacaatcac aatcatcaat
    24901 tctgatggaa ctgtgacaaa aacagttatt aaagatggca aagatggtag agatggacgt
    24961 gatggtcgag acggcaaaga cggtaaagat ggaaaatgtg gatgccaaga caaaccagta
    25021 acaccatcaa atgacaaacc agttcctcca acaccaaatg tgccgacacc agaagtaccg
    25081 gttaaaccag taccagcggt tccagaacaa ccagtagtac caacaccggc tcaaccagca
    25141 actccagtaa atgctaaccc agtagcacca actacaggta aagaaaaccg tggggacaaa
    25201 ttacctgaaa ctggaagcca atctgattat atctctgttc ttttaggtag cggtattcta
    25261 ttgagcctat atgtaggacg aagaaaagaa gattaatcag ccaaaagcag tcactaattt
    25321 ctcgaaagaa gatgataagt gatagatctc gaatgaaaga atattcttag aatgattttc
    25381 ctatgatgga aaagactgct aaaaaccttg agtggtaacg ctcaaggttt ttttggatgg
    25441 ctgatgtttg tctgaaaatc ttgattgaga aataaaaagc caccctatta ggtggctata
    25501 attgatttag actttctaaa attttctatt ttttactgaa tcgcttcgac caagtcttga
    25561 gcttgttttt caagtgagtt taggactgtt tcttcaagaa ccaattttcc gtctgcccag
    25621 gcagagtcat taacacgtgc agcagtgaaa tcaccaacgc cttgtgtacg gataaatggc
    25681 aagaggtctt tgtagatagc gaaaagttga tcgtgccctg cattggctac agatgatact
    25741 gtgacaaact tgtcttgaag ggcagaaacg ccacgtgtat cagacaagtc aagggcacga
    25801 gatagccagt caagcaagtt tttcactgta ccagggatag agaagttgta gactggagag
    25861 aaaatccaga tagcatccgc aacgagaact gcttcacgag cggcagctac agctggatgt
    25921 gttgggactt ccaaatcttg gctgaagaga ggaagggctg aataatcaag gtagctaact
    25981 tccgctttac tagcaagtgc tttctcagct tcgagcgcca tttggtggtt gaaagaacct
    26041 tgacgtagtg atccgacgat aaataatact tttttagaca tgatgtgtct cctttttctt
    26101 aaaatttcga gaactctctc gttgttataa aatatattac aacaaaacaa aagaacttgc
    26161 aagaaatttg ctcagagttt atttgaaaat tgtaaaattt cggaaactct aatcatttgt
    26221 gactgaaaaa gtaagaactg tttcacttta aaaatcggtt ttgtttgaag ggagaaatag
    26281 aattggttgc tcaaagcaca gctttgaggt tgcagataaa gctgacgtgg tttgaagaga
    26341 ttttcgaaga gtattcttat attcacttgt aataaagctt aatagatggt aaaatagacg
    26401 agtgaaaaaa agacaaaaca aagcaaaaaa taatctactg tggcagtatg gtctagggat
    26461 gacgattttg tttgtggtta tcagtgcttc ctttctgtat atggtttctc ttagcatgaa
    26521 accctatcaa acagctaaaa gtgaaggaga aaaattagct cagcagtatg caggattaga
    26581 gcaggtcgat caggttgatt tatacaatgg cttggaatct tattacagcg ttcttggtcg
    26641 taataaacag caagaagcgc ttgctgtcct gattggtaaa gatgatcata agatttacgt
    26701 ttatcagcta aatcagggtg tttcacaaga aaaagcagaa acggtttcta aggaaaaggg
    26761 agctggcgaa attgacaaga ttatctttgg tcgttatcaa gataagccaa tctgggaagt
    26821 caagtcagga tctgattttt atctagtaga ttttgaaaca ggagcattgg tcaacaagga
    26881 gggcctatga aattatccaa ccgtgtttta gaaatggaag aaagtgtgac tttggctgct
    26941 ggagcccgtg ccaaagcact gaaggctgag ggtagagata ttttgtctct aaccttgggt
    27001 gagccagatt tcactactcc caaaaatatc caagatgccg ccattgcatc gattcgagat
    27061 gggcgtgctt ctttttatac agtaacctca ggtctgccag agcttaaggc ggtggtcaat
    27121 agctactttg agcgctttta cggctattct gtagcgtcaa atcaagtgac agtcgctgcg
    27181 ggagccaaat attctctcta taccttcttt atggctgtgg tcaatccagg tgatgaagtc
    27241 atcatcccaa ccccatactg ggttagctat ggagatcagg tcaagatggc agaaggcgtt
    27301 cccgtctttg tttctgctaa ggaagacaat cactttaagg tgaccgtaga gcagttagaa
    27361 gtagctcgca ctgacaagac caaggttttg gtgctgaatt cgccatctaa tcccacaggt
    27421 atgatttaca cccgtgagga actcttggca attggaaact gggctgtaga aaatgatatt
    27481 ctcatcctag cagacgatat ctatggccgc ttggtttata atggtcatga gttcacaccg
    27541 atttctagcc tatcggaagc gattcgcaag caaacagtgg tcatcaatgg tgtgtctaaa
    27601 acctatgcca tgactggttg gcggattggt tatgccgttg gagaagcaga cattatcgct
    27661 gccatgtcca agattgcagg tcaaacaact tcgaatccgt cagcagtagc ccaatatgca
    27721 gcagttgagg ctctatcagg tgagcaagat actgtagaaa gcatgcgtca ggcctttgag
    27781 gaacgtctta ataccatcta tcccctcctt gcagaggtgc caggatttga agtggtcaaa
    27841 ccgcaagggg ccttctatct cttcccaaat gtcaaaaagg ccatggagat gaaaggctac
    27901 acggatgtga cagactttac aactgctatc ttagaagaat ccgaagtggc cttggtaaca
    27961 ggagctggat ttggagcacc agaaaatgtc cgcctcagct atgcgacaga cctagacacg
    28021 cttaaagaag cagtcgaacg cttgaaagca tttatgggta gtgagaatga ttgatcattt
    28081 tgagattaag gtaaaggatt tacaaatttc agaaggattt tataggagtt ttctcgctcc
    28141 tttggactat aaattggctt ttaagactag ttctctaatt agttttctat ccccgaacag
    28201 ccctcatcct ggtggtgatt tttggctgac tcagggaaca caagatcctg ttcattttgc
    28261 ttttttagca gaaaataagg aagaagttta ggcttgttat gaggctggct tagaggcagg
    28321 tgggcgagac aatggggctc ctggttatcg aagtgagcgt ccgatttact atgctgcttt
    28381 tatgattgac ctggatggga acaatataga ggtggtttgc cataaagaat aaaaaagaaa
    28441 aggaaaaata atgacaaaac gtgtaacgat tattgacgta aaagactatg ttggtcagga
    28501 agtgacgatt ggcgcttggg ttgccaataa atcaggaaaa gggaaaatcg ctttcttaca
    28561 attgcgtgat ggaacagcct tctttcaagg tgtggctttt aaaccaaact ttgtcgaaaa
    28621 atttggtgaa gaagtgggac ttgagaagtt tgatgttatc aaacgcttga gccaagaaac
    28681 gtctgtttat gtgacaggta ttgtcaaaga ggacgaacgt tctaaatttg gctatgagtt
    28741 ggacatcaca gacatcgaag tgatcggtga atctcaagac tacccaatca caccaaaaga
    28801 acacggaaca gactttttga tggataaccg tcacttgtgg ctacgctctc gtaagcaagt
    28861 agctgtgttg caaatccgta acgctattat ctatgcaact tatgagttct ttgacaagaa
    28921 cggttttatg aagtttgaca gcccaattct ttcaggaaat gcggcagaag attctacaga
    28981 actctttgaa actgactact tcggaacgcc agcctacttg agccaatcag gtcaacttta
    29041 cctagaagca ggggctatgg ctcttggtcg tgtctttgac tttggtccag ttttccgtgc
    29101 tgaaaaatca aaaacacgcc gtcacttgac tgagttctgg atgatggatg ctgagtactc
    29161 atacttgaca catgatgagt cgcttgactt gcaagaagct tatgtgaaag ctcttctaca
    29221 aggtgttctt gaccgcgcgc ctcaagcctt ggaaaccttg gaacgtgata cagaactctt
    29281 gaaacgctac attgcagagc cattcaaacg tatcacttac gatcaagcca ttgacctctt
    29341 gcaagagcat gaaaatgatg aagatgctga ctacgagcat cttgagcatg gtgatgactt
    29401 tgggtcacca cacgaaactt ggatttcaaa ccactttggt gtgccaacat ttgtcatgaa
    29461 ctatccagca gccatcaagg ccttctacat gaaaccagtt cctggaaatc cagagcgcgt
    29521 gctttgtgca gacttgcttg ctccagaagg ctatggagaa attatcggtg ggtctatgcg
    29581 tgaggaagat tacgatgccc ttgtcgctaa gatggatgaa cttggcatgg atcgtacaga
    29641 atatgaattc taccttgacc ttcgtaaata cggtacagtt ccacacggag gatttggtat
    29701 cggtatcgaa cgtatggtaa ccttcgcagc aggaacaaaa catatccgtg aagctattcc
    29761 attcccacgt atgttgcacc gtatcaaacc ataagaacag gaaaacgccc atgtggcgtt
    29821 ttttcgaatt ctagtgtttt tacttgcgta aaaaaatttt ttctagtata atagtttatt
    29881 gtgagcgaac ctcacttacc ccttgcaaag tcttggggtc attagaccaa aaggaggaac
    29941 atatcaatgg ctaaatacga aattctttat atcattcgtc caaacattga agaagaagct
    30001 aaaaacgctt tggtagcacg ttttgactct attttgactg acaacggtgc aactgttgtt
    30061 gaatcaaaaa cttgggaaaa acgtcgtctt gcatacgaaa tccaagattt ccgtgaagga
    30121 ctttaccaca tcgttaacgt tgaagcaaat gacgatgcag ctcttaaaga gtttgaccgt
    30181 ctttcaaaaa tcaacgctga cattcttcgt cacatgatcg tcaaaattga cgcgtaagaa
    30241 ggtaaactat gattaacaat gttgtacttg tagggcgtat gacacgtgac gctgagttgc
    30301 gttatacccc atcaaatgta gcagttgcga cttttactct tgcagtaaac cgtacattta
    30361 agagtcaaaa tggtgaacgt gaggctgatt ttatcaatgt cgttatgtgg cgccaacagg
    30421 ctgaaaatct tgctaactgg gctaaaaaag gctcacttat cggggtgaca ggtcgtatcc
    30481 agactcgtag ttacgataac cagcaaggac aacgtgtcta cgtgacagag gtcgtggctg
    30541 agaatttcca aatgttggaa agccgtagtg tgcgtgaggg tcacacaggt ggagcttact
    30601 ctgcaccaac tgcaaactat tcagcaccta caaattcagt accagacttt tcacgtaatg
    30661 aaaatccatt tggagcaaca aacccattgg atatttcaga tgatgattta ccattctaat
    30721 ggacaactaa acttataaag gagaaaaaac atggctcaac aacgtcgtgg cggattcaaa
    30781 cgccgtaaaa aagttgatta catcgcagca aataaaattg aatatgttga ttacaaagat
    30841 actgagcttc ttagccgttt cgtttcagaa cgtgggaaaa tccttcctcg tcgtgtaaca
    30901 ggaacttcag ctaaaaacca acgtaaagta acaacagcta tcaaacgcgc tcgcgtaatg
    30961 gctttgatgc ctttcgtaaa cgaagattaa agaaaagacc cggttgggtc tctttttcat
    31021 gagcttgaaa acaagaaagc gaattaagac cccaacgggt cttttttcac aagctttgaa
    31081 atgagagagc gagttaggct cagtggctcc ctttttacga gtttgaaaac aagagaacac
    31141 attacaagca cgatggagct ttttcataaa tatgtctctt ttctcatcca agaaattaaa
    31201 ataaaaatga taaacttttt gaaaataggg gatttgccta ctttatgata taatggaaag
    31261 agttagattg aaagaggtag tgagatggac gcgaaattaa gatacaaggc aaagaagatc
    31321 aagattgtct tttttgatat tgatgataca ttgcggaatt caaagacagg gtttattcca
    31381 actacaattc ccactgtttt taaacagttg cgtgaaaaag gaattttaac aggaatcgcc
    31441 tctggacgtg gcatttttgg tgttgttcca gagattcgtg atctcaagcc tgactttttt
    31501 gtaactttga atggggctta tatcgaagat aaaaaaggtc aggtcattta tcagcatcag
    31561 attggaaagt cagatgttga ggagtatatc tcttgggcta agcaagaagg aattgagtat
    31621 ggcttggttg ggagtcatga tgccaagttg tcgactcgca ccgatatgat gagtgaagct
    31681 atcaatccaa tttatcccga cttagatgta gatcccgatt tccatgaaaa agaagatatc
    31741 tatcagatgt ggacttttga agataaggga gatgacttgc acttgcctga cagtctctca
    31801 gacaaacttc gcatggttcg ttggcatcaa cattcctctg atattgtgcc gatttcaggc
    31861 tccaaagcga cgggggtgga aaaggttgtg gaacaccttg gcttgaaacc agagaaggtc
    31921 atggtttttg gagatggtct caacgacttg gaactctttg attatgctgg aatcagcgtt
    31981 gccatgggaa tttctcatga taaaatcaaa gaaaaagcag attatattac aaaaacatta
    32041 gaagaagatg gcatttttga tgccttagaa gtatttggta tggtagaaaa agaattgcat
    32101 tttccacaag tagacattga aacagtagaa ggtcctcttg cgactattaa gaccaatcac
    32161 ggagacttac gtatcaagct tttccctgaa catgctccta aaacagtggc taactttgta
    32221 tctctttcaa aagatggcta ctatgatggt gtcattttcc accgtattat caaggacttt
    32281 atgatccaag gtggagaccc aactggaact ggtatgggtg gcgagtcaat ctacggcgaa
    32341 tcttttgagg atgaattctc agaagagctt tacaatatcc gtggtgctct ttccatggca
    32401 aatgctggtc caaataccaa cggcagccag ttctttatcg tgcaaaacca acacctacct
    32461 tattctaaga aagaaattac tcgtggtggt tggccagaac cgattgcaga aatctatgcc
    32521 aatcaaggtg ggacacctca cctagaccgc cgtcacacgg tttttggtca gttagctgat
    32581 gaagcatctt acgctgtctt ggatgccatt gctgctgttg agacaggagc tatggacaag
    32641 ccagttgaag atgttgtaat tgaaactatt gaaatcgagg actaagatga aaatcggtga
    32701 taagctaaag gggcgtatta cagggattca gccctacggt gcctttgttg agttagagac
    32761 gggtgatacg gggctgattc acatttcaga aattcggaca ggatttattg aaaatattca
    32821 tgaaaccttg aaagtcgatg aagaggttca agttcaggta gtggatttag atgaatttac
    32881 ggggaaagcc agtctttcta tccgcacttt ggaggaagaa aagtaccagt ttcctagacg
    32941 gagacgcttt tcaagcgacc gctttaacta cggttttgct ccctttcgac gaatgctacc
    33001 aatctggact ggagaagccc tgcactattt aaaaaagaag aagtagttta gagttttata
    33061 ttttttgtaa tgttaatata aatttgctat aataggacca tggaagaaga acaattatta
    33121 aaatcaggag agcgcattaa ccagctcttt tcgacagata tcaaaatcat tcaaaataga
    33181 gaggttttta gctattcggt ggatagtgtt ctcttatcac gatttccacg ttttcctaag
    33241 aaggggttga ttgtagattt ctgtgctggg aatggagcag tggggctttt tgctagcact
    33301 cgtactcaag cacagatatt gtctgttgag attcaggagc gtttggcgga tatggctgaa
    33361 cgctctgtcc gtttgaatgg attagaggag caaatgcagg tcatctgcga tgatttgaaa
    33421 aatatgcctg ctcacattca ggggagtaag gtggatatga ttttgtgtaa tccaccctat
    33481 ttcaaggtgg atcctcattc taatctgaac gagagtgaac attatctctt ggctcgacac
    33541 gaaatcacga ctaatttgga agaaatctgt catagtgccc agagtattct caagtctaat
    33601 gggcgtttgg ccatggttca tcgtcctgat cgacttctgg atattttgga tacgttaaaa
    33661 cgacataatc tagcccctaa gcgcctgcag tttgtttatc caaaaagaga aaaggaagcc
    33721 aatatgcttt tgattgaggc gatcaaggat ggctcaacaa gtggctttaa ggtcttacct
    33781 cctttgattg tccacaatga tgatggctct tatacgcccg aaatcgaaga gatttattat
    33841 ggatcataag gcttatatgt acgttctgga gtgtcgtgat ggatcctact atataggcta
    33901 tacgactgat gtgagaagac gcctcgctat ccacaatagt gggaagggag ccaaatatac
    33961 acgagcacgc ttgccagtca aacttatcta tgctcaaggt tttgccagta aggaagaagc
    34021 catgtcggct gaagctcttc tcaagcgtaa gaagaggcca cagaaggaag aatttttatc
    34081 tgaaaatcaa gatagaaatt tactcagtta ttttgaagaa tcgtggggag tcctttgact
    34141 cctcttacct ttgtcaaaaa gcgaaaaaaa tgctacaata aagaaaataa acaaaatgag
    34201 gtattatcat gtccaagatt ctagtatttg gtcaccaaaa tccagactca gatgccatcg
    34261 gatcatctgt agcttttgcc taccttgcaa aagaagctta cggtttggat acggaagctg
    34321 ttgcccttgg aactccaaat gaagaaacag cctttgtctt gaactatttt ggtgtggaag
    34381 caccacgtgt tatcacttct gccaaagcag agggggcaga gcaagttatc ttgactgacc
    34441 acaatgaatt ccaacaatct gtatcagata tcgctgaagt agaagtttac ggtgttgtag
    34501 accaccaccg tgtggctaac tttgaaactg caagcccact ttacatgcgt ttggagccag
    34561 ttggatcagc gtcttcaatc gtttaccgta tgttcaaaga acatggtgta gctgtgccta
    34621 aagagattgc aggtttgatg ctttcaggtt tgatttcaga tacccttctt ttgaaatcac
    34681 caacaacaca cccaacagat aaaatcattg ctcctgaatt ggctgaattg gctggtgtga
    34741 acttggaaga atatggtttg gcaatgttga aagctggtac caacttggct agcaaatctg
    34801 ctgaagaatt gattgacatc gatgctaaga cttttgaact caacggaaat aatgtccgtg
    34861 ttgcccaagt gaacacagtt gacatcgctg aagttttgga acgccaagca gaaattgaag
    34921 ctgcaatgca agctgccaac gaatcaaacg gctactctga ctttgtcttg atgattacag
    34981 atatcgtcaa ctcaaactca gaaatcttgg ctcttggtgc caatatggac aaggtcgaag
    35041 cggctttcaa cttcaaactt gaaaacaatc atgccttcct tgctggtgcc gtttcacgta
    35101 agaaacaagt ggtacctcaa ttaactgaaa gctttaatgc gtaagatttt gggtgtcagc
    35161 tcaaaatcgg aaagtctagt ttgccttata tcgaaaggag tttcggctcc tttttttcta
    35221 ggagtgaagt atgttagaaa atggcgattt gatttttgtg agagatgggt cagacatggg
    35281 acaggccatc cagacttcca caggtaacta tagccatgtt gccatttatt tggatgggat
    35341 gatttatcat gctagtggac aggctggtgt tgtctgtcaa gaaccggcag acttctttga
    35401 gtccaatcat ttatacgacc tctatgttta cccagaaatg gatatccagt cggtgaagga
    35461 aagagcttgc agacatcttg gagcacccta caatgcttct ttctatccag atgcagctgc
    35521 tttctactgc tcccagtata tagcagaaat cctacctatt tttgaaacta ttcctatgaa
    35581 atttggagat ggggaacagg agattagtga tttttggagg gagtattaca tagaactagg
    35641 tctgcctgtt cctctgaacc aagctgggac caatcctagt cagttggcag catcgcctct
    35701 gttacaatgt aaagaaaggg atcttcatga ttcagatttt taatccatct cgtttgacga
    35761 gacagccatt tttggagaat tgatccgcta tctggaccag tatgaggatg tgattctacg
    35821 ggaaattaag tctcagtttc cagatgttgc agttgataaa ctcatggaag agtatataaa
    35881 ggcaagcttg attctacgtg aaaataagcg ctattacctt aattttccta cgcttgaatc
    35941 acttgatagt cttgaactgg atcaagagat ttttgtcaga gaagctagtc cggtctatca
    36001 agccttgttg gagcagagtt ttgagacgga attgcgcaat caaatcaatg cagctatttt
    36061 agttgaaaag acggactttg cgcgcattaa aatgaccctg tccaattatt tttacaaggt
    36121 caaacagcag tatcctttga cagaaaaaca gcaggagctc tatgacattt taggagatgt
    36181 taatcctgag tatgccctca agtatatgac ggcttttttg ttgaaatttc tcaaaaaaga
    36241 ccagcttatg cagaaatgcc gtgatatctt tgtggacagt ttggttgtct taggctatat
    36301 tgtgcaaaat gaagatagaa agtatgagtt ggctatcgat tttgataagg agagattaac
    36361 tttctactta gcgtgatttc ttgtttctga gcacattgtt tgactttcct tagtattcgg
    36421 tataaactat atgtaaccgg taacacatat cggaataaac taaaggagac aatcatatgt
    36481 cacttgaaaa caaattggaa caagcaacag gcgctgtcaa agaaggtttt ggtaaagtta
    36541 ctggagacag caagacagaa cttgaaggag ctgttgaaaa aacagttgct aaggcaaaag
    36601 acgttgtaga agacgcaaaa ggtgctgtag aaggtgccgt tgaaggtttg aaaaacgttt
    36661 ttactaaata ataggaaaaa atcaagggtt tcattttccc ttgatttttt ctattcttat
    36721 aaataatttt ctgcgacggc tgtatctcct gggtaggatt ctttcttgcc ctggatgatt
    36781 tggtaacaat cggctccctt acccgcaata ataactgcat ctaattcgtg atttgtgata
    36841 gccattgccg ccttgatggc ttcttggcga tccgcaatct tttcaacagg atgattgatg
    36901 tagctactaa tttcatctgc aatggccatt gggtcttcat agttagggtc atcagcagtc
    36961 agaaagactt gaatctcagg gtgttgattg aggaggaggc caaagtcctt acgacgactt
    37021 tctcccttgt ttcctgttga tcccagaacc agagcaatct ttccggtttg atgagtttca
    37081 accacattga tgagtttttt cagactatcc ccattgtggg catagtcgat gaagaccttg
    37141 gctccatttt tctgagtgag gacttccata cgaccaggaa cgcgggttgc agcgatgcct
    37201 tttttgatgt cctcaagact tgctccgaga cggagacaag caagtccagc agcaactgca
    37261 ttttcttggt tgaagttgcc aatgagttgg atatcataat ctccagcgag tttacccgta
    37321 gctgaaaagc taaaggcttt ggaattctcg atttggttat caaattggct accatagaaa
    37381 tcatggtctt gatcttcaac ctgttctttc aagactgaga agtggtccat gtcactgtta
    37441 atgatgactg ctcggctatt ttccatcaag agacgcttgt ggtagaaata gtcttcaaag
    37501 ctagggtgtt caatcgggcc gatatggtca ggagtgatgt taagaaagac tcctacatca
    37561 aaggtcagtc catagactcg atggactaga taggcttggc tagagacttc cattacgaga
    37621 tggcttcttc cattcttaac agcttgagcc atcatgtcaa agaggtcgat attttcaggt
    37681 gttgagaatg aagatttaaa gaaagttgtg ccatccaaag ttgtattcat ggttgataag
    37741 agggcggttg ggtaacgttg agataggatg ttgtaagcaa agtaagctgc tgttgtctta
    37801 cccttagttc ctgtgaaggc gagaattttg agtttctctt gtggattacc atagaactcc
    37861 atggcaatca aactcatggc tttctttata tcgttcacaa tgatgacagg gataccgact
    37921 tcgtagtcct tttcagctac ataccaagct aaaccttgtg ttatagcaga aagaaggtat
    37981 tcttttttaa aggcagcacc ttttgcaaaa aaaagagtgt cttctgttac ttttcggctg
    38041 tcgtagctga tgctatcaaa aacaactttg ctgtagttgt agtggtaatg accttggtca
    38101 ataatttcgc gaaaaaggcc atctttcttt aaaatatcta atacagtttc aatttttatc
    38161 atactttcta ttgtaaaccg aaagtcgcaa atttacaagt aacaaggaaa agtttataat
    38221 ggaagataag gagtttttcc tagttatcaa aattgaatga ggaatctatg tcgcacgaaa
    38281 acaatcacca gcaggcccag atgttacggg ggactgcttg gctaacggct agtaacttta
    38341 tcagtcgcct actcggggct gtttacatta tcccttggta catctggatg ggggcttatg
    38401 cagctaaggc aaatggtctc tttaccatgg gttacaatat ctatgcttgg ttcttgttgg
    38461 tttcaacagc ggggattcca gttgcggtgg ccaagcaagt tgccaagtat aataccatgc
    38521 gagaagaaga gcatagcttt gccctgattc ggagcttctt aggctttatg acaggactag
    38581 gcctggtttt tgctttagtc ttgtatgtct ttgctccttg gctagcagac ttgtctggcg
    38641 tgggcaaaga cttgatccca atcatgcaaa gcttggcttg gggagtcttg attttcccgt
    38701 ctatgagtgt tatccgagga tttttccaag ggatgaataa cctcaaacct tatgccatga
    38761 gccaaattgc tgagcaggtc attcgtgtta tctggatgct cctagcaacc tttatcatta
    38821 tgaagctcgg ttcaggagat tatctagcag ccgttaccca atcaaccttt gctgcctttg
    38881 tcggtatggt agccagtttt gcagtcttga tttatttcct tgcccaagaa ggttcactca
    38941 aaagagtctt tgaaacagga gataagatta acagtaagcg tctcttggtt gataccatta
    39001 aggaagccat tccttttatc ctgacagggt ctgccatcca gctcttccag attttggatc
    39061 agctgacctt tatcaatagt atgagctggt ttaccaacta cagcaatgag gacttggttg
    39121 tcatgttttc ttatttctca gccaatccta ataaaatcac gatgattttg atttctgtag
    39181 gggtttcgat tgggagtgtt ggtttgccac ttttgacgga aaactatgtc aagggggact
    39241 tgaaagcggc ttctcgtctc gttcaggaca gtctcaccct actctttatg ttcttgctac
    39301 cagcaacggt tggagtggtt atggtaggag aacctcttta tacggtcttc tatggtaagc
    39361 cagatagttt ggctctgggc ttatttgtct ttgcagtttt gcagtctatt attttaggct
    39421 tgtacatggt cttgtctcca atgcttcagg ccatgttccg caaccgcaag gccgttctct
    39481 attttatcta tggttctatt gccaagctag tcttgcaact acctaccatc gccctcttcc
    39541 acagttatgg tcctttgatt tcaacaacca ttgctctcat cattcctaac gtcttgatgt
    39601 atcgggatat ttgtaaagta actggtgtca agcgcaaggt gattttgaag cgaaccattt
    39661 taatcagttt gctgacccta gtcatgtttc tgttaatagg aaccatccag tggctgttag
    39721 gatttttctt ccaaccaagt ggacgtttgt ggagcttctt ttatgtagct cttgtcggtg
    39781 ccatgggggg tggactttat atggttatga gtctgcgtac ctatttatta gataaggtaa
    39841 taggaaaagc ccaagcagat cgcctgcgag caaaatttaa gctttcgtaa ggtagcattt
    39901 ataaataaaa ggaataagtt gaacaatctt ttaggagaac ttgaaactta ttcctttttt
    39961 agcgtcaaaa tagctaaaat tatctttcaa aaatagaaaa tgagtttttt gattttttgg
    40021 aaaaaacaat tgactaaaca aaccaagagt tgtataataa aacaaatatt taaagcagga
    40081 ggttctggaa atgaaaaagt ctaagagcaa atatctaacc ttggcaggtt ttgtcctggg
    40141 tacaggagtt ttattgagcg cgtgtggaaa ttctagcact gtatcaaaaa cctataacta
    40201 tgtttattca agtgatccat ctagtttgaa ctatctagca gaaaaccgcg caacaaccaa
    40261 tgatattgtg accaatctgg tagatggtct catggaaaat gaccaatatg ggaactatgt
    40321 gccatccttg gcagaagatt ggactgtttc tcaggatggt ttgacctata cctacaaact
    40381 tcgtaaggat gccaagtggt ttacttctga gggagaagaa tatgcacctg taactgccca
    40441 ggattttgtg acaggattgc aatatgcagc tgataaaaaa tcagaagcct tgtatctagt
    40501 gcaggactct gttgcaggtt tggatgacta tatcactggt aaaacaagcg acttttcaac
    40561 tgtcggtatc aaggctcttg atgatcaaac cgttcaatac accttggctc gaccagaacc
    40621 ttactggaac tcaaaaacaa cctcaaccat tcttttccca gtcaatgcag atttcttgaa
    40681 atcaaaaggg gatgattttg gcaaggtaga ccctgctaat attttgtaca gtggaccttt
    40741 cttgatgaaa gcttttgttt caaaatctgt catcgaatac aagaaaaatc ctaactactg
    40801 ggatgctaaa aatgtctttg tagacgatgt gaaattgacc tactatgatg gtagtgacca
    40861 agatgctctt gttcgtaact ttacagacgg agcctatagc tatgcccgtc tctatccgaa
    40921 tagttcaagt tttgaaggga ttaaagaaaa atacaaagat gatatcatct acagtatgca
    40981 ggatgctacg tcttattact ggaattttaa cctagataga caagcttata aatttacttc
    41041 taagacgacc gacattgaaa agaaatcaac tcaggaagca gttcttaata aaaacttccg
    41101 tcaagctatt aactttgcct atgatcgtac ctcctatggg gctcaaactc agggagaaga
    41161 cggagcgact aagattttgc gtaacttggt tgttcctcca acctttgtaa gtatcaaagg
    41221 aaaagatttt ggtgaagtag tagcctctaa gatggtcaat aattatggta aggaatggca
    41281 aggcatcaac tttgcggatg gtcaagaccc ttactacaat cctgagaaag ccaaggctaa
    41341 atttgctgag gccaagaaag agctagaagc taagggagtt caattcccta ttcatttgga
    41401 tgcgacagtt gaccaagctt ctaagaaggg gattcaagaa gtaagctcca tgaagcaatc
    41461 tattgaagca gctttaggta cggagaacgt cgttattgat atccaacagt tatcaacaga
    41521 ggactatgat aactcaagtt accttgctca gactgctatt cagaaagact acgaccttta
    41581 caatggtggt tggagtcctg actacttaga tccatcaacc tatcttgata tctttagtgt
    41641 caagaatggt ggggttctac aaaatcttgg actcgaccct ggtgaagcca atgacaaggc
    41701 taaggcagtt ggacttgaca cttatactca aatgttggaa gaggctaata aggagcaaga
    41761 cccagccaaa cgttatgaga aatatgctga tattcaagca tggttgatag atagttctct
    41821 agcgattcca aatgtttcat taggtggaac gcctagcttg agaaaaacag ttcctttctc
    41881 agcaccttat tcattggctg gtaataaagg ggttgaatca tataaatacc tcaaagtaca
    41941 agataagatt gtcacaacag acgaatatgc aaaagccaga gaaaaatggt tgaaagaaaa
    42001 agaagaatcc aataaaaaag cccaagaaga attggcaaaa catgtcaaat aaaatctaat
    42061 tgtagataag tttgtgtaag aagtctttgt gcttaaaaac gcataatatc aggtatataa
    42121 aatcctagat gttatgcgtt ttgttatagg aagatttatt agattttatc ctcaaattga
    42181 gttattcccg actttatccg ttgaaatatt ataaggagta tttatgaaat taaaattatt
    42241 aagagtagat actaaggtga ttatgtggag tttcttactt gttctgtcta gtctacttgc
    42301 tttgttgctt ccccttatct taaagggttt aatagatggg agttctattg aaaatatagg
    42361 ttccaaagta tttcaatcgt ttttgatttt tattggtcaa gccttgtttt cttctattgg
    42421 ttactatctg tttagtcaat cgggtgaaaa aagatagcaa aaatcaggaa aaaagtgata
    42481 gaggggttga tttatgcaga gaaatccttc tttgataaga gccaaagtgg ggagttgact
    42541 tctgccattg tcaatgacat gagtgtcatt cgtgagtttt taattacgac tttcccaaat
    42601 attattctga gtttagttat ggtacttggt tccattgtag tcttatttag tcttgattgg
    42661 aatctttctc tacttttatt catcactctt ccttgtatga tgtttattat cttgcccctt
    42721 tccaatatca gtgaaaagta tagtcgtcgt ttacaggagg aaatcggatt tttaacaggg
    42781 caattgactg aaaagattca agaacatgaa ttaattaaga ctaaccaagc agagaaaagt
    42841 gtacaggatg ttttggataa ttgtattgaa agggtacaaa acaattcact gaaatcagat
    42901 agggttactt cttttgagac cccgtttgct ctcttattta tctttgcgac tatagttgtg
    42961 atgctaacct atgggggtta tcgggtcagc gcaggatata tatctgtggg aaccttggtt
    43021 tcgtttttga tttacctctt tcaattactt aatcctatta gtaatatagc taattttgta
    43081 actatttatt ctagtagcaa gggatcttca gttgcactgg agaacttgct tgcagttcct
    43141 aaagaaaaat ttgagggagg aaaatcggta tcaggacaag ggttgaattt taaccatgtc
    43201 tattttggtt atgatgaaaa tcgacctgtc ttaaaggata ttacttgttc aattttcaag
    43261 gggcaaaaaa ttgcttttgt tggaccatct ggatcaggaa aatcaacgat tgtgcgtttg
    43321 ttagagcggt tttataaacc gctttcagga gatattctaa tggagcaatc aagtatatat
    43381 gattttaact taaaagaatg gagaagtaaa atcgcttggg tttcacaaaa taatgcagtc
    43441 ttatctggca gtattcgtga caatctttgt ctcggtttga atcgcttagt aactgatgat
    43501 gaattgatga aagtgctaga cttagtatca ctaggtgatg agattcgctc catgaaagag
    43561 ggactagata ctgaagttgg tgaacgcgga cgattcttgt caggggggca aagccaaaga
    43621 cttcaaatag ctagaaccta cttaaaagat gctgaaattc ttatatttga tgaagccact
    43681 gctaatcttg atgcggattc tgagtatgcg attatcagta gcctctattc tgtattaaag
    43741 gagaagacgg ttgtgattat agcgcatagt ttgtcaacgg taaaagatgt ggattgtatt
    43801 ttcttcttag aggaggggaa aatcactggc tcaggaactc ataaggaact actggaaaat
    43861 catgagcgtt atgctcgttt tgtgcaggag caaatgatag agtgaaggtg tcttttgaga
    43921 ttcaccattt tatagtctat taaagggagc aggaaaaact ccctttttat atagtttgaa
    43981 actataacta gctcttgaaa agaagaaaat gagttgatga aaataagtgg tacaatagtt
    44041 actatagatt tggaggtatt gtatgagcaa ggaattacac attaacacaa ttttggccca
    44101 ggcgggtatt aagtcagatg aggcaacagg tgctttggtg acaccacttc atttttcaac
    44161 gacctatcag catccagagt ttggtcgatc tactgggttt gactatacgc gcactaaaaa
    44221 tccaactcgt agtaaggctg aggaagtctt ggcggctatt gagtcagcag actatgccct
    44281 agcgactagc tcagggatgt cagctattgt actggccttt agcgtctttc cagtaggaag
    44341 taaggtcttg gcagtgcgtg atctttacgg tggttctttt cgctggttta accaagtgga
    44401 gcaggaaggt catttccatt ttacctatgc caatacagaa gaagagttga ttgccgagtt
    44461 agaaaaggat gtggatgttc tctatatcga aaccccaacc aatcccttga tgttggaatt
    44521 tgatatcgaa aaactagcaa aattggctca tgctaagggt gccaaagtgg tggtggacaa
    44581 taccttctat agccctatct accaacgtcc gattgaagat ggagcagata tcgttctcca
    44641 ttcagcaacc aagtatctag caggccacaa tgatgtcttg gctggagtgg ttgtgaccaa
    44701 tagtttagaa ctatacgaga agctttttta caatctcaat acaacagggg cagtcttgtc
    44761 tccatttgac agctaccagt tgcttcgtgg tctcaagacc ttatctcttc gtatggagcg
    44821 ctcaacagct aacgcccaag aagtggttgc ctttttgaag gattctccag cagttaagga
    44881 agttctctac actggtcgtg gaggcatgat ttcctttaaa gtagccgatg aaacacgcat
    44941 tcctcatatt ttgaacagtc tcaaggtctt ctcttttgcg gaaagtttgg gcggagtgga
    45001 aagtcttatt acttatccaa cgactcaaac tcatgctgat attccagcag aagtacgcca
    45061 ttcttatggt ttgacagatg acctcttgcg tttgtctatt gggattgagg atgctagaga
    45121 tttgattgca gatttgcgcc aagccttaga aggataagac aaagatggga aaatatgatt
    45181 ttacaagcct gcccaaccgt ttagggcacc atacctataa atggaaagaa acagaaacgg
    45241 atagtgaagt tctaccagct tggatagcgg atatggactt tgtggtcttg cctgaaatcc
    45301 gccaagccgt gcaaacttac gcagaccaac tggtttatgg ttatacctat gccagtgaag
    45361 acttaattaa ggaagttcaa aagtgggaag ctacacaata cggttacaac tttgacaaag
    45421 aggctcttgt ctttatcgag ggtgtggtac cagccatctc aacagctatt caaaccttta
    45481 caaaagaagg cgaggcggtt ttaattaaca cgcctgtcta cccacccttt gctcgcagtg
    45541 tcaagttgaa taatcgtaga ttgattacta attccttagt ggaaaaggat agtctgtttg
    45601 agattgactt tgaccaactt gaaaaggatt tggtggaaga ggaggttaaa ctctatgttc
    45661 tttgcaaccc tcacaatcct ggtggacgtg tttgggaaaa agaagtgttg gagaagattg
    45721 gccaactctg ccaaaaacac ggtgttttgt tagtttcgga tgagattcac caagatttga
    45781 ccctctttgg tcacaaacac cagtctttca ataccatcaa tcctgccttc aaaaattttg
    45841 ctatcgtctt gagcagtgcc actaaaacat ttaatattgc tggaacaaaa aattcctatg
    45901 cagtcattga aaatcctaag ttgagactgg ctttccagaa acgcctgttg gccaataatc
    45961 agcatgaaat ttcaggcttg ggttatttgg cgacagaagc tgcctatcga tacggtaaag
    46021 attggctaga ggaactcaag caagtctttg aagaccacat caattatgtg atggatctat
    46081 ttggaaaaga gactaaaatc aaggtcatga aaccgcaagg tacctacttg atttggcttg
    46141 acttttcagc ttatgacctg actgatgaaa cattgcaaga gttgttgaga aatgaagcca
    46201 aggttatcct caaccgtggt ttggattttg gagaggaagg aagtctccat gcccgcatca
    46261 atatagctat gcccaaatct ctgttgcaag aagtctgtca gcggattgtg gctacttttg
    46321 ccaaacgtta aaaatccagc cttctaggag aaaagtcttc ctagaaggct attttcatag
    46381 gcgaaaatat ggtataataa aaagataagg taaaggtgaa aatatggcta aattgattcc
    46441 ggggaaagtt cgtatcgaag gtgttgccct ttatgaaact ggtaaggttg atatcatcaa
    46501 ggaaaagaac aatcggctct acgctcgcgt tgcagaagaa gaactgcgct atagtttaga
    46561 ggatgatttg gttttttgtg cctgtgattt ttttcaaaag aggggttact gtgtgcattt
    46621 ggcagcgcta gagcattttc tgaaaaatga tgagcgtggt caggaaatct tgtggagtct
    46681 ggaagaaggt catgaagaaa aagaggccgt tgaaaccaag gtgaccttgg gtggcaagtt
    46741 tttggatcga attttatctc caaaatcaga atgcgcctat gagttatcag ctgtgggtca
    46801 ggtggaagca ggaaccaatc atatcttgtg gactctgaga atcggccaaa tcaatagcca
    46861 aaaatactat gtcattcggg atattccact ttttttaagg attgtcgagc agagaaagtc
    46921 gtatatgatt ggcaagattt atgaggagtc tctttcttgg gaagcctttg atgatgccag
    46981 ccaagaactt ttgactttct tgcacggact aacggaggaa gggctggttt cagacctctt
    47041 tttccaaaac caaggtcggc acctcttttt ccctctgacc ttttttgagc agggtgtgaa
    47101 tttactgatg gccttgcccc attttcaatt tgaccatcaa gtggatagct accaaaccct
    47161 gctttttcag gatatgcatg ctgatgccaa tctatttgcc tttacagtaa cagaatactc
    47221 ggactatttt gaaatggaaa tcagtgagag tcctagggtc aatgtctttt atcagggagc
    47281 agtacttttc cataaaggtc aggtttattt tttaacagac cagcagatgc gtcttctcaa
    47341 ggaaattaaa gcgttacctg tgggtcaaca aggaaagaaa tacctgcaat ttgatagcag
    47401 tgatcgagac aaattggcct cctgtctgac tctttttatc cagatgggca ccgtttcagc
    47461 tccagaacgt ctacaaatca aaacttttgc gccctctttt tactttgaca gggaagaaga
    47521 taatcggatt cgtttggaaa ttcagtttga ttatggaaat agacaggtat ctagccgaca
    47581 agagctagaa gaattaccat tttcaagtga cgcagactta gaagaaagaa ttttccaagt
    47641 ctgtttggct gcgggctttg aagccgattt tcaatcttgg cgtcaggcct taaaagcgga
    47701 gtctgtctat catttttttc atgatatcat tccagtcttt gaaaaactcg ggcatgttga
    47761 cctatcagat aaactagaag agctttatag cctagcgagt cctcaggtgc agattgcctc
    47821 caagggaggt ctcttggaaa tccagtttga ttttcaagat attgcccagg aggaaatcga
    47881 ccaagccatg caggccttgg ttgccaatca ggatttttat attgattcgt ctaatcaagt
    47941 ttactttttc gatgaagaaa ccaagaaaat tcgccaaaat ctacaggaac tggggcaatt
    48001 tgaattaaaa gatgggacct tgcaggctcg gaaatccttg gcctacagtt tagctcatct
    48061 ctttgaaggg cgagaccgtg tttctttttc acaagaattc cagaatctgg cccaggattt
    48121 gacacatcca gaggactttc ctcgacaggc aactcaggtt caggctgact tgcgagatta
    48181 tcaggaaaag ggaattggct ggttgcagat gctccatcat tatggttttg gtgggatttt
    48241 ggctgatgat atgggacttg ggaaaaccct tcagaccatt gcttttttga ctagtcaagt
    48301 gacaaaagaa agtcgggttt tgattctcgc tccgtcaggt ttgatttaca actgggcaga
    48361 tgagtttcag aaatttgccc cacagttgga tgtggctgtt gttcatggtt tgaaagcaag
    48421 tcgtgaggag attcttgccg agagccatca aatctatgtg actagctatg ccaccttccg
    48481 tcaggacagt gagttttatc aggggatggc ctttgacttc cttttcttag atgaggctca
    48541 ggtcatgaaa aatgcccaga ccaagattgc ccagaccttg agacaatttg tggtgccgtc
    48601 ggtctttgcc ttgtcaggaa ctccgattga aaaccatctg ggtgagttgt ggtctatttt
    48661 ccaaatcgtc atgcccggac ttttgccaag caagaaagaa tttatgaaat tgccagcaga
    48721 gcgagtggct cagtttatca agcctttcgt gatgcgacgc aagaaagaag aagttctgac
    48781 tgaattgcca gacttgattg aggtggttta taaaaatgaa ctggaagacc agcaaaaggc
    48841 tatttacctt gcccagttac aacagatgcg agaccatctg gctcaagtgt cagaacagga
    48901 atttcagcga agtcgtgtgg aaattttatc tggtttgatg cgcttgcgtc aaatatgtga
    48961 cactcctgcc ctgtttatgg aagattatca gggagccagc ggcaaactag atagtctccg
    49021 agacctactg gtacaggtgg cagacggcgg acaccgtgtc ttgattttct ctcagttcaa
    49081 gggaatgttg gaaaaaattg aacaagaact gccagacttg ggcctgacat cctttaaaat
    49141 tacgggttca accccagcca aggaaagaca agacatgacc aaggccttta accaaggaga
    49201 aagagatgcc tttctgattt ccctcaaggc tggtggggtc ggtctgaacc tgacaggtgc
    49261 agatacagtg atcttggttg acctttggtg gaatcctgcg gtggaagcgc aagccattgg
    49321 ccgtgcccat cggatgggtc aggaagaaac ggttgaggtc tatcgcttgg tgaccaaggg
    49381 aaccattgaa gaaaaaattc aggaactcca agaacaaaag aaacatctgg tgtcacaagt
    49441 attggatggc acagagtcac gtggtagtct gaccctagca gaaattagag aaattttggg
    49501 aatttctgaa gccagcactt gaaaaatcaa gacaatacgc tataatgaag tgttgaaagg
    49561 aaatagaaaa tgaaacaaga acgatttcca ttggtgtcag atgacgaggt catgttgact
    49621 gaaatgccag tcatgaatct ctatgatgag tctgatctga tcagtaatat caagggtgag
    49681 tatcgagata aaaattattt agaatgggct cctattactg aagaaaaacc agtaaaaccg
    49741 attgaaaagc aagtcgaaaa acctaaaaag gctcctttag gggttaaaaa agaaggaaag
    49801 agctatgcgg aggtggcgcg tgaagaagcg cgtgcggact tgaaaaagaa acgctctgct
    49861 aactacctaa ctcaggattt cagccttgcg agacgtcatt ctcagcccag tctagttaga
    49921 cagggcaatc aaccgacaac tcctttccaa aaggaaaatc ctggtgaatt tgtcaaatat
    49981 agccaaaaat tgacccagtc tcattatatc ttggcggaag aagttcattc tatccctacc
    50041 aagaatgaag aagtgtcagc acctgctcca aagaaaaaca attatgattt tctaaagaag
    50101 agccaaatct acaataaaaa aagtaaacaa acagaacaag aacgtcgggt tgcccaagag
    50161 ttgaatctga ccagaatgac agaatagggg agaaaacatg tcaaagacat atcattttat
    50221 cggaattaag ggatcaggga tgagtgcctt ggccttgatg ttgcaccaga tggggcacaa
    50281 ggttcaggga tcagatgttg aaaagtacta ctttacccaa cgcggtcttg agcaggcagg
    50341 aattaccatt cttccttttg atgaaaagaa tctagacggt gatatggaaa ttatcgctgg
    50401 aaatgccttt cgtccagata acaacgtcga aattgcctat gcggaccaaa atggtatcag
    50461 ctacaaacgt taccatgagt ttctaggtag ctttatgcgt gactttgtta gcatgggagt
    50521 agcaggagca catggaaaaa cttcaacgac aggtatgttg tctcatgtct tgtctcacat
    50581 tacagatacc agcttcttga ttggagatgg gacaggtcgt ggttcggcta atgccaaata
    50641 ttttgtcttt gaatctgacg aatatgagcg tcacttcatg ccttaccacc cagaatactc
    50701 tattatcacc aacattgact ttgaccatcc agattatttc acaagtctcg aggatgtttt
    50761 caatgccttt aacgactatg ccaaacaaat taccaagggt ctttttgtct atggtgaaga
    50821 tgctgaattg cgtaagatta cgtctgatgc accaatttat tattatggtt ttgaagctga
    50881 aggcaatgac tttgtagcta gtgatcttct tcgttcaaca actggttcaa ccttcaccgt
    50941 tcatttccgt ggacaaaact tggggcaatt ccacattcca acctttggtc gtcacaatat
    51001 catgaatgcg acagccgtta ttggtcttct ttacacagca ggatttgatt tgaacttggt
    51061 gcgtgagcac ttgaaaacat ttgccggtgt taaacgtcgt ttcactgaga aaattgtcaa
    51121 tgatacagtg attattgatg actttgccca tcatccaaca gaaattattg cgaccttgga
    51181 tgcggctcgt cagaaatacc caagcaagga aattgtagca gtctttcaac cgcatacctt
    51241 tacaagaacc attgccctgt tggacgactt tgcccatgct ttaaaccaag cagatgctgt
    51301 ttatctagcg caaatttatg gctcggctcg tgaagtagat catggtgacg ttaaggtaga
    51361 agacctagcc aataaaatca acaaaaaaca ccaagtgatt actgttgaaa atgtttctcc
    51421 actcctagac catgacaatg ctgtttacgt ctttatggga gcaggagaca tccaaaccta
    51481 tgaatactca tttgagcgtc tcttgtctaa cttgacaagc aatgttcaat aggatgttcc
    51541 catggaaatt ccaattaaga tcattcaggc aagcaagttt gatttgcctg agataggggc
    51601 acttcagacc tcgtcttttc cagctgaaaa gcagcaactt tcccatattt tagaagaaag
    51661 tatccgtaag tgtgcggata cctttcttct agctagggat gaaaatcaac ttttaggcta
    51721 tattttatca agtccccagt cagacaatcc gcaatgtcta aaagtacatt ctttagtcat
    51781 cgagtctgac catcagagac agggcctggg aacacttctt cttgcagcct tgaaagaggt
    51841 ggcagttgag ctggattaca aagggattcg tttggagagt cctgatgagc tgctttccta
    51901 ttttgaaatg aacggttttg ttgatgaaga agaaactttg ctctatgcaa ctagccaggg
    51961 ctatagtatg atttggttta atccctttta tctggaggaa caatgaaaat cagacaagca
    52021 agattagaag atttggatcg gattgttgaa cttgaatttg aaaatttttc ggtcgaagaa
    52081 gccattcctc cttctgtctt tgaagcacat ttgagagaaa ttcagacctc ttttctggtt
    52141 gctgaaaaag aaggaagaat catgggttat atcgaaggac cagttggcct gcaccgccat
    52201 ctgcaagacc agtcttttac agaagaaata aaagactata gtcatgagcc tggtggttat
    52261 atctctgtga cctgtctgtc tattgccaag gaggcacagg gactcggact gggtcagaaa
    52321 ttgctgacag ccttgaaaga agttgctctt gaagatgaga gagatggcat taatctaacc
    52381 tgtcatgact atctcatcgc ctattatgaa aaacatggat ttgtcaacga aggccagtcc
    52441 cagtcaacct ttgcagggga aacatggtat gatatggtct gggaaatgaa aaaataagtt
    52501 aggaaaagta tcatagattg ctttttttgg acttttaaga tataatatta tggattatca
    52561 acaaggagga aaaacttttg agtgaaaagt caagagaaga agagaaatta agctttaaag
    52621 agcagattct gagagattta gaaaaagtaa aaggctatga tgaagttctg aaagaagatg
    52681 aggcagtagt tcgcactcct gcaaatgaac cttcagctga agaactcatg gctgattcct
    52741 tgtcaacggt agaggagatt atgagaaaag ctcctaccgt gcctactcac ccaagtcaag
    52801 gtgtaccagc ttctccagca gatgagagtc aaagagaaac tcctggtgtt ccaagtcatc
    52861 caagtcaaga tgtaccttct tctccagcgg aagaaagtgg atcaagacca ggtccaggtc
    52921 ctgttagacc taagaaactt gaaagagaat acaatgaaac cccaacaagg gtagctgttt
    52981 cctatacgac ggcagagaaa aaagcagaac aagcaggtcc agaaacacct acgcctgcta
    53041 cagaaatagt ggatatcatc agtgatacat cacgtcgtag ccgtagagaa ggagcaaaac
    53101 ccgttaagcc taagaaagag aagaagtcac atgtgaaagc ttttgtgatt tcattccttg
    53161 tattccttgc cttgctctca gcaggtggtt acttcggtta ccagtacgtg ctagattctt
    53221 tgttacctat cgatgctaat tctaagaaat atgtgacggt tggaattcca gaaggttcaa
    53281 acgttcaaga aatcggtacg acgcttgaaa aagctggttt ggtaaagcat ggtctgattt
    53341 ttagttttta tgccaagtat aaaaattata ccgacttgaa agcaggttac tacaatttgc
    53401 aaaagagtat gagtacagaa gacttactca aagagttgca aaaaggtgga acagatgaac
    53461 cgcaagaacc tgtacttgcg actttgacaa ttccagaagg ttataccttg gatcagattg
    53521 ctcaagctgt gggtcaattg caaggtgact tcaaagagtc tttgacagcg gaggctttct
    53581 tggctaaagt tcaagatgag acgtttatca gtcaagcagt agcgaaatat cctactttac
    53641 tggaaagttt gcctgtaaaa gacagcggtg cgcgttatcg tttggaagga taccttttcc
    53701 cagctacata ctctatcaag gaaagcacaa ctattgagag cttgattgat gagatgttag
    53761 ctgctatgga taagaaccta tctccttact atagtactat caaatctaaa aatttgactg
    53821 tcaatgagtt gttgaccatt gcttccttgg tcgaaaaaga aggtgccaag acagaagatc
    53881 gtaagctcat tgcaggtgta ttctacaatc gtttaaatcg tgatatgcca cttcaaagta
    53941 atattgcaat cttgtatgcc caaggaaaac tggggcaaaa tatcagtcta gctgaggatg
    54001 ttgcgattga taccaacatt gattcacctt ataatgttta taaaaatgta ggtctcatgc
    54061 ctggtccagt cgatagtcca agtctggatg cgattgagtc aagcatcaat caaactaaga
    54121 gcgataacct ctactttgta gcagatgtca cagaaggcaa ggtctactat gctaacaatc
    54181 aagaagacca cgaccgcaat gtcgctgaac atgtcaacag caaattaaac taaacaaact
    54241 aaaattatgt gatacgtcac ataattttct ttagaaaata ttatcagaag aaagttgaga
    54301 aaaatggcag aaaaaacata tcctatgacc cttgaggaaa aggaaaaact tgaaaaagaa
    54361 ttagaagaat tgaaattggt tcgtcgacca gaagtggtag aacgcattaa gattgcccgt
    54421 tcatacggtg acctttcaga aaacagtgag tacgaagcag ctaaggatga acaagccttt
    54481 gtcgaaggac aaatctctag cttagaaaca aaaatccgct atgctgaaat cgtcaatagc
    54541 gacgcagttg cccaggacga agtagcgatt ggtaaaacag tcaccatcca agaaattggt
    54601 gaggacgaag aagaagttta tattatcgta ggttcagctg gtgcggatgc ctttgcaggt
    54661 aaggtttcaa atgaaagccc aattgggcag gccttgattg gcaagaaaac aggtgacaca
    54721 gcaaccattg aaacgcctgt tggtagctat gatgtaaaaa tcttgaaggt tgaaaaaaca
    54781 gcctaaaaac agaaaaagga gtggggaggc gatgtgcttc actcactcct ttttccattt
    54841 tgctattctt cgaaaatctc ttcaaaccac gtcagcgtcg ccttgccgta tgtatggtta
    54901 ctgactt
//
LOCUS       DAVAGB010000008        52099 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVAGB010000008 DAVAGB010000000
VERSION     DAVAGB010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52099
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.008"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            262..1707
                     /gene="cps4A"
                     /locus_tag="VQO19_000542"
     CDS             262..1707
                     /gene="cps4A"
                     /locus_tag="VQO19_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HET1348846.1"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            1709..2440
                     /locus_tag="VQO19_000543"
     CDS             1709..2440
                     /locus_tag="VQO19_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HET1348847.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLTESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNGKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            2449..3141
                     /gene="cpsC"
                     /locus_tag="VQO19_000544"
     CDS             2449..3141
                     /gene="cpsC"
                     /locus_tag="VQO19_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HET1348848.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFTYSTFVI
                     KPEFTSTTRIYVVNRNQGEKSGLTNQDLQAGTYLVKDYREIILSQDVLEEVVSDLKLD
                     LTPKGLANKIKVTVPVDTRIVSVSVNDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNILIGFLAGVIGTSVIVLLLELLDTRVKRPEDIEDTLQMT
                     LLGVVPNLNKLK"
     gene            3151..3834
                     /gene="cps4D"
                     /locus_tag="VQO19_000545"
     CDS             3151..3834
                     /gene="cps4D"
                     /locus_tag="VQO19_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4D"
                     /protein_id="HET1348849.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVS
                     PGEGKTTTSVNIAWSFARAGYKTLLIDGDTRNSVISGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTAPIGIVI
                     DAAIITQKCDASILVTATGEANKRDVQKAKQQLKQTGKLFLGVVLNKLDISVDKYGVY
                     GFYGNYGKK"
     gene            3850..5217
                     /locus_tag="VQO19_000546"
     CDS             3850..5217
                     /locus_tag="VQO19_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET1348850.1"
                     /translation="MDEKGLKIFMAVLQSIIVILLVYFLSFVRETELERSSMVILYLL
                     HFFVFYVSSYGNNFFKRGYLVEFNSTIRYIFFFAIAISVLNFFIAERFSISRRGMVYF
                     LTLEGISLYLLNFLVKKYWKHVFFNLKNSKKILLLTVTKNMEKVLDKLLESDELSWKL
                     VAVSVLNKSDFQHDKIPVIEKEKIIEFATHEVVDEVFVNLPGESYDIGEIISRFETMG
                     IDVTVNLKAFDKNLGRNKQIHEMVGLNVVTFSTNFYKTSHVISKRILDICGATIGLIL
                     FAIASLVLVPLIRKDGGPAIFAQTRIGKNGRHFTFYKFRSMRIDAEAIKEQLMDQNTM
                     QGGMFKIDNDPRVTKIGRFIRKTSLDELPQFWNVFIGDMSLVGTRPPTVDEYDQYTPE
                     QKRRLSFKPGITGLWQVSGRSKITDFDDVVKLDVSYIDNWTIWKDIEILLKTVKVVFM
                     RDGAK"
     gene            5248..6426
                     /locus_tag="VQO19_000547"
     CDS             5248..6426
                     /locus_tag="VQO19_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HET1348851.1"
                     /translation="MKKSVYIIGSKGIPAKYGGFETFVEKLTAFQQDKAIQYYVACMR
                     ENSAKSGTTEDVFEHNGAICYNVDVPNIGPARAIVYDIAAINRAIEIAKENKDEDPIF
                     YILACRIGPFIHGIKKKIQAIGGTLLVNPDGHEWLRAKWSTPVRRYWKISEGLMVKHA
                     DLLVCDSKNIEQYIQEDYKQFQPKTTYIAYGTDTTRSILKSSDEKVRSWFKEKNVSEN
                     EYYLVVGRFVPENNYESMILGFLASNSKKDFVLITNVEQNKFYNQLLAKTGFDKDPRV
                     KFVGTVYNQELLKYIRENAFAYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVAE
                     DGADYWEKDNLHKVIEASEQKTQEEINEKNILSTKQVTERFSWDLIVNEYEKLFTRKN
                     "
     gene            6651..8042
                     /locus_tag="VQO19_000548"
     CDS             6651..8042
                     /locus_tag="VQO19_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001222819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="HET1348852.1"
                     /translation="MRISFSKKTMLCGLLYIGLILSVVTIPTIVTFLYSLLFIGIVTV
                     LNYNSILASDEDANSFFVALPIILSSFQNVYLGFGADRLNSVTLQVLLSISIAIITIT
                     VFLGIILNRFKSKEFSWLVLSILVIIIQSVILLIFFPTTLPAYLSSMRNILAPLLIFY
                     FSIYGFKNINLQKFYKYMFIIILVVLIFGFIEYIYGNSLWTRLNIKKLWALKGLAIEN
                     RVVPGNWHSSELIGGKQLRRMVSTFADPVNLGSYLFAAFMLAWYKNKKLLQVLLLASF
                     VLSVSKAAFLSMLVYIIIYTWVVDKNKILSIFGIIISTVLGLYFYNFSQVSSYGSINA
                     HIDGFFSALSTPLHYPFGMGVGSVGVLASKLGSQTALSSEVLETGIGMIIAQLGFVGV
                     IIYLIFFVKLSVIGKNINNKRDKILWFTLIYSFLANAFFNEVALSPNSCTLYFLILGL
                     LYNKNKIRSTEFS"
     gene            8042..9013
                     /locus_tag="VQO19_000549"
     CDS             8042..9013
                     /locus_tag="VQO19_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET1348853.1"
                     /translation="MEKLVSIILPVYNVEQYIKNCLESIQQQTYPNLEVIIVNDGSTD
                     KSVEYCEQICKIDSRFSITHKENGGLSDARNVGIDKAKGDYLIFVDSDDFVSQDMVSY
                     LVSCMENNEADIAICDPVHYYSDRQNNDLNIFSPASSVKVYETTEALCEMFYQKSFLV
                     SAWAKIFKRELFDDIRFPVGKLFEDSAIMYLLLEKCETIAYSDAKLYAYVHRDNSITT
                     KKFSDRDLDILEITNTIINHYGDNLRVYTAAVSYKVSACFRILLNSPSEEKYKKVQKE
                     CLSYILQNWRNILFNNNVRLKNKLALISITIFNPFVKFIYSKVNRWE"
     gene            9020..10252
                     /locus_tag="VQO19_000550"
     CDS             9020..10252
                     /locus_tag="VQO19_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001045980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 61 protein"
                     /protein_id="HET1348854.1"
                     /translation="MNKYEERYQENLSKNDFYKLINKSYLSDKELQVQQVKAGIVLPP
                     KAFETKLSNKLGLQKSLHGKGGVVDSNGNYIELSAQKAVGMRNRVYGPYKINYDNLPI
                     RNEKVIYLNYFIKQWGHFLLDVVGRLWYPLLQDNDTKLVYTCYAGTETKIEGNYLEFL
                     KLLGIDQSRLIMINCPTQFSEVIIPESSILPGGYYTKEYKQLFSSVVENIKLDKYDVN
                     AKMIYCSRSKLGIAKSKEFGEDGIEGIFKQNGYTSVYMETMSLEEQIKTLLSAKTIVL
                     TSGSLAHNLLFVNKDIDVFILNKTYRVNLHQFLINEISDATVRFVDIYRSPLPILYGY
                     GPFLMDLTKPLANFLDDNEFVYEKGTVLSKKDYFKYYLKWLWSYRFFLFRLNGIKEGN
                     SEFEKSFKIIRRYYKTGR"
     gene            10254..11639
                     /locus_tag="VQO19_000551"
     CDS             10254..11639
                     /locus_tag="VQO19_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000049683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HET1348855.1"
                     /translation="MSKYKELAKNTGIFALANFSSKILIFLLVPIYTRVLTTTEYGFY
                     DLVYTTIQLFVPILTLNISEAVMRFLMKDGVSKKSVFSIAVLDIFIGSIAFALLLLVN
                     NLFSLSDLISQYSIYIFVIFVFYTLNNFLIQFSKGIDKIGVTAISGVISTAVMLAMNV
                     ILLVVFDWGLLGFFIANVCGYVIPCIYIVSRLRLWELFEIKIDKKLQWEMVYYALPLV
                     LNILSWWVNNTSDRYIVTAIVGIQASAIISVAYKIPQILSTISAIFIQSWQISAIKIQ
                     EDKSDTTFVSNMLLYYNALLLIIASGIILFVKPISNILFGISFYSAWELVPFLIISSL
                     FNAISGCIGAIMGAKMDTHNIAKSALVGMIANIILNIVLTFLMGPQGITISTLIASFL
                     IFYMRKDSVKEINSETYRAIYLSWILLVVEACLLIYMDFIIGALIAMVINLFLLKDVI
                     KPLYLKIFKRN"
     gene            11647..12795
                     /locus_tag="VQO19_000552"
     CDS             11647..12795
                     /locus_tag="VQO19_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000636508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol--glycerophosphate
                     glycerophosphotransferase"
                     /protein_id="HET1348856.1"
                     /translation="MIVLQYFKILARFVFMFLISAVLLPFKIKPNKIVFINFNGKGYG
                     DNPKSICEYLRTTYPDLDLVWLARDNEGFPDGVRVVKYGTFQAFYEQASSKVWVYNVR
                     AFARILKKRGQIYIQTWHGASSFKLIEKQADLPINYVLEAKYDARVTDIMISDSRKQT
                     EEFQKYFWYSGEIFEVGMPRNDALFHYKEDYDKLNNIRKELSIHSDDYVILYAPTFRD
                     DGDASYLDINFERLLQCVEHGIKKKCKFLIRLHPNHSHLCNNISFNKNIINATFYSDM
                     QELTLLADVLVTDYSSSIFDFMLLNKPYVRYVNDLEKYAELRGVSDTYYELPDSIIKT
                     AEELYDLLPKKIENFDYDSIKKYRNEILCPIFNGTASENVGRRIIQEL"
     gene            12831..13859
                     /locus_tag="VQO19_000553"
     CDS             12831..13859
                     /locus_tag="VQO19_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HET1348857.1"
                     /translation="MKNNDLKIGSGAIHQISATLSQNSISGKILYCADPVVDDLYGSI
                     VRSQIEEIGRVKEESCNYNTIAYAMNIAERAIATDIDCIVGMGGGRVLDVCKYASFIS
                     KRPYLSIPTTAANDGIASPVAVLKRQDDRPKSLGAAIPSMTLIDIDVIASGPIQNIKA
                     GIGDTISNYTALKDWELAVERGKDEMHGFAYLMSQNSLDALMKTKYNSITPDFIEVLV
                     NSLVLSGIAMDFAGSSRPVSGSEHLFSHALDYYGSTRNLHGIQVALGTVAVLKLIENS
                     VDTVVDYLQRFEVHINPKLLGIDEELFIYCMQHATKMRSNRYTYLHEVDLSTDRLKQI
                     YKELISEL"
     gene            13875..14579
                     /locus_tag="VQO19_000554"
     CDS             13875..14579
                     /locus_tag="VQO19_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="HET1348858.1"
                     /translation="MKALILAAGLGTRLAPITNEVPKSLVPVNGKPILMKQIENLYQN
                     NITDITIIAGYKSSVLTDAVTEKYPEINIIDNVDFKTTNNMYSAYLGKAAMGDSDFLM
                     MNADVFYDASVIKSLLLHKAPNAIVTDLGIYIEESMKVVEKNGRLVEISKQISPEETL
                     GASIDVYKFSYEAGARFFEKCKEFIEDKRELQMWSEVALNAILSEVEFVACPLEGRWL
                     EIDNHEDLVAAEKLFA"
     gene            14594..15427
                     /locus_tag="VQO19_000555"
     CDS             14594..15427
                     /locus_tag="VQO19_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIA family hydrolase"
                     /protein_id="HET1348859.1"
                     /translation="MKLTNRVDYFGADISELQNKKLFLFDMDGTIYEEDRLFEGTLEL
                     LDYIHNIGGEYIFITNNSSKSVVDYVEKVNRLGIKAERDNFFTSAQATIVYIKENYPK
                     SKVYCQGTKSLIKELSDAGIDVTEQVSADIDVVLVGFDTELTSDKIRNTCEILSTKDV
                     PFIATNPDIRCPVSFGFIPDCGSICDMISKSVDRKPVYIGKPEPTMVDIVRKKLNYSL
                     FETVVIGDRLYTDIMTGINAGVTSVCVLTGEATVNDIQQDSIKPTYTFKNVKEMWKGI
                     V"
     gene            15587..16456
                     /gene="rfbA"
                     /locus_tag="VQO19_000556"
     CDS             15587..16456
                     /gene="rfbA"
                     /locus_tag="VQO19_000556"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HET1348860.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFKELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFIGDDSV
                     ALILGDNIYHGPGLSTMLQKAAKKEKGATVFGYHVKDPERFGVVEFDENMNAISIEEK
                     PEYPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRRGYISREDVLALAQSLKKN
                     EYGQYLLRLIGEA"
     gene            16457..17050
                     /locus_tag="VQO19_000557"
     CDS             16457..17050
                     /locus_tag="VQO19_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018029578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HET1348861.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKNHPLLKDVKPLKKEDL"
     gene            17063..18112
                     /gene="rfbB"
                     /locus_tag="VQO19_000558"
     CDS             17063..18112
                     /gene="rfbB"
                     /locus_tag="VQO19_000558"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HET1348862.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQAVD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            18178..19029
                     /gene="rfbD"
                     /locus_tag="VQO19_000559"
     CDS             18178..19029
                     /gene="rfbD"
                     /locus_tag="VQO19_000559"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HET1348863.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITDAEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGRELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            19092..20274
                     /gene="glf"
                     /locus_tag="VQO19_000560"
                     /pseudo
     CDS             19092..20274
                     /gene="glf"
                     /locus_tag="VQO19_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272499.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            20511..22493
                     /locus_tag="VQO19_000561"
     CDS             20511..22493
                     /locus_tag="VQO19_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET1348864.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVVIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDETTDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            22794..28097
                     /locus_tag="VQO19_000562"
     CDS             22794..28097
                     /locus_tag="VQO19_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET1348865.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVANKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTKNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKIRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKNVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPLYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIESLKNALVQKKTALVAED
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASEQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(28264..30423)
                     /locus_tag="VQO19_000563"
     CDS             complement(28264..30423)
                     /locus_tag="VQO19_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="HET1348866.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(30420..31016)
                     /gene="recU"
                     /locus_tag="VQO19_000564"
     CDS             complement(30420..31016)
                     /gene="recU"
                     /locus_tag="VQO19_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HET1348867.1"
                     /translation="MVNYPHKVSSQKRQKSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            31082..31609
                     /locus_tag="VQO19_000565"
     CDS             31082..31609
                     /locus_tag="VQO19_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HET1348868.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENEIKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            31679..32008
                     /gene="gpsB"
                     /locus_tag="VQO19_000566"
     CDS             31679..32008
                     /gene="gpsB"
                     /locus_tag="VQO19_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HET1348869.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            32029..32409
                     /gene="rnpB"
                     /locus_tag="VQO19_000567"
     ncRNA           32029..32409
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VQO19_000567"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            32494..33651
                     /locus_tag="VQO19_000568"
     CDS             32494..33651
                     /locus_tag="VQO19_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HET1348870.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            33664..35034
                     /gene="mapZ"
                     /locus_tag="VQO19_000569"
     CDS             33664..35034
                     /gene="mapZ"
                     /locus_tag="VQO19_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HET1348871.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEELVETQSLDDLIQEMREAVEESEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKSAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQASSNTTS
                     EPKPSSSNETRSSRSEVNMGLSSEGVAVQRSASRVAYNQSAIDDSNNSAWDFADGVLE
                     QILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGYFVGNGAGH
                     ADDLDY"
     gene            35110..36534
                     /gene="gndA"
                     /locus_tag="VQO19_000570"
     CDS             35110..36534
                     /gene="gndA"
                     /locus_tag="VQO19_000570"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HET1348872.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            36546..37235
                     /locus_tag="VQO19_000571"
     CDS             36546..37235
                     /locus_tag="VQO19_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET1348873.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            37333..38352
                     /gene="cbpC"
                     /locus_tag="VQO19_000572"
     CDS             37333..38352
                     /gene="cbpC"
                     /locus_tag="VQO19_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HET1348874.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPTTGIM
                     QTGWQYLGNKWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSS
                     GAMATGWYQDGSTWYYLNASNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYN
                     GEWVR"
     gene            complement(38470..39702)
                     /locus_tag="VQO19_000573"
     CDS             complement(38470..39702)
                     /locus_tag="VQO19_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET1348875.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVMSIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLAMLSIIIS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(39713..40165)
                     /locus_tag="VQO19_000574"
     CDS             complement(39713..40165)
                     /locus_tag="VQO19_000574"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348876.1"
                     /translation="MFYNDLHTFHTELKKLLEKVTSNTENLGNLQLSWCEGISGIILY
                     LCMYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKIQQVI
                     LACSERDDHGLLMFQGDSGKADLFDFGIGSMGVYWCLLNNKFPFDVQT"
     gene            complement(40233..40708)
                     /locus_tag="VQO19_000575"
                     /pseudo
     CDS             complement(40233..40708)
                     /locus_tag="VQO19_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
     gene            41233..41562
                     /locus_tag="VQO19_000576"
     CDS             41233..41562
                     /locus_tag="VQO19_000576"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET1348877.1"
                     /translation="MTRKAYDTDLNDQEWAKIEPYFCKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFHRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVR"
     gene            41684..42562
                     /gene="mvk"
                     /locus_tag="VQO19_000577"
     CDS             41684..42562
                     /gene="mvk"
                     /locus_tag="VQO19_000577"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HET1348878.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            42544..43497
                     /gene="mvaD"
                     /locus_tag="VQO19_000578"
     CDS             42544..43497
                     /gene="mvaD"
                     /locus_tag="VQO19_000578"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HET1348879.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            43484..44491
                     /locus_tag="VQO19_000579"
     CDS             43484..44491
                     /locus_tag="VQO19_000579"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HET1348880.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            44475..45485
                     /locus_tag="VQO19_000580"
     CDS             44475..45485
                     /locus_tag="VQO19_000580"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HET1348881.1"
                     /translation="MTTNRKDEHILYALEQKSSCNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            45562..46260
                     /locus_tag="VQO19_000581"
     CDS             45562..46260
                     /locus_tag="VQO19_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HET1348882.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            46257..47252
                     /locus_tag="VQO19_000582"
     CDS             46257..47252
                     /locus_tag="VQO19_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET1348883.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENQSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            47266..47898
                     /locus_tag="VQO19_000583"
     CDS             47266..47898
                     /locus_tag="VQO19_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET1348884.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            47899..48141
                     /locus_tag="VQO19_000584"
     CDS             47899..48141
                     /locus_tag="VQO19_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET1348885.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRILENTNMWLLTI"
     gene            48066..48377
                     /locus_tag="VQO19_000585"
     CDS             48066..48377
                     /locus_tag="VQO19_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET1348886.1"
                     /translation="MDWDFADTCWEKDPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSLWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            48402..48668
                     /locus_tag="VQO19_000586"
                     /pseudo
     CDS             48402..48668
                     /locus_tag="VQO19_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            48818..49057
                     /locus_tag="VQO19_000587"
     CDS             48818..49057
                     /locus_tag="VQO19_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348887.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            49138..49959
                     /gene="cbpG"
                     /locus_tag="VQO19_000588"
     CDS             49138..49959
                     /gene="cbpG"
                     /locus_tag="VQO19_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HET1348888.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVRYLKEFRNLNSKNAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYLSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSAVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYYYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNRAMVTGSQTIDGKVYNFASSGEWI"
     gene            49978..51000
                     /gene="cbpF"
                     /locus_tag="VQO19_000589"
     CDS             49978..51000
                     /gene="cbpF"
                     /locus_tag="VQO19_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HET1348889.1"
                     /translation="MKLFKKMMQVVLATFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRIEIALRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSPAEKRVYYFEDQRSYHTLKTGWI
                     YEEGHWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLDPATGI
                     MQTGWQYLGNKWYYLHSSGAMATGWYKEGSTWYYLDAENGDMRTGWQNLGNKWYYLRL
                     SGAMATGWYQEGSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGALAVNTTVGGYYLNY
                     NGEWVK"
     gene            complement(51128..52099)
                     /locus_tag="VQO19_000590"
                     /pseudo
     CDS             complement(51128..52099)
                     /locus_tag="VQO19_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        16413 a         8645 c        11288 g        15753 t
ORIGIN      
        1 ttaagaaata aggctacttt ttctgggtct tgttcataat tagattgaaa ctagaatagt
       61 acacatctgc ttctaaaaca ttgttagaaa acgatttgac tgtcctgaac aatttgtcat
      121 gttcttgttt cattttacta tatttttggt tcgcgggaag tctactaaga tacttaaaga
      181 tgcagatagt gaaaaaaagg tgtagacatt accgtaaaaa agtgatataa tcgtatgatg
      241 ttcaatgtat aggtgttaat catgagtaga cgttttaaaa aatcaggttc acagaaagtg
      301 aagcgaagtg ttaatatagt tttgttgact atttatttat tgttagtttg ttttttattg
      361 ttcttaatct ttaagtacaa tatccttgct tttagatatc ttaatctagt ggtaactgcg
      421 ttagtcctac tagttgcctt ggtagggcta cttctgatta tctataaaaa agctgaaaaa
      481 tttactattt ttctgttggt gttctctatc cttgtcagct ctgtgtcgct ctttgcagta
      541 cagcagtttg ttggactgac caatcgttta aatgcgactt ctaattactc agaatattca
      601 atcagtgtcg ctgttttagc agatagtgag atcgaaaatg ttacgcaact gacgagtgtg
      661 acagcaccga ctgggactga taatgaaaat attcaaaaac tactagctga tatcaagtca
      721 agtcagaata ccgatttgac ggtcgaccag agttcgtctt acttggcagc ttataagagt
      781 ttgattgcag gtgagactaa ggccattgtc ttaaatagtg tctttgaaaa tatcatcgag
      841 tcagagtatc cagactatgc atcgaagata aaaaagattt ataccaaggg atttactaaa
      901 aaagtagaag ctcctaagac gtctaagaat cagtctttca atatctatgt tagtggaatt
      961 gacacctatg gtcctattag ttcggtgtcg cgatcagatg tcaatatcct gatgactgtc
     1021 aatcgagata ccaagaaaat cctcttgacc acaacaccac gtgatgccta tgtaccaatc
     1081 gcagatggtg gaaataatca aaaagataaa ttaacccatg cgggcattta tggagttgat
     1141 tcgtccattc acaccttaga aaatctctat ggagtggata tcaattacta tgtgcgattg
     1201 aacttcactt ctttcttgaa aatgattgac ttattgggag gggtagatgt tcataatgat
     1261 caagagtttt cagctctaca tgggaagttc catttcccag tagggaatgt ccatctagac
     1321 tctgagcagg ctctaggttt tgtacgtgaa cgctactcac tagcagatgg cgatcgtgac
     1381 cgcgggcgca atcaacaaaa ggtgattgtg gctatccttc aaaaattaac gtcaaccgaa
     1441 gcactgaaaa attatagtac gatcattaat agcttgcaag attctatcca aacaaatatg
     1501 ccacttgaga ctatgataaa tttggtcaat gctcagttag aaagtggagg gaattataaa
     1561 gtaaattctc aagatttaaa aggtacaggt cggacggatc ttccttctta tgcaatgcca
     1621 gacagtaacc tctatgtgat ggaaatagat gatagtagtt tagctgtagt taaagcagct
     1681 atacaggatg tgatggaggg tagataaaat gatagacatc cattcgcata tcgtttttga
     1741 tgtagatgac ggtcccaagt caagagagga aagcaaggct ctcttgacag aatcctacag
     1801 gcagggggtg cgaaccattg tctctacctc tcaccgtcgc aagggcatgt ttgaaactcc
     1861 ggaagagaag atagcagaaa actttcttca ggttcgggaa attgcaaaag aagtagcaga
     1921 tgatttagtc attgcttatg gcgcagagat atactatact ctggatgctc tagaaaagct
     1981 agaaaaaaaa gaaattccta ccctcaatga tagtcgttat gccttgatag agtttagtat
     2041 gaacactcct tatcgcgata tccatagcgc cttgagcaag atcttgatgt tgggaattac
     2101 tccagtcatt gcccacattg agcgctatga tgctcttgaa aataacggaa aacgtgttcg
     2161 tgaactgatt gatatggggt gctatactca gataaatagt tatcatgttt caaaacctaa
     2221 gttctttggt gaaaaatata aattcatgaa aaagagagct cggtattttt tggaacgtga
     2281 tttagttcat gtagttgcaa gtgatatgca caatttagac agtagacctc catatatgca
     2341 acaggcatat gatatcattg ctaagaaata tggagcgaaa aaagcgaaag aactttttgt
     2401 agataatccc agaaaaatta taatggatca attaatttag gagaaaatat gaaggaacaa
     2461 aacactttgg aaatcgatgt attgcaacta ttcagagctt tatggaaaag aaagttggtc
     2521 attttattag tggcaattat aacttcttcg gttgctttta cctacagtac ttttgttatc
     2581 aaacctgagt ttactagtac gactcggatt tatgtagtta accgtaatca gggagagaag
     2641 tctggtttaa ccaatcaaga cttgcaggca ggaacatact tggttaaaga ctatcgtgaa
     2701 attatcctat cgcaggatgt tttggaggaa gttgtttctg atttgaaact agatttgacg
     2761 ccaaaaggtt tggctaataa aattaaagta acagtaccag ttgatacccg tattgtctct
     2821 gtttcagtta atgatcgagt tcctgaagag gcaagccgta tcgctaactc tttgagagaa
     2881 gtagctgctc aaaaaattat cagtattact cgtgtttctg atgtgacaac actggaggag
     2941 gcaagaccgg cgatatcccc gtcttcgcca aatattaaac gcaatatact aattggtttt
     3001 ttggcagggg tgattggaac tagtgttata gttcttcttc ttgaactttt agacactcgt
     3061 gtgaaacgtc cggaagatat cgaagataca ctgcagatga cacttttggg agttgtacca
     3121 aacttgaata agttgaaata ggagagagag atgccgacat tagaaatagc acaaaaaaaa
     3181 ctggagttca ttaagaaggc agaagaatat tacaatgcct tgtgtacaaa tatacagttg
     3241 agcggagata aactaaaagt aatttccgtt acttctgtta gccctgggga aggaaaaaca
     3301 actacttccg taaatatagc atggtcgttt gcgcgtgcag gctataaaac tcttttgatc
     3361 gatggcgata ctcgaaattc agttatatca ggatttttta aatctcgtga aaaaattaca
     3421 gggctaacag aatttttatc tgggacagct gatttatctc acggtttatg tgatacaaat
     3481 attgaaaatt tatttgtagt tcaatcggga tctgtatcac caaaccctac agccttgtta
     3541 caaagtaaaa attttaatga tatgattgaa acattgcgta aatattttga ttatatcatt
     3601 gttgatacag cacctattgg aattgttatt gatgcggcaa ttatcactca aaagtgtgat
     3661 gcgtccatct tggtaacagc aacaggtgag gcgaataaac gtgatgtcca aaaagcgaaa
     3721 caacaattaa aacaaacagg aaaactgttc ctaggggttg ttttaaataa attagatatc
     3781 tcggttgata agtatggagt ttacggtttc tatggaaatt atggtaaaaa ataatttagg
     3841 aaagattcta tggatgaaaa aggattgaaa atttttatgg cagtattaca gagtattatt
     3901 gtcattttat tggtttattt tcttagcttt gttagagaga cagaacttga acgttcttcg
     3961 atggttatac tataccttct ccactttttt gtattctatg ttagttccta tggtaacaat
     4021 ttttttaaaa gagggtacct agttgagttt aatagtacta taagatatat ttttttcttt
     4081 gcaatagcta taagtgtatt aaactttttt atagcggaac ggtttagtat ctctagaaga
     4141 ggaatggtat acttcttaac tttagaagga atatccttat acttgttaaa tttcttagta
     4201 aagaaatatt ggaaacatgt gttttttaat ctaaaaaata gcaagaaaat tttactgtta
     4261 acagtaacga aaaatatgga aaaagttctt gataaattgc tagaatctga tgaactttca
     4321 tggaagttgg tagcagtaag tgttttgaat aaatctgatt ttcaacatga taaaatacct
     4381 gtaattgaaa aggaaaaaat tattgaattt gcaacgcatg aagttgtgga tgaggtgttt
     4441 gtcaatcttc caggagagag ctacgatatt ggagaaatta tctctaggtt tgagacaatg
     4501 gggatagatg taactgtaaa tcttaaagca tttgataaga atttgggtcg caataaacaa
     4561 attcatgaga tggtaggatt gaatgtagtc actttctcta caaattttta taaaactagt
     4621 catgtgattt caaagagaat tctcgatatt tgtggtgcca ctattggcct tattcttttt
     4681 gctatagcta gtctagtttt agttccattg attcgtaaag atggcggacc agctattttt
     4741 gctcaaactc gtatagggaa aaatggtcga cattttacct tttataaatt ccgttcgatg
     4801 aggatcgatg ctgaagctat caaagaacag ttgatggatc aaaatacgat gcaaggtggt
     4861 atgtttaaga tagacaatga tcctcgtgtt acaaaaattg gtcgctttat tcgtaaaacc
     4921 agtttagatg aattgccgca gttttggaat gtctttatag gagatatgag tttggtggga
     4981 acacgtccac ctacagtaga cgagtatgat cagtatactc cagaacaaaa acgtcgactc
     5041 agctttaaac ctggtattac aggtttatgg caggttagcg gccgtagtaa aataaccgat
     5101 tttgacgatg ttgtaaaatt agatgtgtct tatattgata attggacaat ctggaaagat
     5161 attgaaattt tgcttaaaac tgttaaagtt gtatttatga gagatggagc gaagtaattt
     5221 ctgtatatcc atcatattag gagagaaatg aaaaagtcag tttatatcat tggttcaaaa
     5281 ggaattcctg ctaagtatgg aggatttgaa acttttgttg aaaaattaac agccttccaa
     5341 caagataagg ctatccaata ttatgtggct tgtatgcgtg aaaactctgc aaaatcaggg
     5401 actactgagg atgtttttga acataatggt gctatctgtt ataacgtcga tgttcctaat
     5461 attggtccag cgcgagccat agtatatgat atcgcggcaa ttaacagagc tattgaaatt
     5521 gccaaagaaa ataaggatga agatccaatc ttctatattt tagcttgtcg aatcggtccg
     5581 ttcatccatg gaattaagaa aaaaatccag gcgataggtg ggactcttct agttaatcca
     5641 gatggtcacg agtggttacg agctaagtgg agcactccag ttcgtcgtta ttggaaaatt
     5701 tccgaaggtc ttatggtcaa acatgcagat ttattggttt gtgacagtaa aaatatcgaa
     5761 cagtatatcc aagaagatta taaacagttc caacctaaga ccacctatat cgcttatggg
     5821 accgatacaa cacgctccat attaaagagt agtgatgaaa aagtacgttc ttggttcaaa
     5881 gagaagaatg tttctgagaa cgagtattat ctagttgtag gacgatttgt tccagagaat
     5941 aactatgaat ctatgattct tggcttcttg gcttctaact ctaagaagga ctttgtttta
     6001 attacaaatg tagaacagaa taaattttat aatcagttgt tggcaaaaac tggttttgat
     6061 aaagatccac gagtaaaatt tgtagggaca gtctacaacc aagagcttct aaagtatatt
     6121 cgagaaaatg cttttgctta cttccacggg catgaagttg gtggaacaaa tccttcgtta
     6181 cttgaagcat tagcatccac aaagttaaac ttactactcg atgttggctt taaccgagaa
     6241 gtagctgagg atggtgctga ttactgggaa aaagataatc ttcataaggt tattgaagcg
     6301 agtgaacaaa aaacacaaga agagataaat gaaaaaaata tactgtcaac aaagcaagtg
     6361 acggagcgct tctcttggga tttgatagtt aatgagtatg agaaactttt tacgagaaaa
     6421 aactagaaac tcataaggga ttatttgaat aaataagttt ttgctttttc tcattgatag
     6481 aacaataaga ttgctttagt aaataataat tagaaaactg tatataaaat ttcataatat
     6541 ggaaaatgag tttcgaagag aagagtacat atgtcatgaa tgtagtaatt gataacagaa
     6601 aattaggggg gataagttga aagtagatat gatttttgag gtacggaata atgagaatta
     6661 gttttagtaa aaaaactatg ctgtgtggtt tattgtatat tggtttaatt ttatccgtag
     6721 taacaatacc tacaattgta acatttttat attctttgct attcatcggg attgtaacag
     6781 tcttaaatta taattctatt ctagcaagtg acgaagatgc gaactctttt tttgttgcat
     6841 tacctattat tttatcttct tttcaaaatg tatatttggg atttggagcg gatcgattaa
     6901 attctgtcac actacaagtt ctgctatcta ttagcattgc tattattaca attacagttt
     6961 ttctaggtat tatcttaaat agattcaaat caaaagaatt tagttggtta gttttaagta
     7021 ttcttgtaat tataattcaa tcagtaattc ttttaatatt ctttcccact accttgccag
     7081 catatttatc atctatgaga aatatactag ccccactact gattttttat ttttctatct
     7141 atgggtttaa aaatattaat ttacaaaaat tttataaata tatgttcata attatattag
     7201 ttgttctaat ttttggattt attgagtata tatacggaaa tagtttatgg acaagattga
     7261 atattaaaaa gctttgggct ttgaaggggc tggcgattga gaatagggtt gttcctggga
     7321 attggcactc ttctgaatta attggcggta aacaattaag gcgtatggtt tcaacatttg
     7381 ccgatcccgt aaatctaggt tcgtatctct ttgcggcatt tatgttagct tggtacaaaa
     7441 ataagaaact acttcaagtt ttattgctcg cttcttttgt actcagtgta agtaaagcag
     7501 cgtttttaag catgttggta tatataataa tttatacctg ggttgtggat aaaaataaaa
     7561 ttttatcgat ttttggaata ataatttcaa ctgtattggg gttgtatttt tataatttta
     7621 gtcaagttag tagttatggt agtataaatg cacatatcga tggttttttt agtgcgttaa
     7681 gtactcccct ccattaccca tttggtatgg gagtagggag tgtgggagtt ctagcttcaa
     7741 aattaggttc acaaacagca ctttcttcag aggttttaga aacaggaatt ggaatgataa
     7801 ttgctcaatt aggattcgtg ggtgtgataa tatatttgat tttctttgta aaactctccg
     7861 taataggaaa gaatattaat aataaaagag ataaaatttt atggtttact ttaatttata
     7921 gctttttggc taatgccttt tttaacgagg ttgcactttc tcctaactca tgcaccttat
     7981 attttttaat tttaggactg ctttataata aaaataaaat tagaagcaca gagtttagtt
     8041 aatggaaaaa ttagttagta ttattctgcc cgtctacaat gtcgaacagt atataaaaaa
     8101 ttgtttagaa tcaattcaac aacaaactta tccaaatttg gaagtaatca ttgttaatga
     8161 cggttcaacc gataaaagcg ttgaatattg tgagcaaatt tgtaagatag attctaggtt
     8221 ttctatcact cacaaagaaa atggtggact ttccgatgca agaaatgtcg gtatagataa
     8281 agccaaggga gattacctca tttttgttga cagtgatgat tttgtttctc aagatatggt
     8341 atcttattta gtatcttgta tggagaacaa tgaggcagac attgctattt gcgatcctgt
     8401 tcattattat agtgatcgtc aaaacaatga tcttaatatt ttttctccag catcaagcgt
     8461 taaggtttac gaaacaacgg aggctctatg tgagatgttt tatcaaaaat cttttttggt
     8521 gtctgcctgg gccaagatat ttaaaagaga gttgtttgat gatataagat ttcctgtagg
     8581 taagctattt gaagatagtg cgattatgta tttgctcctc gaaaaatgtg aaacaattgc
     8641 atactctgat gcgaaattat atgcttatgt acacagggat aatagtatca caacaaagaa
     8701 attttcggat agagacttag atattttgga gattacgaac acaattatta atcactatgg
     8761 tgataattta cgcgtgtata ctgcagcggt gtcttataag gtatctgcat gtttcagaat
     8821 tctattaaac tcaccttctg aagaaaagta taaaaaagta caaaaagaat gtctgagtta
     8881 tattttacaa aattggagaa acatattatt taataataat gttcgattga agaacaagct
     8941 tgccttaatt tctataacta ttttcaatcc ttttgttaaa tttatctata gcaaagtaaa
     9001 cagatgggaa tgatagcaaa tgaacaaata tgaagaaaga tatcaagaaa atttatctaa
     9061 gaatgatttt tataaattaa ttaataagag ttacttatca gataaagaac ttcaagtaca
     9121 acaagtaaaa gctgggatag tcttaccacc aaaggcattt gaaacaaaat tatcaaataa
     9181 acttggccta caaaaatctt tgcatggaaa gggtggagtt gtagactcaa atggaaatta
     9241 cattgaacta tctgcacaaa aagcagtcgg gatgagaaat agagtctatg gtccgtataa
     9301 aattaattac gacaatctgc caattagaaa tgaaaaagta atctatttga actatttcat
     9361 caaacaatgg ggacattttt tactggatgt tgttggaagg ttatggtatc cattgctgca
     9421 ggataatgat actaagttag tctatacctg ctatgctgga acagaaacaa agattgaggg
     9481 aaactattta gagtttttga agcttctcgg catagatcaa tcacgtttaa tcatgataaa
     9541 ctgtcccact cagttctcag aagtcattat tcctgaaagc tccattttac cggggggata
     9601 ttatacaaaa gagtataaac aactattcag ttcggtagta gaaaatatta aattggacaa
     9661 gtatgatgtg aatgctaaaa tgatttattg ttcgaggtct aaattaggga ttgctaaaag
     9721 taaagaattt ggcgaagacg gtattgaggg gatttttaaa caaaatggct acacatctgt
     9781 ttacatggaa acaatgtctt tggaagagca aataaaaacc ttattatcgg ctaagacaat
     9841 agtattaacg agtggttcgt tagcacataa tcttttattt gtaaataaag atattgatgt
     9901 ttttattttg aataaaacct atagagtaaa tctccatcaa tttttaataa acgagatctc
     9961 agatgctaca gtaagatttg tagatatcta tcgatcacct ttaccgattt tatacggata
    10021 tggaccattt ttaatggatc ttacaaaacc tttggctaat ttcttggacg ataatgaatt
    10081 tgtatatgaa aaaggtactg ttttaagtaa aaaagattat tttaaatact atttgaaatg
    10141 gttgtggagt tatagattct ttttatttag gttaaatggt attaaagaag gaaatagtga
    10201 attcgagaag agttttaaga taattaggag atactataaa acaggacgat agaatgagta
    10261 aatataagga attagcaaaa aatacaggta tttttgcttt ggctaacttt tcatcaaaga
    10321 ttttaatttt tttgttagta cctatatata cacgggtact taccactacg gaatatggtt
    10381 tttatgactt agtctataca actattcagc tttttgtacc aatcttgaca ttaaatatat
    10441 ctgaagccgt tatgaggttc ctaatgaaag atggtgtttc taaaaaatca gtcttttcaa
    10501 ttgctgtttt agatatattt attggatcaa ttgcttttgc tttattgttg ttagtaaata
    10561 acctgttttc tttatcagat ttaatttctc aatacagtat ttacatattt gtaatctttg
    10621 ttttctatac cctaaataat tttttgatac aattttctaa gggaattgat aaaattggtg
    10681 ttacagctat ctctggggtc ataagtacag cagttatgct tgccatgaat gtcattcttc
    10741 tagtagtatt tgattgggga ttgttaggtt tctttattgc taatgtttgt ggatatgtta
    10801 taccttgtat ttatatagtt tctagattaa gattgtggga attatttgaa attaagattg
    10861 ataaaaaatt acaatgggaa atggtttact atgctttgcc attagtttta aatatattaa
    10921 gctggtgggt aaataatact tcagatagat atattgtgac tgcaatagta ggtatacaag
    10981 ctagtgcaat tatttcagtc gcttataaaa ttccacagat tttgtctacg attagtgcaa
    11041 tttttattca atcatggcaa atctctgcaa ttaaaataca agaagataag agcgatacta
    11101 catttgtatc aaacatgctc ctatactata atgcacttct attgattata gcgagtggta
    11161 tcatattatt tgtcaaacct atttctaata tattgtttgg tatttccttc tattctgcgt
    11221 gggagctggt accattttta ataattagca gtctattcaa tgcaatttca ggttgtatag
    11281 gagcaattat gggagctaaa atggatactc ataacattgc aaagtcggct ttagttggga
    11341 tgattgcaaa tattatttta aatatagtgt taacattctt aatgggtcca cagggaatta
    11401 caatttctac cctgatagct agttttctta ttttttatat gcgaaaagat agtgtaaaag
    11461 aaattaattc agaaacatat agagcaattt atttatcgtg gatactatta gttgtagagg
    11521 cctgtctgct aatttatatg gattttatta ttggtgcttt aatagcaatg gtaataaact
    11581 tatttttact aaaagatgtt atcaaacctt tatatttaaa aattttcaaa agaaattagg
    11641 tacaaaatga ttgttttaca atactttaag attttagcta gattcgtttt tatgtttttg
    11701 ataagtgcgg tgttactgcc tttcaaaata aaacctaata agattgtttt tattaatttc
    11761 aatgggaaag gatatggtga taatccgaaa agtatttgtg agtatcttag aactacttac
    11821 ccagatttag atttggtttg gcttgcaaga gataacgaag gttttccaga tggggttagg
    11881 gttgttaaat atgggacttt ccaagctttt tatgagcaag cgagttcgaa ggtttgggta
    11941 tataatgtaa gagcttttgc aagaatacta aaaaaacgag gacagattta tattcaaact
    12001 tggcatggtg cttctagttt taagttgata gaaaaacaag ctgatttacc aataaattat
    12061 gttttagaag ctaagtatga tgcaagagtc acagatataa tgatttcaga tagcagaaaa
    12121 caaactgaag aatttcaaaa gtatttttgg tattcaggag aaatttttga ggtggggatg
    12181 ccgagaaatg atgccttgtt tcactataag gaagactacg acaagttaaa taatatcaga
    12241 aaagaactaa gcattcattc agatgattat gttattttat atgcccctac tttcagagat
    12301 gatggggatg catcttattt agatataaat tttgaacggc ttttgcaatg tgttgaacac
    12361 ggaattaaaa agaaatgtaa attcttaatt aggttacacc ctaatcactc ccatttgtgt
    12421 aataatattt catttaataa gaatataatc aatgctacgt tttattcaga tatgcaagag
    12481 cttactttgt tggcagatgt tttagtcaca gattattctt cctcgatatt tgattttatg
    12541 cttttaaaca agccttatgt cagatatgtg aatgatttag aaaaatatgc tgagcttagg
    12601 ggggtatcag atacatatta cgaattgccg gattcgatta ttaaaactgc tgaagaattg
    12661 tatgacttac tgcctaaaaa aatagaaaat tttgattatg attctataaa aaaatataga
    12721 aatgaaatac tgtgtccaat ctttaatgga accgctagtg aaaatgtagg aaggagaata
    12781 attcaagagt tgtgaagtaa aacattgggt tatttttaag gtaacgagat ttgaaaaata
    12841 atgatttaaa gataggaagt ggagctattc atcaaatttc cgctacactt tctcaaaata
    12901 gtatttcggg aaagatttta tattgtgctg atccagttgt cgatgacttg tacggttcga
    12961 tagtacgttc acaaatagag gaaattggtc gggtaaagga agaaagttgc aattataata
    13021 ctattgctta tgcgatgaat atagcagaac gggctattgc cacagatatt gactgtattg
    13081 tgggaatggg aggaggtcgt gttttagatg tctgcaagta tgcatctttt atttcgaaac
    13141 gtccttacct atcgattccg acaacagcag caaatgatgg cattgcttcc ccagttgctg
    13201 ttttgaaaag gcaggatgat agaccaaaaa gcttaggggc ggctatcccc tcaatgacac
    13261 taattgatat tgatgttatt gcatcaggac ctatacaaaa tataaaagct ggtatcggtg
    13321 atacaatatc caattacact gcattgaaag attgggagtt ggcagttgag cgagggaaag
    13381 atgagatgca tggttttgca tatctaatgt cgcaaaattc tttagatgct ttaatgaaaa
    13441 cgaagtataa ttctattacc cctgatttta ttgaagtttt ggtaaactct ttagttttat
    13501 caggcattgc aatggatttt gcgggaagta gtagacctgt cagtgggtca gagcacttat
    13561 ttagtcatgc attagattac tatggttcta caaggaatct tcatggaatt caggttgcat
    13621 taggtacagt cgcagttttg aaattaattg aaaattctgt tgatactgta gtggattact
    13681 tgcaaagatt tgaggttcat attaacccga aacttttggg gatagatgaa gagttgttta
    13741 tttattgtat gcaacatgct acaaaaatga gaagtaatcg ctatacctat ctgcatgaag
    13801 ttgatcttag cacagataga ttgaaacaaa tatataagga actcataagc gagttgtaga
    13861 aaagagagga aaaaatgaaa gcacttattt tagcagcagg gttaggaaca cgtctagctc
    13921 caattaccaa tgaggtacca aaatctttgg taccagtcaa tggtaagcca attttgatga
    13981 aacaaattga aaatttatat caaaataata ttacagatat tacgattatt gctggatata
    14041 agtcatctgt attaacagat gcagttactg aaaagtatcc agaaattaat attattgata
    14101 atgttgattt taaaacgact aataatatgt attcagccta tctaggaaaa gctgcaatgg
    14161 gtgatagtga cttcttaatg atgaatgcag atgtatttta tgatgcttct gttattaaaa
    14221 gtctgttgct tcataaagct ccaaatgcaa ttgtaactga tttaggtatt tatattgaag
    14281 agtctatgaa agtcgtagaa aaaaatggtc gtttagtaga aatttctaaa cagatttcac
    14341 ctgaggaaac tttaggagct tctattgatg tttataaatt ctcttatgaa gcaggtgctc
    14401 gattctttga aaagtgtaag gaatttattg aagataaacg agaacttcaa atgtggagtg
    14461 aggttgctct taatgcaatt ctttctgaag ttgaatttgt agcatgtcca ttagagggtc
    14521 gttggttaga aattgataat catgaagact tagttgctgc agaaaaacta tttgcttgaa
    14581 ccgaatacgg agaatgaaat tgacaaatag agttgattat tttggtgctg atattagtga
    14641 acttcagaat aaaaaattat tcttatttga tatggatggt accatttatg aagaagatag
    14701 gttgtttgag ggtactctcg aattattaga ctatattcat aatattggcg gtgagtatat
    14761 ttttattaca aacaattcat ctaagtctgt tgttgactat gttgaaaaag ttaacagatt
    14821 aggtattaaa gctgaacgag ataatttttt tacctctgct caagccacaa ttgtttatat
    14881 taaagaaaat tatcctaaat ctaaagttta ttgccaagga acaaaatctt tgataaaaga
    14941 actatctgac gcaggaattg atgtaactga gcaagttagt gctgatatag atgttgttct
    15001 tgttggtttt gatacagaat taaccagtga taaaattcgc aatacctgcg agattctatc
    15061 aacaaaggac gtacctttca tagctactaa ccctgatatt cgctgcccag tatcgtttgg
    15121 attcatcccg gattgtggtt ccatttgtga tatgattagt aaatcagtcg ataggaaacc
    15181 tgtttacata ggtaaacctg aacctacgat ggttgatatt gttcgaaaaa aattaaatta
    15241 ttctctattt gaaacagttg tgattggaga tcgcttgtat acggatatca tgactggtat
    15301 aaatgcagga gtaacttcag tttgtgtgct gacaggagaa gcaacggtga atgatattca
    15361 acaagatagt ataaaaccga cttatacatt taaaaacgtg aaagaaatgt ggaaaggaat
    15421 tgtctgattt tttcattctg aatagtgaat tcatgaatac tgtcaaaata ctcgtatgta
    15481 tttaaattga ttttattatt ttaataatgg acaaattaaa attatttttc tccccaaatc
    15541 gttcgtgaac gtaaagtact catcaacaaa gaaaggtacc ccttttatga aaggtattat
    15601 tctagcaggt ggttcgggaa ctcgcttgta tcctttgact cgcgctgcat caaaacaact
    15661 tatgccggtt tatgataaac cgatgattta ctacccactt tcaacattaa tgttggctgg
    15721 gattagggat attttgatta tctcaactcc tcaagatttg cctcgtttta aagagcttct
    15781 tcaagatggt tctgagtttg gtattaaact ttcttatgct gagcaaccaa gtccagatgg
    15841 tttggcacaa gcctttatca ttggggaaga gtttatcggt gacgatagcg ttgccttgat
    15901 tttaggtgac aatatctacc atggtcctgg tctgagcaca atgcttcaaa aagcagccaa
    15961 gaaagagaaa ggtgcgactg tttttggcta ccatgtcaag gatccagaac gctttggtgt
    16021 tgtagaattt gatgaaaata tgaatgctat ctccatcgaa gaaaagccag aataccctcg
    16081 ttcaaactat gcagtgacag gactctattt ctatgataat gatgtagtag agattgccaa
    16141 aagtattaaa ccaagtcctc gtggtgaatt ggaaattaca gatgtcaaca aggcttactt
    16201 ggatcgtggt gatttgtctg ttgagctcat gggacgtggt tttgcttggt tggatactgg
    16261 cactcatgaa agtttactag aggcttcgca gtacatcgaa acagtccaac ggatgcaaaa
    16321 tgttcaggta gcaaacttag aagaaattgc ttaccgtagg ggctatatca gtcgagaaga
    16381 tgtattggcc ttagcccaat cacttaagaa aaatgaatac ggacagtatc tgctccgttt
    16441 gattggagaa gcatagatga cagataattt tttcggtaag acgcttgcgg cacgcaaggt
    16501 tgaagctatt ccaggcatgt tggagtttga tatccccgtt catggagata atcgtggctg
    16561 gtttaaagaa aatttccaaa aggaaaaaat gcttccactt ggatttccag agtctttctt
    16621 tgcagaagga aaattgcaaa acaatgtatc cttctcacgt aaaaatgtcc ttcgaggcct
    16681 ccacgcagag ccttgggata agtacatctc tgtagcagat ggagggaaag ttctgggttc
    16741 ttgggttgat ctacgcgagg gtgaaacctt tgggaatacc tatcagacag tgattgatgc
    16801 gagtaaggga atctttgttc ctcgaggcgt agctaatggc ttccaagttt tatcagatac
    16861 agtgtcatat agctatctgg tcaatgatta ctgggctctt gaactcaaac ccaagtatgc
    16921 ctttgtgaac tacgctgatc caagccttgg tattgaatgg gaaaatattg cagaagcaga
    16981 ggtttcagaa gcagataaaa atcatccact acttaaggat gtaaaacctt tgaaaaaaga
    17041 agatttgtaa aaaggaaaga atatgactga atacaaaaat attatcgtga caggtggagc
    17101 tggctttatc ggttctaact ttgtccatta tgtttacgag aactttccag atgttcatgt
    17161 gacagtccta gataagttga cttatgctgg aaaccgcgcg aatattgagg aaattttagg
    17221 taatcgtgtt gagttagttg ttggtgacat tgctgatgcg gagttggtag acaagttggc
    17281 tgctcaagca gatgctatcg ttcattatgc agcggaaagc cacaatgata attcgctcaa
    17341 tgatccatcg ccatttattc atactaactt catcggaacc tatactcttt tagaagctgc
    17401 tcgtaagtat gatattcgct tccaccatgt atcgacagat gaagtttatg gggatctccc
    17461 tttacgcgaa gatttgccag gtcatggtga aggaccaggt gagaaattta ctgctgaaac
    17521 aaaatacaac ccaagctctc cgtactcatc aaccaaggca gcctcagatt tgattgtcaa
    17581 agcctgggtg cgttcttttg gagtcaaggc aacgatttcc aactgttcaa ataactacgg
    17641 tccttatcaa catatcgaaa aattcatccc acgtcagatt actaacatcc taagtggaat
    17701 taagccaaaa ctttacggtg aaggtaagaa tgttcgtgac tggattcata ccaatgacca
    17761 ttcttcagga gtttggacaa tcttgacaaa agggcaaatc ggtgaaacct acttgattgg
    17821 ggctgatggt gagaagaaca ataaggaagt tttggaactt atccttaagg aaatgggaca
    17881 agctgtggat gcctatgatc atgtgactga ccgtgcagga catgaccttc gctatgcgat
    17941 tgatgctagc aagctccgtg atgagttggg gtggaaacct gaatttacca actttgaagc
    18001 tgggctcaag gcaacaatca agtggtatac agataaccaa gaatggtgga aagcagaaaa
    18061 agaagctgtt gaagccaatt atgctaagac tcaggagatt attacagtat aaaaagcagg
    18121 aaatagctgc tttttattgc tatattggga agagttacat attagaaagg tctagagatg
    18181 attttaatta caggggcaaa tggccaatta ggaacggaac ttcgctattt attggatgaa
    18241 cgtaatgaag aatacgtggc agtagatgtg gctgagatgg acattaccga tgcagaaatg
    18301 gttgagaaag tttttgaaga ggtgaaaccg actttagtct accactgtgc agcctacacc
    18361 gctgttgatg cagcagagga tgaaggaaga gagttggact tcgccatcaa tgtgacgggg
    18421 acaaaaaatg tcgcaaaagc atctgaaaag catggtgcaa ctctagttta tatttctacg
    18481 gactatgtct ttgatggtaa gaaaccagtt ggacaagagt gggaagttga tgaccgacca
    18541 gatccacaga cagaatatgg ccgtactaag cgtatggggg aagagttagt tgagaagcat
    18601 gtgtctaatt tctatattat ccgtactgcc tgggtatttg gaaattatgg caaaaacttc
    18661 gtttttacca tgcaaaatct tgcgaaaact cataagactt taacagttgt aaatgaccag
    18721 tacggtcgtc cgacttggac tcgtaccttg gctgagttca tgacctacct agctgaaaat
    18781 cgtaaggaat ttggttatta tcatttgtca aatgatgcga cagaagacac aacatggtat
    18841 gattttgcag ttgaaatttt gaaagataca gatgtcgaag tcaagccagt agattccagt
    18901 caatttccag ccaaagctaa acgtccgcta aactcaacga tgagcctggc caaagccaaa
    18961 gctactggat ttgttattcc aacttggcaa gatgcattgc aagaatttta caaacaagaa
    19021 gtgagataag tagtagaatg attttctagt ctaataaaag aggcagataa tgaactccaa
    19081 aggagcataa gatgtacgat tatcttatcg ttggtgccgg tctttttggt gcagtatttg
    19141 cccatgaatc agccttaaaa ggaaaaaaag taaaagttat tgaaaaacga aatcatattg
    19201 cgggtaatat ctatactcgt gaagaggaag gaattcaagt tcatcagtat ggtgctcata
    19261 tctttcatac ttctgataag gagatctggg attatgtgaa tcagtttgca gagtttaacc
    19321 gttataccaa ttctcctgtt gcaaactata ggggagatat ttataactta ccttttaata
    19381 tgaatacctt caataaactc tggggagttg tgacgccagc agaagcataa gctaagattg
    19441 atgaacaacg tgctatttta aatggtaaaa ctcctgaaaa tttggaagaa caggcgattt
    19501 ctcttgtagg tacagacatc tacgaaaaat taatcaaaga ctatacagag aaacagtggg
    19561 gcaaaccaac tactgaactt ccatccttta ttattcgccg tttaccagta cacctgacct
    19621 atgataacaa ctattttaac gatacctatc aagggattcc aattggtggt tataatgtta
    19681 tcatcgaaaa tatgctgaag gatgtagaag tagaacttgg agtgaacttt tttgccaatc
    19741 gtcaagaatt agaggcttct gctgaaaagg ttgtctttac agggatgatt gaccaatact
    19801 ttgattataa acatggtgag ttagaatact gtagtcttcg ttttgatcat gaagttctag
    19861 atgaggaaaa ctatcaagga aacgcagttg tgaactatac ggatgcagaa accccatata
    19921 ctcgcattat tgaacacaaa cattttgagt ttgggagtca agcaaagact atcattacta
    19981 atagaacatt ctaaaacatg ggaaaaaggt gatgagcctt attatccagt taataatgat
    20041 cgtaataatc atttgtataa atcatataaa aaacttgctg atgagcaagg gaatgttatc
    20101 tttggtggcc gcttaggaca ctatcgttat tacgatatgc accaagtaat tggagcagct
    20161 ttgcagtgcg tgagaaatga gttagattca tactcaatga aaatcaaaga gcaaactagg
    20221 aagctagccg caggttgctc aaaacactgt tttgaggttg cagatggaag ctgacgcggt
    20281 ttgaagagat tttcgaagag tataaacaag taaaactgac taccagttat tatttagaaa
    20341 tagtattaaa aattccttga ctatgtgata tagttgaggg atttttaaat gatattcata
    20401 ttttttgcaa agatgttgtt tgaaaaataa ttttcaaaaa ttctgaaaat tctgttgaca
    20461 actttctgaa aagagtctat aatggagaga aagttttaaa ggagaaaatg atgaaaagtt
    20521 caaaactatt tgcccttgcg ggcgtgacat tattggcggc gactacttta gctgcatgct
    20581 ctggatcagg ttcaagcact aaaggtgaga agacattctc atacatttat gagacagacc
    20641 ctgataacct caactatttg acaactgcta aggctgcgac agcaaatatt accagtaacg
    20701 tggttgatgg tttgctagaa aatgatcgct acgggaactt tgtgccgtct atggctgagg
    20761 attggtctgt atccaaggat ggattgactt acacttatac tatccgtaag gatgcaaaat
    20821 ggtatacttc tgaaggtgaa gaatacgcgg cagtcaaagc tcaagacttt gtaacaggat
    20881 taaaatatgc tgctgataaa aaatcagatg ctctttacct tgttcaagaa tcaatcaaag
    20941 ggttggatgc ctatgtaaaa ggggaaatca aagatttctc acaagtagga attaaggctc
    21001 tggatgaaca gacagttcag tacactttga acaaaccaga aagcttctgg aattctaaga
    21061 caaccatggg tgtgcttgcg ccagttaatg aagagttttt gaactcaaaa ggggatgatt
    21121 ttgccaaagc gacggaccca agtagtctct tgtataacgg tccttatttg ttgaaatcca
    21181 ttgtgaccaa atcttctgtt gaatttgcga aaaatccgaa ctactgggat aaggacaatg
    21241 tgcatattga caaagttaaa ttgtcattct gggatggtca agataccagc aaacctgcag
    21301 aaaactttaa agatggtagc cttacagcag ctcgtctcta tccaacaagt gcaagtttcg
    21361 cagagcttga gaagagtatg aaggacaata ttgtctatac tcagcaagac tctattacgt
    21421 atctagttgg tacaaatatt gaccgtcagt cctataaata cacatctaag accagcgacg
    21481 aacaaaaggc atcgactaaa aaggctctct taaacaagga tttccgtcag gctattgcct
    21541 ttggttttga tcgtacagcc tatgcctctc agttgaatgg acaaactgga gcaagcaaaa
    21601 tcttacgtaa tctctttgtg ccaccaacat ttgttcaagc agatggtaaa aactttggcg
    21661 atatggtcaa agagaaattg gtcacttatg gggatgaatg gaaggatgtt aatcttgcag
    21721 attctcagga tggtctttac aatccagaaa aagccaaggc tgaatttgct aaagctaaat
    21781 cagccttaca agcagaaggt gtgacattcc caattcattt ggatatgcca gttgaccaaa
    21841 cagcaactac aaaagttcag cgcgtccaat ctatgaaaca atccttggaa gcaactttag
    21901 gagcggataa tgtagtcatt gatattcaac aactacaaaa agacgaagta aacaatatta
    21961 catattttgc tgaaaatgct gctggcgaag actgggattt atcagataat gtcggttggg
    22021 gtccagactt tgccgatcca tcaacctacc ttgatatcat caaaccatct gtaggagaaa
    22081 gtactaaaac atatttaggg tttgactcag gggaagataa tgtagctgct aaaaaagtag
    22141 gtctatatga ctacgaaaaa ttggttactg aggctggtga tgagactaca gatgttgcta
    22201 aacgctatga taaatacgct gcagcccaag cttggttgac agatagtgct ttgattattc
    22261 caactacatc tcgtacaggg cgtccaatct tgtctaagat ggtaccattt acaataccat
    22321 ttgcattgtc aggaaataaa ggtacaagtg aaccagtctt gtataaatat ttggaacttc
    22381 aagacaaggc agtcactgta gatgaatacc aaaaagctca ggaaaaatgg atgaaagaaa
    22441 aagaagagtc taataaaaag gctcaagaag atctcgcaaa acatgtgaaa taactgttgc
    22501 aaaatataag aaaggattta gtatttctct tgaatgctga atcctttttt acatttgtaa
    22561 agaaagattc taaatgtact gacccccaaa agttggagcc tctttttgtc agaatagaga
    22621 aaatttttgt taattttact tgtttcctat tgctttctca gctattattt gttatattaa
    22681 aagtataatt attttttatt tatcagggtt aagcattgca ctttcagagg aaggagtatt
    22741 ttttaaaaag aaaatgtaaa cgcttgctca aaaatgaaag gatttagaag tttatgaata
    22801 aaggattatt tgaaaaacgt tgtaaatata gtattcggaa attttcatta ggtgttgctt
    22861 ctgttatgat tggagctgca ttctttggga caagtccggt tcttgcagat agcgtgcagt
    22921 ctggttccac ggcgaactta ccagctgatt tagctactgc tcttgcaaca gcaaaagaga
    22981 atgatgggcg tgattttgaa gcgcctaagg tgggagaaga ccaaggttct ccagaagtta
    23041 cagatggacc taagacagaa gaagaactat tagcacttga aaaagaaaaa ccggctgaag
    23101 aaaaaccaaa agaggataaa cctgcagctg ctaaacctga aacacctaag acggtaaccc
    23161 ctgaatggca aacggtagcg aataaagagc aacaaggaac agtcactatc cgagaagaaa
    23221 aaggtgtccg ctacaaccaa ctatcctcaa ctgctcaaaa tgataacgca ggcaaaccag
    23281 ccctgtttga aaagaagggc ttgaccgttg atgccaatgg aaatgcaact gttgatttaa
    23341 ccttcaaaga tgattctgaa aagggcaaat cacgctttgg tgtctttttg aaatttaaag
    23401 ataccaagaa taatgttttt gtcggttatg acaaggatgg ctggttctgg gagtataaat
    23461 ctccaacaac tagcacttgg tatagaggta gtcgtgttgc tgctcctgaa acaggatcaa
    23521 caaaccgtct ctctatcact ctcaagtcag acggtcagct aaatgccagc aataatgatg
    23581 tcaatctctt tgacacagtg actctaccag ctgcggtcaa tgaccatctt aaaaatgaga
    23641 agaagattct tctcaaggcg ggctcttatg acgatgagcg aacagttgtt agcgttaaaa
    23701 cggataacca agagggggta aaaacagagg atacccctgc tgaaaaagaa acaggtcctg
    23761 aagttgatga tagcaaggtg acttatgaca cgattcagtc taaggtcctc aaagcagtga
    23821 ttgaccaagc cttccctcgt gtcaaggaat acaccttgaa tggacatact ttgccaggac
    23881 aggtgcaaca gttcaaccaa gtctttatca ataaccaccg aatcacccct gaagtcactt
    23941 ataagaaaat caatgagaca acagcagagt acttgatgaa gattcgcgat gatgctcact
    24001 taatcaatgc ggaaatgaca gtacgcttgc aagttgtgga caatcaattg cactttgatg
    24061 tgaccaagat tgtcaaccac aatcaagtca ctccaggtca aaagattgat gacgaaagaa
    24121 aactactttc ttctattagt ttcctcggca atgctttagt ctctgtttct agtgatcaaa
    24181 ctggtgctaa gtttgatggg gcaaccatgt caaacaatac gcatgtcagc ggagatgatc
    24241 atatcgatgt aaccaatcca atgaaggatt tggctaaggg ttacatgtat ggatttgttt
    24301 ctacagataa gcttgctgct ggtgtttgga gtaactctca aaacagctat ggtggtggtt
    24361 cgaatgactg gactcgtttg acagcttata aagaaacagt cggaaatgcc aactatgtag
    24421 gaatccacag ctctgaatgg caatgggaaa aagcttataa gggcattgtt ttcccagaat
    24481 acacgaagga acttccaagt gctaaggttg ttatcactga agatgccaat gcagacaaga
    24541 acgttgattg gcaagatggt gccattgctt atcgtagcat tatgaacaat cctcaaggtt
    24601 gggaaaaagt taaggatatc acagcttacc gtatcgcgat gaactttggt tctcaagcac
    24661 aaaatccatt ccttatgacc ttggatggta tcaagaaaat caatctccat acagatggtc
    24721 ttgggcaagg tgttctcctt aaaggatatg gtagcgaagg ccatgactct ggtcacttga
    24781 actatgctga tattggtaag cgtatcggtg gtgtcgaaga cttcaagacc ctaattgaga
    24841 aggctaagaa atatggagct catctaggta tccacgttaa cgcttcagaa acttatcctg
    24901 agtctaaata cttcaatgaa aaaattctcc gtaagaatcc agatggaagc tatagctatg
    24961 gttggaactg gctagatcaa ggtatcaaca ttgatgctgc ctatgaccta gctcatggtc
    25021 gtttggcacg ttgggaagat ttgaagaaaa aacttggtga cggtctcgac tttatctatg
    25081 tggacgtttg gggtaatggt caatcaggtg ataacggtgc ctgggctacc cacgttcttg
    25141 ctaaagaaat taacaaacaa ggctggcgct ttgcgatcga gtggggccat ggtggtgagt
    25201 acgactctac cttccatcac tgggcagctg acttgaccta cggtggctac accaataaag
    25261 gtatcaacag tgccatcacc cgctttatcc gtaaccacca aaaagatgct tgggttgggg
    25321 actacagaag ttatggtggt gcagccaact atccactgct aggtggctac agcatgaaag
    25381 actttgaagg ctggcaagga agaagtgact acaatggcta tgtaaccaac ttatttgccc
    25441 atgacgtcat gactaagtac ttccaacact tcactgtaag taaatgggaa aatggtacac
    25501 cggtgactat gaccgataac ggtagcacct ataaatggac tccagaaatg cgagtggaat
    25561 tggtagatgc tgacaataat aaagtagttg taactcgtaa gtcaaatgat gtcaatagcc
    25621 cactataccg tgaacgtaca gtaacgctca acggacgtgt gatccaagat ggttcagctt
    25681 acttgactcc ttggaactgg gatgcaaatg gtaagaaact ttctactgat aaggaaaaga
    25741 tgtactactt caatacgcag gccggtgcaa caacttggac ccttccaagc gattgggcaa
    25801 agagcaaggt ttacctttac aagctaactg accaaggtaa gacagaagag caagaactaa
    25861 ctgtaaaaga tggtaaaatt accctagatc ttctagcaaa tcaaccatac gttctctatc
    25921 gttcgaaaca aaccaatcct gaaatgtcat ggagtgaagg catgcacatc tatgatcaag
    25981 gatttaatag cggtaccttg aaacactgga ccatttcagg cgatgcttct aaggcagaaa
    26041 ttgtcaagtc tcaaggggca aacgatatgc ttcgtattca aggaaacaaa gaaaaagtta
    26101 gtctcactca gaaattaact ggtttgaaac caaataccaa gtatgccgtt tatgtcggtg
    26161 tcgataaccg tagtaatgcc aaggcaagta tcactgtgaa tactggtgaa aaagaagtga
    26221 ctacttatac caataagtct ctcgccctca actatgtaaa agcttacgcc cacaatacac
    26281 gtcgtgacaa tgctacagtt gacgatacaa gttacttcca aaacatgtac gccttcttta
    26341 caactggatc ggacgtctca aatgttactc tgacattgag tcgtgaagct ggtgatcaag
    26401 caacttactt tgatgaaatt cgtacctttg aaaacaattc aagcatgtac ggagacaagc
    26461 atgatacagg taaaggcacc ttcaagcaag actttgaaaa tgttgctcag ggtatcttcc
    26521 catttgtagt gggtggtgtt gaaggtgttg aagataaccg cactcacttg tctgaaaaac
    26581 acgatccata tacacaacgt ggttggaatg gtaagaaagt cgatgatgtt atcgaaggaa
    26641 attggtcact caagacaaat ggactagtga gccgtcgtaa cttggtttac caaactattc
    26701 cgcaaaactt ccgttttgaa gcaggtaaga cctaccgtgt aacctttgaa tacgaagcag
    26761 gttcagacaa tacctatgct tttgtagtcg gtaagggaga attccagtca ggtcgtcgtg
    26821 gcactcaagc aagcaacttg gaaatgcatg aattgccaaa tacttggaca gattctaaga
    26881 aagccaagaa ggcaaccttc cttgtgacag gtgcagaaac aggggatact tgggtaggta
    26941 tctactcaac tggcaatgca agtaatactc gtggtgattc tggtggaaat gccaacttcc
    27001 gtggttataa cgacttcatg atggataatc ttcaaatcga agaaattacc ctaacaggta
    27061 agatgttgac agaaaatgct ctgaagaact acttgccaac ggttgccatg actaactaca
    27121 ccaaagagtc tatggatgct ttgaaagagg cggtctttaa cctcagtcag gccgatgatg
    27181 atatcagtgt ggaagaagcg cgtgcagaga ttgccaagat tgaatccttg aagaatgctt
    27241 tggttcagaa gaaaacggct ttggtagcag aagactttgc aagtcttaca gctcctgctc
    27301 aggctcaaga aggtcttgca aatgcctttg atggaaactt atctagttta tggcatacat
    27361 catggggcgg tggagatgta ggcaagcctg caaccatggt cttgaaagaa ccaactgaaa
    27421 tcactggact tcgttacgtt ccacgtggat cgggttcaaa tggtaacttg cgtgatgtga
    27481 aacttgttgt gacagatgag tctggcaagg agcatacctt tactgcaact gattggccag
    27541 ataacaataa gccaaaagac attgattttg gtaagacaat taaggctaag aaaattgtcc
    27601 ttacaggtac taagacttac ggagatggtg gcgataaata ccaatctgca gcggaactta
    27661 tctttactcg tccacaggta gcagaaacac ctcttgactt gtcaggctat gaagcagctt
    27721 tggctaaggc tcagaaatta acagacaaag acaatcaaga ggaagtagct agcgttcagg
    27781 caagcatgaa atatgcgacg gataaccatc tcttgacgga aagaatggtg gaatactttg
    27841 cagattatct caaccaatta aaagattctg ctacgaaacc agatgctcca actgtagaga
    27901 aacctgagtt taaacttagc tctttagctt ccgagcaagg taagacgcca gattataagc
    27961 aagaaatagc tagaccagaa acacctgaac aaatcttgcc agcaacaggt gagagtcaat
    28021 ctgacacagc cctcttccta gcaggtgtta gcctagccct atctgctctc tttgtagtaa
    28081 aaacgaagaa agactagtat ttagtaaaac ctcttaacaa gattacggaa gcagtctcta
    28141 tcttttccaa tgaggtttat agtacagaaa aagcctgaga agatgtcttc tcaggctttt
    28201 gttaagcaca taaatacaat agtgctatga caaaatcacc cagaaaaatc tgggtgataa
    28261 atgttatggt tgtgctggtt gaggattctg attttgttga tcaggggttg tatttgattg
    28321 ttgcgtatta ttgttaggat tggtagtcgt actattattt gtgcttggag tggttgagct
    28381 agactgtgaa gttgaactat ctgatgatga gcttgaactt tcagttgatg ggggttgttg
    28441 tggagcaggt gagttccacg tagaacgagc accattttta aatacgaatt ctccatttct
    28501 gtagagcccc tctggtatat tccaatcctc tggattgctt ccttcagaca gataggtcat
    28561 catagagcgg taaactttgg cagcgaccgt aaggccattg cctacaagtg gtgtcagacg
    28621 gttagaatag cctgtccata cagccattga atatttacgc gtatagccag caaatagttc
    28681 atcaggtgct acaaattgag aggtcttgat gtggttttca atttcctcgt ctgtatagtt
    28741 agaggttcct gttttaccag cctgagggag ccaagcaaga taggcatttc gtccagttcc
    28801 ataagtcaag actgttttca tcatgtcggt catcatatag gctgtcgttt ccttcatggc
    28861 acgagttccg acattagaga actctttttc actcccatca ctaaagacga ctttatggat
    28921 atacattggt ttatagtaag ttccaccatt tgcaaaggca gcgtaagcag cagccatctt
    28981 ttcactactt gctccatatt ttttgtctga ttcggttgtg ttacttgaaa tggcatttga
    29041 gtagtgaata cttgggtagt cgattcctag accatttagg aaagtcttgg cgcggttgag
    29101 tccgaccttg tttagagttt ccacggctgg gacgtttcgc gattgttgca gggcgtattg
    29161 caaggtgatg ttgccaaagt agcccctatc ccagttataa acaggagtat ttgtcccagg
    29221 gtagttatag ggctcatcgt gaacgatagt agcagttgaa tcgtagacac cgtactccaa
    29281 ggcaggagca tagtctgtga tcggtttcat agttgatccc cagtcgcggt ttgtttctac
    29341 tgcttggtta attccgaagg aaacattact tgactgatgg cgtgctccta gctgggcaat
    29401 gactttaccg ttagaaacat caacaatggt agaagcgact tgcaattcat cgtctggata
    29461 ggcaacgtat tcgtctgtat tgtaaatatc ccacagatgt ttttgagctt cttggtctac
    29521 atttgtgtag acatccatcc cagttgtgag caggttatag cctgtttctt cttcaacttg
    29581 attgatgact tccttgaggt aattatccat gtaagcaggg taattacttg ctgatttgag
    29641 actttgtagt ccatcagtaa ttggtgtatt gactgctttc tcatactgtt cagcagagat
    29701 gtagccttga tttttcattt cagataagac caagtttcgg cggtcttggg ctgcttctgg
    29761 atgtgaatag gggtcatatt ggtttggtgc ctgaggcatt ccagccagca aggctaactg
    29821 aggtaaactt aaattattga ggtctttacc atagtagttt tgagctgctg tctgcattcc
    29881 atagttccca ttagacatgt agaccttatt tatatagtag gtcaagattt cttgcttggt
    29941 tgctttttgt tctaactgaa tcgctaacca agcttcctga gccttacgag aaatagtctg
    30001 gtcggaagtc gaagttgaaa agtaagtcaa cttaatcaac tgttgagtga gagttgatcc
    30061 accttggagg gaattgcttt gcagattgcg caagaaagct cccaggatac ggatggtatc
    30121 aatccccctg tggtcgaaga agcgatggtc ttcgatagaa acgattgcct taaccaaatc
    30181 tgtgggaata tcattagctt gggcattgac gcggcgttca gaacccaagt cagcaatgag
    30241 ttgattttta ttgtcgtaga ttttactaga agttgttgca actagtttac tctcggatag
    30301 gctaggagcc ttgctaacgt agtagaaaaa aactcctccg cctaagacaa tggctgcgat
    30361 aaccaagctt aagaagctaa tgctcagata cttgattagg cgcagaatcg ttggtttgtt
    30421 catcttgttt taccacctaa taaatgttct ttgataacat tgagataagg aatttgagga
    30481 aaggcaccag ccttgatttc atatccatat tctcgaatat attcaagtgg cattgatttt
    30541 tgtcccttat cttgatgata gaagcgaatc aaatcgaatg ccggcaataa gtaggtttct
    30601 tgctgagaag aaaagtgaag aaggacaaag cagattcctt gttgggcaag gacttgttcc
    30661 atatgctgaa tctgatgtgg atgaaaattt ttcatcggaa tcgcacgttt ttgttttgtt
    30721 tccttgactt caaagtcgat gtaatatcca ttataaacgc cagaatagtc cgtcgttgaa
    30781 gcttgtcgaa aataggcttc aacaatcttg gcacgacttc gttgtggata gtccacttgt
    30841 acgatttgaa taggagttgg tttcttatgt atgacagcca agccctgaga caaatagtag
    30901 tcgttggtag cattgatcat cttttcaaaa gacattcctc gatttgcgaa atttttgggt
    30961 tgagaaagag atttttgtct tttttgtgat gaaactttat gtggatagtt gaccataatt
    31021 ctccttattg gtacaataac atcactttat tatatcataa tttgcacaga aagggttaaa
    31081 aatggctaca gctttggttt taggctattc tgcttttgat ttgggtttat tttctgataa
    31141 ggatcctcgt cttaaattga ttaaaaaagc gatacgtaaa gatttagagg ctatggcagc
    31201 agatggggtg tcttggcttg tgtttacagg aagtttgggt tttgaatatt gggttttaga
    31261 ggttgctcag gagatgaaaa ccgaatacgg tttccagttg gccaccattt ttgcttttga
    31321 aacccatggg gaaaattgga atgaaggcaa tcagatgaaa ctgagtcgct ttaagcaggt
    31381 agactttgtc aaatatgctt atcctcgcta tgaacacaag gggcagttaa gagattacca
    31441 gcagtttttg ctggaaaaca cgactagttc ctatcttttt tatgatgaag aaaatgaaat
    31501 aaaactagct tatttttacc aaaagatgaa aaatcaagag gactatttta taaagagatt
    31561 aacatttgat caattaaatg aacttgctga aaatttttcc gaaaattgaa gctttgacct
    31621 tgatttttgt ttgccttttt ttatataata atactagcaa gcgagaatgg agagagacat
    31681 ggcaagtatt attttttcag cgaaagatat ttttgaacaa gagtttggac gtgaagtccg
    31741 tggctataat aaagtagaag ttgacgagtt tttagacgat gtcatcaagg actatgaaac
    31801 ctatgctgcc ttggtcaagt cacttcgtca ggaaattgcg gatttgaagg aagaattaac
    31861 tcgtaaaccg aaaccttcac cagttcaagc agaacccctt gaagcggcaa ttacaagttc
    31921 tatgacgaat tttgatattt tgaaacgcct gaatagattg gaaaaagaag tttttggtaa
    31981 acaaatttta gataactcag atttttaagt agttatttga gatgtgcaat ttttggataa
    32041 tcgcgtgagg agaattgctt ctcatgagga aagtccatgc tagcacaggc tgtgatgcct
    32101 gtagtgtttg tgctaggcga aaccataagc ctagggacga gaaatcgtta cggcagttga
    32161 aatggctaag tccttggata ggccagagta ggcttgaaag tgccacagtg acggagtctt
    32221 tctggaaaca gagagagtgg aacgcggtaa acccctcaag ctagcaaccc aaattttggt
    32281 cggggcatgg agtacgcgga aacgaacgta gtattctgac tgctatcagc tagagctgtt
    32341 agtggtagac agatgattat cgaaggaagt ggtcctagtc acttctggaa caaaacatgg
    32401 cttatagaaa attgcatata ggttggggct gagaaatttt ctcaacctca ttttttaaag
    32461 tggacatata gaaaggtctt gcaagactgt aacatgaaaa aagaatttaa tttaattgca
    32521 actgtggcag cagggcttga ggctgtcgtt ggtcgtgaag tgcgagagtt gggctacgat
    32581 tgtcaggttg aaaatggacg tgttcgtttt caaggagacg tgagagctat tatcgaaacc
    32641 aacctttggc ttcgggcagc agatcgtatc aaaattatcg taggaacgtt cccagctaag
    32701 acttttgaag agctatttca gggagttttc gctttagatt gggaaaatta tttaccactt
    32761 ggagctcggt tcccgatttc aaaagctaaa tgtgttaagt ccaaacttca caatgagccc
    32821 agtgttcagg ctatttctaa gaaagctgtt gtcaagaaat tgcagaaaca ctatgctcgc
    32881 ccagaagggg ttcctctgat ggagaatggt ccagagttta agattgaggt ctctattctc
    32941 aaagatgtgg caactgtcat gattgatacg accgggtcta gcctctttaa acgtggttat
    33001 cgtaccgaaa aaggtggcgc tcctatcaag gaaaatatgg cagcagccat tttacaactt
    33061 tctaactggt atccagacaa gcctttgatt gatccgacct gtggttcggg gactttctgt
    33121 attgaggcag ttatgattgc tagaaagatg gcgccaggtc ttcgtcgctc ttttgcattt
    33181 gaggaatgga actggatcag cgatcgcttg attcaagaag tgcgcacaga agcggctaaa
    33241 aaagtagacc gtgagcttga gctggatatc atgggctgtg atattgatgc tcgcatggtg
    33301 gaaattgcta aggccaatgc tcaggcagct ggtgttgcag gagacattac ttttaagcag
    33361 atgcgcgtgc aggatttacg ttccgataaa atcaatggag taatcatttc caatccgcct
    33421 tatggtgaac gtttgtcaga tgatgcaggg gtgaccaagc tctatgctga gatggggcaa
    33481 gtatttgcac cgctgaaaac ttggagcaaa tttatcctga ctagtgatga agcttttgaa
    33541 agcaagtatg gtagccaagc agataagaag cgtaagttat acaacggaac cttgaaagtg
    33601 gatctgtatc aatattttgg tcagcgtgtc aaacggcaag aggtaaaata gaaagggata
    33661 ctcatgagta aaaaaagacg aaatcgtcat aaaaaagaag gtcaagaacc gcaatttgat
    33721 tttgatgaag caaaagagct aacagttggt caagctattc gtaaaaatga agaagtggaa
    33781 gcaggagtct tgcctgagga ttccattttg gacaagtatg ttaagcaaca cagagatgaa
    33841 attgaggcgg ataagtttgc gactcgtcaa tacaaaaaag aggagttagt tgaaactcag
    33901 agtctggatg atttaattca agagatgcgt gaggctgtag aggagtcaga agcttcttcg
    33961 gaggaagttc catcttctga agacatctta ctacccttgc ctctggacga tgaggagcag
    34021 ggcttggatc ctctattgtt agatgatgaa aatccaacag aaatgactga agaagtggaa
    34081 gaggagcaaa acctttctcg tctggatcaa gaggactcag aaaagaaaag taaaaaaggc
    34141 tttattttga ccgttttggc gcttgtatca gtaattattt gtgtcagtgc ttattatgtc
    34201 taccgtcaag tggctcgttc gaccaaggaa attgaaactt ctcaatcaac tacagccaat
    34261 caatcggatg tggatgattt taatacactt tatgacgcct tttacacaga tagcaataaa
    34321 acggctttga aaaatagcca gtttgataaa ctgagtcaac tcaaaacctt gcttgataaa
    34381 ctggaaggta gtcgtgaaca tacgcttgcc aaatctaaat atgatagtct agcaacgcaa
    34441 atcaaggcta ttcaagatgt caatgcacaa tttgaaaaat cagctattgt ggatggtgtg
    34501 ttggatacca atgccaaagc caaatcggat gctaaattta cggatattaa aactggaaat
    34561 acggagcttg ataaagtgct agataaggct attagccttg gtaagagcca gcaaacaagt
    34621 acttctagct caagttcaag tcaagcaagc tcaaatacga caagtgagcc aaaaccaagt
    34681 agttcaaatg agactagaag tagtcgcagt gaagtcaata tgggtctctc gagtgaaggg
    34741 gttgctgttc aaagaagtgc cagtcgtgtt gcctataatc agtctgctat tgatgatagt
    34801 aataactctg cctgggattt tgcggatggt gtcttggaac aaattctagc gacttcacgt
    34861 tcacgtggct atatcactgg agaccaatat atccttgaac gtgtcaatat cgttaacggc
    34921 aatggttatt acaacctcta taagccagat ggaacctatc tctttaccct taactgtaag
    34981 acaggctact ttgtcggaaa tggcgctggt catgcagatg acttggacta ctaagcagtc
    35041 gttacaaaat tctttctttt caaaagtaaa aatgataaaa taaaacaaat gaaacaagag
    35101 gagtgtcaaa tgacaaaagc taactttggt gtcgtaggta tggccgtaat gggtcgtaac
    35161 cttgccctta atattgaatc acgtggttac acagttgcta tctacaaccg tagtaaagaa
    35221 aaaacggaag atgtgattgc ttgccatcct gaaaagaatt ttgtaccaag ctatgacgtt
    35281 gaaagttttg taaactcaat cgaaaaacct cgtcgtatca tgctgatggt tcaagctgga
    35341 cctggtacag atgctactat ccaagccctt cttccacacc ttgacaaggg tgatatcttg
    35401 attgacggag gaaacacttt ctacaaagat accatccgtc gtaatgaaga attggcaaac
    35461 tcaggtatca actttatcgg tactggagtt tctggtggtg aaaaaggtgc ccttgaaggt
    35521 ccttctatca tgcctggtgg acaaaaagaa gcctacgaat tggttgcgga tgttcttgaa
    35581 gaaatctcag ctaaagcacc agaagatggc aaaccatgtg tgacttacat cggtcctgat
    35641 ggagctggtc actatgtgaa aatggttcac aatggtatcg agtacggtga tatgcaattg
    35701 atcgcagaaa gctatgactt gatgcaacac ttgctaggcc tttctgcaga ggatatggct
    35761 gaaatcttta ctgagtggaa caagggtgaa ttggatagct acttgattga aatcacagct
    35821 gatatcttga gccgtaaaga cgatgaaggc caagatggac caatcgtaga ctacatcctt
    35881 gatgctgcag gtaacaaggg aactggtaaa tggactagcc aatcatctct tgaccttggt
    35941 gtaccattgt cactgattac tgagtcagtg tttgcacgct acatttcaac ttacaaagaa
    36001 gaacgtgtac atgctagcaa ggtgcttcca aaaccagccg ccttcaactt tgaaggagac
    36061 aaggctgaat tgattgaaaa aatccgtcaa gccctttact tctcaaaaat catttcatac
    36121 gcacaaggat ttgctcaatt gcgtgtagcc tctaaagaaa acaactggaa cttgccattt
    36181 gcagatatcg catctatctg gcgtgatggc tgtatcatcc gttctcgttt cttgcaaaag
    36241 attacagatg cttacaaccg tgatgcagac cttgccaacc ttcttttgga tgaatacttc
    36301 ttggatgtta ctgctaagta tcaacaagca gtgcgtgata tcgtagctct tgcggttcaa
    36361 gctggtgtgc cagtgccaac tttctcagca gctattactt actttgatag ctaccgttca
    36421 gctgaccttc cagctaactt gatccaagca caacgtgact actttggtgc ccacacttac
    36481 caacgtaaag acaaagaagg aaccttccac tactcttggt atgacgaaaa ataagtaggt
    36541 cagccatggg gaaacggatt ttattacttg agaaagaacg aaatctagct cattttttaa
    36601 gtttggaact ccagaaagag cagtatcggg ttgatctggt agaggagggg caaaaagccc
    36661 tttccatggc tcttcagaca gactatgatt tgattttatt gaacgttaat ctgggagata
    36721 tgatggctca ggattttgca gaaaaattga gtcgaactaa acctgcctca gtcatcatga
    36781 ttttagatca ttgggaagac ttgcaagaag agctggaagt tgttcagcgt tttgcagttt
    36841 catacatcta taagccagtc tttatcgaaa atctggtagc gcgtatttcg gcgatcttcc
    36901 gaggtcggga cttcattgat caacactgca gtctgatgaa agttccaagg acctaccgca
    36961 atcttaggat agatgttgaa catcacacgg tttatcgtgg tgaagagatg attgctctga
    37021 cccgccgtga gtatgacctt ttggcgacac ttatgggaag caagaaagta ttgactcgtg
    37081 agcaactgtt ggaaagtgtt tggaagtatg aaagtgcgac cgagacaaat atcgtagatg
    37141 tctatatccg ctatctacgg agcaagcttg atgttaaagg tcaaaaaagc tacattaaaa
    37201 ccgtgcgtgg tgttggttac accatgcaag aatagaaaag cagttgcagt tgtgtaactg
    37261 cttttttgag gagtttttat atattgacat gcagtcgggt ctttgctaca atcgttttag
    37321 gaggatatat agatgaaact tttgaaaaaa atgatgcaag ttctactagc agtctttttc
    37381 tttggtttgc tagctacaaa tacggtattt gcgaatacca caggtggccg atttgttgat
    37441 aaggataata gaaaatatta tgtaaaagat gatcataaag caatctattg gcataaaata
    37501 gacggtaaaa cttactattt tggtgatatt ggagagatgg ttgtcggttg gcaatactta
    37561 gaaattcctg gaacaggtta tcgtgatgat ttatttgata atcgtccagt cttcgaaatt
    37621 ggccttcagg agaagtggta ctattttgga caagatggtg ctttgctaga acaaacagat
    37681 aaacaagtac tagaggcaaa aacgtctgaa aatacaggaa aagtatacgg tgaacaatat
    37741 cctctatctg ctgaaaagag aacttattat tttgataata attatgctgt aaagacaggc
    37801 tggatttatg aagacggcaa ttggtattat ttaaataagc taggaaattt tggtgatgat
    37861 tcttacaatc cactaccaat tggtgaagtt gctaagggtt ggactcaaga ttttcatgtt
    37921 actattgaca ttgatagaag caaacctgct ccatggtact acctagatcc aacaactggt
    37981 attatgcaaa caggttggca atatctaggt aataagtggt actacctccg ttcctcagga
    38041 gcaatggcca ctggctggta tcaggaaggt accacttggt attatttaga ccagccaaat
    38101 ggcgatatga aaacaggttg gcaaaacctt gggaacaaat ggtactatct ccgttcatca
    38161 ggagctatgg caactggttg gtaccaagat ggttcaactt ggtactacct aaatgcaagt
    38221 aatggagata tgaagacagg ttggttccag gtcaatggca actggtacta tgcttatagc
    38281 tcaggtgctt tggcagtgaa tacgaccgta gatggctatt ctgtcaatta taatggcgaa
    38341 tgggttcggt aatgacaggg cgcttataat tatattagaa cactcgctta atcaaagaag
    38401 tgactttgtt gtacttgacc tgacgattgg ggagattaaa agcatgtgaa atctacacat
    38461 gctttttcgt tagttatgag tgttgaactt gactaaccat tgacaaaaga taagagcaat
    38521 caaaataaga tacaaaaata tcaatgctaa ctgcaccgaa acgcccgatg ctatggacag
    38581 ggctaatagg gagagcaggg acggggcgag aatgtctact gtgctcagag cagagcccac
    38641 cgtccccatc ttgtcactgg ggatatgggc aaagacagct gcttgtaggc gagggctgag
    38701 aatgccgata atcgtagaac tgatgaaact ggtcatgaaa attacgatat aggcttgaca
    38761 aaggatacta gttattagag ccaataggga aatctcacag aaaaccaaga ggtgcgtgaa
    38821 acggatattt ttaaatagat tactgctggt catattgcca aggatagctc cacaagaaat
    38881 gatgatggag agcatggcga ggagttgccc aatgctcagt tgtgctagtg tctgttggat
    38941 gaagcggagg gcaatcagcc gaggggacac atccaagatg gcaatcatac tggtcgtcag
    39001 aaacagtagt atgacggtat cttttaacct caggagcaca gccagcgact gtttaagatg
    39061 ttgaaaatat ttcttaaaac tcagtgctgt atgtgacatt tcaatccttt tttcaacctc
    39121 atacaaggta tgtcgaataa catacaggcc caaaaaggca atgacaaaag tcagagtgtt
    39181 gataagggaa atagtttgaa tactcataac attgataagg aatgcgccag ccagattggc
    39241 gacaatgcgg acaaccctca tcagagactg cctgaacccc atggcatcat gcaggtcgtc
    39301 cttaattaca ctgatgtaga gggcgttcat catgtaggca gacaggtagc tcaaggtgtc
    39361 agagatgagg ttgatgatga caatcataat gactgaaact aatgaaaagg gcgacaagac
    39421 gagaaatact gtcaaaatag cgtagagcag gattttgatt ttggcaatcc agagtgcgtg
    39481 tttgactcta ttttcttgaa aatctcctag aatcccgaga aagagttgcg atagtagggg
    39541 aaccatctct gaaatggaaa tcagtaaaat tgctagcgga gcgaaattgt actgagccac
    39601 ataattgata atggcgaggt agaaaatact gtcgccgaat gatgaaaaac agctgtttag
    39661 cagcaactgt ctatatatgt tgtttgtcca aaataatttc atacttttct ccttatgtct
    39721 gcacatcgaa tgggaattta ttatttaata gacaccaata tacccccatg cttcctattc
    39781 cgaagtcaaa caaatctgct ttaccactat ctccttgaaa catcagtaaa ccgtgatcat
    39841 ctcgttcaga acatgctaaa attacctgtt ggattttttt catcagtaat ttgttttgat
    39901 tgtagacagt ggtttgtagt aagctagtta ttccgtggca atatcctgtc atcattttta
    39961 gatgatggtt aaaaacaaat tcttgatatt tactaataat atctttgttt ccgtcacaat
    40021 cgtacataca aagatataag attattccgg aaattccttc gcaccaagaa agttgtaaat
    40081 ttcctaaatt ttcagtatta gaagtaactt tttctaataa tttttttaat tcagtatgga
    40141 atgtatggag atcattatag aacatagaag gttctaagac tttagaatag gcaaataaag
    40201 cctatgcaat tccacaatat ccatgagcaa agctatagtc taaaatgctt tctttggcta
    40261 tatctctttg taggaaataa tgctaaattt cccctatact attgtggatg aaaattttaa
    40321 gagtattgtc attggtaaat tgatagtatt ttattaatga taataggaca ccagattttc
    40381 ccaatgcaaa gtctatttcc tctagagtat cataattctc tattaatttc ttagcggaga
    40441 cgtttgctaa ttgtagatag tattgatttt tactgataga aaataaatgt aggagtaacc
    40501 atagatagcc tgcatcacca aatagcagtg agtattgata tttatatgtg tgtgtcgttc
    40561 taattgtcac tgccttcttg atgatagaga gtattttaga atccagttct ggggggtaca
    40621 atttatttag aggaaacagt agtccagcta ttccgtgttg gaatgataaa ttacttacga
    40681 aatttccaaa ttctgttgaa gaagtgatcc ttccttcaga atttacagtt ttatctagta
    40741 aaaatcgtag aacactatta cattctgttt tgtaatcata tttatgttcc tctatttttt
    40801 taattttgac taaattattt gtttgactta aatttagtag acattgtaac caaaatagtt
    40861 gctcatctgt gagctgacct tgagtatgtg atagttctag taattgaata ggatccttta
    40921 gttagattca atcaatctat aacacaacaa cataataata cttttaggat aacttgtcaa
    40981 atattatagt aaaatgaaat aataacagga caaatcgatc aggacagtca aatcgatttc
    41041 taacaatgtt ttagaagtag aggtgtacta ttctagtttc aatctaatat agtatatatt
    41101 tttacatatt gagttgtcaa attaagtgca taagtttccc gtagcatact tcataaggcg
    41161 ttttccactt aagaaatttt cgtggtcgat tatttagaac ctgtattcac aaaaaaatgt
    41221 taaactagag ttatgacacg caaagcatat gatactgatt taaacgatca agaatgggcg
    41281 aagattgaac cctatttctg caaacaccgc acctataaat ggccgaaacg agtacttgtt
    41341 aatgaaactt tgtacgtcac taaaacaggt tgtcaatggc gcatgctccc tcatgacttt
    41401 cctctttact taatggtatg gagtttcttt catcgttcta tgacgacagg ttggttccag
    41461 gtcaatggca gatggtacta cgcttatagc tcaggtgcct tggcagtgaa tacgactgta
    41521 gatggctatt ctgtcaatta taatggtgaa tgggttcggt aatgaaagaa gcgattgtga
    41581 atggaaacaa tcgctttttt tgtgaaaata taataaaata gataggaaag aattaatact
    41641 tgtatgaaaa ataagacgtt ttttcgtcta gtaaaaggaa aaaatgacaa aaaaagttgg
    41701 tgtcggtcag gcacatagta agataatttt aataggggaa catgcggtcg tttacggtta
    41761 tcctgccatt tccctgcctc ttttggaggt ggaggtgacc tgtaaggtag ttcctgcaga
    41821 gagtccttgg cgcctttatg aggaggatac cttgtccatg gcggtttatg cctcactgga
    41881 gtatttggat atcacagaag cctgcattcg ttgtgagatt gactcggcta tccctgagaa
    41941 acgggggatg ggttcgtcag cggctatcag catagcggcc attcgtgcgg tatttgacta
    42001 ctatcaggct gatctgcctc atgatgtact agaaatcttg gtcaatcgag ctgaaatgat
    42061 tgcccatatg aatcctagtg gtttggatgc taagacctgt ctcagtgacc aacctattcg
    42121 ctttatcaag aacgtaggat ttacagaact tgagatggat ttatccgcct atttggtgat
    42181 tgccgatacg ggtgtttatg gtcatactcg tgaagccatc caagtggttc aaaataaggg
    42241 caaggatgcc ctaccgtttt tgcatgcctt gggagaatta acccagcaag cagaagttgc
    42301 gatttcacaa aaagatgctg aaggactggg acaaatcctc agtcaagcgc atttacattt
    42361 aaaagaaatt ggagtcagta gccctgaggc agactttttg gttgaaacga ctcttagcca
    42421 tggtgctctg ggtgccaaga tgagcggtgg tgggctagga ggttgtatca tagccttggt
    42481 aaccaatttg acacacgcac aagaactagc agaaagatta gaagagaaag gagctgttca
    42541 gacatggata gagagcctgt aacagtacgt tcctacgcaa atattgctat tatcaaatat
    42601 tggggaaaga aaaaagaaaa agagatggtg cctgctacta gcagtatttc tctaactttg
    42661 gaaaatatgt atacagagac gaccttgtcg cctttaccag ccaatgtaac agctgacgaa
    42721 ttttacatca atggtcagct acaaaatgag gtcgagcatg ccaagatgag taagattatt
    42781 gaccgttatc gtccagctgg tgagggcttt gtccgtatcg atactcaaaa caatatgcct
    42841 acggcagcgg gcctgtcctc aagttctagt ggtttgtccg ccctggtcaa ggcttgtaat
    42901 gcttatttca agcttggatt ggatagaagt cagttagcgc aggaagccaa gtttgcctca
    42961 ggctcttctt ctcggagttt ttatggacca ctaggagcct gggataagga tagtggagaa
    43021 atttaccctg tagagacaga cttgaaacta gctatgatta tgttggtgct agaggacaag
    43081 aaaaaaccaa tctctagccg tgacgggatg aaactttgtg tggaaacctc gacgactttc
    43141 gacgactggg ttcgtcagtc tgagaaggac tatcaggata tgctgattta tctcaaggaa
    43201 aatgattttg ccaagattgg agaattaacg gagaaaaatg ccctggctat gcatgctacg
    43261 acaaagactg ctagtccagc cttttcttat ctgacggatg cctcttatga ggctatggac
    43321 tttgttcgcc agcttcgtga gaaaggagag gcctgctact ttaccatgga tgctggtccc
    43381 aatgttaagg tcttctgtca ggagaaagac ttggagcatt tatcagaaat tttcggtcag
    43441 cgttatcgct tgattgtgtc aaaaacaaag gatttgagtc aagatgattg ctgttaaaac
    43501 ttgcggaaaa ctctattggg caggtgaata tgctatttta gagccagggc agttagcttt
    43561 gataaaggat attcccatct atatgagggc tgaaattgct ttttctgaca gctaccgtat
    43621 ctattcagat atgtttgatt tcgcagtgga cttaaggcct aatcctgact acagcttgat
    43681 tcaagaaacg attgctttga tgggagactt cctcgctgtt cgcggtcaga atttaagacc
    43741 tttttcccta aaaatctgtg gcaaaatgga acgagaaggg aaaaagtttg gtctaggttc
    43801 tagtggcagc gtcgttgtct tggttgtcaa ggctttactg gctctctata atctttcggt
    43861 tgatcagaat ctcttgttca agctgactag cgctgtcttg ctcaagcgag gagacaatgg
    43921 ttccatgggc gaccttgcct gtattgtggc agaggatttg gttctctacc agtcatttga
    43981 tcgccagaag gtggctgctt ggttagaaga agaaaacttg gcgacagttc tggagcgtga
    44041 ttggggattt tttatctcac aagtgaaacc aactttagaa tgtgatttct tagtgggatg
    44101 gaccaaggaa gtggctgtat cgagtcacat ggtccagcaa atcaagcaaa atatcaatca
    44161 aaatttttta agttcctcaa aagaaacggt ggtttctttg gtcgaagcct tggagcaggg
    44221 gaaagccgaa aaagttatcg agcaagtaga agtagccagc aagcttttag aaggcttgag
    44281 tacagatatt tacacgcctt tgcttagaca gttgaaagaa gccagtcaag atttgcaggc
    44341 cgttgccaag agtagtggtg ctggtggtgg tgactgtggc atcgccctga gttttgatgc
    44401 gcaatcaacc aaaaccttaa aaaatcgttg ggccgatctg gggattgagc tcttatatca
    44461 agaaaggata ggacatgacg acaaatcgta aggacgagca tatcctctat gcccttgagc
    44521 agaaaagttc ctgtaatagc tttgatgagg tggagctgat tcattcttcc ttgcctcttt
    44581 acaatctgga tgaaatcgat ctttcgacag agtttgctgg tcgaaagtgg gactttcctt
    44641 tttatatcaa tgccatgact ggtggaagta ataagggaag agaaatcaat caaaagctgg
    44701 ctcaggtggc ggaatcctgt ggtattttat ttgtaacggg ttcttatagc gcagccctca
    44761 aaaatccaac ggatgattct ttttctgtca agtctagtca tcccaatctc ctccttggaa
    44821 ccaatattgg attggacaag cctgtcgagt taggacttca gactgtagaa gagatgaatc
    44881 ctgttctatt gcaagtgcat gtcaatgtca tgcaggaatt actcatgccc gagggagaaa
    44941 ggaagtttag aagctggcaa tcgcatctag cagattatag caagcaaatt cccgttccta
    45001 ttgtcctcaa ggaagtgggc tttggaatgg atgccaagac aatcgaaaga gcctatgaat
    45061 tcggtgttcg tacagtggac ctatcgggtc gtggtggcac cagctttgcc tatatcgaaa
    45121 accgtcgtag tggccagcgt gattacctca atcaatgggg tcagtctacc atgcaggccc
    45181 ttctcaatgc ccaagaatgg aaagataagg tcgaactctt ggttagtgga ggggttcgga
    45241 atccgctgga tatgattaag tgcttggttt ttggtgctaa gtctgtggga ttgtcacgaa
    45301 ccgttctgga attggttgaa acctacacag ttgaagaagt gattggcatt gtccaaggct
    45361 ggaaagcaga cctacgcttg attatgtgtt cccttaactg tgccaccata gcagatctac
    45421 aaaaagtaga ctatcttctt tatggaaaat taaaagaagc aaaggatcag atgaaaaagg
    45481 cgtaaccagc gccttttttc catcctcaga ctgaggtgac ttttttgaat tgtgataaaa
    45541 tagaagggag aggatgaacc tatgagaaaa tttaaaatct ttttatttat cgaagcctgt
    45601 cttctgacag gagctctgat tttgatggta tcagagcatt tttcgcgttt tctgctgata
    45661 ctattcctct ttttgctttt gattcgctac tacactggta aagagggaaa taatcttctt
    45721 ttagtagcgg caaccattct cttctttttc atcgttatgc tcaatccttt tgtgattcta
    45781 gctatttttg ttgcggttat ctatagcctc tttcttcttt acccgatgat gaaccaggaa
    45841 aaagagcaga ccaatttggt ttttgaagag gtcgtgacgg ttaagaagga gaaaaatcgt
    45901 tggtttggaa atcttcatca tttttcaagc taccagactt gccaattcga tgatatcaat
    45961 ctctttcgct tcatgggcaa ggacactatt catctggaga gggtcatctt aaccaatcat
    46021 gacaatgtca ttatcctcag aaagatggta ggaacgacca aaatcatcgt acctgtagat
    46081 gtggaagtca gtctcagcgt taactgtctc tatggggatt tgactttttt caaccagccc
    46141 aagcgagccc tccgcaatga acactatcat caagaaacaa aagactatct caagagtaac
    46201 aagagtgtca agattttctt gaccactatg attggtgatg tggaggtggt tagaggatga
    46261 aaaaacaagc ctatgtcatt attgctctca cctccttcct atttgtcttt tttttctccc
    46321 acagcttgct ggaaatactt gattttgact ggtctatctt tttgcacgat gtcgaaaaaa
    46381 cagaaaaatt tgtcttttta ttgttggttt tcagcatgtc catgacctgt ctcttagccc
    46441 tgttttggcg agggatcgaa gagctttctc taagaaaaat gcaggctaat ctcaagcgtt
    46501 tattagcagg gcaagaagtg gttcaggttg cagatccaga tttggatgcc agtttcaagt
    46561 ccttatcagg taaacttaac cttttgacag aggctcttca aaaagctgaa aatcagagcc
    46621 ttgctcagga agaggaaatc atcgagaagg aacggaagcg aattgctcgg gatttgcacg
    46681 atacagtcag tcaggagttg tttgcggccc acatgatttt atcgggtatc agtcagcagg
    46741 ctttgaaatt ggatagagaa aagatgcaga tccagttgca gagtgtcaca gctattttag
    46801 aaactgccca gaaggatttg cgggttttgc tcttgcattt gcgaccagtt gaactggagc
    46861 agaagagctt gatagaaggg attcagattc tcttaaaaga gcttgaggac aagagtgatc
    46921 ttagggttag tctcaagcag aatatgacga aattgcctaa gaaaatcgag gagcatatct
    46981 tccgtatcct gcaagagttg attagcaata ccctccgcca tgcccaggca tcttgcctag
    47041 atgtctacct ctatcagaca gatgttgaat tgcaactgaa ggtggtggac aatgggattg
    47101 gtttccagtt agggagctta gacgacttga gttatggact gcgaaatatc aaggagcggg
    47161 ttgaagatat ggcagggacg gttcagttat taacagctcc caagcaaggg ctggcagttg
    47221 atatccgtat tcccctgtta gataaggaat gataaaggag taaagatgaa aattttacta
    47281 gtagatgacc atgaaatggt ccgtttgggt ttgaaaagct actttgacct ccaagacgat
    47341 gtagaagttg tgggtgaggc gtccaacggg tctcaaggga ttgacttggc cttggaactg
    47401 cgtccagatg tcattgtcat ggatattgtc atgcctgaga tgaatggaat tgacgcgacc
    47461 ttagcaatcc ttaaagaatg gcctgaagcc aagattttga ttgtgacctc ttatttggac
    47521 aatgaaaaaa tcatgccagt cttagatgct ggtgccaaag gctatatgct caagacttct
    47581 agtgcagatg aattgcttca tgccgtcagt aaggtagctg ctggcgagct ggccattgag
    47641 caagaggtta gcaagaaggt tgaataccac cgcaatcata tggaacttca tgaagaattg
    47701 actgcgcgtg agcgagatgt tctccaactc atcgccaagg gctacgaaaa tcagcgcatc
    47761 gcagatgacc tctttatctc tctcaagacg gtcaagaccc acgtgtccaa tattcttgcc
    47821 aaacttgaag tcagcgatcg tacccaggcg gctgtctatg cctttcagca ccatttggtg
    47881 gggcaagagg agttttagat gagtttagca gatttacttg aggagctaga agcagcaaaa
    47941 gactctaaaa aagcaaggtc catggaagcc tatatgcgcc atcaattttc ttttctaggt
    48001 attgcggtgc ctgaaagaaa taaactctat aaaaatattt tccagaagcg aaaaaaacaa
    48061 agattatcga ttgggatttt gcagacactt gctgggaaaa ggatcctaga aaataccaat
    48121 atgtggctgc taactatttg aaagcaatgc agtcttatct aaaggaaacc gatttgccta
    48181 agctagagca gttagtcgtg acaaaatcct tgtgggacac ggtagatatc ctagatcgag
    48241 tagtagggag tttggtgtat gaacaccctg aactagaaga aataatctta atactcttcg
    48301 aaaatctctt caaaccacgt cagctctatc tgcaacctca aaacagtgtt ttgagcaatc
    48361 tgcggctagc ttcctagttt gctctttgat tttcattgag tataaaatgg agcctatcag
    48421 ataatatctg gctgagacgt gtcgctattg accaccagtt gttaagaaaa gagaagacca
    48481 atactcaatt aatggaaaag attctccttc ataacttgaa ccaaacagaa ttttttatca
    48541 ataaagccat tggctggact ctgcgagact actccaaaac gaatcccact tgggtaacat
    48601 gctttattga gaaaaacaag gaaagaatgg ctgaacttag tatcaaagaa gcaagcaagt
    48661 acctctagcg tgattgaaaa gcgcagtcat taattgaaaa gtttacctgt ttatgtgata
    48721 atggagggta tttaaagaag gtggtagatt tcttgattct atagtagatt gagaaattta
    48781 gaatagtacg ctataattac attaggagga tacgataatg aagaaaactg tttataaaaa
    48841 attgggtatt tcaattattg cgagtacttt attggctagc cagttatcga cagtatctgc
    48901 tttgagtgtt atttctagta caggtgaaga atatgaggta agtgagacac tagaaaaagg
    48961 tccagagtct aatgattctt cattatctga gatttcacca acgtatggtt catactacca
    49021 aaagcaatca gaagtattat cggtaatgat gatttgatta aaattgataa tactttacag
    49081 tatccgtatt cgacttcagc tatggtttta tctaagtatt atggagtagc cgatggaatg
    49141 aatgtagaag ggaggggaag tgcgaatttt attaaagata atgtgttaat tacagcggct
    49201 cacaactact acagacatga ctatgggaaa gaagcggatg atatttatgt tcttccggct
    49261 gttagtccaa gtcaagaact atttggaaag atcaaagtaa aggaagttcg ttatttgaag
    49321 gaatttagaa atttaaattc taagaatgca agggaatatg acttggcttt attaattcta
    49381 gaagagccca ttggtgcaaa attagggact ttgggtcttc ctactagtca aaaaaatttg
    49441 acaggaataa ctgtgactat cacaggctat ctatcatata attttaaaat tcatcaaatg
    49501 tatacagata aaaaacaagt tttaagtgat gatggcatgt tcttggatta ccaagttgat
    49561 actttagagg ggtctagtgg atctgcagtt tatgatgcta gtcaccgcgt agtaggagtg
    49621 catactttag gagatggagc taatcaaatt aacagtgcag ttaaattaaa tgaacgaaat
    49681 ttgccattta tttattcggt tcttaaaggt tactctcttg aaggatggaa gaaaataaat
    49741 ggtagttggt actattatag acaacatgat aaacaaacgg gttggcagga gataaatgat
    49801 acttggtatt atttagacag ttccggtaag atgcttacag attggcaaaa agtaaatgga
    49861 aaatggtatt atctcaattc aaatagagca atggttacag gtagccaaac tatcgatggt
    49921 aaagtttata acttcgcttc atctggtgag tggatttgat gttggaggat atataaaatg
    49981 aagcttttta aaaaaatgat gcaagtcgta ctagccacat ttttcttcgg tttgctaggg
    50041 accagtacag tatttgcaga tgattctgaa ggatggcagt ttgtccaaga aaacggaaga
    50101 acctactaca aaaaggggga tctaaaagaa acctactgga gagtgataga tgggaagtac
    50161 tattattttg atcctttatc cggagagatg gttgtcggct ggcaatatat acctgctcca
    50221 cacaaggggg ttacgattgg tccttctcca agaatagaga ttgctcttag accagattgg
    50281 ttttattttg gtcaagatgg tgtattacaa gaatttgttg gcaagcaagt tttagaagca
    50341 aaaactgcta cgaataccaa caaacatcat ggggaagaat atgatagccc agcagagaaa
    50401 cgagtctatt attttgaaga tcagcgtagt tatcatactt taaaaactgg ttggatttat
    50461 gaagagggtc attggtatta tttacagaag gatggtggct ttgattcgcg catcaacaga
    50521 ttgacggtgg gagagctagc acgtggttgg gttaaggatt accctcttac ctatgatgaa
    50581 gagaagctaa aagcagctcc atggtactac ctagatccag caactggcat tatgcaaaca
    50641 ggttggcaat atctaggtaa taagtggtac tacctccatt cgtcaggagc tatggcaact
    50701 ggctggtata aggaaggctc aacttggtac tatctagatg ctgaaaatgg tgatatgaga
    50761 actggctggc aaaaccttgg gaacaaatgg tactatctcc gtttatcagg agctatggca
    50821 actggttggt atcaggaagg ttcgacttgg tactatctaa atgcaagtaa tggagatatg
    50881 aaaacaggct ggttccaagt caatggtaac tggtactatg cctatgattc aggtgcttta
    50941 gctgttaata ccacagtagg tggttactac ttaaactata atggtgaatg ggttaagtaa
    51001 tgaaggctaa ttgtaaactg tgatggatac ttaactttgt ataataggtg gataaaagtc
    51061 ttcacaatca aaaaacgcat agtatcaagg tttttctgta ctgcccccca aaagttagac
    51121 aaataattta tccaaaggat ttagttctgt actgcacagg actaagtcct tttagtttta
    51181 ccttaattct cttgttgttg taataatcaa tatagtctat aatggcttgt tccaattgat
    51241 taagtgattt aaatgttttc tcatagccat aaaacatttc cgatttcaga atcccaaaga
    51301 aggactccac catagtgctt ctctgtgaat gcctgttcca acattgtttg tacttgttct
    51361 aagttgggtg aagttgaaag attataggcg ataatttcgc tgttaaagcc atctaaaact
    51421 ggtgataagt aaagcttttg agtacttgct ggaatggaaa attcagtcac atctgtgtag
    51481 cactgttcca ttgttttaga gccttcaaat tggccttgaa tgagattctc tgccttcttg
    51541 ccaacgtctc ctttatgaga agaatatttt cgtttctgtc gcattttagc ttgtaaattg
    51601 agtactttca tcaagccttg aactctttta tgatttacca gataaccacg atttcttagt
    51661 tctaaatgaa cccggcgata agcataattt cccttgtgtt tgataaaaat ggattgaatt
    51721 tcagctttaa gctcttggtc cttatctggt ttgtctagct gtttcaagtg atagtagtag
    51781 gtcgaacgag ctagtttaat gacttttaga agaagagcta acgaaaattc agtcattaat
    51841 tcttgaacaa tttctgtctt tcttctttct ctttttcctc cttcaatcgg agttctctta
    51901 acttttttag gatagcattc tccgctctca ggtactctcc ctcttgtttt ctcaacaata
    51961 gtatacccgt ttttcctgta ttgtgctagc cagttaagaa gtatcgtacg acttgggagg
    52021 cagtattcaa gagaaactct atctttagtc cagccttcat gtcagacttt atgaatcatt
    52081 tcttgtttta aatcaggag
//
LOCUS       DAVAGB010000009        51938 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVAGB010000009 DAVAGB010000000
VERSION     DAVAGB010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51938
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.009"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(490..715)
                     /locus_tag="VQO19_000591"
                     /pseudo
     CDS             complement(490..715)
                     /locus_tag="VQO19_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            1563..2435
                     /locus_tag="VQO19_000592"
     CDS             1563..2435
                     /locus_tag="VQO19_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HET1348890.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFNSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(2581..2925)
                     /locus_tag="VQO19_000593"
                     /pseudo
     CDS             complement(2581..2925)
                     /locus_tag="VQO19_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            3068..3379
                     /locus_tag="VQO19_000594"
     CDS             3068..3379
                     /locus_tag="VQO19_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348891.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            3383..4099
                     /locus_tag="VQO19_000595"
     CDS             3383..4099
                     /locus_tag="VQO19_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET1348892.1"
                     /translation="MKKYFISGLGSNAYHSKDFFQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYSASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLALLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(4229..5044)
                     /locus_tag="VQO19_000596"
     CDS             complement(4229..5044)
                     /locus_tag="VQO19_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HET1348893.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLIIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(5041..5946)
                     /locus_tag="VQO19_000597"
     CDS             complement(5041..5946)
                     /locus_tag="VQO19_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HET1348894.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGWAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            6403..8532
                     /locus_tag="VQO19_000598"
     CDS             6403..8532
                     /locus_tag="VQO19_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HET1348895.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNVYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            8519..8968
                     /locus_tag="VQO19_000599"
     CDS             8519..8968
                     /locus_tag="VQO19_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HET1348896.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            9027..9299
                     /locus_tag="VQO19_000600"
     CDS             9027..9299
                     /locus_tag="VQO19_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET1348897.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(9653..9844)
                     /locus_tag="VQO19_000601"
     CDS             complement(9653..9844)
                     /locus_tag="VQO19_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348898.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNILSQQQK"
     gene            10272..11030
                     /locus_tag="VQO19_000602"
     CDS             10272..11030
                     /locus_tag="VQO19_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1348899.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            11032..13020
                     /locus_tag="VQO19_000603"
     CDS             11032..13020
                     /locus_tag="VQO19_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET1348900.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVFRYTYFAVANQEGTELTIFEKGQNRVQPKTIFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKTLILNDHQFSVKEEFNKDFIVKHVPNQF
                     NILTADYNYLVVPDLQAFLNQFPDSAIYNQFYGGMNVNVSEEEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSVLFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(13062..13706)
                     /locus_tag="VQO19_000604"
     CDS             complement(13062..13706)
                     /locus_tag="VQO19_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HET1348901.1"
                     /translation="MLRAGVLGANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNGECKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLGQLFSI"
     gene            complement(13678..14727)
                     /locus_tag="VQO19_000605"
                     /pseudo
     CDS             complement(13678..14727)
                     /locus_tag="VQO19_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153810.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            15434..16909
                     /locus_tag="VQO19_000606"
     CDS             15434..16909
                     /locus_tag="VQO19_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HET1348902.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(16875..17590)
                     /locus_tag="VQO19_000607"
                     /pseudo
     CDS             complement(16875..17590)
                     /locus_tag="VQO19_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            17846..18706
                     /gene="speE"
                     /locus_tag="VQO19_000608"
     CDS             17846..18706
                     /gene="speE"
                     /locus_tag="VQO19_000608"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HET1348903.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            18703..19962
                     /locus_tag="VQO19_000609"
     CDS             18703..19962
                     /locus_tag="VQO19_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HET1348904.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            19962..21089
                     /gene="nspC"
                     /locus_tag="VQO19_000610"
     CDS             19962..21089
                     /gene="nspC"
                     /locus_tag="VQO19_000610"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HET1348905.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEVGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            21086..22171
                     /gene="aguA"
                     /locus_tag="VQO19_000611"
     CDS             21086..22171
                     /gene="aguA"
                     /locus_tag="VQO19_000611"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HET1348906.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKDAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            22181..23056
                     /gene="aguB"
                     /locus_tag="VQO19_000612"
     CDS             22181..23056
                     /gene="aguB"
                     /locus_tag="VQO19_000612"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HET1348907.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(23236..24045)
                     /locus_tag="VQO19_000613"
     CDS             complement(23236..24045)
                     /locus_tag="VQO19_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET1348908.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            24317..24538
                     /locus_tag="VQO19_000614"
     CDS             24317..24538
                     /locus_tag="VQO19_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348909.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKEPNGYYPWQMEPVLTMP
                     VHGFCPRGTDDLVYIVGGNHLCKGSAARF"
     gene            24592..25263
                     /locus_tag="VQO19_000615"
     CDS             24592..25263
                     /locus_tag="VQO19_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET1348910.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRLFNYLAKPYLPASREFFQIL
                     LLLESGVLLSAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISPPS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVIMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(25315..25512)
                     /locus_tag="VQO19_000616"
     CDS             complement(25315..25512)
                     /locus_tag="VQO19_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET1348911.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            25505..26413
                     /locus_tag="VQO19_000617"
     CDS             25505..26413
                     /locus_tag="VQO19_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET1348912.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            26410..26871
                     /locus_tag="VQO19_000618"
     CDS             26410..26871
                     /locus_tag="VQO19_000618"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HET1348913.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            26861..27748
                     /locus_tag="VQO19_000619"
     CDS             26861..27748
                     /locus_tag="VQO19_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET1348914.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHSVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            27751..29646
                     /gene="cbpE"
                     /locus_tag="VQO19_000620"
                     /gene_synonym="pce"
     CDS             27751..29646
                     /gene="cbpE"
                     /locus_tag="VQO19_000620"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HET1348915.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHLDTKNSNTKNFIKNLSPEIIVQ
                     TSSSPIGSYDSGQEINREYISWLESMGIQHINAASKDYDATVFDIRQDGLINISTSYK
                     PIPSFQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNN
                     RWFYLTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQY
                     KGQWYYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWH
                     KKANDWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVS
                     IEKSATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSV
                     NKSESEQ"
     gene            29726..30856
                     /locus_tag="VQO19_000621"
     CDS             29726..30856
                     /locus_tag="VQO19_000621"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HET1348916.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDEVKVGDNDTLSA
                     QVAAMVQADLLVLLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDILRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            30866..32128
                     /locus_tag="VQO19_000622"
     CDS             30866..32128
                     /locus_tag="VQO19_000622"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HET1348917.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSHESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHEDKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            32132..32929
                     /gene="proC"
                     /locus_tag="VQO19_000623"
     CDS             32132..32929
                     /gene="proC"
                     /locus_tag="VQO19_000623"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HET1348918.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLILEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            33149..33787
                     /locus_tag="VQO19_000624"
     CDS             33149..33787
                     /locus_tag="VQO19_000624"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HET1348919.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEVKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLEKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            33784..34674
                     /locus_tag="VQO19_000625"
     CDS             33784..34674
                     /locus_tag="VQO19_000625"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HET1348920.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            34714..35031
                     /gene="yabA"
                     /locus_tag="VQO19_000626"
     CDS             34714..35031
                     /gene="yabA"
                     /locus_tag="VQO19_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HET1348921.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            35034..35912
                     /gene="rsmI"
                     /locus_tag="VQO19_000627"
     CDS             35034..35912
                     /gene="rsmI"
                     /locus_tag="VQO19_000627"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HET1348922.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     SETSLKGECLLIVEGASKGVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEENQEND"
     gene            36047..37381
                     /gene="trmFO"
                     /locus_tag="VQO19_000628"
     CDS             36047..37381
                     /gene="trmFO"
                     /locus_tag="VQO19_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HET1348923.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALTEKIHALNDGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            37465..38202
                     /locus_tag="VQO19_000629"
     CDS             37465..38202
                     /locus_tag="VQO19_000629"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HET1348924.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            38211..38768
                     /gene="frr"
                     /locus_tag="VQO19_000630"
     CDS             38211..38768
                     /gene="frr"
                     /locus_tag="VQO19_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HET1348925.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            38828..39682
                     /gene="cvfB"
                     /locus_tag="VQO19_000631"
     CDS             38828..39682
                     /gene="cvfB"
                     /locus_tag="VQO19_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HET1348926.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            39691..39906
                     /locus_tag="VQO19_000632"
     CDS             39691..39906
                     /locus_tag="VQO19_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HET1348927.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEESAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            39992..40996
                     /locus_tag="VQO19_000633"
     CDS             39992..40996
                     /locus_tag="VQO19_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HET1348928.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIYQIDFVHFSAKDVVRHPVVAQIIRAYEPAPVKKEESEELESQPLSEG
                     "
     gene            41104..41673
                     /locus_tag="VQO19_000634"
     CDS             41104..41673
                     /locus_tag="VQO19_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET1348929.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKDRIVTRVHYVLTKEDYFANK"
     gene            41741..42391
                     /locus_tag="VQO19_000635"
     CDS             41741..42391
                     /locus_tag="VQO19_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HET1348930.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            42375..44615
                     /locus_tag="VQO19_000636"
     CDS             42375..44615
                     /locus_tag="VQO19_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HET1348931.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKENVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQTTQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            44794..44982
                     /locus_tag="VQO19_000637"
     CDS             44794..44982
                     /locus_tag="VQO19_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348932.1"
                     /translation="MTATKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGGY"
     gene            45014..45601
                     /locus_tag="VQO19_000638"
     CDS             45014..45601
                     /locus_tag="VQO19_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1348933.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            45605..46786
                     /locus_tag="VQO19_000639"
     CDS             45605..46786
                     /locus_tag="VQO19_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348934.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVNLNWSMGMVLLPCLIILLLVGILFIESWGSSRKKEVFK
                     V"
     misc_feature    46946..47077
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            47093..47623
                     /gene="infC"
                     /locus_tag="VQO19_000640"
     CDS             47093..47623
                     /gene="infC"
                     /locus_tag="VQO19_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HET1348935.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            47656..47856
                     /gene="rpmI"
                     /locus_tag="VQO19_000641"
     CDS             47656..47856
                     /gene="rpmI"
                     /locus_tag="VQO19_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HET1348936.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            47908..48267
                     /gene="rplT"
                     /locus_tag="VQO19_000642"
     CDS             47908..48267
                     /gene="rplT"
                     /locus_tag="VQO19_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HET1348937.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            48325..48705
                     /locus_tag="VQO19_000643"
     CDS             48325..48705
                     /locus_tag="VQO19_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET1348938.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            48955..49755
                     /locus_tag="VQO19_000644"
     CDS             48955..49755
                     /locus_tag="VQO19_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HET1348939.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            49718..50704
                     /locus_tag="VQO19_000645"
     CDS             49718..50704
                     /locus_tag="VQO19_000645"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HET1348940.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            50746..>51938
                     /gene="lytB"
                     /locus_tag="VQO19_000646"
     CDS             50746..>51938
                     /gene="lytB"
                     /locus_tag="VQO19_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HET1348941.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWIFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWIYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDEKIAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFY
                     LKSDG"
BASE COUNT        15531 a         9568 c        11556 g        15283 t
ORIGIN      
        1 aaataagata tgcacaaatt gattagaaag tcaaatgaat ttctacaaat gttttagcaa
       61 tcgtaatgta cttgtctaga ttcgatctga tatattttcg atttaatgat atggtattta
      121 aaacctccaa agtagcttgc tccattcttt tacttacgtg agtgtagatg ttatttactg
      181 ttttagcgtt ttagcgtttt tgtgttccac tctaaccatt atagcattct tctcagctag
      241 tgtactaagg agtgtgtgcc tgaaaatatg ggaactaagg ggctggttta tcggtttctc
      301 tagtttagta tttgcctttt gcaaagtgat gttaaatgcc tttctctaaa tttacatatc
      361 actattgttt aacaaaatct aatctatttt aggtcactta ttcttttttt gaaatgtaga
      421 atgaactttt tcaaagtttt tcgaatcttt taaaatttgt ttgttttata tcgccattct
      481 cccccttttt taattctccc tatatagcct gacaactttc ccgatggtac gaatatggtt
      541 gctttcgtct aggtggatgt cggggtattt gggattgagt ttttttaagg tagccttggc
      601 ggagtttctt gacatagtta gcgccgtcta cttggaagat gccgatggta ttatagtcaa
      661 tctgtggggt attcttgata aataggtagt cgctgtttct tatctttggc tccatggact
      721 tgctgacgac ataagcgatt gggtcgtagt cgtctgggat aatggaaact ccatatctaa
      781 atcgttgtcc tgcatcgagc ggctacctgc agagataaac tacctaacac gagagtaagt
      841 agtctgtctg tagtcgtcca gtctgatgat ttttacgata cttcgttttt ctgatcatac
      901 agttgcctct cggcataggt cagaacttta ccttgtctgg gtggtgcccg ttggtcgtag
      961 atagattgga tatcgctagg agaatccttt tgaactggag aaaagagggc atcaatcaag
     1021 ctactgaata ctttaactaa gtcaaatata gtatttttct tagtagacct aacccttttt
     1081 tcataatttc taatggtgtt tttacttata cctatcttag tacccaattc ttattgagtc
     1141 caaccattac tagtctatat tgttttatag ttgattgagt ttggaatagt acgctgtagc
     1201 tgctaaaaca tttctaggaa ttaatttgcc tttcctaata gagttgttca tatcttattt
     1261 caatctacta tatttttcgc ctctaacaat cgcaatctct tctttatcta cgaatgaaat
     1321 cgctttctat ttttgtaagt aaagcatcac acgaaatcca cgaaaatgaa aacctttgtt
     1381 gtgttttcgt aaaaaatttg ttgacagagc acgaaacgcc tactataatt aaatcaagct
     1441 taaggaaata acaaaaaaac aaatcggagg gaaagacgat gaacacatta aatgagaaag
     1501 taatcaatat ctgtaaagca gtagttaaag aaactttaat ccaagacatt taggagaaag
     1561 aaatgaagaa atcaagaaaa ttagccacat taggaatctg ttcagccttg tttttaggct
     1621 tggctgcttg tcaacaacaa catgctactt ctgaggggac gaatcaaagg caaagcagtt
     1681 cagcgaaagt tccatggaaa gcttcataca ccaacctaaa caaccaggta agtacagaag
     1741 aggtcaaatc tctcttatca gctcacttgg atccaaatag tgttgatgca ttttttaatc
     1801 tcgttaatga ctataatacc attgtcggct caactggctt atcaggagat ttcacttcct
     1861 ttactcacac cgaatacgat gttgagaaaa tcagtcatct ctggaatcaa aagaagggcg
     1921 atttcgttgg gaccaactgc cgtatcaata gttattgtct tttgaaaaat tcagtcacca
     1981 ttccaaagct tgaaaagaat gaccaattgc ttttcctaga taatgatgcg attgataaag
     2041 gaaaggtctt taattcacaa gataaggaag agtttgatat tctattttcg agagttccaa
     2101 ctgaggcaac tacagatgtc aaggttcacg ctgaaaagat ggaaacattc ttctcacaat
     2161 ttcaattcaa tgaaaaagct cgaatgctgt ctgtagtctt gcacgacaat ttggatggcg
     2221 agtatctgtt tgtaggccac gttggggtct tagtacctgc tgatgacggt ttcttatttg
     2281 tagagaaatt gactttcgaa gagccctacc aagcgattaa atttgctagt aaggaagatt
     2341 gctacaagta tttgggcacc aagtatgcgg attatacagg cgagggactg gctaagcctt
     2401 ttatcatgga taatgataag tgggttaaac tttaatagtg ttatgatatg acagtaatct
     2461 taggattttt atttctattt ttgatgactt ggtgggttat ttcaatcgtt aatagccaga
     2521 aaccactcaa aaatgaaaca tttattggct atgtccaaag atacgatatt gatgggaatg
     2581 gctatcaatc attaccgtgt cctcagaact gagaggagtt cttgaaatcg taaaaccact
     2641 ttgaacaaga gttacttcaa cccattggct ctgatggatt aagttgcttt cgtgaatacc
     2701 aaaatcagcc gcaatttgtt cataagtgcg gtattctcgc acatattgaa gagtggccat
     2761 aagaaggtct tctaggctta atttaggttt tcgtccacct tttgcgtgtt taagttgata
     2821 agctgttttt aatacagcta atatctcttc aaaagtcgtg cgctgaacac caacaagaca
     2881 tttaaatcgt gcatcagtta gttgtttact tgcttcataa ttcatagaac tactatacca
     2941 tattttgttt cgcaggaagt ctaatgctaa aatcttatca gtgagaagat ttcttaaagt
     3001 ttattctttg tagtttcatc tgtattagta cataatttaa cttagagaaa ataggaggac
     3061 taatcgaatg gaattaaaag attttacaga aaaagaacag gaaatgatta agaaaaggct
     3121 tacaatgtct aatattagtg acaaagaaac tactgagaag attctggcgc tagtaccaca
     3181 agacttgatt aagcgaatcc cgttttttgt cagaaaacat gctacaacac gtacgattaa
     3241 acgcatttca attgaacacc ctgaactcta cgctgtagct caaacaagtg gtgagattcc
     3301 ggaaaaagaa cgcgaagaat tgcgtcagat tatcacgact atctttgaac aaaagatgaa
     3361 taagcatagt attaagtaga gaatgaaaaa atattttatt agcggtttgg gaagcaatgc
     3421 ctatcatagc aaggattttt ttcaagaact agattcgcag gtctattttc taaatccata
     3481 tgaaaagcat cttcgagatg aaacagaatt gaaatcatgg tttaaaaatg agattgtaga
     3541 ggaagaatct atctgtctga taggtcattc tcttggagga gatttagctc gttattccgc
     3601 atcggaattt gaagaagtaa agaaactgat tcttttggat ggtggctatc tagatttaga
     3661 taagatttta cctttggata cagagttaga ggaaactaaa aattatatca aatctcaaat
     3721 tgtttcggac ttagctcttc ttacttctaa agaaaaatct gaagcaaagc attggtcaga
     3781 aaatatggag aaagctgtaa gacagtccta tcactggaat gttgagtata atagatatga
     3841 gttggctata aattatgaaa atatagaagc gatactccgc ctacggagaa aaatacaagc
     3901 ttttaagaga gaagtgggag ataccttgtt tattagtcct cgctatccta atgaagctac
     3961 atggagagag gaagccctaa aagaattgcc agactatttt gatactattt ttttagaaaa
     4021 ctttggccat gagctttata ctcaagcacc taaagaaatc gctagtctaa tgaatgagtg
     4081 gctcgcttat tttctatgag ctacttgtat tgctggaaat ggtataagat gaaaatctac
     4141 aagtcactaa ttttcatata accaaaaaac gaacaggctc tttttctgtt attcagaaga
     4201 gaacttgttc gtttttatct tgattttctt aaaaagctct atatacatag ggattttctg
     4261 gtttatcgac tttggtaaag ctgtcgattt ccaaggttgg aaggttttgt ttgagttctt
     4321 tatggtagtg attgaccagt tttcctttgg ctgaaatcca agtgttgttt tcatactgcc
     4381 gggtattgcc cttggtcagc aatccataga caccagaatc tgcgatacag tggataatac
     4441 cgaatcggaa cagaaattga ctattggcat gactggggtc gttatagaca aagcctgtaa
     4501 actggattgt cttgccctca aactcatctg gatagtcgta gatagcctcc atgacttcca
     4561 tatagttttc attagtgatc tgaatactat cttgggataa gtatttatcc gccgccgttc
     4621 gcatttcctt ttcataggct gattttgaaa aataagaact ggtatctggt ttcaaatatt
     4681 ggcttgtcgt cccttcgctt gtctgaatgg ctagatccgt tccttctgat agggggaaat
     4741 gataaccttt agcagaaacg gtctgagaat ccaagctaac agttgggaaa gttaagccga
     4801 tgataagtgg aatagccaga agagaaatac tcgtcatctt ggccaatcgg ctgttcagat
     4861 gactgtgggt tttgacttgc ttcatccaga tatacaattg aacaattgcc aagataaagg
     4921 aaagcaccat ggagatatag gccagatagg aatagtgcat gttgatgtac tggtttagtt
     4981 tgcccgacag atggaggtaa atagtcagtt caaaatagcc agctaaaact aaaaatcgaa
     5041 tcataggatg actccaatca agagagaata ggctaaaacg accagagtca caatcgtaat
     5101 gaagtgacta ataaatcgtg ctttcaagta atttttcatc atgagaatat ttttgatatc
     5161 cagcattggg ccaatgacga gaaaggccag aactggtgcc caaccgaaac tcgagagtag
     5221 agaagcacct ataaaggcat ccgcctcact acagagcgaa agaagaaagg ccaaaagcat
     5281 caagagcagg atggcaaaaa gaggagtcgc actgatagag gtcagaatcc gagtcggaac
     5341 gtagacctgt attatagaag caaagaggca gccaaatacc aaataacgcc ccgtatcaaa
     5401 aaattcatca atggcctgca caaagacttg aaaaactttt tttgcagaac tcaagtaaga
     5461 aaaatcatgc tcatgacaag ccagacgatt ttctttctga atcggttctt gccagaaaaa
     5521 tcctagaaaa attcctagta ttacagccac aagaatggaa cccagagctc gtaatagggc
     5581 gacatggaag gagttgccaa aggcagaata ggtcgcaaaa agaacaatgg gattgataac
     5641 aggtgctgtc acaagaaaag gaacggccgt gtaacttgga accttttttt ccagaaaacg
     5701 attgatgatg gggacgattc cacattcaca agaagggaaa agtataccga caaaggtccc
     5761 aaaaaagatt ctcccccaac gatttcgagg gagaaaatga taaaccttgt caggtgtgat
     5821 ataaacttca atcagccctg agacaatgct tcctatcaga acgaagggaa gggcttcaat
     5881 gataatggag agaaaaatgg ctccagtttg aagtacacta gatgggagtt gttgaaaagc
     5941 agtcatctag tttttctttt ctgctttgac ttttttctct ttgtcatcag ggaaagtaac
     6001 ttgtttcaaa tcagggagtt tagcaaactc ttcaaacatc ttgtccaagt cgtctcgttt
     6061 tgtaaatttg acagccatag gtgtacctcg attctaaatt ctacctctat tatactatta
     6121 ttttgcggaa aagggagttt tttaatttgt tttcgatagt tgatacactt cgaaaatctc
     6181 ttcaaaccac gtcagcttcg ccttaccgta gtacggttac tgacttcgtc agttctatcc
     6241 acaacctcaa aacagtgttt tgagctgact tcgtcagtct tatccacaac ctcaaaacag
     6301 tattttgagc agcctgcggc tagcttccta gtttgctttt tgattttcat tgagtatgaa
     6361 aaggattgga gaaagccttc cagcttgtgg tataatagat ttatggataa aaaatatgaa
     6421 aaaatctctc aggatttggg agtgacgtta aagcaaattg ataccgttct aagtttgaca
     6481 gctgaagggg cgactattcc ctttatcgcg cgttatcgca aggacatgac tggtagtctg
     6541 gatgaggtgg cgattaaggc tattattgat ttggataaaa gtctgacaaa tctcaatgac
     6601 cgtaaggaag ctgtcttagc taagattcaa gaacaaggta agttgaccaa ggaattggaa
     6661 gaagctatct tagttgccga aaaattagca gacgttgaag aactctatct tccttataag
     6721 gaaaagcgtc gtaccaaggc aaccattgcc cgtgaagctg gactctttcc tcttgctcgc
     6781 ttgattttgc agaatatagt tgacttagag aaagaagctg aaaagttcgt ctgtgaagga
     6841 tttgcgactg gcaaggaagc cttgaccggt gcagttgata ttttggtcga agccttatcg
     6901 gaagatgtga ccttgcgttc tatgacttat caggaagtgc tgagacactc taaacttact
     6961 tctcaagcca aggatgaaag tcttgatgaa aagcaggttt ttcagattta ttatgatttt
     7021 tcagagacag ttggaactat gcaaggctat cgtaccttgg ctctcaatcg tggggagaaa
     7081 cttggtgtct tgaagatcgg ttttgaacat gcgacggacc gtattcttgc cttctttgct
     7141 actcgtttca aggtgaaaaa tgtttatatt gatgaagttg ttcagcaatc cgttaagaaa
     7201 aaggtcttgc ctgctatcga gcgtcgtatt cggacagaat taactgagaa agctgaagaa
     7261 ggagctatcc aacttttttc tgacaatctg cgcaatctcc tcttggttgc tccactgaaa
     7321 gggcgcgtgg ttcttggatt tgacccagcc tttcgtacag gtgccaagtt agctgtcgtg
     7381 gatgcaacag gaaaaatgct gacaactcag gttatttatc ctgttaaacc agcatcagct
     7441 cgtcaaatcg aagaagccaa gaaagattta gcagatttaa ttggtcaata cggtgtagag
     7501 attattgcca ttggaaatgg aacggccagt cgtgaaagtg aagcttttgt agcggaagtt
     7561 ctgaaagatt tccctgaagt cagctatgtt atcgttaatg aaagtggtgc ttctgtctat
     7621 tctgccagcg aacttgctcg tcaggagttt ccagacttga ccgttgaaaa acgttctgcc
     7681 atttctatcg cccgtcgttt gcaagatcct cttgcggaat tggtcaaaat cgatcctaag
     7741 tcaattggtg tcggtcaata ccaacacgat gtcagtcaga agaaactatc tgagagtctg
     7801 gactttgttg tcgatacagt ggttaaccaa gttggtgtca atgtcaatac agctagccca
     7861 gctcttcttt cacacgtagc tggactcaac aaaactatct ctgaaaatat tgtcaaatac
     7921 cgcgaggaag aaggaaaaat cacttcacgc gcccaaatca agaaagttcc tcgtctggga
     7981 gccaaggcct ttgagcaggc tgctggtttc cttcgtatcc ctgaaagtag caatatcctt
     8041 gataatacag gagttcaccc agagaattac actgcagtta aggaactctt caaacgttta
     8101 gatattaaag acctaaacga agaagcccaa agcaaactca agtccctttc agtcaaggaa
     8161 atggctcaag agctagacct cggtccagaa acccttaaag atatcattgc agatcttctc
     8221 aaaccaggtc gagatttccg tgattccttt gacgcacctg tgcttcgcca agatgtccta
     8281 gatatcaaag acctagtggt aggtcagaag ctagaaggtg ttgtgcgtaa cgttgttgac
     8341 ttcggtgcct tcgttgatat cgggattcac gaggacggct tgattcatat ttctcatatg
     8401 agtcgcaagt ttatcaaaca ccctagtcaa gtggtgtcag ttggagattt ggtgaccgtt
     8461 tgggtcaaga aaattgatac tgaacgtgaa aaagttaatc tgtcgctcct cgctccaaat
     8521 gaaactgact gattatgtca agcaggtttc actagaagac ttcgggagag cttttatcca
     8581 tcatgtccag tggaataggc gtctacgttc gacaggtggg cgatttttcc ccaaagatgg
     8641 gcatctggat tttaatccca aggtttatca gaaactgggt atggaggttt ttaggaaaat
     8701 tgtccgacat gaactctgtc attatcacct ttatttccaa gggaagggct atcaacacaa
     8761 ggatcgggat tttaaggaac ttttgaaagc agtggatgga ttacggtttg taccatcctt
     8821 gcccaatagt aactctaaac cactcaagct ttatcgttgt caatcctgcc agcaaaggta
     8881 tcagcgcaag cgtaggattg ataccaaacg ctatcgctgt ggactttgtc gaggtaaatt
     8941 gcttctgata aatcagcctg aggactgatg aaagccgagc ctccccgtga tatactatgt
     9001 ctaacctagc agaaagagga aatatcatga acagtaaatt ttataaaatg agacgcaatc
     9061 gcatgatttc aggagttctg gcaggtctgt cagacaagtg gaattttgat gttaccctag
     9121 ttcgtttctt gtttgctatt tttacagttg caaactttgg acttggcgtg attatctata
     9181 tcatcctagc ttctatcatg cctaccaagg aagaaatcga agcagaaatg tacggaacag
     9241 gcccacgtaa acgcaaagaa gcccaagcca ttgacgacaa tgaaggctgg ttttggtgag
     9301 gttctacaga agatttggaa taagcaaaaa gctttaaatc aatagtctaa actgcttgat
     9361 ttaaagcttt tttactttta tactcaataa aaatcaaagt gcaaactagg aagccagcca
     9421 caggctgtaa tttagtcggc aatgtgaagt tgacatagtt tgcactttga tttttgaata
     9481 gtattaataa tatttcgcca gcttcatcca caaactatag tggattggaa ctagaatagt
     9541 acacctctac ttctaaaaca ttgttagaaa tcgatttgac tatcctgatc gatttgtcct
     9601 gttcttattt cattttatta taaaagcagt aatttaaacg cagtttttta atctattttt
     9661 gctgctgaga caatatattt ttggaaaaat ggtggatgct gataacaact gataaccagc
     9721 aaataacata agcagtgccg gtaaattctg taccgataaa gtgtgtgtgt tcaactaaga
     9781 gctgaccgat gaatggagag agcagataga gaagtccgat gagtatatgt tctttgtgtt
     9841 tcattaaagc gcaccttctt tccttatagg ttgaacgact tgcaagtgtt aaattgaatg
     9901 gtatgttatc taggtaacct tactaaaatg ttagttcccg cttcctcctt ttcaaagtaa
     9961 gccttttcac acttatattt tacaacttta aaaataggaa atcaaatcat tttctaagta
    10021 attttgctta tatttcaccc aatcttacaa aaatgtaaga ttaaagtctc ttttgtaagg
    10081 ttaggttatg gcaagcggtc tttttttgat gtaaactaga ctcataaaga acaaaggagt
    10141 aacatcatga aacaaatctt acataagaaa actagaaaac caagtcacaa agaaattgag
    10201 cgcgttcagc tgggatgcac tatgatgcaa gctacatttc atttgatggg atattaagaa
    10261 aggagattct catgacactt ttagatgtaa aacacgttca aaaaatttat aaaacacgtt
    10321 ttcagggcaa ccaagtagaa gccctcaagg atattcactt taccgtcgaa aagggtgact
    10381 acgttgccat catgggtgag tctggttctg gtaaatcaac tcttctcaat attctagcta
    10441 tgctggataa accaagtcgt ggtcaggttt acttgaatgg aactgacacc gcaaccatta
    10501 aaaattcaca ggcctctagc ttccgtcgtg aaaagttggg ctttgtcttc caagacttta
    10561 acttgctaga tactctatct gtaaaggaca atatcttgct tccgcttgtc ttgtcaagaa
    10621 gacctattac agagatgatg aagaaattgg tggtgacagc tgagaatctg ggaataaacc
    10681 aattacaaga gaagtaccct tacgagattt ctggtggtca gaaacagcgt gtagcagtag
    10741 cccgcgccat catcacagaa cctgaaattc tccttgcgga cgaaccgaca ggagctcttg
    10801 actccaagtc atctgcagcc ttacttgatg tctttgatga aatcaatgag cgcggccaaa
    10861 ccattctcat ggtaacccac tcaacagcag cagctagcag agctaaacgt gtactcttta
    10921 tcaaagacgg cattctttac aatcaaatct accgtggaga gaagacagaa cgtcagatgt
    10981 tccaagaaat ctctgatacc ttgactgtca tggcaagcga ggtgaattag tatgtttcga
    11041 ttaaccaata agttagcggt atcgaacttg attaaaaacc gcaaactcta ctatcctttt
    11101 gcgctggctg ttctcttggc agtcactgtc acctatctct tttactctct aaccttcaat
    11161 cctaagattg cggaaatccg tggaggaaca accattcagg ctacacttgg atttggtatg
    11221 tttgtcgtca cccttgcgtc agccattatc gttctctatg ccaatagttt tgtcatgaag
    11281 aaccgttcca aggaactagg aatttatggc atgttgggct tggagaagcg tcatcttatc
    11341 agtatgacct ttaaggagtt agtggtattt gggattctaa ctgttggagc gggtatcggt
    11401 attggagcct tgtttgacaa gttaattttc gctttcctgc tcaaactaat gaaattgaag
    11461 gttgagctgg ttgctacctt ccagacgaaa gttgtcatta cagtgcttgt tgtcttcggt
    11521 ttgattttcc taggcctcat gttcctgaat gcccttcgaa tcgcccgtat gaatgccctc
    11581 cagctctctc gtgagaaagc tagtggagag aaaaaaggtc gcttccttcc tctccaaacc
    11641 attcttggtt ccataagttt aggaattggc tattatcttg cccttacggt aaaagatcct
    11701 cttacagcct taacaacctt cttcatagct gttttactgg ttatctttgg gacttatctc
    11761 ttgtttaatg cagggattac cgttttcctc caaatcttaa agaaaaataa gaaatactat
    11821 taccaaccaa ataacctcat atctgtttct aacttgattt tccgtatgaa gaaaaatgca
    11881 gttggactag ccaccatcgc tatcttgtca acaatggttt tggtaaccat gtcagcagcg
    11941 acaagcattt tcaattcctc agaaagcttt aaaaaagttc taaatcctca tgattttggg
    12001 gtttcagggc aaaatgttga aaaagaagac ttggacaaac tcttgagcca gtttgcaagt
    12061 gacaaaggtt ataagattaa agaaaaagaa gtatttcgtt acacttactt tgctgttgcg
    12121 aatcaagaag gaaccgagtt aactattttt gaaaaaggac aaaaccgtgt ccaaccaaaa
    12181 acaattttca tggtatttga ccaaaaagat tatgaaaata tgactggtca aaaactgtct
    12241 ctatcaggaa atgaggtcgg actctttgca aagaatgagg gagttaaaga acagaaaact
    12301 ctaattctga atgatcatca attttctgta aaagaagaat ttaataaaga ttttattgtc
    12361 aagcatgtcc caaatcagtt taatattttg actgctgatt acaattacct tgttgtacct
    12421 gatttacaag cctttttgaa ccaattccca gattcggcta tctataatca gttttacggt
    12481 ggtatgaatg taaatgtcag tgaagaagag caactcaaag tcgctgaaga atatgaaaaa
    12541 tacttacaaa agtttaatgc tcaattaaac actgaaggta actatgtgta tggtagcact
    12601 ctagcagatg ctagtgctca aatgagtgtc ctctttggcg gtgtcttctt tatcggtatt
    12661 ttcctatcca ttatctttat ggtcggaacc gttctggtca tctactacaa acaaatttct
    12721 gaaggctacg aagaccgtga gcgctttatt atcttgcaga aagtcggttt agatcaaaag
    12781 caaatcaagc aaaccatcaa caaacaggtt ttaactgtat tcttccttcc tttgctcttt
    12841 gccttcctac atctagcctt tgcctaccat atgcttagtc tgattttaaa agtgattggt
    12901 gtactggata cgactatgat gttgattgtg accttgtcta tctgcgctat cttcctcatc
    12961 gcctatgtgc tgattttcat gattacttca agaagttatc gcaagattgt gcaaatgtaa
    13021 aaaagatacc tcgacttcaa aatcgaggta tttcttgttt tctaaatgct gaaaagttgt
    13081 ccgagcagga aggtaactcc catagttaag agaccaatag caaggttccg aatcatagct
    13141 gttttggttg gggcttttcc aagtctagcg cttgtgtagc cagtgagaag aagggctaca
    13201 ccgacgataa ggacggtagc agggatgcgg taatcacttg gaaaaatggt cactgacagc
    13261 attggaggca aacttctaag gaaaaaggca acgaagctag aaatggcagc gtgccaagga
    13321 ttggtaaatt cttcatactc aatcccatat ttttcctcta ccagagcctt gagtggattt
    13381 ttaagaaaga tcttattggt caagagttgg gcagaagttt tgcattctcc attttggata
    13441 taagcagcat agagggattt tttggctagt tccctatctt ggtctaacaa gagtttttct
    13501 cgcgaaacgg cagcttcctc ggtatctttt ggagttgaaa cggatacata ttctccacca
    13561 gccattgaaa aggcaccagc taagatagcc gcaaatcctg ataaaaagat aatccagata
    13621 ttggtcgtgg cactggcaac cccgataacc acaccagcaa tggaaataat tccatcgtta
    13681 gcaccaagaa cacctgcgcg caggatattt aaacgacctg caaaatttga atcgatttcg
    13741 tgatttgttt ctgacgctaa atttcaagtt caagttagcc atccagaagt cttctctggg
    13801 tgacttgtag tccaagcatt ttttaggata gttgttaatc cacttttcga tgaatgcgac
    13861 ttccttagga gtcattttct tggttccctt aggtaaccat ctacgaatga acctgttgtg
    13921 attctcatta gttccccttt cccaagaggc ataggggtgc gcataataaa tgtgctcctc
    13981 agaaaataca tcagacaagc gattgaattc cgttccatta tctgccgtga tggaaagaat
    14041 cttgtgttgt tttaagatga gttttagagc ctgattgacc acctcagcac ttttatttgg
    14101 aatcaatcgg atgatctgat gtctactctt tcgatccgtc aagacaagca agcagtagtt
    14161 tttcgatctc gtaagtagaa ccgtatcaat ctcataatgc ccattctcca agcgaagatt
    14221 gatagcttca ggccgctgtg cgatggattg accagcaggt ttaaagttgg tgctagcctg
    14281 tttcttaagc acttttcctt ttctagggta aagcagatcc tgcttgctta accccaattt
    14341 tccatgatga atccaatagt aaatggttga aattcccacg ttaacccctt tagccatcac
    14401 catcatttca ggcgaaaatt tttggttatg atagtggaga atcttttcct ttagttcctt
    14461 tgtcaagctt gatttcttga ccgagcgctt gcgattgttt tcataagact gttgagcata
    14521 gtcggcagaa taaacctctt tgaagcgccc ttttccaaga cattgtcgga ctgtcccacg
    14581 cttgatttca gtgtggatag tttaaggagc ttttccaagt agagaggcaa tttctctatt
    14641 tgatttccct tcttttttcc atctttcgat taagcgacgg ctatcgattg tcaaatgttt
    14701 ggcttttgta gtataatttt cttgcatctc tgtgcctttc ttgtgtttgt ggttgaacaa
    14761 caagtataac acagaggtgt tttcttatgc ctacaagagc tatcagctag ttgaaccatc
    14821 taatttttag gagggctggg tggctaactt cattatagaa ctttcattta cgaacatata
    14881 gtaaaatgaa acaagaacag aacaaatcga tcaggacagt aaaatctatt tctaataatg
    14941 ttttagaagc agaagtgtac tattctagtt tcaatctatt atatttttgt tttttatcaa
    15001 aaaatacttt acaagttctt aaaaacatga tatagtaata aagcttagaa aatgagatga
    15061 tgttttctag caaatataaa cccgagtaaa aaatgcctac ggacaggcag ggttgaatgc
    15121 cgaagcgtgg ttgaaaagcc acattattga tagggttaaa agcctacttt tataagttga
    15181 tgttaggaca cttgtcctaa ttcataaatt tttagtgtgg tgaaagcaca cgtcatcttg
    15241 tgaaacgatc aataaagtac gtaatatttg ctactagaga gttaggaaac atcgggaaca
    15301 gacatactca acagaaacca aaataaacac gtcagaagat tgcagagcag gtgaaaacct
    15361 gctctttttt catgagtcaa cctttagttc cttagttttc ataaggtcct aaaaatattg
    15421 aaaggagtat gttttgaaag agttagatca aaaccaagcc ccaatttatg aggccttggt
    15481 gaagttacgc aagaaaagga ttgttccctt tgatgttcca ggtcacaagc gtggacgggg
    15541 aaatccagaa cttgtcgaac tcttaggaga aaaatgtgta ggcattgatg tcaattcgat
    15601 gaaacccttg gataatttag gccatcctat ttcgattatt cgtgatgcag aggagctggc
    15661 tgcagatgct tttggagcta gccatgcctt tctaatgatt ggtggaacaa cttcatcggt
    15721 gcagactatg attctggcaa cctgcaaggc aggagataag attattctgc cacgaaatgt
    15781 ccataaatct gctatcaatg cgttggttct atgtggtgcc attcccatct atatcgagat
    15841 gagtgtagat cctaagattg gtatcgcttt aggtcttgaa aatgaccgag tagcacaggc
    15901 cataaaggac catccagatg ctaaggctat cctaatcaac aatcctactt actacggcat
    15961 ctgttcagac ctaaaggggt tgacagaaat ggctcatgaa gctggcatga tggttttagt
    16021 agatgaagcc catggagcgc atttgcattt cactggtaaa cttccaattt ctgctatgga
    16081 tgcaggagct gatatggcag cagtttccat gcataagtct ggtgggagtt tgacacaaag
    16141 ttcgcttctt ttaatcgggg agcagatgaa tcccgaatac gttcgtcaga ttataaacct
    16201 gacccagtct acatctgcct cttacttatt gatggctagt ttggatattt cacgtcgcaa
    16261 cttggccctt cgtggtaaag agtcgtttga ggaagtcatt gagctatccg agtacgctcg
    16321 tcatgaaatc aatgccattg gcggttacta tgcttactca aaagagttaa tagatggtgt
    16381 gtcggtctgt gattttgatg taaccaagtt gtcagtttac actcagggaa taggcttaac
    16441 aggtatcgag gtttatgacc tcttgcgaga cgaatacgac attcagatcg agtttggtga
    16501 tatcggcaat atcttggcct atatttccat cggcgaccgc atccaagaca tcgagcgctt
    16561 ggttggtgct ctggctgata ttaagagact ctattcacga gatgggaagg acttaatagc
    16621 tggagaatat attcagcccg agttggtgct gtctccacaa gaagccttct attcagagag
    16681 aaaaagtttg accttagatg agtctgttgg acaggtctgt ggagaatttg tcatgtgcta
    16741 tcctccaggg attcctatct tggctcctgg tgaacgcatt acacgagaaa ttgtagacta
    16801 tatccaattc gccaaggaac gtggttgctc cctccaaggg acggaagatc cagaggtcaa
    16861 tcatatcaac gttattaaga gaaagacaaa ctataagaaa agtcaatagt tttatctaaa
    16921 ctatttctta tttcaatttg atgatttggc gatgatttta gagcacggca aaaagccctt
    16981 gaattagaag cggtcaatcg cttaatttct atcagcttat caaatcctgc ctcaatcctt
    17041 ttctgaggat tagggtagcg tgtcaagagt tggtaggtat attctgaatg ctttccaacg
    17101 attttatcca actcaggaaa gatgatatca agacaacgag tgtattgtac tttccaatca
    17161 gactgttttt cttgagacga tgaatatgtc tagccagtat ttttagttct acttgccgat
    17221 tatcgtgttg aaattgttca cgattggggt cagaaagaag tttaagagcg atgccatgag
    17281 cgtctttctt atccgtttta gtcttgcgaa gtgataatga tttggcaaat tccttgatga
    17341 gcaaaggatt gcaggtgtaa actttatatc cttgttcatg caggaagttc agtagattaa
    17401 aggcataatg tccggtattt tcaagagcga tgagacagtc ttggttgagt tgtcgaagag
    17461 acagatctaa gagttcaaaa ccagctttat tatttgaaaa agtgagtggt ttaagaacag
    17521 tttttcctgg aacattcaag gctgtaacat cgtgtttatt tttagcgaca tcaatgccca
    17581 cataaagcat gggagtacct ccagatgtag tatttcaagt ctacttggtt atccacgaat
    17641 tttttgcctt gttaccttag acgagataaa acgtctatgc gttatcaaac tcattaccaa
    17701 ttgaaacaaa aaactgtggt tagagccttt cggaaatcgt caagcgattg gagggaataa
    17761 actaatccac agtggcttat tccaagtata ccacttgggc tttggcagta gctaactgcg
    17821 ctaaatataa tataaggaga aatagatgga tttatggttt tctgaagttc atactccaga
    17881 tgtcaaattg tctctgagaa cagccaagca actttacgct ggaaaaagtg aatggcagga
    17941 tatcgaagtc ttggatacgc cagcttttgg gaaaatactg attttaaatg gccatgtctt
    18001 gttctcagat gcggatgatt tcgtctacaa tgaaatgacc gttcacgttc ccatggctgt
    18061 ccacccaaat ccaaagaaag tattggttat tgggggtggt gacggcggtg ttgcccaagt
    18121 attaacactc tatcctgaac tggaacaaat cgatatcgtg gaaccggatg agatgttggt
    18181 cgaggtctgt cgtgagtatt tcccagactt tgctgcaggg ctagatgatc ctcgtgttac
    18241 catttactac caaaatgggc tacgcttttt gcgaaactgc gaagatgatt acgatattat
    18301 catcaacgat gcgacagatc catttggcca tacggaagga ctctttacca aggaattcta
    18361 cggcaatagt tatcgagctc tgaaggaaga cggcatcatg atttaccagc atgggagtcc
    18421 cttctttgac gaggatgagt cggcctgccg aagcatgcac cgcaaggtca atcaatcctt
    18481 tccaatcagt cgggtttatc aggcccatat tccaactagc ccagctggct attggttgtt
    18541 tggatttgca tcgaaaaaat accaccctgt caaagatttt gacaaggaag gttggaaaaa
    18601 acgccagctt ttcacagaat actacactgc aaacttacac gtgggatcct ttatgttgcc
    18661 caagtatgtt gaggacattt tagaagaaga ggaaggaaaa aaatgagtcg tttactagtt
    18721 attggttgtg ggggcgttgc ccaagttgct atttcaaaga tttgtcaaga tagcgaaaca
    18781 tttacagaga ttatgattgc tagccgtacc aagtcaaaat gcgatgactt gaaagcgaag
    18841 ctagaaggca aaacaagtac taaaattgaa actgcagcac ttgatgctga caaggttgaa
    18901 gaagtgattg ccctgattga aagctacaaa ccagaagctg ttttgaatgt agctctgcct
    18961 tatcaagatt taaccattat ggatgcttgt ttggcaacag gtgttcacta tatcgataca
    19021 gccaactacg aagcagaaga cacagaagac cctgagtggc gtgctatcta cgaaaaacgt
    19081 tgtaaggaac ttggttttac agcctacttt gactactcat ggcagtgggc ttatcaagag
    19141 aaattcaaag aagcaggctt gactgctctt cttggttctg gctttgaccc aggtgtaact
    19201 agtgtctttt cagcttatgc cctcaaacac tattttgatg aaatccatta tatcgacatt
    19261 ttagactgta atggcggtga ccacggttat ccatttgcaa ccaactttaa tccagaaatt
    19321 aatctccgtg aggtttctgc gccaggttct tactgggaag atgggaaatg ggtcgaagtc
    19381 gaagctatgt ctatcaagcg tgagtatgat ttccctcaag ttggacaaaa agatatgtat
    19441 ctccttcacc atgaagaaat cgaatcattg gccaagaaca ttccaggtgt caaacgcatt
    19501 cgtttcttta tgacttttgg tcaatcttac ttgacgcaca tgaaatgtct tgaaaatgtt
    19561 ggactccttc gtacggatac cattaacttt aacggccaag aaattgttcc aattcaattt
    19621 ttgaaagcct tgcttccaga tcctgctagc cttggcccac gtactgtagg taaaaccaat
    19681 attggatgta tctttacagg tgtcaaagat ggcgttgaaa agactatcta catctacaat
    19741 gtttgcgacc atcaagagtg ctatgcagaa gtcgggtcac aagcaatttc atacacgaca
    19801 ggcgttccag ccatgattgg gacaaaatta gtcatgaacg gaacttggaa acaagctgga
    19861 gtgtataacc ttgaggagtt agatccagat ccattcatgg aagctttgaa tgagtatggt
    19921 ttgccatggg ttgtggttga aaatccacaa atggtggact aatgaagtta gaacaagtac
    19981 caacaccagc ctatgttatt gacttggcca agttagaagc taattgccgc attctacaat
    20041 atgtacaaga agaggtcggt tgcaaggtct tgcttgccca gaaggcatat tccctctaca
    20101 aaacttatcc cttgattagc cagtatctat caggtacgac agctagtgga ctctatgagg
    20161 ccaaattggc aagggaagaa tttcctggtg aagtccatgt atttgcgcct gctttcaagg
    20221 atgcagactt ggaggaattg cttgggataa cagaccatat cgtctttaac tcagagagac
    20281 agttgcgtaa gcatggggct cgttgtcgag aggctggtgt cagtgttggt ttgcgcctca
    20341 accctcagtg ttcaactcaa ggagatcacg cgctctatga cccttgtgca ccaggttctc
    20401 gctttggagt tactatagac aagattccga gtgatttgct agatttggtt gacggacttc
    20461 attttcatac cctttgcgag cagggagcag atgatttaca aacaactttg aaagcagtag
    20521 aagaacagtt tggtccctac ttacatgagg taaaatggct caatatgggt ggtggtcatc
    20581 atattacaag agaaggttac gatgtggatt tgctgatttc agaaatcaag cgtatccgaa
    20641 aaacttacaa tcttgaaatc tatatcgagc ctggtgaagc cattgcgctt aatgcgggtt
    20701 atttagcaac tgaggtatta gatattgtag aaaacggtat ggaaatcttg gttttagacg
    20761 cctctgcgac ctgccatatg cctgatgtac ttgagatgcc ctatcgtcca cctttgagaa
    20821 atggctttga ggcacaggaa aaagcccata cctacagact ttcttctaat acctgtctga
    20881 cgggcgatgt gattggtgat tatagttttg aaaatccagt ccaaatcgga gacagacttt
    20941 attttcaaga catggccatt tattcttttg tcaaaaataa tacctttaat ggtattggat
    21001 tgccaagtct ctatctcatg gacgaacagg gagactgtag cttactcaaa gcttttggct
    21061 atcaagactt taaagggaga ttatcatgat ggacagtcca aaaaaattag gctatcacat
    21121 gccagcagag tacgaacccc atcatggtac cctcatgata tggccgactc gaccaggatc
    21181 atggcctttt caaggaaagg atgctaaaag agcatttact cagatcatcg agactatagc
    21241 agaaggggaa agagtctatc ttttggtgga gcaggcctat ctatctgaag cccaatccta
    21301 tcttggggac aaggttgttt atttagacat tcccaccaat gatgcctggg cgcgtgatac
    21361 tggcccaacc attctcgtca atgataaagg taagaaatta gccgtggatt gggccttcaa
    21421 tgcttgggga ggcacctatg atggtcttta tcaagattat gaagaggatg accaagtagc
    21481 cagtcgtttt gctgaggcct tggaaaggcc tgtctatgat gctaaacctt ttgtactgga
    21541 aggaggtgca atccatagcg atggtcaagg aactattctc gtaactgaaa gttgcttgct
    21601 tagtcctggt cgcaatccta acttgactaa agaggagatt gaaaacacat tattagaaag
    21661 tcttggtgct gaaaaagtta tttggcttcc ttatggtatt tatcaggatg aaaccaatga
    21721 acacgtcgat aatgttgctg cctttgttgg tcctgctgag gttgttttgg cttggacaga
    21781 tgacgaaaat gatccccagt atgccatgtc aaaagcagat ctcgaactct tagaacagga
    21841 aacagatgca aaaggttgtc acttcaccat tcataaattg cctatccctg cagttcgaca
    21901 agttgtgaca gaagaagatt tgccaggcta catctatgaa gaaggagaag aagagcgata
    21961 cgcaggtgaa cgactagcag cttcctacgt aaacttttat atcgccaaca aggctgtctt
    22021 ggttccacag tttgaggatg taaacgacca agtggcctta gatatcctca gcaagtgttt
    22081 cccagaccgt aaagttgtcg gaataccagc cagagatatt ctcttaggtg gtggcaatat
    22141 ccactgtatc acccaacaaa ttccagaata ggagaaaaag atgagaaatg taagagttgc
    22201 aaccattcag atgcaatgcg ctaaggatgt ggcaacaaat atccaaaccg cagagcgttt
    22261 agtacgtcag gctgctgagc aaggagccca aattattctc ttgcccgagt tgtttgaaca
    22321 tccctatttc tgtcaggaac gtcagtatga ctactaccag tatgcccaat ctgtagcgga
    22381 aaatactgcc attcagcatt ttaaggtgat tgctaaggaa ctacaagttg ttttaccaat
    22441 cagtttctat gaaaaagatg gtaatgtctt gtataactct attgccgtca ttgatgcaga
    22501 tggggaagtg ctgggcgttt atcgaaagac ccatatacca gatgaccatt attatcaaga
    22561 aaaattctat ttcacgcctg gtaacactgg tttcaaggtc tggaatactc gctatgctaa
    22621 gattggtatc ggtatctgtt gggatcaatg gttccctgaa acagcgcgct gtcttgcatt
    22681 gaatggtgct gaattgctct tttatcctac agctatcggt tcagagccaa ttttggatac
    22741 agatagttgt ggtcactggc aacgtactat gcaagggcac gcagcagcga atattgttcc
    22801 agtcatcgca gccaatcgtt atggtttaga ggaggttact cctagtgagg aaaatggcgg
    22861 acagagttcc agtcttgact tctacggttc ctcctttatg acggatgaaa caggagctat
    22921 tctagaacga gctgaaagac aagaagaagc tgttctgtta gctacttatg acctagacaa
    22981 gggagcaagt gaacgtctaa actggggctt gtttcgagat agaaggccag aaatgtatag
    23041 acaaattaca gattagtgtg ggagaaatga gagattcatt ctgctagact aacttcttat
    23101 tagcaactat aagatactat ggcatctagt aaatcgattt ttatgattcg ctattcttgt
    23161 ctattgatta gtccgtattt taaatattag caaaaaagca aatagcagta acttctgtct
    23221 atttgctttt cttttttata gaatatattt ctcaatagca cgcgcaacgc cgtcttcttc
    23281 gttgcttgag gtaacggcat ccgcaagaga tttgacataa tcgctggcat ttcccattgc
    23341 aatcccaagc cctgcaaact ggagcatttc gatatcgtta ttagcatcgc ccatggccat
    23401 aatctctgag gaatcaatct tcaaaatctc agcaagtcgt gaaagagcag tagcctttgt
    23461 cgttccaagt ggcattgctt cataaatgac aggctgcgaa cgaactccac tgaatcgttg
    23521 gcaaagctct tcagcaaaac gctgctcaaa atcgtctgtt tgttcttttg ttcctaaaaa
    23581 cataccttgg aacatccgga actttccact agtcgcttct tcaagagaaa tttcagtcag
    23641 gtctgaaaat actagtttag catcattttc aataacttga ttgggcttgc caccgagaac
    23701 aaaataatgt gactcgtcaa aaagtgtcaa ctgaacatca ctcttttcag caaggtcata
    23761 gaggtattcg atgtcagctg gactcagttc ttgccagtca accaagcccc agtcgctagt
    23821 ctggtgagtt gaacaaccgt tgttaacaat cacatattcg ttctggaggt caagccccag
    23881 ttttttgtag taggggagga caccgaaaag ggggcgaccc gtacagagga ccagtttgac
    23941 acctttttca atggcttggt gaatagcagc gatgtgagcc tgtgggattt ccttggcttc
    24001 attgaggagg gttccatcca tatccaaggc tagtagttta atcataggtc ttccttcttt
    24061 atcttttggt attattatag catattttgg agaagaaatt gatagaaagc ttgagactaa
    24121 ttgattttat agtttaagat gttttgatga caattcatga tttgaagagg atatttggca
    24181 aagatatgct atactatgtt tgtcaatgtt gcaactagac aaattaaaaa accaacttaa
    24241 tataatagtt tttttgtaag taggtatgag tatcagatta ctcaactaat ctaaacaata
    24301 acggaggaaa tatatcatga ttttaatgac aaaaaatata aatctaacaa atgaagaatt
    24361 agagctgata caaggtggag cagatcccta tggtaaagaa cctaatggtt attatccttg
    24421 gcaaatggaa ccagtattaa ctatgccggt tcatggattt tgtcccagag gaaccgatga
    24481 tttagtatat attgtaggag gtaatcatct ttgcaaagga agtgctgcga gattttaagt
    24541 aaaatttatt aggaatatga agaaacaagg ggagaaaaca gaggatttaa tatgaaaaaa
    24601 cgagctattc aaattttact agcattgtcc ttaatttttt acaaatcaac ttggttttgg
    24661 aggcttttca attatctcgc aaagccctat ctaccagcaa gtcgtgaatt ttttcagatt
    24721 ctacttttgc tggaaagtgg tgttcttttg tcagcagtca tctatctact agtttttgca
    24781 ggaaagaaga tttttcattt caagtggcag ttgaggtact ttatctacct tttactgggc
    24841 tacatcattt cgtatatgtc tgactttctc ttttcgtatt tcatatcccc gccttcaaat
    24901 caaatttctt tgaatgaaac gatagaaatg atgggacgac aggagttccc ttatttcttg
    24961 ctcatcgttt gcttcatcgc ccctattgct gaggaattga tttatcgcgg tgtgattatg
    25021 acaacctttt tcaaaaactc gccttggtac ggagatgttt tgctttctgc tattattttc
    25081 ggttatattc atatcaattt tgctttaact cctcttgctt ttttcattta tgctagtgga
    25141 ggtcttattt tagctctatt gtatcgcatg actaaaaatc tctactatcc aatactagtt
    25201 catattctca tcaatatcac tgccttctgg gatgtgtggt tactcctatt ttcaggaagt
    25261 tagcttacta aaaaaatgtc ggaattttcc ggcattttct tttttcacaa atagtcaacg
    25321 tttttctttc cgatactgaa gtggtgtgta gccacttatt tttttgaatt gattttgaaa
    25381 ataagattgg cgtgagaaag gcagatagtg aagatagtta agaagaatag gatgttcttt
    25441 tttccttttt ggaaaacttc taaaatatgg tataatgaaa agataaagaa gttgggggta
    25501 gaagatgaac attcaacaat tacgctatgt tgtggctatt gccaatagtg gtacttttcg
    25561 tgaagctgct gaaaagatgt atgttagtca gccgagtctg tctatttctg ttcgtgattt
    25621 ggaaaaagag ttgggcttta agatttttcg tcggaccagc tcagggactt tcttgacccg
    25681 tcgtgggatg gaattttatg aaaaagcgca agaattggtt aaaggatttg atatttttca
    25741 aaatcagtat gccaatcctg aagaagaaaa agatgaattt tccgttgcta gccagcacta
    25801 tgacttctta ccaccaacta ttacggcctt ttcagagcgc tatcctgact ataagaactt
    25861 ccgtattttt gaatcaacta ctgttcaaat attagatgaa gtggcgcaag ggcatagtga
    25921 gattgggatt atctacctca acaatcaaaa taaaaagggg attatgcaac gggttgaaaa
    25981 gttaggtctg gaggtcatcg aattgattcc tttccatacc catatttatc tctgtgaggg
    26041 tcatccttta gcccagaaag aggaattagt catggaggat ttagcggatt taccaacggt
    26101 tcgtttcact caagagaaag acgagtacct ttattattca gagaactttg ttgataccag
    26161 cgctagctca cagatgttta atgtgacaga ccgtgccacc ttgaatggta ttttggagcg
    26221 gacggacgcc tatgcgacag gttctggatt tttagatagt gacagtgtta atggcattac
    26281 agttattcgt ctcaaggata acctagataa ccgcatggtc tatgttaaac gtgaagaagt
    26341 ggagcttagt caagctggga ctctcttcgt agaagtcatg caagaatatt ttgatcaaaa
    26401 gaggaaatca tgaaaaaaag agcaatagtg gcagtcattg tactgctttt aattgggctg
    26461 gatcagttgg tcaaatccta tatcgtccag cagattccac tgggtgaagt gcgctcctgg
    26521 attcccaatt tcgttagctt gacctacctg caaaatcgag gtgcagcctt ttctatctta
    26581 caagatcagc agctgttatt cgctgtcatt actctggttg tcgtgatagg tgccatttgg
    26641 tatttacata aacacatgga ggactcattc tggatggtct tgggtttgac tctaataatc
    26701 gcgggtggtc ttggaaactt tattgacagg gtcagtcagg gctttgttgt ggatatgttc
    26761 caccttgact ttatcaactt tgcaattttc aatgtggcag atagctatct gacggttgga
    26821 gtgattattt tattgattgc aatgctaaaa gaggaaataa atggaaatta aaattgaaac
    26881 tggtggtctg cgtttggata aggctttgtc agatttgtca gaattatcac gtagtctcgc
    26941 gaatgaacaa attaaatcag gccaggtctt ggtcaatggt caagtcaaga aagctaaata
    27001 cacagtccaa gagggtgatg tcgtcactta ccatgtgcca gaaccagagg tattagagta
    27061 tgtggctgag gatcttccgc tagaaatagt ctaccaagat gaggatgtgg ctgtcgttaa
    27121 caaacctcag ggaatggttg tgcacccgag tgctggtcat accagtggaa ccctagtcaa
    27181 tgccctcatg tatcatatta aggacttgtc gggtatcaat ggggttctgc gtccagggat
    27241 tgttcaccgt attgataagg atacgtcagg tcttctcatg attgctaaaa acgatgatgc
    27301 gcatctagca cttgcccaag aactcaagga taaaaagtct ctccgcaaat attgggcgat
    27361 tgttcatgga aatctgccta atgatcgtgg tgtaattgaa gcgccgattg gccggagtga
    27421 aaaagaccgt aagaaacagg ctgtaactgc taaagggaag cctgcagtga cgcgttttca
    27481 cgtcttggaa cgctttggcg attatagctt agtagagttg caactggaga cagggcgcac
    27541 tcatcaaatc cgtgtccaca tggcttatat cggccattca gtcgctggtg atgaggtcta
    27601 tggtcctcgc aagactttga aaggacatgg acaatttctt catgccaaga ctttaggttt
    27661 tactcatccg agaacaggta agaccttgga atttaaagca gatatcccag agatttttaa
    27721 ggaaaccttg gagagattga gaaagtaaga atgaaaaaga aattaactag tttagcactt
    27781 gtaggcgctt ttttaggttt gtcatggtat gggaatgttc aggctcaaga aagttcagga
    27841 aataaaatcc actttatcaa tgttcaagaa ggtggcagtg atgcgattat tcttgaaagc
    27901 aatggacatt ttgccatggt ggatacagga gaagattatg atttcccaga tggaagtgat
    27961 tctcgctatc catggagaga aggaattgaa acgtcttata agcatgttct aacagaccgt
    28021 gtctttcgtc gtttgaagga attgggtgtc caaaaacttg attttatttt ggtgacccat
    28081 acccacagtg atcatattgg aaatgttgat gaattactgt ctacctatcc agttgaccga
    28141 gtctatctta aaaaatatag tgataatcgt attactaatt ctgaacgtct atgggataat
    28201 ctgtacggtt atgataaggt tttacagact gctgcagaaa aaggtgtttc agttattcaa
    28261 aatatcacac aaggggatgc tcattttcag tttggggaca tggatattca gctctataac
    28321 tatgaaaatg aaaccgattc atcgggtgaa ttaaagaaaa tttgggatga taattccaat
    28381 tccttgatta gtgtggtaaa agtcaatggc aagaaaattt accttggggg cgacttagat
    28441 aatgttcatg gagcagaaga caagtatggt cctctcattg gaaaagttga tttgatgaag
    28501 tttaatcatc atttagatac aaaaaattct aatacaaaaa attttataaa aaatttgtct
    28561 cctgagataa ttgttcaaac ttcctcctca ccaattggtt cgtatgatag cggtcaagaa
    28621 ataaataggg aatatattag ttggcttgaa tcaatgggaa ttcaacatat aaatgcagcc
    28681 agcaaagact atgatgcaac agtttttgat attcgacaag acggtttaat aaacatttca
    28741 acttcctaca agcctattcc aagttttcaa gctggttggc ataagagttc atatggaaac
    28801 tggtggtatc aagcgcctga ttctacagga gaatatgctg ttggttggaa tgaaattaag
    28861 ggtgaatggt attactttaa ccaaacgggt atcttattac agaatcaatg gaaaaaatgg
    28921 aacaatcgtt ggttctattt gacagactct ggtgttgctg ctaaaaattg gaagaaaatc
    28981 gctggaatct ggtattattt taacaaagaa aaccagatgg aaattggttg gattcaagat
    29041 aaagagcagt ggtattattt ggatgttgat ggctctatga agacaggttg gcttcaatat
    29101 aaggggcaat ggtattactt tgctccatca ggggaaatga aaacgggctg ggtaaaagat
    29161 aaagaagcct ggtactatat ggattctact ggtatcatga agacaggtga gatagaagtt
    29221 gctggacatc attactatct agaagaatca ggagctatga agcaaggctg gcataaaaag
    29281 gcaaatgatt ggtatttcta caagacagac ggttcacgag ctgtgggttg gatcaaggac
    29341 aaggataaat ggtacttctt gaaagaaaat ggtcaattac ttgtgaacgg taagacacca
    29401 gaaggctata ctgtggattc aagtggtgcc tggttagtgg atgtttcgat cgagaaatct
    29461 gctacaatta aaactacaag tcattcagaa ataaaagaat ccaaagaagt agtgaaaaag
    29521 gatcttgaaa ataaagaaac gagtcaacat gaaagtgtta caaattcttc aactagtcaa
    29581 gatttgacat cctcaacttc acaaagctct gaaacgagtg taaacaaatc ggaatcagaa
    29641 cagtagtaga aaagaaggtt ttagggcctt ctttttccta tcaactcttt tctatttcct
    29701 gttattcatg ttataatgga taaatatgaa taatcggagt gagactatga aatacaaacg
    29761 gattgtcttt aaggtgggta cttcttctct gacaaatgag gatggaagtt tatcacgtag
    29821 taaggtaaag gatattaccc agcagttggc tatgctgcac gaggctggtc atgagttgat
    29881 tttggtgtct tcaggtgcca ttgcggctgg ttttggagcc ttaggattta aaaagcgtcc
    29941 gactaagatt gctgataaac aggcttcagc agcggtaggg caagggcttt tgttggaaga
    30001 atatacaacc aatcttctct tgcgtcaaat cgtttctgca caaatcttgc tgacccaaga
    30061 tgattttgtg gataagcgtc gttataaaaa tgcccatcag gctttgtcgg ttttactcaa
    30121 tcgtggggca attcctatca tcaatgagaa tgatagtgtc gttattgatg aggtcaaggt
    30181 tggggacaat gacactctaa gtgcccaagt agcggcgatg gtccaagcag accttttggt
    30241 tctcttgaca gatgtggacg gtctctatac tggaaatcct aattcagatc caagagccaa
    30301 acgcttggag agaatagaga ccatcaatcg tgagattatt gatatggctg gtggagctgg
    30361 ttcgtcaaac ggaactgggg gtatgttaac caaaatcaag gctgcaacta tcgcgacgga
    30421 atcaggagtt cctgtttata tctgctcatc cttgaaatca gattccatga ttgaggcggc
    30481 agaggagacc gaggatggtt cttactttgt tgctcaagag aaggggcttc gtacccagaa
    30541 acaatggctt gccttctatg ctcagagtca aggttctatt tgggttgata aaggggctgc
    30601 ggaagctctc tctcaacatg gaaagagtct tctcttatct ggtattgttg aagcagaagg
    30661 agccttttct tacggtgata tagtgacagt atttgacaag gaaagtggaa aatcacttgg
    30721 aaaaggacgc gtgcaatttg gagcatctgc tttggaggat atattgcgtt ctcaaaaagc
    30781 caagggtgtc ttgatttacc gtgacgactg gatttccatt actcctgaaa tccaactact
    30841 ttttacagaa ttttagaggt aaactatggt gagtagacaa gaacaatttg aacaggtaca
    30901 ggctgttaaa aaatcgatta acacagctag tgaagaagtg aaaaatcaag ccttgctagc
    30961 catggctgat cacttagtag ctgctactga ggaaatttta gcggctaatg ccctcgatat
    31021 ggcagcggct aaggggaaaa tctcagatgt gatgttggat cgtctttatt tggatgcaga
    31081 tcgtatagaa gcgatggcaa gaggaattcg tgaagtggtt gccttaccag atccaatcgg
    31141 tgaagtttta gaaacaagtc agcttgaaaa tggtttggtt atcacaaaaa aacgtgtagc
    31201 tatgggtgtc atcggtatta tctatgaaag ccgtccaaat gtgacgtctg atgcggctgc
    31261 tttgactctt aagagtggaa atgcggttgt tcttcgtagt ggtaaggatg cctatcaaac
    31321 aacccatgcc attgtcacag ccttgaagaa gggcttggag acgactacta ttcacccaaa
    31381 tgtgattcaa ctggtggaag atactagcca tgaaagtagt tatgctatga tgaaggccaa
    31441 gggctatcta gacctcctca ttcctcgtgg aggagctggc ttgatcaatg cagtggttga
    31501 gaatgcgatt gtacctgtta tcgagacagg gactgggatt gtccatgtct atgtggataa
    31561 ggatgcagac gaagacaagg cgctgtctat catcaacaat gctaaaacca gtcgtccttc
    31621 tgtttgtaat gccatggagg ttctgctggt tcatgaagat aaggcagcaa gcatccttcc
    31681 tcgcttggat caaatgctgg ttgcagagcg taaggaagct ggactggaac caattcaatt
    31741 ccgcttggat agcaaagcaa gccagtttgt ttcaggtcaa gcagctgaga cccaagactt
    31801 tgacaccgag tttttagact atgtccttgc tgttaaggtt gtgagcagtt tagaagaagc
    31861 ggttgcgcac attgaatccc acagcaccca tcattcggat gctattgtga cggaaaatgc
    31921 tgaagctgca gcatacttta cagatcaagt ggactctgca gcggtgtatg ttaatgcctc
    31981 aactcgtttc acagatggag gacaatttgg tcttggttgt gaaatgggga tttctactca
    32041 gaaattgcac gcgcgtggtc caatgggctt gaaggaattg actagctaca agtatgtggt
    32101 cactggtgat ggacagataa gggagtaaga gatgaagatt ggatttatcg gtttggggaa
    32161 tatgggtgct agtttagcca agtctgtctt gcaggctaga ccgtcagatg agattctcct
    32221 tgccaatcgt agtcaagtca aggtggatgc tttcatcgct aacttcggtg gtcagacttc
    32281 taacaatgaa gaaatattcg aagaagcaga tgtgattttt ctaggtgtta agcctgctca
    32341 gttttctgaa ctgctttctc aataccagac catccttgaa aaaagagaaa gtcttctttt
    32401 gatttcgatg gcagctggat tgatcttaga aaaactagca agtcttatcc caagccaaca
    32461 ccgaattatt cgtatgatgc ctaatacccc tgcttctatc gggcaaggag tgattagtta
    32521 tgccttgtct cctaattgca gggctgagga cagtgagctc ttttgtcagc ttttatccaa
    32581 ggctggtctc ttggttgaat taggagaaag cttaatcaat gcagcgacag gtcttgcagg
    32641 ctgtggacca gcctttgtct atctctttat tgaggccttg gcagatgcag gtgttcagac
    32701 gggattacca cgagaaacag ccttgaaaat ggcagcccaa actgtggtag gagctgggca
    32761 attggtccta gaaagccagc aacatcctgg agttttgaaa gatcaagttt gtagtccagg
    32821 cggttcgact attgctggcg tagcaagcct agaagcgcat gcttttcgag gaacggtcat
    32881 ggaggcagtt catcaagcct ataaacgaac acaagaacta ggtaaataag aggtagtttt
    32941 atctgcctct tttatggtgg ttgatactct tcgaaaatca aattcaaact gcgtcagctt
    33001 caccttgccg tactcaagta cagcctgcgg ctagcttcct agtttgctct ttgattttca
    33061 ttgagtatga aatgagaaga caaaaagatt gtcacaaacc cctatttttt tgatagaata
    33121 gaagtagtaa aaaagaaatg agttagacat gtcaaaagga tttttagtct ctcttgaggg
    33181 accagaggga gcaggcaaga ccagcgtttt agaggctctg ctaccaattt tagaggtaaa
    33241 aggggtaaag gtgctgacga cccgtgaacc tggcggagtc ttgattgggg agaagattcg
    33301 ggaagtgatt ttggatccaa gtcatactca gatggatgct aaaacagagc tacttctcta
    33361 tattgccagt cgcagacagc atttggtgga aaaagttctt ccagcccttg aagctggcaa
    33421 gttggtcatc atggatcgtt ttatcgatag ttctgttgcc tatcagggat ttggtcgtgg
    33481 cttagatatt gaagccattg actggctcaa tcagtttgcg acagatggcc tcaaacccga
    33541 tttgacactc tattttgaca tcgaggtgga agaagggctg gctcgtattg ctgctaatag
    33601 tgaccgcgag gttaatcgtt tggatttgga agggttggac ttgcataaaa aagttcgtca
    33661 aggctacctt tctctcctgg aaaaagaagg aaatcgcatt gtcaagattg atgctagtct
    33721 ccctttggag caagttgtgg aaactaccaa ggctgtcttg tttgacggaa tgggcttggc
    33781 caaatgaaac aagatcaact aaaggcttgg caaccagctc agtttgaccg ttttgtccgt
    33841 atcttagaac aagaccagct caatcacgcc tatctctttt caggtttctt tggaagcttg
    33901 gaaatggcgc aatttttagc taagagcctc ttttgtacgg ataaagttgg cgtcttacca
    33961 tgtgagaaat gccgaagttg caagctgatt gaacaggaag agtttccaga tgtcaccttg
    34021 attaagccag tcaatcaggt catcaagaca gaacgcattc gggaattggt gggacagttt
    34081 tctcaagcag ggattgaaag ccagcaacag gtctttatca tcgagcaagc ggataaaatg
    34141 catcccaacg cagccaattc tctgctcaag gtcatcgaag aaccccagag tgaagtttat
    34201 attttcttct tgactagcga tgaggaaaag atgttaccga caatccgaag tcggactcag
    34261 atcttccact ttaaaaagca agaagaaaaa cttatcttac tcttagaaca aatgggactt
    34321 gttaagaaaa aagcgactct tttagctaag tttagtcaat cgcgagctga agcagaaaag
    34381 ttggctaatc aggcaagttt ttggaccttg gtcgatgaaa gtgaacgcct gctgacttgg
    34441 ttagtagcta agaaaaaaga aagttatcta caggttgcca aattagccaa cttggcagat
    34501 gataaggaaa aacaggatca ggttttacgg attcttgaag ttctctgtgg gcaggacctc
    34561 ttgcaggtaa gagtaagagt gattctacaa gatttactag aagctagaaa aatgtggcaa
    34621 gctaatgtca gctttcaaaa tgccatggaa tatctggtct tgaaagaaat ataaactcaa
    34681 aaatgaatga taaagaaagg aaagggctgt tttatggaca aaaaagaatt atttgacgcg
    34741 ctggatgatt tttcccaaca attattggta actttagccg atgtggaagc catcaagaaa
    34801 aatctcaaga gcttggtaga agaaaataca gctcttcgct tggaaaatag taagttgcga
    34861 gaacgcttgg gtgaggtgga agcagacgct cccgtcaagg ccaagcatgt tcgcgaaagt
    34921 gtccgtcgta tttaccgtga tggatttcac gtatgtaatg atttttatgg acaacgtcga
    34981 gagcaggacg aagaatgtat gttctgtgat gagttgttat acagggagta agcatgcaga
    35041 ttcaaaaaag ttttaagggg cagtctccct atggcaagct gtatctagtg gcaacgccga
    35101 ttggcaatct agatgatatg acttttcgtg ctatccagac cttgaaagaa gtggactgga
    35161 ttgctgctga ggatacgcgc aatacaggtc ttttgctcaa gcattttgac atttccacca
    35221 agcagatcag ttttcatgag cacaatgcca aggaaaaaat tcctgatttg attggtttct
    35281 tgaaagcagg gcaaagtatt gctcaggtct ctgatgccgg tttgcctagc atttcagacc
    35341 ctggtcatga tttggttaag gcagctattg aggaagaaat tgcagttgtt acagttccag
    35401 gtgcctctgc aggaatttcc gccttgattg ccagtggttt agcgccgcag ccacatatct
    35461 tttacggctt tttaccgaga aaatcaggcc agcaaaagca atttttcgac tcgaaaaaag
    35521 actatcctga aactcagatt ttttatgaat cgccccatcg tgtggcagat acattggaaa
    35581 atatgctaga agtctacggt gaccgctcgg tagtcttggt tagagaattg accaaaatct
    35641 atgaagaata ccaaagaggt acaatttctg aattgctgga aagcatctct gaaacgtctc
    35701 tcaagggtga atgtcttctg attgttgaag gtgccagcaa aggtgtggag gaaaaggatg
    35761 aggaagactt gttcttagaa atccaagccc gtatccagca aggcatgaag aaaaatcaag
    35821 ctattaagga agtcgctaag atttaccagt ggaataaaag tcagctctac gctgcctacc
    35881 acgactggga agaaaatcaa gaaaatgact aaacagggaa gtttgccttc ttcccttttt
    35941 ttgttatact agtagaagaa aaaattagaa agatttgtgg gtgttaaaca agccagtgcc
    36001 ttgttttgat atgaacttag gttccaccca aagaggtatt agtgtcgtgt ctcaatctta
    36061 tatcaatgtt atcggtgctg gtttggcagg ttctgaagca gcttaccaaa tcgcagagcg
    36121 tggtattcca gttaaactat atgaaatgcg tggtgtcaag tctacacccc agcataaaac
    36181 agacaatttt gctgagttgg tttgttccaa ttctttgcgt ggggatgctt tgacaaatgc
    36241 agttggtctt ctcaaggaag aaatgcgtcg cttgggttct gttatcttgg aatctgctga
    36301 ggctacacgt gttcctgccg gtggagccct tgcggtggat cgtgatggtt tctctcaaat
    36361 ggtgaccgaa aaagttgcca accacccctt gattgaagtg gttcgtgatg aaattacaga
    36421 attgccgaca gatgttatta cggttatcgc tactggtcct ttgacaagtg atgccttgac
    36481 tgaaaagatt catgccctta atgacggtga tggtttttat ttctacgatg cggcagcgcc
    36541 tattatcgat gtcaacacta tcgatatgag caaggtctac ctcaaatcac gttatgataa
    36601 gggagaagcg gcctacctca atgcccctat gaccaagcaa gaatttatgg atttccatga
    36661 agctttggtc aatgcagaag aagcaccgct taattctttt gaaaaagaaa agtactttga
    36721 aggatgtatg cctatcgaag ttatggccaa acgtggcatt aaaactatgc tttatggccc
    36781 tatgaagcca gtcggtcttg agtatccgga cgactacaca ggacctcgtg atggagaatt
    36841 taaaacacct tatgcggttg tgcaacttcg tcaggataat gcagctggta gcctctacaa
    36901 tatcgttggt ttccagaccc acctcaaatg gggagaacaa aagcgtgtct tccaaatgat
    36961 tccgggtctt gaaaatgcgg agtttgtccg ttatggtgtc atgcatcgca attcttacat
    37021 ggattcacca aatcttcttg agcagactta ccgttccaag aaacaaccaa atctcttctt
    37081 tgctggtcag atgacggggg tggaaggcta tgttgagtcg gcggcttcgg gcttagttgc
    37141 gggaattaac gcagctcgtc tcttcaagga agaaagcgag gttattttcc ccgagacgac
    37201 agcgattgga agcttagctc attacattac ccatgccgac agcaaacatt tccaaccaat
    37261 gaatgtcaat tttgggatca tcaaggagtt ggaaggcgag cgtatccgtg ataagaaggc
    37321 tcgttatgaa aaaattgcag agcgtgccct tgccgactta gaggaatttt tgactgtcta
    37381 atttttttga aagaattgct catgatacta taaaaatctt agaaattgtg ataaaatagg
    37441 taggatgaaa gaaggagagt gaaaatggcg aatcccaagt ataaacgtat tttaatcaag
    37501 ttatcaggtg aagcccttgc cggtgaacgt ggcgtaggga ttgatatcca aacagttcaa
    37561 acaatcgcaa aagagattca agaagttcat agcttaggta tcgaaattgc gcttgttatt
    37621 ggtggaggaa atctctggcg tggagaacct gcagcagaag caggtatgga ccgtgttcag
    37681 gcagattaca ctggaatgct tgggactgtt atgaatgctc ttgtgatggc agattcattg
    37741 caacaagttg gggttgatac gcgtgtacaa acagctattg ctatgcaaca agtggcagag
    37801 ccttatgtcc gtggacgtgc ccttcgtcac cttgaaaaag gccgtatcgt tatctttggt
    37861 gctggaattg gttcaccata cttctcgaca gatacaacag cggcccttcg tgcagctgaa
    37921 atcgaagcag atgccatcct catggctaaa aatggcgtcg atggtgtgta caatgccgat
    37981 cctaagaagg acaagacagc cgttaagttt gaagaattga cccaccgtga tgttatcaac
    38041 aaaggtcttc gtatcatgga ctcaacagcc tcaaccctct caatggacaa cgacattgac
    38101 ttggttgtct tcaacatgaa ccaatcaggc aacatcaaac gtgtcgtatt tggtgaaaat
    38161 atcggaacaa cagtttcaaa taatatcgaa gaaaaggaat aagaaagaat atggctaacg
    38221 taattattga aaaagctaaa gagagaatga cccagtctca ccaatcactt gctcgtgaat
    38281 ttggtggtat ccgtgctggt cgtgccaatg caagcttgct tgaccgtgta catgtagaat
    38341 actatggagt cgaaactcct cttaaccaaa tcgcttcaat tacgattcca gaagcgcgtg
    38401 ttttgttggt aacaccattt gacaagtctt cattgaaaga catcgaacgt gccttgaacg
    38461 cttctgatct tggtatcaca ccggctaatg acggttctgt gattcgcttg gttatcccag
    38521 ctcttacaga agaaactcgt cgtgaccttg ctaaagaagt gaagaaggtc ggcgaaaatg
    38581 ctaaagtggc tgtccgcaat atccgtcgcg atgctatgga cgaagctaag aaacaagaaa
    38641 aagcaaaaga aatcactgaa gacgaattga agactcttga aaaagatatt caaaaagtaa
    38701 cagacgatgc tgttaaacac atcgacgata tgactgccaa caaagagaaa gaacttttgg
    38761 aagtctaaaa ataaacagaa aaactcagtt ggcattgctg gctgagtttt attcgaaaga
    38821 aggaaatatg aatacaaatc ttgcaagttt tatcgttgga ctgatcatcg atgaaaacga
    38881 ccgtttttac tttgtgcaaa aggatggtca aacctatgct cttgctaagg aagaaggcca
    38941 acatacagta ggggatacgg tcaaaggttt tgcatacacg gatatgaagc aaaaactccg
    39001 cctgacaacc ttagaagtga ctgccactca ggaccaattt ggttggggac gtgtcacaga
    39061 ggttcgtaag gacttgggtg tctttgtgga tacaggcctt cctgacaagg aaatcgttgt
    39121 gtcactcgat attctccctg agctcaagga actctggcct aagaagggcg accaactcta
    39181 catccgtctt gaagtggata agaaagaccg tatctggggt ctcttggctt atcaagaaga
    39241 cttccaacgt cttgctcgtc ctgcctacaa caacatgcag aaccaaaact ggccagccat
    39301 tgtttaccgt ctcaagctat caggaacttt tgtttaccta ccagaaaata atatgcttgg
    39361 ttttattcat cctagcgagc gttacgcaga gccacgtttg gggcaagtat tagatgcgcg
    39421 cgttattggt ttccgtgaag tggaccgcac tttgaacctc tccctcaaac cacgctcctt
    39481 tgaaatgttg gaaaacgatg ctcagatgat tttgacttat ttggaaagca atggcggttt
    39541 catgacctta aatgacaagt catctccaga cgacatcaag gcaacctttg gcatttctaa
    39601 aggtcagttc aagaaagctt taggtggtct tatgaaggct ggtaaaatca agcaggacca
    39661 gtttggtaca gagttgattt agggaggctt atgagaaaat cattttacac ttggctcatg
    39721 accgagcgca atcctaaaag taacagtccc aaagcaattt tggcagacct cgcttttgaa
    39781 gagtcagcct ttccaaaaca tacagatgat tttgatgagg tcagtcgctt tttggaggag
    39841 catgccagtt tctcttttaa cctaggagat tttgacagca tttggcagga atatctagaa
    39901 cactagcatt tattcattgg gtttgggcta gtaatttctc catccctctg ctataataaa
    39961 aagaaataaa aggattagag aggttcttta tttgaaggaa cattcaatag acattcaact
    40021 gagtcatcca gatgacctgt ttcatctttt tggttccaat gaacgccatc ttcgtttgat
    40081 ggaagaagag cttgatgttg tgattcatgc tcgtacggag attgtccagg ttttgggaga
    40141 agagtctgcc tgtgaggaag cccgtcaagt tattcaggct ttgatggtct tggtaaatcg
    40201 tgggatgacc gttggtacgc cagatgtagt cactgcgatt agcatggtca aaaatgatga
    40261 aattgacaag tttgtcgccc tttacgaaga agaaattatc aaagataata ctgggaaacc
    40321 tatccgtgtc aaaaccctag ggcaaaagct ttatgtggac agtgtcaaac agcatgatgt
    40381 gacctttgga attgggccag caggtacagg gaagaccttc cttgcagtga ccttggcagt
    40441 gactgccctt aaacgtgggc aagtcaagcg aattatccta actcgtccag cggtggaagc
    40501 gggagagagt cttggatttc ttccgggtga tcttaaagag aaggtggatc cttaccttcg
    40561 tcctgtttac gatgccttgt atcaaattct tgggaaagac caaacgactc gtctcatgga
    40621 gcgtgaaatt atcgaaattg cgccccttgc ctatatgcgt ggtcggacct tggatgatgc
    40681 ctttgtcatt ctcgatgagg cgcaaaatac gaccatcatg cagatgaaga tgttcttgac
    40741 tcgtttaggt tttcattcta agatgattgt caatggagat attagtcaga ttgatctgcc
    40801 acgtaatgtc aagtccggtt tgattgatgc ccaagaaaag ctcaagaaca tttaccaaat
    40861 tgactttgtt catttttcag ctaaggatgt ggttcgccat ccagttgtcg ctcagattat
    40921 ccgagcttat gaaccagctc cagttaaaaa agaagagagt gaagaattag agtctcaacc
    40981 tctgtctgaa ggatagttct tttgtactta aagttatctc aatgctaagt ataaatttgc
    41041 tttttaaatg ttttattcaa tatccttata ttagattaga aacgtttcaa gcggaggaaa
    41101 cgtatggaat caatatttgt gaaatttgcc cagtatccgt ctatagaaac ggagcgttta
    41161 ttgcttagac ctgtaacttt ggatgatgcg gaagcaatgt ttgactatgc ctcggacaag
    41221 ggtaatacac gttacacttt tccaaccaat caaagcttgg aagaaaccaa gaataacatt
    41281 gctcagttct atttggctaa tcccttggga cgttggggaa tagaactaaa aagcaatggt
    41341 cagtttattg gaaccattga cttgcacaag attgattctg ttcttaagaa ggcagctatt
    41401 ggctacatta tcaataaaaa gtattggaat caaggattaa cgacagaagc caatcgtgct
    41461 gtgattgagc tagcttttga gaagataggg atgaataagt tgactgccct tcacgataag
    41521 gacaatcctg cgtcaggaaa ggtcatggag aaatcaggca tgcgtttttc ccatgcagaa
    41581 ccatatgctt gtatggacca gcatgaaaaa gatcgaatcg ttacaagagt tcattatgtc
    41641 ttgaccaagg aagactattt tgcaaataaa taagcagttg aaaagaaatt tttcgactgt
    41701 tttttcttcc tcttacgaat aatctaagag aggagaaaat atggaagcaa ttatcgagaa
    41761 aatcaaagag tataaaatca tcgtcatctg tactggtctg ggcttgcttg taggcggatt
    41821 tttcctgcta aagccagctc cacaaacacc tgtaaaggaa acgaatttgc aggctgaagt
    41881 tgcagctgtt tccaaggatt tggtatccga aaaggaagtg aacaaggaag agaaggaaga
    41941 accagttgaa caagatctaa tcacagtaga tgtcaaaggt gctgtcaaat cgccagggat
    42001 ttatgacttg cctgtaggta gtcgagtcaa tgatgctgtt cagaaggctg gtggcttgac
    42061 agagcaagca gacagcaagt cgctcaatct agctcagaaa gttagtgatg aggctctggt
    42121 ttacgttcct actaagggag aagaagcagt tagtcaacag actggttcgg ggacagcttc
    42181 ttcaataagc aaggaaaaga aggtcaatct caacaaggcc agtctggaag aactcaagca
    42241 ggtcaaggga ctgggaggaa aacgagctca ggacattatc gaccatcgtg aggcaaatgg
    42301 caagttcaag tcagtagacg agctcaagaa ggtctctggc attggtggca aaacaataga
    42361 aaagcttaaa gactatgtta cagtggatta agaatttctc tattccccta atttacctga
    42421 gttttctatt actttggctt tattacgcta ttttctcagc atcttatctt gctttgttgg
    42481 gctttgtttt tctgctagtc tgtctcttta tccaatttcc gtggaaatct gctggtaaag
    42541 ttctaataat ttgcggaatc tttggatttt ggtttgtttt tcaaaattgg caacagagtc
    42601 aagcgagtca aaatctggcg gattctgttg aaagggtacg gattttgcct gatactatta
    42661 aggttaatgg tgatagtcta tcctttcgtg gcaagtctaa cggtcgtgct ttccaagtct
    42721 attataaact ccagtccgag gaggagaaag aagcctttca agctttaacc gacctgcatg
    42781 agataggact agaagggaag ctttcggagc cagaagggca gagaaatttt ggtggcttta
    42841 attaccaagc ctatctgaag actcagggaa tttaccagac tctcaatatc aaaacaatcc
    42901 agtcacttca aaagattggc agttgggata taggagaaaa cttgtccagt ttacgtcgaa
    42961 aggctgtggt ttggattaag acgcactttc cagaccctat gcgcaattac atgacaggac
    43021 tcttgctggg acatctggac accgactttg aggagatgaa tgagctttat tccagtctag
    43081 gaattatcca cctctttgcc ctatctggta tgcaggtagg ttttttcatg aatggattta
    43141 agaaacttct cttgcgattg ggcttgaccc aagaaaagtt gaaatggctg acttatccct
    43201 tttcccttat ctatgcggga ctaactggat tttcagcatc ggttattcgc agtctcttgc
    43261 aaaagctact ggctcaacat ggggttaagg gcttggataa ttttgccttg acggtgcttg
    43321 tcctctttat tgtcatgcca aactttttct tgacagcagg aggagtcttg tcctgcgctt
    43381 atgcttttat cctgaccatg accagcaaag aaggggaggg gctcaaggct gttactagtg
    43441 aaagtctagt catctccttg ggcatattgc ccattctatc cttctatttt gcggaatttc
    43501 aaccttggtc tatccttttg acctttgtct tttcctttct atttgacttg accttcttac
    43561 cgctcttgtc tattttattt gtcctttcct ttctctatcc agtcattcag ctgaacttta
    43621 tctttgaatg gttggagggc attattcgct tggtgtcaca ggtgacaagt agacctctgg
    43681 tctttggaca acccaatgca tggtttttaa tcctattgtt aatttccttg gctttggtct
    43741 atgatttgag aaaaaacatt aaaaagctaa cggtattgtg cttattgatt acagggctct
    43801 ttctcctgac caagcatcca ctggaaaatg aaatcaccat gctggatgtg gggcaaggag
    43861 aaagtatttt cctacgggat gtaactggga aaaccattct catagatgta ggtggtaagg
    43921 cagaatctta taagaaaatc gaaaaatggc aagaaaagat gacgaccagc aatgcccagc
    43981 gaaccttgat tccctatctc aaaagtcgag gagtagctaa gattgaccag ctaattttga
    44041 ctaacacgga caaggagaat gttggagatt tgtcagaggt gaccaaggct ttccatgtag
    44101 gggagattct agtatcaaaa gacagtctga aacagaagga atttgtggca gaactacaga
    44161 cgactcaaac aaaggtgcgt agtatgacag taggggagaa cttgcccatt tttggaagtc
    44221 agttagaagt tctatctcca aggaaaatgg gagatggagg acacgatgac accctagttc
    44281 tgtatgggaa attcttggat aagcaatttc tcttcacggg aaatttggag gagaaaggag
    44341 agaaggactt gctgaagcac tatccagact tgaaagtaaa tgttttgaaa gctagccaac
    44401 atggcaataa aaaatcatca agtccagcct ttctagaaaa actcaaacca gagcttactc
    44461 ttatctcagt tggaaagagc aatcgaatga aactccccca tcaggaaaca ttgacacgac
    44521 tggaaggtat caatagcaaa gtttatcgaa ctgaccagca aggagctata cgttttaagg
    44581 ggttggatag ttggaaaatc gaaagtgttc gataggaagg ataaatgttg tagattagtg
    44641 aaataaacta aaaatttgtt gcataataat gataaaaatg gtataatgaa aacgtattca
    44701 atattgagga tataaaatca ttaaaaatca gcaaaagttg ttttattagt tagtttataa
    44761 tctattggtc ttcttcagtc cagtgtatct gctgtgacag ccactaaaag ttacaagtat
    44821 gattggaata cggttttgga atatagtacc aactatcacg accatcagta tgcttggatt
    44881 ccggaatggt ctcgttatta cagctattct gagtataaag ttggcggagg ctggaactac
    44941 gctcgttatg aggtcataaa ctactatact ggaggttatt aatccttaaa gagtgagaaa
    45001 aggagggctg gatatgttaa atcttactca tgttacctta aaaacgcgac aagtcatctt
    45061 gcaagatgcg gattttacct ttaaaaaggg taggatttat ggccttcttg ctatcaatgg
    45121 ctcgggaaag acgacactat tccgagctat gagcaagttg cttcccctta gtagtggaca
    45181 catcgcagtt cctccttctt tgttttatta tgagagcgtt gaatggctgg atggaaactt
    45241 aagtgggatg gactaccttc gtctcataaa aaacatctgg aagtcagacc taaacttgag
    45301 agatgaaatc gcctactggg aaatggctga ctatatcagt cttcccatcc gcaagtattc
    45361 cttagggatg aagcaacgct tggtgattgc tatgtatttt ctcagtcagg ccaaatgctg
    45421 gctcatggat gagattacaa atggcttaga cgagtattat cgacagaagt tttttgatag
    45481 gctagcacaa atcgatagac aagaacagct ggttctttta agttcccact ataaggaaga
    45541 gttggttgat atctgcgata gagtagtaac cattcatcag gggcagatag aagaggttta
    45601 gtttatgaaa gatgttagtc tatttttatt gaaaaaagtt ttcaaaagtc gtttaaactg
    45661 gattatctta cttttatttg catctgtact cggtgttacc ttttatttaa atagtcagac
    45721 tgcaaactca cacagcttgg agagcaggtt ggaaagtcgc attgcagcca acgagagggc
    45781 tatcaatgaa aatgaagaga aactctccca aatgtctgat accagctcgg aggaatacca
    45841 gtttgctaaa aataatttag acgtgcaaaa aaatcttttg acgcgaaaga cagaaattct
    45901 aactttacta aaagaagggc gctggaaaga agcctactat ctgcagtggc aagatgaaga
    45961 gaagaattat gaatttgtat caaatgaccc gactgctagc tctggcttaa aaatgggggt
    46021 tgaccgcgaa cggaagattt accaagccct gtatcccttg aacataaaag cacatacttt
    46081 ggagtttccg acccacggga ttgatcagat tgtctggatt ttagaggtta tcatcccaag
    46141 cttgtttgtg gttgcgatta tttttatgct aacacaacta tttgcagaaa gatatcaaaa
    46201 tcatctggac acagctcact tatatcctgt ttcaaaagtg acatttgcaa tatcctctct
    46261 tggagttgga gtgggatatg taactgtgct gtttatcgga atctgtggct tttcttttct
    46321 agtgggaagt ctgataagtg gttttggaca gttagattat ccctacccaa tttatagctt
    46381 agtgaatcaa gaagtaacta ttgggaaaat acaagatgta ttatttcctg gcttgctctt
    46441 agctttctta gcctttatcg tcattgtgga agttgtgtac ttgattgctt actttttcaa
    46501 gcaaaaaatg cctgtcctct ttctttcact cattgggatt gttggtttat tgtttggcat
    46561 ccaaaccatt cagcctcttc aaaggattgc acatctgatt ccctttactt acttgcgttc
    46621 agtggagatt ttatctggaa gattacctaa gcaaattgat aatgtcaatc taaattggag
    46681 catggggatg gtcttgcttc cttgcctgat tatccttttg ttagtgggga ttctatttat
    46741 cgaaagctgg ggaagttcac gtaaaaagga agtttttaaa gtttagtttt cctataggga
    46801 agctaaagaa aaactaacat agggagagaa tcaacttggt tctctctttt tgattcgaaa
    46861 accaaaccaa aatacaaaca caaacttttc aaaaaataac tttttatctt gacaagagct
    46921 agaaaacttg gtatcatata aaagttgaga aaagcagaag tgagagcttc tcgccttgtg
    46981 acattaagtt gcctggccct acggatgaaa agtttcgaag aaacgctatc ataacgtgcg
    47041 ggcttgtata tttacaagtc cgctattgtt tttctctaat aaaacaaaag aggtgaaaac
    47101 catagcaaag caagacttat tcatcaatga tgagattcgt gtacgtgaag ttcgcttgat
    47161 tggtcttgaa ggagaacagc taggtatcaa gccactcagt gaagcgcaag ctttggctga
    47221 taacgctaat gttgacctag tattgattca accccaagcc aaaccgcctg ttgcaaaaat
    47281 tatggactac ggtaagttca aatttgagta ccagaagaag caaaaagaac aacgtaaaaa
    47341 acaaagcgtt gttactgtga aagaagttcg tctaagtcca acaattgaca agggtgactt
    47401 tgatacaaaa cttcgtaatg cacgtaagtt ccttgaaaaa ggaaataaag ttaaggtatc
    47461 tattcgcttt aagggtcgta tgattaccca taaagagatt ggtgcaaaag ttttagccga
    47521 gtttgctgaa gcaactcaag atattgccat catcgaacaa cgtgctaaaa tggatggacg
    47581 tcaaatgttc atgcaattgg cgccagcgac tgacaaaaaa taattgtcag aaagttaaat
    47641 aaaggagaaa aaatcatgcc aaaacaaaaa acacaccgcg catcagctaa acgtttcaaa
    47701 cgtacaggtt ctggtggact taaacgtttc cgtgcttaca cttctcaccg tttccacgga
    47761 aaaactaaga aacaacgtcg tcatcttcgt aaagcatcta tggtgcattc aggagattac
    47821 aaacgtatca aagcaatgct tactcgcttg aaataatagc ttgactgtaa gtaaacaatt
    47881 ctaggaaata tttggaggaa ataaaacatg gcacgtgtta aaggtggcgt tgtatcacgc
    47941 aaacgtcgta aacgtattct taaattagca aaaggttact atggagctaa acacatcttg
    48001 ttccgtactg caaaagaaca agtaatgaac tcttactact atgcataccg tgaccgtcgt
    48061 cagaaaaaac gtgacttccg caaattgtgg attactcgta tcaatgcggc agctcgtatg
    48121 aacggacttt catactcaca attgatgcat ggtttgaaat tggctgagat tgaagttaac
    48181 cgtaaaatgc ttgctgactt ggctgttaac gatgcagtag ctttcacagc tcttgcagat
    48241 gcagctaaag caaaacttgg taaataataa ctgatgagac tggaacagga ttgtccagtc
    48301 tttttaaaaa taaaggagaa agatatggct tcaaaaatgc tacacacttg cttacgagta
    48361 gaaaatcttg aaaaatcaat cgcattttat caagatgctt ttggttttaa agaattgcgt
    48421 cgcagagatt ttccagacca tgccttcacg attgtctatc taggtcttga gggtgatgat
    48481 tatgagttgg agttgactta taactacgat cacggtccgt atgtggttgg tgatgggttt
    48541 gcccatatcg ccctcagtac acctgatctt gaggcacttc atcaagaaca cagtgcaaaa
    48601 ggctatgaag tgactgagcc aaatggtcta ccaggaacta caccaaacta ttactttgtt
    48661 aaagaccctg atggatataa ggtcgaagtc attcgtgaaa aataatttcg tgcaagttaa
    48721 gtagaatatt cgttttctac ttgacttttt ttagctgaaa gagtatacta ataaaaattc
    48781 aacctttaag gggagtccag agagactcac aaggtgtcag ataaaagaat agtgcaattt
    48841 tctagaggag accttttgag tgtgctctct tgtgttgtac gattttaact gaggccttgc
    48901 actagcaagg tcttttcttt atctggtccc cttaaaattt aaggaggaaa agttatgaat
    48961 ctcacatgta agaagcgttt gggtgtcatt cggttggaaa ccatgaaggt ggttgcacaa
    49021 gaggaaatcg cgccagcaat ctttgaatta gtcctagaag gagaaatggt tgaagccatg
    49081 cgagcaggcc aatttcttca tctgcgtgta ccagacgatg cccatctctt acgtcgtcct
    49141 atttcaattt cgtctattga caaggcaaac aagcagtgtc acctcattta tcggattgag
    49201 ggagctggga ctgcaatttt ttcaacctta agtcagggag acactcttga tgtgatgggg
    49261 cctcagggaa atggttttga cttgtctgac cttgatgagc agaatcaggt tctccttgtt
    49321 ggtggtggga ttggtgttcc acccttgctt gaggtggcca aggaattgca tgaacgtgga
    49381 gtgaaagtag tgacagtcct cggttttgct aataaggatg ctgttatttt gaaaacggaa
    49441 ttggctcagt atggtcaggt ctttgtaacg acagatgatg gttcttatgg catcaaggga
    49501 aatgtttccg ttgttatcaa tgatttagat agtcagtttg atgctgttta ctcgtgtggg
    49561 gctccaggaa tgatgaagta tatcaatcaa acctttgatg atcacccaag agcctattta
    49621 tctctggaat ctcgtatggc ttgtgggatg ggagcttgct atgcctgtgt tctaaaagta
    49681 ccagaaagcg agacggtcag ccaacgcgtc tgtgaagatg gtcctgtttt ccgcacagga
    49741 acagttgtat tataaggaga aaattatgac tacaaatcga ttacaagtgt ctctacctgg
    49801 tttggatttg aaaaatccga ttattccagc atcaggctgt tttggctttg gacaagagta
    49861 tgccaagtac tatgatttaa accttttagg ttctattatg atcaaggcga caacccttga
    49921 accacgtttt gggaacccaa ctccaagagt agcagagacg cctgctggta tgctcaatgc
    49981 aattggcttg caaaatcctg gtttagaggt tgttttggct gaaaagctac cttggctgga
    50041 aagagaatat ccaaatcttc ctattattgc caatgtagct ggtttttcaa aacaagagta
    50101 tgcagctgtt tctcatggga tttccaaggc aactaatgta aaagctatcg agctcaatat
    50161 ttcttgtccc aatgttgacc actgtaatca tggacttttg attggtcaag atccagattt
    50221 ggcttatgat gtggtgaaag cagctgtgga agcctcagaa gtgccagttt atgtcaaatt
    50281 aaccccgagt gtgaccgata tcgttactgt cgcaaaagct gcagaagatg cgggagcaag
    50341 tggcttgacc atgatcaata ctctggttgg aatgcgcttt gacctcaaaa ccagaaaacc
    50401 aatcttggcc aatggaacag gtggaatgtc aggtccagca gtctttccag tagccctcaa
    50461 actcatccgc caagtagccc aaacaacaga cctgcctatc attggaatgg ggggagtgga
    50521 ttcggctgaa gctgccctag aaatgtatct ggctggggca tctgctatcg gagttggaac
    50581 agctaacttt accaatcctt atgcctgccc tgacatcatc gaaaatttac caaaagtcat
    50641 ggataaatac ggtattagca gtctggaaga actccgtcag gaagtaaaag agtctctgag
    50701 gtaaactgca atcaatctgt tcttgatttt ttattagttt gtaatatgaa tttaggagaa
    50761 ttttggtaca ataaaataaa taagaacaga ggaagaaggt taatgaagaa agtaagattt
    50821 atttttttag ctctgctatt tttcttagct agtccagagg gtgcaatggc tagtgatggt
    50881 acttggcaag gaaaacagta tctgaaagaa gatggcagtc aagcagcgaa tgagtggatt
    50941 tttgatactc attatcaatc ttggttctat ataaaagcag atgctaacta tgctgaaaat
    51001 gaatggctaa agcaaggtga cgactatttt tacctcaaat ctggtggcta tatggccaaa
    51061 tcagaatggg tagaagacaa gggagccttt tattatcttg accaagatgg aaagatgaaa
    51121 agaaatgctt gggtaggaac ttcctatgtt ggtgcaacag gtgccaaagt aatagaagac
    51181 tggatctatg attctcaata cgatgcttgg ttttatatca aagcagatgg acagcacgca
    51241 gagaaagaat ggctccaaat taaagggaag gactattatt tcaaatccgg tggttatcta
    51301 ctgacaagtc agtggattaa tcaagcttat gtgaatgcta gtggtgccaa agtacagcaa
    51361 ggttggcttt ttgacaaaca ataccaatct tggttttaca tcaaagaaaa tggaaactat
    51421 gctgataaag aatggatttt cgagaatggt cactattatt atctaaaatc cggtggctac
    51481 atggcagcca atgaatggat ttgggataag gaatcttggt tttatctcaa atttgatggg
    51541 aaaatagctg aaaaagaatg ggtctacgat tctcatagtc aagcttggta ctacttcaaa
    51601 tccggtggct acatggcagc caatgaatgg atttgggata aggaatcttg gttttacctc
    51661 aagtttgatg gcaaaatggc tgaaaaagaa tgggtctacg attctcatag tcaagcctgg
    51721 tactacttca aatccggtgg ttacatgaca gccaatgaat ggatttggga taaggaatct
    51781 tggttttatc tcaaatctga tgagaaaata gctgaaaaag aatgggtcta cgattctcat
    51841 agtcaagctt ggtactactt caaatccggt ggttacatga cagccaatga atggatttgg
    51901 gataaggaat cttggtttta cctcaagtct gatggcaa
//
LOCUS       DAVAGB010000010        51683 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVAGB010000010 DAVAGB010000000
VERSION     DAVAGB010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51683
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.010"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            653..880
                     /locus_tag="VQO19_000647"
     CDS             653..880
                     /locus_tag="VQO19_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348942.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            1168..4065
                     /gene="nanA"
                     /locus_tag="VQO19_000648"
     CDS             1168..4065
                     /gene="nanA"
                     /locus_tag="VQO19_000648"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HET1348943.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPKGRVRLYVNGVLSRTSLRSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGNSNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPNRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLIFPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHKIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            5080..5532
                     /locus_tag="VQO19_000649"
     CDS             5080..5532
                     /locus_tag="VQO19_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET1348944.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            5551..6888
                     /locus_tag="VQO19_000650"
     CDS             5551..6888
                     /locus_tag="VQO19_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET1348945.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            6967..7851
                     /locus_tag="VQO19_000651"
     CDS             6967..7851
                     /locus_tag="VQO19_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET1348946.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            7851..8684
                     /locus_tag="VQO19_000652"
     CDS             7851..8684
                     /locus_tag="VQO19_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET1348947.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            8879..9982
                     /locus_tag="VQO19_000653"
     CDS             8879..9982
                     /locus_tag="VQO19_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET1348948.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            10156..10854
                     /locus_tag="VQO19_000654"
     CDS             10156..10854
                     /locus_tag="VQO19_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET1348949.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            10873..12390
                     /locus_tag="VQO19_000655"
                     /pseudo
     CDS             10873..12390
                     /locus_tag="VQO19_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
     gene            12515..13843
                     /locus_tag="VQO19_000656"
     CDS             12515..13843
                     /locus_tag="VQO19_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HET1348950.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            14095..14961
                     /locus_tag="VQO19_000657"
     CDS             14095..14961
                     /locus_tag="VQO19_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET1348951.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            14977..15816
                     /locus_tag="VQO19_000658"
     CDS             14977..15816
                     /locus_tag="VQO19_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET1348952.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            16088..16540
                     /locus_tag="VQO19_000659"
     CDS             16088..16540
                     /locus_tag="VQO19_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET1348953.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYDIDGD
                     KVFLVVQENVLNQAENDQFEYHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            16673..16981
                     /locus_tag="VQO19_000660"
     CDS             16673..16981
                     /locus_tag="VQO19_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348954.1"
                     /translation="MDGQGITVDEMAWIIRGIVNGLIGRYIKLGTYAAKYGISMARSI
                     LSRAAATAAARVGLSTKISGWILRVAVNVADVYGNFANNIAAAWDAHDKIPNNGRINF
                     "
     gene            16991..17290
                     /locus_tag="VQO19_000661"
     CDS             16991..17290
                     /locus_tag="VQO19_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348955.1"
                     /translation="MKALCIFLLNMLAWTVLAMIIRGGLDGFDEHTWSTILIASLFGV
                     YDYKPIDKNRKKSKRKKKKEKIDLFMVGTYESFTDKKENSLQRKMMEEQTWHKKE"
     gene            17272..17916
                     /locus_tag="VQO19_000662"
     CDS             17272..17916
                     /locus_tag="VQO19_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET1348956.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            18085..19002
                     /locus_tag="VQO19_000663"
     CDS             18085..19002
                     /locus_tag="VQO19_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET1348957.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            19020..19904
                     /locus_tag="VQO19_000664"
     CDS             19020..19904
                     /locus_tag="VQO19_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET1348958.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(19920..20771)
                     /locus_tag="VQO19_000665"
     CDS             complement(19920..20771)
                     /locus_tag="VQO19_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET1348959.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            20971..23028
                     /gene="pbp2b"
                     /locus_tag="VQO19_000666"
     CDS             20971..23028
                     /gene="pbp2b"
                     /locus_tag="VQO19_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HET1348960.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMAIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQPIVFQGSAPINSWYTQAYGSFPITAVEALEYSSN
                     AYMVQTALGIMGQTYQPNMFVLTNNLESAMGKLRSTFAEYGLGASTGIDLPDESTGFI
                     PKEYNFANYITNAFGQFDNYTPMQLAQYVGTIANNGVRIAPHIVEGIYGNNEQGGLGN
                     LIQSVESKEMNKINISESDVSILQQGFYQVSHGGSALTTGRAFSNGASVSISGKTGTA
                     ESYVEGGQEANNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYNQHH
                     PMN"
     gene            23039..23635
                     /gene="recR"
                     /locus_tag="VQO19_000667"
     CDS             23039..23635
                     /gene="recR"
                     /locus_tag="VQO19_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HET1348961.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSDDDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPVGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            23811..24854
                     /locus_tag="VQO19_000668"
     CDS             23811..24854
                     /locus_tag="VQO19_000668"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HET1348962.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVDYDRFTVKTFFISQ
                     SGDFIKTQEFSHDPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALELAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            24938..26311
                     /locus_tag="VQO19_000669"
     CDS             24938..26311
                     /locus_tag="VQO19_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HET1348963.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLAGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQVLDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQMILSLSPDVLDTVIFYGENIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGVHDQILLKGSNSMNLAKLVE
                     SLENETK"
     gene            26298..26909
                     /locus_tag="VQO19_000670"
     CDS             26298..26909
                     /locus_tag="VQO19_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET1348964.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQVSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIAALQFFAIDQLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            27000..27704
                     /locus_tag="VQO19_000671"
     CDS             27000..27704
                     /locus_tag="VQO19_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HET1348965.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            27923..29296
                     /gene="ftsA"
                     /locus_tag="VQO19_000672"
     CDS             27923..29296
                     /gene="ftsA"
                     /locus_tag="VQO19_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HET1348966.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVESVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            29313..30572
                     /gene="ftsZ"
                     /locus_tag="VQO19_000673"
     CDS             29313..30572
                     /gene="ftsZ"
                     /locus_tag="VQO19_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HET1348967.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVSPQARTATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            30577..31248
                     /locus_tag="VQO19_000674"
     CDS             30577..31248
                     /locus_tag="VQO19_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HET1348968.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDIIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            31258..31797
                     /locus_tag="VQO19_000675"
     CDS             31258..31797
                     /locus_tag="VQO19_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HET1348969.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            31797..32060
                     /locus_tag="VQO19_000676"
     CDS             31797..32060
                     /locus_tag="VQO19_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HET1348970.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            32057..32842
                     /locus_tag="VQO19_000677"
     CDS             32057..32842
                     /locus_tag="VQO19_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HET1348971.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEYL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            32851..33639
                     /gene="divIVA"
                     /locus_tag="VQO19_000678"
     CDS             32851..33639
                     /gene="divIVA"
                     /locus_tag="VQO19_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HET1348972.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPVPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVEAPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            33987..36779
                     /locus_tag="VQO19_000679"
     CDS             33987..36779
                     /locus_tag="VQO19_000679"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HET1348973.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
     gene            37181..37561
                     /locus_tag="VQO19_000680"
     CDS             37181..37561
                     /locus_tag="VQO19_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348974.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGPFVLLGTAVNTVATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDKRVGAAPSVLMIVFGGVSLIPFLGW
                     VGGILVIIGGSLFLATLKKFKSEE"
     gene            37755..38045
                     /locus_tag="VQO19_000681"
     CDS             37755..38045
                     /locus_tag="VQO19_000681"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348975.1"
                     /translation="MIESIRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKL
                     KESTQKLFDAQKKRLNNEDRIETAKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            38096..38788
                     /locus_tag="VQO19_000682"
     CDS             38096..38788
                     /locus_tag="VQO19_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HET1348976.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            38841..41252
                     /locus_tag="VQO19_000683"
     CDS             38841..41252
                     /locus_tag="VQO19_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET1348977.1"
                     /translation="MIRNKKQDYVLAYKQPVSTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     RKAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYETYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TDVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGNGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            41463..42164
                     /locus_tag="VQO19_000684"
     CDS             41463..42164
                     /locus_tag="VQO19_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1348978.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLFGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIQMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            42166..44874
                     /locus_tag="VQO19_000685"
     CDS             42166..44874
                     /locus_tag="VQO19_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET1348979.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEDHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAS
                     IVTFTTMTRFVDEERTHAGIFKALGYRSKDIITKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATDQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNVSAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPSTI
                     LFYPQVGWEVYVIPVVAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(44970..45461)
                     /gene="tpx"
                     /locus_tag="VQO19_000686"
     CDS             complement(44970..45461)
                     /gene="tpx"
                     /locus_tag="VQO19_000686"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HET1348980.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGHDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(45584..46513)
                     /gene="psaA"
                     /locus_tag="VQO19_000687"
     CDS             complement(45584..46513)
                     /gene="psaA"
                     /locus_tag="VQO19_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HET1348981.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(46545..47393)
                     /locus_tag="VQO19_000688"
     CDS             complement(46545..47393)
                     /locus_tag="VQO19_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET1348982.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(47390..48112)
                     /locus_tag="VQO19_000689"
     CDS             complement(47390..48112)
                     /locus_tag="VQO19_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET1348983.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            48403..50295
                     /gene="pepO"
                     /locus_tag="VQO19_000690"
     CDS             48403..50295
                     /gene="pepO"
                     /locus_tag="VQO19_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HET1348984.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(50418..51047)
                     /locus_tag="VQO19_000691"
     CDS             complement(50418..51047)
                     /locus_tag="VQO19_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET1348985.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
BASE COUNT        15770 a         9321 c        11385 g        15207 t
ORIGIN      
        1 tgtatttata gaattttttg ttgctagatt tgtcaaattg cttaaaataa tttttttcag
       61 aaagcaaaag ccgataccta tcgagtaggg tagttcttgc tatcgttagg cttgtctgta
      121 ggtgttaata cttttcaaaa atctcttcaa accacgtcag cttcgccttg ccgtatatat
      181 gttactgact tcgtcagttc tatctgccac ctcaaaacgg tgttttgagc tgacttcgtc
      241 agttctatct gccacctcaa aacggtgttt tgagctgact ttgtcagtct tatctacaac
      301 ctcaaaacag tgttttgagc atcatgcggc tagcttctta gtttgctctt tgatttttat
      361 tgagtataaa aacagatgag tttctgtttt ctttttatgg actataaatg ttcagctgaa
      421 actactttca aggacattat tatataaaag atttttttga aactaaaatc tactatatta
      481 cactatattg aaagcgtttt aaaaataagg tataataaat ttactaacac ttataaaaag
      541 tgatagaatc tatctttatg tatatttaaa gatagattgc tgtaaaaata gtagtagcta
      601 tgcgaaataa cagatagaga gaagggattg aagcttagaa aaggggaata atatgatatt
      661 taaggcattc aagacaaaaa agcagagaaa aagacaagtt gaactacttt tgacagtttt
      721 tttcgacagt tttctgattg atttatttct tcacttattt gggattgtcc cctttaagct
      781 ggataagatt ctgattgtga gcttgattat atttcccatt atttctacaa gtatttatgc
      841 ttatgaaaag ctatttgaaa aagtgttcga taaggattga gcaggaagta tggtgtaaat
      901 agcataggct gatgtccatc atttgcttat aaagagatat tttagtttaa ttgcagcggt
      961 gtcctggtag ataaactaga ttggcaggag tctgattgga gaaaggagag gggaaatttg
     1021 gcaccaattt gagatagttt gtttagttca tttttgtcat ttaaatgaac tgtagtaaaa
     1081 gaaagttaat aaaagacaaa ctaagtgcat tttctggagt aaatgtctta tttcagaaat
     1141 cgggatatag atatagagag gatcagtatg aatcggagtg ttcaagaacg taagtgtcgt
     1201 tatagcatta ggaaactatc ggtaggagcg gtttctatga ttgtaggagc agtggtattt
     1261 ggaacgtctc ctgttttagc tcaagaaggg gcaagtgagc aacctctggc aaatgaaact
     1321 caactttcgg gggagagctc aaccctaact gatacagaaa agagccagcc ttcttcagag
     1381 actgaacttt ctggcaataa gcaagaacaa gaaaggaaag ataagcaaga agaaaaaatt
     1441 ccaagagatt actatgcacg agatttggaa aatgtcgaaa cagtgataga aaaagaagat
     1501 gttgaaacca atgcttcaaa tggtcagaga gttgatttat caagtgaact agataaacta
     1561 aagaaacttg aaaacgcaac agttcacatg gagtttaagc cagatgccaa ggccccagca
     1621 ttctataatc tcttttctgt gtcaagtgct actaaaaaag atgagtactt cactatggca
     1681 gtttacaata atactgctac tctagagggg cgtggttcgg atgggaaaca gttttacaat
     1741 aattacaacg atgcaccctt aaaagttaaa ccaggtcagt ggaattctgt gactttcaca
     1801 gttgaaaaac cgacagcaga actacctaaa ggccgagtgc gcctctacgt aaacggggta
     1861 ttatctcgaa caagtctgag atctggcaat ttcattaaag atatgccaga tgtaacgcat
     1921 gtgcaaatcg gagcaaccaa gcgtgccaac aatacggttt gggggtcaaa tctacagatt
     1981 cggaatctca ctgtgtataa tcgtgcttta acaccagaag aggtacaaaa acgtagtcaa
     2041 ctttttaaac gctcagattt agaaaaaaaa ctacctgaag gagcggcttt aacagagaaa
     2101 acggacatat tcgaaagcgg gcgtaacggt aactcaaata aagatggaat caagagttat
     2161 cgtattccag cacttctcaa gacagataaa ggaactttga tcgcaggtgc agatgaacgc
     2221 cgtctccatt cgagtgactg gggtgatatc ggtatggtca tcagacgtag tgaagataat
     2281 ggtaaaactt ggggtgaccg agtaaccatt accaacttac gtgacaatcc aaaagcttct
     2341 gacccatcga tcggttcacc agtgaatatc gatatggtgt tggttcaaga tcctgaaacc
     2401 aaacgaatct tttctatcta tgacatgttc ccagaaggga agggaatctt tggaatgtct
     2461 tcacaaaaag aagaagccta caaaaaaatc gatggaaaaa cctatcaaat cctctaccgt
     2521 gaaggagaaa agggagctta taccattcga gaaaatggta ctgtctatac accagatggt
     2581 aaggcgacag actatcgcgt tgttgtagat cctgttaaac cagcctatag cgacaagggt
     2641 gatctataca agggtaacca attactaggc aatatctact tcacaacaaa caaaacttct
     2701 ccatttagaa ttgccaagga tagctatcta tggatgtcct acagtgatga cgacgggaag
     2761 acatggtcag cgcctcaaga tattactccg atggtcaaag ccgattggat gaaattcttg
     2821 ggtgtaggtc ctggaacagg aattgtactt cggaatgggc ctcacaaggg acggattttg
     2881 ataccagttt atacgactaa taatgtatct cacttaaatg gctcgcaatc ttctcgtgtc
     2941 atctattcag atgatcatgg aaaaacttgg catgctggag aagcggtcaa cgataaccgt
     3001 caggtagacg gtcaaaagat ccactcttct acgatgaaca atagacgtgc gcaaaataca
     3061 gaatcaacgg tggtacaact aaacaatgga gatgttaaac tctttatgcg tggtttgact
     3121 ggagatcttc aggttgctac aagtaaagac ggaggagtga cttgggagaa ggatatcaaa
     3181 cgttatccac aggttaaaga tgtctatgtt caaatgtctg ctatccatac gatgcataat
     3241 ggaaaagaat acattatcct cagcaatgca ggtggaccga atcgtgaaaa tgggatggtc
     3301 cacttggcac gtgtcgaaga aaatggtgag ttgacttggc tcaaacacaa tccaattcaa
     3361 aaaggagagt ttgcctataa ttcgctccaa gaattaggaa atggggagta tggcatcttg
     3421 tatgaacata ctgaaaaagg acaaaatgcc tataccctat catttagaaa atttaattgg
     3481 gactttttga gcaaagatct gatttttcct accgaagcga aagtgaagcg aactagagag
     3541 atgggcaaag gagagatggg caaaggagtt attggcttgg agttcgactc agaagtattg
     3601 gtcaacaagg ctccaaccct tcaattggca aatggtaaaa cagcgacttt cctaacccag
     3661 tatgatagca agaccttgtt gtttgcagta gataaggaag atatcggaca ggaaattatt
     3721 ggtatagcta aaggaagcat cgaaagtatg cataatcttc ctgtaaatct agcaggtgcc
     3781 agagttcctg gcggagtaaa tggtagcaaa gcagcggtgc atgaagttcc agaatttaca
     3841 gggggagtta atggtacaga gccagctgtt cataaaatcg cagagtataa gggatctgat
     3901 tcgcttgtaa ctcttactac aaaagaagat tatacttaca aagctcctct tgctcagcag
     3961 gcacttcctg aaacaggaaa caaggagagt gacctcctag cttcactagg actaacagct
     4021 ttcttccttg gtctgtttac gctagggaaa aagagagaac aataagagaa gaattctaaa
     4081 catttgattt tgtaaaaata gaaggagata gcaggttttc aagcctgcta tctttttttg
     4141 atgacattca agctgatacg aaatcataag aggtctgaaa ctactttcag agtagtctgt
     4201 tctataaaat atagtagatt gaaataagat gtgaacaact ctatcaggaa agtcaaatta
     4261 atttatagaa aaattttagc agtcaaggtg tactgttata gattcaatat attatgcgac
     4321 cattaacctt gtcttctcct aaaattgact ttcttgtttt cttatcttgt ccactcgaaa
     4381 caagtattgt aagaatttga ttatttttga aagtactttt aatatacttg atatagttaa
     4441 aaaagatttg aaactaaatt ccaaattaga aaaagacttg aaatactaaa aaaaaaaagt
     4501 atactctaat tgaaaacggt aacaaaacta atttagagaa tgaaatatag agtatttctc
     4561 tcttaaaagt ttttggtgaa acgagatgta gaaaggagat ttagccaaag agtctattag
     4621 tgctagaata atagattaga attattttag aaaaacgaag tgagcagctt ataaattcaa
     4681 gtccccaaat agattcatac tagtatcttt tgcaaaaaat aaagggcgac ttccttcatg
     4741 aatatcaatt tcatctataa ggaaggtagc taattgaact aacttattta ttctgtttgt
     4801 cgctagaaaa atcagacctc cttgtgaaga ttgaggagat actgaatgaa aatcaaagaa
     4861 gaaactagca agctagtagc agattgccca aaacaccgct ttgaggttgt agataagact
     4921 gacctatata atccaaggtg aagcgactgt ggtttgaaga gattttcaaa gagtataggc
     4981 tagagagtag tgtttttatg tccttctagt agaaaatgct agacagaaga atggggaact
     5041 tggataggag aaatagattg agaaaggagg ttagaagaga tgattattac aaaaattagc
     5101 cgtttaggaa cttatgtggg agtaaatcca cattttgcaa cattaataga ttttctagaa
     5161 aaaacaggac tagaaaattt aacagaaggt tcgattgcta tcgatggtaa tcgattgttt
     5221 gggaattgct ttacttatct agcagatggt caagcagggg ctttctttga aacacaccaa
     5281 aaatatttgg atattcattt agttttggaa aacgaagaag ccatggctgt tacatcgccg
     5341 gaaaatgtaa gcgttaccca agaatatgat gaagagaaag atattgaatt atacacaggg
     5401 aaagtggaac agttggttca tttgagagct ggtgaatgcc tcatcacttt tccagaagat
     5461 ttacatcaac ccaaggttcg tataaatgat gaacctgtga aaaaagttgt ctttaaagtt
     5521 gcgatttctt aatgtagaaa gagaagaacg atgaaaaaaa tgagaaagtt tttatgtcta
     5581 gctggaattg cgctagcggc tgttgccttg gtagcttgtt caggaaaaaa agaagctaca
     5641 actagtactg aaccaccaac agaattatct ggtgagatta caatgtggca ctcctttact
     5701 caaggacccc gtttagaaag tattcaaaaa tcagcagatg ctttcatgca aaagcatcca
     5761 aaaacgaaaa tcaagattga aacattttct tggaatgact tctatactaa atggactaca
     5821 ggtttagcaa atggaaatgt gccagatatc agtacagctc ttcctaacca agtaatggaa
     5881 atggtcaact cagatgcttt ggttccgcta aatgattcta tcaagcgtat tggacaagat
     5941 aaatttaacg aaactgcctt aaatgaagca aaaatcggag atgattacta ctctgttcct
     6001 ctttattcac atgcacaagt catgtgggtt agaacagatt tgttaaaaga acataatatt
     6061 gaggttccta aaacttggga tcaactctat gaagcttcta aaaaattgaa agaagctgga
     6121 gtttatggct tgtctgttcc gtttggaaca aatgacttaa tggcaacacg tttcttgaac
     6181 ttctacgtac gtagtggtgg aggaagcctc ttaacaaaag atcttaaagc agacttgaca
     6241 agccaacttg ctcaagatgg tattaaatac tgggttaaat tgtataaaga aatctcacct
     6301 caagattctt tgaattttaa tgtccttcaa caagctacct tgttctatca aggaaaaaca
     6361 gcatttgact ttaactctgg cttccatatc ggaggaatta atgccaacag tcctcaattg
     6421 attgattcga ttgatgctta tcctattcca aaaatcaaag agtctgataa agaccaagga
     6481 attgaaacct caaacattcc aatggttgtt tggaaaaatt caaaacatcc agaagttgct
     6541 aaagcattct tagaagcact ttataatgaa gaagactacg ttaaattcct tgattcaact
     6601 ccagtaggta tgttgccaac tattaagggg attagcgatt ctgcagccta taaagaaaat
     6661 gaaactcgta agaagtttaa acatgctgaa gaagtaatta ctgaagctgt taaaaaaggt
     6721 actgctattg gttatgaaaa tggaccaagt gtacaagctg gtatgttgac taaccaacac
     6781 attattgaac aaatgttcca agatatcatt acaaatggaa cagatcctat gaaagcagca
     6841 aaagaagcag aaaaacaatt aaacgattta tttgaggctg ttcagtagat gtaaaagact
     6901 agaaaatagg tgggctagtg atctgaaaag ctctagccca attttgtaaa agaagggaga
     6961 aggagaatgg ttaaagaacg taatttaact cgctggatat ttgttttgcc agctatgatt
     7021 atcgtaggat tactctttgt ttatccgttt ttctcgagta ttttttatag ctttaccaat
     7081 aagcatttga ttatgcctaa ttataaattt gttggtttgg ctaactataa agctgtgcta
     7141 tcagatccca acttctttaa tgcgttcttt aattcaatta agtggaccgt tttctcatta
     7201 gttggtcaag ttttagtagg gtttgtgttg gctttagctc ttcacagagt acgccacttc
     7261 aagaaattat ataggacctt attgattgtt ccttgggcat ttcctaccat cgttattgcc
     7321 ttctcttggc agtggattct aaacggggtt tatggctact tacctaatct aatcgtaaaa
     7381 ttaggtttaa tggaacatac acctgcattt ttgacagata gtacatgggc attcctatgt
     7441 ttggtgttta tcaacatttg gtttggagca ccaatgatta tggttaatgt gctttcagct
     7501 ttgcaaacag taccagaaga acaatttgag gctgctaaga tagatggtgc ttcaagttgg
     7561 caggtgttca agtttatcgt ctttccacat attaaagtgg ttgtaggact tctagttgtt
     7621 ttgagaactg tatggatctt taataacttt gacattatct acctcattac tggtggtgga
     7681 ccagccaatg ctacaacgac gcttccaatt tttgcttaca acctgggctg gggaactaaa
     7741 ttgttgggtc gtgcttcagc agttacagta ttgctcttta tcttcttggt ggcgatttgc
     7801 tttatctact ttgctatcat cagtaagtgg gaaaaggagg gtagaaaata atgaagaaga
     7861 aatccagtat ttatttagat attctctcac atgtactttt agttggtgcg accatcgttg
     7921 caattttccc attggtatgg attatcatat cttctgtcaa agggaaaggg gaattaactc
     7981 agtatccaac acgattttgg cctgaacagt ttacattaga ttatttcact catgttatca
     8041 acgatttgca cttcattgat aacattcgaa acagtttaat cattgccttg gctacaaccc
     8101 tcattgcgat tattatttct gctatggcag cctatggtat tgttcgattc tttcctaaat
     8161 tgggagcaat catgtcgaga ctactcgtca ttacctacat tttcccacca attttgttag
     8221 caattcccta ttcaattgcc attgctaaag ttgggttaac aaatagttta tttggcttga
     8281 tgatggttta tctatctttt agtgttccat atgcagtttg gctcttagtt ggatttttcc
     8341 aaacagttcc aattggaatt gaagaagcgg ctagaattga tggtgcaaat aaatttgtta
     8401 cgttttataa agttgtgcta ccgattgtag caccaggtat tgtagcaaca gctatttata
     8461 catttatcaa tgcttggaat gaattcctgt atgccttgat tttgattaac aatacaggaa
     8521 agatgacagt agcagtagcc cttcgttcac ttaatggttc agaaatacta gactggggag
     8581 atatgatggc agcgtctgtt attgtagttc ttccatcaat tattttcttc tctatcatcc
     8641 aaaataagat tgcaagtgga ttatcagaag gatctgtgaa gtaatactca atgaaaatca
     8701 aagagcaaac taggaaacta gccgcaggct gctcaaagta cagctttgag gttgcagata
     8761 aaactgacga agtcagtaac catacgcaca gtaaggcgac gttgacgcgg tttgaagaga
     8821 ttttcgaaga gtataagtta aaattagaaa gtttattcaa taataaagga gaaaaaacat
     8881 ggttaaatac ggtgttgttg gagcagggta ttttggagct gaattggctc gctacatgca
     8941 aaagaatgat ggagcagaga ttactcttct ctatgatcca gataatgcag aggcgattgc
     9001 agaagaattg ggagcaaaag tagcaagttc cttagatgag ttggtttcta gcgatgaagt
     9061 agattgtgtt atcgtcgcaa ctccaaataa tcttcataag gaaccggtta ttaaggctgc
     9121 acagcatggt aaaaatgttt tctgtgaaaa accaattgcg ctttcttatc aagattgtcg
     9181 cgagatggta gatgcgtgta aagaaaacaa tgtaaccttt atggcaggac atattatgaa
     9241 tttctttaat ggtgttcatc atgcaaaaga actcattaat caaggagtta tcggagacgt
     9301 tctatattgt catacagctc gtaatggttg ggaagaacaa caaccgtcag tatcatggaa
     9361 aaaaattcgt gaaaaatcag gtggtcactt gtatcaccac atccatgaat tggattgcgt
     9421 tcaattcctt atggggggca tgcctgaaac tgtaaccatg acaggtggaa atgtggccca
     9481 tgaaggtgaa catttcggtg atgaagatga tatgattttt gtcaatatgg aattttctaa
     9541 taagcgtttt gctttgttag aatggggttc agcttatcgt tggggtgaac attatgtctt
     9601 aatccaagga agcaaaggtg ccatccgctt agacttattc aactgtaaag gaactcttaa
     9661 gctagatggg caagaaagct atttcttgat tcacgaatcg caagaagaag atgatgatcg
     9721 gactcgtatc tatcatagta cagagatgga tggagcaatt gcttatggta aaccaggtaa
     9781 acgtactcca ttatggctat catctgtcat tgataaagaa atgcgctatc tgcatgagat
     9841 tatggaagga gctccagtat cagaagaatt tgcaaaactt ttgacaggtg aagctgccct
     9901 agaagcaatt gctactgcag atgcttgtac ccagtctatg tttgaagatc gcaaagtaaa
     9961 attgtcagaa attgtaaaat aaattttggt attctcctat ttataggtcg acttgctcct
    10021 ctgaaagtac ttttagagga gctgtttgac tttgctagtt tttgaaactg aaatctatta
    10081 tactacaaac tattgaaagc gttttaattt taaggtataa taatctcata gaaataaaga
    10141 aaaggaggaa agaggatgcc acagattagc aaagaagcct tgattgagca aatcaaagat
    10201 ggaatcatcg tttcttgtca ggctcttcct catgaaccgc tttatacaga agcgggaggg
    10261 gtgattccct tgctggtcaa agcggctgag caaggtggag cagtcggtat ccgagcaaac
    10321 agtgttcgcg atatcaagga aattaaggaa gtcactaaac ttccaatcat tgggattatc
    10381 aaacgtgatt atccacctca ggaacccttc atcacggcta ctatgaaaga agttgatgaa
    10441 ttggcagaac tggacatcga ggtgattgct ctggattgta ccaagcgtga acgctacgat
    10501 ggtttggaaa ttcaagagtt cattcgtcag gttaaggaga aatatcctaa tcagcttttg
    10561 atggctgata ctagtatctt cgaagaaggg ctagcagctg tagaagcagg aattgacttt
    10621 gtcggaacaa ccttatcagg ctacacatcc tacagtccaa aagtagacgg tccagatttt
    10681 gaattgatta agaaactctg tgatgccggt gtagatgtca ttgcagaagg aaaaattcat
    10741 acaccagaac aagccaaaca aatccttgaa tatggagtgc gaggcatcgt tgttggtggc
    10801 gccattacta gaccaaaaga gattacagaa cgcttcgttg ctagtcttaa ataagatgtg
    10861 agggggagtt ttatgtttaa agttttacaa aaagttggaa aagcttttat gttacctata
    10921 gctatacttc ctgcagcagg tctacttttg gggattggtg gtgcactttc aaacccaacc
    10981 acgatagcaa cttatccaat actagacaat agtatttttc aatcaatatt ccaagtaatg
    11041 agctctgcag gagaggttgt attcagtaat ttgtcactac ttctctgtgt gggattatgt
    11101 attggcttag cgaaacgaga taaaggaacc gctgcgttag caggagtaac tggttactta
    11161 gttatgactg caacgatcaa agctttggta aaacttttta tggcagaagg atctgcaatt
    11221 gatactggag ttattggagc attagttgtc ggaatagttg ccgtatattt gcacaaccga
    11281 tataacaata ttcaattacc ttccgcttta ggattctttg gaggttcacg cttcgttcct
    11341 attgttacat cgttctcttc tatcttgatt ggctttgtct tctttgttat ttggccacct
    11401 ttccaacaac ttcttgtttc tacaggtgga tatatttctc aggcgggtcc aattggaact
    11461 tttctatatg gatttttaat gagactttct ggagcagtag gcttacatca tataatttac
    11521 cctatgtttt ggtatactga acttggtggt gttgaaactg ttgcaggaca aacagtggtt
    11581 ggagctcaaa aaatattttt tgctcaatta gccgatccgg cccattctgg attatttaca
    11641 gaaggaacaa ggttttttgc aggtcgtttc tcaacaatga tgttcggttt accggctgcc
    11701 tgtttagcga tgtaccatag tgttcctaaa aatcgtcgta aaaaatacgc gggtttgttt
    11761 ttttgagttg ctttaacatc ttttattacc ggtattacag aaccaattga atttatgttt
    11821 ctattcgtca gtccggttct atatgttgtt cacgcattcc ttgatggtgt tagcttcttt
    11881 attgcagacg tcttaaatat ttcaatagga aacacatttt caggaggtgt aatcgatttc
    11941 actttatttg gaattttgca ggggaacgct aagacgaatt gggttcttca gattccaatt
    12001 ggacttattt ggagtgtttt gtattatatt atttttagat ggttcattac tcaattcaac
    12061 gttctaacgc caggacgagg agaagaagta gattctaaag aaatttctga atccgcagat
    12121 tcaacttcaa atactgcaga ttatttaaaa caggatagcc tacaaattat cagagccttg
    12181 ggtggatcaa ataatataga agatgtagat gcttgtgtga cacgtttacg tgtagctgta
    12241 aaagaagtta atcaagttga taaagcactt ttaaaacaaa ttggtgcagt tgatgtctta
    12301 gaagtgaagg gtggcattca agcaatctat ggagcaaaag caatcttata taaaaatagt
    12361 attaatgaaa ttttaggtgt agatgattaa gtacttactg acttaataaa aaacagagga
    12421 gagtgatgga tgagtaggat gaaatgaaat cgcatacaag aaataaagaa ctcattatcc
    12481 aagttggata cgcttattac ataggagaat acaaatgaaa tttagaaaat tagcttgtac
    12541 agtacttgcg ggtgctgcgg ttcttggtct tgctgcttgt ggcaattctg gcggaagtaa
    12601 agatgctgcc aaatcaggtg gtgacggtgc caaaacagaa atcacttggt gggcattccc
    12661 agtatttacc caagaaaaaa ctggtgacgg tgttggaact tatgaaaaat caatcatcga
    12721 agcgtttgaa aaagcaaacc cagatataaa agtgaaattg gaaaccatcg acttcaagtc
    12781 aggtcctgaa aaaatcacaa cagccatcga agcaggaaca gctccagacg tactctttga
    12841 tgcaccagga cgtatcatcc aatacggtaa aaacggtaaa ttggctgagt tgaatgacct
    12901 cttcacagat gaatttgtta aagatgtcaa caatgaaaac atcgtacaag caagtaaagc
    12961 tggagacaag gcttatatgt atccgattag ttctgcccca ttctacatgg caatgaacaa
    13021 gaaaatgtta gaagatgctg gagtagcaaa ccttgtaaaa gaaggttgga caactgatga
    13081 ttttgaaaaa gtattgaaag cacttaaaga caagggttac acaccaggtt cattgttcag
    13141 ttctggtcaa gggggagacc aaggaacacg tgcctttatc tctaaccttt atagcggttc
    13201 tgtaacagat gaaaaagtta gcaaatatac aactgatgat cctaaattcg tcaaaggtct
    13261 tgaaaaagca actagctgga ttaaagacaa tttgatcaat aatggttcac aatttgacgg
    13321 tggggcagat atccaaaact ttgccaatgg tcaaacatct tacacaatcc tttgggcacc
    13381 agctcaaaat ggtatccaag ctaaactttt agaagcaagt aaggtagaag tggtagaagt
    13441 accattccca tcagacgaag gtaagccagc tcttgaatac cttgtaaacg ggtttgcagt
    13501 attcaacaat aaagacgaca agaaagtcgc tgcatctaag aaattcatcc agtttatcgc
    13561 agatgacaag gagtggggac ctaaagacgt agttcgtaca ggtgctttcc cagtccgtac
    13621 ttcatttgga aaactttatg aagacaaacg catggaaaca ataagcggct ggactcaata
    13681 ctactcacca tactacaaca ctattgatgg atttgctgaa atgagaacac tttggttccc
    13741 aatgttgcaa tctgtatcaa atggtgacga aaaaccagca gatgctttga aagccttcac
    13801 tgaaaaagcg aacgaaacaa tcaaaaaagc tatgaaacaa tagtccttag ttattctata
    13861 aaaagtagtt ttttaaagaa cctaagagtg tataccccct tttccctcta cacagatagt
    13921 gtaagaaaag ggggcttttg tttaaaatgt aagaaactgt cacgaaatta aaatgaagtt
    13981 cttacataag cgaatcataa aaaatttcat tttgatttta aaacagttca agaaagtcaa
    14041 aaaattattc tatttgaaag agaggtgccg actgtgaaag tcaataaaat ccgtatgcgg
    14101 gaaacagtga tttcctacgc tttcctagca ccagtattat tcttctttgt catctttgtg
    14161 ttggctccga tggtgatggg cttcattaca agtttcttta actactcaat gactaaattt
    14221 gagtttgtag gcttggataa ctatatccgt atgtttaaag atcctgtctt tacaaaatct
    14281 ctgattaaca cagttatttt ggttattgga tctgtaccag ttgttgttct attctcactc
    14341 tttgtagcat ctcagaccta tcatcaaaat gtcattgcca gatccttcta ccgtttcgtc
    14401 ttcttccttc ctgttgtaac gggtagtgtt gccgtgacag ttgtttggaa atggatttat
    14461 gacccactat cagggattct aaactttgtc cttaagtcca gccacatcat cagccaaaac
    14521 atttcttggt tgggagataa aaactgggca ttgatggcga ttatgattat tctcttgacc
    14581 acttcagttg gtcagcccat catcctttat atcgctgcca tggggaatat tgacaattca
    14641 ctggttgaag cggcgcgtgt tgatggtgca actgagtttc aagttttttg gaagattaaa
    14701 tggccaagcc ttcttccaac aactctttat attgcaatca tcacaacaat taactcattc
    14761 cagtgttttg ccttgattca gcttttgaca tctggtggtc caaactactc aacaagtacc
    14821 ttgatgtact acctttacga aaaagccttc caattgacag aatacggcta tgccaacaca
    14881 attggtgtct tcttggcagt catgattgct atcgtaagct ttgttcaatt taaagtactt
    14941 ggaaacgacg tagaatacta aagaaaggag acagctatgc aatctacaga aaaaaaacca
    15001 ttaacagcct ttactgttat ttcaacaatc attttgctct tgttgactgt gctgttcatc
    15061 tttccattct actggatttt gacaggggca ttcaaatcac aacctgatac aattgttatt
    15121 cctcctcagt ggttccctaa aatgccaacc atggaaaact tccaacaact catggtgcag
    15181 aaccctgcct tgcaatggat gtggaactca gtatttatct cattggtaac catgttctta
    15241 gtttgtgcaa cctcatctct agcaggttat gtattggcta aaaaacgttt ctatggtcaa
    15301 cgcattctat ttgctatctt tatcgctgct atggcgcttc caaaacaagt tgtccttgta
    15361 ccattggtac gtatcgtcaa cttcatggga atccacgata ctctctgggc agttatcttg
    15421 cctttgattg gatggccatt cggtgtcttc ctcatgaaac aatttagtga aaatattcct
    15481 acagagttgc ttgaatcagc taaaatcgac ggttgtggtg agattcgtac cttctggagt
    15541 gtagccttcc cgattgtgaa accagggttt gcagcccttg caatctttac cttcatcaat
    15601 acttggaatg actacttcat gcaattggta atgttgactt cacgtaacaa tttgaccatc
    15661 tcacttgggg ttgcgaccat gcaggctgaa atggcaacca actatggttt gattatggca
    15721 ggagctgccc ttgctgctgt tccaatcgtc acagtcttcc tagtcttcca aaaatccttc
    15781 acacagggta ttactatggg agcggtcaaa ggataatact ctgagaaaat ctcttcaaac
    15841 tacgtcagcg tcaccttgcc atacttaagt attgcctgcg gttagcttcc tagtttgttc
    15901 ttcaattttc attgagtata ggaaaatcaa tctatcaaga tacagaagta tattttatag
    15961 atttagagaa tatagaggtt ataagtgtct acaaaatgga gggtatgcag ttactttatg
    16021 aagttttgtc agacacttat aaacttaaga atggttttag ttaactatca gaaacgaagg
    16081 aaagagtatg atttttgacg atttgaaaaa catcaccttt tacaaaggga ttcatcctaa
    16141 tttagacaag gctatcgact atctctacca acatcgtaag gattctttcg aattaggaaa
    16201 gtatgatatt gatggagata aagtctttct agttgttcag gaaaatgtcc tcaatcaagc
    16261 tgaaaatgat caatttgagt atcataagaa ctatgcagat ttgcatttgc tggtagaagg
    16321 acatgaatat tcgagctacg gttcacgtat caaagacgag gcagtagcat tcgacgaagc
    16381 gagtgacatt ggctttgttc attgtcatga acactaccca ctcttgttgg gttatcacaa
    16441 ttttgcgatt ttcttcccag gtgagccaca tcagccaaat ggttatgcag gcatggaaga
    16501 aaaggttcgg aaatatctct ttaaaatttt gattgattaa aaataggatg aattgttttt
    16561 ttgtaaagct ttgacaatac tctaccatga aattgatctt tgtgaggtag ggaaatgaga
    16621 ataaaatatt taaaaattgg tatcttctaa gtatgctgca agagctagtt tcttggatgg
    16681 acagggaatt acagttgatg agatggcttg gataattagg ggcattgtga atggattgat
    16741 tggtagatac ataaaattag gtacttatgc agccaagtat ggtattagta tggcgcgttc
    16801 gatcttaagt agggcagctg caactgcagc agcaagagta ggattatcga ccaagatttc
    16861 tggatggatt ttacgagtag ctgtgaatgt agctgatgta tatggtaatt ttgccaacaa
    16921 tattgctgca gcttgggatg cacatgataa aattcctaac aatggtcgta taaactttta
    16981 aaatgcgaga atgaaagcac tttgtatttt tttattgaat atgttagctt ggacagtgct
    17041 tgcaatgata attcgtggag ggctagatgg atttgatgag catacttgga gtactatttt
    17101 aattgcttcg ctgttcgggg tatatgatta taagcccata gataaaaata gaaaaaagtc
    17161 caaaagaaaa aagaaaaaag aaaaaataga tttgttcatg gtagggactt atgaaagctt
    17221 tactgacaaa aaagaaaaca gtttacaaag aaaaatgatg gaggagcaaa catggcacaa
    17281 aaaggagtaa gccttatcaa ggcagcattt gatacagaca actttctcat gcgttttagt
    17341 gagaaagtct tggacatcgt gacagccaat cttctttttg tcgtctcttg tttgcccatc
    17401 gtgacgattg gagtggctaa aatcagcctc tacgagacca tgttcgaagt taagaagagc
    17461 agacgggtgc ctgtttttaa aatctatcta agatctttca agcaaaatct gaaactaggt
    17521 cttcagctgg gtttaatgga gttaggaatt gtgtttctta ccctttcaga tctctatctt
    17581 ttctggggtc aaacagctct gcccttccaa ttgctgaaag ccatttgttt aggtattctg
    17641 atttttctta ctatcgtgat gctggctagt taccctatcg cggcacgtta tgacctatct
    17701 tggaaagaaa ttcttcaaaa aggattgatg ttggctagtt ttaactttcc ttggttcttc
    17761 ctcatgttag ccattcttgt cctcattgtg atggttcttt atctgtccgc cttcagtcta
    17821 ctcttaggtg gctcagtctt cttacttttt gggtttggac tattggtctt tatccagact
    17881 ggattgatgg agaaaatttt cgcaaaatac caataggagc cttatttctg aaactacttt
    17941 caaacgctcc aaacgctatt ctataagcga gaaactaaaa tctaagtgtc tataagatat
    18001 tgaaagcctt ttcggtaaag tgtatactaa agaagtaaag aaaaatctgc tttagcagaa
    18061 aataaaaata ataggagaaa atctatgtca gatttgaaaa aatacgaagg tgtcattcca
    18121 gccttctacg catgttatga tgatcaagga gaagtaagcc cagaacgtac gcgtgccttg
    18181 gttcaatact tcattgataa aggtgttcaa ggtctttatg tcaatggttc ttctggtgaa
    18241 tgtatctacc aaagtgttga agaccgcaag ttaatcttgg aagaagtcat ggcggtagcc
    18301 aaaggtaaat tgaccatcat tgctcatgtt gcctgcaaca atactaaaga tagtatggaa
    18361 cttgctcgcc atgctgaaag cttgggagta gatgctattg caacgattcc accaatttat
    18421 ttccgcttgc cagaatactc agttgccaaa tactggaacg atatcagttc tgcagctcca
    18481 aacacagact acgtgattta caacattcct caattggcag gggttgcttt gactccaagc
    18541 ctttacacag aaatgttgaa aaatcctcgt gttatcggtg ttaagaactc ttctatgcca
    18601 gttcaagata tccaaacctt tgtcagcctt ggtggggaag accatatcgt ctttaatggt
    18661 cctgatgagc agttcctagg aggacgcctc atgggtgcta gggctggtat cggtggtact
    18721 tatggtgcta tgccagaact cttcttgaaa ctcaatcagt tgattgcgga taaggaccta
    18781 gaaacagcgc gtgaattgca gtatgctatc aacgcaatca ttggtaaact cacttctgct
    18841 catggaaata tgtacggtgt cattaaagaa gtcttgaaaa tcaatgaagg cttgaatatt
    18901 ggatctgttc gttcaccatt gacaccagtg actgaagaag atcgtccagt tgtagaagcg
    18961 gctgctgcct tgattcgtga aaccaaggag cgcttcctct aatataaaag gaggtattta
    19021 tgacatacta cgttgcaatt gatatcggtg gaaccaacat caagtatggt ttggttgatc
    19081 aagaggggca acttcttgaa tcgcatgaaa tgccaactga ggcgcataag ggtggacctc
    19141 atatcttaca aaagaccaaa gatatcgtag ctagttattt agaaaaaggc ccagtagcag
    19201 gtgttgccat atcttctgct gggatggtgg atccggataa gggtgagatt ttctatgctg
    19261 ggcctcaaat ccctaactac gcaggcaccc agttcaaaaa ggaaatcgaa gaaagcttta
    19321 ctattccttg tgagattgaa aatgatgtca actgtgcagg tcttgctgag gcagtatctg
    19381 gttcaggcaa gggagcaagt gtgacacttt gcttgaccat tggaaccggt atcggtggtt
    19441 gcttgattat ggataggaaa gtcttccatg gttttagcaa ttcagcctgt gaagtcgggt
    19501 atatgcatat gcaggatgga gcttttcagg atctcgcttc tacaacagct ttagtgaaat
    19561 atgtagctga agcccatgga gaagatgttg atcagtggaa tggccgacgt atctttaagg
    19621 aagctactga aggaaacaaa atctgcatgg aaggtattga ccgtatggtt gactatctag
    19681 gaaaaggtct ggcaaatatt tgttatgtgg ccaatccaga agtggttatt cttggtggtg
    19741 gtatcatggg gcaagaggct atcctcaaac ctaagatccg cacagccttg aaagaggcat
    19801 tggtaccaag tttagcagaa aaaacacgat tagaatttgc ccatcaccaa aatacagcag
    19861 ggatgttggg tgcatattat cattttaaga caaaacaatc ctagtttggc tcagccaaac
    19921 taggattttc ttacacgttt ttgtctacga tagccgttga gttttttatt ttcccagtag
    19981 ctattaaaga ttttttcctt gctttcgcga ttgatttcca aaaagtaggc ataaatcaaa
    20041 tcgataaaga agagcatagg aagttgagcg gatattcgtt ggatgtagga gggttggctg
    20101 tgggtggcta caagaacagt ctctgtatag gtctggctat ctttattggg aacacttgta
    20161 aagagtacag tctttgcccc catctccttg gcatctaata gactatctaa aatagaagga
    20221 gttgagcctg aaagtgagaa acccagtact agacaatttt catccatgat gctggttgtc
    20281 caggcaaagc cgtcttggtc tgtcaaagct tcgcagacca cacctagtcg cataaaacgt
    20341 aatttcattt cacgggcgac gaggccagaa ctccctgttc caaagaagta gatacgctca
    20401 gcatcttcga ttagctgggc aattcgctct agttggattt cgtcaatcaa gtcttgtgtt
    20461 tgttccctca tgttgctata acttctgagg actcgtttgg tcagtggact gtgcttggaa
    20521 acttggttgg cttgattttc tgcctgatgt tggtattgga aaataaattc tcggtagcca
    20581 gtaaagccac actttttagc aaagcgggtc aaagcagctt gagaaatatg taatttttgg
    20641 gtgacttgtt gagaagataa atcatctgta atcgtttcag cttgcaaaaa atagcgagcg
    20701 atttcttgct ctaggtctgt catttcttca aaatgtgaat caatgatagt tgcgatatct
    20761 ggtttgtcca tagggaaagc tcctttacat gagtcatact ggaagactag atcagggaat
    20821 agtcacactt cattataaca cataatataa ggatagataa ataaaaacgc atctctgttt
    20881 taaaaacgaa aaaatcgaaa aagcttctct cttttccata attttctact caaattgtgg
    20941 tacaattaag agtaagattt taagttagaa atgagactga tttgtatgag aaaatttaac
    21001 agccattcga ttccgattcg gcttaattta ttgttttcaa tcgtcatttt actctttatg
    21061 gccattattg gtcgtttgtt gtatatgcag gttttgaaca aggattttta cgaaaaaaag
    21121 ctagcctcag ctagtcagac caagattaca agcagttcag cccgtgggga aatttatgat
    21181 gctagtggaa aacctttggt agaaaatacg ttaaagcagg ttgtttcctt tacgcgtagc
    21241 aataaaatga cggctacaga cttaaaagaa acagctaaaa agttactgac ttatgtgagc
    21301 atcagttctc caaatttgac agaacgccag ctggcggatt actatttggc tgatcctgaa
    21361 atctataaaa aaacagtgga agctctccca agcgagaaac gcttggattc agatggcaat
    21421 cgtctatccg aatcagaact gtataacaat gcggtcgata gtgtacaaac gagtcaacta
    21481 aactatacag aggatgaaaa gaaagaaatc tatcttttta gtcagttaaa tgctgttgga
    21541 aactttgcga caggaaccat tgcgacagat cctctaaatg attctcaggt ggctgttatt
    21601 gcctctattt caaaggagat gcctggcatt agtatttcta cttcttggga tagaaaggtt
    21661 ttggaaactt ccctttcttc tatagttggg agtgtatcca gtgaaaaagc tggtctccca
    21721 gcggaagaag cagaagccta tcttaaaaaa ggctattctc taaatgatcg tgtaggaacc
    21781 tcctatttgg aaaagcaata tgaagagacc ttacaaggaa aacgctcggt aaaagaaatc
    21841 catctggata aatatggcaa tatggaaagc gtggatacaa ttgaggaagg tagtaaggga
    21901 aacaatatca aactgaccat tgatttggct ttccaagata gcgtggatgc tttactgaaa
    21961 agttatttca attccgagct agaaaatggt ggagccaagt attctgaagg tgtctatgca
    22021 gtcgccctta acccaaaaac aggtgcggtt ttgtctatgt cagggattaa acatgacttg
    22081 aaaacgggag agttgacgcc tgattccttg ggaacggtaa ccaatgtctt tgtgccgggt
    22141 tctgttgtca aggcggcgac catcagctct ggttgggaga atggagtctt atcagggaat
    22201 cagaccttga cagaccaacc gattgtcttc caaggttcag ctccgattaa ttcttggtac
    22261 actcaggctt acggttcatt cccgattaca gctgtggaag ccttggagta ttcttctaat
    22321 gcctatatgg ttcaaacggc tttgggcatt atgggtcaga cctatcaacc caatatgttt
    22381 gttctaacta acaatttaga atccgccatg gggaaacttc gctcgacatt tgcggaatat
    22441 ggtcttggag cctcaacagg cattgacctt ccagatgagt caactggttt tataccaaaa
    22501 gagtataatt ttgctaatta cattaccaat gcctttggtc agtttgataa ctacactcct
    22561 atgcaattgg cccagtacgt tggaaccatt gccaacaacg gtgttcggat tgcacctcac
    22621 attgtcgagg ggatttatgg aaacaatgaa caaggcggct tagggaactt aatccaatct
    22681 gttgaatcca aggaaatgaa taaaattaat atttctgagt ctgatgtttc catcctccaa
    22741 caaggctttt atcaagtgtc acatggtggt agtgctttga caaccggtcg tgccttttca
    22801 aatggcgcaa gcgtatcgat tagtggtaaa acaggtactg ccgaaagtta tgttgagggt
    22861 ggtcaagaag ctaacaatac taatgctgtg gcctatgcac catcagataa tcctcaaatc
    22921 gctgtagctg ttgtcttccc tcataacacc aaccttacaa atggtgtcgg accttccatt
    22981 gcgcgcgata ttatcaacct ctataaccaa catcatccaa tgaattagaa aggaacatat
    23041 gctttatcca acacctattg ctaagctaat tgacagttat tctaagttac cgggtatcgg
    23101 gattaagacg gctacacgtc tggccttcta tactattgga atgtctgatg acgatgtcaa
    23161 tgaatttgct aaaaatctcc tttctgctaa gagagagctg acctactgtt ccatctgcgg
    23221 tcgcctgact gatgacgatc cttgctctat ctgtaccgat ccgactcgtg accagacaac
    23281 gattttagtt ctcgaagata gtcgcgatgt ggcagccatg gagaatatcc aagaatacca
    23341 tggactctat catgtcttgc atggactcat ttctcccatg aatggtatta gtccagatga
    23401 tatcaatctc aagagcctca tgactcgtct tatggatagt gaagtttcag aggtaatcgt
    23461 agcaacaaat gctacagcag atggtgaagc gacatccatg tatctttcac gtttgctcaa
    23521 gccagttggt atcaaggtta cgcgtctagc acgaggtctc gctgtcggag cggacattga
    23581 gtatgcggat gaagtgacgc tcttacgagc cattgaaaat cgaacagagt tgtaagtgta
    23641 ggcaaattta cgaactccat tcatttataa aaaatcaaag aggctgaaaa tcgttcctat
    23701 cggcctcttt ttgtatagtg tgatgagtag gatcaggttc aagttttaaa aaaccaagca
    23761 aatatgatat actaaagagc gagtattcta gtagaattag gacgaataat atgaaacaaa
    23821 cgattattct tttatatggt ggacggagtg cggaacgcga agtctctgtc ctttcagctg
    23881 agagtgtcat gcgtgcggtc gattacgacc gtttcacagt caagactttc tttatcagtc
    23941 agtcaggtga ctttatcaaa acacaggaat ttagtcatga tccggggcaa gaagaccgtc
    24001 tcatgaccaa tgaaaccatt gattgggata agaaagttgc accaagtgct atctacgaag
    24061 aaggtgcagt ggtctttcca gtccttcacg ggccaatggg agaagatggc tctgttcaag
    24121 gattcttgga agttttgaaa atgccttacg ttggttgcaa cattttgtca tcaagtcttg
    24181 ccatggataa aatcacgact aagcgtgttc tggaatctgc tggtattgcc caagttcctt
    24241 atgtggctat cgttgaaggc gatgatgtga ctgctaaaat cgctgaagtg gaagaaaaat
    24301 tggcttatcc agtcttcact aagccgtcaa acatggggtc tagtgtcggt atttctaagt
    24361 ctgaaaacca agaagaactc cgtcaagcct tagaacttgc cttccgatat gatagccgtg
    24421 tcttggttga gcaaggagtg aatgcccgtg aaattgaggt tggcctcttg ggtaactacg
    24481 atgtcaagag cacgctacca ggagaagttg tcaaggatgt tgccttttat gactacgatg
    24541 ccaagtatat tgataacaag attactatgg atattcctgc caaaatcagt gatgatgtgg
    24601 tggctgtcat gcgtcaaaat gcagaaacag ccttccgtgc cattggtggc cttggtctat
    24661 ctcgttgcga tttcttctat acagataagg gagagatttt tctcaacgag ctcaatacca
    24721 tgccaggttt cacccagtgg tctatgtacc cactactttg ggacaatatg gggatcagct
    24781 acccagaact aatcgagcgt ttggttgacc ttgccaagga aagttttgac aagcgcgaag
    24841 cgcatttgat ataaaatgaa agagagggta gaagccagaa ccatcactgc acggtgacta
    24901 gagttctcgg acttcagccc tttttaaagg agtagaaatg aaattaacaa tccatgaaat
    24961 tgcccaagtt gttggagcca aaaatgatat cagtatcttt gaggacaccc agttagaaaa
    25021 agctgagttt gatagtcgtt tgattggaac tggagattta tttgtgccac ttaaaggtgc
    25081 gcgtgatggc catgacttta ttgaaacagc ctttgaaaat ggtgcagcag taaccttgtc
    25141 tgagaaagag gtctcaaatc atccttacat tctagtagat gatgttttga cagcctttca
    25201 atccctagca tcctactatc ttgaaaaaac gactgttgat gtctttgctg ttacaggttc
    25261 aaatggcaag acaacgacta aggatatgtt ggcgcattta ctgtcaacaa gatacaagac
    25321 ctacaaaaca caaggcaatt acaataacga gattggcctt ccttacacag ttcttcatat
    25381 gcctgaaggg acagaaaagt tggtcttgga gatggggcag gatcacttgg gagatattca
    25441 tctcttgtct gaattggctc gtccaaaaac agccatcgtg accttggctg gagaagccca
    25501 tttggccttt ttcaaagacc gttcagagat tgctaaggga aaaatgcaaa ttgcagacgg
    25561 aatggcttca ggttccttgc ttttagcgcc ggctgaccct atcgtagagg actatttgcc
    25621 aactgataaa aaggtggttc gttttggtca aggagcagag ctggaaatta ctgacttggt
    25681 tgagcgcaaa gatagtctga ccttcaaggc caatttctta gagcaagtcc ttgatttgcc
    25741 agtgactggc aagtacaatg cgacaaatgc tatgattgca tcctatgttg ccttgcaaga
    25801 aggagtttca gaggagcaaa ttcatcaggc cttccaaggt cttgaattga cgcgtaatcg
    25861 tactgagtgg aagaaagcag ccaatggagc agatatcctg tcagacgtat ataatgccaa
    25921 tccaactgct atgaagctga ttttagagac tttctctgcc attccagcca atgaaggtgg
    25981 caagaaaatt gcagtgttgg cggatatgaa ggagcttggt gaccagtcta ttcaactcca
    26041 taaccagatg attttgagcc tttctccaga tgtgcttgat accgttattt tctatggaga
    26101 aaatattgct gaattagccc aattggctag tcaaatgttc ccaataggcc acgtttacta
    26161 cttcaagaaa acagaagacc aagaccaatt tgaagaccta gtcaagcagg tcaaagaaag
    26221 ccttggagtc cacgaccaaa tcctgctcaa aggctctaac tctatgaatc tagccaagtt
    26281 ggtagaaagt ttagaaaatg aaaccaagtg attttgttaa gtatctgcaa agaatgattg
    26341 cccttacaga tactggctta acctttacaa aagatccttt tgaccgtgag cgctacgaag
    26401 acttgcgaag tctgttatct gaaatgttga atcaggtatc agacctggat gcagaagaag
    26461 tagcagaagt cttgaaacca acttcagctt atgcgactcc cttaatggac gtccgtgctt
    26521 ggattgttga ggatgagaag atttgtctgg ttaggggaca aggagaggat agttgggctt
    26581 tgccaggtgg ctttggtgaa gtcggctatt ctccaactga aaatattctc aaggaaattg
    26641 aagaagaaac cggttttaaa gccaaagttg aaagactgct agctgttttt gataccaatc
    26701 gtttccaact acagagcaaa caatatgcaa agtttgtttt tgaatgtaag cttctcgatg
    26761 gacaattcca agaaaatcaa gaaatcgctg cccttcaatt ttttgcaatt gaccaactgc
    26821 cgaatttatc tgaaaaacgc attaccaagg agcaaatcga gattctttgg caggtttatc
    26881 aaggtcagag ggagcaatat cttgactaag aagatgatta tcgtatttct aaatccattt
    26941 ttgacaacta gcatggtata ataatatgca ggaaaatttt gaatcatgag gaagactaga
    27001 tgaatttatg ggatattttc tttacgactc aggcaaccga gccgcccaaa tttgaccttt
    27061 tttggtatgt tagcctattt acgctcttag ccttaacctt ttatacagcc catcgctatc
    27121 gtgaaaagaa ggtttaccaa cgatttttcc aaatcttgca gactgttcag ttaatccttc
    27181 tttatggttg gtactgggtc aatcatatgc cactgtcaga aagcctaccc ttttaccatt
    27241 gccgtatggc tatgtttgtg gtactcttgc ttcctggtca gtccaaatat aaacaatact
    27301 ttgcattatt gggaacattt gggacattag cagcctttgt ttatccagtg ccagatgctt
    27361 acccttttcc acatatcacc attctatcct ttatctttgg tcatttagca ctcttgggga
    27421 actctctagt ttatctattg agacagtata atgcgcgatt gctggatgtg aagggaattt
    27481 ttctcatgac ctttgcccta aatgccttga tttttgtggt caatttggtg acaggtggcg
    27541 attacggatt tttgacaaaa ccgccattgg ttggggatca cggtctagta gctaattatt
    27601 tacttgtttc aattgtgctg gtagctacta tcagtttgac taagaaaatc ttagaattct
    27661 ttttagctca agaagcagaa aaaatgattg caaaggaagc ttaacacaga gctttctttt
    27721 ttgctcttag agagttttta caagcagctt ataaaataag aatttctgaa tagacaaact
    27781 caaaaaatgg ctgggaaatt taggaaaaaa gcaagcacga ttaaattttt tgtgttataa
    27841 tattttgtga atagctatgc ctatgtttag ctatggaata atacgaagtg cgaaacttgg
    27901 aagatagaga ggaagcgatg taatggctag agaaggcttt tttacaggtc tagatattgg
    27961 aacaagctct gtcaaggtgc ttgtggccga gcagagaaat ggtgaattaa atgtaattgg
    28021 cgtgagtaat gccaaaagta aaggtgtaaa ggatggaatt attgttgata ttgatgcagc
    28081 agcaactgct atcaagtcag ccatttccca agcggaagaa aaggcaggca tttcgattaa
    28141 atcagtaaat gtcggcttgc ctggtaatct tttgcaggta gaaccaactc aggggatgat
    28201 tccagtaaca tctgatacta aggaaattac ggatcaagat gttgaaaatg ttgtcaaatc
    28261 agctttgaca aagagtatga cacctgaccg tgaagtcatt acctttattc ctgaagaatt
    28321 tattgtggat ggtttccaag ggattcgtga cccacgtggc atgatggggg ttcgccttga
    28381 aatgcgtggt ttgctttata caggacctcg tactatcttg cacaatttgc gtaagacggt
    28441 tgagcgtgca ggtgttcagg ttgaaaatgt tatcatttca ccactagcaa tggttcagtc
    28501 tgttttgaac gaaggggaac gtgaatttgg tgctacagtg attgatatgg gggcaggtca
    28561 aacgactgtc gctacaatcc gtaatcaaga actccagttc acacatattc tccaagaagg
    28621 tggagattat gtaactaaag atatctccaa ggttttgaaa acctctcgca aattagcgga
    28681 aggcttgaaa ctgaattacg gggaagccta tccgcctctt gcaagcaaag aaaccttcca
    28741 agtagaggtt attggagaag tagaagcagt cgaagtgacg gaagcctact tgtcagaaat
    28801 tatttctgca cgaatcaagc acatccttga acaaatcaag caagaattag atagaaggcg
    28861 tctattggac ctccctggtg gtattgtctt aatcggtggg aatgccattt taccaggtat
    28921 ggttgagctt gctcaggaag tctttggcgt ccgtgtcaag ctttatgttc caaatcaagt
    28981 tggtatccgt aatccagcct ttgcgcatgt gattagttta tcagaatttg cgggtcaatt
    29041 aacagaagtt aatcttttgg ctcagggagc gataaaaggt gagaatgact taagtcatca
    29101 gccaattagt tttggtggga tgctgcaaaa aacagctcag tttgtacaat caacgcctgt
    29161 tcaaccagct cctgctccag aagtagagtc ggtggcgcct acagaaccaa tggcggattt
    29221 ccaacaagct tcacaaaata aaccgaaatt agcagatcgt ttccgtggct tgatcggaag
    29281 catgtttgac gaataaagag gaaaaataaa ttatgacatt ttcatttgat acagctgctg
    29341 ctcaaggggc agtgattaaa gtaattggtg tcggtggagg tggtggcaat gccatcaacc
    29401 gtatggtcga cgaaggtgtt acaggcgtag aatttatcgc agcaaacaca gatgtacaag
    29461 cattgagtag tacaaaagct gagactgtta ttcagttggg acctaaattg actcgtggtt
    29521 tgggtgcagg aggtcaacct gaggttggtc gtaaagccgc tgaagaaagc gaagaaacac
    29581 tgacggaagc tattagtggt gccgatatgg tcttcatcac tgctggtatg ggaggaggct
    29641 ctggaactgg agctgctcct gttattgctc gtatcgccaa agatttaggt gcgcttacag
    29701 ttggtgttgt aacacgtccc tttggttttg aaggaagtaa gcgtggacaa tttgctgtag
    29761 aaggaatcaa tcaacttcgt gagcatgtag acactctatt gattatctca aacaacaatt
    29821 tgcttgaaat tgttgataag aaaacaccgc ttttggaggc tcttagcgaa gcggataacg
    29881 ttcttcgtca aggtgttcaa gggattaccg atttgattac caatccagga ttgattaacc
    29941 ttgactttgc cgatgtgaaa acggtaatgg caaacaaagg gaatgctctt atgggtattg
    30001 gtatcggtag tggagaagaa cgtgtggtag aagcggcacg taaggcaatc tattcaccac
    30061 ttcttgaaac aactattgac ggtgctgagg atgttatcgt caacgttact ggtggtcttg
    30121 acttaacctt gattgaggca gaagaggctt cacaaattgt gaaccaggca gcaggtcaag
    30181 gagtgaacat ctggctcggt acttcaattg atgaaagtat gcgtgatgaa attcgtgtaa
    30241 cagttgttgc aacgggtgtt cgtcaagacc gcgtagaaaa ggttgtgtct ccacaagcta
    30301 gaactgctac taactaccgt gagacagtga aaccagctca ttcacatggc tttgatcgtc
    30361 attttgatat ggcagaaaca gttgaattgc caaaacaaaa tccacgtcgt ttggaaccaa
    30421 ctcaggcatc tgcttttggt gattgggatc ttcgccgtga atcgattgtt cgtacaacag
    30481 attcagtcgt ttctccagtc gagcgctttg aagccccaat ttcacaagat gaagatgaat
    30541 tggatacacc tccatttttc aaaaatcgtt aagtaaatga atgtaaaaga aaatacagaa
    30601 cttgtttttc gagaagttgc agaggctagt ctgagtgctc atcgagagag tggttcggtc
    30661 tctgtcattg cagttaccaa gtatgtagat gtaccgacag cggaagcctt gcttccgcta
    30721 ggtgttcatc atatcggtga aaatcgtgta gataagtttc tggaaaaata tgaagcttta
    30781 aaagatcgag atgtgacttg gcatttgatt ggtaccttgc aaagacgtaa ggtgaaagat
    30841 atcattcaat acgttgatta tttccatgca ttggactcag taaagctagc aggggaaatt
    30901 caaaaaagaa gtgaccgagt catcaagtgt ttccttcaag taaatatttc taaagaagaa
    30961 agcaaacacg gtttttcgag agaggaactg ctggaaatct tgccagagtt agccagacta
    31021 gataagattg aatatgttgg tttaatgacg atggcacctt ttgaggctag cagtgagcag
    31081 ttgaaagaga ttttcaaggc ggcccaagat ttacaaagag aaattcaaga gaaacaaatt
    31141 ccaaatatgc ctatgaccga gttaagtatg ggaatgagtc gtgattataa agaagcgatt
    31201 caattcggtt ccacttttgt tcgtataggt acatcatttt ttaagtagga gagaaccatg
    31261 tctttaaaag atagattcga tagatttata gattatttta cggaggatga ggattcaagt
    31321 ctcccttatg aaaaaagaga tgagcctgtg tttactccag taaattcttc acaggaaccg
    31381 gctctcccaa tgaatcaacc ttcacagtcg gctggtacaa aagagaacaa tatcaccaga
    31441 cttcatgcaa gacaacagga attggcaaat cagagtcagc gtgcaacgga taaggtcatt
    31501 atagatgttc gttatcctag aaaatatgag gatgcaacag aaattgttga tttattggca
    31561 ggaaacgaaa gtatcttgat tgattttcag tatatgacag aggtgcaggc tcgtcgttgt
    31621 ttggactatt tggatggagc ttgtcatgtt ttagctggaa atttgaaaaa ggtagcttct
    31681 accatgtatt tgttgacacc agtgaatgtt attgtaaatg ttgaagatat ccgtttacca
    31741 gatgaagatc aacagggtga gttcggtttt gatatgaagc gaaatagagt acgataatga
    31801 tttttttaat tcgtatgatt tataatgcag tggatattta ctccctgatt ttggtagcct
    31861 tcgctgtcat gtcttggttt ccaggtgcct acgaatccag tttaggtcgt tggattgtag
    31921 cgttggtgaa accagtgctt gctcccttgc aacgcctgcc tttacagata gcgggtcttg
    31981 atttatctgt ttgggttgcg attgttttgg ttcgattttt aggagaaaac ctagtgcgtt
    32041 ttctggcgat gataggatga ataaagggat ttatcagcat ttctccatag aagatcgtcc
    32101 atttcttgac aagggaatgg aatggataaa gaaggtagaa gatagctatg ctcctttttt
    32161 aactcctttt atcaatcctc atcaggagaa gctattaaag attttggcca aaacctatgg
    32221 tcttgcttgt agcagtagtg gggaattcgt ctcgagtgag tatgttcgag ttttattata
    32281 cccagattat ttccaaccag agttttcaga ttttgaaata tctctccagg aaattgtgta
    32341 ttccaataaa tttgaatatt taacgcatgc taagatttta gggacagtca tcaatcaatt
    32401 agggattgaa cggaaacttt ttggagatat cctagtagat gaagaacggg cgcagattat
    32461 gattaatcag cagtttcttc ttctctttca agatggacta aagaaaattg gtcgtatacc
    32521 tgtttcgctg gaggaacgtc ctttcaccga gaaaatagat aagctagaac agtatcgaga
    32581 actggattta tctgtgtcta gttttcgatt agatgttctt ttatcaaatg ttttgaaact
    32641 atctaggaat caagcaaacc agttgattga aaagaaactt gtccaagtaa attatcatgt
    32701 ggtagacaaa tcagattaca ctgttcaagt tggagacttg attagtgtga gaaaatttgg
    32761 tcgcttgaga ttacttcaag ataagggaca aacgaaaaaa gagaagaaaa aaataaccgt
    32821 ccagttatta ttaagtaagt gaggaataga atgccaatta catcattaga aataaaggac
    32881 aagacttttg gaactcgatt cagaggtttt gatccagaag aagtcgatga atttttagat
    32941 attgtggttc gtgattacga agatcttgtg cgtgcgaatc atgataaaaa tttgcgtatt
    33001 aagagtttag aagagcgttt gtcttacttt gatgaaataa aagattcatt gagccagtct
    33061 gtattgattg cccaggatac agctgagcga gtgaaacagg cggcgcatga acgttcaaac
    33121 aatatcattc atcaagcaga gcaagatgcg caacgcttgt tggaagaagc taaatataag
    33181 gcaaacgaga ttcttcgtca agcaactgat aatgctaaga aagtcgctgt tgaaacagaa
    33241 gaattgaaga acaagagccg tgtcttccac caacgtctca aatctacaat tgagagtcag
    33301 ttggctattg ttgaatcttc agattgggaa gatattctcc gtccaacagc tacttatctt
    33361 caaaccagtg atgaagcctt taaagaagtg gttagcgaag tacttggaga accgattcca
    33421 gttccaattg aagaagaacc aattgatatg acacgtcagt tctctcaagc agaaatggaa
    33481 gaattacaag ctcgtattga ggtagccgat aaagaattgt ctgaatttga agctcagatt
    33541 aaacaggaag tggaagctcc aactcctgta gtgagtcctc aagttgaaga agagcctctg
    33601 ctcatccagt tggcccaatg tatgaagaac cagaagtagc tccagtgcat ccgacaggtc
    33661 caacaccagc tacagaaact gttgattcag caccgggatt tgaagcaccg caagaatctg
    33721 ttacaatttt ataagaaata ttctgagaac aatatcttat ccttatattc ccagcgagca
    33781 ggagatggtg tgagtcctgc attccctatc gataagatta tcctctcaaa aactcaagtc
    33841 tgaatctagt aagatttgac gttccccacg ttacgggata agagggagaa agactaaaac
    33901 tttttccgaa taaaggtggt accacgattt tcgtcctttt tggaagtcgt ggtttttaat
    33961 ttgttattat ttataaagga gataccatga aactcaaaga cacccttaat cttgggaaaa
    34021 ctgaattccc aatgcgtgca ggccttccta ccaaagagcc agtttggcaa aaggaatggg
    34081 aagatgcaaa actttatcaa cgtcgtcaag aattgaacca aggaaaacct catttcacct
    34141 tgcatgatgg ccctccatac gctaacggaa atatccacgt tggacatgct atgaacaaga
    34201 tttcaaaaga tattattgtt cgttctaagt ctatgtcagg attttacgca ccatttattc
    34261 ctggttggga tactcatggt ctgccaatcg agcaagtatt gtcaaaacaa ggtgtcaaac
    34321 gtaaagaaat ggacttggtt gagtacttga aactttgccg tgagtacgct ctttctcaag
    34381 tagataaaca acgtgaagat tttaaacgtt tgggtgtttc tggtgactgg gaaaatccat
    34441 atgtgacctt gactcctgac tatgaagcag ctcaaattcg tgtatttggt gagatggcta
    34501 ataagggtta tatctaccgt ggtgccaagc cagtttactg gtcatggtca tctgagtcag
    34561 cccttgctga agcagagatt gaataccatg acttggtttc aacttccctt tactatgcca
    34621 acaaggtaaa agatggcaaa ggagttctag atacagatac ttatatcgtt gtctggacaa
    34681 cgactccatt taccatcaca gcttctcgtg gtttgacggt tggtgcagat attgattacg
    34741 ttttggttca acctgctggt gaagctcgta agtttgtcgt tgctgctgaa ttattgacta
    34801 gcttgtctga gaaatttggc tgggctgatg ttcaagtttt ggaaacttac cgtggccaag
    34861 aactcaacca catcgtaaca gaacacccat gggatacagc tgtagaagag ttggtaattc
    34921 ttggtgacca cgttacgact gactctggta caggtattgt ccatacagcc cctggttttg
    34981 gtgaggacga ttacaatgtt ggtattgcta ataatcttga agtcgcagtg actgttgatg
    35041 aacgtggtat catgatgaag aatgctggtc ctgaatttga aggtcaattc tatgaaaagg
    35101 tagttccaac tgttattgaa aaacttggta acctccttct tgcccaagaa gaaatctctc
    35161 actcatatcc atttgactgg cgtactaaga aaccaatcat ctggcgtgca gttccacaat
    35221 ggtttgcctc agtttctaaa ttccgtcaag aaatcttgga cgaaattgaa aaagtgaaat
    35281 tccactcaga atggggtaaa gtccgtcttt acaatatgat ccgtgaccgt ggtgactggg
    35341 ttatctctcg tcaacgtgct tggggtgttc cacttcctat cttctacgct gaagatggta
    35401 cagctatcat ggtagctgaa actattgaac acgtagctca actttttgaa gaacatggtt
    35461 caagcatttg gtgggaacgt gatgccaaag acctcttgcc agaaggattt actcatccag
    35521 gttcaccaaa cggcgagttc aaaaaagaaa ctgatatcat ggacgtttgg tttgactcag
    35581 gttcatcatg gaatggagtg gtggtaaacc gtcctgaatt gacttaccca gccgaccttt
    35641 acctagaagg ttctgaccaa taccgtggtt ggtttaactc atcacttatc acatctgttg
    35701 ccaaccatgg cgtagcacct tacaaacaaa tcttgtcaca aggttttgcc cttgatggta
    35761 aaggtgagaa gatgtctaaa tctcttggaa ataccattgc tccaagcgat gttgaaaaac
    35821 aattcggtgc tgaaatcttg cgtctctggg taacaagtgt tgactcaagc aatgacgtgc
    35881 gtatctctat ggatatttta agccaagttt ctgaaactta ccgtaagatt cgtaacactc
    35941 ttcgtttctt gattgccaat acatctgact ttaacccagc tcaagataca gtcgcttacg
    36001 atgagcttcg ttcagttgat aagtacatga cgattcgctt taaccagctt gtcaagacca
    36061 ttcgtgatgc ctatgcagac tttgaattct tgacgatcta caaggccttg gtgaacttta
    36121 tcaacgttga cttgtcagcc ttctaccttg attttgccaa agatgttgtt tacattgaag
    36181 gtgccaaatc actggaacgc cgtcaaatgc agactgtctt ctatgacatt cttgtcaaaa
    36241 tcaccaaact cttgacacca atccttcctc acactgcgga agaaatttgg tcatatcttg
    36301 agtttgaaac agaagacttc gtccaattgt cagaattacc agaagttcaa acttttgcta
    36361 accaagaaga aatcttggat acatgggcag ccttcatgga ctttcgtgga caagcacaaa
    36421 aagccttgga agaagctcgt aatgcaaaag ttatcggtaa atcacttgaa gcacacttga
    36481 cagtttatcc aaatgaagtg gtgaaaactc tactcgaagc agtaaacagc aatgtagctc
    36541 aacttttgat cgtgtctgag ttgaccatcg cagaaggacc agctccggaa gctgccctta
    36601 gcttcgaaga tgtagccttc acagttgaac gtgctgctgg tgaagtatgt gaccgttgcc
    36661 gtcgtattga cccaacaaca gcagaacgca gctaccaggc agttatctgt gaccactgtg
    36721 caagcatcgt agaagaaaac tttgcggaag cagtcgcaga aggatttgaa gagaaataag
    36781 attgaaaagt ctaggcaaaa ttcaatttga gaagaaaaga caactaattt tatagtctat
    36841 taaacgcatt gtatcacgtt tttgaacacc tgatacgatg cgtttttatt tattttgaaa
    36901 atttgtgagg tgtgactttt tatactcaac aagaatcaaa gagaaactta gcaagctaac
    36961 agtagtaaga taaaatagga atttgatatt agggataaga ttggtaaata gtgtaatatt
    37021 tttacaacaa taaatttata tagttatttc tggtttctga aaagtattat attttatttc
    37081 atattataca aatttttatt ttataatatc agaaaatact ttttttaaaa gcaaatatga
    37141 tacaatttta tttgaaaaaa ataaaaaagg agattttatt atgaaattaa aaacacttgc
    37201 tttaattagt ggtatcgtcg gtcttgtggg aggaatttta cttcttattg gtccttttgt
    37261 cttgttggga acagcggtaa acacagttgc tacaactctt aatggaggag ctactgcagg
    37321 ggctttttca ggtgttgcct tactcttgaa tgccttgaag attgcaaatc ttgttcttgg
    37381 tatcattgct attgtttact ataaaggaga taagcgtgta ggtgcagctc cgtctgtact
    37441 aatgattgtt tttggtggag ttagtctcat tccattctta ggatgggttg gggggattct
    37501 tgttattatc ggaggatctc tattccttgc aacattgaag aaattcaaat cagaagaata
    37561 aaaggtattt tagcatgaaa agaacaaaaa agtttatcgg tataggagta gctctattat
    37621 ctctttttct tctagttgca tgtggaacat aaagttcaaa ggatacttca acaagtaatg
    37681 atgagaagac agtagcaaca tccaatagtt caaaagaaac aatcactttc gatacaccgg
    37741 ttgtaacaga cgatgtgatt gaatcaatac gcacttatgc agattatata gatctttata
    37801 aaaatatttt tgatgattat tttactaaag ctgaggaagg tttcaaaggc acagctatgg
    37861 aaaataatga ctcgtttact aaactaaaag agtcaactca aaaattattc gatgcgcaga
    37921 aaaaaaggtt aaataatgaa gatagaatag aaacagccaa aaacaatgtg attgccaaac
    37981 attgtcaaac agtcctttcc tttttggttt tgactagctt ttttgtgaaa aattgtgtaa
    38041 aatagaatag ataaacgagg ggaaacctcg gaaaatttaa aggagaatcc atctaatggt
    38101 aaaattggtt tttgctcgcc acggtgagtc tgaatggaac aaagctaacc ttttcactgg
    38161 ttgggctgat gttgatttgt ctgaaaaagg tacacaacaa gcgattgacg ctggtaaatt
    38221 gatcaaagaa gctggtatca aatttgacca agcttacact tcagtattga aacgtgctat
    38281 caaaacaact aacttggctc ttgaagcttc tgaccaattg tgggttccag ttgaaaaatc
    38341 atggcgcttg aacgaacgtc actacggtgg tttgactggt aaaaataaag ctgaagctgc
    38401 tgaacaattt ggtgatgagc aagttcacat ctggcgtcgt tcatacgatg tattgcctcc
    38461 aaatatggac cgtgatgatg agcactcagc tcacacagac cgtcgttatg cttcacttga
    38521 cgactcagta atcccagatg ctgaaaactt gaaagtgact ttggaacgtg ctcttccatt
    38581 ctgggaagat aaaatcgctc cagctcttaa agatggtaaa aacgtattcg taggagctca
    38641 cggtaactca atccgtgccc ttgtaaaaca catcaaaggt ttgtcagatg acgagatcat
    38701 ggacgtggaa atccctaact tcccaccatt ggtattcgaa ttcgacgaaa aattgaacgt
    38761 cgtttctgaa tactaccttg gaaaataaaa aattgtaagt ctagaattga tttctaggct
    38821 ttttatgtta gtatggaagt atgataagga ataaaaaaca agattatgta ctggcctaca
    38881 agcaaccagt ttcaaccact tacatgggtt gggaagaaga agctttaccg ataggcaatg
    38941 gttctttagg agcaaaagta tttggcctta taggggctga acggattcaa tttaatgaaa
    39001 aaagtctctg gtctggaggt ccacttcctg atagttcaga ttatcagggt ggaaatcttc
    39061 aggatcagta tgttttttta gctgagattc ggcaggcttt ggagaagaga gattacaatc
    39121 tggctaagga actggctgag cagcacctaa ttgggccaaa aacgagtcaa tatgggacct
    39181 atctgtcttt tggggatatt cacattgagt tcagccagca aggtacgact ttgtctcagg
    39241 tgacggacta tcagagacag ctgaatatta gtaaggcact tgcgacgact tcttatgtct
    39301 ataagggaac gcgatttgaa cgtaaagctt ttgcgagttt tccagatgat ctcttggttc
    39361 aatgttttac taaggaaggg ttggaaactc tagattttac tatagaacta tccttgacct
    39421 gtgatttggc ttctgatgga aagtatgagc aggaaaaatc tgattacaag gagtgtaagt
    39481 tggatattac tgattctcat atcttgatga agggaagagt taaggataat gatctgcggt
    39541 ttgctagtta tctagcttgg gaaacggatg gagatattag agtttggtca gatagggttc
    39601 agatatcagg agccagttat gccaatctct tcttggccgc taagacggat tttgcccaaa
    39661 atcctgctag caattatcgc aagaaactag atttagagca acaggtgata gacttggtgg
    39721 acacagctaa agaaaagggc tatacccaat tgaaatcaag gcatatcgag gactaccaag
    39781 ccttattcca gcgtgttcaa ttggatttgg aagctgatgt tgacgcatcc actacagatg
    39841 atttgttaaa aaattataag ccacaagaag ggcaggcttt ggaggagctg ttcttccagt
    39901 atggacggta tttattgatt agttcgtcca gagactgccc agatgctcta ccagctaacc
    39961 tacagggagt ctggaatgca gtcgacaatc ctccttggaa ttcggactat cacttaaatg
    40021 tcaatctgca gatgaattat tggccagcct atgttaccaa tctcctagag gcggtctttc
    40081 cggtcatcaa ctatgtagat gatttgcgtg tctatggtcg tctagcggct gtaaagtatg
    40141 caggaatcgt ctctcagaaa ggtgaggaga atggttggtt ggttcatact caagcgactc
    40201 cctttggttg gacggcacct ggttgggatt actattgggg ttggtcacca gctgccaatg
    40261 cgtggatgat gcaaaccgtt tatgaaacct attcatttta tagggaccaa gactatctca
    40321 gggagaaaat ttatcccatg ttgagggaaa cggttcgttt ttggaatgcc tttttacata
    40381 aggatcagca ggcgcagcgt tgggtgtctt ctccgtctta ttccccagaa catgggccga
    40441 tttcgattgg caatacttat gaccaatctc tgatttggca gttatttcat gattttattc
    40501 aggctgctca ggaattggga ctggatgagg acttgttgac tgatgttaag gagaagtctg
    40561 atttactaaa tcctttgcaa atcactcaat ctggtcgaat cagggagtgg tatgaggagg
    40621 aagagcagta ttttcaaaat gagaaagtgg aggcccagca tcggcatgct tcccatctag
    40681 tgggactcta tcctggcaat ctctttagct acaagggaca agagtatatt gaagcggcgc
    40741 gtgctagcct caatgatcgt ggaaatggcg gcacaggctg gtccaaggct aataagatca
    40801 atctctgggc gcgtttggga gatggcaatc gagcccataa attattggca gagcagttaa
    40861 agacatccac cttgccaaat ctttggtgta gccatcctcc ttttcagata gatggtaatt
    40921 ttggtgctac tagtggcatg gcagaaatgt tactccagtc tcatgcagct tatctggtac
    40981 ctctagctgc cctacctgat gcttggtcaa caggttctgt ttcaggctta atggcacgtg
    41041 gacattttga agtgagcatg agctgggaag ataaaaaact cttacagttg accattttat
    41101 caaggagtgg aggagatttg cgagtttctt atccagatat tgagaagagt gtgattaaaa
    41161 tgaatcaaga aaaaataaaa gcgaaatgca tggggaaaga ttgtatttcg gtggcaacag
    41221 cagaaggtga tcttgttcaa ttttattttt aataaggatt taagaatata agcagttttc
    41281 aactagttga aaaagcgtta taatgataat aggaagtaat actcaatgaa aatcaaagag
    41341 cacaaactag gaagctagcc gcaggttgct caaaacagtg ttttgaggtt gcagatggaa
    41401 gctgacgtgg tttgaagaga gattttcgag gagtataatt tgtttgatag agggtgggtc
    41461 tgatggctta tattgagatg aaacactgtt acaagcgtta tcaggttggg gacacggaga
    41521 ttgtggccaa tcgtgatgtg aattttgaga ttgaaaaggg ggagctggtt attatccttg
    41581 gagcttcagg tgcaggcaag tcaacagttc ttaacctttt tgggggaatg gataccaatg
    41641 atgaagggga aatctggatt gatggtgtta atattgcgga ttatagttcc caccagcgca
    41701 ccaattaccg tagaaatgat gtggggtttg tttttcagtt ttataatcta gtttctaatc
    41761 tgacagctaa ggaaaatgtg gaactggctt ctgaaattgt gacagatgcc ttgaatcctg
    41821 atcaggtctt gacagatgta ggtctggctc atcgtctcaa taactttcca gcccagcttt
    41881 ctggagggga gcaacagcga gtctccattg cacgcgcggt agccaaaaat cctaaaattc
    41941 tcctttgtga tgaaccgact ggagccttgg attatcagac gggcaagcag gttttgaaaa
    42001 ttctccaaga catgtctcgt caaaagggag cgacggtgat catcgtgact cataatggag
    42061 ctttggcgcc cattgctgat cgcgtgattc aaatgcacga tgccagtgtc aaggatgtgg
    42121 tgctcaacca gcatcctcag gatattgaca gtttggagta ctagcatgat caagcgaaaa
    42181 acttattgga aggacttaat tcagtccttc acaggctcca aggggcgttt tttatccatc
    42241 ttgatcctga tgatgttggg atctctagcc ttagtaggcc tcaaagtaac cagtcccaac
    42301 atggaggcga cagctaatgc ttatttaaca actgctcaaa ccttggattt ggcagtcatg
    42361 tctaactatg gcttggatca agcagaccaa gaagaactaa aacagacgga gggcgcagag
    42421 gtcgagtttg gctatttgac agatgtgact atggataatg ggcaggatgc cattcggctg
    42481 tactccaaac cagagcgaat ttcaaccttt cagctaagaa agggacgact tcctcagtca
    42541 gacaaggaaa tcgctttggc cactcatttg caaggccaat acagcgtggg acaggagatt
    42601 agttttaaag aaaaagaaga ggatcattcc tctttaaaag accatactta taccattact
    42661 ggttttgtgg attcggctga aatcctctcc cagcgagata tgggctacgc aggaagtgga
    42721 agtgggactc tgacagccta tggggtgatt ttacctagtc agtttgatca gaaagtctac
    42781 aatatagctc gtttgaaata tcaagattta gcaggtttaa atgccttttc atcagcttat
    42841 gaagaaaaat ccaagcaaca tcaggaagac cttgaacaaa ctttatcaga taatggcaag
    42901 gtacgtctgc aacttttgaa aaaagaagga caagagtctc tagacaaggg gcaagagacc
    42961 cttgacaagg ctcagactaa tttgcaggaa ggcaagcgtc gtttagcagc tgctcaagct
    43021 cgtatacagg ctcaagaaag tcaactagcc ttgtttcctc aagttcagag agagcaggct
    43081 agtgctcaac ttacccaagc caagcaggaa ttgggcaagg aagaggacaa actaaagcaa
    43141 gctgaacaaa atctagccca agaaaaggaa aaattagaaa aacatcagca agtcttggac
    43201 gatttggcgg agccaaggta tcaggtctat aatcgtcaga ccatgccagg tggtcagggc
    43261 tatcttatgt atagcaatgc ttcatccagt attcgagcag tgggcaatat ctttcctgtg
    43321 gtactttatg ccgtagcatc catagtgacc tttacgacca tgactcgctt tgtagacgaa
    43381 gagcgaactc atgcagggat ttttaaggcc ttgggttacc gtagtaagga tattatcacc
    43441 aagtttctcc tttatggact agtagctggg actgtcggaa cggctctagg tagtatactt
    43501 ggtcattatt tgctagccag tgtaatttca agtgtcatta caaaaggcat ggtggtggga
    43561 gaaacccaga ttcagttcta ttggacctat agcttactag ctcttgtctt gagttggttg
    43621 gcgagtgtgt taccagccta tctggtggct tggagggaac ttcatgccga agcagcccag
    43681 cttctacttc ctaaacctcc tgtcaaagga gctaaaatct tattggagcg tatcggtttt
    43741 atctggcgtc gtctcagttt tactcataag gtaacagccc gcaacatctt tcgttataag
    43801 cagagaatgt tgatgacaat ctttggtgtg gcaggttctg tagctctgct ctttgcaggt
    43861 ttgggaatcc aatcttctgt agcaggagtt ccgtctaaac agtttcaaca aatccaacag
    43921 tatcagatgc ttgtctctga aaatcctagt gcgaccgatc aggacaaggt agagctagca
    43981 gaagtgttga aagggcagga gatactagcc taccagaaaa tctattctaa aacgctagac
    44041 aaggatttca aaggcaaggc tggtcttcaa aacattactc ttatgatgat agagaaggaa
    44101 gatttgactc cctttatcca tcttcaacat catcagcagg agctgacatt aaaagatggc
    44161 atcgttatta cagctaaact cgcccagctg gcaggtgtca aggttgggca gactttagaa
    44221 attgaaggta aggaactaaa ggtcgctgct attactgaga actacgttgg tcactttatt
    44281 tatatgagtc aggctagcta tgagcaactt tacggacagc taccccaagc caacacttat
    44341 ctggtctcat taagggatac cagtgcaact agtatcgaaa gtcaggcggg cttgcttatg
    44401 aatcaatctg cggtgtccag cgttgtccaa aatgtttcag ccattcgact cttcgactct
    44461 atcgctagct cactcaatca gaccatgacc atcttggtca tcgtatcggt tctattagct
    44521 attgtcatcc tttacaattt gaccaatatc aacgtagctg agagaatccg tgaactctcc
    44581 actatcaagg ttctcggttt tcataataat gaagtcacac tctacattta ccgtgagacg
    44641 attgtgctgt cccttgtggg aatcgtactt ggtctggtag ctggtttcta tttacaccaa
    44701 tttttgattc aaatgatttc gccttcgact attctctttt atccgcaggt aggctgggaa
    44761 gtctatgtaa tcccagtggt agcagtaagc atcattttga ccttgcttgg tttcttcgtc
    44821 aattattatc tgagaaaggt tgatatgtta gaagccctga aatctgtaga gtaaggtagt
    44881 tatttttagc tgattgaact tctatttact aatattcaaa aatcctccgt ttcaaagagc
    44941 agggaactct ttgtgacaga ggattttttc tatagggctt tagcagctgc aattgcggct
    45001 tcgaagtttg gctcagaatt gatattatcc acgtattcaa cgtagcgaat cgtattgtca
    45061 gtatcgagga caaagactgc gcgtgctaat aggtgccatt cgttgatcaa gagggcataa
    45121 tcgtgcccga aagaatggtc aaagtagtct gaaagcataa tggcattgtc aaggccttca
    45181 gcaccgcacc aacgtttttg agcaaaaggt aggtccattg aaacagtcaa tacgaccgtg
    45241 ttgtccagtc cagccaattc ttcattaaaa cgacgtgttt gagttgagca gatgcctgta
    45301 tcgatagaag gaacgacact caagactttt ttcttgccat caaaatcagc cagagatttt
    45361 ttagaaagat ctgttgtagt aagagaaaaa tcaagcgcct tgtcgccgac ttgtagttgt
    45421 ttacctgtaa agctcacagg atttccgaga aaagttacca taggatactc caatcttttt
    45481 tcttccattg tatctgaaac agtcagaatt ttccaatgat ttgaccggaa atgtgggcat
    45541 agaaaaaacg ccagctcaca tgagaatgac gtttttcaaa ggcttatttt gccaatcctt
    45601 cagcaatctt gtcaaggttg tatttcatca tgctgtagta gctgtcgcct tctttacctt
    45661 gttctgcgat agagtcagta aagatttgtg cgtagattgg gatgtttgtg tcttgagaaa
    45721 cggttttcat tggacggtca tccacacttg attctacaaa gagtgatgga acttttgttt
    45781 ggcgaagttt ttcaaccaag gtcttgattt gttcaggagt tccttcttct tcagtattga
    45841 tttcccagat gtaggcactt ggaacaccat aggctttaga gaagtatttg aatgctcctt
    45901 cgctggttac aatgagtttc ttttcagcag ggatcttatt aaatttatcc ttactttctt
    45961 tatcaagttt gtctaactta tcagtatatt ctttgagatt tttttcatag aattctttat
    46021 tgttagggtc tttggcgctc aattgtttgg cgatattttt agcaaaaata ataccgtttt
    46081 caaggttaag ccaagcgtgt gggtcttctt ttcctttttc attttgacct tcaaggtaga
    46141 taacatcaac gccgtcgctg actgcgaagt agtctttgtt ttcagttttc ttggcatttt
    46201 ctaccaattt tgtaaaccaa gcattgccac ctgtttcaag gttgataccg ttatagaaaa
    46261 tcaaatcagc ctcagaagtt ttcttaacgt cttcaggaag tggttcgtat tcgtgtgggt
    46321 cttgcccaat cggaacgata ctatgaaggt caattttgtc accagcaata tttttagtaa
    46381 tatcagcgat gattgagttt gtagcaacaa cttttagttt ttgaccagaa gttgtatctt
    46441 tttttccgct agcacatgct acaagaatga ttgcagaaag aaagagaacg agtaatgtac
    46501 ctaatttttt cattagatcc tccaatttat tagggctttg ccccttattt taacaaatgt
    46561 ttatttttca gtttcaaata tcgttgtttg ggagcgataa agaagctaat gagaaagaaa
    46621 ctagcagctg taagcacgat actagaacct gccgcaacat taaaactata gccaataaag
    46681 agtcccaaaa ctgaagcagt agctccgaag gttgaggaaa ggaaaatcat acttttcaga
    46741 ctattagcat acagataagc agttgcagct ggggtaatca gcatggctac aatcaggata
    46801 gttccgacac tttgcatggc tgtcacagac acgagagtca ggagtaccat gagaaggtag
    46861 tgatagaaat tgacaggcat tcccatggct ttagccaaga gttcatcaaa ggaagttatc
    46921 aagagttgct tgaagaaaat ccagattaac aagaggatgg ctgcccccac acccatagta
    46981 ataaacatat ccgtatcttg gacggccaga atattaccaa aaaggatatg gaaaaggtca
    47041 gttgaacttt tagcgacacc aatcaagatg ataccgaggg ctaagaaaga agaaaaggta
    47101 atgccgatgg cggtatcgct tttgataatc gagtttcctt tgatgtaggt aatgatgatg
    47161 gcagctagca atccaaagac aatggctccg ataaagaagt caaggcccaa gatgaaggag
    47221 agggctacac ctggtaagac agcatgtgaa atggcatctc ccatgagtga catcccgcgt
    47281 agaataatga aacatcccac agctccagct acaatcccga cgacaatagc tgttatcaag
    47341 gcattttgta ggaaatggaa tttttgcaat ccatcgataa attctgcaat cataggtcac
    47401 ctccattgaa aaagagttga ttaccgtaag cttcttttag attggtttcg gtaaaagttt
    47461 cttttgttgg accaaaggca atcacttctc gattgacaag taagacttga tcgaagtagt
    47521 ggggaatctt gctgaggtcg tggtgaacga tgagaaccgt cttcccagct tttttcaaat
    47581 ctctcagcgt attcatgatg atttcctcac tgacagagtc aatcccagca aagggttcat
    47641 ccaagaggat atagtcggct tcctgcacca aacatctggc aatcaagacc cgctggaatt
    47701 gacctccaga cagttgacta atttgacgtt cagcgtagtc agctaggccg acgatttcaa
    47761 gggcctcttg cactttcttc caatgtttag cctttaaact tcgaaagaga ggaatagagg
    47821 gaaatagtcc taacgagacg cattccttga ccttgatggg aaagttgtag tcgatattga
    47881 ttttttgttc gacataggca attcggtgta aggatttttt aacttccttg tcatcgagaa
    47941 atgcctgacc ttgatgtggg ataattccca acataccttt taatagtgtt gatttcccag
    48001 cgccgtttgg accaatgatg ccggtaattg ttggtccatg gagcactagt gaaatatcct
    48061 taagtgccaa cgtttctttg taggagacac tgaggttttc gatacgtatc ataaacttgt
    48121 attcctcctg tctcttaata tacattaaaa aaaaaattaa gtcaagttaa tttttgaaaa
    48181 aattaaaata ataactgaaa aatagattct aaaaataact ttcaggataa atttctaaat
    48241 tataaaacgc atagtatcaa gtgtaaaaaa cttggaatta tgcgttttat catggaaaga
    48301 ttttttataa tagctaaaaa ataatagtta aatggttatt aattgcattc cctagtgatt
    48361 tttgttaaga taaatgcaaa tacaaatgaa agcgagaaca agatgacacg ttatcaagat
    48421 gatttttatg atgctatcaa tggagaatgg caacagacag ctgaaatccc agcagataag
    48481 tctcaaactg gaggttttgt tgatttagac caggaaattg aagacctgat gctggcgaca
    48541 acagacaagt ggttagcagg tgaagaagtg cctgaggatg ctatcttgga aaactttgtc
    48601 aaataccacc gcctagttcg tgattttgac aagagagaag ctgacggtat cacacctgtc
    48661 ttaccactcc ttaaagaatt ccaagaattg gaaacttttg cggattttac agctaaacta
    48721 gcagagtttg agcttgcagg aaaaccaaac ttccttcctt ttggtgtatc gccagacttt
    48781 atggatgcta gaatcaatgt tctatgggct agcgctccaa gcacaatctt gccagatacg
    48841 acctactatg cagaagaaca tcctcagcgc gaagagctct tgactctttg gaaagaaagc
    48901 agcgcaaatc tcctcaaggc ttatgatttc tctgatgaag aaattgaaga cttgctagaa
    48961 aaaagacttg aattggaccg ccgagttgcg gcagtggtgc tctctaatga agaaagttca
    49021 gaatatgcta aactctatca tccatattct tacgaagatt ttaagaaatt cgcgcctgcc
    49081 ctacctttgg atgacttctt caaagcagtt attgggcaat taccagacaa ggttattgta
    49141 gacgaggaac gtttctggca agcagcagag caattctaca gtgaggaagc ctggtctctc
    49201 cttaaagcaa ccttgatttt gagtgttgtc aatctttcaa ccagctattt aacagaggat
    49261 atccgtgttt tgtctggtgc ctacagccgt gccctttctg gagttccaga ggcaaaagat
    49321 aaggtcaaag cagcttatca tctagcacaa gaacctttca agcaagccct gggtctttgg
    49381 tacgcccgtg agaagttctc tccagaagcc aaggcggatg tggagaaaaa agtggcaacc
    49441 atgattgatg tctataagga gcgtctgctt aagaatgact ggctcactcc agaaacctgt
    49501 aaacaggcta tcgtgaagct caatgtgatc aaaccttata ttggctatcc agaagaattg
    49561 cctgcacgtt acaaggataa ggtagtgaat gaaactgcca gtctttttga gaatgctcta
    49621 gcctttgcgc gtgtggaaat caagcacagt tggagtaagt ggaaccagcc tgtagactat
    49681 aaggaatggg gcatgcctgc tcatatggtc aatgcctact acaatcctca gaagaacctg
    49741 attgtctttc cagcggccat tttacaggcg cctttctatg acttgcatca gtcatcttct
    49801 gctaactacg gtggtattgg ggcagtgatt gcccatgaaa tttcccacgc ctttgatact
    49861 aacggggctt cctttgacga aaatggtagc ctcaaggatt ggtggacaga gagcgactat
    49921 gctgccttca aggagaaaac acaaaaagtc attgaccaat ttgatggaca ggattcttat
    49981 ggagcaacca ttaacggtaa attgactgta tcagaaaacg tggctgactt gggaggaatc
    50041 gcagcagcgc ttgaagcagc taagagagaa gcagacttct cagcagaaga gttcttctac
    50101 aacttcggtc gcatctggcg catgaaaggt cgaccagaat ttatgaaact tttggctagc
    50161 gtcgatgtgc acgcaccagc caaactccgt gtcaatgtgc aagtaccaaa cttcgacgat
    50221 ttctttacaa cctatgatgt caaagaagga gacggaatgt ggcgttcacc agaggagcgc
    50281 gtgattattt ggtaatacaa aaaatctagt catcagaaaa aaggcatcca atcacgtgtg
    50341 aaaaccttga taggatgcct tttgtaatag aaagatttgc tggatagttt acttaaattt
    50401 cgattgtcat catcttgcta gaaaaaggga ttgaaggcct tttcgtgagc gatagtagta
    50461 gctggaccat gtcctggata gacatcgtag tttggtaggg tgaagagttg ggtctggata
    50521 ctatgaagga gttgctccat gctaccagtc ggaaggtcgg tccgtccgat agtttcgcgg
    50581 aatagagcat ctcccgtcaa gactaggtga gcatcaggaa agactaggga aacaccaccg
    50641 atagagtgcc ctggggtcgg tagaacctta aaacgaaatt cctctagttg gtattcttcg
    50701 tgaaagacaa aggtgtgttc tgcaggtttt gtgaccacat ctgccatatc atcgtggcga
    50761 gggagaccgg agagattatc gacaggagtg tagagccagc tggcttcgct ctctgcgata
    50821 tagacaggag gattgccaaa cgtctcgcga accaagtcca gactcatgat atggtcataa
    50881 tgggcgtggg tcaagagaat agcacagatc ggtttgttga tcttctcgat tgtctgacga
    50941 atggcttccc aatgactacc aggatcgacg acgatgaggt gcttttcgcc ttctagataa
    51001 taggtatttt cataggcaac aggattcacg gttttatgga ttttcatact agctccaatc
    51061 tcaaagaatg tactaatact cttcgaaaat ctcttcaaac cgcgtcaact ttatctgcaa
    51121 cctcaaagca gtgctttgaa cagcctgcgg ctagctttct agtttgctct ttgattttca
    51181 ttgagtataa attaagtata gcacagttag ggagaatagg taaggattta aaatgaactt
    51241 aaaaaccagc atgactagat gaagacaggc tggttatcaa tttatcaata ttggaaaggt
    51301 gtcaattgcc cttcataggt tgcataaact ccgtcattag cttgtttgat agacgtgatg
    51361 tttagagtgc taccgtagtt ggcttatcat ttgtcgctat attcactata agttatccta
    51421 ctgggcaggt tctggtcgtt agcatagtat tgaacgagtt ttttatagct ttgctggctg
    51481 aataggaaca ggcagcaaac tcctaacatt aggagagcaa agatagaaat agcagttttt
    51541 ttcataggta ttctccttat aaactaaagg atagaagaaa gtatcttgag gatttttata
    51601 ctcttcaaaa atctcttcaa accgcgtcaa caatctcttc aaaccgcgtc aacgtcgcct
    51661 tgccgtatat atgtgactga ctt
//
LOCUS       DAVAGB010000011        48990 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVAGB010000011 DAVAGB010000000
VERSION     DAVAGB010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48990
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.011"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(187..2076)
                     /locus_tag="VQO19_000692"
     CDS             complement(187..2076)
                     /locus_tag="VQO19_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HET1348986.1"
                     /translation="MKKTFFLLMFGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            2215..3780
                     /locus_tag="VQO19_000693"
     CDS             2215..3780
                     /locus_tag="VQO19_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET1348987.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAIKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLIKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            3780..4520
                     /locus_tag="VQO19_000694"
     CDS             3780..4520
                     /locus_tag="VQO19_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET1348988.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(4629..4844)
                     /locus_tag="VQO19_000695"
     CDS             complement(4629..4844)
                     /locus_tag="VQO19_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348989.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNTREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(5715..6965)
                     /gene="ilvA"
                     /locus_tag="VQO19_000696"
     CDS             complement(5715..6965)
                     /gene="ilvA"
                     /locus_tag="VQO19_000696"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HET1348990.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(7015..7371)
                     /locus_tag="VQO19_000697"
     CDS             complement(7015..7371)
                     /locus_tag="VQO19_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET1348991.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(7609..7845)
                     /locus_tag="VQO19_000698"
     CDS             complement(7609..7845)
                     /locus_tag="VQO19_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1348992.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(7952..8974)
                     /gene="ilvC"
                     /locus_tag="VQO19_000699"
     CDS             complement(7952..8974)
                     /gene="ilvC"
                     /locus_tag="VQO19_000699"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET1348993.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILVPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(9040..9516)
                     /gene="ilvN"
                     /locus_tag="VQO19_000700"
     CDS             complement(9040..9516)
                     /gene="ilvN"
                     /locus_tag="VQO19_000700"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HET1348994.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(9509..11209)
                     /locus_tag="VQO19_000701"
     CDS             complement(9509..11209)
                     /locus_tag="VQO19_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HET1348995.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYLPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(11410..13077)
                     /locus_tag="VQO19_000702"
     CDS             complement(11410..13077)
                     /locus_tag="VQO19_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HET1348996.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLTDIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(13080..13445)
                     /locus_tag="VQO19_000703"
     CDS             complement(13080..13445)
                     /locus_tag="VQO19_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET1348997.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(13602..13790)
                     /locus_tag="VQO19_000704"
     CDS             complement(13602..13790)
                     /locus_tag="VQO19_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HET1348998.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(13906..14082)
                     /locus_tag="VQO19_000705"
     CDS             complement(13906..14082)
                     /locus_tag="VQO19_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET1348999.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            complement(14193..14390)
                     /locus_tag="VQO19_000706"
     CDS             complement(14193..14390)
                     /locus_tag="VQO19_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET1349000.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            complement(14645..16189)
                     /locus_tag="VQO19_000707"
     CDS             complement(14645..16189)
                     /locus_tag="VQO19_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HET1349001.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            16402..16704
                     /gene="gatC"
                     /locus_tag="VQO19_000708"
     CDS             16402..16704
                     /gene="gatC"
                     /locus_tag="VQO19_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HET1349002.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVVEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            16704..18170
                     /gene="gatA"
                     /locus_tag="VQO19_000709"
     CDS             16704..18170
                     /gene="gatA"
                     /locus_tag="VQO19_000709"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HET1349003.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLNSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            18170..19612
                     /gene="gatB"
                     /locus_tag="VQO19_000710"
     CDS             18170..19612
                     /gene="gatB"
                     /locus_tag="VQO19_000710"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HET1349004.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            19741..20301
                     /gene="efp"
                     /locus_tag="VQO19_000711"
     CDS             19741..20301
                     /gene="efp"
                     /locus_tag="VQO19_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HET1349005.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            20323..20712
                     /locus_tag="VQO19_000712"
     CDS             20323..20712
                     /locus_tag="VQO19_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET1349006.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            20705..21127
                     /gene="nusB"
                     /locus_tag="VQO19_000713"
     CDS             20705..21127
                     /gene="nusB"
                     /locus_tag="VQO19_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HET1349007.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(21176..21412)
                     /locus_tag="VQO19_000714"
     CDS             complement(21176..21412)
                     /locus_tag="VQO19_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET1349008.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(21425..21898)
                     /locus_tag="VQO19_000715"
     CDS             complement(21425..21898)
                     /locus_tag="VQO19_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349009.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(21916..22101)
                     /gene="briC"
                     /locus_tag="VQO19_000716"
     CDS             complement(21916..22101)
                     /gene="briC"
                     /locus_tag="VQO19_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HET1349010.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(22364..23131)
                     /locus_tag="VQO19_000717"
     CDS             complement(22364..23131)
                     /locus_tag="VQO19_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HET1349011.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(23128..23994)
                     /locus_tag="VQO19_000718"
     CDS             complement(23128..23994)
                     /locus_tag="VQO19_000718"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HET1349012.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(24031..25398)
                     /gene="accC"
                     /locus_tag="VQO19_000719"
     CDS             complement(24031..25398)
                     /gene="accC"
                     /locus_tag="VQO19_000719"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HET1349013.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(25410..25832)
                     /gene="fabZ"
                     /locus_tag="VQO19_000720"
     CDS             complement(25410..25832)
                     /gene="fabZ"
                     /locus_tag="VQO19_000720"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HET1349014.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(25829..26314)
                     /locus_tag="VQO19_000721"
     CDS             complement(25829..26314)
                     /locus_tag="VQO19_000721"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HET1349015.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(26317..27552)
                     /gene="fabF"
                     /locus_tag="VQO19_000722"
     CDS             complement(26317..27552)
                     /gene="fabF"
                     /locus_tag="VQO19_000722"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HET1349016.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFIKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEYAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAVKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(27574..28305)
                     /gene="fabG"
                     /locus_tag="VQO19_000723"
     CDS             complement(27574..28305)
                     /gene="fabG"
                     /locus_tag="VQO19_000723"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HET1349017.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(28339..29259)
                     /gene="fabD"
                     /locus_tag="VQO19_000724"
     CDS             complement(28339..29259)
                     /gene="fabD"
                     /locus_tag="VQO19_000724"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HET1349018.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPVVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEATVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(29252..30226)
                     /gene="fabK"
                     /locus_tag="VQO19_000725"
     CDS             complement(29252..30226)
                     /gene="fabK"
                     /locus_tag="VQO19_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HET1349019.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(30345..30569)
                     /locus_tag="VQO19_000726"
     CDS             complement(30345..30569)
                     /locus_tag="VQO19_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET1349020.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(30629..31603)
                     /locus_tag="VQO19_000727"
     CDS             complement(30629..31603)
                     /locus_tag="VQO19_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HET1349021.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLISLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(31603..32037)
                     /locus_tag="VQO19_000728"
     CDS             complement(31603..32037)
                     /locus_tag="VQO19_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET1349022.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(32131..32916)
                     /locus_tag="VQO19_000729"
     CDS             complement(32131..32916)
                     /locus_tag="VQO19_000729"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HET1349023.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            33241..34605
                     /locus_tag="VQO19_000730"
     CDS             33241..34605
                     /locus_tag="VQO19_000730"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HET1349024.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            34608..34979
                     /locus_tag="VQO19_000731"
     CDS             34608..34979
                     /locus_tag="VQO19_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HET1349025.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIARKKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            35193..36467
                     /gene="serS"
                     /locus_tag="VQO19_000732"
     CDS             35193..36467
                     /gene="serS"
                     /locus_tag="VQO19_000732"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HET1349026.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSATKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(36492..37391)
                     /locus_tag="VQO19_000733"
     CDS             complement(36492..37391)
                     /locus_tag="VQO19_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HET1349027.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDMLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPERRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(37501..38049)
                     /locus_tag="VQO19_000734"
     CDS             complement(37501..38049)
                     /locus_tag="VQO19_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HET1349028.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(38267..39589)
                     /locus_tag="VQO19_000735"
     CDS             complement(38267..39589)
                     /locus_tag="VQO19_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HET1349029.1"
                     /translation="MLELLKSIDDFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPVITALVLSVFVAIAVFGGLKSISKVSTTVVPFMTIIYI
                     LGTLIVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(39680..39768)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(39932..42268)
                     /locus_tag="VQO19_000736"
     CDS             complement(39932..42268)
                     /locus_tag="VQO19_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HET1349030.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHATEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSCVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(42372..42920)
                     /locus_tag="VQO19_000737"
     CDS             complement(42372..42920)
                     /locus_tag="VQO19_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HET1349031.1"
                     /translation="MISFLLLLILVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(42917..43219)
                     /gene="zapA"
                     /locus_tag="VQO19_000738"
     CDS             complement(42917..43219)
                     /gene="zapA"
                     /locus_tag="VQO19_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HET1349032.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            43306..44187
                     /locus_tag="VQO19_000739"
     CDS             43306..44187
                     /locus_tag="VQO19_000739"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HET1349033.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            44191..44805
                     /gene="lepB"
                     /locus_tag="VQO19_000740"
     CDS             44191..44805
                     /gene="lepB"
                     /locus_tag="VQO19_000740"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HET1349034.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            45084..47450
                     /locus_tag="VQO19_000741"
     CDS             45084..47450
                     /locus_tag="VQO19_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HET1349035.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMILAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQTCMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGKQKSQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGVALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(47498..48781)
                     /locus_tag="VQO19_000742"
     CDS             complement(47498..48781)
                     /locus_tag="VQO19_000742"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HET1349036.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
BASE COUNT        14375 a        11202 c         9231 g        14182 t
ORIGIN      
        1 aattaacaca ggattacctt tgaaaaaatg gactttttca agggcttttt gccgtgctct
       61 aaaatcatcg ccaaatcatc aaattgaaat aagaaatagt ttagataaaa ctattgactt
      121 ttcttatagt ttgtctttct tctatcttcc attatatcat actttttcag tctatggtag
      181 ctctctttaa aaggctccga tactgccgcc acctccgcct ccagagaagc caccgccaga
      241 acttccactt ccagaagata cggagtaggt acttgctgta tttgcgacac tagcataatg
      301 gctcatttgc gcgcttgaat gataaaacat actgtgccag ccataagcta catagagatt
      361 gatatctgga ttttcaactt gaatctgatg aaccttcatc aaatgactaa ccttgtccgc
      421 atagccaaat aaggttgcat agaccaagag acgattccaa acaacaatac tttccaattc
      481 agccttatcc agtcgtgcaa tctcacgtaa catattttca aaactggtcc agagatagta
      541 gacctcagct cccgcttcat ttagaacacc atcacgatta tctagtcgaa gcttccaata
      601 atagaaaaca gacaaaacta accctagaaa accaagtatt ggcaaaggga ggtaaagata
      661 gccatgaacg tctaaactgt acaagaacaa accaaatccg ataaataggg gcaagatagt
      721 caagacaccc atacccactt gcaaagcctt ttccaaacca gttaaaggac gatagtaatc
      781 tgggagcccc cagaaggaaa ctcgttttct cactccttct tgcatctggt tcaatacctc
      841 ttcaaaagaa gatttgagtt gaagccctct tgcttgaatc cgtttttcat cagaaacttt
      901 ggctctacga taaagactat cagatacctt gtaatccgca aacaaattgg aaagagtttc
      961 ttctttttta cctgaaaaag ctagatttag gcagtctttc tcaaagcttg acaaaccatc
     1021 ttcttttact agcctcaaac caactgcatc tccttctgaa atgatagaga cattcccacg
     1081 gtctatcaca tctagcaagg tagcttgaat aagttgatca aaggtgaatt ttccagctcc
     1141 cttgaccaag ggactcactt cctccaagga ggtcgagtag actgcttctg ataaaaccat
     1201 aggctctaat tccattgggg gttcatagag acgatgattt ttagcatatt tgactgaagg
     1261 agtggtcttt cttctataaa taaaatagaa gcagacactc aataacaagg agatagaaag
     1321 tatcgaaggg aggacccaag taacgagttg tttactctga tctttttctc taacaatcga
     1381 gtcttctatc ttattaaact cttctaaacg attccctttc aatccctgat ccctagcgct
     1441 agcaaaatcg gtccgaggcc aataggcatg caactcaact ccacgcttag ccggaagatt
     1501 gtctaaacgg atagtatagt caaggttact cttttcaatc gttccctctc taaaaagttt
     1561 ccctgtatgg aaaaagagtt tttcagcccc cttgtctccc cttacatgaa attcaaactt
     1621 ttcaatagac tctgaactat ctgtcagagg ttgccaattt aattcagcga tatcatcata
     1681 aaggaaaagt aaatttttta agttccagac gaggtcaact tcaactatgt cgccctcctg
     1741 acctggatta tagactctca cagtataacc atccgcttct tctgttactt cgctagtcac
     1801 atctgctagt tctgcaccgt ttttcgcggc ctgaaccttt ggatgagggt caatgtcaaa
     1861 cccgctaggc atcttaccag cacgtccaag tcccacgatt tgtcccttaa agtcctcctc
     1921 aaactgataa actatctttt gtctaaattc tgccgtattg tctgcatgaa tatacaaatc
     1981 accttgataa gagtttatct taaaatcaat ggcgaaaaca gaaagtggca gaaggcaaaa
     2041 caagccaaac atcagtaaga aaaaagtttt tttcatcaat taagccccct ttttatcttt
     2101 cttatcatta tagcattttt tcgtaagtaa aggcttactt atgttgaaaa attacgcatt
     2161 tttcgataaa ataggagaca gttatttttt aatagattag aaataggaga aatcatgaga
     2221 aaaatatact tatctatttt cacaagtctc ttgctgatgc taggacttgt caatgttgct
     2281 caagccgatg aatatttacg catcgggatg gaagcagcat atgctccctt taactggacc
     2341 caagatgatg atagcaatgg agctatcaaa atcgatggaa ccaaccagta cgccaatgga
     2401 tacgatgtcc aaattgccaa gaaaatcgct aaggacttag gtaaagaacc tttggttgtt
     2461 aaaaccaagt gggaaggtct agtccctgcc cttacttctg gtaagattga catgattatc
     2521 gcaggtatga gtcctactgc cgaacgcaaa caagaaattg ccttttcaag cagttactat
     2581 actagcgaac cagttttgct tatcaaaaaa gattctgcct acgcaagtgc taaatctttg
     2641 gatgacttta acggtgcaaa aatcacttct caacaagggg tctacctcta cgacttgatt
     2701 gcacaaatcc caggtgctaa aaaagaaaca gccatgggag acttcgctca aatgcgccaa
     2761 gctcttgagg ctggtgtcat tgatgcttat gtttctgaac gtccagaagc actgactgct
     2821 gaagctgcga actctaagtt caagatgatt caagtagaac ctggtttcaa aactggggaa
     2881 gaagatacag ctatcgctat cgggcttcgt aaaaatgaca atcgtattag ccaaatcaat
     2941 gccagcattg aaaccatttc aaaagatgac caagttgcct tgatggatcg tatgatcaag
     3001 gaacaacctg ccgaagctac aacaactgaa gagactagca gtagtttctt tagccaagtc
     3061 gctaaaattc tttctgaaaa ctggcaacaa ctcttgcgtg gtgctggtat cactctttta
     3121 atctctatcg tcggaaccat cataggtctc attattggac ttgccattgg tgtcttccgt
     3181 actgctcctc tctctgaaaa caaagccatt tatggccttc aaaaactagt cggctgggtt
     3241 ctcaatgtct acattgaaat tttccgtggt acgccaatga ttgttcaatc gatggttatc
     3301 tactatggaa ctgcccaagc tttcgggatc aaccttgacc gtacactggc tgctatcttc
     3361 atcgtttcaa tcaataccgg tgcctacatg actgaaatcg tccgtggtgg tatcctagca
     3421 gttgacaagg gacaatttga agctgcgact gctcttggta tgacccataa ccagaccatg
     3481 cgtaagattg tcctacctca ggtagtccgt aacatcctac ctgcaactgg taatgaattt
     3541 gtcatcaata tcaaagatac atctgtattg aacgttatct ctgttgtcga actttatttc
     3601 tcaggaaata ccgtggcaac acaaacctat caatacttcc agacatttac aatcatcgcc
     3661 gtgatttact ttgtcctcac cttcaccgta acacgtatcc tacgctttat cgagcgcaga
     3721 atggacatgg atacctacac tacaggtgct aaccaaatgc aaacggagga tttgaaataa
     3781 tgacacaagc aatccttgaa attaaacacc tcaaaaaatc ctatggacaa aacgaagtgc
     3841 taaaagacat ttcactcact gtccacaagg gagaggtcat ctctatcatc ggaagctctg
     3901 gaagcggaaa atcgaccttc ctacgctcca ttaacctact tgaaacacca actgatggac
     3961 aaatccttta tcatggacaa aacgtcctcg aaaaaggcta tgacctcacg caataccgtg
     4021 aaaagttggg gatggttttc caatccttta acctctttga aaatctcaat gttcttgaaa
     4081 acacaatcgt cgctcagaca actgtcctaa aacgcgaacg cacagaagct gaaaagattg
     4141 ccaaagaaaa cctggaaaag gtcggcatgg gagaacgcta ctggcaagcc aaaccaaaac
     4201 aactctcagg tggtcaaaaa caacgtgtgg ccatcgctcg tgccctctcc atgaatccgg
     4261 acgctattct ctttgatgaa ccaacatcag ctctcgatcc agaaatggtt ggagaagtcc
     4321 tcaaaatcat gcaggacctg gctcaggaag gcttgaccat gattgtcgta acccatgaaa
     4381 tggaatttgc ccgtgatgtc tctcaccgtg ttatctttat ggataagggc gtgatcgctg
     4441 aagaaggtaa accagaagac ctcttcacca atcctaaaga agaccgaaca aaagagttcc
     4501 ttcaacgcta tctcaaataa aaagaaaagg ctgcatcaac cgtgcagtct ttttgctgtc
     4561 ctcaaaatga aaaggcagat tctctatctc tactacttga aggtcaagaa tccgccgtta
     4621 tccaaagatt aatcttcaaa tttttcataa tttttttcat agaaatcaat taggcctagg
     4681 gctgtttcaa atgaaatatt ttttactttt gcacgaccct gcgccagagc aatgatagac
     4741 atttcacgcg tattcgtttc tttagagata cggtagcctg tgattttctt atcacgaacc
     4801 cagccaacaa ctgattctac tttttcaaag tttgacttag ccatgttttt ctcctatttt
     4861 cttctttata atatttaatt gtatacgttt ttactacttt tgtcaataaa aaaaacatat
     4921 attcaacgaa aataattagt tcagaatttt cttacttcct ttttaaatcc gataatatat
     4981 aggttttgct agcctctaca ccataaatat ttgctaataa aaatactgta ttattaccct
     5041 cttaaggtgc gaaattattc aagttcttaa aaaatgcttc tctatttccg taagatagct
     5101 tatttcttcg atttaagaac tgaagatgat agttctaacc tttagaaatc caagccttca
     5161 ctagctcaaa aactcctatc tttcttcctc aataaatcat ctgagagata ggtattcctt
     5221 atgtccttca aattcatcac tcctttggat attgaggtgc tagcctagaa gcagacaccc
     5281 gattatctaa accatcctta ataaagatga caagacagat aagctcagtt aattacttat
     5341 atatcttttt aatatggtat atttgtcaac aaaaagaaat caaatcatac cttatactca
     5401 atgaaaatca aagagcaaac taggaagcta gccgcaagtt gctcaaaaca ctgttttgag
     5461 gttgcagata gagctaacgt ggtttgaaga gattttcgaa gagtattaaa gacagtgtga
     5521 ctatgcttgt caatagatag gaaatcaaaa tgaaggatgg aaatctgagc caaacatcat
     5581 aagtgctata atgaacagaa gtaagaattg cacgataagt tttctaaaac cataggaatc
     5641 gtcccctttc ttcatcttca ttatagcaca tatacatcag ttgtacaaat aatatgatat
     5701 ttttttatta gtcctcagac aagcatatta taaagcgttt cattaccatt taagttaata
     5761 taagctggat caaaaccttc cattctacga atcaaacctg cataatcatg cttatctgct
     5821 aaagcgatcc caattaatac tgggcctgtt cccttgctag ctcgtttgat atactcaaaa
     5881 cgtgtgatat catcatttgg ccccaggata tcatttacaa actcacgcaa agctcctgga
     5941 cgttgtggga aattgaccac aaagtaatgt ttgataccat cataaatcaa ggcacgctct
     6001 tccatttctg gcatacggtt gatatcatta tttcctccag aaatgataca acaaatggtt
     6061 ttccccttaa tatattcagc taaaacctct aaagaggcga tactagccgc tccagcaggt
     6121 tctgcgacta tcccttgctt agagtaaagg tcaatcaagg tttcagaaat caatccctca
     6181 tcgacaccta ccaaagtttg aatatgttga cgagttgctt cataggtcaa ctgacctacc
     6241 ttttgcacag caatcccatc cgcaaattta tcaatttcct tgagttttac tggacctcca
     6301 gcctcaaagg cagctttcat ggaacgcgct ccattcgcct ctactccgat aacctcaatc
     6361 tctggacttg tttccttgat ataggtagaa accccggcaa tgagaccgcc accaccaaca
     6421 ggaaccaaga cagcatcaaa atcaatcgat tcttttcgag cttcttctaa aatctcataa
     6481 gcaactgttc cttgacctgc ttgaacatga gcatcatcaa aaggatcaat aaaggtacga
     6541 ttttcagaga ctgtaaattc ttgagctgct ttggctgagg catcaaaggt atctccaact
     6601 agtttaatag ttacaaaatc cccaccaaaa aagcgaacct gaccaatctt ttgttgtggc
     6661 gtagtaatag gcataaagat agtagcagga attttcattt cattacaagt ataggctact
     6721 ccctgcgcat gatttcccgc agaagcgcag actaccccac gttcacgttc ttccttgctg
     6781 agctgggaaa tggcataata ggcaccacga attttaaagg agcgaacacg ctgggcattt
     6841 tcttttttca aataaatctt agcaccatac ttctccgata aataatgatc gtaatccagt
     6901 ggagtattca caaccacacc gttcaagacc ttgtgagcct tgattatatc ttttgaactt
     6961 aacatataaa acctcttttt ctataaaaaa cagtcactaa tgactgtttt ttagttattc
     7021 atctccgaaa acttcagtaa cactttcatg gtatttatga gccatacgaa tcgaaaactc
     7081 tttaggaagt tcataacgat ttgtggaaat ccaatcatat aaccattcta ccaaactttc
     7141 ttcactatca ttacgatgga agataaaata gtttaaaatt tctttatatt ctacatcatt
     7201 caaatccaac gtgtctacaa attgactacg aggaacaaaa ttagaatcta attttcttag
     7261 ttgatctgtc aattctccca attgtaaatc caactgaaaa aatagttttt gcagttgcct
     7321 atcagtttca tcacatcctg tcttgataga aaacaaattg gtaatattca tatgatttca
     7381 acccctaaat aagtacatct aatatcccac gaatagctga agctaaagtt ttcgcagtcc
     7441 agtcatttaa acccgattct ttcaatccag atgcaataat ttgctctatt tgatataaac
     7501 cgccatctat cgtctcattt attctgcgaa gaggaccttc aatataggat aaagcttctc
     7561 cgaatctaac agctgattta ggtcctaatg atttaccaac tatatttgtt aatgtttttt
     7621 atttctcaaa atccatttcg ctatataacg agcagattta gtcgcgccag ctctctcaaa
     7681 cggagaatga atttcaagac cttcttctct agctatttgt gccaatttga agaattgttc
     7741 aaaggtcata tgcaacctac catcttcaaa attagcatca tcataaatgt taattacagc
     7801 attttcatca tacgaccaat ctgctttatt ttggtctgct agcactatta ccgacggtgt
     7861 aattacatta tacaactaga accaataata acgatgcaat ttttctcata atctttttca
     7921 taaaatcatc tccagcgcta tatatttcta attagttata gattttgaat gcatcatcgt
     7981 cgtttttacc aacgaatggc attgctttac gcaattctgc accaactttt tcaatttcaa
     8041 ggttagctgc ttgttcacgg taagcagtca attttggacg tccagcttta tagtcattta
     8101 caaagtcatt tgcaaattta ccattttgga tgtctgccaa gacagccttc atattttctt
     8161 taacttgttc agtgattaca cgtggacctg atacatagtc accgtattca gcagtgtttg
     8221 aaatagattg acgcattttc ttgaatccac cttcgtagat caagtcaacg atcaatttca
     8281 tttcgtgaag aacttcaaag taagccaatt ctggagcgta acctgcttct gtcaagactt
     8341 cgaaacctgc ttcgataagg gcagtcaaac caccacaaag tacagcttgt tcaccaaaca
     8401 aatcttcttc agtttcttct ttgtaagttg tttcaagaag acctacacga gccgctccaa
     8461 cacctttaca ccagtccata gcaatgtttt tagcatttcc tgttgcatct tggtatactg
     8521 cataaagagc tggaacacca aatccttctt cgtaagtacg acgtaccaag tgtcctggtc
     8581 ctttaggagc acacatgaag acatctacat ccgcgggaac tttgataaat tcaaagtgga
     8641 tgttgaaacc atgggcaaat ccaactgcgt ttccagcttc caagtttgga gcgatttctg
     8701 cttcgtacaa ttcttgttga atttcgtctg gcaccaagat catgataaca tcagccaact
     8761 tagtagcttc tgctactgtg taagtatcaa atccatcttc ttttgcttta tcaaaagatt
     8821 tacctggacg tacacctata ataacgtcac gacctgaatc acgcaagttt tgagcatgcg
     8881 catgcccttg tgaaccataa ccgataacgg cgattttttt accgtcaagt gctgctactt
     8941 taacatcttt ttcatattcc atttgaactg tcatagcttt tctctctttt ctattattta
     9001 ttgcctttta ggctggttta ataaatttaa gttggatttt taatcgcggg taaatccagt
     9061 tgcacccgtt cgagcaatat tgcgaatacc gtatgggcga atgactcgca atagggcttc
     9121 gctcttttct gcatttcccg tcatctgaat ggtaatcgag cttggcgcta cgtctaccac
     9181 tgttgcacgg aaaggttgaa taatcgctaa aatctcagct ctcttctcag ctggcgctga
     9241 catcttaacc aaaatcacct cgcgctccaa atgaggcttg tctgtaatat ctcgaatgcg
     9301 aatcacatca atctgacgat tgagctgttt gatgatttgc tccacttcat catgagaagc
     9361 aacatcaata ataatagtga tacgcgatac attcggatct tctgttgctc caacagagat
     9421 gctttcaata ttaacctgac gacgagatag gacacctgta aagcgattga ggactcctga
     9481 acgattttgt aattttgctg ttaacattct acgcatggaa ctgcaccccc aacatctcat
     9541 gattactctt accagccggt accattggta acacctgttc cttacgagaa atatctacct
     9601 caattagcat aggaacatcc tcagtgatga cttcaaggtc ttgagccaag gtctcaggat
     9661 tgtcaaactt atagttttta ataccataag cctgcgccat caattggaaa tcaggaaggg
     9721 tatcaaagac cgactctgat gttctgcctt catagaagga ttcctgccac tggcgaacca
     9781 ttccaagtga atgattgttc agcataacca ccttgattgg caccttgtaa atattcaaaa
     9841 tagccaactc ctggttggtc atttggaaac caccatcccc aacaaacaag actacttcct
     9901 tatctgggtt agcaatttta gcaccgattg ctgctggaat tccaaagccc attgttccca
     9961 aaccacctga agtcactaac tgacgctcat tttggtaggg ataatactga gctgtccaca
    10021 tttggtgttg accaacgtct gttaccacaa tggcatctcc attcgtcaat tcaccaattc
    10081 gttcaataac tgcttgcggt tgaaccacac gctctttctt gtcataagaa cgaacacgat
    10141 tcttgtcttt agtgactttc tcaatccact tttcagtatt gttgtgaact gttggttctg
    10201 ctagcaacat ttgcaaggcc ttcttagcat ctccaactac aggaatgtct gcactgataa
    10261 tcttgccaat ctcagctggg tcaatatcaa tgtgggcaac cttagcattc ttagcgaaag
    10321 tcttaggatt ccccgtcaaa cggtcatcga aacgagaacc aatactaatc ataaagtccg
    10381 cttccgtcat ggcaatattt gctgcgaatg acccgtgcat gcctcccatt ccaagaaaga
    10441 gtgggtgact cgttgcaatc gttccttgtc ccaaaagact ggttaccact ggaatttgat
    10501 agcgttctgc aaattcattt agttccgtag cagcctcagc ataactaatt ccaccaccag
    10561 ctaacaagac tggcttttta gccttggaca attgcttcaa gattttcttg atttgcatat
    10621 cattcggctc aagagtcggc tgataacttg gtaaattcac ttctggtaaa taaatgaagt
    10681 ctgtttctaa agcagatatg tcttttggta ggtcaattac aactggccct ggacggcctg
    10741 tagttgcgat atggacagct tccgtgatga tacgcggaat atcagctgtc tcacgaactt
    10801 ggtaattgta cttagtgatt ggcatggtaa ttcccacgat gtctgcctcc tgaaaggcat
    10861 ccttcccaat ccctgctcgc gccacctgac ctgtaaagac caaaagggga acgctatcgc
    10921 tcatggcatc cgcaatccct gtaatggcat ttgttgctcc tggtccacta gtgacaacgg
    10981 caacacccaa ctttccagtt gatttggcat aaccttcagc ttcatgcaaa caaccttgct
    11041 catggcgccc tagaatgtgg cgaatgcctt taaaattata tatcgcatca taaaaaggca
    11101 aaaccgcacc accaggataa ccaaagatgg tatcaactcc taaatcacga agtgtttcca
    11161 aaactaggtc cgaccccgtc ttaggagatt ctaaactgat tttctccatt gttccccttt
    11221 ctttcctctt aaaaataact tgttactatc ataccatttt ttcaaaattt ttcaagataa
    11281 aagaagaaat tttctgaatt ttctatttta acgtttattt atgaatatta tttttatttt
    11341 tattaaaaag ataccgattt catttactaa aaaagaaaaa agaactgatt tctcagtcct
    11401 tcattaatct tattccacac taaataggta tgggtaaaca ggttgttgac cttggtgaat
    11461 ctcgacttca acgtcttcga attcttctac gatttcttga gcgatttcat tggcaagttc
    11521 ttcgcttccg tcttcaccga catagaaggt tacgatttca ctgtcttcat ccaacatatg
    11581 tttcaaggtt tcagtcaatg tttggtgcat atcagggttt gacacaagaa tttttccatc
    11641 caccatacct agattatcgt tttcatggat ttctaagcca tcgatcgttg tatcacgcac
    11701 ggctgttgtg acgcttccgc taacgacatc gctaagagca gctgtcatac gctcttggtt
    11761 ttcttcaatg gacttgcttg gatcaaaggc aagaagactt gtcatacctt gaggaagagt
    11821 gcgagcctct accactactg ctggttgctc caaaacttct gccgcagatt gagctgccat
    11881 gaagatgttc ttgttgtttg gcaagaagat gatgttacgg gcattgacct gttcaacagc
    11941 cttgataaag tcttctgttg aagggttcat ggtttgaccg ccttcgataa catagtccac
    12001 gccttgagaa cagaagatat ctgttagacc tttaccagcc accacagcaa ttaaagcata
    12061 ctctttttct tcagccgact tgataacttg agtagcttct ttctcaacct gtgcttcgtg
    12121 ttggttacgc atattgtcaa cttttacctt gaccaagcta ccatatttga gaccttcttg
    12181 cataacaagt cctggatctt ctgtatgaac atggactttg acaatttcat catcgttaac
    12241 aacgaggaga gaatccccaa gctcatccaa gtagttacgg aattcatcgt aatcaaaatc
    12301 tttagcatag gttggacctt gcttaagagc taccatgatt tcagtacagt aaccaaacgt
    12361 gatgtcctca gtcgctacgt gaccagctac agacttatga tgctctacat tgatcatctc
    12421 actcatgttg gcaggagtcg ctacaaagtc ctcagatgca atatattcgc cagtaagggc
    12481 tgaaaggaaa ccttcgtaga tgaagaccaa tccttgacca cctgagtcca caacgccaac
    12541 ttctttcaat actggaagca tgtctggtgt tttagctaga gctgttttag caccttccaa
    12601 ggctgcgcgc atgacttcaa cagtgtcatc tgtttgctca gcttttttct tagcaccgat
    12661 agcagctcca cgagaaactg tcaaaatcgt tccttcaaca ggtttcatca ctgccttata
    12721 ggcaacttcc acacctgatt ggaaggccag agccaagtct tgacctgtta actcgtcttt
    12781 atccttgata gcttgggaaa atccacggaa aagctgagac gtaatcactc ctgagttccc
    12841 acgcgcaccc atcaaaagcc ctttggcaag aatgctcgct acttctccaa ctgtagaagc
    12901 tggcttgtct gcaacttctt tagcaccatt ttcaatggtc attcccatat ttgtcccagt
    12961 atctccatct ggaactggaa agacgtttaa tgaattgaca tattcagctt gcttattcaa
    13021 gcgagttgat gcagcctgca ccatttcttg aaataagcta gtagtaattt ttgacacggt
    13081 tattctccta caactttgat attttgaatg tagacattta cagtctgagc agtaattcca
    13141 agctggtttt ccaagctaaa ggcaacacgc tcttgaatgt tttttgacac ttcactaatc
    13201 tttgttccgt agcttaacac ggtatataca tcaactgcaa tactgccatc ttcggctgcc
    13261 tttacgacga cacctttaga ataattttcc ttacctagca gggcttggaa attatctttg
    13321 agggcatttt tactagccat accgaccaca ccaaaaatct cagttgctgc tccacctacg
    13381 acggttgcaa tcacttcatc tgttagttcg atttgaccat cttttgtatt aatttttaca
    13441 gtcatccttt ttacctcaac tagttgatac tctattttat catatttcag cccaagtgta
    13501 aaagcagaat gatgtatcag cggatattta ctctattttt caaacgatgt tatacccaca
    13561 ataaaagaaa aaagacccta aggtctcctt tgcttttatt attaaacgcg ttcaacttta
    13621 cctgatttca aagcacgagc tgaagcccaa acttttttag gtttaccatc gataagaaca
    13681 gtaacttttt gaaggtttgg ttttacggca cgttttgttt ggttcatcgc gtgtgaacgg
    13741 ttgtttcctg atacagtctt acgacctgta aagtaacata ctttagccat tgtgttttcc
    13801 tcctattaga tctaatatag cggatgtgct agcaccacat accgtactat gttatcacac
    13861 tttcttgttt tttgcaaggg aattggaaga ttttttattt gtgtcttaaa tcaggtcttg
    13921 cgtgacattt tctgctctcc acatgccatc gttgattaac agaacaccag aattaaaatt
    13981 atgtgtataa aaatcatctc taactgcagc taagggtata gccgtcaagt ccaaatccca
    14041 cagctcatct atcgattttc ttacaacaat atctgaatcc aaatacagta cacgagactc
    14101 gcttacatac tttggaataa aatacctaaa aaagccgcat atgaaagtcc ctcaaagggg
    14161 agacgataac ctttcagaat actactgtca atctaaacat tcacaatctc actattcaaa
    14221 gtctctagtc ttttttccat taattggaac cattctcgcg gaaggtcatc attaaaaaca
    14281 taaaacttaa gattataatg atgaacacaa agagatttta ttgttgtttc aactttatcc
    14341 atataagcat tatctgcacc taagacaatc gcttttttct cttctttcac tttttatctc
    14401 atttcttttt attcccatca tatgtttcta cgtaaccatt attttcgcct attcgttcgt
    14461 aaaaccatac cagtggagat tttagatgaa gtcccattac ggtttacaat ttttacatta
    14521 cgacacagag ttttacaaat cgatttcatt tgccaaacgt agttagtgag gcagttagct
    14581 agttcgccaa atagcgacta gcgtccaaca atttggaact ttagttccaa ttgttggtac
    14641 tgagtcacat cttctcctct aactctacgt ctggatactt gtccgcaaac cagcggaggg
    14701 caaagtcatt ttcaaagaga aagactggtt ggtcaaaacg gtctttggct aagatattgc
    14761 gacttgacga catccgttca tccaagtcct caggcttgat ccaacgaacg gtctttttac
    14821 ccattgggct catgaccact tccgcattgt attcgccttc catacggtgt ttaaagactt
    14881 caaactggag ttgaccaaca gcgcctagca tgtactcacc tgtttggtaa ttcttataaa
    14941 gctgaacggc tccttcttgc accaattgct caatcccctt gtggaaggat ttttgcttca
    15001 taacattctt agcagaaact ttcatgaaaa tttcaggagt aaaggttggc agtggttcaa
    15061 attcaaactt gttttttcca accgtcaagg tatccccaac ctgataagta ccggtatcgt
    15121 aaaccccgat aatatcacct gccacggcat tggtcacatt ctcacgactc tccgccataa
    15181 actgggtaac attagatagt ttagccccct taccagtacg agggagattg acactcatgc
    15241 cgcgctcaaa ttcgcctgat acgatacgga caaaggcaat acggtcacgg tgacgaggat
    15301 ccatgttggc ttggatttta aagacaaagc ctgagaaatc cttgtcataa ggatccacaa
    15361 tttcaccgtc tgttttcttg tgaccatgtg gttctggagc aaacttgagg aaggtttcaa
    15421 ggaaggtctg cacaccaaag tttgtcaggg ctgaaccgaa aaagacaggc gtcaattctc
    15481 cagccaaaat agcttcctct gaaaactcat tcccggcttc atttaaaagc tcaatgtcat
    15541 ccttgacttg ctcgtagaaa ggattgctac caaagagttt gtccccgtct tctagactgg
    15601 caaaacgctc atcccctttg taaagctcta aacgttggtt atagaggtca tacaagccct
    15661 caaaggcttt ccccatcccg ataggccagt tcatagggta gctagcaatg cccaagattt
    15721 cttccaattc ttgcaacaga tccaaaggct cacgaccgtc acggtccagc ttgttcataa
    15781 aggtaaagac tggaatgcca cgatgtttca caacctcaaa caatttcttg gtttgagcct
    15841 cgatcccctt ggcagagtcc acgaccatga ccgcagcatc caccgccatc aaggtacgat
    15901 aggtatcttc tgagaagtcc tcgtgccctg gcgtgtctaa gatattcacg cgcttgccgt
    15961 cgtagtcaaa ttgcataaca gatgaagtaa cagaaatccc acgttgcttc tcgatatcca
    16021 tccagtcaga tttagcaaaa gtccctgttt tcttcccttt taccgtacca gcctcacgaa
    16081 tctcaccccc aaagtagagt aactgctcag tgatggttgt tttccccgcg tccgggtggg
    16141 aaataatggc aaaggtacga cgtttcttaa tttcttcttg aatattcata agttctcttt
    16201 ctttgattct ctatttttct tgtttcaata gctgagaatg atttttacat tggattttac
    16261 cattcctttc aacactccat tatatcggat tttagcattt ttttcaattt ctatttcttt
    16321 tcacttcccc ctcccttatt tataggaaaa tatggtaaaa tagaacagac taaaaatcat
    16381 catttcacga aaggatgcaa gatgaaaatt acgcaagaag aggtaacaca cgttgccaat
    16441 ctttcaaaat taagattctc tgaagaagaa actgctgcct ttgcgaccac cttgtctaag
    16501 attgttgaca tggttgaatt gctgggcgaa gttgacacaa ctggtgtcgc acctactacg
    16561 actatggctg accgcaagac tgtactccgc cctgatgtgg tcgaagaagg aacagaccgt
    16621 gatcgcttgt ttaaaaacgt acctgaacaa gacaactact atatcaaggt gccagctatc
    16681 ctagacgatg gaggagatgc ctaatgactt ttaacaataa aactattgaa gagttgcaca
    16741 atctccttgt ctctaaggaa atttctgcaa cagaattgac ccaagcaaca cttgaaaata
    16801 tcaagtctcg tgaggaagcc ctcaattcat ttgtcaccat cgctgaggag caagctcttg
    16861 ttcaagctaa agccattgat gaagctggaa ttgatgctga caatgtcctt tcaggaattc
    16921 cacttgctgt taaggataac atctctacag acggtattct cacaactgct gcctcaaaaa
    16981 tgctctacaa ctatgagcca atctttgatg cgacagctgt tgccaatgca aaaaccaagg
    17041 gcatgattgt cgttggaaag accaacatgg acgaatttgc tatgggtggt tcaggtgaaa
    17101 cttcacacta cggagcaact aaaaacgctt gggaccacag caaggttcct ggtgggtcat
    17161 caagtggttc tgccgcagct gtagcctcag gacaagttcg cttgtcactt ggttctgata
    17221 ctggtggttc catccgccaa cctgctgcct tcaacggaat cgttggtctc aaaccaacct
    17281 acggaacagt ttcacgtttc ggtctcattg cctttggtag ctcattagac cagattggac
    17341 cttttgctcc tactgttaag gaaaatgccc tcttactcaa cgctattgcc agcgaagatg
    17401 ctaaagactc tacttctgct cctgtccgca tcgccgactt tacttcaaaa atcggccaag
    17461 acatcaaggg catgaaaatt gctttgccta aggaatacct aggcgaagga attgatccag
    17521 aggttaagga aacaatctta aacgcggcca aacactttga aaaattgggt gctatcgtcg
    17581 aagaagtcag ccttcctcac tctaaatacg gtgttgccgt ttattacatc atcgcttcat
    17641 cagaagcttc atcaaacttg caacgttttg acggtatccg ttacggctac cgcgcagaag
    17701 atgcgactaa tcttgatgaa atctatgtaa acagccgtag ccaaggtttt ggtgaagaag
    17761 tgaagcgccg tatcatgctg ggtactttca gtctttcatc aggttactac gatgcctact
    17821 acaagaaggc tggacaggtc cgtacactta tcattcaaga tttcgaaaaa gtcttcgcgg
    17881 attatgattt gattttgggt ccaactgctc caagtgttgc ctatgacttg aattctctca
    17941 accatgaccc agttgccatg tacttagccg acctattgac catacctgta aacttggcag
    18001 gactgcctgg aatttcgatt cctgctggat tctctcaagg tctacctgtc ggactccaat
    18061 tgattggtcc caagtactct gaggaaacca tttaccaagc tgctgctgct tttgaagcaa
    18121 caacagacta ccacaaacaa caacccgtga tttttggagg tgacaactaa tgaactttga
    18181 aacagtcatc ggacttgaag tccacgtaga gctcaacacc aattcaaaaa tcttctcacc
    18241 tacttctgcc cacttcggaa atgatcaaaa tgccaacact aacgtgattg actggtcttt
    18301 cccaggagtt ctgccagttc tcaataaagg ggttgttgat gccggtatca aggctgctct
    18361 tgccctcaac atggacatcc acaaaaaaat gcactttgac cgcaagaact acttctaccc
    18421 tgataatccc aaagcctacc aaatttctca gtttgatgag ccaatcggtt ataacggctg
    18481 gattgaagtc gagctagaag acggtacgac caagaaaatt ggtatcgaac gcgcccactt
    18541 agaggaagac gctggtaaaa acacccacgg tacagacggc tactcttacg ttgaccttaa
    18601 ccgccaaggg gtacctttga ttgagattgt atctgaagcc gatatgcgtt cgccagagga
    18661 ggcctatgct tatctgacag cactcaagga agttatccag tatgctggca tttctgacgt
    18721 taagatggag gaaggttcga tgcgtgtgga tgccaacatc tcccttcgtc cttatggtca
    18781 agagaaattc ggtaccaaga ctgaattgaa gaacctcaac tccttctcaa acgttcgcaa
    18841 ggggcttgaa tacgaagtcc aacgccaggc tgaaattctt cgctcaggtg gtcaaatccg
    18901 ccaagaaaca cgccgttacg atgaagcgaa taaagcaacc atcctcatgc gtgtcaagga
    18961 aggggctgct gactaccgct acttcccaga accagaccta cccctctttg aaatttctga
    19021 cgagtggatt gaggaaatgc ggactgagtt gccagagttt ccaaaagaac gtcgtgcgcg
    19081 ttatgtatct gaccttggtt tatcagacta cgatgctagt cagttgactg ctaataaagt
    19141 cacttctgac ttctttgaaa aagctgttgc cctaggtggt gatgccaaac aagtctctaa
    19201 ctggctccaa ggggaagtcg ctcagttctt gaatgctgaa ggtaaaacac tggaacaaat
    19261 cgaattgaca ccagaaaact tggttgaaat gattaccatc atcgaagacg gtactatttc
    19321 atctaagatt gccaagaaag tctttgtcca tctagctaaa aatggcggtg gcgcgcgtga
    19381 atacgtggaa aaagcaggta tggttcaaat ttcagatcca gctatcttga tcccaatcat
    19441 ccaccaagtc tttgccgata acgaagctgc tgttgccgac ttcaagtcag gcaaacgtaa
    19501 cgccgacaag gcctttacag gattccttat gaaggcaacc aaaggccaag ccaacccaca
    19561 agttgccctt aaactacttg cacaggaatt ggcgaagttg aaagaaaact agacagaaca
    19621 aaaccagccc taaggttggt tttttcttct ctaccaactc ccaataacta ttttggcttt
    19681 atttccagag tattttatgg taaaatgaag agtaataata tttattaaag aggtaaaaac
    19741 atgattgaag caagtaaatt aaaagctggt atgacctttg aaacagctga cggcaaattg
    19801 attcgcgttt tggaagctag tcaccacaaa ccaggtaaag gaaacacgat catgcgtatg
    19861 aaattgcgtg atgtccgtac tggttctaca tttgacacaa gctaccgtcc agaggaaaaa
    19921 tttgaacaag ctattatcga gactgtccca gctcaatact tgtacaaaat ggatgacaca
    19981 gcatacttca tgaatacaga aacttacgac caatacgaaa tccctgtagt caatgttgaa
    20041 aacgaattgc tttacatcct tgaaaactct gatgtgaaaa tccaattcta cggaactgaa
    20101 gtgatcggtg tcaccgttcc tactactgtt gagttgacag ttgctgaaac tcaaccatct
    20161 atcaaaggtg ctactgttac aggttctggt aaaccagcaa cgatggaaac tggacttgtc
    20221 gtaaacgttc cagacttcat cgaagcagga caaaaactcg ttatcaacac tgcagaagga
    20281 acttacgttt ctcgtgccta atctctagaa agaggtcatt ctatgggaat tgaagaacaa
    20341 cttggcgaaa tcgttatcgc cccacgtgta cttgaaaaaa tcattgctat cgctactgca
    20401 aaggtagagg gtgttcactc tttttcaaac agatcagtgt ctgataccct ttcaaaactt
    20461 tcactcggcc gtggcattta tcttaaaaac gtggacgaag aactcacagc agatatctat
    20521 ctctaccttg agtacggagt aaaagttcct aaggtagcgg ttgctatcca gaaagctgtc
    20581 aaagatgccg tccgtaatat ggctgatgta gaactcgctg ctatcaatat tcacgttgca
    20641 ggtatcgtcc cagataaaac accaaaacca gaattgaaag atctatttga cgaggacttc
    20701 ctcaatgact agtccactat tagaatctag acgccaactc cgtaaatgcg cttttcaagc
    20761 tctcatgagc cttgagttcg gtacggatgt cgaaactgct tgtcgtttcg cctatactca
    20821 tgatcgtgaa gatacggatg tacaacttcc agcctttttg atagacctcg tttctggtgt
    20881 tcaagctaaa aaggaagaac tagataagca aatcactcag catttaaaag caggttggac
    20941 cattgaacgc ttaacgctcg tggagagaaa cctccttcgc ttgggagtct ttgaaatcac
    21001 ttcatttgac actcctcagc tggttgctgt taatgaagct atcgagcttg caaaggactt
    21061 ctccgatcaa aaatctgccc gttttatcaa tggactgctc agccagtttg taacagaaga
    21121 acaataaaaa gaaaaagtgt ttgatagata tcaaacactt tttctttgcc tcccactatc
    21181 taaaaaaatg ataatagata taattgtaaa caaaaatcca gataggtttt gcatgattga
    21241 gaaagttaaa aaaactatgg cagagaatcg ttaatctcag attgtcggta gaacgataaa
    21301 caagggcaaa aaagaaacca atcagactat aatataataa actaattgga tctctgtgag
    21361 atagtatcaa atggctaatc ccaaagatga tagcagatag gataacatcc aaatagtact
    21421 tggactaggg aaagaaggta ttcataaaat accctctatc aagagtctcc tcaaaaacag
    21481 gaccgatgat tacaggcagg acaaaagata agatagtcga taaaaaggtt ggttgtccat
    21541 ttgaaaaaag cacggtaaaa tactcatcat gaatattcct atgattaatc aaatgagcat
    21601 agcgtgccca aaaattaccg agaatctgat aaaccacata agttgcaaat aagtagaaga
    21661 caaatgacca gttccagctc tttttctcaa agataaagag catctttttc ttttttaacc
    21721 tccaaattaa tagaaggaaa cttcccacta atcccattgt taaaataaga gaatagacat
    21781 cagctcctaa ccctaaaatg atcgtcacat acaatccaat tgtttgtggt aaataggtag
    21841 atagtaaaat aataagcaaa aatattccaa attgtcttag tttttttgtg tttctcatcg
    21901 tacttttttg aaagattacc ctgctcggaa gccgtacttc caagcatcta tataagaatt
    21961 aagtgcccct tgcctcatat agggagcaaa ttctctataa tataaccatc tactatatcc
    22021 atcttcccaa acagcaagac cacctgaagt ttgctccaag tcctcagttg aaagaactgt
    22081 aaatgtattt gtacctgtca ttgcaagtac cttcttaaaa tatagtgatt tgaaataaga
    22141 tgtgaacaac tctatcagga aagtcaaatt aatttataga aatattttag cagccaaggt
    22201 gtactgttat agattcaata cactataaat ttttgtaagc ttacatctac agtatacatc
    22261 ttttttgtct attttatagc ccatctcctc aactgtcaat ttttcaacct gaattgcatt
    22321 tttccataaa aaatgagacc tttctagtct catttagtca ttcttagtat tttctaaatc
    22381 gttgatagcg ttcttccagc aactcttcta gcggtttttg tgaaagtcta gccagctccg
    22441 tttggagttc ttttttgaca ctcttaatca gttctttact agaaagtcct acttcagaaa
    22501 tcaccttatc caccacgtcc atttctaaca gttcatgcga agtgattttc atcagttctg
    22561 ctgcttccat ggcgcgagta ccgtccttcc ataaaatgga agcaaagcct tctggactga
    22621 gaatggcata gatagaattt tccagcatcc agacacggtc cgcgacagct agagccagag
    22681 ccccgcctga accaccttca ccgataataa tggcgataat aggaactttc aggtcactca
    22741 tttccatgag attgcgagcg atagcttccc cttgaccacg ttcttccgct ccgacaccag
    22801 gataagcacc tgctgtgttg ataaaggtca caactggacg gccaaatttc tcagcctgtt
    22861 tcatcaaccg cagtgccttt cggtagcctt ctggatgtgg ttggccaaaa ttccgtttga
    22921 ggttgtcttg caaactcttg cctttttgga taccaaccac tgttacagct tggtctccaa
    22981 gccaaccaat accaccaaca actgcaccat catcacgaaa agaacggtca ccatgtaatt
    23041 ggataaattc atcaaaaatg cctgtcgcaa agtccaaggt tgtcaagcga ctctgctcac
    23101 gcgcttctct gactattttt gcaatattca tctaggactc cctccatgca atctgactag
    23161 gctagcaatc gtatctggta agtctcttct tttgacaata gcatccacaa agccatgttc
    23221 taataggaat tctgcctttt ggaaatcctc aggcaagctt tcacgaaccg tattttcaat
    23281 cacacgacgc ccagcaaaac caaccaagct ctgtggttca gccagaatga tatcgccttc
    23341 catagcgaaa gatgctgtca caccaccagt cgttggatct gtcaaaatgg tcaggtaaaa
    23401 gagaccagca tttgaatggc gtttaaccgc cgcagagatc ttagccatct gcatgagact
    23461 catgattcct tcctgcatac gggctccacc agaggctgtg aataggacaa ctggcaattt
    23521 ttcgacagtc gcatactcaa acaaacgagt gattttttca cctacaaccg tacccataga
    23581 agccatgata aagttagaat ccataatccc aagagccaca gtctgacctt taataagagc
    23641 agttcctgtc acaacggctt catgcagacc tgttttttca cgcatagatg ccagtttctt
    23701 ttggtaacca gggaaatgca agggatcctt gctttcaatc cctgtaaaca attctttgaa
    23761 ggttcccata tcaatcgtca aagccaagcg ttcttgggca gaaatacgaa aggtatagct
    23821 acagtgcgga cagatacgtt cacttcccag atccttctga tagatggtat gcttacagcc
    23881 tggacactgg gaaaataatt catctggaac ctctggctta gcttgaggtt tttccctaac
    23941 cgaacgattg ggattgattc gaatatactt atctttttta ctaaatagag ccattgattc
    24001 cccttttcgg tttaaactct taaagtcatt ttattctttt tcttgatatt taggtaagaa
    24061 ggtttccatc aagaaggaag tatcataatc cccagcaatg acattgcgat ctgaaatgag
    24121 gtcaagctgg aaatctgcat tagtctgcac tccttcaatc tctaattcat agagggcacg
    24181 ttgcattttc atcaaggcgt caaaacgatt ttcgccgtgt actatgattt tggcaatcat
    24241 actatcataa taaggcggaa tggtataacc tggataaact gctgaatcca cgcgcaagcc
    24301 aactccacca cttggcagat agagattagt aatcttacct ggacttggag caaagttaaa
    24361 ggctgggttt tctgcattga tacgacactc gatggcatga ccacgtagga caatatcttc
    24421 ttgcttaaca gacaaaggct gacctgccgc aatgcaaatc tgttccttaa cgatatcaac
    24481 acctgaaaca aactctgtta ctggatgttc tacctgaaca cgagtattca tctccatgaa
    24541 atagaaattg ctacttgctt catcaagaag aaattcaatg gttcctgcat tctcatagcc
    24601 aacaaactct gccgctcgaa cagcagcagc acctatttca tgacgcagcg tttttccgat
    24661 tgcaatcgag ggactttctt ccaaaacctt ttggttattc ctttgaagag aacaatcccg
    24721 ttcacccaag tgaatcacat gtccatgctc atcacctagg atttgaacct caatgtgccg
    24781 agctggatag ataacccgtt ctatgtacat ggcaccattg ccataattgg ccttggcctc
    24841 actagaggca gtttcaaagg cagaaacgag gtcatctggt ttttcaacct tacgaatccc
    24901 tttaccacct ccacctgctg aagccttgag cataacagga tagccaattt tttcagcaac
    24961 aatcaaagct tcttcagagt tatgcacttc tccatctgaa cctggtataa caggcacacc
    25021 tgctttaatc atctgagcac gcgcattgat cttatccccc atcatatcca taacatgacc
    25081 agatggaccg ataaacttga tacctacttc ttcacacatg gtcgcaaatt tggaattttc
    25141 actgagaaat ccaaaaccag ggtgaatagc ttctgcctca gtcaagactg cagctgatag
    25201 aactgcatta atattgagat aagactctgt tgccttgcca ggaccaatac aaactgcttc
    25261 atctgccaaa agcgtatgaa gagcttcctt atcagcagtt gaataaaccg ctaccgtcgc
    25321 aatccccaat tcacgtgccg cacggataat acgaaccgca atttcaccac gattggcaat
    25381 taaaattttt cgaaacatgg agaacctcct tagttcccaa ttgcaaaagt aagggtacca
    25441 ctggctgcaa gcttgccatc cacttcagcc tttgcttcaa ccacagctat ggtgccacga
    25501 cgttttacaa aagtcgctgt cataaccaat tggtcgcctg gtacaacttg cttcttaaac
    25561 ttaaccttgt ccataccagc gtaaaagacc agttttcctt tattttcagg ttttgataac
    25621 tccaacacac cggcagtttg cgccaaggct tccataatca gaacacctgg cataactggg
    25681 tattgaggaa agtggccgtt aaagaaaggc tcgttgatgg tcacattttt gatagcaaca
    25741 atggtatcct cgctcacttc caagacacgg tccactagaa gcataggata acggtgggga
    25801 agggcttctt tgattccttg aatatcgatc atttgatacg taccaatcct ttaccaaact
    25861 caaccatttc ttcgttagag acgagaattt ccgttaccac accatcctta ggagctggga
    25921 tttcattcat gactttcatg gcttcgataa ttaccaatgt ttgacctttt ttgacactat
    25981 caccaactgt aacgaaggca ggtttatctg gtccagcagc caagtaaacc actccaacaa
    26041 gtggactctc tacaagattt ccctcagtag ccacacttgc ttcagctgga gctggaactt
    26101 cttctgctac agtctctgct ggagcagatg taggagctac tggactcggt gttgctagaa
    26161 cgggtgctgg agcgacttga gttgcaactt caggcacagg tctcgcttca ttcttgctaa
    26221 actgcaactc atccgtccca tttttataag aaaattctct caaacttgac tggtcaaatt
    26281 gagtcatcaa gtctttaata tcgtttaaat tcatacttat ctattctccc aacgtttgaa
    26341 agcaagaact gcattgtggc ctccaaaacc aaaagtattt gaaatagcgt atggaatttc
    26401 tttctccaag ccttgtccat aaacgacatt agcttcgata taatctgata cttcacttgt
    26461 cccagctgtc attggtacaa agttatgacg catagcttcg atggtgacga tagcttctac
    26521 tgcacccgca gcccccagca aatgtcctgt aaaagacttg gttgatgata caggtacttc
    26581 cttaccaaga acagctacga tagctccact ttctcctttt tcattggcag gagttgacgt
    26641 tccgtgagca ttgacatagg ctacttgctc tggagaaatc tcagcttctt ccaaggctag
    26701 tttgatggcc ttgacagctc cctgaccttc tggatgtgga gaagtcatgt ggtaggcatc
    26761 acaagtattt ccgtaaccaa ccacttcagc caggatagta gctccacgtt tttcagcgta
    26821 ttcaaggctt tctagaacca acatccctga accttcaccc ataacaaacc cattgcgatc
    26881 cttatcaaat gggatcgaag cacgagttgg atcctctgta gtagagagag ctgttaaggc
    26941 ttggaaacca gcgatggcaa aaggtgtgat agaagcttct gttcctccca ccaacatcac
    27001 atcttggaaa ccaaacttaa tggagcggaa ggcatcccca atcgcatcat ttgatgaaga
    27061 gcaggcagta ttgatagatt tacaaacacc gtttgcacca aaacgcatgg ctacattccc
    27121 agaagccata tttggtaaag cttttggaag agtcattggt ttgacacgtt tgggtccttt
    27181 ttcatgaagg cgaagtacct gatcttcaat ttccttgatt ccaccaatac cagatgcaac
    27241 gataacacca aaacgatccc tattaagagc ctctacatca agattggcat gatttacagc
    27301 ctcttgggct gcatacaagg catataaaga atagttatca aaacggttgg tatctttttt
    27361 tataaagtat ttatcgaacg gaaaatcttg gatttctgcc gcattatgca catcaaagtc
    27421 actatgatca aattttgtaa tgccaccaat gccgattttc ccagttgcta aactattcca
    27481 aaattcttct ggtgtatttc caattggaga tgttactcca taacctgtta ccactactcg
    27541 atttagtttc attcttttca cctctagctt tcgctacata cttaagccac catcaatggc
    27601 aaccacttga ccagttagat aatcttggcc tgctaaaaat actgtcaaat ctgcaacctg
    27661 ctctgcctgc ccaaattctt tcatcggaat ctgagctagt gtagcttcct taatcttatc
    27721 tgataagata gctgtcatat cagactcaat cattcctgga gcaatcacat tgactcgtat
    27781 attccgacta gcgacctcgc gtgccacaga cttggtaaag ccaatcaagc cagccttaga
    27841 agcagcatag ttagcttgac caatattccc catcaaacca acaacactag acatattaat
    27901 gatagcacct tctctggctt tcatcatcgg tttcaagact gattgtgtca tattaaaggc
    27961 accagtcaga ttgaccttga gcactttttc aaaatctgct tctgtcatct tgagcataag
    28021 agtatcttgg gtaatccctg cattgttgac caaaacatct actgaaccca gttctgcaat
    28081 agcttgatca atcatacgct tagcgtctgc aaaatctgat acatctcctg aaatgggaac
    28141 caccttgata ccatagtttg aaaactcagc gagcaattct tctgagattg ccccacgact
    28201 gtttaagaca atgttggctc ctgcttgagc aaacttgtgg gcgatggcaa gaccaattcc
    28261 acgactcgaa cctgtaataa agatattttt atgttctagt ttcatttttt tcctttcaaa
    28321 acttctactt attttagtct atttttctaa aagtgctact aaactcgctt gatcttccac
    28381 atgagctaag tgagcagttt gatcaatttt tttaacaaaa cctgacaaga ctttccccgg
    28441 tccaatctcg ataaagttgc ttatgcctgc ttcttgcatg accccaatac tttcatagaa
    28501 acgaacgggt tccttgacct gacgcgtcaa gagctgagca atgtcctctt tttgcatcac
    28561 agtagcttct gtattgccga ctaggggaca agtaaaatct gaaaaactta cctgagctag
    28621 agtttcagct agtttctggc tagcaggttc aaggagagcg gtgtgaaagg gacctgacac
    28681 cttaagagga atcaagcgtt tggcacctgc ttcttgcaaa agttcaaccg ctcgatcaac
    28741 tgcaaccact tctccagcaa tgacgatttg tgcaggtgtg ttatagttgg ctggagtaac
    28801 cactccaagt tcagaagctt tttgacaggc ttcttcaatg acctctactg gcgtattgag
    28861 aactgctacc atcttgccag agtcagcagg agccgcttct tccatatagg ctccacgctt
    28921 agctaccaag gcaaccgcat cttcaaaatc caaggcgccg cttgccacca aggcagagta
    28981 ttctccaaga gacaaaccag caaccatatc aggctgatag cccttttctt gcaataaacg
    29041 gtagatagca accgaagtcg ctagaatggc tggttgcgta tagcgggtct gattgagttt
    29101 gtcttcttcc gtatcgatga gataacgtaa atcataaccg agcacctgac tcgctcgatc
    29161 aatcgtttct ttgacaaccg gatactgatc atagaaatcc cgtcccatcc ctagatactg
    29221 ggcaccttga ccagcaaata aaaaggctgt tttagtcatt tcttacaact cctgcccagc
    29281 gagaggcttc ttcttgaatt ttcttagcgg ctccgtaata caaatctttt aggatttctt
    29341 cagctgtttc ttctttagaa acaagccctg cgatttgacc tgccatgaca gagccaccat
    29401 ccacatcacc gtgaacaact gctttggcta gggcacctgc tcccatttgt tcaaagattt
    29461 ctaaatcagg atcttcctgc ttaaaggcat ctttttcagc cagttcaaaa tctctagtca
    29521 actgattttt aatagcacga acagcatgac caaagtgctg agctgaaatc gtagtatcaa
    29581 tatcccttgc ttttaaaatt ttctccttgt agtttggatg agcattcgac tcttttgcaa
    29641 ctacaaaccg tgtccccacc tgtacagcct ctgcacctag cataaagcca gccgcagcac
    29701 cttcaccatc cgcaattcct cctgcagcaa taacaggaat agatatagct gtggctacct
    29761 gtcgcaccaa ggtcatggtt gttaatttac cgatatgccc cccagcttcc attccttccg
    29821 caataacagc gtctgcaccg attttttcca tgcgtttagc taaagcgaca ctaggaacaa
    29881 caggaataac gattatccca gcttcatgga aacgttccat atacttgctt ggatttcctg
    29941 ctcctgttgt gacaacttta acaccttctt caataacgag atccacgatg tcttccacaa
    30001 agggagataa gagcatgatg ttgaccccaa agggtttatc agtcaatgat ttgattttat
    30061 caatattggc cttgacaact tctttcgggg catttccccc accgataatt cctaatcctc
    30121 cagccttgga aacagcccct gccaaatcac catcagcaac ccaggccatc cctccttgga
    30181 aaataggata gtcaatcttc aataattctg taatacgcgt tttcatagtg cctccaacct
    30241 tccttgctta cgtaatagtt cgatttcacc ataatttgac agtcaaacta ttacctaaac
    30301 aagagggagt gggtttctcc ctactccttc tactaatatt ctgcttattt tgcttgctct
    30361 tcaacgtaag caaccaagtc accaactgtt ttcaagtcat tttctgcttc gatttggata
    30421 tcaaaagcat cttcgatttc tgagattact tggaacaagt ccaatgaatc tgcgtccaaa
    30481 tcatcaaaag ttgattcaag tgttacttct gatgcgtctt ttccaagttc ttcaacgata
    30541 atttcttgta ctttttcaaa tactgccatg ataggactcc tttaaaataa atagtttttt
    30601 tataacaatg tgttcaccac atgattacct aaattgtaag aatgagcgtg ccccaggtca
    30661 agcctccacc gaagcctgat agaagaacag tctggctacc atctaaagag atgagacctt
    30721 gttctacaca ctctgaaagt aaaatcggga tactggctgc actggtattg ccatattcca
    30781 tcatattggc tggaagtttg gctcggtcaa caccaatttt tctagccatc ttatccaaaa
    30841 tacggtcatt ggcttgatga agtagcagat aatccaagtc tgtcacctct ataggagatt
    30901 catcaatagt ctgcttgata gacttggcta catctcgaat ggcaaaatca aagactgtgc
    30961 gtccatccat cttcaaaaac gaatctgcac tttcttgatc tgaaaatgga gaatgcaaac
    31021 ctgaatgccc ataagttaaa cactcgctgc gacttccatc gctattgaga ctctcagcta
    31081 agaaatgctc ttgctcgcta gcttctaaca agacaccacc agcaccatct ccaaacaaca
    31141 cagctgttga tcgatccgac caatcgactg ccttagagag ggtttcacta ccaatcacca
    31201 agcctttttg aaagcgacca gaagcgataa acttttcagc agttgaaaga gcaaatacaa
    31261 atccactgca agccgcggtt aagtcaaaag caaaggcttt attagcgcca atattagctt
    31321 gaacacgagc agctgtagag ggcatcatcg aatctggagt aatggtagct aggatgataa
    31381 aatccagttc ttttcctgtt attccagctt ttgccatcag tttcttagca acctctgtag
    31441 ccaaatcact ggtagattct gttcttgaaa tatgcctttg tcgtattccc gttcgacttg
    31501 aaatccactc atcattggta tccataatct gagccaagtc gtgatttgta accacttgct
    31561 ctggcacata atgagcaacc tgacttattt ttgcaaaagc cattatttca aatcctccaa
    31621 aaattggtaa agattagtca agcctttacc catgacagca atttcttcct cgctcatgcc
    31681 atcaataatt ttttctacca tggccttgtg gaagcgttta tgcagtctat gaatcaagcg
    31741 acccttcttt gtcaaatgca gatgcaccac acgacgatcc tgttctgacc gaactcgctc
    31801 aatgtagccc ttacgctcta aattgttcaa acttgtcgta acagttccaa gagttaccat
    31861 caactctttt gacacttgac ttggagtcac atctggagcc ttaccgatga catcaatcgt
    31921 atgcatttct ttgatggaga tatccttaaa acgactacct ctcaagttca cttcctcaat
    31981 tacaaggaca ttgttaaata tagatgttaa atattcattg attcgttggt agtccatttt
    32041 tcatatccct ccttcttcaa aaaactttta caatcaaaac atttgacaga aagaattata
    32101 tcaaaattca aagaatgatg caagtatttt ttattttcct gtaaatttag gtcttcttct
    32161 ctccgaatga gctcgcactc cttctttgaa atcctctgtt tgagctaagg atttctgtag
    32221 gttcagttct aaagtagcgt aaccctgcca gtctttaaac tggctctccc aaaccaactt
    32281 cttaatggca gcataggaat tacttgaagc acgtcttaat tttttaagaa gctgttctct
    32341 cgtcttttca agtttttcag cttcagaaac gcggtaaacc aacccccatt ctagggcttt
    32401 ttctgccgtt aaagcctctc ctgtcatagc taattgagca gcacgcgtca caccgatact
    32461 gcggctcaag agatgaattc cccctgcatc tggagccaaa ccaacaccaa caaaggcttg
    32521 gataaactta gccttatccg tcgccaaaca gaaatctgcc gcaacagcca tattcgctgc
    32581 ggcacctgca acagcaccgt caacttccat taaaacaggt ttggctattt gcttgatttt
    32641 ataagaaatc gtattgacca actctgcgat ttttgtcaat gatggaatat catcctcatc
    32701 cactgcccgc ttcatctcta ccaaatctcc cccaactgag aagacctttc cattggcatt
    32761 gattaagata aaatgcacag ctggattttc ttctgccaaa gtcagagctt ctaaaatctc
    32821 ctcacacatg ggaatatgaa aaccatttgc gacctcagga cggttcaagg taaggattgc
    32881 caagtcctct tcaagctgat aaataatgtg ttccatcagg gctccttttt attttataag
    32941 cagtttatac tcttcgaaaa tctctttaaa ccgcgtcagc ttccatctgc aacctcaaaa
    33001 cagtattttg agctgacttc ggctagcttc ctagtttgct ctttgatttt cattgagtgt
    33061 taaattattt cactgtcaaa gtatatcttt tttaggagca gaaagcaaga aaaaatcgac
    33121 tgaaagtgtc tcagccgata agaaaggctc gctttaggct agaaagcatc ttattttctt
    33181 cattgaaaaa agcctttctt tctgctataa tcgtataaaa tacttacttt aggagttctt
    33241 atgaaagttg ttaaatttgg aggtagttct cttgcctctg ctagtcaatt agaaaaagtt
    33301 ttaaacatcg tcaaaagcga ttcagagcgt cgttttgtag tcgtttctgc gcctggtaaa
    33361 cgcaatgctg aagatactaa ggttacggat gccctgatta aatactaccg cgactatgtt
    33421 gcgggtaacg atattagcaa gagccaaagc tggattatcg accgctatgc tgctatggtt
    33481 agtgaattgg gactaaaacc agctgtgcta gaaaaaattt ctaaaagcat tcacgccttg
    33541 gccactcttc ctattgaaga aaatgaattt ctctacgata ctttcctagc agccggtgaa
    33601 aataacaatg ccaaattgat tgctgcctac tttaaccaaa atggtatcga tgcacgctat
    33661 atgcacccta gagaagctgg gattgtggtc acaagtgaac ctggtcacgc tcgcatcatt
    33721 ccatcaagtt atgacaagat tgaagaattg acaaacacca atgaagtcct tgtcattcct
    33781 ggtttctttg gtgtcactaa ggaaaatcaa atctgtactt tctcacgtgg aggttctgat
    33841 attacaggtt ctatcattgc tgctggtgtc aaagctgacc tctatgaaaa ctttacggac
    33901 gttgatggta tctttgcagc ccaccctggt attatccacc aaccacactc gattcctgag
    33961 ttgacctacc gtgaaatgcg cgagttggcc tatgcaggct tctcagtcct tcatgacgag
    34021 gctcttcttc ctgcctaccg tggaaaaatt cctctggtta tcaagaatac caacaaccct
    34081 gaccatccag gtactcgtat cgttctaaaa cacagtaatg atgaatttcc agttgtggga
    34141 attgctggtg actcaggctt tgtcagcatt aacatgtcga aatacctcat gaaccgtgag
    34201 gttggatttg gccgcaaggt tctgcaaatc ctggaagaac ttaacatcgg ttgggaacat
    34261 atgccaacag gtatcgacga tctttctatc attctccgtt ctcgccaact aactcccatc
    34321 aaggaagaag aaatcctgcg tcagttggtt caaaaggcta aagtagatca tgcagaaatc
    34381 gaacacgacc tttctatcat tatgattgtt ggtgaaaaaa tgaagagcca tatcggagtg
    34441 actgctactg cgacacgcgc tctatctgaa aacaaaatca acatccagat gatgtctcaa
    34501 ggttctagtg aagtttctat tatgtttgtt gtcaataaag accaagagaa agcagcaatt
    34561 aaagccctct acaatgcctt ttttggagaa agtaaggaag actaagcatg gctcaatcac
    34621 ttaacaaaac agtactcctc agtacgacag gcacttccta cctctctatc gctgggaaag
    34681 ttgggaaatt ccttgtcgga gatcaggctt tggaatttta cccagatgtc aatgtcgaac
    34741 aatttatcca gattccttgg agccatatca atcagattgg agccaatgtc actggacgca
    34801 aaatcagccg ccacttcgaa gtctttacag acaaaggaaa attcctcttt gcttcaaaag
    34861 actcaggtgc cattctcaaa attgcacgca aaaaactagg caatgacaag gtcgtcaaac
    34921 ttccgaccct gattcagaca attagccaaa aatttaaaaa tctatttgca aaaaagtaga
    34981 aactttagta taatcatagc aacggataag taggttatct tcttctttca gaaagtctgc
    35041 gggtactgcg agcagatagg agggataggt gaaattctac cgttagtaac aattacatac
    35101 acaatcaagt gcacacctgt gaagttggat ggaaccgtgg ccctgccact ccaacgtttt
    35161 gtcaggcgtg cttttttcat aaaggagttc ttatgttaga tatcaaacgt attcgtacag
    35221 attttgaagc tgtcgcagaa aaattagcta cacgtggtgt agatgctgct gtcttgaatg
    35281 aaatgaaaga aatcgatgct aaacgtcgta acatcttggt caaggttgaa actctcaaag
    35341 cagaacgtaa cacagtttct gctgagattg cccaagctaa gcgcaacaag gaaaatacag
    35401 atgacaagat tgctgccatg caaaatctat ctgctgaggt taaagccttg gatgctgaat
    35461 tggcagaaat cgatgctaaa ttgacagaat ttacaacgac tcttccaaat atcccagctg
    35521 acagcgttcc tgttggggct gacgaagacg acaatgtgga agttcgccgt tggggtactc
    35581 cacgcgagtt tgacttcgaa cctaaagctc actgggatct cggtgaagac cttggtatcc
    35641 ttgactggga acgcggtggt aaggtaacag gcgctcgctt cctcttctat aaaggcctcg
    35701 gtgctcgttt ggaacgtgct atctacaact ttatgttgga tgaacatgga aaagaaggct
    35761 atactgaagt catcacacct tacatagtca accatgattc tatgtttggt actggtcagt
    35821 atccaaaatt taaggaagat acttttgaac tcagcgatac caactttgtc ttgattccaa
    35881 ctgctgaagt tcctctgaca aactactacc gtgatgaaat cttagacggc aaagatcttc
    35941 caatctactt cactgccatg agtccgtcat tccgttctga ggctggttct gccggtcgtg
    36001 atacgcgtgg cttgatccgt ttgcaccaat tccacaaggt tgaaatggtc aaatttgcca
    36061 aaccagaaga atcttacgaa gaattggaaa aaatgacagc caacgctgaa aacattcttc
    36121 aaaaactcaa ccttccatac cgtgtcgttg ctctctctac tggagatatg ggcttctcag
    36181 ctacgaagac ttacgacttg gaagtgtgga ttccagcaca aaacaattac cgtgaaatct
    36241 caagctgttc aaacacagaa gatttccaag cccgtcgtgc ccaaatccgt taccgtgatg
    36301 aagcagatgg caaggtgaaa ctccttcata ccttgaacgg ttctggactt gcagttggac
    36361 gtacagtggc tgcaattctt gaaaattacc aaaatgaaga tggttctgtg accatcccag
    36421 aagcacttcg tccatacatg ggtggagctg aagtcatcaa accataaaaa ataaggttta
    36481 gctatttcta gctagacctt ttttcgtaac caaatcagat aagcacctag tacaaagaat
    36541 aaaatagtta ggcatataat ggtttcagcc aataccaggt aatccagaaa tggaagtttc
    36601 aaaattccct gagccatctt gagcgaggtc gctgtgataa tggttgggaa ggtgagggct
    36661 gagaaggctg gttgaaaacc ttgttttaaa atgttgggca gacgagttaa aacaaagaaa
    36721 aagaaggatt gagaagccaa aatcatgaca atcaagaccc aagtcggcag gctggttcct
    36781 cctactcgaa ctagagaagc caagagtaga gagaaaggag cacagtagat tccttcttgt
    36841 ccaagcaagg ctagtgggag tggatgtttc tttaaatcgc tataaataag gggatagaga
    36901 tagaaggtca agagaaaacc aaaactcaag gtcgcatagg caatttcgat aatacctacc
    36961 agaggatagg tcaaggcagc cactgctatc cccacataga gaaccgtcca gcttggagtg
    37021 gcatgaaccc tccgctctgg acaagcaaac ttgatggtaa aaccagcaat caaggtcaaa
    37081 tccaagagaa atgaaaacca ccaaatccct tgtgctacca aaggaagata agagaatacg
    37141 cgaaagacat aggtcgataa aatcatccca gccataggaa aggttgccat tcctgacaaa
    37201 agagggggct tggtcaattc ttgcttggtt tctttccaat taaagagatg cagaattaga
    37261 aagtaaatcc ataaaaccaa accagtcaga ctaaaaagat gggatagaac tggcaacata
    37321 tctaaaataa gatttccagc tcctgccaaa cctagcaaac aacctgaaaa tactaagggg
    37381 agttttttca tcctaacctc caataatcat gttagtttca gtataacata aaagcgctta
    37441 aatgaggatt taaaaaaacg aagtccgatt atttcagact tcattttact cagatatgaa
    37501 ttaggcataa ggttgcaatt ctggattaat tggtgtatta gctaagttgt tggcatagtt
    37561 acagaggatt gctaggctga caccgaaaac cacatccaag gcattttgtt gagtgtagcc
    37621 agcttctaaa aactcagaca aggcttcatc tcctacacga cccttggtat tgataactgc
    37681 caaggtaaac ttagctaggg tatccaattt aggatctgtt tcaattggag tacgattgcg
    37741 aagagcttga atcaagtcat cattcatctg gatttgtttg atggaaaagg ctgtgtgacc
    37801 tgcgacacag aaggcacaac cattggtcac ggctgccgtg atttgcacca cttcacgctc
    37861 aacgggtgtc aggctgttgc gacggtggat agatgagaca atttggtagg cttctaaaac
    37921 agtcggggca ttggccaaga gaccgattag gttgggaata tagccattgt tgtctttttc
    37981 tactgtttca agaatttctt tcacttctgc tggtgctgac tctactgtat ggatagtaaa
    38041 tgttgtcata agatacctct tttcttatta ttgacactaa tattattgga aaatcttata
    38101 aaatcctgat tcctaagttt atctaagata aagctttatt ctctcataag attttcgttg
    38161 ttatattagt ttatcacact tccaatcact tgcataatat atattatata tcaggctgat
    38221 aaaaattatt tataggcaaa aaaatcacac gagctgtgtg attccattat ttgtcaaaat
    38281 actttttagt ttcagcaata acgactggcg acaagaccaa gagggcaatc aagtttggca
    38341 gagccatcaa ggcgttaacg atatctgcga taatccagac catatccaac tcgataaatc
    38401 ctcctaacaa gaccatgagc acaaaaacca cacggtagag ccagataaag cgaaccccaa
    38461 agaggaactc aaaacagcgt tctccgtaat agttccaacc tagaatcgtt gtaaaggcaa
    38521 aaagtacaag gaagatggtc aagagggcag gcccaaagtg tgaaaagact gttgagaaag
    38581 ctgactgagt caaggcaacc ccattcaagt caccactcca aactccagtt accaagatgg
    38641 tcaaaccagt tagagtacaa atgatgaggg tatcaataaa ggttcctgtc atggaaatca
    38701 aaccttgctc tactggttca tttgtcttgg cagctgcagc tgcaatagga gcagaaccca
    38761 gaccagattc gtttgagaac acaccacgcg ccacaccatt ttgaatagcc atccgaacgc
    38821 tagcaccagc aaatccacct accgcagcaa ggggactaaa agctgaggta aagactaaag
    38881 cgattgtgcc agggattttt ccgatattaa agaaaataac tataagagtt cctaagatat
    38941 aaatgatggt cataaaagga acaacagtag ttgaaacctt agaaatagac ttgagtccac
    39001 caaagactgc aatcgctaca aagacagaca agacgagagc tgtgatgact ggcgaaatcg
    39061 tcgttgtatt ttggatagat tctgtaatcg agttgacttg ggtgaaggtt ccgattccca
    39121 agagagcaac caatactcct gctactgcaa acaaaacagc aagtggtcgc cacttttctc
    39181 ccatccctag aaggatatag tgcatgggac ctcccgctac tgcaccatgg tcgtccttgg
    39241 tgcggtattt gatggccaag agtccttccg catacttggt agccattcca aagaaagccg
    39301 ccatccacat ccaaaataga gctcctggtc caccaacctt gatagccgtc gcaactccta
    39361 tgatatttcc tgttccaaca gttgatgcca aggctgtaca cagagctgca aaactggata
    39421 catcaccatg tcccttatcc tggataaaaa taagctgaaa ggccttgggc agacgcaaaa
    39481 cctgcaagag tcctagccgc atggttaggt aaatccctgt tccgaccaat aaaatcaaga
    39541 ggggcggtcc ccaagcaaaa tcatcgattg atttaagcaa ttctaacatt tccttctcct
    39601 atcgtttcaa ccccaaaaga aagagcacat gcaagataca tgtactctgg aatgcttaga
    39661 taaatgctaa aaagcggtct atcctagctc tgtcctttta cctgagagtt tgagcagttg
    39721 cctgccttgc cccttcggtg cctttacggt ctctccagag ttccgtccat ttacagtcat
    39781 ggaaaatcaa acgattcccc acttctatta aacttcattc ggtgttggta tttaattgat
    39841 tctaatttta caaaaaatgt tggcttttgt caatgtgttt attagtaaaa attagttcaa
    39901 cagtttttac tttataaagt ccagaatact gctatccttt aaaagtgaca atagtcgcac
    39961 cactgcctcc agcattttgt ggggcatagc cgaaactctt gacatgtttg tttctttgca
    40021 agtatttggt aactccttca cggatgactc ctgttccgat accatggatg atatcaactt
    40081 gagccatatt gttaagcaag gcttggtcga tgaaggtatc tagctcattc atggcttctt
    40141 catagcgctt gcctcgaaga tccagtctag cttgaggtcc tcgcccagaa gttcgtttca
    40201 caacattgac ctgtttcttc ttgactggtt tttcttgctg ggcttgaaca agatcaaact
    40261 ctttctcttc caaggtcatc ttaatcaagc caacttgggc ttcccagcgg ccgtccttga
    40321 gttgactggt caaggtacca cgctgaccat aactgagaac cacgatatca tctcccacct
    40381 ttggagctcg ttttttcttg gccttttgaa ggaccttgtt tttagacaag tccacttttt
    40441 caggagccaa ttttttcaac ttggccttgg cttcaatgat ttcgtggggc ttgagttggg
    40501 atttactgtg gagatttttg agaatctggt cactttcact tagggccata tccacaatct
    40561 cagcagcctg ttcacgcgcc ttgttaagct cggtttcctt ttcacgatta agctcgttgt
    40621 agagtttttt tagcgcacgg ttcatcttga gattttcttg ctccacctca cggatattgt
    40681 ccaaacgttt gcggctttcc agcgtctgct cttctaattg ctcaatgata cgattgacgt
    40741 cattgtcctg atcgatctgc tgactggcat ctcctacgat aacttcagat aggcctagac
    40801 gtttggcaat ttcaaaggca ttacttcggc caggaacacc ctgcataaag cgataggttg
    40861 ggcgaagagt tgcagtatca aactccatac tggcattttg cacaaaggct gtctcaatac
    40921 cgtaggcctt gagttctgga tagtgggtcg tcgccatggt cttgatttga cgcaggcgaa
    40981 ggtcctccag aatagccatg gcaagggctg ctccctcttg gggatcagta ccagccccca
    41041 actcatccaa aagtaagagt gaatgttggt tgaccttgcc aagaatatcc acgatattgg
    41101 tcatatggct agagaaggta gacaagctct gctcaataga ctgctcatct ccaatatcag
    41161 caaaaatttc ttcaaaaata ccaacacaac ttcccttgtc tgctaaaatc ggtaatcctg
    41221 actgggccat gacctgtgtc aagcccagag ttttgagcat gatggtcttc ccacctgtat
    41281 tgggacctgt aatgacaata gctgttaaat cttgaccaaa atagacatca tttgcgacgg
    41341 catttttgac caaaggatgg cagacatgga gcagttgaat ctcttgattt tctgacagct
    41401 gaggcacgac tgcttgtctt tcttggataa atcgaacctt tgcacgaatc aagtccagat
    41461 gaccgataat ccaagcgtca ttagcaatct cagtcgcatg agggcggaca cgctcagaaa
    41521 tttcttggag aatgcgaagc atttcatagc gctcatctgc tcgcagactg gcaatttctt
    41581 cgctcagttt gactacctca cgtggttcga tatagacggt gtttccacta gcagaaatat
    41641 catgaacgac acctgcaatc ttattgcggt aggtgttttt gactggtaaa acctgacggc
    41701 catttctgct agcaacaatt ccttccgtca acatctgcgc tttttgcttg agtaagtctt
    41761 gtaaaacatc gcgtacctga ctctcgctat catgtatttt tcgacggatt cgcgccaatt
    41821 cttcactggc aaaattttca atgaaacccg catcattaaa ggcctgaaga tttccttgta
    41881 attgcggaaa atcatgtaat ttctcaaacc aaagggctaa ttcttccaag ctgacatttt
    41941 ccagattggc ataaaaactt tgaagttctc ggctggcaag aagcacgcgt ttcaagagta
    42001 ggaactcctc gatattgaga tccgctccca tctccaacct cttgcagact cctgcaattt
    42061 ccttagttga gagaatagta aaatgcggtt gctcgacgaa aagagcctgc atttctttca
    42121 tctcagcaaa agcctgtttg attttatctg ctttggcagt cggagccagc tgtctcaatt
    42181 gctccaagcc ctgctcggtc aacaaatgag gctcaaacaa ggccttgacc ttatcgaact
    42241 ctaatgtttc taatattttc ttattcatct ttatttcctt gtctttgaat gtctaggtgt
    42301 ggtagctttt tacattctga tagattcgag tcaaatctgt aaacaaaggg ctaggaaaac
    42361 tcctgccctt tttatccgat taaatttgtc acccagattt gtttgagcca actggttgtt
    42421 atcggtatgc tctggatgat gtgttttgcg acgatactct tttcaagagg attttgtata
    42481 actgccatgg ggatggtcgc caagattgtc aaggccattt gcaagacaaa taaggtcacc
    42541 aacatggaca agatacctgc tgaaacttgg aacaacttac cacccagttt tttgctagga
    42601 atcaagtgta agagaagacc aagcaaacga ccaatgctat agacaatccc aaatacaagc
    42661 aagtagccga tacctgcata aaagacctta tccagctgaa agagttgatc cgatgggaaa
    42721 aagaaagtcc cctgaccttc ctgcgaattt gcataaggga gcaataaatg gaattgctct
    42781 ccaagcccct tataaaactg gccagccata aaagccgatg ccatggctga aatcaggtaa
    42841 taaacctgta agagcaggcc tctccgatag ccgatataaa atccccaaac caagatcaat
    42901 agaagaagga atgaaatcat aaggaatcct caatcttgct ctgttcttgc ttacaagtca
    42961 caagcttgtg acggagttct tctagctctt gctccttatc gtcaaattca atctcacggc
    43021 tgagctgagt tgataaacag ttgactgcca acaaaagagc gattgtttca tcatctgcgc
    43081 taggcatttg ttctttaatt gcttggtatt tttctgtcgc aaccttagcg atttcctcca
    43141 taaaaaggtt atcatgttcg cttgtcaagg ttaacgattt tttcccgaat gtaaatttga
    43201 atcgatttag atttgccata aaattcacct cacgatatta taccaaaatt cgctaatttt
    43261 gtcagttttt acaaatttta ctgcttttgt ggtacaatag aaactatggc aagtatcaca
    43321 ctcacaccaa gcgaaaagga tattcaggct tttcttgaac actatcaaac cagtctggct
    43381 cctagcaaga atccctatat ccgctacttt ttgaaactac ctcaagcaac ggtttctatc
    43441 tatacttctg gaaaaatctt gcttcagggt gaaggggctg aaaaatacgc cagtttcttt
    43501 ggctatcaag ctgtagagca aaccagcgga caaaatcttc ctttgattgg gacagatgag
    43561 gtgggaaatg gttcctactt tggtgggctt gcagttgtgg ctgcctttgt cacacctgac
    43621 cagcacgact ttttacgaaa actcggtgtg ggggattcta agactctgac cgaccaaaag
    43681 atccgtcaga ttgctcctat tctcaaggaa aaaatccagc accaggcact ccttctctca
    43741 cccagcaagt acaacgaggt catcggagac cgctacaatg ctgtttcggt taaggttgcc
    43801 ctccataatc aggctatcta tctcctcctt caaaaaggtg ttcagcctga gaaaattgtg
    43861 attgatgcct ttaccagtgc taaaaattat gacaagtact tggcacaaga gaccaatcgt
    43921 ttcagcaatc ctatcagctt agaagaaaag gctgagggca aatacttggc tgtcgcagtt
    43981 tcttctgtca ttgcgcgtga tctctttctg gaaaatcttg aaaatttggg acgagaactg
    44041 ggttatcagc tcccaagtgg agctggaacg gcttctgaca aggtggctag ccagattttg
    44101 caagcctatg gtatgcaggg actcagcttc tgcgccaaat tgcactttaa aaacactgaa
    44161 aaagcgaaaa aacgcttaga aaggtaagtt atgaattcat ttaaaaattt cttaaaagag
    44221 tggggattgt tcctcctaat tctgtcatta ctagctttaa gtcgtatctt tttttggagc
    44281 aatgttcgcg tagaaggaca ttccatggat ccgaccctag cggatggcga aattctcttc
    44341 gttgtaaaac accttcctat tgaccgtttt gatatcgtgg ttgcccatga ggaagatggc
    44401 aataaggaca tcgtcaagcg cgtgattgga atgcctggcg acaccattcg ttacgaaaat
    44461 gataaacttt acatcaatga caaagaaacg gacgagcctt atctagcaga ctatatcaaa
    44521 cgcttcaagg atgacaaact ccaaagcact tactcaggca agggctttga aggaaataaa
    44581 ggaactttct ttagaagtat cgctcaaaaa gcccaagcct tcacagttga tgtcaactac
    44641 aacaccaact ttagctttac tgttccagaa ggagaatacc ttctcctcgg agatgaccgc
    44701 ttggtttcga gcgacagccg ccacgtaggt accttcaaag caaaagatat cacaggggaa
    44761 gctaaattcc gcttctggcc aatcacccgt atcggaacat tttaagagac ctaagaggcc
    44821 gagaatcacc aatctcagcc tcttcttcta tcgtgagaag tgattgttta ttgacaaata
    44881 ctcaatgaaa atcaaagaac aaactaggaa gctagccgta ggctgcttaa aacagtgttt
    44941 tgaggttgtg gatagaactg acgaagtcag ctcaaaatac tgttttgagg ttgcagatgg
    45001 aagctgacgt ggtttgaaga tattttcgaa gagtataaaa taaaaacaat cccaactctc
    45061 acctattcat gcaaaggaat tttatggaag tttatttttc aggaaccatt gaacggatta
    45121 tttttgaaaa tcccagcaat ttttatcgca tcctcctcct agaaatcgac gatacggacg
    45181 cagaggattt tgatgacttt gaaatcattg tcacaggaac catggctgat gtaattgagg
    45241 gcgaagacta tactttttgg gggcaaattg tccagcactc caagtatgga gaacaactgc
    45301 aaatcagtcg ttatgatcgc gcaaaaccaa ctagtaaggg cttggtcaag tacttttcaa
    45361 gtagccattt caaggggatt ggtctcaaga cagctcagaa aatcgtggat acctatggcg
    45421 aaaataccat tgacgaaatt ttgcaacacc cagaaaagtt agaaggcatc gcaggactct
    45481 ctgccaaaaa tcgcgaggct ttcgtctcca ctctccgtct caactacgga acagagatga
    45541 ttttggccaa actagccaac tacggcattc ccaacaaact agcctttcag attcaagact
    45601 tttacaagga agaaaccctt gatgtggttg aaaattatcc ctaccaactg gttgaggata
    45661 tcaagggttt gggctttacc attgctgacc aactagctga ggaactaggc atcgaaagtc
    45721 aggctcctga acgcttccgc gccggtctag ttcacagtct ttttcagacc tgtatggaaa
    45781 caggggacac ctatgttgaa gcacgggatt tgctggaaca aacccttact ctccttgagt
    45841 cttcccgtcc cgtggaacta gaccccagcc aagttgccca agagctctcc tacctgatcg
    45901 aagaagacaa ggttcagcag attgatacca agatctttga caacagcctc tttttcgctg
    45961 aggaaggtat ccgcagtcac ttgattcgta tccttgaaaa aggaaaacag aagagccaag
    46021 atttagaaac cattcaaaag catatcacta ctgtcgagca agaactgggg attgagtatg
    46081 ataacattca aaaacaagct atttgtgacg ctatccagaa caaggtcttt atcctgacag
    46141 gtgggcctgg tactggtaag acaactgtta tcaatgggat catcgctgtt tacgccctgt
    46201 tagagggact tgacctcagg aagaaaagca atctgcccat tcttcttgct gctccaactg
    46261 gtcgagctgc tcgtcgcatg aatgaattga caggtttgcc tagcgcgacc atacatcgcc
    46321 acttgggaat gacaggtgac gatgatacca gtcatctgga agattaccta gatgctgact
    46381 ttatcatcgt ggatgaattc tctatggtag atacttggct ggccaatcaa ctcttctcca
    46441 atatctcttc taacagtaag atcctcatcg taggtgacag tgatcagcta ccttctgtca
    46501 gtcctggaca ggttctagcg gatctgcttc atattccttt gattcctcag actcgcttgg
    46561 aaaaaattta tcgacaaagc aaagaatcaa ccatcgtcac cctagctagt cagattcgac
    46621 agggcatctt gccagctgat ttcacccaaa aaaaagctga ccgttcctac tttgaaattg
    46681 ctagtggcca tattcctgcc accattgaaa aaatcttagg tgtcgccctc agaaatggta
    46741 ttcctgcccg tgatatccaa gttctggctc ctatgtaccg agggacggca gggattgatg
    46801 ctatcaatca gctcatgcaa gacctgctca atcccccaca aaaagatcaa ctcagttttg
    46861 aagctcctca gtgccactat cgtaagagag acaaggtcat tcatttggtt aacgatgctg
    46921 aaatcaatgt ctttaatggg gatttaggag ctatcacaga cctgattcct ggtaaataca
    46981 ccgaatcgaa acaagacgag attgtcattg attttgatgg taatgaagtc tcttaccccc
    47041 gtaacgaatg gtacaagatt cgcttggcct atgccatgag tattcataag tctcagggaa
    47101 gtgagttccc agttgtcatc ctaccgatta ctagtgctag ccgacgtatg ctggagcgaa
    47161 atctcatcta cacagccatt acacgtgcca aaagcaaact catcttacta ggcgaattac
    47221 aagccttcga ctatgctacc caacacatcg gaactgcccg aaaaacctat ctgattgaac
    47281 gcttcagtga tctactggag aatgttgaag aaaagcaaca agctgtctct gaaacagtca
    47341 catcaagtgc ctctgaacaa tcctacatcc taaccgaaga aaactgggac agcattccag
    47401 ccatgattgg gattacagac acagacctca aagagatttt tggaaaatag tacatcagaa
    47461 aacccaccaa ttcaggtggg ttttctgttt attaagatta ttttactgtt gctgtgcttg
    47521 tgatcaattc aacagctttt ttgatagtga tatcatgttt caacatgtca gctgaaagca
    47581 agttttgaac ttgtgcaact tccatgttgt agtctgctgc caattgctca acttcttttt
    47641 ggatttcttc ttctgaagca tcaaatcctt cagctttggc aactgcttcg ataacaaggt
    47701 tagtcttagt acgtgactca gcttctgctt ggtattggtt gtgaaggtct tcttgagtag
    47761 ttccagtgat ttggaagtac atgtcagggt tgatcccttg acgttgcaag ttcccaagga
    47821 attcatttac tgaacggtga acttcttcat ggatcatttc ttctggaagt tctacgattt
    47881 cagcgttttc tacagctgta tcaattgctg caccttcaac tgcatctttg taagcttctt
    47941 ctttagcagc agccaattct ttgcggtatt tttctttcaa gtcagcaagt gtttcaactt
    48001 cttcatcaat gtcttttgca agttcatcgt caagagctgg aacttcttta gcttttactt
    48061 cgtggatagt tgtcacgaat ttagcttctt tacctgcaag gtcttctgct tggtagtctt
    48121 ctgggaatgt tacgataaca tcaacggttt cgccagctga gtgacctacc aattggtctt
    48181 cgaaaccagg gatgaattga cctgaaccaa gtccaagtga gaagttttca ccttttccac
    48241 cgtcaaattc aacaccgtcg atagaaccaa cgaagtcgat cacaacagtg tcgccgtttt
    48301 cagcagcagc ttccttgata accaattcag ccagattgtt gcgttcgcgt tcgatacgct
    48361 cttcaacatc agcgtcagtt acttcttttt ctacatcaac tgatacttca aggtttttgt
    48421 agtcacccaa ttttacttca ggttttgtaa cgacttcagc agcgataacc cagtcttgac
    48481 ctttttccat tgaagttacg tcaatttttg gttgggcaac cacttcaaga ccagcttctt
    48541 ttacagctgc ttcataagcg tttggcaaaa gagcgttcat aacgtcttgg taaagtgatt
    48601 cttcaccaaa ttttttgtcg aagataggac gtggaaggtg acctttacgg aaacctggaa
    48661 cattaagaga tttcttcact gacttgaaga cacggtccaa ttctggtttg atttggtctt
    48721 gagagatagt gaaagtcaag acaccacggt ttgtttcttt gttttcaaat gatacagaca
    48781 ttctgtcatt tctccttaaa attttttaaa tacagtctat tataacattt tctataaata
    48841 aaatctagac taatgcagcc aattatagac aacaagcctt tttcctaact aaaacactca
    48901 taaaatatag acaattttag actactttgg atatcttttg gttagtcatt ttccaaaact
    48961 aatttatcta atttttcagt tatatagtag
//
LOCUS       DAVAGB010000012        48156 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVAGB010000012 DAVAGB010000000
VERSION     DAVAGB010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48156
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.012"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(7..303)
                     /locus_tag="VQO19_000743"
     CDS             complement(7..303)
                     /locus_tag="VQO19_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349037.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(287..2446)
                     /gene="pfbA"
                     /locus_tag="VQO19_000744"
     CDS             complement(287..2446)
                     /gene="pfbA"
                     /locus_tag="VQO19_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HET1349038.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNN
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRENGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3577..4803)
                     /locus_tag="VQO19_000745"
     CDS             complement(3577..4803)
                     /locus_tag="VQO19_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HET1349039.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWRANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4846..5538)
                     /locus_tag="VQO19_000746"
     CDS             complement(4846..5538)
                     /locus_tag="VQO19_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET1349040.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMHYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(5711..7462)
                     /locus_tag="VQO19_000747"
     CDS             complement(5711..7462)
                     /locus_tag="VQO19_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1349041.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQETSDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGLSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMADTL"
     gene            complement(7452..9197)
                     /locus_tag="VQO19_000748"
     CDS             complement(7452..9197)
                     /locus_tag="VQO19_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET1349042.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLVFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     CLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9403..9699)
                     /locus_tag="VQO19_000749"
     CDS             complement(9403..9699)
                     /locus_tag="VQO19_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HET1349043.1"
                     /translation="MSASDVALKLRGQGIFQMKQVKRAVQEQNGQLIVVQMGDENSKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(9852..10307)
                     /locus_tag="VQO19_000750"
                     /pseudo
     CDS             complement(9852..10307)
                     /locus_tag="VQO19_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10440..11267
                     /gene="xth"
                     /locus_tag="VQO19_000751"
     CDS             10440..11267
                     /gene="xth"
                     /locus_tag="VQO19_000751"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HET1349044.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTVTFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11279..11422
                     /locus_tag="VQO19_000752"
     CDS             11279..11422
                     /locus_tag="VQO19_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET1349045.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCDLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            11422..11661
                     /locus_tag="VQO19_000753"
     CDS             11422..11661
                     /locus_tag="VQO19_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET1349046.1"
                     /translation="MLEEGTKDQLAELTYLFGRGVNLSFGIKDVSKLYQRVMKANYPI
                     YRPLTKRKFRVSDHYIYPHEFAVLDPDSYFLRFSE"
     regulatory      12045..12140
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12540..13121
                     /locus_tag="VQO19_000754"
     CDS             12540..13121
                     /locus_tag="VQO19_000754"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HET1349047.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13121..14383
                     /locus_tag="VQO19_000755"
     CDS             13121..14383
                     /locus_tag="VQO19_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HET1349048.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIAMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14470..15336)
                     /locus_tag="VQO19_000756"
     CDS             complement(14470..15336)
                     /locus_tag="VQO19_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnII"
                     /protein_id="HET1349049.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEETKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(15323..16093)
                     /locus_tag="VQO19_000757"
     CDS             complement(15323..16093)
                     /locus_tag="VQO19_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET1349050.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(16119..16973)
                     /locus_tag="VQO19_000758"
     CDS             complement(16119..16973)
                     /locus_tag="VQO19_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HET1349051.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELIPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYINNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(17130..17534)
                     /locus_tag="VQO19_000759"
     CDS             complement(17130..17534)
                     /locus_tag="VQO19_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HET1349052.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGRRSEDRQVRI"
     gene            complement(17604..19085)
                     /locus_tag="VQO19_000760"
     CDS             complement(17604..19085)
                     /locus_tag="VQO19_000760"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HET1349053.1"
                     /translation="MILVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARTNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQAAFMRFVEQVGISLD"
     gene            complement(19104..20282)
                     /locus_tag="VQO19_000761"
     CDS             complement(19104..20282)
                     /locus_tag="VQO19_000761"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HET1349054.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            20447..21454
                     /gene="galR"
                     /locus_tag="VQO19_000762"
     CDS             20447..21454
                     /gene="galR"
                     /locus_tag="VQO19_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HET1349055.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(21500..22537)
                     /locus_tag="VQO19_000763"
     CDS             complement(21500..22537)
                     /locus_tag="VQO19_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET1349056.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAVTTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLQSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(22538..22891)
                     /locus_tag="VQO19_000764"
     CDS             complement(22538..22891)
                     /locus_tag="VQO19_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET1349057.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(23135..24025)
                     /locus_tag="VQO19_000765"
     CDS             complement(23135..24025)
                     /locus_tag="VQO19_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HET1349058.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDV
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     VSLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            24158..24694
                     /locus_tag="VQO19_000766"
     CDS             24158..24694
                     /locus_tag="VQO19_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET1349059.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIINLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(24861..25667)
                     /locus_tag="VQO19_000767"
     CDS             complement(24861..25667)
                     /locus_tag="VQO19_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HET1349060.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(26012..27532)
                     /locus_tag="VQO19_000768"
     CDS             complement(26012..27532)
                     /locus_tag="VQO19_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HET1349061.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALMAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(27525..28253)
                     /locus_tag="VQO19_000769"
     CDS             complement(27525..28253)
                     /locus_tag="VQO19_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1349062.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            complement(28268..29032)
                     /locus_tag="VQO19_000770"
     CDS             complement(28268..29032)
                     /locus_tag="VQO19_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HET1349063.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(29036..29479)
                     /locus_tag="VQO19_000771"
     CDS             complement(29036..29479)
                     /locus_tag="VQO19_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET1349064.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(30161..30457)
                     /locus_tag="VQO19_000772"
     CDS             complement(30161..30457)
                     /locus_tag="VQO19_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET1349065.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(30479..31543)
                     /gene="pepA"
                     /locus_tag="VQO19_000773"
     CDS             complement(30479..31543)
                     /gene="pepA"
                     /locus_tag="VQO19_000773"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HET1349066.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            31943..32644
                     /locus_tag="VQO19_000774"
     CDS             31943..32644
                     /locus_tag="VQO19_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HET1349067.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLKENQIDAVLHYAGEIVVSESIENPSKYFTANVAGRNQV
                     LKVLSEVGTQKIMFSSTASLYGNNCIDKPATEDTLIDPVNPYTETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            33067..34026
                     /locus_tag="VQO19_000775"
     CDS             33067..34026
                     /locus_tag="VQO19_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET1349068.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKCYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            34016..34972
                     /locus_tag="VQO19_000776"
     CDS             34016..34972
                     /locus_tag="VQO19_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HET1349069.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            34969..35721
                     /locus_tag="VQO19_000777"
     CDS             34969..35721
                     /locus_tag="VQO19_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1349070.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGS
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            35817..36782
                     /locus_tag="VQO19_000778"
     CDS             35817..36782
                     /locus_tag="VQO19_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HET1349071.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTTFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(37007..37249)
                     /gene="yidD"
                     /locus_tag="VQO19_000779"
     CDS             complement(37007..37249)
                     /gene="yidD"
                     /locus_tag="VQO19_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HET1349072.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(37249..37971)
                     /locus_tag="VQO19_000780"
     CDS             complement(37249..37971)
                     /locus_tag="VQO19_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET1349073.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(37958..38527)
                     /locus_tag="VQO19_000781"
     CDS             complement(37958..38527)
                     /locus_tag="VQO19_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HET1349074.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(38546..39274)
                     /locus_tag="VQO19_000782"
     CDS             complement(38546..39274)
                     /locus_tag="VQO19_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HET1349075.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILWDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(39274..40014)
                     /gene="xerD"
                     /locus_tag="VQO19_000783"
     CDS             complement(39274..40014)
                     /gene="xerD"
                     /locus_tag="VQO19_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HET1349076.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQRRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(40005..40466)
                     /locus_tag="VQO19_000784"
     CDS             complement(40005..40466)
                     /locus_tag="VQO19_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET1349077.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(40463..40984)
                     /locus_tag="VQO19_000785"
     CDS             complement(40463..40984)
                     /locus_tag="VQO19_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET1349078.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(40960..41931)
                     /locus_tag="VQO19_000786"
     CDS             complement(40960..41931)
                     /locus_tag="VQO19_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HET1349079.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKIKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEKNARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(41928..42722)
                     /gene="racE"
                     /locus_tag="VQO19_000787"
     CDS             complement(41928..42722)
                     /gene="racE"
                     /locus_tag="VQO19_000787"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HET1349080.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(42929..43177)
                     /locus_tag="VQO19_000788"
     CDS             complement(42929..43177)
                     /locus_tag="VQO19_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HET1349081.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(43433..45058)
                     /gene="treC"
                     /locus_tag="VQO19_000789"
     CDS             complement(43433..45058)
                     /gene="treC"
                     /locus_tag="VQO19_000789"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HET1349082.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWTPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGIKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQTLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(45236..47203)
                     /gene="treP"
                     /locus_tag="VQO19_000790"
     CDS             complement(45236..47203)
                     /gene="treP"
                     /locus_tag="VQO19_000790"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HET1349083.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFVYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            47388..48098
                     /gene="treR"
                     /locus_tag="VQO19_000791"
     CDS             47388..48098
                     /gene="treR"
                     /locus_tag="VQO19_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HET1349084.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
BASE COUNT        14178 a        10914 c         8915 g        14149 t
ORIGIN      
        1 ctattattat ttcattttac tatactctgt taattcatat gagtttaaac cgatttcatc
       61 tttaacctcg agtaaagcag tttcaaatat ttgtttaaga gtttttgatt ctttacaatt
      121 aaccgacaaa ctttctgata aaatatgtac aacttctgag actgaataac ctatctcctc
      181 tttagaatta tataaatctg tagctccacc aataatccaa aaatactgat tttgtgaacc
      241 tacaatatcc tcattttcta cggaacttcc ttgtatcgaa caaattttat ttatctttac
      301 cataatactt caaccctttt agtgtcaaaa gtaaaccaat tcctgtcact gttaagaata
      361 gttccataat cttgttcgaa ccagtctttg gtaatttttg ttttacatct actatttctt
      421 tagatttatt aatatgattt tcagtttctc tgccatctcc aactatttta tagtttactt
      481 cttctgtctt attatcttgt ttattgtcga tcttgtcatt catttgtcta ttatctttac
      541 ttgagttaaa ctctccgttc ttctggttac tatcaattac attatttgaa ttagattgtt
      601 tttcctcttt gtttttttct ttttcgtttt tatcacttaa attatttgtt acaattttgt
      661 aaagcccatt ctccgttaca atattgaaat taccatcgct atcacgtata acaggttctt
      721 tcccatttgc attagatttg atgaatgata tatacttacc ggataaatta taaaattggt
      781 tatttaaaac ggttatttta ccctttgaat cctcaataac aattccttct ttaccaccga
      841 atatactatt ctctgagact actaaattat cactaactcg taataattca atatttggtt
      901 gttctgtttc cttagaatta ttattaatta cattttttgt tacagtaata tctgatactt
      961 ttcctaaata ttctgcacta tcttttgcaa ctcgtatcgc ttttgtttta ggatcggcaa
     1021 tattaaatat attttcggcg ataaccacct gtttatttaa atctaatagg tctttagtgt
     1081 ttttatagct ataagcattt actaaagctg ctccgttttc tcgataatgt acactctctc
     1141 ctttaacttt cttatcaaag cgatttcctt tgattaatac atcagtgaat cctgtaaaac
     1201 gtacacctgc atacatcatg ttatcaaaat gattatttaa aattttaata ttagaggggt
     1261 tctgtgttga caatgtttga tagtgtgtgc caattgctgt tactaattcc ccagatttat
     1321 cacttttgcc aaaataggaa ttttgaatag tcacattttc agattttttc ccatcatcat
     1381 tcaaggcata aggaaaacct tttctagtta atggttcaat ctgaatgctc tccttactta
     1441 tgatttgccc atccttcatc gttttgggta aggcttgccc aagaaaacga gaattatcaa
     1501 ctaatacatt tttcgaacct gcaatttgaa tagcatgccc ttgataacta tccttgaatg
     1561 ttacattttt tatagttacg ttatttgaat tcccaatagc aaatgcacct gaagaattta
     1621 taagtggtag attttttgct ttagttcctt cttcattcaa agcaccgttc atatcaatcg
     1681 taccaccaga ataactaata tcttctgttg ggccccattc tacttgcgca ccatcatccg
     1741 taaataaacc tgtcataaaa acaatggaag ggtgattctt aatatttata ccatttagaa
     1801 ttgtagcttt ctcattcaat tctaagtgtg tatgactttt taaaaaaaca atttctttta
     1861 ctaaataagt tccttcagga aaatatacat ttcctccacc tagcccttga gctgcagcat
     1921 ctattgcatc ttgaattgct tgtcgatcat catgaatccc atcacctact gcaccataat
     1981 cttttacact taaagcagta tcttcaaatt cttttttgat aattctgtca cttataacat
     2041 cttccttata actcttattt tcattagtag atgttactgt agattcaact gttctgttgt
     2101 ctaattgtga attggaacga atagtaccat tagagctgat attattaaca cttaacgaat
     2161 tatctaaacc attagtggtt gaattagagg caatcatttc agcagaacga ttctgattaa
     2221 cagttggtga attatctaaa tcattagtaa ttgcattaga agactctttt gtagccatcg
     2281 gtgaagaact agtaacaact tcatccgata aaataccttg gcttcccaaa attgaaattg
     2341 ccaatagtac cgagcaagtc cccaccttta atttacgaat actgaatacc tcattaggaa
     2401 caaaatattt catcagaacc tccaattttt ttactatttt taacaattga ttattacttt
     2461 tcttaaaata gatagaatga caccgctgtc attatcttta tcatatattt tccaaattga
     2521 attgtcaagg aataacacaa gaaaatatta aaatttatac tcttcggaaa tctcttcaaa
     2581 ctaggtcagt gccgccttgc cctaagtcta ggttactgac ttggtcagtt ctatagtaga
     2641 ctgaaactat aatagtacac ctctacttct aaaacattgt tagaaatcga tttgactgtc
     2701 ccgatcgatt tgtcctattc ttatttcctt ttactatatc tacaacctca aagcagggtt
     2761 ttgagctatc tatggccaac ttcctagttt gctctttagc cttccattca aaagtgatgc
     2821 tatctttctt agcttgaata taaaatatcc catttactat atttaaattt attgatatgt
     2881 tgtaaattat aaatgaaaga acaaatacct tgtcatacaa gcattcgcca gggatattta
     2941 catgaatatc gctcatatgg cggattgaaa ctaaaacact acaatatatt tcttaaatag
     3001 accttctata aaagctagat ttaacctcga taaaaataga tgcagtgctt ctaaaatact
     3061 ggaatagggc atataggtaa tagtagacaa gtgttttata gattgtctcg caggagatct
     3121 aatgatgtat agcaagcatc actaaacata tagaatattt gcattattat aatatcaaca
     3181 tgttataaat tctatcatgc aaaagaatga ctagaacatg aaagacaggc acaaaacttt
     3241 gaacaatatt ctgaaaacaa aaaaaagacg cgagtttcca caatctcact catggaaact
     3301 cacgtctttc aaaaaatagg gtgaattgaa aactagaaca agacactaga ttttctaaat
     3361 gatgtctagt aaggattcta aatgctacac caaattgctc acatcttatt tcaaaccacg
     3421 ggactcccac aagaaaggaa aatcctataa aaattctctc tctgaggaga aagaggcctc
     3481 aactacaggt gtaaactatt atcaattgaa aacaacagtt tttacactca attagacttt
     3541 ttagggacag gatcactttc gcttgactgt agtttgtcat ttttttgata aagttagcac
     3601 tttttcagaa actgttttga aagtctcaat gatatagtct acttcttcat cgcttaattt
     3661 agtatgaaga gggagggtaa tttcattctc aaagaaggca taggctttag gatagttcgt
     3721 catatcaaat ccaagattct tataggctgt caagagagga agcggtttgt agtgaacatt
     3781 acttgcaatt cctgctttag ccaattcttg gatgatgagg ttgcgttctt ctaggcttgc
     3841 tccttctaca cgggtgatgt agaggtggcg tgaagattcg acagtttcag tcttgtgtgc
     3901 caaaggatgg atgcgagaac ctgcaaaacc actatcatag cggtccacaa tgtccttacg
     3961 gcgttgcaac aaacttggat agcggtccaa ttgtaccaaa ccaagtgaag ccatgatatc
     4021 ggtcatgttg cacttatagg ctggtgtaac gatatcgtat tcccatgacc ccagttgcat
     4081 cttggcaaga gcatccttag tttgcccgtg aagggaaagg atttggaatt ccttgtacat
     4141 ctcttcgtca tcaatcactg gattggctct ccaagtcgca cttccacctt ctgccgttgt
     4201 aaagttctta acggcatgga atgagaagga agtaaagtca gcgatagaac cagaaggttg
     4261 tcctttataa gtagatccca aagcgtgggc actatcagag acaatgacaa tacggttaaa
     4321 ggccttttgc cacttgcttg aagcagtaaa gaagtcacgt tttttctcca cgacttggaa
     4381 caaacggtca taatcgcaaa caatccctgc gagctctact gggataatca ccttagtttt
     4441 ctcagtgata gcttgctcaa gcaggtcata gtccatctca aacgtatctg cttggatatc
     4501 caccatgaca ggggttgctc ccacgtgcgt aatgacacta catgaagccg tataggtcat
     4561 ggctggaacg atgacttcat caccaggtcc cacttccaaa acgcgtaaaa tcaactccag
     4621 agcggctgtc gcagagttga gacaaacagt cttaggtgtc tgtgtgtaaa gagacaagcg
     4681 gcgctccagt tcttttgttt taggacctgt tgtgatccaa ccagaacgca gggtatccgc
     4741 tacttcagca atttctgctt ctgtgatatc aggcggtgaa aatggaatat tgtaatttgg
     4801 cattgatttg ctccttttat ctgtactcat tttcttatga ctactttatt ttagtacctc
     4861 aaacacggtt tgaaacatga ttttgatgtc cccaaagaaa ctaaactctc ggagataggc
     4921 gaggttatag tgcatctttt caggaagaac atgctccaca taggcctgat caactgacag
     4981 acctttctcc gtcatttgac tgatgatggt gtcctcatcc ttgtagttga tgctggctgg
     5041 agaggtaatc cctgcttgca agagcaaggt tgccatcatt tcagggctat actgctctgt
     5101 ataacgtggc acttcaggtc gtgtaccgac aaaggacatc tcacctttaa ggacattgac
     5161 caactgaggc agttcgtcca aacggacacg tcggatgaaa tttccaacct tggtaatgcg
     5221 gctatcgtta gcagaagtca ccagacttcc ttttttatcc gcatccgtca ccatggtacg
     5281 aaacttccaa atcttgaacc gacggttgta ctgggtcaca cgctcttgct tgtaaatcac
     5341 tggccctttg ctatccaact tgatccaaat gctcaagatg agaaagatgg gagaagtcag
     5401 aaccagtaag accaaggcca aaacccagtc caagcaacgc ttgaaaatca gcgaaccctt
     5461 ccttttagag acaagctggt agtaagactc aacctcgctt gatttcattt ccacaggcaa
     5521 gtcttcccat ttcagcatgc tgttctcctt tgtttttatt atactatttg tcaacatttt
     5581 tcattatacc acaaaatgga aaaggcggtg aaagaaatct gtaatttgaa ggatttcctt
     5641 ctagtactca atgaaaatca aagtacagct ttgagattgc agataaagct gacatggttt
     5701 aaagagattt tcaaagagta tcggccatgg cccctgcctg caaactatac atcttgtgat
     5761 aggttcctcc cagagccaag agttcctcat gggttccact ctcgataatg cgtcccttat
     5821 ccaagacata gatgcagttg gcatcttgaa tagtagaaag gcggtgagcg atagcaatag
     5881 ttgttcggcc ctgtctcatc ttcgccagag aagcttgaac caagctttct gtttcagagt
     5941 caatattggc tgtcgcttca tccaaaatca ggattttagg ctggctggcg actgttctag
     6001 caaaggcaag aagctggcgt tgcccagtag agaagctcaa accacgctcg gaaacagggg
     6061 agtcgtaccc ctgaggaagt tcttgaataa aggaatctgc atccacaaag gctgccgcag
     6121 cctgaacctg ctcatcactg gtttcttggt acatggcgat attggactta atagttccat
     6181 gatagaggaa gggttcctgc aagaccaaac cgatgttttt tctcagctct tcttgactga
     6241 aatccctgat atccacatca tccaagagaa ctctccctga ctggaattca taaaagcgca
     6301 tgaggacatt gataatagac gatttccctg aacctgtatg acctacaaag gcaatggttt
     6361 cacccttatt aacagagaaa gaaatgtcat ccagaatcgg atgtttaccg tcatatgaga
     6421 aacacacatg ttcaaaacgg atattgcctt cttggacttt ggcttgccca ttttcttgaa
     6481 gaggttcata ggtcctctcg tctatcaggg caaagacacg acctgcagaa accatagccg
     6541 tttgcagagt tgaaaagttt tgcgtcacct caatcaaggg gtcaaaaagg cggttgatgt
     6601 actggataaa ggcatacatg gtcccgaccg ttatcccgat agaaaaacca cggtagccaa
     6661 agtaggccat caagactgca tagcctagaa gtttcagcaa actcatggca ggtctcaaaa
     6721 agagggcatc caaggctaca gaacggttgg cgtagaccaa gtgttcttgg ttgatttcat
     6781 caaattctgc ctgcaggcgc ttctcttgat taaaagcctg aataatcctg attccctcga
     6841 tattctctgc caacttacta ttgatatctg acaagagact tctggttttc tcgatgattt
     6901 tcactgactt ttttcgatag agattgacca aaaggaaaat caaagggaga aagagcaaga
     6961 ctaaagccgt caaacgaaaa tccagcacca acatggtata aagggttgtc agaaagataa
     7021 aaactgctga gataaagctg gataaaatcc cagaaaacat atcactaatc gtctcggtat
     7081 cgttggtcaa acgagaaacg atagaacctg ctggcgtctt gtcaaagtaa gacatgccca
     7141 gtttctccat attggcaaag gcatcccgac gaatatccct aacaatactg taagacacgc
     7201 gcgcaaagag aagattgcct acatactgaa ctacagtttg taggatgtag agaccatagt
     7261 agaccagcaa aacggtaacg gctagttggt taagattgct gagatactgg tcgataaagt
     7321 gggaagccac gaggggtatg acacttttaa tgaccgtcgt cgctaggaga aaactgagtg
     7381 ccaaaaaggt caggagtcta taaggcttga gataagacat caagcgcttc aatacagccc
     7441 attgttcttg tttattctgc atcttcttct cctttcattt ctaactgctg agactggtag
     7501 gtttgggcat accagccatc catcgctagc aagtcttcgt gcctgcctcg ttcgataatt
     7561 tgaccatttt gtagaactaa aataaaatct gcatggacaa cagcactgag gcgatgggca
     7621 gtgataatgg ttgtcttgtc ctttcgcgtc tccttgaggt tgtcgataat cgcatactct
     7681 gtcttggcat ctacggcgga taaggaatca tccaaaatca agatatcagg gtctaaaatc
     7741 atagcccgac tcatagccaa ccgttgcttt tgaccaccag aaagactgac tcctttttca
     7801 ccaatcagcg tatcaaatcc ttgaggcatg tctacaatat cttggtaaac tcgggctagc
     7861 ttagtagctt cctcgaccgc tgaaaggggc aagttaggat tgccaaagcg gatattgtct
     7921 aggattgaag ttgcaaagag aaactggtcc tgaggaacat agcccatgag actgcgaagg
     7981 tctgtcagac gatagtcccg aatatcgtga ccgtttagat aaatggcacc cttatccaca
     8041 tcgtattcac gcaagaggag cttgattaag gacgttttcc cagagcctgt ctgcccaacc
     8101 aagcccagtg tttgcccttt tgccaaacta aagtgaatat ccgtcagtgt ttcctcattt
     8161 tcaaaagcaa agctgtcaat ggcatactcc aaacacccat tttcaatacc atccagagga
     8221 aactcagggt cttgtacagg agattcctga gacaaaagat tttcaatccg ctggtaagaa
     8281 accttccctc gctgagtagt attaaagagg aagccgatgg ccataagagg ccagaccagc
     8341 atatccaaat agctgataaa ggtgactaga ttcccaactg taatctgccc ttcctgaacc
     8401 atcaaggagc caaccaaaag cgttaaaaca taggacgaac caacaaacac gagaaccata
     8461 gggtcaaaga gactatcata tttcatggtt tgcaggttct tttggaaggt taattcattg
     8521 actgcctgaa aagacttcaa ctcgtctgcc tgataaccga aagacttggt cactttgata
     8581 cctgatacgg actcctgtac cttgttattg agttcagaaa aagcagcttg ggattcgcca
     8641 aaggccttat gagtctttct ccctaggcga ctagtcgcat aggccatgaa aggtaggggg
     8701 agaatggcaa caagagtcat ctgccatgag atgctaaaga gcatggtcaa caaagtcacc
     8761 agagccgtga tagaggcatc caccgcagac atgacaccgc cacctgctaa acgagtcaag
     8821 gcattgatat cattggttgc gtgtgccatc agatcacccg tccgataggt ttgataaaag
     8881 gctgatgaca tttttgtgaa atgcttaaac aagcgagacc gcatgatctg tcccaagcaa
     8941 taagaggtcc caaggatata catacgccac acatagcgca aatagtacat accaaaggct
     9001 gcaagtagca agtaaaatag gctaagaagg aggtcctgct gggttaattg ccccgatgtg
     9061 atggcatcaa tgacccgccc cataaccata ggaggaatga gattgagaac ggaaaccaag
     9121 accagggcca caatcccgac tagataacgg cgtttttcta acttgaaaaa ccaccaaagt
     9181 ttttgaataa tggacataaa atccctttct gattgcaaat ggaaacctga agccaatact
     9241 caatgaaaat caaagagcaa actaggaaac tagccgcagg ctgctcaaag cactgctttg
     9301 aggttgtaga tagaactgac gaagtcagta acctacatac ggcaaggcga cgttgacgcg
     9361 gtttgaagag attttcgaag agtacaagac cccaggtttt tcttattcat aagttacgac
     9421 tgtaacagca cccttgtcat attcagcaat aaagatattg gctacattgt catgcccttg
     9481 tttactgagg ttatcaagca accactcttc gctacgacca atcgattcca agacatctac
     9541 ttgaatcaca ccgtcagtca caactggata cttagaattt tcatctccca tttgcacaac
     9601 gatgagttgc ccattttgct cttgcacagc tcgtttgact tgcttcatct ggaaaatccc
     9661 ttggccacga agtttgaggg ctacatccga tgcagacaaa ccaactgaac gacaggctta
     9721 tgggtcaata ttcccatttt tgataaggag agttggctta ccatcaatca aacgtttcac
     9781 aaagtgaaca ttgttgttga gctatttgag agtcaagacc agtttgatta aaatttcgat
     9841 ataattaagt gtcatttgtt cacatccacc agttcaattg cgtctgtctt atacaattcg
     9901 actttctcta acaggtactt gtctggctca cttccgttta gggcacgata atagcgatct
     9961 cccaccttga taagtgcgcc atctgtgttt gtggaagtat taacatagac ttctgacttg
    10021 tctactccca aatctttgga aacaacctcg atgaaatgaa gtgaagtttg aaatttattg
    10081 ttagaaactt gattgttttg ataagtcgtg atgctgacca aaagcagagc taaataaggc
    10141 cagagctgaa atcatgacca actcacgaaa ttcggttccc tttttatcat ggtatgcctt
    10201 gaaagcaaaa aaactgtcat agctaataga acaatcccaa agccaaccat gataccattt
    10261 tgctgaccga tttggctgag tacatagtca taagagtaga atttcatgta ttttcactcc
    10321 ctttcataaa atcattctta attataaacg aaagagagta atttttcaaa ccatacgttg
    10381 gggaaataga tctttttttg gtataataaa atctataatc tgaatgaaaa ggtaacttta
    10441 tgaaacttat ctcatggaat attgattccc taaacgctgc cctaactagt gactcagctc
    10501 gtgccaaatt gtcccaagaa gtcctacaaa ccttggtcgc tgaaaatgct gatatcattg
    10561 ctatccaaga aaccaagctt tctgccaaag gacctacaaa gaaacacgtg gaaattttag
    10621 aagaactctt cccaggctac gaaaacacgt ggcgctcttc ccaagagcct gcccgtaaag
    10681 gctatgctgg aaccatgttc ctttataaga aagaacttac acccactgtc actttcccag
    10741 aaatcggtgc cccttctacc atggacttgg aaggccgcat catcactcta gaatttgatg
    10801 catttttcgt gacccaagtt tacacaccaa atgctggcga tggtcttaaa cgcttggaag
    10861 aacgccaagt ctgggatgtt aaatatgctg agtatttggc tgaactagac aaagaaaaac
    10921 cagtccttgc gaccggtgac tacaacgtag cccacaatga aatcgacctt gcaaatcctg
    10981 ctagcaaccg ccgttcacct ggatttactg acgaggaacg tgctggattt accaacctat
    11041 tggcaactgg atttactgat accttccgcc atgttcatgg cgatgttcct gaacgctaca
    11101 cttggtgggc acaacgcagc aaaacttcta aaatcaacaa tacaggctgg agaatcgact
    11161 actggctcac aagtaaccgt atcgctgaca aggtcactaa atctgatatg attgactcag
    11221 gtgctcgcca agaccataca ccgattgtct tggaaattga cttgtaagga ttttctatat
    11281 ggactacaat gcggtcattc ccgagttgct tgtatcgaat atcgaacagt cccggtcctt
    11341 ctactgtgat ttactgggtt ttaggattga ataccaacgt ccagaagaaa actttctctt
    11401 tctcttgaag agtgtcaact aatgttagag gagggaacaa aggatcaact agctgaactg
    11461 acctatctat ttggtcgtgg agtcaatctc tcctttggca taaaggatgt ttcaaaactc
    11521 tatcaaagag tgatgaaggc aaactatcct atttatcgtc ccttgaccaa aagaaagttt
    11581 cgtgtcagtg atcactatat ctatcctcat gaatttgcag ttttggatcc agatagctat
    11641 tttttaagat ttagcgagta gaataataaa aattgggaaa agtctttaaa gttagaaaaa
    11701 ggcatattgt caggtgtcta aaaacttgat agtatgcctt ttatgatgga aaaatcttct
    11761 aatactcttc gaaaatctct tcaagccacg tcaacgtcgc cttaccgtag gtatatgata
    11821 ctgactctgt caattctatc cacaacctca aaacaatgtt ttgaggttgt ggatagcttc
    11881 ctagtttgct ctttgatttt catttagtat aaatgttagc ttacaatgga gtttttgttc
    11941 acccctctct tctgtttgtt cgttttttaa accaaaatac taacaaaata gttgatttct
    12001 aaagttattt agtgtaaaat aaaaacattt gctcaagcct atttaaaatt gaatatcgtt
    12061 ttacttgttt atgtcgtgaa ttggcacgac gtttctacaa ggtgccggaa cacctaacaa
    12121 taagtaagtc agcagtgaga tatggccgtt tttgccatgt ctatttgggg gacttactta
    12181 gagattaagt aggtcttttt tgaatatttt taatatttcc cttaattagt gcggacggga
    12241 ggtgaaatta tcctgtgaat aatttcagga atccagggaa tttcatccct aatttttgag
    12301 cccctagctc tttcatttct aggcttaggc taaaatagtt ccccgaacta ttttactctc
    12361 aaaaatcccg tcatagacaa taacaagatt attgtctatg ataccactac aacgggaaat
    12421 atttgataag actcgcttcg ctcgtaatag ttttatcaaa tatatagtat tagcaaaagg
    12481 gatcactata gaaacattta aacaacaagt aaattaactt ttagacttta ggaggtctta
    12541 tgaaattatt agaagaacgc atcctcaagg atgggcatat cttgggtgat aacatcctca
    12601 aggtagattc ctttttaacc caccaagttg actttagctt gatgcgagag attggtaagg
    12661 tttttgcgga aaaatttgct gctactggca ttaccaaggt cgtaaccatt gaagcatcgg
    12721 gtattgcccc agccgttttt acagctgaag ccttaaacgt tcccatgatt ttcgccaaaa
    12781 aagctaagaa catcaccatg aacgaaggca tcttaactgc tcaagtctac tcctttacca
    12841 aacaggtgac cagcaccgtt tctatcgctg gaaaattcct ctcaccagag gacaaggttt
    12901 tgattatcga cgatttcctt gctaatggcc aagctgctaa aggcttgatt caaatcatcg
    12961 aacaggccgg tgccacagtc caagctatcg gtatcgtgat tgagaaatcc ttccaagatg
    13021 gccgtgattt gcttgaaaaa gcaggctacc ctgtcctatc acttgctcgt ttggatcgtt
    13081 ttgaaaatgg tcaggtcgta tttaaggagg cagatctcta atgcaaactc aagaaaaaca
    13141 ctcgcaagca gccgttcttg gcttgcagca cttactagcc atgtactcag gatctatcct
    13201 ggttcccatc atgattgcga cagcccttgg ctattcagct gagcagttga cctacctgat
    13261 ttctacagat atcttcatgt gtggggtggc aaccttcctc caactccaac tcaacaaata
    13321 ctttgggatt ggactcccag tcgttcttgg agttgcattc cagtcggtcg ctcccttgat
    13381 tatgattggg caaagccatg gtagtggcgc tatgtttggt gcccttatcg catctgggat
    13441 ttacgtggtt cttgtttcag gcatcttctc aaaagtagcc aatctcttcc catctatcgt
    13501 aacaggatct gttattacca cgattggttt aaccttgatc cctgtcgcta ttggaaatat
    13561 gggaaataac gttccagagc caactggtca aagtctcttg cttgcagcta ttactgttct
    13621 gattatcctc ttgatcaaca tctttaccaa aggatttatc aagtctatct ctattttgat
    13681 tggtctggtt gttggaactg ccattgctgc tactatgggc ttggtggact tctctcctgt
    13741 tgcggtagct ccacttgtcc atgtcccaac tccactctac tttgggatgc caacctttga
    13801 aatctcatct attgccatga tgtgtatcat cgcaacggtg tctatggttg agtcaactgg
    13861 tgtttatcta gccttgtctg atatcacaaa agatccaatc gacagcacgc gccttcgcaa
    13921 cggttaccgc gcagaaggtt tggcggtact tctcggagga atctttaaca ccttccctta
    13981 caccggattt tcacaaaacg ttggtttggt taaattgtca ggcatcaaaa aacgcctgcc
    14041 aatctactac gcagctggtt tcctggttct ccttggactg cttcctaagt ttggtgccct
    14101 tgcccaaatc attccaagct ccgtcctcgg cggtgccatg ctggtgatgt ttggttttgt
    14161 atctattcaa gggatgcaaa tcctcgcccg agttgacttt gctaacaatg aacacaactt
    14221 ccttatcgca gctgtttcaa tcgctgcagg tgtcggtctc aacaacagta atctctttgt
    14281 cagcatgccg acagccttcc aaatgttctt ctcaaacgga atcgtcgtag ccagcctact
    14341 cgctattgtc ctcaatgccg tattaaatca taaaaagaaa taagaaaaag aggtgcgagc
    14401 ctcttttttg tttatcacaa attgattata aatacaatca atcccaattc ccatctaatt
    14461 gaattggacc tatttcaaat tctttaaaat attatgttcc aaatcgttaa tattatataa
    14521 gaatggtaaa atatcaaatg tttctcgtaa attattctta gccttatacc aaccttgtcc
    14581 atcagtaatc cacataaact caacattagg aatagcttta gtttcttcag caatcatttt
    14641 gtaagatcta gccgtctcat ttaattttga accacttcct gaataaaaat taacctcaat
    14701 cagataaagc acttgttcat tttttatgac aaaatcaaaa cgtttcacag tattcccatc
    14761 attcgtaata gcagataaat cgacagaaaa aatttcctct atttcatttt gttcaatctc
    14821 tttaaataaa ttctctccta aaatataccc ttcagcttca agatagcttt gaacaatatt
    14881 ttccatcgca tctccagtcc gatttttgcg cccattagta tccataccaa cctcaacacc
    14941 tgtaacgtag tcaactaaat ttgatactaa atgattttgc aataaatcaa atatacctga
    15001 tttttccaaa aacatagtat attcttcaat actatagttt cgtttactaa aatcaaaata
    15061 gaaatctttt atcggatcct taacaataat cgtatctctc aaacgtttag caataagtag
    15121 aggcacaact ttcaaaattt ctggataatt ttgatataag tctaaaaaat cctcttgtat
    15181 atttttacta ccaataagac tattcataat atttagagca acttttatac tagatacatt
    15241 tttataaacc ttaggaaaat ctgtataata agtccagtca gctactgtgt cggtcatcgt
    15301 tgacaaccac tcatcaaaat ttctagtttg tttcattttc tgcctccaac ctcttccttg
    15361 caatttttaa atattctttt tcagcatcga tacctataaa tcttctacct aaccgcttcg
    15421 caacaacacc cgtagtgcca ctaccaacaa atgggtctag aatatagtca ccctctttag
    15481 tagaggctaa aataatacgt tctaacaaat actctggttt ttgagttgga tgtttcccag
    15541 cccatttttc aactttcttt gttaaagaac cggtccagac atctttcatt tgttttccat
    15601 cattcaattc tttcattaaa tcataattgt agtaatgacg agctttttta tcattttttc
    15661 tggcccataa aatggtttca gtagaatggg taaaataacg acaagataaa ttgggggcag
    15721 ggtttgtttt ctgccaagta atattattca gaattttaaa accttcttgt tctaatgcca
    15781 ttccaactga gtatatgttg tgcaaactac ctgaaatcca taccgtccca ttaggcttca
    15841 gaacttcttt tgctaggcga atccatttac gattaaactc atgtttttct tcgaatgaag
    15901 aaattttatc ccaatctcct ttatcaacag aaactacttg tcccccagaa ttagatattc
    15961 caccattact taaaaaataa ggtggatcag caaaaatcat atccatactt tctggtttca
    16021 tttttgataa gaacttgaac gtatctgaat gaacaagaat catcttattt ttattgtagt
    16081 atggttttgt cataagaaca cctccatact tatattcgtt atttttcata atttgtgact
    16141 ataatttcag aaatttttcc tcgacttgaa gattttgctc cattagttcg ggtagcttca
    16201 acataatgta tattaaaatc cttatacaac tcctctacta aagcactaga agaatttgat
    16261 aacataacat aagctcctgt atcactcaat ctcttaaagg catctcttaa tcttacttga
    16321 tctgcaaaag agaatccctc atgagtataa gacgtaaatg cactcgtctc agacaatgga
    16381 atatatggag ggtcaaaata cacaaaatct cctgttcgaa catctacaat tgccttttca
    16441 aaatctccca ctttaatttc tagttgattg ttatttatat aaactgaaat agcagatatc
    16501 aattcctcat caacaatttt aggattctta taacgtccat atggaacatt aaattgattc
    16561 ttagaattca cacgatatag accattaaag ttcactctca acatatatag aatacgtgca
    16621 gctctttgta cttcggacat catatctatt ctttcatcac gatctgcaga acgtaaatct
    16681 aaataatatt cttttgaatt atattcctga tgaactttca aaatttcaat caattcttga
    16741 ggattgtcct taatttgttg atagcaattt attagttcag cgttaaaatc attaataact
    16801 gcatctttag gagccaaatc aaaaaataaa gctccacctc caacaaaagg ttcgaaatac
    16861 ctgttatagg ttttaggtat taattctcta ataacaggca ataattgtct tttaccacct
    16921 gtccatttcg tgaacggttg taaagtaact ttctttattt cttttatctt catgctttta
    16981 attataccat agaaattaaa acacaactct tgtattttct accacattac taaattttct
    17041 attttagaat taaatcatat caatatcaaa aaatgagtaa ggcaaatctt ataaattcca
    17101 aaattcacct cactctatta aattactctt tatatcctta cctgtctgtc ttctgaccgc
    17161 cggcctgtga caaacatggt aaaggttgct ttgcagacat ttctgccttc ttgattggtg
    17221 atatccacat ccattacaca ggttgtacga ccttgatgga cacattctcc tttaatggtc
    17281 aatacatcgt cgagttttcc tgccttaagg tagttgatag aggattggag tgtcacccca
    17341 tcaagtccca gcgagataac caccaaacca ctgatttggt cacatagcgt gaatagatag
    17401 ccaccatggg cattgccata gtagttgagc gacgagttca ctactttggt cgtcaccaca
    17461 acgtgaccat ctctcatttt ttcaatttcg taattttcaa aggcagatat agcgtcaaaa
    17521 tgaaagtctt tcatcgtttc ctcctgatat ttcaaacgac actatgatac tactttttat
    17581 aggactgtgc aaggagaaag ctcctagtct agtgaaattc cgacctgttc cacaaagcgc
    17641 ataaaggccg cctgtccctg ctctgtctgc ttgtagactc ctgcatcctc aagtacacgc
    17701 acaaagatag cccccacaga gtccttgacg attgcaaggg ctttttcttt atccgttagg
    17761 tctggatgtt gggatttgag ttggtctgcc cactcctgat gataatcggc aactgtaaca
    17821 gcttctccta caagatagct agcgacttgc tccacttctt ctttcagacg tggtggcaag
    17881 attgccaagc ccatgacctc aatcaagccg atattttcct tcttgatatg ttggacatcc
    17941 ttgtggggat gatagatgcc atcaggatgc tctgctgaag tctgattgtc tcgcaagacc
    18001 aagtccaact caaactgtcc atcacgctta cgcgctattg gtgtgatggt gtgatgcggt
    18061 gtcccgtctg tctctgctaa aatctgcaca ctagaatctg aatactgacg ccattcctgg
    18121 aaaatcttat cagctaagtt aatcaaatcc tctttggaat ccgaagtcaa gcgtaggaca
    18181 gacattggcc acttgataat tccagccttg acctgctcaa aaccagcaaa tcggaaggtc
    18241 ttttgcaagg gagccaattc cataggaaat acgtgacggc ctccctgata atgatcatga
    18301 gttagaatag agccccccac aatcggcagg tcggcattag atccagcaaa atatcctgga
    18361 aactgctcta cgatagccaa cagacgttca aaactctgac gactaatggc catgggacga
    18421 tgctggccat ctaaaaagat acaatgctca ttaaagtaag catagggcga atactggaaa
    18481 ccccattcct gaccaaccat ttcaaaacgg ataatccggt ggttggtgcg agctgggtgg
    18541 ttgacccgac catggtaacc ctcattctct aaacaaagtt gacactgagg ataattacta
    18601 gcttgcacca acttggctgc cgcaatctct ttcggatcct tttcaggctt agagagattg
    18661 atggtaattt caagttctcc ataatcagat ggaacacgat aagcgatatt tttagcaatg
    18721 gccttgagtt tgatgtagtc atttttctga ctgagttgat aaaaatcctc tatcgcttgc
    18781 tcaggagagt aggcataggc ttcccagaag tcacgattga cctgactcgg acaaggagtc
    18841 accaagtcca tcaattcagt accaaggatt tcacgcgcag tctgactatc ctcaatcgtc
    18901 tctaatcgaa cggcttcctc aactagctgg tccttgaggt caatcaattt atccagattg
    18961 gtctcaactt ccaaaacacc ttctcccact cgtgccaaaa cacgattggt caggtagatt
    19021 cgatccattt cctcaaatga actttcagaa atgacatgtg ttacaaattt atctactaag
    19081 atcactatag agcctccttt tgactagtca aggacgcgag tgccacctgc aacttcagcg
    19141 atatagaagc ttggagcgta tccaactact tcctcgtagt gtttgcctac agcttcctta
    19201 aaggcctcaa cagtatcttt ttgaaccaag gcaatggcac agccaccaaa accagcccct
    19261 gtcatacgag caccgagaac tccttcttgt gcccaagctg tgtgaacaag agtatccaat
    19321 tccaaaccag ttacttcata atcatgctcc agagaaacgt gtgacgcatt catcaaacga
    19381 ccaaatgttt ccaaatcacc tgcttgaagg gctgcttgag ctttaagggt acgttggttt
    19441 tcaagcacag catggcgagc acgtttcaaa cgattttcat ctttaatcaa atagctatat
    19501 tggtcaacgg cccactcgtc caattcaccc agggtctgaa tatccaaggc aacttgcaat
    19561 tcttccactg ctttttcaca ctcagcacga cgttcattgt atttagagtc cgccaattca
    19621 cggcgtttgt tggtgttcat gataacaacg acattgtcct tcaaatcaag tggcaccaaa
    19681 tcatactcta aggtgttggt atcaaggtaa atagcacgtt gatcggcccc cataccaata
    19741 gcaaactggt ccatgatacc agagttgact ccgataaagt tgttttctgt ttgttttccg
    19801 attttaacca aatcgagacg ctctaatttt aaatcaaaga gatgctctgc cacgactcct
    19861 gtcaagagct ccaaggatgc tgaagaagac aagccagcac catttgggat attcccataa
    19921 acataaaaat caaaaccttt gtcaatcacg tgcccagctt cttgcaagaa atgaaggaca
    19981 ccttttggat aattggtcca gttgtgctct ttttcaaact tgaggtcagc gagaggcact
    20041 tcgataatgc ccttgtcctc aaagttagct gagtagaaac gcaagacttg gtcgtcacgc
    20101 ttacgagctg caccgtaagt tcccaaggaa atagcagcag gaaaaacgtg cccaccgttg
    20161 tagtctgtgt gttcaccaat caaattaata cggcctggtg aaaagaaggt ttggtctgct
    20221 tcttgaccaa aaacagcaag aaagtctttg cgaaggactt cagtagtaag atgttgtgcc
    20281 atatgaattc tcctttgact gtccgttaag ccatcttaac gtgtaatcgt tttctttcta
    20341 ttgtatccaa gaaatttccc aaggtcaatc ctttttacta aaattttact aaaatatcag
    20401 taaaaagaag aaaaatatga tatactaacc taatcaagga ggatttatgg ctaccttaaa
    20461 agacattgca cagctagcct ctgtctcaat cgcgaccgta tcccgtgtcc tcaaccgcga
    20521 ccagagccta tctgttacag aagaaaccag acaccgtatt ttaaccgttg ctgaagagtt
    20581 aggctacacc aaacacctca agacaggcga gtcccacaag cccaagcaaa agattgccat
    20641 tatccaatgg gtcagcgaac aaggggagct agacgacctc tactactacc agattcgcct
    20701 aggaatagaa aaaagagccc aagagttgga ctacgatatc ttgcgctatt ttaatgacca
    20761 tccttttacc ttaagcgagg aagtgattgg gattctctgc atcggaaaat ttagccgagc
    20821 tcagatttct gcctttgaag aataccaaaa gcctcttgta tttctagaca gcgatacact
    20881 ttccctggga catacctgta ttatcacgga tttttacact gctatgaaac aggttgtcga
    20941 ttatttcctc agtcaaggga tggaccgcat cgggattcta acagggcttg aggaaacaac
    21001 agaccaagaa gaaatcattc aggacaagcg tctagaaaac ttcaaaaact acagtcaagc
    21061 gaggggaatc tatcatgatg aactggtctt tcaaggaaga tttactgccc agtctggcta
    21121 tgacttaatg aaggaggcca ttcagagctt gggagaccaa cttccgccag catttttcgc
    21181 agccagcgat agtttagcta tcggtgccct ccgtgccctc caagaagctg gaatcagcct
    21241 gccagatcgc gtcagcctca tttcattcaa cgacaccagt ctgaccaagc aggtttatcc
    21301 tcccctctcc agcatcacag tctatactga agaaatgggg cgagcaggta tggatattct
    21361 taacaaggaa gtcctccacg gtcggaaaat ccctagcctg accatgctgg gaaccagact
    21421 gacattaaga gaaagtaccc taaatcaaga ataggataac ataaaaaacg aatagagttc
    21481 taaaactcct attcgttttt tattcgatta caatcataga cttaatggtc ttacgttcat
    21541 ccatatcttt ataggcctgg tcgatatctt ccagtttata acttgaagta aagacgcgac
    21601 ctggattgat atcaccatca aggacggctt ttagtaaaaa ttgcttatcg tatgttgtag
    21661 cagaagctgc cccacctgct acagagatat tttgcataaa tgtcgaacca agagcacgat
    21721 tattatagtg tgggactcct acaaagccca tacgccctcc attatgaaga acacctagcg
    21781 cctgttctat agcagcctcc gtaccaacac attcaagtgc tgcgtctgct cctccaccga
    21841 ggatttcacg caccttggta attccttctt gaccacgttc tgcaacaaca gctgtcgcac
    21901 ctgactccat agccatcttt tgacggtctt catgacggct cataaggata atttgtgatg
    21961 ctccacgcat cttagccgcg atgacagcac attgaccaac agccccatca ccgataacaa
    22021 caaccttgtc ccctttttga acatttgcaa cacgcgccgc atgatagcct gtcggcatga
    22081 catctgcaag agtcaaaagg gactggagca tcccttctgt atagtcagaa ggttgaccag
    22141 ggattttaac cagcgcccag tttgcatagt ggaagcgaat atattctgcc tgaaaatcac
    22201 cccccaaatt attgccaata tgattgtcgc aagaaccgtc aaatccagca agacaggcat
    22261 cacactcacc acatccatgt gtaaaaggga caatcacaaa atcacctggt ttcaccgtcg
    22321 taacggcttc cccagcttct tcaacaatcc caatcgcttc gtgtccacta tttttgtgtc
    22381 cagctttcgt ttctggatta cggtacctcc ataaatctga accacaaacg cacgcacgaa
    22441 ccacacgaat aatcacatca tccgcttcta ttatttgcgg acgttcaatg ctagcaagtc
    22501 caacctgacc tgcctttgta tatactgctg atttcattta aaattttcct tccttataaa
    22561 gtttaatttt gagatttaaa cgatttaaag ctgtctgtag ctgagacaag cgctcctcta
    22621 atttttgctt ttcctcttct aaaataccaa gcctctcctc tctcgtttca tctccctttt
    22681 ggtagagcga catatagtca actaaactat ctacagagac acccgccgaa cgaaaacact
    22741 taataaattc cagcgcttcg atatcctgat cttgaaaatc acgaatccca gtagcagtac
    22801 gagtaatcgg tggcacaaga ccaacccgtt cataataccg aatcgtatcc gctgaaattc
    22861 ccaacaaatc actggcagat ttaatattca cacgctaacc tcctctcatt tcattcactg
    22921 aattcacgct attctaactc acttatctta ttatataact ttgagttgac tccaagtcaa
    22981 gcattttgta tctaatcgaa aaatttttat cattaacaat catatatatg gagtttatac
    23041 aatgctcttc tcttaccaat ttttgaaata tttaaataat aaagaaatta ctctattcca
    23101 aataagatag tacccaagta tttttcactt ttttctaatg ttggtgctca taactccgtt
    23161 ccaagtcaca cacctttcgc ttatgggttt ggtgagtttc taggtcagca tcaatttcaa
    23221 tggtaatatt ttgaaaacca caatctttta ggaaaattcg aatagactct ttacaagttt
    23281 ccatatgttc catttctttt agacaaacat ggacaatggc atttttttcc aaagcatcca
    23341 tagtccagag attaagctga ttaaggctga ccacattgtc caatcgctcc aggccactct
    23401 ttacttgctt gatatcaaga ccttctggca cagcatccaa gaaaatcttg agtgtagacc
    23461 aaaaacgtgg aagggctttt gaaagaataa agaaagaaat gacaagggac aaaagaggat
    23521 ctaggatata ccagtccgta aatcgaagaa caatcgccat caggataaca gctacccacc
    23581 ctagcgtatc ttccagaaaa tgcagactca gaatagactc attctttgtc tttcccttac
    23641 caaccaccag actcgctaac agattgatag taatcgcaat aattcctaac cagagaatcc
    23701 cctcatcatt gactggttgc ggatgcaaaa tcttcgtgac attttccaaa atgactagaa
    23761 cagagcctgt tacgagaatc acagctgtta ccaaggctcc tagcaggcta aaccgcttat
    23821 agcccaaggt gtactgattg tcttcttcac gattggagat tgtttctaga aaagctgata
    23881 ttccaattgc aatcacatct cccaagtcat gcacagagtc agcaagaaca gcgctagaac
    23941 caaatactcc acctgcaata aactcaacaa tggcataagt caaatttaag aaaaaagcca
    24001 cccaaacagc atattttgcc ttcatatttc tcattccttt gttataatag gtttatgaac
    24061 accttgttca ttatcattat ccactaaaac tcaaagaaag gatagaagca aaacgtcagc
    24121 tttattcagt tctgaacaat ttgccttaag tgtccatatg actaacattg accgccgtat
    24181 cagcaaaacc aaaaaagcca tctatcaagc ttttatacaa cttttgaatg ctaagggcta
    24241 cgaggccact actgttcagg atatcattaa tctcgcagat gtgggacgat ccacctttta
    24301 ctgtcactat gagagtaagg agcttcttct ggaccagctc tgccgctacc tcttccatca
    24361 tctttttgaa agagagcaag ccatttcaac cgaggactac ctcgcccacc tctttctcca
    24421 ttttcataaa aaccaagacc atatcaccag tctgctattt tccaaaaatg actacttcct
    24481 ccgtcaactc cataaagagc tagaacacca tgtctattcc gtgctagctg ataatttaaa
    24541 agaagcccac cctaatatgc ctacttctta cctccaacac ttggtcgtgt ccaactttat
    24601 cgagacattg acctggtggc tcaaaaaagg tcaagatttc acagaccagg aagttgtcca
    24661 attttatcta gaccttctca ttcctaaaaa ttgaatatag agtaaagctt cagttgtctt
    24721 atttctaggt tactgagttt tttatctttt caacaacaaa agaggacccg ccgatcctct
    24781 ttttcatact ataaatcctt gattatcaac tatatctgtt ttaatcaaaa tctcaaaaca
    24841 gcactttcaa acatcttttc ctagttaagt aaatcagtat tctgcttagc tgccttgctc
    24901 cattgatacc aaccaactag actgttaatg agataaatta gatatttccc ttgaatttgc
    24961 aggctttctc cccaccagag atagattgaa aaaacattgg tagccgccca gaatatccac
    25021 tgttcacggt aaacagctgt catgaggatt tgccctaccc cattggttgc atctgtgatt
    25081 gaatcacgat agggacgatt ggcaccaata gactgataaa tgaagccaaa ggccaaccac
    25141 caaagcacac taatggaaag atactttgtc cagcccttgc cgtccagttt acgcgcgaca
    25201 aactcctgct tttccttctt aaactgtgcc tgataaatcc aaactagaag tccaattggc
    25261 tgcatgactg tgaagtaaag tgtcgtcagc acctcaccat aaaagccttt ctgtagggcc
    25321 aaaataaggt aaataacaga gttaatcaag ccaaaaagat aattacttgc tcgaccttcc
    25381 gatacaaaga ttacacagat aatccctgtc aagctacaaa tcatcccaat ccagtcaaca
    25441 atacgatgtt cgtaaaccaa ctccagccag agaggaaaac ttcctaaaac cagcaaataa
    25501 atccactggg caaaactacg atgggcaaag aggtcatccc agatagcctt catagttcct
    25561 gaaaatccta aatcagccat agccgcaacc atacgacggt aaccacctga catttcacct
    25621 agggttgttt tgatattttc aattttcttt tgcaaataag tatgcatcat ttctcctttt
    25681 gtttttaaag agccgtgtct ggatagactt tcggacgcaa cgctctatta gataatgaac
    25741 tgcctataca caagatttct aaccttagtc gacatgagct gaaacctctt atttgttaag
    25801 tagttcacaa aatattatac acctatttta tgaatagtca actgtcttta cagtaaaatt
    25861 ttagaaaatc atgaaaattt tctctttctt tccattttaa gtgacattca gtcattctca
    25921 catcaaaaaa gcccagacga aattgtctga gcattctttt atctagtcgt ttaaggaagt
    25981 tgagttcagt atgtttaaag tctctgtccc atcatttctt caacaaacct tgttcttgga
    26041 gaaactcctt ggctacttgc tttgctgact tgccttcaac accgacttgg tagttgagct
    26101 ggctcatctg gctttctgta atcttaccag ccaatgtatt aagaactctt tccaactctg
    26161 ggtgtttctt gagaagagct tctttcatga gtggagcccc ttgataaggt gggaagagtt
    26221 gcttgtcatc ttccaagacc tgtaaatcat aacgctccaa ttccgcatca gtcgaatagg
    26281 catccgtgat ttgaatatcc cctgactgaa ttgcctgata gcgaagagct ggctgcatag
    26341 tcgccacatt gagattgaga ccatacattg attgcaagcc cttatttcca tcttcacggt
    26401 cgttaaactc aagcgtaaag cctgccttca gctgcccttc cacttttttc aaatccgaaa
    26461 tggtcttcaa gccatattct tgagcaatct ttttcggaac agctacagca taggtatttt
    26521 gataagacat aggtttgaga taggctagat gatcctgctt ggcaattcca tcacgcgcca
    26581 cttgataaac ctgctctggc tcatgactca ccttgggtga tggttgaagc aaactttcag
    26641 tcaccgtacc ggtaaattca ggataaatgt caatatcacc ttttttcaga gcttcataaa
    26701 ggaaacttgt cgtcccaaaa ttcggtttaa cagtcgcagt catgctggta ttttcttcaa
    26761 tcagcaattt atacatatta gccaaaattt ctggttctgg gcctattttc ccagcaataa
    26821 tcaagttttc cttctctttt tgagccaaaa gggctggact ataagacaga cccagtaata
    26881 aagccatcaa ggcaaaacca gagaaaatcg tccgcaattt cgctttttcc attactttta
    26941 gtaggaagtt aaaggcaata gctagcactg cagaagaaag ggccccaatc aaaatcaaac
    27001 tggcattatt acggtcaatt cccaacagga taaaggaacc cagtccccct gccccaatca
    27061 aggtcgccaa ggtagccgta ccgataatca agaccgctgc cgtccgaatt ccagacatga
    27121 taacaggcat ggcaagtgga atttcaaact tcttgagacg ctcccatctg gtcatcccaa
    27181 aggcaatccc agcctcttga agactcggat caattccctt cagcccagta atagtatttt
    27241 gtaaaatcgg aaaaatcgca taaatcacta gagctgtcaa agccggcaag gtcccaattc
    27301 ccatcaaagg gataaagagc cccaacaagg ccagagacgg gatggtctgg aaaatacctg
    27361 caatctgcaa gacccagtcg gccagcttct catgatagcg aagaaaaaca gccaagggaa
    27421 tcgcaagcaa aatagctagt aacaaggtca aaagtgacaa ctgcaaatgt tgagatagag
    27481 ctgtcaacca atcactaaaa cgatcctgaa aagttgcaat taaattagtc atgaacacta
    27541 cctccaaaca agtctgctac aaagtctgtt gcaggcactt ttaaaattgt ctcgggattc
    27601 gctacctggc gaatttctcc atcctgcaag acagcaatac ggtccgccaa cttcaaggct
    27661 tcatccgtat catgggttac aaaaatcgtt gtcatcccaa actctttatg caattctttt
    27721 gtcagaacct gcaactgttt tctcgaaata gcatccaagg ccgaaaaggg ttcatccatg
    27781 aggaaaatct tgggctgacc aatcatagct cggacaatac cgacccgttg ctgttctcca
    27841 ccagataatt cactaggtaa gcgatgccca tactcggcta ctggtaaacc aaccttagcc
    27901 aaaagctctt ctgttttctt cgtaatttct tccttgctcc accccttcat ttcaggaatg
    27961 agagcaatat tttccgcaac tgttagattt ggaaaaagag caatagcctg taaaacataa
    28021 ccagtagaaa gacgaagttc acgctcatca tagtctttga tgcgcttccc atccatataa
    28081 atatttccat cagttggttc caaaagacgg ttaatcatct tgagcatggt cgtcttacct
    28141 gacccagaag gccctactaa aaccataaat tccccatcct caatctgtaa gttgacatct
    28201 ctcaagacat ccttttctgt gtagcgcagt gctacatttt tgtattcaat cattctttgt
    28261 cctcaattta aaacttccct cgattagtca agtcttctac cttaggcatg acttccttat
    28321 tatcccaatg ctccacaatt ttcccgttct ctaaacggaa gatatcgtac tgggcataag
    28381 caacgccatc aatctgagtc tgaccatagc taaccacata gtttccttgt cctaagagtt
    28441 ggaaaacaaa gtcaaaagtg acactatatt cagccacata gtttttataa gcagcacttc
    28501 cttgtccaat ctcatgatta tgctgaatca aatcgtctgc cacataatca ctccactgct
    28561 ctagctcccc attttggaaa atttctgtca agaaacggcg aaccagcttt ttattttctg
    28621 ctttcttatc caaatccttg atttcaaaat ctccaaaaat ttgatctagt tgatcatttt
    28681 caggtgttcg atagtagtca atgacatccc aatgctcaac aatacgacca ttctcatccg
    28741 cacggaaagt atccgtcgtc acccattgag cttctccacc attcagatat tgatgaacat
    28801 gaacaaagac cagattgcca tcctcaatgg tgcggacaat cttaatctga cgctctggat
    28861 gacgctcaaa gaaatctgca aagaaggctg caaatccttc tttcccgtca ggaacacctg
    28921 tcgaatgttg gatataggta tcccctacag actgggcttg agcctcagca actcgtccgt
    28981 cttgaatggc atggatgtat aggttgtgag catttttcac ttgttgtgac atattctaaa
    29041 cctcatttcc cttctctttc aaattcgcca aaattctttc ttgaaaacct tcaaattggt
    29101 gaatttcttc ctctgaaaat cctttgtaaa agatagtatc caatttctga ctgacacgat
    29161 gccccacttc tttctgggac ttgcctaact ccgttaaaac taaatacttc ttacgcttgt
    29221 cttttccaca cggactaaca attacaagct tttgttcctc tagctttttt atcatagtcg
    29281 tcagcgtatt attcgcaagc ccagtcgcaa gcgcgatatc tgtcgcagtt gcgcagccag
    29341 tttcactatt ccataaaacc gctaaaatct tgccctgttc acccctataa agagcctcag
    29401 gatcttgact cagtaacttt tgaaaaatcc gcccattcaa caaacgaata tgatgggcta
    29461 gcaaatgact atctttcata acacctccaa tttatttcga tgtcgaaatg aataaaataa
    29521 ttgtaacact catcgttcta actgtcaact atttcgattt ggaaataatt tttgataatt
    29581 attcacacca ccatactccg gctcaactaa cttttaacga gagtttctaa attccttcgt
    29641 cctccagtct acaaaagcct tccatccgta ctatcctatt ttttatgagg ggacacattt
    29701 ttcctatcag atcatttatt ttaaagatag aagtaaatca taattgcttc catctgttct
    29761 tttatagtat attgaagttg gactagggca ctgtatcttc taaaacattg atagaaagcg
    29821 atttgaattt cccaatcaat ttgttcgtct ttatagcatt tcgaaactgg aataggacac
    29881 catgactgct aaaagatttc tataaattca tttgatttcc ctaatcaatt tgttcatatc
    29941 ttatttcatt ccgctataat ttcaccttac cctatctttt tcgtagcacc cttcaaacag
    30001 cctatcccct accgtttgac gattcctcac ttcactccac ttccattaca gaagtttctt
    30061 cactactatg gtctcggctg acttctcatg attccttgtt actactattt gaacgctcac
    30121 gagataggtc ttataaaaaa tgctttgatc cacaatggaa tcaaagcatt ttaaaaagtt
    30181 cctcatacat aagtgcagaa gtcgcagttc ctctgtactt ggcttcttct cttttgataa
    30241 agcgagccaa gttgagcaac tcaggtgctg gatgtttggg atttaggagc aattcacgat
    30301 tgaccaggcc tgagagacga actgcctgca attgctcatt tgtagtaggc agttttttag
    30361 tagtctctag gagagcagca actaaatctt cactcaaatc atgtcgagca tgattgtaaa
    30421 gatcttttat aaggctttct aggtttggtt ctgccatccc taccacctcc cttatggttt
    30481 aataatgttt aatcaaatca accgttgaac gatccaattt cttcaccaag gcttgtaaga
    30541 aagcttgcgc ttctaggaag tcatccattg catagagggt ttggtgagaa tggatataac
    30601 gagcgcagac accgatagtt gttgatggga caccaccatt tttcagatga gctgcacctg
    30661 catctgttcc gcctttacca cagtagtatt ggtacttgat accagcttct tcagccgttg
    30721 tcaaaaggaa atccttcatc cctgggagaa gcaagtgacc tggatcatag aaacgaatca
    30781 aggttccatc tccaatcttg ccttgaccac cgtagacatc acctgctggg gagcaatcaa
    30841 ctgctaggaa gacttctggg tcaaacttgg ttgtagaggt atgagcgcca cgcagaccaa
    30901 cttcttcttg gacgttagaa cccagataga gttcattgcc gagtttttga cctgataaag
    30961 cttcagctag ctcgcttacc atgaggacac cgtagcggtt atcccaagct tttgagatga
    31021 tatttttttc attggctgtc aaaattgcag aactatctgg tacgatggta tcaccaggac
    31081 ggatgccaaa actttctgcc tcagccttgt ccgcaaaacc accatcaaaa acgatatcgg
    31141 caatggctgg catggttggt cccccctttc cacgagtcaa atgcggagga acagaacctg
    31201 aaatcacagg aatttcatga ccatcacgag tcaagagttt gaaacgttgg ctgctaacca
    31261 ccatggggtt ccagccaccg atttctacga cacggaaggt accatctggc ttgatttcgc
    31321 tgaccataaa accaacttcg tccatatgag aagcgaccaa gacgcgcggt gcatccacag
    31381 cttctgaatg tttgatacca aaaataccac ccaagccatc tgtcaccact tcatccacat
    31441 gcggtgtcaa cttttcacga agataagcac ggacaggcgc ttcatgacct gagactgcag
    31501 caagttctgt tacttcttta atttttgaaa ataatgttgt catttcagtt ccttctttct
    31561 ttcatccatt ttaccacttt ttataggaga aggatagtgg gaaggtggat ttctaagtta
    31621 gtatcttagt cctgctctat cttagaaaag gatagtattc tcttgcatgt agtgcaaaat
    31681 ctagtaaaca ttccaaaatt aactcgaata tttatttcca aacaaaaaac aatacaccat
    31741 caaagttgtt tggatttttc atgaaattta cagaaaatag ttgacttccc tttcttcttt
    31801 ctttaaatat atagttggtt gagtttggaa tagtacgctg tagctgctaa aacatttcta
    31861 gaaattaatt tgactttcct aatagagttg ttcatatctt atttcaattt actatagtac
    31921 aaaactagaa aaggaaaaaa tcatgaccaa aacaattctt gttacaggtg ggactagcta
    31981 cattggctcc cataccgtta aagctctttt aaatgctggc tataaggtgc atgtcctcga
    32041 taatctctcc acaggaaatc gagcggctgt ggatagtcgt gctagcttta aagaactgga
    32101 tgtttatgat gctagcgcct taaaggctta cttaaaagaa aatcagattg atgctgtcct
    32161 ccattatgca ggtgaaattg ttgtgagcga aagtattgaa aatccaagta aatacttcac
    32221 tgccaacgtt gctggtagga accaagttct caaagtctta tctgaagttg gcactcaaaa
    32281 aatcatgttc tcttcgactg cttctctcta tggaaataac tgtattgaca agccggcgac
    32341 tgaagatacc ctgatcgacc ctgtcaaccc ttatacagag acaaaactga tgggcgaacg
    32401 aatgatttac tggatggcca atcgctacga ctggaaatat gttattttcc gttactttaa
    32461 tgttgctggg gctgaaatgg atgcttcaaa cggtctgcgt gtgaaaaatc caactcacat
    32521 cattccaaat atcaacaaga ccgcattggg acaaaatgat agcttaaaaa tatttggaga
    32581 tgactacgat acacgtgacg gttcatgtat tcgagattac atttatgtct tggaccttgc
    32641 ataggctcat gttaaaggaa tgaactacct atttcaagaa gacagttctt ctcaaatctt
    32701 taacttagga actaaaaaag gctatactat caaagaaatc tttaaaactg ctgaagaatt
    32761 actaaattaa aaaatcccac acgagattgt tgctcgacgt gctagtgacc cagccagtgt
    32821 cctagcagat gcttcaaaag ctaaacaata tcttgattgg acggctagct actccctcga
    32881 agatattatt ttatcagatt aaggtaaaaa cattttagaa taggataaca aaggagaaag
    32941 tcttgttgct ctctccttgt tgtatttatt aaattgtcag aaattttatt gacagattag
    33001 aaaaataatg ttacatttat atccgcagat atctttcgat accaaatcta catgaaagga
    33061 cggggtatga aactttctca ttatttaatt ggcttacttc tactcctagt ctttctctct
    33121 attagcattg ggaccagtga tttttcatgg ggaaagctat ttgatttcga ccagcagacc
    33181 tggctcctct ttcaagagtc ccgtctccca agaactatca gtattctcct gactgcctct
    33241 agtatgagta tggcaggcct tctcatgcag actattaccc aaaatcagtt tgctgcaccg
    33301 agtacagttg gaacgactga agccgccaaa ctgggaatgg tgctgagcct ttttgtcttt
    33361 ccatcggcta gtctgaccca aaagatgctc ttcgcttttg tttcatccat cgtattcacc
    33421 ctcttcttcc tagcctttat gaccattttt actgtaaagg aaaggtggat gttgcctctg
    33481 attgggatca tctatagcgg gattatcggc tcagtcacag aagttatcgc ctatcgtttc
    33541 aatctggttc agagtatgac tgcctggacc cagggctcct tctccatgat tcagacccat
    33601 cagtatgagt ggctcttctt aggcctcatc atcctgataa ccgtttggaa attatcccaa
    33661 accttcacca tcatgaatct agggaaagaa accagcgaga gtttggggat ttcctactcc
    33721 ctacttgaaa aactggccct ctttctggtg gcgctaacga caagcgtcac catgattacc
    33781 gtgggtggcc taccatttct cggagttatc gttcccaatc ttgttcgcaa gtgctatgga
    33841 gataatctaa gtcaaaccaa actcatggtc gcactggttg gtgccaatct agttctggct
    33901 tgcgatatcc tatcccgagt tctgattagg ccctatgagt tgtctgtcag tctcttgcta
    33961 ggaatcatcg gtagtctcgt ctttatccta cttctctgga gagggggacg aaaagatgca
    34021 gactaaaagc aaacatacca agctcttctg gattctcatt attcttgcca tcggagcttg
    34081 tcttctctac ttttggccca tcactcactt gtcagccttt gcttggaagt tgcgttccca
    34141 aaagatcatc gtttatctct tggtagccat cgcgactggg atttcgacca ttagttttca
    34201 aaccttgacg gaaaatcgct tcctgacgcc tagtattttg ggaattgaat ccttctacgt
    34261 cctactacaa accctactac tggtttttga aagcaagttt cttcaacttg gcaaatcccc
    34321 tatcttagaa ttcctagtct tacttcttgt ccagtccctc ttctttctcg ccttacaagg
    34381 ttacttgaag acactgatga agcaagacct ggtcttcatc ctgctgatct gtctagcgct
    34441 cagaagtctc tttcgaaata tcagcacctt ccttcaagtc ctaatggatc caaacgaata
    34501 cgataaactg caaaatagtc tttttgcctc ctttcaacat cttaacactt ccatcctagc
    34561 catcggttct ctgatcatcc tcgctttgac aatctttttc tttcgaaaag cagtcgttct
    34621 agatgtcttg cacctgcaaa gagaaacggc tcagatattg ggactcgatg ttgaaaaaga
    34681 acagaaagag ctcctctggg gaatcgtgct tttgacctca acggccactg ccttggtagg
    34741 acctatggcc ttcttcggct ttatgctggc caacctcacc tacctgattg tcaaagacta
    34801 tcagcacaag ttactcttta tagtggccat tctggttgga tttattagct taaccttggg
    34861 gcaagccttg attgaacgag tctttgcact ggaaattcgt atcagtatga tcattgagag
    34921 tgtgggtggc ttcttattct ttatcttact atataggagg gctcgtcagt gaaactggaa
    34981 aacattgaca aatccattca aaaacaggat attttgcaag gcatttcgct tgaagtcagt
    35041 cctcaaaaac tgacagcctt tattggtcca aatggtgctg gaaaatcgac tctcctctcc
    35101 atcatgagca gactaaccaa gaaagatcag ggagttctca gtatcaaagg acgtgaaatc
    35161 gagagctgga attcgcaaga actggcccaa gaactaacca tcctaaaaca gaaaatcaat
    35221 taccaagcca aattgactgt tgaagaactg gtcagttttg gacgttttcc ctacagccga
    35281 ggtcgactta gatcagaaga ctgggaaaaa atccgagaaa ctctgaacta tttggaactg
    35341 accaacttaa aagaccgcta catcaatagc ctgtcagggg ggcaactcca gcgcgtcttt
    35401 atcgctatgg tactggccca ggatacggac tttatcttgc tggacgaacc actcaacaat
    35461 ctcgatatca agcaaagcgt cagcatgatg caaattcttc gacgactggt ggaggaactc
    35521 ggcaagacca ttatcatcgt cctccacgat atcaacatgg ccagtcagta tgcagatgaa
    35581 attgtcgcct tcaaggacgg tcaggtcttt agcaagggaa gcaccgatca aatcatgcag
    35641 gctgacctgc tcagccaact ttatgagatt cccatcacgc tagctgatat caatgacaaa
    35701 aagatctgta tctatagcta gtaacataaa agctcaagtt agagaacctt cagtctctta
    35761 atcaataaga tcaagagact ccctaaatcg ttatcacatt ttaaaaagga gaaattatga
    35821 aaacatccct taaactttat ttcactgccc tagtggccag cttcttgctc ctacttggtg
    35881 catgtagtac aaactcaagc actagtcaga cagagaccag tagctctgct ccaacagagg
    35941 taaccattaa aagttcactg gacgaggtca aactttccaa agttcctgaa aagattgtga
    36001 cctttgacct cggcgctgcg gatactattc gcgctttagg atttgaaaaa aatatcgtcg
    36061 gaatgcctac aaaaactgtt ccgacttatc taaaagacct agtgggaact gtcaaaaatg
    36121 ttggttctat gaaagaacct gatttagaag ctatcgccgc ccttgagcct gatttgatta
    36181 tcgcttcacc acgtacacaa aaattcgtag acaaattcaa agaaatcgcc ccaaccgttc
    36241 tcttccaagc aagcaaggac gactactgga cttctaccaa ggctaatatc gaatccttag
    36301 caagtgcctt cggcgaaact ggtacacaga aagccaagga agaattggcc aagctagaca
    36361 agagcatcca agaagtcgct actaaaaatg aaagctctga caaaaaggcc cttgcgatcc
    36421 tccttaatga aggaaaaatg gcagcctttg gtgccaaatc tcgtttctct ttcttgtacc
    36481 aaaccttgaa attcaaacca actgatacaa catttgaaga ctcacgccac ggacaagaag
    36541 tcagctttga aagtgtcaaa gaaatcaacc ctgacatcct ctttgtcatc aaccgtaccc
    36601 ttgccatcgg tggggacaac tctagcaacg acggtgtcct agaaaatgcc cttatcgctg
    36661 aaacacctgc tgctaaaaat ggtaagatta tccaactaac accagacctc tggtatctaa
    36721 gcggaggcgg acttgaatca acaaaactca tgattgaaga catacaaaaa gctttgaaat
    36781 aagccacttc aaactcaatt taatactcaa tgaaaatcaa agagcaaact aggaaactag
    36841 ccgcaggttg ctcaaaacac tgttttgagg ttgcagatga aagctgacgc ggtttgaagg
    36901 gattttcgaa gagtataaaa ttttgacatt ctaaaacgca tcctatcaag ttcactcaaa
    36961 cctgatagga tgcgttttta tcattttgaa atctatttac cccacctcat tccccttctt
    37021 gatttcgttt aagggaaaag tggtctggaa cggggtcctt acctgttttc gaccagggat
    37081 gacaacgtaa aatccgagcc aagcccatca ataccccctt aaaaccatgt ttttcaatag
    37141 cctgaatcat gtagttggaa caagtcagct caaagcgaca agagggtgga aagactggtg
    37201 agataaaacg ttggtaaaag cgcacaggcg ctattaaaat tcgtttcatt atttcttagt
    37261 tacagccatg gtgtgtagtt ggctgatttc ttttttatta agacgacggg attctcctgg
    37321 acggagtcct gtcaagtcta ggtgtccgaa acgagtccga gacaacttat ctacttggag
    37381 accaacagct tcaaacatct ttttaacctg atggttacgc ccttcatgga tggtcaactg
    37441 caccacagag cgatttttga ctgggtccac tttgagaatt tcataaacag ctggcttggt
    37501 tttcttacca tcaatctcaa gaccacgggt caaggggcgg agattgtcct tattggccac
    37561 acctttaaca cgcgcgacat aaaccttgtc aatctcatta cgagggtgaa tcatctcgtc
    37621 tgtaaagtcc ccatcattgg tcaaaatcaa gacacctgat gtatcccagt ccaaacgacc
    37681 cacagggtaa atacgttctt tgacattggg caagaggtcg acaaccgtct tgcgaccctt
    37741 atcatctgtc acactggaaa tcacaccgcg tggtttgtta agcagatagt aaaccttttc
    37801 ttcgttgtag ataggttgac cttcaacttc gaccttgtcg cctgacttga tagtggttgc
    37861 tagttcacgc accacttggc cgttaaccgt caccaagcct tgcttaatca gctcttctgc
    37921 ttttctccta ctggccacac ctgcgtgggc aatatactta ttgattctca tcttcttcta
    37981 tcctttcacc aaataattgg ctttcttggg cttgaatctc aagctcatca atcactggta
    38041 attcttctaa atggtttatc cccatgtaat ctaggaaata atccgtagtc acatagaggt
    38101 tggggcgccc caatacttcc tttttcccgt cttcctttat caggtcaaaa gcctgcaact
    38161 ttgccaaggc tccactcgag ttaaccccac ggatggcatc aatttctatc cgcgtaatcg
    38221 gctgtttgta ggcaataatg gacaaggtct caagggcagc ccgagacaag ctctggttga
    38281 taggcgcctt agagtattcc ttcaaaatct ctgcaaattg aggcttggtc accaatctat
    38341 aagcaccact tgtctcaatc aaagccaaac tggaatctgg gtccttttca tacttctggg
    38401 ctaattttcc taaactttgc tggatgcctg tcggtggcag agagaggagt tcagctaact
    38461 ggcggacccg aatcccatct tcacccgcta caaacaagag cgcttctatt tttgctaaag
    38521 tactcatctt tcctctctat caagtctagc tttgaggcac ttgactttct tccttctttt
    38581 ccatgagata gatatctcca aaactctcct cttgcacgag gatcagctcc tgggttttga
    38641 ttaactctag ggttgccaaa aagagggtga tgacctcttg gacattctgg gcttccttga
    38701 acaaatcctg caagcgcaat tgatctcgtc caatcaagga ttctttcaca ataatcatca
    38761 tgtcctcaat cttatactca tcccacaaga tagtcgtgtg attttgtgca aactcctctt
    38821 ttttcttggc taggatattt gaaaaagcca aaaagaggtc aatggtcgtc ttgtcatgca
    38881 caagctccgc atcttcgtaa atcaactctg tcggcgcttt ggaataatac tgggcccgtt
    38941 cttggtgctt ggcttccaag tgctcaccca agagcttgaa cttgcgatat tcttcgattt
    39001 gagagaggag gtcctgctcc aggtcatccc ccaagtctgt cacttctgct accttcggaa
    39061 ggagtttacg actcttaatc agcatgagct gactagccat gaccatgtac tcacccgtca
    39121 cttccagacg catggcctgc agggttgaga cataggctag atactgttcg atgacttccg
    39181 taatgggcac atcgtagata tccatctggt acttagaaac cagatgcaag agtaagtcca
    39241 ggggtccttc aaaatctttt aatttaatat ccattatcta tatttttcta aggtcaggac
    39301 tgtttttaat cctaattttt ttgcaatttc gtacaaatcg accttgtttt ctatttgtct
    39361 tagaataaac tgttcacgta agacttgagc tgataaggat ggaaaacctt tctccttgac
    39421 aaaagattct aactgacgaa aggcccactg acgagaatag ggtttccctc ctctttcaaa
    39481 aagataggtc tgccccatca agggttccaa ttctgaaagc aaggccgtgg gaatggtgac
    39541 aatcctccgt tgggaagcct tgctgattcg caacacctga aaatccagat tgatgtccgc
    39601 aaccttgatg gctaaaatct cactgggcaa gagccccatt tctaggatta agagcgctag
    39661 caagcggccc tctggatggt cgctttcctg ccaaaaagag tctaggtata gaatctctgg
    39721 cttttccgtc ttcttttcag cttgtttggc taattccaag cggtaaaagc tgtccacctc
    39781 tcctttttga tagagaaagt atagaaattg gttacaggcc gaaatctttc gcttctgggc
    39841 gctgattttt agattggcta gctgggcttg gtaaatcttg agactggtct cagaaatccg
    39901 ctcacctacc atgtctaaaa attgctccaa atcatactta taggactgct tggaattgac
    39961 agacaagccc tgcttttcct ctaaaaaggc tgaaatcctg tctctcattg gcatcgaatc
    40021 tcatattcct tactaaagtc atgcaagagg gcattaacgg ccttgaggat ggacttgcgc
    40081 gtaataatcc cttggaaaat accctctgca tccacaaccg gtaagaagga ctcatctact
    40141 agcttgtgca agacctccgt aatggtgaaa tcaggcgaaa caaccgctac gtccgttttt
    40201 gtcatatgaa cgatatccgt atccgccatg atttcttggc tcaagtcatg ctccatctga
    40261 taagccataa tatctctgag tccaatcgtc ccaacaaact gtttttcatc tgtcacaacg
    40321 ggaacacggg tataggtcat ctgactgagc aagagggtcg catgatccgc attgtgagta
    40381 tcaatcaaca cagctagatt tttagcaggg gtcaaaaaag tttcctcctg ccccaacaag
    40441 aaagtctcaa actccttggc aatcatcggc taaactcctt ggacaaacct ggatacacct
    40501 cgtgatctcg tgtcaaaaag tccactttga agtaactatc atcaatctcc acacgagcat
    40561 agagacattc tctgatggta cctcgtggtt gactgataga gcctggattt agaaagagga
    40621 tcttgccttc caaccaagca cttggcacat gcaagtgacc atagaggcag atagcggcct
    40681 cttcctcctg agcccagtag tccaactttt gaaagttgaa attgatgtca aacaagtgac
    40741 catgagtttg gataatcttg gtcgaaccaa gctcagtcac cagacgttct gggtagccgg
    40801 cgtagaagtc catgttccct ttaacaacgc ggatgccctc ccaaagtgga gaatccggac
    40861 gtagttcaga atcgccgtta tgaaaaacgg catcgacttt gcccacatag cgatcacgga
    40921 cttcttccac aatcaagcta tcgccatggg aatcgctcat tacaatgatg gtttgctttg
    40981 ccatgatgga aatacctcca aaagtttctt aacggctaag gcacggtgag attgactatt
    41041 tttttcttcc agggttaatt cagctgatga ctcacctgtc tctcctacaa ggaagagggg
    41101 atcatagcca aagccatttt cacccttagg ttcaaagtta atataacctg accagtctgc
    41161 ttcaacaact aaactttcct tatttgggct ggctacgact agggttgtgt ggaactgagc
    41221 cgagcggtcc ttgagttcaa agaccatggc caattcgtgc aagagtttgg cattattttc
    41281 acggtcagtt gctcccacac ctgcgaaacg agctgaccag acgcctggta agccaccaag
    41341 gacatcgact ttgagaccag aatcatctgc caaaaccatc ttgcccgtta attgagaaat
    41401 ggtttctgcc ttaaggcggg catttttctc aaaggtcata cctgtttctg ctacttcagg
    41461 caggtcaggg tagtcattaa gattttccac atcgtagcct aacttatcaa agatagctcg
    41521 gaattccttg attttacctt cgttacgagt cgcaatcaac aaggtttctc tgactttgct
    41581 tgtctcaaag aaatcatgaa cattgacccc ttctttaggc aattctacat acaagagttg
    41641 cccattttca accaagagca gggccccatg acgttgaata acttccaagt ttcgtcccat
    41701 ttcttgatta agcatatcta ccacaaagga gaacaaacgg taggtagaac catagcgtaa
    41761 aacagtaact gaaagcggga aaccatactc ttcatctcca aatattttgg agaattcaaa
    41821 cagaggaaaa tctgtctgat agtcgctcaa actgttaacg ccaccaaaaa tactataaga
    41881 cccaacatac cagtcctggt catccttata ttcataaatt ttatttgtca taattctaca
    41941 tgctccacat gaatctcttt ttccagccat tcttcaccaa tttgtgcaaa actttggcta
    42001 ctggctgttg tgtaaaaacg gtgatggagt ggtccagcat cgcgaccacg attgatttca
    42061 aaataattga gtaagactga gatatcccgt acgcactctg ccccactatc gatgagctga
    42121 acctttggcc ccatcacatt ttggataata gggcgaagga gtggataatg agtacagccc
    42181 aaaatcaggc tatccacctt tccaaccaag ggacgcaggg tttcatagac caccttcttg
    42241 gtaacactgg ttgacagggc acctgactca accaagggag caaacttggg acaggccaag
    42301 ctctccacct gtaagtcggg atccagatca tggattttct gacggtatat gtctgattgt
    42361 accgtcatgg gcgttccaat cactccgatt ttcccacctt gactggactt gatggctgcc
    42421 gaagctcctg gcaaaattac acccaagaca ggaatatcta gttgagcctt gatttcttcc
    42481 cagacgaccg cagtcgcagt gttacaagca atgacaatca ttttgacatc cttggtcaag
    42541 agaaagttga ccagctgcca agtatattca cgaatttgct cagcaggacg ggggccatag
    42601 ggcgcccgcg ccgaatctcc aatatagacg atttcttcat ggggaagctg gcgcatgagc
    42661 tcgcgcacaa cggtcaagcc cccgacaccc gaatccaaaa aaccaattgg tcgattatcc
    42721 atacagtctt ctttctagtc ttttttctga ttgatcgttc attatgattc cttgtactga
    42781 acgaactgac cgacagcttg atagaatgtc aactacctct ctcttaatca taatcaaata
    42841 tcaatagaat gcaaggaaaa agtctcatcc ctaaaccata accaacatag tgagaagtct
    42901 ggaactttca tcccagactt ttccttattt attttttctt tttattgtta gcaagggctg
    42961 ccttttgttg gcggatgatt tggtggtaaa cttgttgtac cttagcttcg cttggttttt
    43021 gaccatttgc actcaaaaga gtacgaactg cttcagcatt caaacgtggg ttgtcagcaa
    43081 attctttttc gatttgctta cgaaccaagt acattcctcc aagagctcct cctagaaaag
    43141 ctagcacaat caatacaatt gctaaaagta aatccatcat ttttctcctg tttctttttg
    43201 aatccctttc attataccac aaactagcca ccctgaccag tttgttctac actttcaggg
    43261 atggaataga cagcaaaaag aaccctgctt ttctgaaaaa gaggtctcct tgctaagttt
    43321 atactcaatg aaaatcaaag agcaaactag gaagctagcc acaggttgct caaagcaccg
    43381 ctttgaggtt gcagataaaa ctgacacggt ttgaagagat tttcgaagag tattaattta
    43441 cataaatagc cagtgtttga tagggtttga gtagaatttt ctcagacact tctgcatctt
    43501 catagtttga tatcaaaatc tgtccatttt ggtagactgc tggcaagtcg atttccactt
    43561 ctttagcata aaagttattg agcactagta acttttgatc ctcaaactgg cgttcaaaag
    43621 cgtagacttg tttgctatct tcaaaggctg gtttgtaact tccttctgaa atgattggca
    43681 tttccttacg cagtcgaatc aagtcttgat agaaggtgaa aatcggaccc tggatttcat
    43741 tttctacatt gatgtattta taggatttac cagctttcaa ccatggagtg cctgttgaaa
    43801 atcctgcatt ttccgaagca tcccactgca tgggaatgcg tgaattatca cgcgacttag
    43861 cttgaataat ctggaaggct tcttgctgac tctttccttc ttctaagagc gtctgatagg
    43921 cattaagcga ttcgacatcc acataatcag ccatagaatc atagtctggg tcaatcatcc
    43981 cgatttcttc acccatatag atataaggtg tcccacgtga caggtgaatg ctagccgcta
    44041 gcatggtggc tccttccttg cggaagtttt gaatatcgac aaaacggttc aaggcacgtg
    44101 gttgatcgtg attgttccaa aagagggcac tccaaccgtc tttatcactc atttccttac
    44161 cccaactatg gtaaagactc ttcaactctt caaaatcaaa gggagccaag gtccactttt
    44221 gtccatcctt atagtccacc ttgaggtgat gaaaattaaa ggtcatggat aattcctgac
    44281 gatcaggcga cgaatagagg acacagtttt ccatggtggt agaagacatt tccccaactg
    44341 tcataaagct atcgtcagat ccaaaagtgg cttggttcat catacgcaaa tagttatgaa
    44401 cgatgggttt gtctgtataa gctggcttcc cttcattttc aggacagtcc actgaaacct
    44461 cgtccttacc gatcaaattg atcacatcaa atcggaaacc tttgataccc ttgtcgcgcc
    44521 agaaattaac aaccttgaaa agctccttac ggacattgga attgcgccag ttaaggtcag
    44581 cctgggtctc atcaaatagg tgaagatagt atttcccagt atccccgaaa ggcgtccatg
    44641 cagaaccacc aaacttagac tgccaatctg ttggttggtc ttggatgaag aaaaagtctt
    44701 gataatactt atcaccagct agggctttct gaaaccattc atgctctgtc gaacaatgat
    44761 taagtaccat gtccagcata aagtcaatct tgtgctcttt accgacacac accatttcct
    44821 caaaatcagc catatcacca aaaagaggat ccactgccat ataatctgaa atatcgtaac
    44881 cattatcccg ttgagggctt ggatagaatg gattgagcca gaccatatcc acacctagtt
    44941 tggctaaata gggaattttt tcgataatcc cacggaaatc cccaataccg ttttcagtgg
    45001 tgtctttgta agattttgga tagatttgat agactacttt tcctttatca agtgtcatct
    45061 gtttctcctt ttctgataaa agggaggaag cagtcttccg tccctatttg tgctatttca
    45121 attatactca atgaaaatca aagaacaaac taggaagcta gccacaggtt gctcaaaaca
    45181 ctattttgag gttgcagata gagctgacgt ggtttgaaga gattttcgaa gagtattaga
    45241 ttcgtgtagc gaccatgaga gatgctccag cttggatcgt tgtcggataa gttccgggaa
    45301 tagtcgctgt ataagcatct tggttggtga tgataacagg agtttctgtc accagacctg
    45361 cagccttaat gacatccata tcaaaacgaa tcagttgctg accaactgta acgtgatctc
    45421 cttggactac aagactttca aaacctttgc catcaagacc tactgtatcc ataccgatgt
    45481 ggatgagcaa ttcaactccc tcgtcagaga caatgccgat ggcatgcttg gtagggaaaa
    45541 gaaccgtcac tgtcccatta actggagagg tcaactcacc ttggcttggt tcaatgacta
    45601 gaccttgccc catgacacct gatgcaaaaa taggatccgt cgcttgactc aattctttca
    45661 cttggccagt tagtgggctg ataatttcta ccgaagtaag ttctactggt tcatggttca
    45721 caaattctgc ttcttcttga gcaacgaatt ctgcctgcaa gttcgtatcg ccctctgttt
    45781 ttgtaaagag accagccttg cggaagaaga aagtcaagag cattggaaca acaatcgcaa
    45841 ctagcatagt tcctgcaaat ggcagcatgt attgaggttg aatagagaga atacctggca
    45901 aaccaccgat accaatagaa gccgcagtta cattaaaagt aacggataac atgcctgcaa
    45961 gggctgaacc agtcatccca gcaacaaatg gataaatata ttttacgtta accccaaaaa
    46021 gagctggttc tgtaacaccg agataggctg aaatggttgc aggaagtgaa acctgagcct
    46081 cacgctcatc atggcgatgc atgaaataat agacaaacac ggctgagcct tgagcaatat
    46141 tagaaagagc aatcattggc catagggcag tgccaccagc atccgcaatc aattgtgtat
    46201 caatggcatt ggtcatatgg tgcagacctg tgatgacaaa tggagcgtag agggcaccaa
    46261 aaattgcacc gaagagccat ttaactggac cagttaaacc tgccaagaca actgatgaaa
    46321 gtccttgtcc aattgtccaa ccgattggtc ccaaaacagt atgagccaaa atcaaggctg
    46381 gaatcaatga caagaaaggt acaaaaatca tagaaatgac ttctgggata tgcttgcgcc
    46441 agaagatttc aagataagac agactcaaac ctgcaagcaa ggctgggata acttgggctt
    46501 ggtaaccgat acgattaaca gtaaaatagc caaaattcca aacccagttt gccgcgatat
    46561 cagctgctgg cgttgaagca accgcatagg cattgagcaa ctgaggcgat accaaacaga
    46621 ttccgagaac aattcccaaa atttggctgg ttcccatctt acgagaaaca gaccaagtaa
    46681 tccctactgg taagaactgg aagatagctt caccaggcaa ccagaggaag tgattgacac
    46741 ctgcccaaaa ctgagaggat tctgtgatgg tcttgccatc caacatcgac caatggacac
    46801 cttccaagac attacggaaa ccgaggatca atcctccgac tatcaaggct ggaataatcg
    46861 gagtaaaaat ctccgccaga gtggtcataa cacgttggac cacgttttga ttactcttag
    46921 ctgcagactt ggctgcttct ttggaaacac cctcaatacc tgaaacggct gtaaaatcat
    46981 tataaaagat gggcacgtca tttccaatga ttacctgaaa ttgacctgca tttgtaaaag
    47041 ttcctttaac agctggaatt gactcgatag ctttaacatt agccttctta tcatctccta
    47101 aaacaaagcg catccgtgtc gcacagtggg tgacggcagt cacattttct ttgcctccaa
    47161 ttgcctgaag cagatctttg gcttcttgtt caaattttcc catttgattc tccttatact
    47221 tgtcaaagca agtttgattt gataagtata ttgtaaacga taccaaactt gtctgcaact
    47281 tgtttggtat aaaaagggtg tttttttgta aattttctag cacttgtatg gtaaaataga
    47341 tacaggtgtt cattaaacta gactaaaaac ctatttaagc aggcaaaatg aagaaatacc
    47401 aacaattatt taagcaaatc caagaaacca ttcaaaacga gacttacgct gtcggagatt
    47461 tccttcctag cgagcacgac cttatggagc aatatcaagt gagtcgtgat accgtccgaa
    47521 aggccctgtc tctcctccaa gaggaaggat tgatcaaaaa gataagaggg caaggttctc
    47581 aagtcgtcaa agaagaaacc gtcaatttcc ctgtatccaa cctaaccagc taccaagaac
    47641 tagttaaaga acttggactg cgctctaaaa ccaacgtggt cagtctggac aagattatta
    47701 ttgataaaaa atcctcactg ataaccggtt tcccagagtt tcggatggtt tggaaggtgg
    47761 tccgccagcg tgtggtggat gatctggtat ccgttctgga tacagactat ctggatatgg
    47821 aactaattcc aaatctcact cgccaaattg ctgagcagtc tatctattct tatatagaaa
    47881 atggcctcaa actccttatt gattatgctc agaaggaaat caccattgac cactcaagcg
    47941 accgagacaa gattctcatg gacattggca aagaccctta tgtcgtttcg attaaatcaa
    48001 aagtctatct ccaagacgga cgccaatttc agtttaccga aagtcgccat aagttagaaa
    48061 aatttagatt tgtagatttt gcaaaacgca agaaataaaa gactgagaca ccagatctca
    48121 gcctttttcg gctctataat atttgtagtg ggtaac
//
LOCUS       DAVAGB010000013        46062 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVAGB010000013 DAVAGB010000000
VERSION     DAVAGB010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46062
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.013"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(654..2381)
                     /gene="ezrA"
                     /locus_tag="VQO19_000792"
     CDS             complement(654..2381)
                     /gene="ezrA"
                     /locus_tag="VQO19_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HET1349085.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2463..4409)
                     /gene="gyrB"
                     /locus_tag="VQO19_000793"
     CDS             complement(2463..4409)
                     /gene="gyrB"
                     /locus_tag="VQO19_000793"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HET1349086.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4424..4987)
                     /locus_tag="VQO19_000794"
     CDS             complement(4424..4987)
                     /locus_tag="VQO19_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET1349087.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(5072..5626)
                     /locus_tag="VQO19_000795"
     CDS             complement(5072..5626)
                     /locus_tag="VQO19_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HET1349088.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5637..6860)
                     /locus_tag="VQO19_000796"
     CDS             complement(5637..6860)
                     /locus_tag="VQO19_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET1349089.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6897..9347)
                     /locus_tag="VQO19_000797"
     CDS             complement(6897..9347)
                     /locus_tag="VQO19_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HET1349090.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9547..10476)
                     /locus_tag="VQO19_000798"
     CDS             complement(9547..10476)
                     /locus_tag="VQO19_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET1349091.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFFDTGFYDYDPDMVR"
     gene            10616..10903
                     /locus_tag="VQO19_000799"
     CDS             10616..10903
                     /locus_tag="VQO19_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HET1349092.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10937..12271)
                     /gene="ciaH"
                     /locus_tag="VQO19_000800"
     CDS             complement(10937..12271)
                     /gene="ciaH"
                     /locus_tag="VQO19_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HET1349093.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLEDARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12261..12935)
                     /gene="ciaR"
                     /locus_tag="VQO19_000801"
     CDS             complement(12261..12935)
                     /gene="ciaR"
                     /locus_tag="VQO19_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HET1349094.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(13044..15590)
                     /locus_tag="VQO19_000802"
     CDS             complement(13044..15590)
                     /locus_tag="VQO19_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HET1349095.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15713..16153)
                     /locus_tag="VQO19_000803"
     CDS             complement(15713..16153)
                     /locus_tag="VQO19_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HET1349096.1"
                     /translation="MTPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(16128..16997)
                     /locus_tag="VQO19_000804"
     CDS             complement(16128..16997)
                     /locus_tag="VQO19_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HET1349097.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQEFVKDYLDTICSFYLGKEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLDRILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16975..17475)
                     /locus_tag="VQO19_000805"
     CDS             complement(16975..17475)
                     /locus_tag="VQO19_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET1349098.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKARGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVISYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(17486..18184)
                     /locus_tag="VQO19_000806"
     CDS             complement(17486..18184)
                     /locus_tag="VQO19_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HET1349099.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGFQVYGVDQGENPLLEGDF
                     HFLQRDLTLDLEPIFGWCPQVDVLCNTAGVLDDYKPLLEQTAQEIQEIFEINYMTPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEVAEVSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18177..18413)
                     /locus_tag="VQO19_000807"
     CDS             complement(18177..18413)
                     /locus_tag="VQO19_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HET1349100.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(18513..19439)
                     /locus_tag="VQO19_000808"
     CDS             complement(18513..19439)
                     /locus_tag="VQO19_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HET1349101.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(19514..20329)
                     /locus_tag="VQO19_000809"
     CDS             complement(19514..20329)
                     /locus_tag="VQO19_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349102.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFLLFRGFKKIKWSEV"
     gene            complement(20333..20653)
                     /locus_tag="VQO19_000810"
     CDS             complement(20333..20653)
                     /locus_tag="VQO19_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET1349103.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLTKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(20983..22980)
                     /gene="metG"
                     /locus_tag="VQO19_000811"
     CDS             complement(20983..22980)
                     /gene="metG"
                     /locus_tag="VQO19_000811"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HET1349104.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQVYVDRMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKDHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEKSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(23104..24363)
                     /locus_tag="VQO19_000812"
     CDS             complement(23104..24363)
                     /locus_tag="VQO19_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET1349105.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKFQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(24365..25066)
                     /locus_tag="VQO19_000813"
     CDS             complement(24365..25066)
                     /locus_tag="VQO19_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1349106.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(25050..26249)
                     /locus_tag="VQO19_000814"
     CDS             complement(25050..26249)
                     /locus_tag="VQO19_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HET1349107.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVARADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            26514..27860
                     /gene="gor"
                     /locus_tag="VQO19_000815"
     CDS             26514..27860
                     /gene="gor"
                     /locus_tag="VQO19_000815"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HET1349108.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNRESYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            28057..28593
                     /locus_tag="VQO19_000816"
     CDS             28057..28593
                     /locus_tag="VQO19_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HET1349109.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            28649..28729
                     /locus_tag="VQO19_000817"
                     /pseudo
     CDS             28649..28729
                     /locus_tag="VQO19_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(28798..29013)
                     /locus_tag="VQO19_000818"
     CDS             complement(28798..29013)
                     /locus_tag="VQO19_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HET1349110.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PNHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            29111..29431
                     /locus_tag="VQO19_000819"
     CDS             29111..29431
                     /locus_tag="VQO19_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349111.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(29462..29800)
                     /locus_tag="VQO19_000820"
     CDS             complement(29462..29800)
                     /locus_tag="VQO19_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349112.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(29812..30531)
                     /gene="trmD"
                     /locus_tag="VQO19_000821"
     CDS             complement(29812..30531)
                     /gene="trmD"
                     /locus_tag="VQO19_000821"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HET1349113.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(30521..31039)
                     /gene="rimM"
                     /locus_tag="VQO19_000822"
     CDS             complement(30521..31039)
                     /gene="rimM"
                     /locus_tag="VQO19_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HET1349114.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(31070..31858)
                     /locus_tag="VQO19_000823"
     CDS             complement(31070..31858)
                     /locus_tag="VQO19_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET1349115.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADVVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDEYGPELYLKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            complement(32435..32674)
                     /locus_tag="VQO19_000824"
     CDS             complement(32435..32674)
                     /locus_tag="VQO19_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HET1349116.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(32694..32966)
                     /gene="rpsP"
                     /locus_tag="VQO19_000825"
     CDS             complement(32694..32966)
                     /gene="rpsP"
                     /locus_tag="VQO19_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HET1349117.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            33136..33345
                     /locus_tag="VQO19_000826"
     CDS             33136..33345
                     /locus_tag="VQO19_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349118.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            33824..34036
                     /locus_tag="VQO19_000827"
     CDS             33824..34036
                     /locus_tag="VQO19_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349119.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            34119..34922
                     /locus_tag="VQO19_000828"
     CDS             34119..34922
                     /locus_tag="VQO19_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET1349120.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(34978..36519)
                     /locus_tag="VQO19_000829"
     CDS             complement(34978..36519)
                     /locus_tag="VQO19_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET1349121.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(36521..37003)
                     /locus_tag="VQO19_000830"
     CDS             complement(36521..37003)
                     /locus_tag="VQO19_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET1349122.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNVLNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(37003..38088)
                     /gene="rlmN"
                     /locus_tag="VQO19_000831"
     CDS             complement(37003..38088)
                     /gene="rlmN"
                     /locus_tag="VQO19_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HET1349123.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHIMVSTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(38109..38639)
                     /locus_tag="VQO19_000832"
     CDS             complement(38109..38639)
                     /locus_tag="VQO19_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HET1349124.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            complement(38796..39401)
                     /locus_tag="VQO19_000833"
     CDS             complement(38796..39401)
                     /locus_tag="VQO19_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HET1349125.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(39574..40611)
                     /locus_tag="VQO19_000834"
     CDS             complement(39574..40611)
                     /locus_tag="VQO19_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET1349126.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKAFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(40645..41580)
                     /locus_tag="VQO19_000835"
     CDS             complement(40645..41580)
                     /locus_tag="VQO19_000835"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HET1349127.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(42133..43323)
                     /locus_tag="VQO19_000836"
     CDS             complement(42133..43323)
                     /locus_tag="VQO19_000836"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HET1349128.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(43538..44881)
                     /locus_tag="VQO19_000837"
     CDS             complement(43538..44881)
                     /locus_tag="VQO19_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET1349129.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(45261..>46062)
                     /locus_tag="VQO19_000838"
     CDS             complement(45261..>46062)
                     /locus_tag="VQO19_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000465985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET1349130.1"
                     /translation="YTPQVTEETIKVGQTPDLTDNVTNLPNLPAGTKVVDITPAGQID
                     TTKPGTYTGKVRVDYPDGSSTEVSVSVNVLPAPETQTYKVTYRFESATADNNLPAEVL
                     SLLPQSGTYTTSSSVAIAFVPEAPMPVEVAVANGTWTFLGYQEVEEGSNLTFVGKWVF
                     EAKQDPSPQPQPAPTPQPAPQPNPVPPVNPGGEQGTDNNQADRHQSEQPRKPEENPPA
                     QGPAGEKEKQATLPNAGSTAPLSLTGLVTSSLLAGLAVLLLGRKRKDD"
BASE COUNT        13610 a        10073 c         8342 g        14037 t
ORIGIN      
        1 ccctgttctt gtttcgtttt actatagaac gatttgaagg cgtttatgat atttagctgt
       61 acgagagtct tttaaaagtg ttttgatggc ttggatttct tctttagttg attttatatt
      121 actattatat aatacttttt tattttagtc tagtataaat agcgagaaat atctatccta
      181 tcttctagaa tgtcttccaa acgagaaaac tctcgtaaac aaagaggttt tagaggccta
      241 tttaccgtgg gactaaagtt gtacaagaaa agtgcaaata agaaatctcc agattaggaa
      301 ctatccgtga gttctctagt ctggagattt ttcaatagac ttcgttattg gacagttacc
      361 aagttactca aagtacagat ttgaagctgc agataagact gacgaaatca ctttaatact
      421 aaatgaaaat caaaaagcaa actaagaagc tagcctcagg ctgtacttga gtacggtaag
      481 gcgacgctga cgtgatttga agagattttc gaagagtata aaacactgtt ttgaggtggt
      541 ggataaatcg gctgggtaaa aactcaatct caggagaaaa tgaagtaaat ctccccacaa
      601 ctatagaaaa agatttgatt ctgctcctca cacaataaaa tctttttctt ttattaaaaa
      661 cgaatcgttt cacgtgtttt ctcatatgag gtaacaaagc gattggttac accaggctct
      721 gccacttcca atgcttgaga aatcttgtca aatgaagcgt gataatcaaa ttctttttca
      781 aaaatatcta aagcttcgtt aaatgcttct tgaatgcgtt catcaaatga gcgatagcgg
      841 ttagaatatt gcaagagttg ctctgtcaaa gttgcatatt gtacaatatt ataagtttcc
      901 gtttctaaag cttccatatc attcgttgca atttcaagaa ctcgggtaac agattcaatg
      961 ttaatcattt tttgttctaa ctcaaccatt aaatcctcgg tattattgct tgccgtaaag
     1021 aataacttca agaaagtttg tggaatacct ggcagattgc gtttttccat gtatcgcttg
     1081 atagtatgga gacgattgac ataaacattg gccttttgac gtgcattaat atcatctttc
     1141 tcaatttgtg tcaggcgctc actaactgaa atttgctcat cttcaatatc ttttagttga
     1201 gtttgtaaat cctcaagatt ttcttcaaga actgaataag cttgggttgg ttcttcttga
     1261 ttcgaagtta cctcaacaat agctgcctca aaactctcta attctgtctg aatacgacga
     1321 acatggcttg cagctgtctc aggaagtaaa taggtcttgt tcaaacgtgc aatatcttct
     1381 cccaataaag tattattctc tttcatatgt tgaagataag ttggaagagt tgcaagtaga
     1441 ttttccacta ctttctgagc agcaatttct cgagtaaaaa tatcatacaa ggcattgatt
     1501 tcctcttgtg cctgtccatt ctcatattcg gcattatcca attccaactg acgaatattc
     1561 tcttggtttt tcttgaatgc ttcataaagc aagtggaaac gcgcttcaat atccgtttca
     1621 acaaaatgat aattagcatc aattagttta cgataaccgg cttccaaatc ctgtaattga
     1681 tctggcaatt ctgtagaaag cgtcgtaacc aaggctggaa cacgatccac aatatgactt
     1741 aaggccaaaa tgtgattttc tgtattatcc aaaatcactg cggcttccac agggtcaccc
     1801 gatgaattca aggttacaaa ttgtgaaaat tcagattgga tattttctaa ttgtttttca
     1861 atttcatcca aggcttgacc atactgttct gaattttcag caactctatg ctgaagttcc
     1921 tcaaataaat ccaaagcatg aagaacacga ccactatttt tagattcttg cttctctaag
     1981 tctgccaaag cattgcgaat tgccgcaata tcttcttcaa tcaaagtaat ttgactctca
     2041 atttggtcaa tttgatgact ggccttgaga aaacgaaatg aatggttata gccttctgct
     2101 tcaaagagat tattttcaat atcggcaaaa gagttgagag ataaatcgac ccatttttga
     2161 ttccattcac ggaaagccac ttgactttgt ccaatcaagt gcatattttt tacagcttct
     2221 acttcatcat ttactggaag attgtatagt tcttcttttc tttcttctag cgcctctaat
     2281 ctcccctcgt ttcgcttacg tagaaagatt gccactacat aagccagaac taaaatgact
     2341 gcaattgcaa ccattaaata aattagttgt ccattagaca tatcaaactc cttttttact
     2401 tgaaacaatc gtaacgatta tatcatattt tttagaccaa gggaactact tctccctatt
     2461 ttttagacat caagtgtact atagacagca ttttcttcga taaactcacg acgaggctct
     2521 actcgatccc ccatcaacat atcaaagatt ttatctgctt ctgcagcatc atctacagaa
     2581 actctagcca tcaagcgatg ttcgggatcc atggttgttt cccacagctg atgatcgtcc
     2641 atttcaccta gccccttata acgctgaata gtcggtttgg tacgaccttc actataacgg
     2701 gctaaagctt cttggagttt gatttcttga tctgcacccg gctggatata ttctttaatc
     2761 tcgcttccaa ccttgacacc atagattggt ggttgggcaa tataaacata accagcttct
     2821 aggattggtt tcatataacg ataaatcaag gttaaaagaa gggtacgaat gtgggctcca
     2881 tcgacatcgg catcggtcat caaaacgagt ttttggtaac gggctttcga aacatcaaat
     2941 tctgcgccaa atcctgttcc catggctgtg aaaagactac gaatttcttc gttggctaga
     3001 atcttatcca tacttgcttt ttcaacattc aaaatcttac cgcgaattgg aaggatagcc
     3061 tgaaactcac ggttacgacc agatttggct gatccaccag ctgagtctcc ttcgacgatg
     3121 aagagttctg tttcagcagg gttattagaa gaacagtctg ctagtttccc tggaaggttg
     3181 gaaatttcca aaccagattt tttacgtgtg acttcacgcg cacgcttggc agccacacga
     3241 gccttggcag ccaaaattcc tttttctacg atacgtttgg caatctgtgg attttccatg
     3301 aggaaatcgg agaaggcttc actgaagagg cgattggtaa tcttgaccac ttcgctattt
     3361 cccaatttgg tcttggtttg tccttcaaac tgtggatttg ggtgtttaac tgagataact
     3421 gcagttaagc cttcgcgaac atcttcccct gttaaattat cttcattgtc tttcagtaac
     3481 ttattcttac gagcataatc attgataaca cgagtcagtg ccgtacggaa accttgttca
     3541 tgcgttccac cttcatgggt atgaatatta ttggcgaaac tcatgacatt ttcatggtaa
     3601 cctgttgtgt actgcatggc tacctcaact gtaatatcat ccatctcacc gtctgtatag
     3661 attggtgtat caaagattac atccttgttc tcgttgatat attcaacgta actagcaatc
     3721 ccaccttcat aatgataatg cttggtttgt tccaaacctt ggcgcttatc agtgatagaa
     3781 atttgaagac cgcgatttag aaaggccaac tcttgaatcc gtttatttaa tttatcaaaa
     3841 tcaaagattg ttgtttcagt gaaaatttct gggtccggtg tgaagtgaac cgttgttcca
     3901 gttctatctg tatccccaac cacctcaagg tctgcaacaa catgaccacg acggtattct
     3961 tggtaatgaa tcttaccgtt tttatggaca tgaacgtcta attgagtgga aagggcatta
     4021 actactgacg accccacccc gtgaaggcca cctgaaacct tgtatccacc accgccgaac
     4081 tttcctccag catgaaggac tgtaaagacg gtctcaacag caggacggcc tgttttttcc
     4141 tgaatatcga ctgggatacc acgcccatca tccacaacag taatcgaatc atctggctca
     4201 ataaaaactt gaatatggct ggcaaatcct gccaaggcct cgtcaattga gttatcaaca
     4261 atttcccaga ctagatggtg aagaccttct tttgaggttg atccaatgta catccctgga
     4321 cgcatacgaa cagcctctaa accctctaaa acttgaattt gactggcatc ataatcctgt
     4381 gcctgcagat ttttgatttc ttctgtcatc ttattccttt ttcttatatg tctaatactt
     4441 gtcttaaatt cacgatactg gtaaacaagt gggtatcaag tcctgcagct tgacctgctt
     4501 cgatatcaat cggccgatca ccaatgacaa gaccagagct aatctgatac ttttctctta
     4561 aataaagcat ggattcggga tttggttttc tcttaaagcc tgagctagaa gtcaccactt
     4621 ctgtaaaata agctgctata gaggtttttt ctaaaatttc caaaacctga tcatttcgat
     4681 gagagaccaa aaaatgacgg ccaccttgat ttgaaatgtc ttccaatagg tcagaaactc
     4741 cttcaaataa aatcgggtgt tcaagctctc tagcttcatt ttccttgtac ttttctaaaa
     4801 aattctctaa attgggagcg aatgtctcaa tcgcaaaagg agtagaaacc tttaaagctt
     4861 gatagacact gtcatggtct tgtgtgatac catacagtgc caatgtttca acaaatgcag
     4921 ctgttgaagt ttcataatta tccagtaaag ttccacctaa atcccagatg taatcgtgat
     4981 atttcatacc cttcattata gcattttttt atgaaaaaag cgatgatttc cctgagtttt
     5041 ccacataaaa aacgagagaa taactcccgt tttactgatt tttaccaaag acatctcgat
     5101 agagcattcc tgttcgtaaa ctctctgcgt cccctcctag ttgctccacc aactcgtagg
     5161 caaaggcaag ggctgttgaa ggaccccgac tggttgtcaa ctgaccatct accactactg
     5221 tttccttgac gtagtgacca tcaaggattt gctcttgaac gccgtcataa caagtgtatc
     5281 gcttattttt caatatctct gcttgattga gggcaattgg tgccgcacaa atggctgcta
     5341 gtttcttccc ttcttgctcg aagctttgca attcttgaat caaggtctga ttatcacgta
     5401 aatgtgcaga accaggcata cctccaggaa gaacaatcat atcatagtct gataaatctc
     5461 catcaaagac atgatctgct cttacttgga ttgcatgcga acccgttact tgctcttcaa
     5521 aaccaaccat atcacatgtg atattggctc gacgcaagac atctacaact gtcaaggctt
     5581 caatttcttc aaagccctga gctaacataa ctgctacttt taccatgatt ttctccttat
     5641 ttaatttgtt ttaatacaac ctttttccgt ttgaatggga cttttccgct cttttcttca
     5701 gctagattag tctggtaact catcgataaa agcaaaccaa caccaatcag attactgata
     5761 atagctgatc ccccttgcga aatgaaaggc aagggaatcc ccgtcaaagg aagtagtcca
     5821 gtcacagcac cgatattctc aaagatgtgg aagagcaaca tcataatcaa acctgtggaa
     5881 atataagtgt agaactggtt atttgattta agagtaatct tcaacatacg gtaaatcaac
     5941 atgagataga gggcaataac caggacagag ccaataaagc caaaatcttc tgcaataacc
     6001 gtaaaaatca tatctgactc tcgaactggg ataagcagat tcgaagcatt aaatccctga
     6061 ccaaataagc caccactccc aatggcaatc tgcccttgag cctgctggta agtcgttgtt
     6121 tgggcaaact caaagggatt gagccaagcc aaaatccgat tgatttggta ggtcggcatt
     6181 ccaatctggt gaagaaaagc tcgtccgtcc ttgctaataa agatagctaa gaaaccagca
     6241 actcctgtta cagcagtcac aaatactggg ataataattt tccaagaaac ccctgataat
     6301 aaaacgattc ctgagaaaat ggctacaaaa accaaagccg tccccaagtc actttgaagt
     6361 gctaaaagaa ctaggactgg aatggtaaag agaatcatcc agaaaattaa caaaaagtcc
     6421 agcggaaccg tgcgtctcca ttccttatgt ttctttgtaa attggacaat gacacgagcc
     6481 aacatgagga tataggatat cttcataaat tctgacggtt ggaatagggt aattccattt
     6541 attgataccc agtttttggc acccgttgat gcaactaagc ttggattata aaatacaatc
     6601 ggcaagatca taagtcccaa gcctaaaata tatagaaagg gggtcacctt ccaaagaaat
     6661 tctgtattaa agagcatgac cacaaaacca atcacaagcc ccaaggcaat ccaggcgacc
     6721 tgctgcccta aaatgggcag aatattattg ggataatcat gactaacggc tatatagata
     6781 gccaccacac cgatgaccag tagaaaaaat actggcaaga gcaaactgta atcgactctt
     6841 gagtcgagag aacgtttcat atatactaac cttatacttt catacaatac tatttatcaa
     6901 agttcattaa aaaatctatc aatagcctcg tcaacttcgg atcgagagat ggttttaaca
     6961 gtcgcttctt ctgctagaga tgctactatt tgtttgccgt atcgttttcc gacgattctc
     7021 ctatccaaaa taagagttaa ggaacgttgg tattcacgtc tcatacttct tcccaaagcc
     7081 tgttttaaac gaataatggc cattggcaat tgataatcat aaaaggcatt tttcccttct
     7141 tgattcagtt cttgattaat ctttttcgtc aagggttctt gaggattttg gaaaggaagc
     7201 ctcggtacaa cttgaatcac aaaaggatgg cttgaaaaat caactccctc ccagaaactt
     7261 gctgcaccaa gcaagatttg ttgttcacct ttttcaaagc gtttctttag ctgatgaaca
     7321 tccccatttt tatactgggc caagtggcta actgtaagta aatccgatac tgctagaagc
     7381 atgtctttag cggtaaagag aaccaaaatc ggttgctgga aagcttgaat ttccactagt
     7441 aaagcagcta cctctctggc atagacttct aaggaggttt ctgttaccag agggaaatct
     7501 ttgaccatga ccacttcttg ttcctgtttt ccccgagatt caatcttgac aaatttggct
     7561 tcaggatagc ctaaaaggtc tgccaaagaa accctctgac taatctcaag agtagccgat
     7621 actcccaaga cttggcaact ctcaggaagt aaagaggaca gaagagtacg gcctgatttt
     7681 gtagaagaaa tctgaatttt cttttgactc gtttcagtta cttcaagcca gtaatcacct
     7741 tcagctgtaa aatagcgaac cagctcatca aagccttcca cttctaattc tgaaaaatac
     7801 tgatggagat tgtccagaga atctaagata tttttcctag atttgccaga ctgaaattgt
     7861 tctatcaagt agagacactc aaagcgaata ctttctagta tccgttgttg aaccctgttt
     7921 tcttctccta ctaaagcctt atcaattaaa tcgataatag attgtatatc gtaggtctct
     7981 tgaagcagat tttctagagc taacaaaatc ttttggactt catcaataat cagtaaacgg
     8041 tcactgacaa attcaggatt atcttcaagt ctggtcacga gataggcatg attagtcact
     8101 aaaagcttgc aagtctctgc cctttcttga ctacgtttcc aaaaatcttc cgtcacaaat
     8161 aagctctggg atgataaatt cccatcatga cgaaggtctg ctagaaaatg ttggtaacgg
     8221 tagagttgcc cgatttcatc caaatctcct gtctctgtct cagtaagcca gaccaagact
     8281 tgcattttaa agcgtctaaa taagcgattt tcatcatttt cctgcaagga atgataaaag
     8341 gcatccaact tcagataatt ttgtggtccc tttaagctat gaatatctgt atggaacact
     8401 tccttgagac gtttaccttc ttcttccatg atttgatttt gaagaatctt tgtcggaaca
     8461 ctaagaacaa tttgtcgctc tttggattga gataaagcgg gtaagagata gccataggtt
     8521 ttcccaatcc ctgtcggcgc ttgaatcaga gagacaggtt catctttcaa tagcaagcca
     8581 acctctttag caaaactttc ttgttcctcc ctcacttcaa ggttcaacag agaaatattt
     8641 ttagaaaagt cttgagatag ttttcgtagc tccagagaag ctgccgtttt cttaaaatac
     8701 agaccttgaa cttggaccaa gtctggagaa ctcaggatag attggttgcg ataagtttcc
     8761 tcaataacca ggtaggactc atataggaga gcgtcagcca tttccagcaa gcgttccaag
     8821 agacctttag gaagctgggt catcttttcc cgtaaaaaaa gaagtaattc tgctgtagct
     8881 tgggcatctg aaagggctgt gtgtgcgtgt ttaagaggaa ttcctaattc tcgacacaaa
     8941 atcggcaagc tatatttttc cagttcaggg aaaaagacct gggccaattc gaccgtatca
     9001 acacgagggt ttcttagctc atagccttca aaaaataaat tttccgccaa gagattagca
     9061 tcaaactgaa cattatgggc tacaaaaatc ccatcctcca ccaagtcaaa tatttttctg
     9121 gcaacttgcg aaaaatcagg tgcttgcgcc agacgttggt ctgtcaatcc tgtcagttct
     9181 ttgatatgag catccaaggg ttcatgtgga ttgacatccg tcgtatagtg atcgacgatt
     9241 tctccgtcct caatcacgac aattcccact tggataattt tagccttact acctgtgcta
     9301 gttgcctcta aatccaccac aacatagcga ttaccaatcg ttttcattat aaaaaattat
     9361 accaaaaaaa gggccatttg gcacctgcaa acataggata attttcaaac tcaagaacac
     9421 tacttttctt aaaaatccca tcgaatagag cattctagcc tgctgatttt tgtaaaatag
     9481 tgaagaaata cgaaaaattg agagaagaaa tgtttgcatc ttccttctct caacgaatca
     9541 tgtattttat ctaaccatgt caggatcgta gtcataaaat cctgtatcaa agaaacggtt
     9601 tttagggtga agtttacgaa cttcttcatc cagcaagaag gcttgatcat ggctaaagtt
     9661 gccctcttga atcaaattac gcgcttggat aaagagtttt gcaatctcaa caaagttctg
     9721 accaggagtg tagagccctt ctagtttcca gcgagtaaag ccatgctcca ccaattctgt
     9781 taatttgatc atcaaatcaa ggtcattgtt ggcaaagata tgggtcccat gattatcttc
     9841 aaaaatggaa tagtggctct ctggatcact tggctcagcc aagaagaggt cacgtttatg
     9901 cgtcttttca tcatcgatat gtgtaaagtt atagtagttt tgcaagagtg gacgtttaga
     9961 atgatggatg acgctagcac cgtaaaccaa aacttcagca ggaatttcca aaatctctgg
    10021 cattttgaaa agttcagctg atggaatttc acgcgccaaa acagcctcag atgcgccagc
    10081 cttttgtccc cagaagttaa tctgacgact gctagttacc atggttgaag catcgtagat
    10141 ggtcttaaat gaataaccat cgcggttaac tacgtaaaag acgcctgcat ccccaatcgt
    10201 aatatagtct gtcttgattt cttccaagaa gtctaagaaa ggcttgatac ggtccatcat
    10261 atcttggtgc atgagagcat tgaccgcaac gagcaattcc ttaccagcat catgaaccaa
    10321 cttagcgatt tcacgtaatt ggtcataact aaaggtcgtt ggcagacgaa ggccaaaatc
    10381 tttctcaccg acatagatac ggtctacgcc agcttcgagt agttgttcaa cttgttcaat
    10441 actttcagca gttgctgtaa tgacaatctt ttccataaga aaaattatac cacatttctc
    10501 caaaatcagc catgctttga aaatgaaaag ggactttatt ctttttgtaa cctttctgta
    10561 ataattctct gccgaaaaaa tgataaaata ggtatgtact gttaaggaga gaatcatgcc
    10621 cgtaagaaaa ttacaatcct atgaggtaga ctatcaagaa gaattaaacc agcagcttcc
    10681 tcattaccaa gcttatacac ctgaagcgca atctgatgcc aatctcaagg aaatcctatt
    10741 ttttattaat atcgctgttt tttgtatctg tattgctatc tttagtttta tctttttagc
    10801 attaaaatta tcaactgctc ttgcctttgc cgcagcaatc ggattcagct tacttgtttt
    10861 aaaagttcaa cggtctatta tcaaacgaaa acgtagaaga tagatccaaa atatcgcccc
    10921 aattggagcg atatttttat tttttctttt tagatggtgt ctgaatggca atcttcactt
    10981 caaagattgt tcccttgggt ttattatctt tgacagtaac agttcctttt agagcatcta
    11041 caatttgctt ggctagggat aatcctaaac caaaaccacc tttttgccgg gttctagctt
    11101 tgtctactcg ataaaaacgg tcaaaaattt tctttttatc ttctgtcgaa ataccgattc
    11161 cattatcaga aacaagtaaa taaagattgc gatcggtcgc cgagataaga aaatcaattt
    11221 caccatcctc ctcagtatac ttgacggcat tatcgaaaag aatggtcatc agttgtttca
    11281 gaagaagctg atctgtgaca attgttcgat ggatacgatt ttcaaaacgg aagacacgat
    11341 tattttccga agcaatcatc tcgtagtttg tgaaagttgt attaaaaaag ctagttggaa
    11401 cttctgcaag ctccggctta atcccatcat ctctccgagc taagttcagc aagcttgtcg
    11461 ttaaaaaacg catatttcgg acttcttcca aactcgatgc aatgctttcg ctcacatcca
    11521 taatggtagc ttctggctta cgaaaaaggg tctctaagcg attttgcaaa actgcgagtg
    11581 gagttcgtaa ctcatgactg gcattttcca caaaagactg ttgcttctgc atactctcaa
    11641 gcaggggcct aacactgacc ctagctagat agagactggc aagtaaagac aaaatccaga
    11701 aactagccat cacgaccaca atcaattgct catgcttttg actagcctgc tccaactgac
    11761 tggtattaat caagacagca gcatacttta tattggttga aaccgaacta atattggtct
    11821 ccatcaaaat cacacgatag atttcttcct gcccatagct attaaaaacc tgaatctggt
    11881 agatatgtcc tagttctttc ttttctaact taatcttatc caagcccaaa aatcgatttc
    11941 cagaaagaag ttgagtaaag tctttatcaa agagaatgac ttccgtattg gaactgacat
    12001 taggttttat ttctacttta ctagcgtccg ccctagcatc ttctaaatct ttaatctctt
    12061 ctgttgccct atttatagcc agctgaataa ctgcttgagg attttcactc agtccatgaa
    12121 gcttatcgtc caccgaagta taaagactcg aatgcatgac ttgtaaaata atcagagtca
    12181 ttgtagaaaa aatcagggtg aagacaccga agttacggat aaaataacta aagtcatccg
    12241 cataccatgt ttttttaagt ttactgaaca tcttttaaaa gatacccaac actacgcaag
    12301 gtttgcaaat tctctgcaaa agtggttccc tttaatttct tacggacttt tgaaacatag
    12361 acttcgacaa ccgaaatcgt tgtatcacta tcaaatcccc atagacggtc aaaaatctgc
    12421 gtcttaggca aaatcacatt ttgattttga aggaaataaa ctagtaaatc gaactctttc
    12481 cccagcaatt cgacaggagt atcttcaact ttaacggtat tggttgataa attaaccacg
    12541 atattcccat aagtcaaggt gttttcatta aacttccctg aacgtttgag aagggcctga
    12601 atccgcattt taagttcttc taggtagaaa ggtttggtca gataatcatc cgctcccagt
    12661 tcaaatccat gtcccttgtc atccaaactt tccttggcag tcataatcag aactggtgtc
    12721 gtaattccct tttcacgcaa ttcttttaag acttggaaac catttttttc tggcaacatc
    12781 aaatccagca aaatcaagtc atagacacca ctctcagctt cgtagagacc ttcttctcca
    12841 tcaaatacct gcataacatc cgcaaaatcg tctaaaaagt caaatactga atttgacaga
    12901 cctaggtcat cctcaaccaa taagattttt atcatgagaa actcctcctt attaaaacta
    12961 ttataccaaa tttgccttaa aaaaaactca actctctgca ttttacatga gatagctgag
    13021 ttttcttttt attttaggct tatttatgca tttccgtatt gaagaacaac tgcttcgact
    13081 gcagcttttt cacggctaat caagtcaaca cgtgctgcaa tttccttgat tcccataccg
    13141 atgttacggc taagagcaag gtcagaaagt tgcggctcaa agaactcctt gtattccgcc
    13201 aagcgttgct gagtcttaaa tacatgagca ggaaggataa caaagctatc aaagctcata
    13261 tctcctccaa gggctgcctt aatccaagcc cagttttcac gcgcccaaga ccaagctgtt
    13321 ttctgagttg cttgatgagc taggaattga taataccaag cagacaagtc ctgtggtttg
    13381 accacaaatt tgtccttcca agaagtaatc aagttttgga tattatccgc atctgtactg
    13441 tatgcaagag ctgctgccaa ctggcgttta aagacagcat ctgttgcgtg agtataagta
    13501 tcaagataaa gtgctaacaa gtctttagtc tcatgatgtt tcatctcatt aatcagaact
    13561 tgtgaacgaa tagctgctgg gagtcctgca agattctcct tgtgtgttgc gaagatttgg
    13621 ctagcgactt gactagcttc tgcatcattt gagcgaatca tcatcgaaac agccagctga
    13681 cgaaccaatt catcctcatc tgattctccg tctttagctt caaaaccaag acggtcatag
    13741 ttatgacgag ccaatttagc aaccagtcct ttgaaggctg tttcagcatc cgttccttca
    13801 tcaataaagc gctcaagggc tgaaatcact tgagaaacag ctgaaaccac cagataagac
    13861 tcttccttag caagtttatc aagaactgga agcaagtctg cataagaaat gtgccctgcc
    13921 tcagccaaca aacgacgttc ttgaacaatt tgcagtttgc ttgtgttatc aagtgtctct
    13981 agctcagcaa gaacagcttc taacaagtct ccttgatagt cggtaatata gtgggcagta
    14041 ttttcagtgt tgagacgaag agctccttca ttttcagcaa gaagagctgc gtagccaggg
    14101 atttcgatac tttcagtttc gagtgtatca ggcaagcctt tccagttgct attgaggggc
    14161 accacccaga gacggttctt gtcttcgttc tcaccgatga agaattgttt ttgtgaaatc
    14221 ttcaagacat cattttcaac tttgacagta agaactgggt aaccaggctg ttccaaccaa
    14281 gaatccatga aggctgcgac atcacgtcct gacgcttgac caagggcatc ccaaaggtca
    14341 ctaccaatgg tgttgctgta ttggtgtttt tcaaagtagg cgtgcaaacc tttagcaaaa
    14401 tcagcatctc ctagccaacg gcgaagcatg tgcatgagac ggcttccttt ggcatagacg
    14461 atagcgccgt caaagagtgt attgatttca tctggatgtt taacttcgac gtggacagac
    14521 tgaacgccat cagtagcgtc acgttcaaga gcaagaggta ctccacctgt ttggaaatct
    14581 tcaaagatat tccagcttgg ttcgatggta tccacacaga cgtattccat catattagcg
    14641 aaactttcat tgagccaaag gtcatcccac catttcatag tcacgaggtt cccaaaccat
    14701 tggtgagcca attcatgggc cacaacaagg gcaacttgtt gacggctagc aaatgtagag
    14761 ttctcatcga caaccaagta aacttcacgg taggtcacaa gaccccagtt ttccatagca
    14821 ccagctgaga agtcaggaag ggcgatgtgg agagattgag gaattgggta cttaactcca
    14881 tagtaatctt cgtaaaactc gatagagcga acagcgatat ccagtgagaa atcaagattt
    14941 gaaagtggat gtgctttggt tgagtagaca cctaccaggg taccattttt agttttagcg
    15001 gtcacccctt gcaaatcacc agcaacaaag gccaacaagt aagaagacat gcgaggtgtt
    15061 gtctcaaact tccagatacc tgtttcctta cggttttcaa catcgatttc tggcatgttt
    15121 gacaaggcca attcaccttc tgcttggtca aagcgaagag agaggtcaaa agttgctttg
    15181 gcttcaggct catccacaca cgggaaagct tcacgcgcaa aatggctctc gaactgagta
    15241 gacaagacct ccttcttgac tccatcaact gtataataag aagggtaaat ccctgtcatg
    15301 ttgtctgtaa ttttaccaga aaaggcaaga accaattcaa cttgaccagc ctcagccaat
    15361 tcgatatgaa gggcttcatt gtcatggtca actgtaaatg gacgagcttg acctgcaact
    15421 tctacagagg tgatttccaa gtctttttgg tggagggaga tgcggtcact ctgtgcttga
    15481 ccagtgatgg tcactttccc agaaaaagtc ttggtctcac gactcaaatc taaaaataaa
    15541 tcataatgtt caggaacaaa ttgcttaata aaatgttcaa ctgcttgcat agttttctcc
    15601 tattctaagt ttaagagctg ctgctcttct tcaaacaaac ttattatatc atattttgct
    15661 tgagaaaaaa ggattggaca gcgatttcca aaactttctt ccttctaata gtctacagtg
    15721 ggtagacctt gcgaaattct tctaaaacaa ccttgctttc aggtgtaaaa gtcagcccta
    15781 cttcacccaa acagtctgtg aaaaagtcct catgaacctg gcgccaatag gcaagtgatt
    15841 tgtctccctc accttcctta aaggcatgtt gcgcagaaac ttgattgaag agttcaacag
    15901 aaacctttgt aatttcgaca atgcagacag cctgattttg actatctaaa atgacatcga
    15961 aggtccctac ttggggaagt ggttcgtctt ctagtacata gaggtcatag gctgatgctg
    16021 ttgctgtctt ttctccttta aacaccaaat ccgctaaaag gtctggttca actccaaaag
    16081 cccaagcatc gatttcatct ccgatcaaag gattgatttg cttgtattta ttccacattt
    16141 cttgcggtgt catgggtact cctttgtaat tttttacttt cttcttttat gtgtttaaga
    16201 tgatctggat ggtcaatctc taaatcaaaa atctctggaa tagaactgta gtggataatg
    16261 cacttgatac ccaactgatt cattttttgt atgaaagaag tattcagata gcctgctaca
    16321 gcaaaattaa tcttgttctt tcttgcttta tcctgcatat ctcttagcat atctaacatt
    16381 attggacttt ccatatcatg ccattgactg tttctcatag tcgcaaaaac aaaggaagtc
    16441 aaatcattca ttccaactac aatctttgaa atgcccgttt ccagtatcct atccaagtca
    16501 aaatacgctg acggtaattc aatcatcgtt ccgactttcc cagtaaagcc atactgacgc
    16561 aatactgtaa tagcttgttt taattggtcg gcatcattga caaaaggaaa gataagagat
    16621 agattgggat tggtttgata aacttctgta acgacatgtg cttcagcctg aaattcatcc
    16681 aaacacgcca gtaaacgcct ggttcctcta tagccaaaca agggatgccc ttcgtcaaaa
    16741 aactctctag tccccactaa acaattggct tctgtattcg ttaattcaga aaaacgatac
    16801 caaacttcct tacctaagta aaaggagcaa atagtatcaa gataatcttt cacaaattcc
    16861 tgacaacttg ctaatatgat gttttgatta agctctctca acaaatattc cccacgaatc
    16921 atgccgacgt ggtgaaatag ttgaggataa attttttcaa gaattttttc gccactaagg
    16981 gcaagttgat ttctcatcat tcaccttcca attcatgtaa gaagtcttgt ccagttctgg
    17041 aaatcctaat aattcagact taaccttcaa gactaatggc gatgcatttt cttctgtaat
    17101 ctcttgaata tccatccaaa tatatccaag tgaatcattc gcaccatcag acacagcttc
    17161 cgaagtcgta acttgaggtg cactctcatt catttcaaca tcatacaagg ccatgacatg
    17221 gtgaaccata aaattggtta actcttctct gacgaaaaca tcgtagattc gaggattaga
    17281 gtagcttata acagtaaatc ccgtctcttc cataacttct ctagtcagcg tttccgtcag
    17341 tccttcacca agttgctgac tgcctccagg tagatcatac cgatgttgat aagggcctct
    17401 cgctttttca atgcagagta acttcccatt ttctaagcaa acagcgtaga ctccaaagtg
    17461 ttttttgatt tccatccaac tcctcctact tcaaagacca gccaccatct attgtcaaga
    17521 tttgtccttg catggcagat gcctttccac tggccaaaaa gagactgact tctgccactt
    17581 cctctggttc aatccagcgc ttgattggtg tttcactagc cacccagtca gctaagccac
    17641 ctggctcaaa atccgcagcg gtcatagccg tcttgactgc tcctggagca atcccaaaga
    17701 cctgaatccc agcttcagca tagtctagag ccaactgctt ggtgaagcca gccaaggcat
    17761 gcttggatga agtataggcg tgaccacctc cacctgctag gctagaagca atggaacaca
    17821 tattgatgat gattcccttt ttattttcca gcatttgtgt caaataatac cgagtcaact
    17881 caacaggagt catgtagtta atttcaaaaa tctcttgaat ttcctgcgca gtctgttcca
    17941 acagtggttt gtaatcatcc aaaactccag cagtattaca caaaacatcc acctgagggc
    18001 accagccaaa aataggttcc aagtccaagg tcaaatctct ctgtaaaaaa tggaaatcac
    18061 cctctaagag tggattttca ccttggtcaa ctccataaac ttgaaagccc ttctctaaaa
    18121 agagtcgagc ctgagccaat ccgatacctg aactcactcc tgtaataagt acacgtttag
    18181 tcatgcactt ctacccaatc cgttgccaaa acatcacaag ctgtcgggct ccacatggaa
    18241 aaaccttctc cttcgccaga aacgttgatt aggaaataag gtgtcacttc aagtgcaagc
    18301 ccgttttgtt caatggtgtc aaaaagttgg acatagtttt ccgcacctcc ccaaccagtt
    18361 cgtacatatt ttttcttagc ctttaagcca ggtagaattt cttcaaatgt catgtttttc
    18421 tcctttaatg tcaataattc tccccttcat tataacaaaa aaaccgcttt aaaacggctt
    18481 tttgactgtg atttatttac atcttcttct acttacggca aattattccc tgcagcaaga
    18541 taaatttcat accattcttt tcttgttaag ctaaagtttg ccgctcggct aacttctctc
    18601 aagtgcttag gatttgttgt acctacgact gcctgcattt ttgctggata acgcaatatc
    18661 caagaaatgg caatagttga agaggttact ccatatttaa tagctaaacg atcaagtact
    18721 tgatttaaag cttgaaattt ctcatttcca acaaagttcc ctttaaaata cccgaattgc
    18781 aagacagacc atgcttgaat gaccacatcg tgtaatttgc aatattcaaa aatgctgcca
    18841 tctcgcatag ctgcttgact atcttccata ttaacatgaa aagctgattc aaatcctgga
    18901 gtaaaagccg cactcaattg tagctgatta acagctaacg gctgcttgac atctttttta
    18961 agcaactcca tcatcatagg attttgatta gaaactccaa aatctcgaac cttaccttgt
    19021 ttataaagga gatcaaaggc ttctgctact tggtcagatt ccatcaaagc atctggtcga
    19081 tgaaggagca agctatctag atgatcaatc ttcaatcttt gcaaaatacc gtctactgat
    19141 tttataatat agtccttaga aaaatcaaaa taggtaaatt cttcaatgcg aatgccacat
    19201 ttggactgaa tccacatctt ttctcttaaa tctggacgat tttttaggac aagacctaac
    19261 agttcttcac aacgaccacg accataaata tcagccaagt cgaaggcatt gattccaaca
    19321 gaaagtgctg tttctacaag ctcttcaact tcttttacag acttatcttt tattctcatc
    19381 attccgagaa caatttctga taattctttg tcatcttgac caagagttat gtatctcatc
    19441 aaatttttct cctttaattt ctaacattct tcccttcatt ataacaaaaa accgctttgc
    19501 aacggctttt tgactatact tcactccatt ttatcttctt aaacccacgg aacaagagaa
    19561 aaatgccaat aaagaggaca gctaaaggaa taacttttgt aaggaaaaca tttgaaattc
    19621 ccatccactc ataataacgg agcagagaac ccaccacaag atgggcaata atcatactga
    19681 caaatggacg aaagaccgct tctttccaat tccaaatacc gataactagc gaaatcgtaa
    19741 agacagacaa actatcccag ggagccggaa tataaaaggc tccttcttgt atgaagcttg
    19801 ccattcctac atatcctaaa acaactagaa gaactatagt cccaacaaca atgtaagtgc
    19861 caattttcat tttaggagaa tcttggacta aacttcttcg taaaattgtg gccacaagtc
    19921 caaatccaat cagaaaaata agaagttgcc ctaaaaatgt gagcaaattg actgttaaga
    19981 gaggaccttt agaaaaatca cttagtagtt gataataacg taataccgcc aggacaagaa
    20041 ttggcgtcaa aagggactct ttgatagaac tgcgaggtgc tcccttgaga atctctttca
    20101 ttattttttt aggattctta cctagataat cctctgcact catgccatct cgttctgctt
    20161 ctgagaaatc tagcatcatc aaatagatct gctctctgag atagtcttca tcatagagaa
    20221 atccagcaag attaaaactt tcccacaact cctcaaaata cttttgattc tcctcagaaa
    20281 actcatgtag caaagcgctt gtttcttcgt aatacttcat tttcttcatg gtttaacccc
    20341 cattcttaat cccttctact ttttgactca aatcgtccca ttgctgccaa aagactgaga
    20401 cacgctcttc tccttctttc gttaatgaaa aatacttccg atctggacca tctggcgacg
    20461 ggcgcatgtc gcctcttatc cattgatttt tttctaactt ttgcaacaaa ggataaatag
    20521 ttcctggaac gatagtatca aatccagcct ctcgcaaagt ctgaaccaac tcataaccat
    20581 accgctcttt ttgaccaatc atatccaaga cacaaccttc aagaacacct tttaatagct
    20641 gagtttcttt catcacttct cccttctaat ctattttgta atacctacta gtaacttcac
    20701 ctatagtata ttacttctac actagtttgt aaagcataat agttaatact cttcgaaaat
    20761 ctcttcaaac cacgtcagcg tcgccctacc gtatgtatgg ttactgactt cgtcagtttc
    20821 atctacaacc tcaaaacagt gttttgagct gacttcgtca gtttcatcta caacctcaaa
    20881 gcagtgcttt gatcaacccg cggctagctt cctagtttgc tctttgattt tcattgagta
    20941 taaataaaaa acagaactag cctgaactag tcctgtctac ttttacccaa tcacacttcc
    21001 atttggtaca gctggatcaa ctgtgagaag ggttaatttg ccatcatgtt cagctgagag
    21061 aatcataccc tggctgacat attttttcat cattttacgt ggtttgaggt tagcaacgat
    21121 ttgaactttc ttgccgacca attcttgttc atttggatag tattttgcaa ttcctgaaag
    21181 aatctgacga tcttctccat caccagcatc caagcggaat tgaagcaact tatctgaacc
    21241 ttctacttta gacacttctt tgacttctgc aacacggatt tcaaccttgt caaagtcttc
    21301 aaacttgatt tcatccttgt ttagtttgag ctcaacttcg tccggattcc attctttttc
    21361 gactgctggt ttattgcctt ccatttgttc cttgatatag gcgatttctt cttccatatt
    21421 tagacgtgga aagataggtg ttcctttggc aactacagtc acatctgctg ggaagtcagc
    21481 caaactcaag ttttcaagac tagaaacttc ttccaaacca agttgagtca aaactgcacg
    21541 actagtttcc atcataaatg gttcaatcaa gtgagcaact acacgaatgc tggctgccaa
    21601 gtggctcatg acacttgcca attggtcacg aagagcttca tccttggcca agacccatgg
    21661 tgcggtctca tcgatgtatt tattggtacg agagatcaga gtccagactg cttcaagcgc
    21721 acgtggatag tcaactgctt ccatgtgtgt atggaagtct gcgattgatt tttctgcaac
    21781 ctcagcaaga acatgatcaa attcagtcac accttctaca taggcaggga tttgtccatc
    21841 aaagtactta ttaatcatgg aaaccgtacg gttaaggagg ttcccaaggt cattagccaa
    21901 ttcatagttg atacgaccga catagtcttc aggagtaaag gttccgtctg aaccaactgg
    21961 aaggttacgc atgaggtagt aacgaagtgg atctagtcca taacgctcta ccaacatttc
    22021 agggtaaacg acattccctt ttgacttaga catttttccg tctttcatga caaaccaacc
    22081 atgggcaatc aaacgatcag gtaatttaac atccaacatc ataagaagga ttggccagta
    22141 gatagagtgg aagcgaagga tgtcttttcc taccatatgg aagactgttc cattccagaa
    22201 cttgtcaaag ttaccatgtt cgtcttgagc gtagccaaga gctgtcgcat agttaagaag
    22261 ggcatcaatc caaacgtaga caacgtgttt tggatttgat gggacaggca ctccccatgt
    22321 aaaggttgta cgagataccg ccaaatcttc caaacctggc tcgatgaagt tgcgtagcat
    22381 ttcattaaga cgaccatctg gcgtgataaa ttcaggatga tctttgaaaa attcgaccaa
    22441 acggtcttgg tatttgctaa ggcgaaggaa gtatgattct tcagaaaccc attcaacctc
    22501 atgacctgat ggagcaatac caccagtcac atttccagct tcatcacgga aaacttctgc
    22561 cagctggctt tctgtaaaga attcttcgtc tgatactgaa taccaaccag agtattcacc
    22621 caagtagata tcatcttgag caagtaagcg ttcaaagacc tgtgcgacaa ctttttcatg
    22681 gtagtcatca gttgtacgga taaatttatc gtatgagata tctagtaatt gccagagttc
    22741 tttaactcca accgccattc tatcaacata gacttgaggt gtaataccag cttcttccgc
    22801 tttctgctgg attttctgac catgttcatc aagacctgtc agataaaata catcgtagcc
    22861 catcaggcgt ttgtaacgtg ctaggacatc acatgcgata gttgtgtagg cagaaccgat
    22921 atgaagtttc ccagatggat agtaaatcgg cgttgtaata taaaaattct tttcagacat
    22981 aatttttcct ttccaggcaa atgaaacctg tttttctaac acttcattat atcacatttt
    23041 taatgaattt cgatagggaa atccatacaa aaacaagata gacgagtatc catcttgttg
    23101 atcttattca taacgaaggg cttcaattgg atcaagtttc gatgccttgt tggctggcaa
    23161 gactccaaaa atcataccaa cactagccga aactgcaaga ctaaataggg caactgggat
    23221 tgatactcca acttctatac cttctattaa accttgcagt aacaaacctg ctaaggcagt
    23281 taaaccactt gcaattgtca agccaattaa gccacctaac aaggtcaaaa tcatggattc
    23341 aatcaaaaac tgaattaaaa tattggcacg tgttgcaccc aaagccttac gaagaccaat
    23401 ctcacgagtg cgctctgtca ccgaaaccag catgatgttc atgacaccag ttcctccaac
    23461 aaagagagaa atccctgcga tggaactaat aatcgtcgtc ataaaactaa acgattgttg
    23521 aatttctgca aatacaacgg actcatctgc cacctggtat tctccctgtt gtaagcctgc
    23581 aagctctgtc atttttcgtg ccagttctgg acccagagtt ggggttaaac tggtatcatt
    23641 cactcgaaag acaatattag ctatttcatc tacattaaaa ttcgcagcaa gggagatatt
    23701 ggtagtaata ggcaagccac caaacccata tatttttgat cttttagcct ccggactagt
    23761 ataaacccca atgacccggt aactaaatcc attgacttct acaaccttgt taatagcctc
    23821 ttgaggagat tcaaataaac taatggacaa ttcctcatct agcaaaatga cacttgcaaa
    23881 ctctttgaaa tcttgctctc tcagactacg acctgcaata atttcattct taacagcgtc
    23941 catgtaagtt ctgtttccac ctgtcaaatt agcattctca acctttttat cttgataggt
    24001 caagatggca ttcgttgaat tggttacata gtaactatcc actcccttca gtttagctgc
    24061 ctcttgaacc caggattctt gcggttttgg cggttcaaca ggaacttcct cttcctttcc
    24121 agaaaccgta aaagctgatt gtttctgagt aaaagaccca tctttacttt ttttaggaga
    24181 gaaaaagacg ctaatatttt tctgaaattt agtcatatct ttattgactt gacgagatag
    24241 ggaatcaccc aaagccataa tcacaacaac tgatgaaaca ccgataataa tcccaatcat
    24301 agtaagcaaa gaacgcatct tgtgagccat gatagatgaa aaggcaaatt tcagattctg
    24361 catcttagtt ttcctccttt cctaactgag cactgtcaga cgaaatgacc ccatcccgaa
    24421 tgacaatctg acgtttggca taggcagcaa tctcaggctc atgcgttacc atgataatgg
    24481 tttttccttc tttattcaaa tcaaccaata attgcataat ttggttacct gttttggtat
    24541 ccaaggctcc tgtcggttca tccgctagga taatagaagg attgtttacc aaggcacgcg
    24601 caatggctac acgttgcttt tgaccaccag ataattctga aggtaaatgg tgactacgtt
    24661 ctgtcaattc aaccttgtct aaatattcct cagccaactt gcgacgtttt gaagacgaaa
    24721 ctcctgcgta aatcaagggc aattctacat tttgcagagc attgagcttc gatagaagaa
    24781 agaactgctg aaagacaaaa ccgatttgtt ggttacggac cttagccagt tgtttttcac
    24841 caagcccagc cacttcttga ccttcaagat aatattctcc actggttggt gtatccaaca
    24901 tgccaatcgt attcatcaga gtggacttac cagacccaga tggtcccatg atggctacaa
    24961 attcaccctc attcacttct agattgatat ttttgagaac ctgcagttct tggtcaccat
    25021 tacggtagct tctgaagata ttttttagac taattagttg cttcatcagc cttcacctct
    25081 tttccttctt ccaaggaaga tgttggatta ctgatgacct tagcaccatt tgtcaaacca
    25141 gaagtgattt cttgattttc tgcgtcagca tttcccaatg aaacctcaac ttttttagcc
    25201 ttttgttgtt catccacaat ccagacataa tttttactat catccattac tagactgcta
    25261 acaggaacaa gaatagcctt agttttgctt ttaacctcaa tgttgacaga aaaaccttgt
    25321 ttcaaatcac caacctcgcc tgtcacatca atagtataag ggtatttaga acctgtatta
    25381 ttcccggctg ctggactagc tgcttcacca ttgtttttag gatagtcaga aatatagctt
    25441 aatttcccag tccatttttt atcaggatac actttagaag taaagcttac ttcttgacct
    25501 acagaaaggt tggctagatt gtactcagac aattctccct tgacttgtaa attttcattg
    25561 ctgacaatat gaaccataac ttgactcgcc cctgttggag atttagaaac attgctattg
    25621 acttcgacca cagttccctc tagggtactg agaacagttg ttgcatccaa ttgactttga
    25681 gccttgctta attgcgccgc agcatctgca cgcgcatcac gggcatcacc caattgagcg
    25741 tcaatagaag caacagaatt tccagccact ggagttgggc tttgcaccgt tgcatcttct
    25801 cctcctactg gcgctggtaa ctgtggagcc ggagctgaag cggcttcatt tcgtgcttga
    25861 ttgagttcat tgatatgacg atctgcccta gctactgctc gactagctga atcataggcc
    25921 gcctgcgctt ctgaactact gtacttgact aaagcctgcc cttcgctgac cttatcgccc
    25981 acagaaacaa ggatttcatc taaatcaccc ttactagcat caaaataaac atattgttca
    26041 ttttttgctg ttactgtccc tgacaataaa acagaggagg ccacgcttcc ttccttggca
    26101 acaacaagat gagtaggctc atcttttaga gcagtctgag aaggttgtct aaagagtaaa
    26161 atccccccag cacccaatac aactacactc gcagcaccga ttgctgcata cagttgccac
    26221 tttttagctt taccattctt tttcttcata atgaaactcc ttttcttttt tacaatactt
    26281 tgctattata ccaaatttcc ctccagcaaa caatacagtt caggattaaa caatcgttcg
    26341 gaattttgct tttctattgt actagatata taatacacta tcttgactta tttggcaagc
    26401 ttttttgcaa ttttttgtgc gtagcagatt tttgcaatca aatcaaaaaa agaataaaat
    26461 ataactatca aaaaagacgc tctactattt aaaagattac aaaggagttt tcaatgagag
    26521 aatatgatat cattgctatc ggtggaggta gcggaggaat cgctaccatg aaccgtgctg
    26581 gtgaacatgg agccaaagca gccgttattg aggaaaagaa attaggtgga acctgtgtca
    26641 acgtcggttg tgttcctaaa aaaatcatgt ggtacggggc acaaatcgct gagactttcc
    26701 atcaatttgg agaagactac ggctttaaga ctactgatct taactttgac tttgcaaccc
    26761 tacgtcgcaa tcgtgaatcc tacattgatc gcgctcgttc ttcttatgat ggcagtttta
    26821 aacgcaacgg tgtagacttg attgaaggtc atgctgaatt tgtagattct catactgtaa
    26881 gcgtaaatgg tgaactgatt cgtgctaaac atatcgtgat tgctacaggt gcccatccaa
    26941 gtattcctaa tattcctggt gctgagctag gtggctcttc tgatgatgta tttgcctggg
    27001 aagaacttcc agagtcagtt gccattctag gcgctggtta tatcgccgtt gaattagctg
    27061 gcgtactcca cacttttggt gtcaagacag atctctttgt tcgccgcgat cgtcctttac
    27121 gtggttttga ttcctacatc gttgaaggtt tggtcaagga aatggaaaga acaaacttac
    27181 cacttcacac tcacaaagtc cctgtcaagt tagaaaaaac tactgacggc attaccattc
    27241 atttcgaaga tggtactagt cacacagcta gccaagttat ctgggctaca ggtcgccgtc
    27301 caaacgttaa gggcttgcaa cttgaaaaag ctggagtgac tctgaacgaa cgtggcttta
    27361 tccaagtgga tgaataccaa aatactgttg ttgagggaat ctatgctcta ggtgatgtaa
    27421 cgggcgagaa agaactgact ccagttgcaa tcaaggccgg acgtacccta tctgaacgtc
    27481 tctttaacgg aaaaactact gcaaaaatgg attactcaac tattccaact gttgtctttt
    27541 cacaccctgc tatcggaact gttggtttga cagaagagca agctattaaa gaatacggtc
    27601 aagaccaaat caaggtttat aaatcaagct ttgcatctat gtactctgct tgcactcgca
    27661 accgtcaaga atcccgtttc aaactcataa cagctggttc agaagaaaaa gttgtcggac
    27721 ttcatggaat tggctacggc gttgatgaaa tgattcaggg atttgccgtt gctatcaaaa
    27781 tgggagcaac caaggctgac tttgatgcaa ctgtggcaat tcacccaact gcatctgaag
    27841 aatttgtaac catgcgttaa tcgaaacaaa agaagctgat ataaatatgt ctgcttcttt
    27901 tttaatgatt ttcgaatcaa caaaaaaatt atccaacttg actagtcacg aaaatcggct
    27961 gttacagttt ttgttacctt gtttttaaaa aatggttgac atcgactcct atatgagtat
    28021 aatagttact atacattaga aaagaggtta actattttga aaaaagctca cgtttatgct
    28081 atccctgcta ttggggctgc tctcattgct gttttggcac aaatcagtct tccaattgga
    28141 cctgttccct tcactctgca aaactttgca atcggcttga ttgctactgt ctttagaccg
    28201 agagaggctg tactttctgc tggactctat cttcttctag gtgctatcgg tcttcctgtc
    28261 tttgcaggag gtggagctgg ttttcaggct ttagttggcc ctactgcagg ctatctttgg
    28321 ttttatctcg tttactctgg acttacttcc tctctaacca acagcaagag tggtgttgtt
    28381 aagatttttc ttgcaaacct cttgggtgat gcccttgtct ttgtcggcgg gattctcagc
    28441 ttgcatttcc tagctggaat ggcatttgaa aaagctcttg ttgtgggggt tcttcccttt
    28501 atcattccag accttggcaa acttctggct attagtttta ttagccgtcc cctacttcaa
    28561 cgccttaaaa atcaggctta ctttactaac taaaaaagga taccgagtta tcatgactca
    28621 atatcctttt ttttattttg aaaacttata ctcaatgaaa atcaaagagc aaactaggaa
    28681 gctagccgca ggctgctcaa aacactgttt tgaggttgtg gatgaaactg acgaagtcag
    28741 taaccataca tacggcaagg caaagctgat gcggtttgaa gagattttcg aagagtatta
    28801 gttgccttta aaggcatcca ccatcgtttg aaattcttca tttgagagag taatcccttt
    28861 gcccatttta gtatggtttg gactccaagc acgaatatca aactttgcag gggcaccatt
    28921 aaagctcaca cggttaattt ccttggtcca acctttttcg ttttcagaaa gagtcaacaa
    28981 gtgctcttcg atttcaaatg taaattctgc cattttcttc tcctttttta gtttcattag
    29041 tttattcgta aaatcttgta gattttagga aaattttata taatattgat ataaaataag
    29101 ggaggccaat atgagacata aattccagca agttctagat aaaatacatg attttttaaa
    29161 tggacatgac caacctgacc agactgaaac caactccctt acagccacta ttgaagaggc
    29221 tatccagaaa caaaccgctg ttcaccttat cttgtctgag acaagtttta caggtgatat
    29281 catcaaatat gatcagcaag gccagcaaat tatcgtgaaa aattttgcca aaaatgtgag
    29341 ccggattatc cgtataagcg atattcaacg cctgcgattt gtcccctcaa ctgtccaaac
    29401 agcccaaaaa aatagattta agaaagagtg agatgtagtt gcttcatccc actctttttt
    29461 cttagcgaat ttgttcaaaa tgtaaatgaa ctgcaatatg atctccataa ccacttcttt
    29521 ccaagtcacg ttgtaaacga taggaaatgt agtgttctgc aatagtaatg taacctgcgc
    29581 ccaataaacg atgttcaacc atagattgaa tcatactgat agtcgcacgt tccaccttgg
    29641 cttcttgtaa atccaaaact accttcttag tgacttgagc aagattttga cgcaaatcat
    29701 ctgtcaaaac ataaacagtt tgggctgcct tcaagatggc ttggtaaatc ttatctggat
    29761 taaattcagc aatttcgcca ttacgtttga ttacttgcat aggtttctcc tttattcttt
    29821 gttttctttg atttctgcca gcattttttc ttcttctact gtcagttgat aatgttcaag
    29881 taaatccggt ctgcgctcgt aggttttctt taaactctcg tacaatcgcc actgacgaat
    29941 cttttcatgg tggccactca tcaatacatc tggcacgacc atgcctcgat aatcataggg
    30001 acgtgtgtac tgaggatatt ctaaaagacc tgaagaaaaa ctatcatctt ggtggctaga
    30061 ctccttgcca atcacttctg gaatcaggcg aactgtagca tcaatcatgg tcatagctgc
    30121 caattctcca ccagtgagga catagtcgcc tagggaaatc tcatctgtta ccaaggtctt
    30181 aatgcgctca tcataaccct catagtgccc acagataaag attagctctt cctcttgagc
    30241 caaatcttca gcataagcct gatcaaactg ctttccagca ggatcgagga gaataacgcg
    30301 cggatttttc ttttcaatag catcaaagga atcgaaaata ggttgtgctc tgagcaacat
    30361 gccctgaccg cctccgtagg gctcatcatc tacatgacgg gccttttcag cattttctcg
    30421 aaaattatga tactggatat ccaagagccc tttttctcga gcctttccaa cgattgagtg
    30481 ctccagtgga gaaaacatct ctggaaagag ggttaaaata tcaatcttca tcgtctaacc
    30541 cttctaagat ttccacatcg acccgtttat ttggaatatc aacattgaga accactggtg
    30601 ggatataagg taaaagcaaa tcacgtttgc cttttcgttt gaccacccag acatcattag
    30661 cacctggttg caggatttcc ttgatggttc caaccaagct atcaccctca tagacttcca
    30721 aaccgataat ctcgtgatag taaaattcac catcgtctag gtcattcaaa tcttcctcag
    30781 cgaccttgag actgtatccc ttgtactttt cgatagtatt gatatggtac atatctttga
    30841 atttaataat gtcaaagttc ttctgtttac ggtggctagc gatggtcact gtttggacaa
    30901 actgatcttt ttcatcaaac aaagccagct cagctccttt tttaaaccgt tcttctgcaa
    30961 aatccgtcac agacaagact cgcatctcac cctgtaatcc ctgcgtatta acgattttcc
    31021 caacattaaa gtagttcatc ttgtctcctg taatctcctt ttttccatct tattctgaca
    31081 attctcgaat aatagccgca attttttccg attctgacca ttgtaaataa tggtgattcc
    31141 ctcctaaaat gagtttagta ttggaagtcc aatattctga ttctctgtac tctttttctc
    31201 tataaggctg acaaaaaaca aatacaggaa tatgagcttc tatagataca tcctcaaaat
    31261 cttcctcagt aatctctcca gatatctgaa attctggatc ttgattttcc aactctaagc
    31321 ctttttcttg cattaattcc cagatttttt tattcgtttc aggactaaat gttgcttgag
    31381 ttaaattctt caaataaagt tcaggtccat actcgtcaat cagcctcatc tgctcttcca
    31441 tttctggata aggattttct gaaaaatcag caaacatgac ttttttagtt gtcggttcaa
    31501 ttgctactaa agtctgacac ttaattggtt tctcgagtaa tttgcaagct aaaattccac
    31561 tccaactatg tgcacaaagt atatattcag aaatccctaa ttcttcaagt acttcataaa
    31621 ccacatctgc aagattatct agattttttc cagcttggtc atgaatcgga ctcctacctg
    31681 tgttcggaaa atcaattgtc aaataaccaa ttgtaggagg aggtttttca agtataagtg
    31741 aaaaattttc ataacttggt agcaaacctg ctccgtttag acaaactagc actttctttt
    31801 gcttttgata agtaacagag aggctaccaa tttctgtaga tacttcaaac ctcttcataa
    31861 agaaatccac tcattctata taatgaatta ttaaaaatcc ttatccttta ttttatcacg
    31921 ttccaaggat tttctcaagt tggaggaagg ggacaacatc tctactttcc cttcaagaat
    31981 ccttccaaat catgtttatg ttggtaatta acgactgcgg ttttgtcttt ctcaaagaca
    32041 gtcttggtaa ggtcaatatg cttgatagca gcaatagcga cggtgtagta aatgatatca
    32101 gccagttctc tggcaagttc ctcgttcgaa tcctatccct tcttttcgac cagagcgcct
    32161 attcaaaacc tcggctactt ctccgacttc ctccactaac ttcataaaga gaccttcatc
    32221 agtccgagac tgctgttaat gttcgagtaa gtagtcttgg aattgcctaa acgttcaatc
    32281 ttttatagta tattgaaact agaatagtac acctttactt ctaaaacatt gttagaaatc
    32341 gatttgactg tcctgatcga tttgtcctgt tcttgtttca ttttactata tcttctattc
    32401 cacacaaaaa agcgagacat ccgtcccgcc cttcttattt ttcgtcaata acgattctta
    32461 cttttttgta ttcagttggg acagagtaga caatcgttct tatcgcagaa atagtgcgac
    32521 ccttacgacc gattacacga cccacatcgc tttgatcaag attcaaatga tattccaaaa
    32581 attctggtgt atcctcaatc ttgatagtta aggcatctgg ttgtgaaatt aagggtttca
    32641 caatcgcaat aatgagattt tcaatcgtat ccatctgtca acctacttta aacttatttt
    32701 gaaaatttag aatcgtggaa ttttttcaat acgccttctt ttgaaaggat gttacgtact
    32761 gtgtctgaag gttgagctcc attagccaac catgcaagaa cgcggtcttc tttcaaagtt
    32821 acttggtttt cagcaacaag tgggttgtaa gttccaactg tttcgatgaa acgtccgtca
    32881 cgtggtgaac gtgaatctgc tacgttgata cggtagaaag gttttttctt agaacccata
    32941 cgagtcaaac ggattttaac tgccattttt aaagtctcat ttctttaatt ttttatttcg
    33001 gtgaaatagc tgagctattt agcacatgtt ctattatagc agatttctgg catgtgtcaa
    33061 gaaaaaaact tgacagacta taaatttctt aaagtattta gaaatttgtt agaataggaa
    33121 ataaatgttt gaaagatgct atccgtgaat actattttag aaaaatttta taaagaacac
    33181 caagtcaaac ccttcatatc gcctgaacga gagttggata cttggcttct aagtcccaag
    33241 cccgttccca agcgaaatat ggacttatta gtagatgatt cactagcagg agatatcatt
    33301 ttactatgga gaatccagtt tggtactttt accactgaaa catgatttta aaaactccca
    33361 ttcgaatatg attcaaaatt cgcttagaat caatgttttc ccactttttc aaaaaataaa
    33421 ttttcatcta atttaaataa ctttcaatta agtgtgaatt ttgcttaaaa tcattaaaaa
    33481 acaccccatg gtgtgaacca tgaagtgttg taaatgctgt gttgtagcta gttcttagcg
    33541 tttagagaac tggctagctt tacgagcttt cttaagatct ggtttccaaa atactttgag
    33601 tacacttatg gtattgatgc ccctaaacat ctaaaaactc tggtagaaaa agggtatgct
    33661 cttgtcgaaa cttcttttga ctcacttgac catctaaata ataccatgaa aaagaatatc
    33721 ctgaagaaga agggagttac tggactttct aaaatgaaat cttgcgacct ggatcaagcc
    33781 cttcatgagc atttttcaga agaagaatta gctggtcact ttcatgtcct tctatggact
    33841 tttttacaat ggcattgcta tcacacccaa tacctatcta agcgcctggt tcgtaaactt
    33901 tattgcagct cttcctctaa atttcctaat tgttgaacca attgcccgtt ttatactaag
    33961 ttcttttcag aaaccattta ctggggaaga agttgaagat tttcaagatg atgatgaaat
    34021 cccaactatt atctaagcca gttctgtaaa ctactaatat ttgaaatcca cttcctttta
    34081 gggtacaatg gtataaatga atttttgaga ggatcagaat gaaaaaacta gcaacccttc
    34141 ttttactgtc tactgtagcc ctagctgggt gtagcagcgt ccaacgcagt ctgcgtggtg
    34201 atgattatgt tgattccagt cttgctgctg aagaaagttc caaagtagct gcccaatctg
    34261 ccaaggagtt aaacgatgct ttaacaaacg aaaacgccaa tttcccacaa ctatctaagg
    34321 aagttgctga agatgaagcc gaagtgattc tccacacaag ccaaggtgat attcgcatta
    34381 aactcttccc taaactcgct cctctagcgg ttgaaaattt cctcactcac gccaaagaag
    34441 gctactataa cggtattacc ttccaccgtg tcatcgatgg ctttatggtc caaactggag
    34501 atccaaaagg ggacggtaca ggtggtcagt ccatctggca tgacaaggat aagactaaag
    34561 acaaaggaac tggtttcaag aacgagatta ctccttattt gtataacatc cgcggtgctc
    34621 ttgctatggc taatactggt caaccaaaca ccaatggcag ccagttcttc atcaaccaaa
    34681 actctacaga tacctcttct aaactcccta caagcaagta tccacagaaa attatcgaag
    34741 cctacaaaga aggtggaaac cctagtctag atggcaaaca cccagtcttt ggtcaagtga
    34801 ttgacggtat ggatgttgtg gataagattg ctaaggccga aaaagatgaa aaagacaagc
    34861 caactactgc tatcacaatc gacagcatcg aagtggtgaa agactacgat tttaaatctt
    34921 aaaaaccaaa aaaatacagt atccacattc ggtactgtat ttcttttact ctcattctta
    34981 agttaaatta ttaaaatccc atatttggtc tatccagcct tcataaaagt ctggctcgtg
    35041 gcagaccata aggatagatc ccctatattc tttgagagcg cgtttgagct catcctttgc
    35101 atccacatcc aaatggttgg tcggctcgtc cagcactaaa acgttgtttt cacgattcat
    35161 caagagacag aaacgaacct tggcttgctc tccccctgat aatacttgaa tctggctttc
    35221 aatatgtttg gttgtcaaac cacaacgggc aagggctgca cggacttctg cttgattaag
    35281 ggcaggaaag gcattccaga cagcttcaag aggagtttgg cgattaccac cttctacttc
    35341 ctgctcaaaa taaccaagtt ctaaataatc tccacgctcc acttccccag cgattggcga
    35401 gataatgcct aagagactct tcaagagagt tgtttttcca ataccattag caccaataat
    35461 cgcaaccttt tgattgcgtt cgaaggtaag atttaaaggc ttagtaagag gacggtcgta
    35521 accaatttgc aagttcttgg cttggaagat aaagcgccct ggtgtacgag ctggtttgaa
    35581 atcaaaggat ggttttggtt tctcactttg gagttcgata atatccatct tatccaattt
    35641 cttttgacga gacatagcca tattacgagt tgcaacacgg gctttattac gagccacaaa
    35701 gtccttgagg tctgcaatct ctttctgctg gcgttcgtag gctgcctcta gctgagattt
    35761 cttcatagca taaacttctt ggaactggta gtagtcacca gagtaacgcg tcagctgttg
    35821 attttccaca tgatagacaa tattaataac gtcattgagg aatggaatat cgtgcgaaat
    35881 gagaacaaag gcattctcat agttttggag atagcgcttg agccaatcaa tatgctcagc
    35941 atccaagtag ttggtcggct cgtccaacag caagatatca ggcttttcaa ggagaagttt
    36001 tgccaaaagc accttggttc tttgcccacc tgacaaagaa gttacatccg tatccatgcc
    36061 aaagtccata acaccaagag cacgcgctac ttcgtcaatc ttagcatcca aggtatagaa
    36121 atcacgactc tccagacggt cttgaagttc tcctacttct tccatgagag catcaacatc
    36181 cgcgccgtct tcagccattt tcatatagag gtcattgata cgagcttcag ctttgaaaag
    36241 ctcatcaaaa gccgtacgga gaacatcacg caccgactgt ctttcagcaa ggacagagtg
    36301 ctgatccaag taaccagccg tcacatattt ggaccactca acctttcctt catctggcag
    36361 cattttacca gtcacgatac tcataaaggt tgattttcct tcaccattgg caccgaccag
    36421 gccgatatgt tctcccttga ggagacggaa ggacacatct tcaaaaattg cacggtcacc
    36481 aaaaccgtga ctcagatttt taacttctaa aatactcatt ttaattcctt atcttgtttt
    36541 tatgtaatcg tttataaagg agccaagcca gatagccacc caaagtattg gtccacaaat
    36601 catcaatctc aaagacgcga ttgaaatcaa agaaaaagtc caagattaat tgcgtacact
    36661 cgattccaag actcacaaga aaactaaaaa gaaggacctt ttttgttttc cgcaaatttg
    36721 gaaatagata aaggagttgg aaaatcagag gaaaaaacaa gaagacattg aggacatttt
    36781 gtaaaaaaat ccaacataat tgtccaatgt cactcacttc gcccagtttc cagagagaat
    36841 tgaaaggagt caaaagaaaa accaggcgtc caagatgctg aatacctgga gttcccactc
    36901 ccacggtaga ttgttcttga ggagtaaagc aaaaacagac aatgcaaatg ctatagaaaa
    36961 tgactcccca gaccaaaata tgattataag tcttcttcat cattaaggat ttaccgctgc
    37021 gactgccttc tggcggtcac gtttcattgt gttagagcgc aattgtccac aagctgcgtc
    37081 aatatctgta ccatgctctt gacgaaccac acagttgacc ccttttttct taagcgtatc
    37141 atagaaagcc aacacgcgct ctttgggact acggctatat tggtcatgct cactaactgg
    37201 gttataagga atcaagttta cataagacaa tttcttgatg ttcttgagca attcagccaa
    37261 ttccaaggct tgttctacac cgtcgttgac ttcattaagc atgatatatt caaaggttac
    37321 acgacggttt gttgtctcaa tgtagtattc aatagcagca aagagttttt caatcggaaa
    37381 ggcacggtta atcttcatga tacttgaacg aagttcattg ttgggtgcgt gaagagacac
    37441 ggcaagattg acctgaaccc cttcatcagc aaagtcacga attttatgag ccaaacctga
    37501 ggttgaaacc atgatgtgac gagcaccgat agccattcct ttatcatcat tgatagtacg
    37561 aaagaaattc aagacattgt tgtaattatc aaagggctca ccgattccca tgacaacgat
    37621 atggctgacg cgttcatcct gaccacgctc atcaaagtat ttctgaacca gcatgatttg
    37681 cgctacgatt tcaccgttat tgaggtcacg ttgcttctta atcaaaccag aggcacagaa
    37741 ggtacaaccg atattacagc cgacctgagt ggtcacacag acagataaac catagtgttg
    37801 acgcatgagt acagtctcaa ttaacatacc gtcgggcaat tcaaagagat atttgactgt
    37861 accatcagca gactcttgca caatacgttg tttcaaggga ttgaccacaa actggtcatt
    37921 gagcttagca atcaaatcct tggaaaggtt ggtcatttct tcaaatgact gcacacgttt
    37981 acggtagagc cattcccaga tttgatctgc acggaatttc ttttctccct gctccaatac
    38041 ccattcctgc atggtttgat gtgccaaact atgaattgag ggtttcattt cttctcctta
    38101 ttctctactc acttctgacg aatgacaaaa tgacgttgtc ccttgtcctc tttctgagaa
    38161 tgctggtctt tctgacgacg tctattcttc ttatctgcat tcgactttcg tttagtttga
    38221 gtcggtttct ttccttttct agaaggtgtt tcttcttccg tcttacgcat tttcttgtca
    38281 aatgatgctc gcttaggggc ttcattttct aagacaaaat aggcacaacc ataactacaa
    38341 tactctaaaa ggtagtcttg taaacgactg attttttcaa gtttttcttc tgttcggtca
    38401 tccttgtaaa aacctcgtag gcgaagctgt tcgttgctcc agtcccccac gatataatca
    38461 aacttggtta atacttctga aaaacgctga ttaaaagtcg tcacatcaaa ggcatccttg
    38521 atattttcaa ccaaggaaaa agctatccct tccgtttcga ccttgtcccc gtgtaaatgg
    38581 aactccggac caggaaactt gttatagttg tataattcag gtgcaatttc ttttcgcata
    38641 gatatccttt tttcacgatt acttaatact ttattctacc ataatttcta gcagttagca
    38701 cgtttctcat aaaaatgaaa aaagtctaac gattttgtca gaccagaatc ttataaccta
    38761 aaaaagagaa gaacaattct tccctccaac tatcattatt tagcagctgc gtacaattca
    38821 tctactttat tccagttgat tactgaaaag aaagctttga tgtagtcagg acgcacgttg
    38881 cggtatttca cgtagtaagc atgttcccaa acgtccaagc ccaagattgg ttttttacct
    38941 tctgagattg gtgtgtcttg gtttgctgtt gaagtcactt caagttttcc ttctttgttg
    39001 acaaccaacc atgcccaacc tgaaccaaaa cgagttgttg ctgctgcagt gaaggctgct
    39061 tggaattctt caaatgaacc aaatgttgca tcgattgctg ctgccagttc tgctgaagga
    39121 gctgttttct cgggagtcat caattcccag aaaagagcgt ggttcaagtg tccgccacca
    39181 ttgttgataa gtgcttgacg gatatcagct gggatagatt ctacatcagc aagcaaggct
    39241 tcaaggtctt caccgatttc agggtgtttt tctaaagctg cattggcatt gttgacataa
    39301 gtttgatggt gtttgtcatg gtgcaaatgc attgtttccg catcgatgta tggttccaaa
    39361 gcgtcgtatg catatggaag ttctggtaag ataatagcca tctgtaatac ctctttttct
    39421 ttctatatga aaatgataac gcaaacattc acttttttca agttttttgc ttatagataa
    39481 ggaaatcact gacatacttt ctaataaaat aagcaaatca gcaagaaacc cacgacaaga
    39541 taatcctgat gcgggttgta gtttcaacaa atgtcaattg acctgactag caatctgtaa
    39601 gagtgccttt tcaaaaagga aacctttttc ataaagacct gtcttaatct gatagtctgt
    39661 ctcaatcaaa taggaaatag cttgcttcag aaagctcaaa gaaagtcctc tcgaatctct
    39721 taatgcaaac ttgatttgat aaggatttgg gttacgtccc agataactac ctaaactact
    39781 tgcaatctgc gattctgttt ggccagactc cgccaaaatc ttcacctgag taaaagtccg
    39841 aaattgtccc agcatgactg caatcagttt gatttcatct tccccttgca aggtcaagtc
    39901 tctcaccaaa tcgcgcgcct gatccatctt tttagtcaga ataaactgag ttaaatcaaa
    39961 aatattgtcc tgcaaggtct tgggaattgc gttaacaata tcctcttcct cgataacaga
    40021 atccgcctta taggactgta aaaagagaag atttttctgg atttcgctaa attgaaaccc
    40081 cgacttgatg aggagatttt caaaagaatg attggtaaac tgcagacctt gtttctgact
    40141 ccacttttgg aagtactggc gcaattcttg ttcttttact tctactgcat cgaaggcctt
    40201 ggcatcacgc ttaagtaatt tgactaaccg tcttttgcta tccagctttc cttctgcaaa
    40261 gattatcaac ttggttgttg gagaaggatt gtcaaggtat tcctcaaatg acttaagctc
    40321 atcatctgtc aaaaagcgtt tcttagcagt cgtgatatcc ataaaataat ctaatatcac
    40381 gattttctca tccgcaaaga aaggaaggct gaccaactcc agttccacat ccttgtaaac
    40441 tacttctttc atatcaaagt aggcaaagtt gaggtcagca gaatcatacc caatctgttt
    40501 caacacttga ctcttcatca cttcaaactg cccctgatct gtccctgtaa ataggctcag
    40561 gctcggtaaa tttgataaag tcaacttctg actttcttca atggctagca tcgtctctcc
    40621 tttcttcaga tttttcgatt taatttagtc aatatagcgc aatttcccac ggaaatcttc
    40681 taagctctcg tagccttttt ccaccatgat tgctttcagt tcattggtaa tgcggtcaaa
    40741 agcactgacg ccttctttgt gaagggtcgt tcccacctgc accatacttg ctccacagag
    40801 gatgtgttca aaggcatctc gaccagtcag aacgccacct gttccgataa tttggatttg
    40861 aggatttaaa cgttgataaa aggcgtgaac attggctaga gcagtcggtt tgatgtattc
    40921 tccaccaatt ccaccaaaac cattcttagg ccgaataacg acagattcgt cttctatata
    40981 gaggccgttt ccgatagagt taacgcagtt gacaaacttg agcggatatt tgttgaaaat
    41041 agctgccgct tgatcaaagt gaacaatatc aaaataaggt ggcaatttaa ttccaagagg
    41101 tttggtgaag taagcaaaca cttctgccaa aatccggtct gttgtctcaa aatcataggc
    41161 aatctgaggt ttacctggaa catttggaca ggaaagattt agctcagtca gaccacgaaa
    41221 atcactctct tggacttttt tcaaaatagt atgggtttcc tctggagaca tgccgaccag
    41281 agataagaag aaagttcggt tcgactcttt ttcctgcaaa tctaaaagat aatccaaata
    41341 atagtctaag ccattatttg gcaagcccat agagttgatg gaaccaagtg gaacatcttg
    41401 gtagcgtggc tcaggattcc cctgacggaa gtccaaggtc gctgtcttag taacaaaggt
    41461 tcctgccgct gagtttttga cctcttctaa ctcctctatc gtcatacaag ccacacctgc
    41521 tgcattcatc aagcaattgt caaactcaaa accagcaatt tgtgttttcg ttgataccat
    41581 gattctaatc ctccagattt cttttattgc taatattata ccataatttt aattctaggt
    41641 ttactagatt ctgtggttct atctatttat tcggaaaaga aagtctagta cagaagtcat
    41701 gctatgaaaa cagctagtat attggaagtt tgaacaaggc ttgggtaaca gacttttgaa
    41761 tgaagtccaa gcaacaagga gaaatctcaa ccatgagtcc attccatgac tctgttgctc
    41821 tagaaaacct tgcaatagtc aagtgataac gaataaaact ttggattgaa atatctccat
    41881 gattatctat tacgaggaga aatctcaacc tttatcattt ttaaagaaat atagtaaaat
    41941 gaaacaagaa caggagaaat cgatcaggac agtcaaatcg atttctaaca atgttttaga
    42001 agttgaagtg tactattcta gtttcaatct actatacatg taaatctcta ctttcgcaaa
    42061 atggattttc agaacagtat cccaatatag ttaaaaacta taaaaaagag aggacgttcc
    42121 cctcttaaaa tcttatttta ctgcttcttt caaagcatct accttatcca aacgttccca
    42181 tggaagatca atatctgtac gtcccatgtg accgtaagcc gatgtttgac ggtaaattgg
    42241 acgcttgagg tccagcattt ggataatccc tgcagggcga aggtcaaaga tttgacgagc
    42301 cgctttttca agttgacttt cagctactgt tcctgtaccg aaagtatcga tacgaacaga
    42361 aacaggttgc gcaacaccga tagcataggc caactgcact tctgccttct tagcaaggcc
    42421 tgctgcaacg atattcttgg caatatagcg agccgcataa gaggctgaac gatccacctt
    42481 agtcgcatct ttaccagaga aggcaccacc accatgacga gagtagccac cataagtatc
    42541 tacaataatc ttacgaccag tcaaacctga gtccccttga ggaccaccga ttacaaaacg
    42601 acctgtcgga ttgataaaga attttgtctt atcatcaaga taagaagatg gaataacttc
    42661 tttgatgacc ttgtcaatca catcttgatg gatttgttca ttagtggcct ctggatcatg
    42721 ctgagtagaa ataacgactg tatctacacg taccggacga tcattttcat cgtactcaac
    42781 tgtaacttgt gattttgcat ctggacggag atagctaatt tctccagact tacgaagttc
    42841 tgccagacga cgaaccaatt tatgactgag tgcaattggc aatggcatga gctcttctgt
    42901 ttcatctact gcaaatccaa acatgagccc ttggtcacct gctccaatca agtccagtgg
    42961 atcttgatca gcatttccac gaacctccaa ggcttcgtta acaccttgag cgatgtcagg
    43021 agattgttcc accaaagatg ggtgtactcc caccgtctca gcagaaaatc catattctgt
    43081 attggtataa ccaatctctg caatggtatc acgaaccaca cggttaatat ccacataggc
    43141 atttgtagaa atttcaccaa aaacgtggac agaaccagta tatacagctg tttcagcagc
    43201 aacgtgcgcc tctggatcct ttgctaaaat agcatccaaa atcgcatctg aaatttggtc
    43261 tgcaatctta tccggatgcc cctcagatac agattcagac gtgaataatt tacgttctga
    43321 cataaaaatg tcccccctta aaaaatattg ttatagagtt acaaagtact gataggaaaa
    43381 ctctttgtaa taaataccta ccatcttatc gggactatat aactttatca ttataccatt
    43441 tttaatcgca atttgcagtc tttaatgtag tgtttcggtt tagatagttc gttctcataa
    43501 ataaaaaagt tggagctcaa tactccaaca atttctatta aaatgtttgg cgtttagctt
    43561 tacgctctgc acgaccgcga gcgcgatttt cagcacgctt ggttttacgg cgcttttcat
    43621 caaccgccca ttgaattttc ttcttataac ccggtttgac ttttttcttt ttctttttaa
    43681 ccaaaccaat catttcgata tcaagtttat cttgtttttt ctcacggtta gcacgacgat
    43741 cacggtcata ggtatcttga aattccccgt ctttgaccat cttaggacta aacttgattc
    43801 ccaatttctc caactcacgg atatccgagt catcacttgg ctgataaagg gtaatagctg
    43861 tacctggtag gccatttcgt ccagtacggc caacacggtg aacaaaaaaa gataagtctt
    43921 gcggaatggc atcattgatg acatggctga caccttcaat gtcaatccca cgcgctgcca
    43981 aatctgttgc gacaatatac tcaaaatcca gattttgcac ctgattcatg attcgcttgc
    44041 gttcacgagg ggcaatatcg ccatggattt ttgcaacctt caagccttga gcagtcagat
    44101 atgaatgcaa ttcatcagca cgcgttttag tgttaacaaa aatcattgcc aaatacggct
    44161 gcatcaactg agtcaactgg taaatttgag cattcttatc atgtcccttg gtcgaaatca
    44221 accaattatc aatggtgtca gaaataaccg ttttagtctt aattttctcc ataacaggat
    44281 ttgataagta ttttttcaag aatggttgca gtttttgtgg gatagtcgct gagaagacca
    44341 tgaattgcaa gtcttttgga agactgccag caatcttatc aacagtttcc aagaatccca
    44401 tatccaaggt catatctgct tcatcaacaa caaatgtctt ggctttatga atagctaaat
    44461 caccagattt aaccaagtcg tagatacggc ctggtgttcc aataacaata tgaggctgat
    44521 tgcttgccaa tttctcaatc tggcgagcct tatccgtacc acccacataa ttaaccacac
    44581 gaacttcgac atctgagtga gctgaaatct gacgcgctac ttggtaaatt tgagtagcca
    44641 actcacgact cggtgcagta atcactgctt gtacactatc gctagcttca tctaattgct
    44701 ggaaaatcgg taacaagaaa gtgtgagtct tacctgaacc tgtttttgat tctcctacta
    44761 ggtcacgacc tgccaaaaca ataggaatca acttgtcttg cacctctgtt ggagttgtaa
    44821 attttaactc cttcaaggct tctctaatat agtttttaaa ttgaaatttc gtaaatgaca
    44881 taacatcctc gattctatct atcttatcaa ttataccata ttttgaacat tttcagtagt
    44941 ccgactcatc tgacctatca caaggctctc aatttctcta aatatagtaa aatgaaataa
    45001 gaataggatg aatcgatcag gacagtcaaa tcgatttcta acaatgtttt agaagcagag
    45061 gtgtactatt ctagtttcaa tctactatac ctctcttata ctaaaaatca tacatttgct
    45121 ttctttccaa aatgcaaaaa gagaagacca aattggtctt ctctcagcct taaagcttgc
    45181 gactcagata gatttgtcaa acagtcaaac agttgcttaa gaatcttgta aaagtcgaaa
    45241 gcttctagaa aaattagtac ttaatcatct ttccgcttgc gaccaagaag caacactgct
    45301 agacctgcaa gaagagagct agtcactagt ccagtgagtg aaagtggtgc agtactaccc
    45361 gcatttggca atgtagcttg tttttccttt tctcctgctg gaccttgagc tggtggattc
    45421 tcttcaggtt ttcttggttg ttctgattga tgtctatctg cctgattatt atcagttccc
    45481 tgctctcccc ctggattcac tggtggaact ggatttggtt gaggtgctgg ttgtggcgtt
    45541 ggtgccggct gtggttgtgg actaggatct tgcttagctt caaagaccca cttaccgacg
    45601 aaggttagat ttgacccctc ttccacttct tggtaaccta agaatgtcca tgtaccattt
    45661 gcaacagcaa cttctacagg catcggtgct tctggaacga aagcaatcgc tacagaagaa
    45721 cttgtagtat atgttccact ttgtgggagt aagctcaata cttctgctgg caagttgttg
    45781 tctgcggttg cactttcgaa gcggtaagtc accttatagg tttgagtttc tggtgcaggc
    45841 aaaacattaa ctgatacaga cacctcagta gaagaaccat ctggatagtc aactcgcacc
    45901 ttacctgtgt aagtacctgg ttttgttgtg tcaatttgac ctgcaggtgt aatatcaact
    45961 accttagtgc cagctggaag gtttggcaag ttcgtcacat tatcggtcaa gtcaggtgtt
    46021 tgtccaacct tgatagtttc ttccgttacc tgaggcgtat aa
//
LOCUS       DAVAGB010000014        35671 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVAGB010000014 DAVAGB010000000
VERSION     DAVAGB010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35671
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.014"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            453..1496
                     /locus_tag="VQO19_000839"
     CDS             453..1496
                     /locus_tag="VQO19_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HET1349131.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            1663..3750
                     /gene="topA"
                     /locus_tag="VQO19_000840"
     CDS             1663..3750
                     /gene="topA"
                     /locus_tag="VQO19_000840"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HET1349132.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEVASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            3856..4215
                     /locus_tag="VQO19_000841"
     CDS             3856..4215
                     /locus_tag="VQO19_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HET1349133.1"
                     /translation="MRLIYLIIGFLSLTLAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYILMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4308..4940
                     /locus_tag="VQO19_000842"
     CDS             4308..4940
                     /locus_tag="VQO19_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HET1349134.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGTLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQLEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            4984..5640
                     /locus_tag="VQO19_000843"
     CDS             4984..5640
                     /locus_tag="VQO19_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HET1349135.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPQVHMESMTGSFVASVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            5659..6753
                     /locus_tag="VQO19_000844"
     CDS             5659..6753
                     /locus_tag="VQO19_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HET1349136.1"
                     /translation="MNFQLAKYSLLKKFSENIEFTAPEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAGNAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVYKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNAAGLDFDVLKASA
                     IVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            6765..7802
                     /gene="leuB"
                     /locus_tag="VQO19_000845"
     CDS             6765..7802
                     /gene="leuB"
                     /locus_tag="VQO19_000845"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HET1349137.1"
                     /translation="MAKKIVALAGDGIGPEIMEVGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAWPPLPDETLKASREADAILLAAIGSPQYDGAVVRPEQGLMALRKELNIYAN
                     IRPVKIFDSLKHLSPLKLERIAGVDFVVVRELTGGIYFGDHILEERNARDINDYSYEE
                     VERIIRKAFEIARNRRKIVTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPISMILSVVMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            7799..8068
                     /locus_tag="VQO19_000846"
     CDS             7799..8068
                     /locus_tag="VQO19_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HET1349138.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            8072..8431
                     /locus_tag="VQO19_000847"
     CDS             8072..8431
                     /locus_tag="VQO19_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HET1349139.1"
                     /translation="MAGSSREHAAWALANYGFKVVIAGTFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDHVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            8650..8793
                     /locus_tag="VQO19_000848"
     CDS             8650..8793
                     /locus_tag="VQO19_000848"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349140.1"
                     /translation="MTSDKAGLERKFAAKERKRNKPGVVLCGSMDELCALAQLNPEIE
                     AFY"
     gene            8812..9066
                     /locus_tag="VQO19_000849"
     CDS             8812..9066
                     /locus_tag="VQO19_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349141.1"
                     /translation="MLLGCILPWKPEAFEKLKAYGDGREELMTDVRGTSCFVIKFGKA
                     GEQLAAKLWEEGKMVYASYASMTKRLKLAMRARCNGVYGR"
     gene            9056..9217
                     /locus_tag="VQO19_000850"
     CDS             9056..9217
                     /locus_tag="VQO19_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349142.1"
                     /translation="MVDKDGKLIPEQGGARSTSPAPVVIRKGLDIDKIMMHLSDTFNS
                     WDYRQREYY"
     gene            9382..11313
                     /locus_tag="VQO19_000851"
     CDS             9382..11313
                     /locus_tag="VQO19_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HET1349143.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFSHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     PQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFDLTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            11300..12616
                     /locus_tag="VQO19_000852"
     CDS             11300..12616
                     /locus_tag="VQO19_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HET1349144.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNPLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRSHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIENQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASSYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            12791..13777
                     /locus_tag="VQO19_000853"
     CDS             12791..13777
                     /locus_tag="VQO19_000853"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HET1349145.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMVMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            13841..13912
                     /locus_tag="VQO19_000854"
     tRNA            13841..13912
                     /locus_tag="VQO19_000854"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13874..13876,aa:Arg,seq:ccg)
     gene            14095..14793
                     /locus_tag="VQO19_000855"
     CDS             14095..14793
                     /locus_tag="VQO19_000855"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HET1349146.1"
                     /translation="MKELQTVLKNHFAIEFTDKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            14784..18323
                     /gene="smc"
                     /locus_tag="VQO19_000856"
     CDS             14784..18323
                     /gene="smc"
                     /locus_tag="VQO19_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HET1349147.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRSI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDENAATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLGSEEVALKTLQDEMARLIESLEAIKSQGEQARIQEQGLFLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKENCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTDLLNQQAEEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDQYEEVRNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            18320..19114
                     /locus_tag="VQO19_000857"
     CDS             18320..19114
                     /locus_tag="VQO19_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET1349148.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEVTMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEDGEAWVNENVPGVKAMTTGFESIDIVLDYVDKGVAIVELVKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            19114..19932
                     /locus_tag="VQO19_000858"
     CDS             19114..19932
                     /locus_tag="VQO19_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET1349149.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSNQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            19936..21213
                     /gene="ftsY"
                     /locus_tag="VQO19_000859"
     CDS             19936..21213
                     /gene="ftsY"
                     /locus_tag="VQO19_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HET1349150.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVIEVSQKEVKEFPHSEEGNTEFLETVE
                     ENNSEVLEAERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(21259..22746)
                     /locus_tag="VQO19_000860"
     CDS             complement(21259..22746)
                     /locus_tag="VQO19_000860"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HET1349151.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRLE"
     gene            complement(22895..23635)
                     /locus_tag="VQO19_000861"
     CDS             complement(22895..23635)
                     /locus_tag="VQO19_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET1349152.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(23635..25800)
                     /locus_tag="VQO19_000862"
     CDS             complement(23635..25800)
                     /locus_tag="VQO19_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET1349153.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSTIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPIAGTPIGETA
                     FAVKKGTNPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            25970..26924
                     /locus_tag="VQO19_000863"
                     /pseudo
     CDS             25970..26924
                     /locus_tag="VQO19_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            27001..28989
                     /gene="uvrB"
                     /locus_tag="VQO19_000864"
     CDS             27001..28989
                     /gene="uvrB"
                     /locus_tag="VQO19_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HET1349154.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDITSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            28999..29562
                     /locus_tag="VQO19_000865"
     CDS             28999..29562
                     /locus_tag="VQO19_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET1349155.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            29528..30037
                     /locus_tag="VQO19_000866"
     CDS             29528..30037
                     /locus_tag="VQO19_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET1349156.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRLFSQKYPENTLIAIGDLKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALDHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SKIILKSRS"
     gene            30090..30557
                     /locus_tag="VQO19_000867"
     CDS             30090..30557
                     /locus_tag="VQO19_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET1349157.1"
                     /translation="MSRSQLTILTTICLIEDLETQRVVMQYRAPETNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVVCYKATEFSGTLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMESPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(30554..31069)
                     /locus_tag="VQO19_000868"
     CDS             complement(30554..31069)
                     /locus_tag="VQO19_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HET1349158.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(31081..31608)
                     /locus_tag="VQO19_000869"
     CDS             complement(31081..31608)
                     /locus_tag="VQO19_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET1349159.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(31890..32453)
                     /locus_tag="VQO19_000870"
     CDS             complement(31890..32453)
                     /locus_tag="VQO19_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET1349160.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILSLAIVPRLQTLKK"
     gene            complement(32437..32988)
                     /gene="coaC"
                     /locus_tag="VQO19_000871"
     CDS             complement(32437..32988)
                     /gene="coaC"
                     /locus_tag="VQO19_000871"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HET1349161.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLSLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(33000..33689)
                     /gene="coaB"
                     /locus_tag="VQO19_000872"
     CDS             complement(33000..33689)
                     /gene="coaB"
                     /locus_tag="VQO19_000872"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HET1349162.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPESHPNLSIREITNTKDLLIEMQERVQDYQILIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            33919..35589
                     /locus_tag="VQO19_000873"
     CDS             33919..35589
                     /locus_tag="VQO19_000873"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HET1349163.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKLR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
BASE COUNT        10984 a         6331 c         7937 g        10419 t
ORIGIN      
        1 ttagtgtaat tgagaaagga gaaatgattg tgattgatgt tggctaggtt atgttcaatg
       61 attcctaccg tctcaaatct tgtcagtaag gaaaaataaa ttcttcaaaa gtagagatta
      121 caaggcttgt ttaagaaaga attcaaagac cttgacaaat aaaaataaaa tggttattat
      181 aagaaatggt ctaaaataga tgatgatact tttcgaaaat ctttttacgt cagctcagct
      241 ttgccttgct gtgttttgag caagctacgg ttagcttccg agtttgattt tcatttacta
      301 gaaatgaaac tgatgagaga tatcagtaga catttgagtc aggatattat ggaaaatgat
      361 aaaaagagct tgtgagattg gcatatcaga ctactaaagt attgagtttg ttaggatttt
      421 agcgactagt tagctgggaa aggaagatat ttgtgacaaa taataaactg tattcgttga
      481 tagaatttag aaataaaata tatgaagaat tagaactttc cagaagtgat ttagcgattt
      541 tactatgtgc catgcttatc gcctctatcg gattaaatat ggattcgact cccgtgatta
      601 ttggagccat gttaatctct cctttgatga cacctattct gggagtgggg ctctctctag
      661 ctatatttga ttttaaattg ttaagaaaat cttttaaaat attagctatt caaattcttg
      721 ccagtctaat agcttcaaca ctttattttt atctttctcc catttcgtat gctagttcgg
      781 agattgttgc tagaacctct ccgactattt gggatgttct cattgctttt gtaggaggga
      841 tagcaggtat tattggtgct aggaaaaaag agaccaataa tattgttcct ggtgttgcta
      901 ttgcaaccgc cttgatgcct cctctttgta cagtaggtta tgctattgct tctgctaatc
      961 taaaatttat cataggctcc tcttacctat tcctcatcaa ttgtagcttt attgtcattg
     1021 cgacttatat aggtgttagg ttgatgatgg ttaagaaaca ttattttaaa gataatgaag
     1081 aagactctaa aatgcgtagg attttgcttc tagttgctgt tttgctgatg attccgagtt
     1141 tcatctctgc aacgacttta gtgagagaaa cgttgaaaaa agagtccctt aagaaattta
     1201 tatcagagca gtttcagggg tataatattt tgaaaaaaac ctattctaaa aagactcata
     1261 ccctaaagct aaccatttca ggaaattatt tgacagaaga agaactcgat atgatttcaa
     1321 gtaagagagg tgactatggt ttaagtgatg tttctgttca agtttcacaa ttgtctgatt
     1381 cagaacaact tagtaaggaa gagctggtgg agtatttctt ccagtatatc aaggataagg
     1441 aagcaaaaga aaaggaaaaa gctaataagt tttatacaga gtctgaggag caataatttc
     1501 ttgagaatag ctggtttttc tcgtgagtct tctatgtata tcaaaggaag actgaggttt
     1561 taagtataaa acttttcttc tattatagta gctaagtctt gacagggttc aaaaaatggt
     1621 ttacacttta taaagtttat tactttgaaa aggtgtgata ctgtggctac ggcaacaaaa
     1681 aagaaaaaat caacagttaa aaaaaatcta gtcatcgtgg agtcgcctgc taaggccaag
     1741 acgattgaaa aatatctagg cagaaactac aaggttttag ccagtgtcgg gcatatccgt
     1801 gatttgaaga aatccagtat gtccgtcgat attgaaaata attatgaacc gcaatatatt
     1861 aatatccgag gaaaaggccc tcttatcaat gacttgaaaa aagaagctaa aaaagctaat
     1921 aaagtttttc tcgcgagtga cccggaccgt gaaggagaag cgatttcttg gcatttggcc
     1981 catattctca acttggatga aaatgatgcc aaccgtgtgg tcttcaatga aatcaccaag
     2041 gatgcagtca aaaatgcttt taaagaacct cgtaagatcg atatggactt ggtcgatgcc
     2101 caacaagctc gtcggatctt ggaccgcttg gtagggtatt cgatttcgcc tattttgtgg
     2161 aagaaggtca agaagggctt gtcagcaggt cgcgttcagt ccattgccct taaactcatc
     2221 attgaccgtg aaaatgaaat caatgccttc cagccagaag aatactggac agttgatgct
     2281 gtctttaaaa agggaaccaa acaatttcat gcttccttct atggagtaga tggtaaaaag
     2341 atgaaactga ccagcaatga cgaagtcaag gaagtcttgt ctcgtctgac gagtaaagac
     2401 ttttcagtag atcaggtgga taagaaagag cgcaagcgca atgctccttt accctatacc
     2461 acttcatcta tgcagatgga tgctgccaat aaaatcaatt tccgtactcg aaaaaccatg
     2521 atggttgccc aacagctcta tgaaggaatt aatatcggtt ctggtgttca aggtttgatt
     2581 acctatatgc gtaccgattc gactcgtatc agtcctgtag cgcaaaatga ggtggcaagc
     2641 ttcattacgg atcgttttgg tagtaagtat tctaagcacg gtagcaaggt caaaaacgca
     2701 tcaggtgctc aggatgccca tgaggctatt cgtccgtcaa gtgtctttaa tacaccagaa
     2761 agcatcgcta agtatctgga caaggatcag ctcaagctat atacccttat ctggaatcgt
     2821 tttgtggcta gccagatgac agcggccgtt tttgatacca tggctgttaa attgtctcaa
     2881 aaaggggttc aatttgctgc caatggtagt caggttaagt ttgatggtta tcttgccatt
     2941 tataatgatt ctgacaagaa taagatgtta ccggacatgg ttgttggaga tgtggtcaaa
     3001 caggtcaata gcaaaccaga gcaacatttc acccaaccgc ctgcccgtta ttctgaagca
     3061 acactgatta aaaccttaga ggaaaatggg gttggacgtc catcaaccta cgcgccaacc
     3121 attgaaacca ttcagaaacg ttattatgtt cgcctggcag ccaaacgttt tgaaccgaca
     3181 gagttgggag aaattgtcaa taagctcatc gttgaatatt tcccagatat cgtaaacgtg
     3241 accttcacag ctgaaatgga aggtaaactg gatgatgtcg aagttggaaa agagcagtgg
     3301 cgacgggtca ttgatgcctt ttacaaacca ttctctaaag aagttgccaa ggctgaagaa
     3361 gaaatggaaa aaatccagat taaggatgaa ccagctggat ttgactgtga agtgtgtggc
     3421 agtccaatgg tcattaaact tggtcgtttt ggtaaattct acgcttgtag caatttccca
     3481 gattgccgtc atacccaagc aatcgtgaaa gagattggtg ttgagtgtcc aagctgtcat
     3541 cagggacaaa ttattgagcg aaaaaccaag cgtaatcgcc tcttctatgg ttgcaatcgc
     3601 tatccagaat gtgaatttac ctcttgggac aagcctgttg gtcgtgactg tccaaaatgt
     3661 ggcaacttcc tcatggagaa aaaagtccgt ggtggtggca agcaggttgt ttgtagcaaa
     3721 ggcgactacg aggaagaaaa gattaaataa gaggaggggc ccgaaagtaa atttcaggct
     3781 ccttttggtt agaacttgac aaaatacatc attttatgcg aaactagaag aagattattt
     3841 taactaggag aagttatgcg tcttatctat ctgataattg gttttttatc actgaccttg
     3901 gctattgttg gggttgtttt acccttgttg ccgacaacgc ctttcctttt gttgtctatt
     3961 gcttgtttct ccagaagttc caagcgtttc gaagactggc tttatcatac caagctctat
     4021 caaacatatg tagctgattt tcgcgagact aagtctatta cgcgtgaacg aaagaaaaaa
     4081 atcatcgtat ccatttacat tttgatgggg atttctattt attttgcccc tctcttacca
     4141 gtcaaaatcg gtctgggtgc tttgaccatc tttatcactt attatctttt caaggtcatt
     4201 ccagacaaag aatagttaaa acagtagtta tttgccttga taaaattgaa agcatattca
     4261 taacaatatg atataataaa tttgaagtaa tattcaagga gaatcaaatg atttacgaat
     4321 tttgtgctga aaatgtgact ttacttgaaa aagcgatgca ggctggagct cgtcggattg
     4381 aactctgtga taatctagca gttggtggga caacacccag ctatggagtg actaaggcag
     4441 cggttgaact ggcagctaac tacgatacaa ccatcatgac catgattcgg ccacgtggtg
     4501 gtgactttgt ctataatgac ctagaaattg ctatcatgct agaagacatt cgtttgactg
     4561 ctcaggctgg aagtcaaggg gttgtatttg gaactttaac tgctgataaa aagttggata
     4621 agcctaatct ggaaaagtta attgctgcat caaaaggaat ggaaattgtc tttcacatgg
     4681 cctttgatga actaagtgat gaagatcaac tggaagctat tgactggctc agtcaagccg
     4741 gtgtcactcg tatcctaact cgtgctggtg tgtctggcga ctccttagaa aaacgttttg
     4801 ttcactatca cagaattttg gagtacgcta aaggtaaaat tgaaattcta ccaggtgggg
     4861 ggattgacct tgaaaaccgt caaaccttta tcgaccaggt gggggtaaca caattgcatg
     4921 gtactaaggt tgttttttaa aaaatagaaa ggaactgcta gctttgggta gcagttttca
     4981 cttatgtttg aaatttttaa atcctatcaa tttaatcaag aaaaggctca tgattatggt
     5041 tttatagaaa atagcgaagt ctggacatat agttgccaga ttttgcaagg tgactttgtc
     5101 atgactgtgt ccatcactgc tgataatgtg aactttcaag tctttgacca agagactggt
     5161 gacctctatc ctcaagttca tatggaaagt atgacaggaa gttttgttgc aagtgtccgt
     5221 gaggcttgtc tggagattct ttaccagatt cggaaggctt gttttgatgt gcaagatttt
     5281 atctgtcatc agactaagcg tatcatgact caagttcagg aaaagtatgg aaaccagttg
     5341 gagtatctgt gggaaaaatc gcctgataca gctgtattgc gccatgaagg caatcaaaag
     5401 tggtatgccg tcttgatgaa aatctcttgg aataagctgg aaaagggcag agaaggacaa
     5461 gtggaagcag tcaacctcaa gcatgaccaa gtagctaatt tgctttcaca aaaggggatt
     5521 tatccagcct tccatatgag caagcgctac tggattagtg tgtcccttga tgatacttta
     5581 tcagatgaag aagtactgga attgatagaa aaaagttgga acttaacctc taaaaaatga
     5641 aatattttaa taattttcat gaactttcaa ttagctaaat attctttact gaagaaattt
     5701 tcagaaaata tagaatttac cgcgccagag gaatatggtg ccatcttcaa atacctgatt
     5761 gagaatgtca agacggatcg tcagatcatc tattcgcctc actgtcatga tgacctcgga
     5821 atggcagtgg caaatagtct tgctgctgtc aagaatggtg caggacgtgt tgaagggact
     5881 atcaatggta ttagggagcg agctggaaat gctgctttgg aagaaattgc agtggctctc
     5941 aatattcgcc aagattacta ccaagtagaa accagtattg tcctaaatga gaccatcaat
     6001 acgtcagaaa tggtttctcg cttctctggt attccagttc ctaaaaacaa agccgtcgtt
     6061 ggtggcaata ccttctccca cgaatctggt attcaccaag atggagtcct taaaaatcct
     6121 ctcacttatg agatcatcac acctgaattg gttggtgtta agattccgct tggaaaatta
     6181 tctggtcgcc atgcttttgt tgagaaactg agagaattgg ccctagattt tacagaagag
     6241 gatatcaaac cactctttgc taagttcaag gcactggtct ataagaagca agaaatcaca
     6301 gatgcagata ttcgagcttt ggtagctgga accatggttg aaaatccaga aggcttccac
     6361 tttgatgatt tacaacttca aactcatgca gataatgaca ttgaagcgct cgttagccta
     6421 gccaatatgg atggtgagaa agtcgaattt aatgcgacag ggcaaggttc cgttgaagca
     6481 atctttaatg ctatcgataa gttctttaac caatctgttc gtttggtgtc ctacactatc
     6541 gatgcggtaa cagatggaat cgatacccag gatcgggttt tggtcactgt tgaaaacaga
     6601 gatacagaaa ccatctttaa tgcagcaggg cttgattttg atgtgttgaa ggcttctgct
     6661 attgtctata taaacgctaa tacctttgtt caaaaagaga atgcaggtga gatgggacgc
     6721 agtgtttctt accacgatat gcctagtgtg taaaggagaa ggctatggca aagaaaatag
     6781 tagctctagc aggagacgga attggcccag aaatcatgga ggttggttta gaagttctgg
     6841 aggctctagc tgaaaaaaca ggttttgact atgagattga cagacgaccg ttcggaggtg
     6901 cagatattga tgcagcatgg cctcccttac ctgatgaaac ccttaaggca agtagggaag
     6961 cagatgctat cctactagca gctatcggta gtcctcagta tgatggagca gtggttcgcc
     7021 ctgaacaagg cctgatggct ctccgtaagg aactcaatat ttacgctaat attcgtcctg
     7081 taaaaatctt tgacagtctc aagcatttgt caccactcaa actggaacga attgctggtg
     7141 tagactttgt cgtggtgcgt gaattgacag gcgggattta ctttggagat catattcttg
     7201 aagagcgcaa tgcgcgtgat atcaacgact atagctatga ggaagtggag cggattattc
     7261 gcaaagcctt tgaaattgca agaaatcgca gaaaaatcgt tactagtatc gataagcaaa
     7321 atgttctagc gacctcaaaa ctctggcgga aggtagctga ggaagtcgca caggatttcc
     7381 cagatgtaac cttggaacat cagctggtag actcagctgc tatgcttatg attaccaatc
     7441 ctgctaagtt tgatgttatt gtaacggaga atctttttgg agatatttta tctgatgaat
     7501 caagcgtctt atctggtaca cttggggtta tgccatcagc cagtcattct gaaaatggac
     7561 caagtctcta tgaacctatt cacggttcag cacctgatat tgcaggtcaa ggaattgcca
     7621 atcctatttc catgatttta tcagttgtca tgatgttgag agatagtttc ggacgttatg
     7681 aggatgcaga gcgtatcaaa cgtgctgttg agacaagtct ggcggcagga attttaacga
     7741 gagatatagg aggtcaggct tcaacaaagg aaatgacgga agctattatt gcaaggttat
     7801 gaagttagac gaaaaaatta ctctagtcct tttgatttgg aatgtcatca ttttcttgat
     7861 ttatggcatt gacaaattca aggcaagaag aagagcttgg cgcatccaag agaaaatctt
     7921 actcatttta gcccttactt gtggtggttt tggggcctgg ttagctggaa tcacttttca
     7981 ccacaagact cgaaaatggt actttaaaac agtttggttt cttgggatgg tgactacact
     8041 agtagcctta tattttattt ggaggtaatg gatggcaggg tcttcgaggg aacacgctgc
     8101 ttgggctcta gcgaactatg gttttaaggt cgtgattgca ggaactttcg gtgacattca
     8161 ttacaataat gaactcaata atggcatgtt gccaatcgtt cagcctagag aggttagaga
     8221 gaaactagcc cagctaaaac caaccgacca tgtaactgtg gacttggaac aacaaaaaat
     8281 catctcacca gttgaagaat tcaccttcga gatagatagc gagtggaaac ataaactcct
     8341 aaatagtttg gatgatatcg gtattacctt gcagtatgaa gagttgattg ctgcttatga
     8401 aaaacaacga ccagcctact ggcaggatta gaaaaaatag aaaaggaaat atagtaaact
     8461 gaaataagat gtaaacaaat gaattagagc ttaacatcca tttccagcaa ttttttagaa
     8521 actacagtgg actattctgg attcaacaca ttataaaatt atgacaaaac acattcacaa
     8581 gaaggctacg acattttaaa aggtgagggt ggatgtatcg tttgccctac taaagttggt
     8641 tacattatca tgaccagtga taaggcagga cttgagcgta agttcgcagc caaagaacgt
     8701 aagcgtaaca aaccaggtgt tgttctctgc ggtagcatgg atgaactttg cgctttagcg
     8761 caactcaacc cagaaattga agcattctac taaaaacatt gggatgaaga tattcttctt
     8821 ggttgtatcc ttccttggaa accagaagcc tttgaaaaac tcaaagcata cggggatggc
     8881 cgtgaagaac ttatgactga tgtacgtggt actagctgtt ttgttatcaa gtttggaaaa
     8941 gcaggtgaac aattggctgc caagctttgg gaagaaggta aaatggtcta cgcctcatat
     9001 gcttcaatga caaaacgatt gaaactcgct atgagagcaa ggtgtaatgg tgtctatggt
     9061 cgataaggac ggcaaactca tcccagaaca aggaggagca cgttcaacct caccagcacc
     9121 agttgtgatc cgtaaagggc ttgacattga taaaatcatg atgcacctgt cagacacctt
     9181 taactcatgg gattaccgtc agagagagta ttattaggat aaaaaagaag tctagtgtta
     9241 tgagatatta aagctcctaa cactgggctt tttgtttaga atttcttttc tttttctata
     9301 ggatatggta ttctatgtag aaaatatatg ttaataagta atgccaatat ttaaacatca
     9361 ttagtaaaag gagttagatt gatgaataaa agaaaagtta gtttagaaga tttttataaa
     9421 tggtatagtc taaataaaga agagttatta aataaggcaa ctgttggtga aaagtttaat
     9481 gataaattaa aagaagagtt tctccaggaa tggcctttgg ataggatttt aacaatgtca
     9541 atcgatgaat atgtaatagg aaagggacag caaaataagt ctttatgcta cgctcttgag
     9601 aagggaaaat acaaaaatct atttcttgga atttctggtg gctcagcttc aaaatttggt
     9661 atttattgga ataaaaaaac aaacaaatat aaagatcaag ctaataatga gatttcagag
     9721 ttggatcagc gattttcaaa attaaaatca gatttgtatg aaattatcaa agaaggtatt
     9781 cgttttaact ttgaaaatcc tatttttgat atgaaaagat caacaaatga atttattggt
     9841 cgttctgcta tggtgacaaa attactttgt atctatactg agggagatcc tttctttggt
     9901 gtaaatatta atagtcagaa agaattttgg aaccactttg tttctcagac aaatcaaggt
     9961 ggaccttatc tgcaaaatca taaaataatt gaactggtgt ccaaaactta tcctgagttg
    10021 gagccatcga aattaggaac tatgcttttt gagtattcta agctttttat ggaaaataag
    10081 gaagacaata gtacaatgga ttcatcaaac aattttagtc atcaattaac tcaatctcta
    10141 ttaaagtctc caaaccttat ccttcgtggt gctcctggca caggaaagac ttatcttgct
    10201 aaagaaattg ccaaagaatt aacggatggc aacgaagacc aaatcggatt tgtacaattt
    10261 cacccatcct atgattatac ggattttgta gaaggtttaa gaccagtatc aaatggggat
    10321 ggagctattg agtttaggct acaggacggt atttttaaag atttttgtca gaaagcaaaa
    10381 gaaccccaat tgattggagg acaagataat tttgatgagg cttgggattc ttacttagaa
    10441 tatataaatg ttgctgaaga aaaagaatat ataacaaaaa catcttactt atctgttaat
    10501 agtagacaaa atttgtcagt aaattatgat agtggtgttc caggatggtc actacctagc
    10561 aaatatgttt acgagttgta taaagataaa aattataata agcaagaata ctacaaaagt
    10621 ggtggaaaaa ctgtcctaga aacattgaga aagagatttg gtttgaaaga ctatgtttcc
    10681 ccaacagaaa ttgatactga taagaaattc gtcttcatca tcgatgaaat caatcgtggg
    10741 gagatttcta agatttttgg cgaactcttt ttctctatcg accctggcta tcgtggtgaa
    10801 aaaggaagtg tttctaccca atatgcaaat ctacacgaaa ctgatgaaaa gttctatatc
    10861 cccgaaaatg tttacatcat cggaactatg aatgatattg atcgttcagt ggataccttt
    10921 gattttgcta tgcgtcgtcg ttttcgtttt gttgaagtta ctgccgaggg tcaagttggc
    10981 atgttggata aagagttgaa tatccatgca gaagaagcaa aaattcgtct aagaaacttg
    11041 aacgctgcta tcgaaaatgt tcaggaatta aacagtcatt atcatattgg accaagttat
    11101 tttcttaagt tgaaggatgt agattttgac tatgaattac tctggtctga ttatattaag
    11161 cctctcctag aagactactt gcgaggttct tatgatgagg ttgaaacttt ggaaactttg
    11221 aaaaaagcat ttgatctgac aaataatgag caaaaagatc aggcagtagc tgatgacaat
    11281 gaaggcgatg aaaacgatga tgcggattac tgataatcaa cacaagatta ttaaagaaaa
    11341 atttgttgaa gaatatccta aactaagcaa tcctctttta gacagaacct tggaaagtct
    11401 atcccaagat gaacgtattt tcatttttcc aaatgatttg actcatactc ctgatttgga
    11461 taaggaccaa aagatttttg aaacagtcaa tcagaaaatt aagacaggga acgtgattgg
    11521 ttttcttgga tatggtcagg aaagattaac gatttcctca cgattttctg atgagagtaa
    11581 tgaccatttt ttgcattatc tcttaaacaa ggttcttcat atcaatctca ctagtttaga
    11641 tgttgctttg tctcgtgaag agaggcttta tcaacttttg atgtatctct tccccaagta
    11701 tctacaagct gctattcgaa aaggtcttta taaggaatat catcgatttt ctcataacga
    11761 cagtcatgtt aagggagtga ttgatgtaag aagccatctc aagaaaaatc ttcctttcac
    11821 gggaaatatt gcctacacaa cgagagagtt cacctatgat aatcccctca tgcagttggt
    11881 ccgtcacact attgaataca ttgagaatca gaaaagcatt ggtcaagggg tactagataa
    11941 tctctcaact agtcgtgaaa acgtatctga aatcgtgcgt gtaacgccct cttataaact
    12001 agctgatcgt gctaagatta ttcggggaaa tcaatctaaa cctatacgtc atgcatactt
    12061 tcacgagtac agaaacttac aagaactttg tctgatgatc ctaaaccaag aaaagcacgg
    12121 tttagggtat caagatcaaa aaatctatgg tattctcttt gatgttgcct ggctttggga
    12181 agagtatgtt tacaccttgt tgccaaaagg ttttgtacat cccagaaata aggataagac
    12241 ggatggaatt tcagtatttt ctgttgggaa acgaaaagta tatccagatt tttatgacag
    12301 agaacgaaag attgttctag atgcaaaata taaaaaactg gaattgactg aaaaaggaat
    12361 caaccgtgag gacttattcc agctgatttc ctattcttat attttaaaag ctgagaaggc
    12421 tggactgatt tttcctagta tggagcagtc agtaaatagt gaaataggaa aagtagctgg
    12481 ctatggagct caattgaaga agtggtctat tcgaatccct cagaatgcct catcctatag
    12541 tgcattttgt aaaatgatgg aaaattcaga agaaaatttt aaagcgatta ttgatgaaga
    12601 agtggggaga aaataatttc ccctctttct tttattttta acacaagcaa aacccgaacg
    12661 atatatttta attcataaaa taatttgaca aaaactgtac tttggtttat aataaattaa
    12721 ggaaacgtcg gaaaaggcgt agtgatgcga gagcataggt aggtcattac aaaagaaacg
    12781 agacatcgat atgttaaatg aatttccaat ttttgattac gaagatattc aattgattcc
    12841 aaataaatgt gtcattaaaa gccgtgcaga agcggataca agtgtcactt taggaaatca
    12901 cacctttaaa ctacctgttg tgccagcgaa tatgcagacg attttggatg aaaatgtagc
    12961 agagcaactg gctaaaggtg gttacttcta cattatgcac cgttttgatg aggcaggacg
    13021 cattcctttt attaaacgaa tgcacgatca agggctcatt gcttccatat ctgtcggtgt
    13081 taaggactat gagtatgatt tcgttagaca gctcaagact gatgctcctg agtatatcac
    13141 tattgatatt gctcatggtc atgcggatag cgtgatttct atgattcaac acatcaagaa
    13201 agaattgcca gatacctttg taattgctgg aaatgtggga acaccagaag ctgtgcgtga
    13261 attggaaaat gctggtgcgg atgctactaa ggtcggaatc ggtcctggta aggtttgtat
    13321 caccaaggtt aagactggtt ttggtacagg tggttggcag ttggctgctc tacgctggtg
    13381 tgccaaggct gcgcgtaaac cgattatcgc tgatggagga attcgtactc acggtgatat
    13441 tgccaagtct atccgcttcg gtgctagcat ggtcatgatt ggttccctct ttgcaggaca
    13501 cattgaaagt ccagggaaaa cgattgaagt cgatggtgaa cagttcaaag aatattatgg
    13561 ttcagcctca caatatcaaa aaggtgctta caaaaatgtg gaaggcaaac gtatcttgct
    13621 tcctgctaaa ggtcatctgc aagacacttt aactgagatg gaacaagacc ttcaaagtgc
    13681 tatttcttat gcaggtggac gtcaggttgc tgaccttaaa cacgttgatt atgtgatcgt
    13741 gaaaaactcc atctggaatg gggatgcttc ccactaagac ggggtctttg accaaaaaac
    13801 ttgttattag agcaaatttc tgttataata aaacaagttt ccacccttag tgtaatggat
    13861 atcacgtaag attccggttc ttgagatggg ggttcgattc cctcagggtg gatgtaaaca
    13921 tcctaaaaag cctttaatag ggcttttttc tttatcctga cccaaatttg ccgctaaaac
    13981 tgagaatctc tgtctaaaga attcccaaat gctttccagt cccgttttag agtgactcag
    14041 ggggcttttt ttgatataat aaaaaggact attatcagtt agaaagaggt tggtatgaaa
    14101 gaattacaaa ctgtactaaa gaaccatttt gcaatcgaat ttacagacaa aaagttactg
    14161 gaaactgcct ttactcatac gagttatgcc aatgagcacc gcctcttaaa aatttcacat
    14221 aatgaacgct tggaattttt aggagacgct gttctacagt tattgatttc agaatatctg
    14281 tataaaaaat atcctaaaaa gcctgaaggt gacctatcaa aactccgtgc tatgattgtc
    14341 cgtgaggaga gtttagctgg ttttgcgcgt gattgccagt ttgaccagtt tatcaagttg
    14401 ggtaaagggg aagaaaaatc tggtggtcgc aatcgtgaca ccattcttgg tgatgccttt
    14461 gaagcctttc ttggtgccct tcttttggat aaggatgtgg ccaaggtcaa ggaatttatc
    14521 tatcaagtca tgattcctaa ggttgaagca ggcgaatttg agatgattac agactataaa
    14581 acccatctcc aagagttgct tcaggtcaat ggtgatgtgg ctattcgtta tcaggtgatt
    14641 tctgaaacag ggcctgctca cgataaggtc tttgatgtag aagttcttgt tgaaggtaag
    14701 agcatcggtc aaggccaagg tcgttctaag aaattagcag agcaggaagc tgccaaaaat
    14761 gccgttgaga aggggctgga ttcatgtatt taaaggaaat cgaaattcag gggttcaagt
    14821 cttttgctga taagaccaag gtcgtttttg accaaggtgt gacggcagtt gttggaccca
    14881 atggatctgg aaagtccaat attacagaaa gtctgcgttg ggctttgggg gagtctagtg
    14941 tcaagagtct ccgtgggggc aagatgccgg atgtcatctt tgctggaacc gaaagtcgca
    15001 aaccgctcaa ttatgcttct gtagttgtga ctctggataa tcatgacgga tttatcaagg
    15061 atgcaggtca agaaatcagg gtggaacgcc atatctatcg tagtggagat agcgaataca
    15121 agattgacgg caagaaagtt cgtcttcgtg atattcatga tctcttcttg gacacaggtt
    15181 tgggacgaga ttccttttcc atcatttccc aagggaaggt tgaggagatt tttaattcca
    15241 agcctgagga acgacgatct atttttgaag aagctgctgg agttttaaaa tacaagactc
    15301 gcagaaaaga aaccgagagt aaactgcagc aaactcagga taatctggac cgcttagagg
    15361 acattatcta cgagttggat aatcaaatca agcctcttga gaagcaagct gagaatgccc
    15421 gtaagttttt agacttggaa ggacaacgta aggctattta tttagacgtt ctggttgctc
    15481 aaatcaagga aaataaggct gaactagagt cgacagaaga agagttggct caggttcaag
    15541 aactcttgat gagttattac caaaagcgtg aaaaattaga agaagaaaat caaactctta
    15601 aaaagcaacg ccaagattta caggctgaaa tggccaaaga ccaaggcagt ttgatggact
    15661 tgactagtct gattagtgat ttagaaagaa aattagccct atcaaaactg gagtccgagc
    15721 aagtggcctt gaatcaacag gaggcacaag ctcgtttggc tgctttggag gataagagaa
    15781 attcactcag caaagaaaag tctgataaag aaagctcttt agctctgtta gagggaaatc
    15841 tagtccaaaa taatcaaaaa ctcaatcgtt tagaagctga attgctggct ttctcagacg
    15901 atcctgatca gatgattgag ctcttacgtg aacgctttgt agctctttta caagaagaag
    15961 cggatgtctc aaaccagttg acccgtattg agaatgagtt ggaaaatagt cgtcagcttt
    16021 ctcaaaaaca agcagatcaa ctagaaaagc tgaaagagca attggctata gctaaagaga
    16081 aggctagtca gcaaaaggaa gagcttgaaa ctgccaagga gcaggttcag aaattattgg
    16141 ctgactacca agctattgcc aaggagcaag aggagcagaa aacttcctat caagctcaac
    16201 aaagccaact ctttgaccgt ctggataatc tcaaaaacaa gcaggccaga gctcaaagtt
    16261 tggaaaatat cctgagaaat catagtaact tttatgcagg tgttaagagt gttctccaag
    16321 aaaaagatcg cctaggtggg attattggtg cagtcagtga gcatctgacc tttgatatgc
    16381 attatcaaac tgccctagaa attgcacttg gagcgagtag tcagcacatt attgtagaag
    16441 atgagaatgc ggcaaccaaa gccattgatt tcctcaaacg aaacagagcc ggtcgtgcaa
    16501 cctttcttcc tttgaccact attaaggcgc gtacgatttc tagtcagaac caagatgcta
    16561 tcgctgtaag cccaggtttc cttgggatgg cagatgagtt agttactttc gatactagac
    16621 tggaagccat tttcaagaac ttgctagcta cgacggctat ctttgatacc gtagaacatg
    16681 cgcgtgaagc tgctcgacaa gttcgttatc aggttcgcat ggtgacattg gatgggacag
    16741 agcttcgtac aggtggttcc tatgcaggtg gagccaatcg tcagaacaac agtatcttca
    16801 tcaagccaga actggagcaa ttacaaaaag aaattgctga agaagaagca agcttgggtt
    16861 cagaagaagt ggctttgaag accttgcaag atgagatggc cagattgatc gagtcattag
    16921 aagctattaa atctcaagga gagcaggcac gtattcagga gcaaggcttg ttcctcgctt
    16981 atcagcaaac tagtcagcaa gttgaagagc tagaaactct ttggaaactc caagaagagg
    17041 aaatagatcg tctttccgag ggagattggc aagcggataa ggaaaactgc caagagcgtc
    17101 ttgctgcaat cgccagtgac aagcaaaatc tggaagctga gattgaagag attaagtcta
    17161 acaaaaatgc catccaagaa cgctatcaaa acttgcagga agagctagcg caagctcgtt
    17221 tgcttaagac agaactgcaa gggcaaaaac gttatgaagt tgctgatatt gagcgtttag
    17281 gcaaggaatt ggataatctt aatatcgaac aagaagaaat ccagcgcatg ctccaagaaa
    17341 aagttgacaa tcttgagaaa gttgatacgg atttgctcaa tcagcaggcc gaagaagcca
    17401 aaactcagaa aacaaatctc caacaaggtt tgattcgcaa gcagtttgag ttggatgata
    17461 tagaagggca gctggatgat attgctagtc atttggatca ggctcgccag cagaatgagg
    17521 agtggattcg caagcaaaca cgtgctgaag ccaagaaaga aaaggtcagc gagcgcttgc
    17581 gccatctaca aagtcaatta acagaccagt accagattag ctatactgaa gctctagaaa
    17641 aagcgcatga attggaaaac ctcaatctgg cagagcaaga agttaaggat ttagagaagg
    17701 ctattcgctc actgggccct gtcaatatag aagctattga ccagtacgaa gaagttcgca
    17761 accgtctgga ctttctaaat agtcagcgag atgatatttt gtcagcgaaa aatctgctcc
    17821 ttgaaaccat tacagagatg aatgatgagg tcaaggaacg ctttaaatca acctttgaag
    17881 ctattcgtga gtcctttaaa gtgaccttca agcagatgtt tggcggaggt caggcagact
    17941 tgatattgac tgagggcgac cttttaacag ctggtgtgga gatttctgtt caacctccag
    18001 gtaagaaaat ccagtcgctt aacctcatga gtggtggtga aaaagctcta tcggctcttg
    18061 ccttgctttt ctccattatt cgtgtcaaga ccattccttt tgtcatcttg gatgaggtgg
    18121 aagctgcgct ggatgaagcc aatgttaaac gttttgggga ttacctcaac cgctttgaca
    18181 aggacagcca gtttatcgtc gtaacccacc gtaagggaac catggcagcg gctgattcca
    18241 tctatggagt gaccatgcaa gaatcgggtg tttcaaagat tgtttcagtt aagttaaaag
    18301 atttagaaag tattgaagga tgacaattaa actagtagca acggatatgg acggaacctt
    18361 cctagatggg aatggacgct ttgatatgga tcgtctcaag tctctcttgg cttcctacaa
    18421 ggaaaaaggg atttactttg cggtggcttc gggtcgggga tttctgtctc tggaaaaatt
    18481 atttgctgat gtacgtgatg acattatttt catcgcggaa aatggcagtt tggtcgaata
    18541 tcaaggtcag gacttgtatg aagtgaccat gtctcgtgac ttttatctgg caacttttga
    18601 aaagctgaaa acttcacctt atgtagatat caataaactg ctcttgacgg gtaagaaggg
    18661 ttcatatgtt ctagatacgg ttgatgagac ctatttgaaa gtgagtcagc actataatga
    18721 aaatatccaa aaagtagcga gtttggaaga tatcacagat gacattttca aatttacaac
    18781 caacttcaca gaagaaacgc tggaagatgg ggaggcttgg gtaaacgaaa acgttcctgg
    18841 tgttaaggcc atgacaactg gctttgagtc cattgatatt gttctggact atgtcgataa
    18901 gggagtggcc attgttgaat tagttaaaaa acttggtatc acaatggatc aggtcatggc
    18961 ttttggagac aatcttaatg acttacatat gatgcaggtt gtgggacatc ctgtagctcc
    19021 tgaaaatgca cgacctgaaa ttttagaatt agcaaagact gtgattggtc accataagga
    19081 ccagtcggtt atagcttata tggagggctt ataatggcag atataaaatt aatcgcattg
    19141 gacttggacg ggaccttgct gactactgat aaaaggctga cggatcgtac caaggaaacc
    19201 ttgaaagctg cgcgtgatcg tggtatcaag gtcgtattga caactggtcg tcccttaaaa
    19261 gccatggact tctttctcca tgagttaggg actgacggcc atgaagatga gtataccatt
    19321 acttttaatg gtggtttggt tcagaaaaat acaggtgaaa tccttgataa gacagtcttt
    19381 tcatatgatg atgtggcacg cttgtatgaa gaaacagaga aattatcact gcctcttgac
    19441 gctatctcag aaggaactgt ttatcaaatt caatcggacc aagaaagtct ttatgccaaa
    19501 ttcaatccag ctttgacttt tgttccagtt gattttgaag acctgtctaa tcaaatgacc
    19561 tacaacaaat gcgtgaccgc ctttgctcaa gaacccttgg atgcagccat tcagaagatt
    19621 tctccagaat tgtttgacca atatgaaatc tttaaatcac gtgaaatgtt gctagaatgg
    19681 tcaccaaaga atgttcataa agcaacaggt ttggcaaaac taattagcca tcttggaatt
    19741 gatcaaagtc aagtgatggc ctgtggtgac gaggccaatg acctctctat gattgaatgg
    19801 gcagggctcg gtgttgccat gcaaaacgct gttcctgaag taaaggcagc cgcaaatgta
    19861 gtgacgccga tgaccaacga tgaggaagct gtcgcctggg ctatcgaaga atatgtgcta
    19921 aaggagaact aagatatggg attgtttgac cgtctattcg gaaaaaaaga agaacctaaa
    19981 atcgaagaag ttgtaaaaga agctctggaa aatcttgatt tgtctgaaga tgttgatcct
    20041 accttcacag aagttgagga agtttctcag gaagaagcag aggttgaaat tgttgaacaa
    20101 gctgtgttcc aagaagagga aatccaagac acagttgaag aaagtctgga tttagagcca
    20161 gttatagaag tttctcaaaa agaagtcaaa gaatttccac actcagaaga agggaatact
    20221 gagtttctag agactgtaga agaaaataat tctgaagttc ttgaagcaga aaggcctcaa
    20281 acagaagaaa ctgttcagga aaaatatgac cgcagtctta agaaaactcg cacaggtttc
    20341 ggtgcccgct tgaatgcctt ctttgctaac ttccgctctg ttgacgaaga atttttcgag
    20401 gaactggaag aactgttgat tatgagtgat gttggtgtcc aagtcgcttc taacttaacg
    20461 gaggaactac gttacgaagc caagcttgaa aatgccaaga aacctgatgc acttcgtcgt
    20521 gtcatcattg agaaattggt tgagctttat gaaaaggatg gtagctacga tgaaagcatc
    20581 cacttccaag ataacttgac agttatgctc tttgttggtg tgaatggtgt tgggaaaaca
    20641 acttctatcg gaaaactagc tcaccgctac aaacgagctg gtaagaaggt catgctggtt
    20701 gcagcagata ccttccgtgc gggtgcagta gctcagctag ctgaatgggg ccgacgagta
    20761 gatgttccag tagtaactgg acctgaaaaa gctgatccag ccagcgtggt ctttgatggt
    20821 atggaacgtg ccgtggctga aggtatcgat attctcatga ttgatactgc tggtcgtctg
    20881 caaaataagg ataaccttat ggctgagttg gaaaagattg gtcgtattat caaacgtgtt
    20941 gtgccagaag caccacatga aaccttcttg gcacttgatg catcaacagg tcaaaatgcc
    21001 ctagtacagg ccaaagaatt ttcgaaaatc acacctttaa cgggaattgt tttgactaag
    21061 attgatggaa ctgctcgagg aggtgtggtt ctagccattc gtgaagaact caatattcct
    21121 gtaaaattga ttggttttgg tgaaaaaatc gatgatattg gagagtttaa ctcagaaaac
    21181 ttcatgaaag gtctcttgga aggtttaatc taatcagaag caaaaatcct gcaaggcata
    21241 aacttgcagg aaattttttt attctaagcg accatcttga cgataggcga tatctggttg
    21301 ccaagtccat ttggcaccga atttttcaag taggtcaaag ctggcttgag gtcccatgct
    21361 tccagcttta tagtcatgaa gtggggcacc attttcggcc cagagctctt caatacggtc
    21421 aatcaacttc catgacgcac caacctcatc ccagtggcta aagttagttg agttgttatt
    21481 taggacatca taaatcaatt tctcgtatgg ttctggagaa gcaccagttg cagtcgcgtc
    21541 tgtacgataa tcaagtgagt taggagccaa gttaaattct tctcctactt gcttcccatt
    21601 taggctaaga gagaagcctt ctgttggttg aatatagatg gtcaaaatat ttggagcaag
    21661 tggttctcca aagatagaat ccatttgttt aaagacgatg ttgacatgag ttcctttttc
    21721 agtcagtcgt ttacctgtac ggaaaaagaa aggaacacca cggaatcgat cgctgtctac
    21781 aaagaaggca ccagatgtaa aggtttcagt tgttgattct ggattcacat ttggttcgct
    21841 acgataagag atgtatttca tgccatcaat cttaccagag cggtattgtc cacggataaa
    21901 gtgttctttg agttcttcat cagttggatg atagaggttt ttaaagacct taatcttttc
    21961 agcacgaatc tcgtcttttg tgaagcttgc tggtttgtcc atggcgagga gcgaaagaag
    22021 ttgtagagtg tggttttgga ccatgtcacg gagggcaccg gattggtcat agtagccacc
    22081 acgttcttct acacccaagc gctccgcaaa ggtaatttga acattgtcga taaaatcctt
    22141 gttccaaacg ttttcaaaaa tcaagtttgc aaagcgaact gcaaagatgc tttggatcat
    22201 ttccttacca agataatggt caatacggaa aatttgttct tcgtcaaatg ttgctaggag
    22261 ttcgtcattc aacttgcttg cagttgcgta atctgtacca aatggttttt caacgatcaa
    22321 gcgctcaaaa cctttgccat cgacaatgtt ttcagatttg aggtgtttgg caatggttcc
    22381 aaagaactga ggtgccatag acaagaagaa gagcttattg tgttcagctt ggtatttttc
    22441 attaagctca gcttgtaatt gacgcaaagc aatataatgt tccgaatcat tgacatcatg
    22501 gctttgatag tagaagtggc tagcaaattc ttgggcttgc tcggtactat ctgccaaatc
    22561 aaggatggac tcgacaacta cagattcaaa atattcctta ctccaaggtc tacgggcagt
    22621 tccaataacg gcaaagtgct tggaaagatt gccggattta tatagtctaa aaagggaagg
    22681 gtagagcttg cgtttagcca ggtctccact cgcaccgaaa attgtaacaa taaccttaga
    22741 tgacatctag ctacctaatt tctattttta ttcctagtct tgctaggtat gaggaaacct
    22801 catttcataa acttaattct aacataattt tccgaaaaat caaaaattcc aatacgaggt
    22861 agaaaaactg caaggaaatc cttacagttt gagtttagac gtttaagacc ttatctaaga
    22921 actctttcag acgagggtgt tgtgggttat caaagatttg gtcaggtgtt ccgtcttcaa
    22981 ggaactcgcc atctgcagta aagataacgc ggttggcaac ctgacgagca aatcccatct
    23041 catgggttac gataatcatg gtcatgcctt gctcagccaa ttccttcata acgttaagta
    23101 cgtctccaac catctcaggg tcaagggcag aagttggttc atcgaagagc atgatgtctg
    23161 gattcattgc taggccacga gcgatggcca cacgttgttt ttgaccacct gataggctat
    23221 ctggattggc attagcttta tctgctagtc caaccttttc aagcaactcc attcccaatt
    23281 cctcagcttc ttccttagtc atcaacttgt gctcaatagg agcaaaggtg atgttgtcca
    23341 atacagacat atgagggaag aggttgaagt gttggaatac catgccgata ttttcacgga
    23401 cgtggtcaac attggttgtt ttttcagtta aatcatagcc gttcacagtg atgtgaccgc
    23461 tagtgacttc ttctaaaaga ttgaggctac ggaggaaagt tgacttacca gaacctgaag
    23521 gaccgatgat acaaacaaca tctccttcat agaacttagt cgtaattcct tttaggactt
    23581 cattttttcc atagtgcttg tgtaaatcat ttacatcaat ttttaatttt gccattaacg
    23641 aatcctcttt tctaagcgtt tcgctagtct agtcaaaagt gtgataatta caagatagaa
    23701 gatagcaagg attgcataca tcttgaaact ttggtagtta cgagcgatga taatcttacc
    23761 agtttggaag agttcaacca aaccgatagc agatacgata gttgtatctt taagagcgat
    23821 aacgaattgg ttgacaaagt ttggcaacat caatttagtt gcttgtggca agataatctt
    23881 acgcatggtt tttccataag agatacccaa gcttcggctg gcttccattt ggccaactgg
    23941 aacggcctga ataccaccac gaacgatttc agcgatataa gcagccgcat tgagtgagag
    24001 ggcaattgtt ccagctacaa agtcgttaat tgggctttgt tggcctgtga tagactcgat
    24061 gaagtttgga attccccaga agatgaaggc tgcaagaatc atcaatggaa taccacgaat
    24121 aacgtcaacg aaaatctcag agatgacgcg aagagatttg tatgggctaa cgctaaacat
    24181 accgaagata attccgatga caatggcaat agcaaatgag ataagagcta gagcaagagt
    24241 gataccaaga ccgctaagga gttgtttgta gttgttttga agcaagcccc agagcgttgt
    24301 ttcgtcaaca gtacttgttg aagcagttga agattcgcta gctaggtatt tgtcaagaat
    24361 cttttggaat tcaccgtttg ctttaaggtt tgcaagtccg ttgttgaaca tttcaatcaa
    24421 ttcaggattt gtgccttttt taacggcaaa ggctgtttca ccgattggag ttccagcgat
    24481 tggtgttttc aatttttgtc cttgactgat agaatatttg aggacaggct catcatccat
    24541 aacggcatca atggcaccag tgtttaaact gtcatacatt gatgaaccat cagcgaaggt
    24601 tttgattttg taaccgtatt tgctttgatt ttctgttagg aaggtttgag aagcagttcc
    24661 gtttttaaca ccgaccgtct tccctttcaa atcctcataa gaagcaatgg tgcttgattc
    24721 tttgacacca aggatggtat tagcagtgta gtaggattct gagaagtcaa aagttgcctt
    24781 acgagcatct gtgacagaca taccagcaat gataccatca gcttgaccag cttgaacagc
    24841 actgatagca gcatcaaaac cagggttggt aatttcaatt tcaaaacctt ggtctttagc
    24901 gattgcctta atcaattcca tatcaatacc agtgtattgg ttgcttgaat tttggaaaac
    24961 aaaaggtgca aaagaagaat cgctggcaat gatatattta gccttaacag gaatagcttt
    25021 taatcctgcg agagtggttg tagttggcac tgctgaagat gatgaagcag tccatttctt
    25081 gataatttta tcaagactac catctttttt catttcagcc aaggcttggt taaattcagt
    25141 aaccaggtgt tcgtatttac ttcctttttt cacaccgaaa gcaaaacttc ctacagcttc
    25201 accatccatt tcaatatgga ggtcttgacc ttggttaatg gcatattcga taacaggttt
    25261 gtcatccatc atggcatcga tggcaccagc actcaagctg ttgttcatta aatccccagt
    25321 gtcaaatgtt ttaatagtaa aaccgtattt atctttgatt gtttcaagga aacgttgagc
    25381 ggcagttccg tttttaacac caacggtttt gccagttaat tggtcgtact tgctaatttt
    25441 gtgtgacttt gtagtagcaa tgacaacttt tgtatcatag taagtatcag acatggtgaa
    25501 gactttttca cgttctttag tctttgtcat ccctgccatg atagcgtcgg cttgcccagc
    25561 ttgaaccgca ttgactgctg cgtcaaatcc aggataggac atctgaatgt tccagccttt
    25621 aatctcagcg actttgttaa taatgtcaac atcaattcct ttataagttt gatctgaatc
    25681 tttaaactca aaaggtgcat aggcggtatc agaaacaatc ttaatcgttt ctgctttggc
    25741 aatacctaat gagaaaattg ggaataaaat tagcaaaaat gctagaaatt ttttcttcat
    25801 ttttagtctc cttttccgaa tattctctca ttatatcaga aaaagtaaaa aaaggcaaat
    25861 ttttatattt ttcgtgtcag aaaatataac attgattttt tccttttctt gaattgctat
    25921 taaaaagtgc tataataata gtatatatag aagaaaagag gacggggata tgaagaacaa
    25981 aagaatattt aaagacttcc aagcttcaaa aatgagttta aacatttaca caagcccctt
    26041 gttagccttt gtttttgtct tcataggaga gtttgtggct tatactttat atggtattag
    26101 tttgttagct ctcatcggac ttgctagaaa ttttggagag gctggtcaaa atcttgcaag
    26161 ctacttgcag accttgcatc agagcttgac ggataaaaca agtgactttc gtttaatttt
    26221 aggattactg gcctttggtt ttattcttaa cactgtgttc agatggacaa gaaaagttga
    26281 gaaaagacct attcgaacct tgggatttta tagagagaat ttcctcagca atcttctgaa
    26341 aggatttagt ctaggtctgg cactttttct tctgaccttg ttaggtttgg tgctcttagg
    26401 tcaatatcgt ttggaatcca ttcacttgaa tccttattct cttgcctttg tcgtctttac
    26461 tatcccattt tggattttac aggggacagc agaagaagtg gtggcccgtg cttggctact
    26521 tcctcaattg gcctcaagaa ccaatctaaa actagctatt tttatatcta gcctgttctt
    26581 taccctgctt catatgggca attctggcct cacccctcta tcctctagta aatctctttt
    26641 tattcggagt tgccatggct ctttaccttc tcaaaactga tacagtttgg ggtgttgcag
    26701 gtattcatgg tgcttggaat tttgctcagg gtaatctctt tgggatttta gttagtggtc
    26761 aaccgtcagg aacgtctctg atgacctttt taccacaagg caatcaagat tggctatcag
    26821 gtggttcttt tggcatagaa ggttccatta tgacaagtct ggtattacta ctgctgattg
    26881 tctatcttgc taataaatta aagaaagaaa atgaaaggat gtgacttcgg tccgtccttt
    26941 tcttcgtgaa aatactataa gtatgctaaa ataggaatag cacatggaga gaggattctt
    27001 atgatcaatc acattacaga taatcaattt aaactagtat caaaatatca accatcagga
    27061 gatcaacccc aagctatcga gcagttggtg gataacattg aggggggaga aaaagctcag
    27121 attctgatgg gggcgactgg aacagggaag acctatacta tgagtcaggt catttctaaa
    27181 gtcaataaac caactctggt tattgcccac aataaaactc tggctggtca gctctatggg
    27241 gagtttaagg aatttttccc tgaaaatgca gttgagtatt tcgtatccta ctatgattat
    27301 taccagccag aggcctatgt cccttctagc gatacctata ttgagaagga tagttctgtc
    27361 aatgacgaga ttgacaagct tcgccactca gctacctcag cccttttgga gcgtaatgat
    27421 gttattgttg tggcctcagt ttcttgtatc tatggtttgg gttcgcccaa ggaatacgct
    27481 gatagtgtcg ttagtctccg tcctggtcta gagatttctc gtgataaact cttgaatgac
    27541 ttggtcgata ttcagtttga acgtaatgat attgatttcc aacgcggaag atttcgcgtt
    27601 cgtggggatg tggtagagat tttcccagct tcccgagatg aacatgcctt tcgagtagaa
    27661 ttttttggag acgaaattga ccgtattcgt gaagttgagg ctctgacagg tcaggtgttg
    27721 ggagaagtgg atcatttagc gattttccca gcgacacact ttgtgaccaa tgacgaccac
    27781 atggaagttg ccattgcaaa gattcaggcc gagttggaag aacaattagc tgtctttgaa
    27841 aaggaaggta aactgcttga agcccagcgt ttgaaacagc ggacagagta tgatatcgaa
    27901 atgttgcgtg agatgggcta taccaatggg gttgaaaatt attctcgcca catggatgga
    27961 cggagcgaag gagagcctcc ttatacgctt ctcgacttct tcccagatga tttcttgatt
    28021 atgattgacg agagtcatat gaccataggg caaatcaagg gcatgtacaa tggagaccgt
    28081 tctcgtaaag aaatgctggt taattatggt ttccgtttgc cgtctgcttt ggacaatcgt
    28141 cctctccgtc gggaggagtt tgagagtcac gttcatcaga ttgtttacgt ttcagcgaca
    28201 cctggtgact atgaaaatga acagaccgag acagtgattg agcaaatcat tcgtccaacg
    28261 ggactcttgg atccagaggt ggaagtccgt ccgactatgg gacagattga tgacctcttg
    28321 ggtgaaatca atgcccgcgt tgaaaaaaat gagcgtacct ttatcacaac tttgaccaag
    28381 aaaatggcag aggacttgac cgactacttc aaggaaatgg gtatcaaggt taagtacatg
    28441 cactcggata tcaagacctt ggaacggacg gagattatcc gtgacctgcg cttgggtgtc
    28501 tttgatgtct tggtcggaat taacctgctc cgtgaaggaa ttgacgttcc tgaagtgagc
    28561 ctcgtagcta ttctcgatgc tgacaaggaa ggtttccttc gcaacgaacg tggactcatc
    28621 cagactattg gacgtgctgc tcgtaacagt gaaggccatg tcatcatgta tgcagacacg
    28681 gttacccagt ctatgcaacg tgctatcgat gaaactgccc gccgtcggaa aattcagatg
    28741 gcctataatg aagagcatgg tatcgtacca cagacaatca agaaagaaat ccgtgacctg
    28801 attgctgtga ccaaggcagt tgctaaggaa gaggacaagg aagtcgacat cactagcctc
    28861 aacaaacaag agcgaaaaga actcgtcaag aaactagaaa aacaaatgca agaagccgtc
    28921 gaagtgcttg actttgaact ggcggctcag atccgtgata tgatgttgga agtcaaggcc
    28981 ttggattagg ggaatagtat gatttattta agaaagttaa agagagaaga tttgatgtct
    29041 ttatgggaaa tggcttattc acaacttaat ccagtttgga aacagtatga tgctccctat
    29101 tatgatgatt atcagtattt ttcaaatttt aaagaattcg aactacaaaa atcagaatcc
    29161 attttaagca actcaaatcg ccttggtatt tttgttgatg ataaactagt tgggactgtt
    29221 tcgcgttatt gggtatgtaa acaaacaaga tggatggaat tgggaattgg tatttatgat
    29281 aaaaaattct ggaacactgg tattgggaaa gttgctatgt tgcagtggat agataggacg
    29341 tttcaggatt acttggagtt ggagcatctg ggtttgacaa cttggtcagg gaatcttggt
    29401 atgatgaaac ttgctgaaaa attaagaatg aaaaaagaag ctcatattcc aaaagttcgt
    29461 tattatcaag gtaaatattt tgatagtatt aaatatggta ttttgagaga agactgggag
    29521 aaaataaatg acggttatta tcaaatcaat ggaaactcct gaagagatag aaggtaaatc
    29581 cctcgttcac tggcaaacgt ggagagaggc ttatgatgac cttttgcctg cagaatttca
    29641 ggagacaatg acattagaaa gatgtcgact ctttagtcaa aagtatccag aaaatacatt
    29701 gattgcgata ggtgatctga aggtagttgg ttttatcagt tatggtaact ttcgtgatga
    29761 gactattcaa gctggtgaaa ttattgcttt atatgtttta aaagactatt acggaaaagg
    29821 catagcacaa aagttaatga aagcagcttt gactgctctt gatcattttt ctgaaatttt
    29881 cttatgggta ttgaaagata acaagcgagc cattgctttc tatcaaaaaa tgggttttac
    29941 ttttgatgga caagaaaaga tacttgaact tggaaagcct ataaaggaaa aacgaatggt
    30001 attctattct aaaataattt taaaaagtag aagctaatgg cactggtacc aagtctgaaa
    30061 atttaataaa ttagaaagcg agtaaattta tgtcccgttc ccaattaacg attttaacaa
    30121 ccatttgtct gattgaagac ctcgaaacgc agcgcgtggt gatgcagtac cgcgctcctg
    30181 aaaccaatcg ctggtctggt tatgcctttc caggaggtca tgtagaaaat ggcgagtctt
    30241 tcgcggagtc tgtcattcgt gaaatatatg aagaaacagg gttgactatc caaaatcctc
    30301 aacttgtcgg cattaaaaat tggccactag atacaggtgg gcgctatatt gtcgtttgtt
    30361 ataaggctac tgagttctct ggtacccttc gctcttcaga tgaaggagaa gtttcttggg
    30421 tgcaaaaaga ccagattcca aacttagatc tggcctatga tatgctacct ttgatggaga
    30481 tgatggaatc tccagacaaa tctgaatttt tctaccctcg ccgtacagaa gatgattggg
    30541 agaagaaaat cttctagtct tttactaaat aacctagctg atccaaggcc tcctcgatat
    30601 agtggaggtc ttgttgtgtt tcggcttcga ctaggtggta atggatgcca tctgtcaatt
    30661 cagatagagg tctaaagtca gaatgctcga cttgttctag aaaatgttgc acatctctgc
    30721 gacaagacag tttaagcaag gtttcaattt ctccataaac gggatggtca atcaaggtat
    30781 tctggacatg cccaccatta tcgacaatag caaggagttc ctgaccgatt tcttcaactt
    30841 catgtttcac tttgaaaagt ttgtgaacat aaggattggt atcaatttgc ttatagatgt
    30901 agccacgatt ggtggatagg ataggagcgc catcggctct caaaattgca atgtcctgca
    30961 caatgacctg acgtgtgaca tgaaaatgtt ccgccaaact ttggccatta agggctttag
    31021 gagcttcttt caagagttgg agcagggctt gtttgcgatc ttttgtcata gcttttcctt
    31081 ttaacggcgt tttcgaagca ctttatagac agctagtgct aatgtatagt ctaccatact
    31141 atggataatt gtgccaaatc caactagtac aaatagaaca tagaacatgt tttctacatt
    31201 ggtacccgaa gttgcgtaaa aaaggacaca ggctaatact tcagcaaggg catgaacaac
    31261 agccaaaaca aaattgaaaa cccaggaaga ttttggttta tctagggtat cggggaattt
    31321 ttgtaggtaa agagctccta aagcaccaaa agatatatgg gaaaaggccc gaaaaacgat
    31381 aaccatggga tagccagcca tcaaaaatcc aaaactagag gctaggatga caaaaactgc
    31441 catcaagggc gacaagaaca tggctataaa aatagcgatg tggctcccca aagtatagga
    31501 agcaggtgga atgacaatct tgaaaggcat aacaattgga atcaaaatcg caatagccgt
    31561 taaaagggct gtcattgtca taaattgtgt ctttttccgt gtattcacaa gaatctcctt
    31621 tttaactgca tatacactag tatggtacaa taaaccagac aataaagcaa gaatttactt
    31681 gggtttatag atcatttttt agttaaaagt tatagtggat tgaaactaga atagtccacc
    31741 tctacttcta aaacattgtt agaaatcgat ttgactgtcc tgatcgattt gtcctgttct
    31801 tatttcgttt tactatagta aagatttcat taaaaagaaa ctgtatagag caaaatctcc
    31861 accttcaggt ttgaaagcgg agattgtttt tattttttca aggtttgtag tcgtggaaca
    31921 atggctaggg atagaattgc agaaatgacc aattcagcaa ttgaatttgt tgagataacg
    31981 gttgccagaa gaagttggat atttccatta taaacatttc caaataggaa gaagattcct
    32041 ccaaggacaa agatagtatt tgtcaaggaa ccaagggccc cagctaaaat cagaccagtc
    32101 ttgtttttca tcagtttata gactaagtaa ggagttaaac caatcaaaat acgtgggaca
    32161 atggcaatga tagctgagta gatgtttccg tttggtacga agggagagaa gaggtagctt
    32221 gtcggtagaa tcgtaatcgt gttaaccgtc aagctaagta atcccatcaa aaatccaagt
    32281 gtaaccccaa ctcgtggacc ataaataatg ctggcaataa tgacaggaat atgaacaatg
    32341 gtcggtttga ttggaaatgg aaaaaggtta aagataagtg agctcagaaa gtgtatcacg
    32401 agcatggtag caaaaaagat agcaatgggt gcaatattag agcgtttttt catcgatagt
    32461 ttcctttatt ctttctaaaa taattgtgag gtcagctaaa gctcctcgtc cgtggtctcc
    32521 acaagctagt agggattcct taggagcaat cagctgatag ccgtaggttt ctaatgtttt
    32581 cagattattc tgagttactg gatggtcata catttttgta ttcatagcag gagctattag
    32641 tttgggaata tgacttggta gggctagagc tgtactggtt accatgttgt ccgcaaagcc
    32701 gtgagctagt tttgcaatag tgttagcagt tgcaggtacc acgataaata aatctgcttt
    32761 ttttccaagt tcgatatgat tgacctgatc aggatagggt tccttcatga catccaagtg
    32821 gacaggattc tgtgagagta cctgtagtga caaaggttgg ataaactctg tagcagcctg
    32881 agtcattaag acagtgactt gatggccttg tttttttaga gaactgacta aatctgccga
    32941 cttataagag gcgattgaac ccgttacagc caagagaatg tttgccatag ttttcctttc
    33001 taagaatgat aggcttgaat tttttcaagg aggagttctg caatttcttc tttagtctgg
    33061 actgtttgaa gctgattttt ctcaacaaat atagctcggt gctgatctgc tgaaatttga
    33121 gtcaggtcat tcgcgatgat taaatctgct tgattcttga taagactttt tcgtgcaata
    33181 tcaaccagat gatcttcggt aacatcaacc agcagtttga aaccaatcag atgaatagta
    33241 ggattccatt ccttgactag ggatatgatt ttgggtgtct ttttaaggaa caaaacctga
    33301 acctcatcag ttgaagaaat cttggcctga tgattctgct tgcttaaaaa ttcttttaga
    33361 ttggagctag cctgaacttc ctcaagccct gtcatataaa caggagtgta gtcagaaaca
    33421 gccattgagt ggatcaagat ctgataatcc tgaacacgtt cttgcatttc tattagaagg
    33481 tccttggtat tggtaatttc tcgaatactt aggttaggat gagactctgg cttcagagct
    33541 cgttttgtcg taattaaaca aacttcatgc cctgcagaaa gcaaagtttc tgtgataatt
    33601 ttccccaagt gacctgtaga atggttagtg atagagcgga cgctatcgat agcttcactg
    33661 gtaccgcccg atgtaactaa aattttcata gcactattgt acacaaaaat aagcggtaag
    33721 taaaatgaaa gtgataaatt tttggtaaaa acgaagattt attatagttt caaactataa
    33781 agccatataa aatttaagaa aggactctaa aagtcttaaa aacagagata tttacgaacg
    33841 tttagagagt tttaggatgt taaaaatctt gttttgtgat ataatgaatt atcatataag
    33901 aggttagagg aattttgaat gaaaacagat attgaaatcg cacagagtat tgagttgaag
    33961 ccaattgttg atgttgtaga gaaacttggt atttcttacg acgatttgga gttgtacgga
    34021 aagtacaagg ctaaactcag ctttgataaa attcgggcag ttgagagcaa tccagtcggt
    34081 aaattgatct tggttactgc catcaaccca acacctgcag gtgaaggaaa gtcgacgctt
    34141 accattggtc ttgcggatgc cttgaacaag attggcaaga aaaccatgat tgctatccgc
    34201 gaaccgtctc ttggtccagt catggggatc aagggtggtg ctgctggtgg tgggtatgca
    34261 caagttctgc caatggaaga catcaacctc cactttactg gagatatgca tgctattaca
    34321 actgccaaca atgccctttc tgccttgatt gacaaccact tgcaccaagg gaatgagctg
    34381 ggaattgatc aacgtcgtat cctctggaaa cgcgttgtgg acttgaacga ccgtgcgctc
    34441 cgccatgtga ctgttggtct tggtggtcct ctaaacggta ttccacgtga ggacggtttt
    34501 gatattacag ttgcttcaga aatcatggca attctttgct tggcaacgga catcgaggac
    34561 ttgaaacttc gtttggcgaa tatcgttatt ggttatcgct atgaccgtac gcctgtttct
    34621 gtaggtgatt tgcaggttga gggtgccttg gctttgattt tgaaggatgc tattaagcca
    34681 aacttggttc agacaattta cggtacacct gcctttgtac acggtggtcc atttgccaat
    34741 atcgctcatg gctgtaactc tgttttggcg acgacaacag cccttcactt ggctgattac
    34801 actgttactg aagctggttt tggtgcggac cttggtgctg agaaattcct tgatatcaag
    34861 acaccaaact tgccaacatc tccagatgca gttgttattg tcgcaaccct tcgtgccctt
    34921 aagatgaatg gtggtgtggc taaagacgct ctgactgaag aaaatgtaga ggcagttcgt
    34981 gcaggttttg ctaacttgaa acgccacgtt gaaaatatcc gtaagttcgg tattccagca
    35041 gttgtagcta ttaacgaatt tgtatctgat acagaagctg aaattgcagc cttaaaagaa
    35101 ctctgtgcct caatcgatgt accagttgaa ttggctagtg tctgggctga tggagcagaa
    35161 ggtggagtag cacttgccga aacagttgtt aagacaattg ctgaaaatcc agctaactat
    35221 aaacgtttgt atgataatga cctttctgtc caagaaaaga ttgaaaaaat tgtcactgaa
    35281 atctatcgtg gtagcaaagt gaactttgag aagaaagctc aaacacaaat tgctcaaatc
    35341 gttcaaaacg gttgggacaa attgccaatc tgtatggcta aaactcaata cagtttctca
    35401 gacaatccaa atgcgcttgg agcaccagaa aactttgaaa ttaccattcg tgaattggta
    35461 ccaaaattag gtgcaggctt catcgttgcc ttaactggtg atgttatgac catgccaggt
    35521 cttccaaaac gtccagcagc tctcaacatg gatgttgaaa gcgatggaac tgtactaggc
    35581 ttgttctagt ggattgaaat tgactttaag tgagtttgga aataatatcc aagctcattt
    35641 tttctcagac tgcaagcagt tcatcaataa g
//
LOCUS       DAVAGB010000015        34953 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVAGB010000015 DAVAGB010000000
VERSION     DAVAGB010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34953
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.015"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(106..1086)
                     /locus_tag="VQO19_000874"
     CDS             complement(106..1086)
                     /locus_tag="VQO19_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HET1349164.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTLEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(1412..1615)
                     /locus_tag="VQO19_000875"
     CDS             complement(1412..1615)
                     /locus_tag="VQO19_000875"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349165.1"
                     /translation="MKIKEQTRKLTAGCSKHCFEVVDETDEVSSKHGFEVVDETDEVS
                     SKHRFEVADRTDEVSNIYTVRRR"
     gene            complement(1643..3658)
                     /gene="recG"
                     /locus_tag="VQO19_000876"
     CDS             complement(1643..3658)
                     /gene="recG"
                     /locus_tag="VQO19_000876"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HET1349166.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLNGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLDWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3677..4780)
                     /locus_tag="VQO19_000877"
     CDS             complement(3677..4780)
                     /locus_tag="VQO19_000877"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HET1349167.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4770..5138)
                     /locus_tag="VQO19_000878"
     CDS             complement(4770..5138)
                     /locus_tag="VQO19_000878"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HET1349168.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            complement(5177..6208)
                     /locus_tag="VQO19_000879"
     CDS             complement(5177..6208)
                     /locus_tag="VQO19_000879"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET1349169.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRFKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6210..7241)
                     /locus_tag="VQO19_000880"
     CDS             complement(6210..7241)
                     /locus_tag="VQO19_000880"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET1349170.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7322..9835)
                     /gene="secA"
                     /locus_tag="VQO19_000881"
     CDS             complement(7322..9835)
                     /gene="secA"
                     /locus_tag="VQO19_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HET1349171.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(9981..10268)
                     /locus_tag="VQO19_000882"
     CDS             complement(9981..10268)
                     /locus_tag="VQO19_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349172.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            complement(10279..10929)
                     /locus_tag="VQO19_000883"
     CDS             complement(10279..10929)
                     /locus_tag="VQO19_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET1349173.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            complement(10933..11574)
                     /locus_tag="VQO19_000884"
     CDS             complement(10933..11574)
                     /locus_tag="VQO19_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349174.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLILSRLEEKFKKG"
     gene            complement(11567..12358)
                     /locus_tag="VQO19_000885"
     CDS             complement(11567..12358)
                     /locus_tag="VQO19_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349175.1"
                     /translation="MKIPLLTFARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAILTHFFGTFSPLGWNSLFSDGSSLQR
                     LLDGEITSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            complement(12380..12772)
                     /locus_tag="VQO19_000886"
     CDS             complement(12380..12772)
                     /locus_tag="VQO19_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349176.1"
                     /translation="MKIKKLLKMVIPVLMISAVGTTFVEANQIGAFSNFVITTSYKRT
                     GYLTKENEGAEYIMNLNPCRNLHPMTVKHRIVNSNGEARSGESLTTCGTRSTHGNWAT
                     VGYVYAADMARQNWWDLSAAISGSWSPN"
     gene            13099..13950
                     /locus_tag="VQO19_000887"
     CDS             13099..13950
                     /locus_tag="VQO19_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET1349177.1"
                     /translation="MRWDYGQIFKEIRKSKGLTQQDVCGQVIHRTTLTNIEHGKVIPS
                     FENMVFLLEQIDMSLAEFKYICNEYHPSKRRDIIVESQNPSTFQDTRKMVELTEKCQK
                     YLKTHHDVPIQNIYRHTKIVTELRTKGFKNNHVLKDLYEEIWDYLEPMDTWYISDLKL
                     LGTILFFFPSENLPLLIDRIMKTIEKYKYFRETKAFLSSFLANLSTVYFQHHLFKECE
                     TITLQLLVLAEELKIYDILGFSQVRLGILQHNSDLIDKGITLLRLTKEEALVKILEKE
                     INDFSNL"
     gene            complement(14182..14532)
                     /locus_tag="VQO19_000888"
     CDS             complement(14182..14532)
                     /locus_tag="VQO19_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349178.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLAYVFFKKMIRLRRE
                     LGKSKGVHKGRCRN"
     gene            complement(14672..15007)
                     /locus_tag="VQO19_000889"
     CDS             complement(14672..15007)
                     /locus_tag="VQO19_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349179.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(15095..16405)
                     /gene="der"
                     /locus_tag="VQO19_000890"
     CDS             complement(15095..16405)
                     /gene="der"
                     /locus_tag="VQO19_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HET1349180.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPGMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(16419..17132)
                     /locus_tag="VQO19_000891"
     CDS             complement(16419..17132)
                     /locus_tag="VQO19_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HET1349181.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(17129..18025)
                     /gene="dnaI"
                     /locus_tag="VQO19_000892"
     CDS             complement(17129..18025)
                     /gene="dnaI"
                     /locus_tag="VQO19_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HET1349182.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAIGDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKGKNGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(18026..19195)
                     /locus_tag="VQO19_000893"
     CDS             complement(18026..19195)
                     /locus_tag="VQO19_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HET1349183.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLDHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSPKETTIIKEAKSKTTLQFLAEIKQTRKGTTTQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(19196..19669)
                     /gene="nrdR"
                     /locus_tag="VQO19_000894"
     CDS             complement(19196..19669)
                     /gene="nrdR"
                     /locus_tag="VQO19_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HET1349184.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            19809..20174
                     /locus_tag="VQO19_000895"
     CDS             19809..20174
                     /locus_tag="VQO19_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET1349185.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            20179..20874
                     /locus_tag="VQO19_000896"
     CDS             20179..20874
                     /locus_tag="VQO19_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1349186.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            20891..21658
                     /locus_tag="VQO19_000897"
     CDS             20891..21658
                     /locus_tag="VQO19_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349187.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(22011..23210)
                     /locus_tag="VQO19_000898"
     CDS             complement(22011..23210)
                     /locus_tag="VQO19_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET1349188.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGILNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEV
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILVHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINDYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(23207..24100)
                     /locus_tag="VQO19_000899"
     CDS             complement(23207..24100)
                     /locus_tag="VQO19_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1349189.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            24217..24297
                     /locus_tag="VQO19_000900"
                     /pseudo
     CDS             24217..24297
                     /locus_tag="VQO19_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            24807..24995
                     /locus_tag="VQO19_000901"
                     /pseudo
     CDS             24807..24995
                     /locus_tag="VQO19_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            25410..26027
                     /locus_tag="VQO19_000902"
     CDS             25410..26027
                     /locus_tag="VQO19_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HET1349190.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(26347..27234)
                     /locus_tag="VQO19_000903"
     CDS             complement(26347..27234)
                     /locus_tag="VQO19_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET1349191.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(27383..29266)
                     /locus_tag="VQO19_000904"
     CDS             complement(27383..29266)
                     /locus_tag="VQO19_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET1349192.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTGDYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            29642..31096
                     /locus_tag="VQO19_000905"
     CDS             29642..31096
                     /locus_tag="VQO19_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET1349193.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEDKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            31077..32042
                     /locus_tag="VQO19_000906"
     CDS             31077..32042
                     /locus_tag="VQO19_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET1349194.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFTSDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(32078..33352)
                     /locus_tag="VQO19_000907"
     CDS             complement(32078..33352)
                     /locus_tag="VQO19_000907"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HET1349195.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGASDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRMAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVEQLIADKTFNLETAQRYLENLRS"
     gene            complement(33352..34524)
                     /locus_tag="VQO19_000908"
     CDS             complement(33352..34524)
                     /locus_tag="VQO19_000908"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HET1349196.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(34655..34903)
                     /locus_tag="VQO19_000909"
     CDS             complement(34655..34903)
                     /locus_tag="VQO19_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349197.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
BASE COUNT        10335 a         7780 c         6483 g        10355 t
ORIGIN      
        1 attttactat atttccatga taaaacgcat agtatcaagt tctcttaatc ccctgatact
       61 atgcgtgttt gtaattttta agattttgtg cttagagtcg actccttatt ttagatattt
      121 aaaaggaatc tcacttccac agagccagtt gtagacttgg tcattaacaa atacattcat
      181 ggcttcgtga gcatactcag gcatgatacg ataggtttta tcgcaggtca gacgattata
      241 aatcgcaaac tgggtaatgg gatagcaaac atcgtcgtcc aagcccgtaa tcatcttaac
      301 ctcaccttgg atacgatggg caagattttt gacatcgata taggcaaggg tcgccatgat
      361 ttcctcctct gtttcatgga aggggtcgtg aaacttgaaa taacggaaaa gttcgtcgta
      421 agcctcgcta gtattaccaa tctcaatcac ccgtctgaag tctgacaaga agggataaat
      481 ggcaactgtt ttctgaattc gaggattgag cgctgctgca actagagcta gagcccctcc
      541 ttgtgaggca ccatagctag aaagacgctt ctcatcaacc tgagacagac tagcaacaat
      601 ttcgaccaac tggtaaatat ccagataaac atccttataa aagaggtggt cccgaccttc
      661 catagcacca cggataatat gccccttaac cgtatttcct aaaggagaac gcaagccgtc
      721 ttgtgagtaa cctgactggc cccgcacatc catggaaaca acaccgtaac cagctacggt
      781 gaagcccagc atgtcggccc agtcccagcc acgtcccata taaccatgaa aatggaagat
      841 tagtggaacc ttctcctcac tctttggaag aacaatgcgt gcatagacct ttccttcctt
      901 gcttccttcc aatgttaact catagcactt gacttgagga atgtggaaat ctctttcctc
      961 caagtggtag gatggaagcg tggaaacatt tttcacttcc ccatcccaga aagcatcaaa
     1021 gtcttccgga acctcatccc ttcctctata ggtcttaatt tcttctagca aagctggatt
     1081 tttcatagca tgctcctttt attttgtaat cgttaccaca actgtagcat atctatgtaa
     1141 tcaatgcaag aaagaaggat aaatagaaag tgaatttaga ttctttactt ttaggatgat
     1201 gggctgaaag tagttttaga aacgaaaaag agcatttcgc tctctcttct gtttatacta
     1261 gttttttgct tccttctttt ggaaagtggt ttggtaattt actttaatcg ttactgtcat
     1321 atgagagtcc tcgtttcttt ttgatgactt tagtataaga gccaaaccta aaaactagct
     1381 taatactctt cgaaaatctc ttcaaaccac gtcagcgtcg ccttaccgta tatatgttac
     1441 tgacttcgtc agttctatct gccacctcaa aacggtgttt tgagctgact tcgtcagttt
     1501 catctacaac ctcaaaacca tgttttgagc tgacttcgtc agtttcatcc acaacctcaa
     1561 aacagtgttt tgagcaacct gcggttagct tcctagtttg ctctttgatt ttcattgagt
     1621 ataagttttc cttagagaaa gcttaatcca gatgttcttt cttttccaga tgaagggcaa
     1681 tcatgcgcca ctctggatct tcttgccaag cttctataga actaatgtag ctagcaacct
     1741 ttcttgcttc ttctaaaatc ggaaaatctt cgataatatc agccacttgg aactctggaa
     1801 gtcctgactg tctggttcca aaaatctcac cagaaccacg cattttcaaa tcttcctccg
     1861 caaggacaaa tccattggtc gtttctgtca tgatgcgcat gcggtctttc ccagaatccg
     1921 tcttgggatt ggcaacgaga acagcgtagg actgcttgtc cccccgaccg acacgacctc
     1981 taagctggtg aagttgactg agaccgaagc gatcggcatc catgataatc atgacagtcg
     2041 cattgggaac gttgacccca acctcaataa ccgtcgtcga aaccagaata tccgtctttc
     2101 tctccttgaa atcctgcatg atctggtctt tttcgtcact cttcatccta ccatgtagaa
     2161 gagccacctc tgccttgcct gcaaaatgag tcgtcaactc ctctgataag gcaatggcat
     2221 ttttcaaatc tagagcttct gattcttcaa tcaaaggaga gatgacatag gcttgggaac
     2281 ctttttgaat ttccccctct aaccaagtca agacctgagg tagttgctca tgtttgatcc
     2341 agcgcgtcac aataggcttc cgacctgctg gcatctggtc gataatggaa acatccatat
     2401 ctccaaaggc tgtgatggca agcgtccgtg gaatgggagt cgccgtcatc atgaggacat
     2461 ctggattgtc acctttttcc cgtaaaatac gcctttgccc tacaccaaaa cggtgctgct
     2521 catcgataat aatcaaacca agacgagcat actccacccc atcttgtatc agagcgtgag
     2581 ttcctataat caaatcagcc tcacccttgg caatggtctc caagacttct ctcttttctg
     2641 cagctttcaa ggaacctgtc aagagagcca gtttcaaatt gggaaaaagg ttctgtaaac
     2701 tctcaaagtg ttgctctgcg aggatttctg ttggtaccat tagggcagcc tgataacctg
     2761 ctgtcactgc cgcaaacatg gccaagccag cgactaccgt ttttccactc cccacatccc
     2821 cttgtaggag acgattcatg tggtggtcgg acttcatatc agttaaaatt tcctgcaaac
     2881 tcttttcctg agcttgggtc agggcaaaag gaagacttgc tttaactgct gtcacttttt
     2941 cctgagacca atccagaacc agaccacttc cctgaactct attttcagac ttgagcatct
     3001 gcagctgcat ttggaaataa aagagttcct caaactttat acggcgaaga gcctgcttgt
     3061 attctgccaa atcctttgga aaatgcatag ctcggactgc ctgacaacgg gacatgagtt
     3121 tgtatttgtc tagtaaagac tggggcagat tttcttctat caagaggtcc agtccctgat
     3181 caaaagccgt cttgatgacc ttaaccagac tggcctgact gattccctga gccagacgat
     3241 aaacaggctg gaggtcatct tctacctgag ccagaacctt catcccattc agactagcct
     3301 tagcgcggtc ccattttcca aagacagcaa gggttgctcc caactctatt ttatcagcca
     3361 gatagggctg gttaaagaaa ttcaccgcaa aaacgacctc tccctgcttg agactaaaac
     3421 gcaggcgatt gcgcttgaaa ccataatact ggacactagc aggagtcact acctgaccag
     3481 aaagaactgc cttctcaccg tcttccagct ccagcacctg cttggttttg aagtcttcat
     3541 aacggaaagg aaagtagagc aagagatctt gcaagttttc aattcctagt ttggcatatt
     3601 tttctgctga ctttggtccc acaccaggca agacatgcaa gggttgatgt agattcatgc
     3661 tccactcctt tcttttctaa taatattctc tcggaatacg gtcgctgagg aggcaaacca
     3721 cctcatagtt aatggttacg cggtaggtcg ctacctgagt tgcagtgatt tccttatccc
     3781 cattggagcc aatcaaggtt accttggttc cgagtgggta aggcttaggc aatcgaatag
     3841 tgatttggtc catcgaaacc ctgccgacaa ttgggcaagc ttggccatct accaagacag
     3901 agaaattttg catgtctctt gtccatccat ctgcataccc gattggtacg gtcgcgatga
     3961 cttgctcgct atccgcttga taagttgctc catagcccat gcaagctcca gctggaactg
     4021 tcttgacatg aaccagagca gactccaagg tcaaggccgg tatcaaatca taaggcaaat
     4081 ccaagaccgc tccacttgga ttgaggccat acatggcatc tcccatacga accgcattga
     4141 aaatagtctc tacatgccaa agagtcgttg cagaattgct agcatgaacc agctctggaa
     4201 cttccttcat actagctaaa atagttttaa accgttctaa ctgggcatta aaatagtcat
     4261 ctgattcctc atcagcagta gcaaagtggg taaagattcc ttcaacacga acaccgtgtt
     4321 gttggagcaa atcttgagcc tgctcaacct cactggcctc tctaaaacca atccgtccca
     4381 tccctgaatc aatcttgagg tggactgtca atccagttag gtccacttcc ttatctaaga
     4441 gtgcttgaat ccactccagt ccagccactg tcaaggtgaa gtcatattct ttagctagag
     4501 caacagcttc gatttcagaa actcctaaaa tgaggattgg cttgctgagt ccagcttgtc
     4561 tgagttcaat ggcttcatcg atattggaaa cgcaaaagcc atcaacatca tcttgaattg
     4621 ccttggcaac ggcaacagct ccatgaccat aagcattggc cttgaccaca gccaacttga
     4681 gcgttccttg agggatatga gcccccattt gctgaatatt ttgtcgaata gctcccagat
     4741 gaatcagagc cttggttggt ctatgtggac tagctttcat gattttcctc caaaatgaca
     4801 ctggctgtca caaactgatc ggtgtggctg atagacagcc aaatctttcc tgaaaatggt
     4861 gcctgactaa aataaggcgc cccacgttca ttgttcaaga cttccaaatc ctgaaaaccg
     4921 agcttgctaa tgcccgttcc catagccttg gaaaaggcct ccttagccga ccagcgacca
     4981 gctaaatatt ctatttgcct gcgtcctttg agactggtga agcgctccat ttcctgagcg
     5041 gtcagtacac gcttagcaaa tccttcatgt cgtgtaactg cgctttctat cgaagccaat
     5101 tcttcgatgt caattccgtg tccaactatc attctcatca aaaggagttg agattcccca
     5161 actccatcct tttcacttat tttgtcaagg taacataaat ctcttctacc aaggcctctg
     5221 tattttccca acctaggcaa gggtcagtaa tagagcaacc aaagatctct ggttggtttt
     5281 gacgaccatc tgctaggtaa gattcaatca taaatcctcg aaccgtcttt ttaattttct
     5341 cattccaatc acgattctgc aaggtctggc gaacaattcg aatctgctcc atatattgct
     5401 tgcctgagtt atcatggttg gtgtcaatga ggataaaagg attttcaagt cccatggttt
     5461 catagcgttc aatggcttgg agtaggtttt catagtagta attcggcata taattgccat
     5521 actcgttgac tgctccacgg aggataacat gggccaaagg attacctgat gtctcaactt
     5581 cctgcccatg ataaaggaag gtttgcttgt tttgagcagc atagatggcg ttaaacataa
     5641 cacccaaatt tcctgaggtt ggatttttca tccctactgg tgcatcaatc ccagaagcca
     5701 caaagcggtg ctcttggtct tccacagaac gagctccaac ggcatggtag ctgaccaagt
     5761 catccaccaa gatcagattt gacggataaa gcatctcatc tgccgttgtc aaaccagtct
     5821 ctgtaatcac gcggtagtgc aactggcgca cagcctgcaa gccgttaatc aggcttggag
     5881 ccttagaagt atctggctgg tgaaccaatc ctttatagcc gtctccattg gtacgaggct
     5941 tagcagtata cacgcgcatg accatgaaaa tcttgtccgc taccttcttt tgcaaggcgg
     6001 ataaacggcg agcatattcc aagaccgcct cttcattatc agaagagcaa ggaccaatca
     6061 ccaagagaat acggtcatct tcccctgaaa taatatctgc caattccctg tcacggcttt
     6121 ccttgaatct caaggcttct gcagacaatt gggtttcagc cttgatgact tccatatcga
     6181 tttcttgacc tttttcaata aatgccatct tattctccta acgttttgta aatttctctg
     6241 acaagagctt ctgtgttatc ccaacccagg caagggtctg tgatagactt accaaatact
     6301 tctggctcat tttgtcgacc atcttccaga taagactcaa tcataaaacc acgaacgaac
     6361 tgcttaattt tttcattcca agcacggtta atcaaggtct ggcggacaat tcggatctgt
     6421 tcaatatact gcttaccaga attgtcatga ttggtatcaa tgatgataaa aggattttcc
     6481 aagcccattt tctcatactg ggcaatggta tcaattaaat tgtcataata gtagttggga
     6541 atattttttc catactcatt aagagcacca cgaagaatag cgtgtgaaag cgggttccca
     6601 gttgtttcta cttcttttcc taagaaaagg aaactttgtt tgttttgagc agcataaatc
     6661 ccattaaaca tgacattgag atttccagag gttggatttt taaaaccagt agaaaatcct
     6721 gccccacttg ccacaaagcg gtgttgctgg tcttcaactg aacgggcacc aactgccatg
     6781 taagaaatca aatcatctac aagcggaagg ttttcaggat aaagcatttc atcagcagtt
     6841 gtcatccctg tttctgtgat gacacgatag tgaagatggc gaacggcttt gattccattg
     6901 ataagactag gcgcttctgt cgcgttaggc tggtgaatca agcctttata gccatctccg
     6961 ttggtacggg gtttggcagt ataaacacgc ataaccataa agatacgatc tgccacttct
     7021 tcttgtagga ctgccaaacg cttagcgtat tcaaggacag cttcttcgtt atcagatgag
     7081 catggcccga ttaccaagag aattcgctgg tcttctccac gtataatggc ttctagctct
     7141 tgatctctct gtgatttcct ctccaaagcc tgaccttcta attttgacaa ggcacgaact
     7201 tcttctatat ttattttaga gctttttgct gtaaatacca taactcatct ccttataaag
     7261 caaacggata cccagtaaaa atttactttt cacaagatat ccgcctctaa actatctcat
     7321 tttattgtct tttaccgtga cagtttttaa atttcttacc agaaccacat gggcaaagtt
     7381 cattgcgtcc aatctggctc aaatccaaat cttctggcat acttgcttgg tgagcagcga
     7441 tattgcgagt cgctgttgta ctgatatgac gttctgcctg tggtctttct tgttcatgaa
     7501 tttgtgcttt catcatcaag cgtgtcacat caaactcaat cgaaccaatc atatcattaa
     7561 acatacggaa accttctgcc tgatactcaa caacagggtt gttctgagca tagccacgaa
     7621 gtccaaccgc gttacgcaat tgatcaaggg catcgatatg atctgtccac ttgttatcca
     7681 ccactcgtag aatcaaaact ttttggaatt ctttaactgc ttcttcatcg cgtagttttg
     7741 aaacctgact atcgtaaacc ttcaaggcac gttggaaaag ctcttccttg atggccttat
     7801 cagacaagcc tgacaagtct tccatcgtaa tagaatcttc aggaagcaag ttgtacttag
     7861 caaagttcaa aattgcctct agtttttcat cttgtttggc acgcgcatga ccatcaacga
     7921 cacgttcaat cgtgcgctta atcatagact gaatttcagg tgccaagtca cgatctgcag
     7981 tgatgacatc gtaacgttga gcatagataa tctcacgttg ttcacgcatg acatcatcgt
     8041 attgaaggac ttgtttacgg gtatcgtagt tatttccttc gacacgtttc tgagctgctt
     8101 caacctgacg cgtcaacatg cgagactcaa tcgcctcttc agacatgttc aagcgttcaa
     8161 agattccctt caagcgttca gaaccaaaac gtttcatcaa atcatcttca agagataggt
     8221 agaattgtga ctcacctgga tctccttgac gacctgaacg tccacgaagc tggttatcga
     8281 tacgacgact ttcatgacgt tctgtaccaa taacacaaag tcctccaagt tcacgaacac
     8341 cttcaccaag cttgatgtcg gtaccacgac ccgccatgtt ggttgcgatg gtaacggcac
     8401 cacgttgacc agcattcatg atgatttggg cttctctata gtggtttttg gcattcaaga
     8461 cttcgtgagg aacaccagct gcaaccaatt tcttagaaat gtagtcacta gtttcaaccg
     8521 ctactgtacc aaccaagaca ggttgaccct tttggtaacg agccttaacg tcttcgacaa
     8581 ccgctttaaa cttagattct atacttgcat aaagaaggtc tgagtggtca atacgttgaa
     8641 caggacggtt tgttgggatt ggaataacac gaatgttgta gatttcacgg aattcttctt
     8701 cctcagtctt acctgtaccc gtcataccag acaatttctt gtacatacgg aaaaggtttt
     8761 ggtacgtgat tgaggcagat gtcttggttt catcctggat tggcacacct tctttggctt
     8821 caatagcttg gtgcaatcca tcagaataac gacgaccttc catggtacga cctgtaaatt
     8881 ggtcgacaat caagatttct tgctcttcgc tcaccacata gtcaatatcg agaagcatga
     8941 tgtagttggc acgaagggcg ttatcgataa agtgggtcaa agccacgttt tcgatgtcat
     9001 agaggttttc aagtttgaag tagctttcag ccctgtcaat ccctgaatca gacaaaccaa
     9061 tagtcttaga ctgcacatcg atgatgtagt catctttgtt caaagatttt acatagtggt
     9121 ctgccatgtg atacaactga ctggtttcaa ccgcattggc acctgataca atcaaaggtg
     9181 tacgagcctc gtcaatcaag atagagtcaa cctcatcgac caaggcatag ttaagcggac
     9241 gttgtaccat gttttcagcg cgaacgacca tgttgtcacg aaggtagtca aatccgattt
     9301 ctgagttagt tgagtaagta atatcacact cataggcttc ttttttctcc attggagatt
     9361 tggtagccaa gttaatccct actgacaaac caagccaaga gtacaattca cccatctcag
     9421 tcgcgtcacg ttctgacagg tattcattaa ccgtaactac gtgaacccct ttacctgaaa
     9481 gggcattgag gtataccggc atggtcgcag tcaaggtttt cccttcccct gtacgcatct
     9541 ctggcacgtc accatggtga agaacaatcc cccccatgac ctgaacctta taagggaaga
     9601 gacctaggac acgtttggca ccttcacgga caaccgcaaa tgcttcgtaa agcaatgaat
     9661 ccagtgattc tccattttga taacgttcct taaattcaac tgtttttgct tttagttggt
     9721 cgtcagtcaa agcagccatt tggtcttcgt atttgaaaac cttgtcagcc atcttttcca
     9781 gacgacggat ttctccttta tcattttcga taattgtttt taaaatatta gccatgtttt
     9841 tccttacttt aaattccgaa tattttagaa tgttccttta attttagcac aattactgat
     9901 tattttcaag gaagaatccc cattttgaaa aggaaaaaga ggttagtttt caagctaacc
     9961 tctccgactt ttatgactgt ttaattgcca aaaatcggca aaatggcaaa tgtgataaat
    10021 aagttaatcc aaagagaaag acagcaaatc agtccaaaaa caaagagact gactttcttg
    10081 gacagcaagg ccatcaaaat ggacagaatt ccaaaaacta gcaagacttt ctgtatgatg
    10141 aagatgtcaa tccttacccc cagaatcgct ctatcccaag ggataaagaa gaaagacagc
    10201 cagatcagca gaactaaacc aatataaacc ttggaatagc gtgtaataaa tgattttaga
    10261 tgtgccataa gccatctcct aggattgtat atcctttaca tattgtatat gtccattttc
    10321 gacaactaat acatctgtac aaaggtctga aatatcttcc gatatgtgcg acgtcaggat
    10381 aaccagacca ttttcttttt tcaggtaaga taaaatgacc tgtttggtta acctcacact
    10441 tttctcatcc aaagcattca taggttcatc gagaaagagt atagaaggag aggaaataaa
    10501 ggcttgaatc aaggccattt tttgctttgt tcccaaggat aaatgacggt attcaacatc
    10561 ttcaaattcc tgtaaatcat agtattgaat ccaataggca attctttttt ccgtaacttt
    10621 agatgaaaaa taccttaaca gttccaaatt ttctctcagg gataaatgag ataaaaactc
    10681 gactttttca attaaaattc ctgcatcctg aatataatga ttttttaccc cgtaaacttt
    10741 accatcttga agaacttttc ctttgtcaag cttaatataa ccagcaagta tctttaaaag
    10801 aaccgtcttg ccagatccat tatcaccttt aagtccataa atttttcctg attgaaacac
    10861 caaattcaac tgatttaaaa taggtctttt cccataaatt ttctgtccat ttataatttc
    10921 aagtctcatc gtttatcctt tcttaaattt ctcttccaag cgactaagaa tcaacataac
    10981 taataagctt aagagtacta aatacactgt tacaatatga tccatcatcc attcttgtcc
    11041 cacaaatgcc aaaaaataga gaaaaaaaga aaaaccagcg cccgcactaa tcagtgctat
    11101 cagataagac agtagtaagt acaacatcat taactgagca agtaaaaaga aaagtgcgac
    11161 tgttttgaaa tgaattccta gcggaagtaa accaagaaac cagacaaaca aatcttgagt
    11221 aaaaaattta gaaatgacaa ccaatcgttt ccttgtataa tcgaaaaagg agcttgattg
    11281 atagcgaatc aagtgatggt aatggtctgc caaatcactt tcaagtaaaa tgacagagag
    11341 ccatcctacc atgaaaagcg aaaggtttaa caagagtttg gggatttcta aattcgcttc
    11401 agaatagtca ttataggaaa aaattgaaat caattctctc ttgaaaaaga taacagcatc
    11461 ctgcttttga accgctgttg acaatagatg gtttatcaaa atcatcatca gaactatacg
    11521 aagtagtaaa acaatctttc tctttagcaa aatattgtta aaattcttaa acattatctt
    11581 catatttttc aagcaccatg taagggacaa tataaaggat ataaggagta aagagtttca
    11641 tcaaacttac atccccatag ctagcttgca tcaaactcgt cataggaacc atatagtaag
    11701 gcaaggcact atagagcagc atagaaccaa gccaaagaaa catcaaatag gtgattgccg
    11761 aacgagtcac attccccaca taatcaacta tttgtaaaaa atagattgca ttgatgaaaa
    11821 taccgattag taggacacaa gtaaagaaca aatagcttgt tatctctcca tctaggagcc
    11881 tttgtaaact actcccatca gaaaatagag aattccatcc aagaggagaa aaagtcccaa
    11941 agaaatgagt taaaattgca attatcagca cagtcactaa atatatcaaa caagggatac
    12001 ttgcaacttg caaagtcaac tttcttttta acccttgata actcacttct cttccaatac
    12061 tcaatcgtaa aactttattt ttcagctcaa tatattgaaa acctagcaaa acaatgatga
    12121 ttggaataat aaatgattga taaaaaccta gattgaactg gagaatacga aaatctaatg
    12181 ctgattttaa taagtcattt ttaattgctt gtccatcgaa tttagctaga tcgggcgcat
    12241 gaatatcaaa aaagaaataa gtcatcaaaa catcacgata aaccaaagca agaaaaagca
    12301 aagtaagcaa gacataaaca aatttatgcc ttgcaaaagt taagagagga atcttcataa
    12361 attataccta ctttacgaat taatttggtg accaactacc tgaaatggca gctgataaat
    12421 cccaccaatt ttgtcttgcc atatctgctg cataaacata gccaaccgtt gcccaattac
    12481 catgagttga acgagtacca caggttgtta acgattctcc actacgagct tctccattag
    12541 aatttactat acgatgctta acagtcatgg gatgtaaatt tctacaagga tttaagttca
    12601 tgatatattc cgcaccttca ttttctttag tcaaataacc tgttctctta taactggtag
    12661 taataacaaa attactaaaa gcacctatct gatttgcttc tacgaaagta gttccaacag
    12721 cacttatcat taaaacagga ataaccattt tcaataattt cttaattttc attttttctg
    12781 tttcctttca ttttttattc aagaagattc cttataactt ctattttaaa tatagactta
    12841 ttctaaacga tggtatatca tacaaattcc tcctttactt attatatata gactctaatt
    12901 tctttatccc caaaaccatg tttcaaacca gataagttga atccaactcc aaatcaaaaa
    12961 tccagagttt ttcggtaaat tcttcaaata ttttttaaag cccatgactt tttccctcct
    13021 ttttgatata ataataccac ctttttctac gttttttata aatgtagaaa atattcacat
    13081 ttacctagga ggaacaatat gagatgggat tatggacaaa tttttaaaga aattcgaaag
    13141 tcaaaaggat tgacccaaca agatgtatgt ggacaagtca tacatcgaac aactctaaca
    13201 aatattgaac acggtaaagt tattcccagt tttgaaaaca tggtatttct tcttgaacaa
    13261 attgatatga gcttggcaga attcaagtat atatgcaacg aataccatcc tagtaaaagg
    13321 cgagatatta ttgtagagag ccaaaatccg tctacttttc aagatactag aaaaatggtt
    13381 gaactcactg agaaatgtca aaaatatctt aagacacatc acgatgttcc tattcaaaat
    13441 atctatcgtc atacaaaaat tgtcacagag ttacgaacta aaggattcaa aaacaaccac
    13501 gtcttgaaag atttgtatga agaaatttgg gactatcttg aacctatgga tacatggtac
    13561 attagtgatt tgaaattgct tggaaccatt ctctttttct ttccttctga aaatcttccc
    13621 cttcttattg atagaattat gaaaaccatc gagaaatata aatacttccg agaaacaaaa
    13681 gcatttttat catctttttt agccaatctc tccactgtat attttcaaca tcatttattc
    13741 aaagaatgtg aaacaatcac cctacaactt ttggtattag cagaagaatt aaaaatatac
    13801 gatattcttg gattctctca agtacgcttg ggaatactac aacataactc cgatttgatt
    13861 gataaaggaa taactttatt acgactaacc aaagaagagg cattagttaa aatactcgaa
    13921 aaagaaatta atgatttttc aaacctataa tttgtaataa ctctcatcat tttattatag
    13981 tagattgtaa tagaatgtaa tagaatgtga acgaatcaat taggggatct aaagcatttt
    14041 ataccaatgt tttataagtt gtattgtatt attccatatt caatccacta tacaagatga
    14101 atatttctct caagtttcat aatcaaaata aaaatgactg tatctatagc tccataaaca
    14161 aatcatagat acagtcattt tttagttcct acaccttcct ttatgcacac ctttagattt
    14221 ccctagttcc cgcctcaagc gaatcatttt tttgaaaaag acataggcta accaatcact
    14281 agcaaaagcg ataagtagta ataatagcca aataccccat aacttgatat ctgtcaaatt
    14341 tctcaagacg atattgaaaa acagaactga aaaaactgtc caagcaaggc taaaaagagc
    14401 atagagggtg atgtaaatcc agtaaaaata gtaaaaaatt gggaaaaatt tactttctct
    14461 attatccttg tcaatccagc tgaaaaagta aaaacagggt aataagatta tcattttaaa
    14521 caagtgttcc atcacaagcc tcctttttta aattgttttc tttagtttcg ttctattaaa
    14581 tgttattacc aatataaacc ttggaatagc gtgtaataaa tgattttaga ggtaccataa
    14641 gccacctcct acaaatagaa accgatataa atcaatgcct tccaccctta gacttcccta
    14701 gttcctgtct caagcgaaac atttctttga aacaggaata agttaaccaa ttcataccaa
    14761 tagctagcag aataaaaaga aaccaaatgc cccataactt gatatctgtc acatttctca
    14821 agacggtatt gaaaaacaga actgaaacaa ctgtccaagc aaggctaaaa agagaataga
    14881 aggggatgta aaaccagtaa aaataataaa aaattggaaa aaacttacta tttctgttgg
    14941 ccttttcaat ccagttatca aaataaaagt acggtgctaa aagtaagaat ttaaacaaat
    15001 gttccatcac cgacatcccc cttcttttga tagcgttttc tattatttta ttatatcaaa
    15061 aaaatccgga actgtcattc cagattctac ttttttattt gcgttttctt gcgatgagat
    15121 gaatcggtgt tccctcaaaa acaaaggcct tgcggatttg attttccaag aaacgtaggt
    15181 aagaaaagtg catgagttct tcttcgttga caaagataac aaaggttggt ggtttggttg
    15241 ccacttgggt cgcatagaaa atcttgagac gttttccttt gtctgtcggt gttgggttga
    15301 tggcaatggc atccatgatg acatcgttca agacagctga tggaatacgt gtattttgac
    15361 tttcgctgat ttgcttaatc atcccaggaa gtttgtggag acgttgcttg gttaaagctg
    15421 atacaaagat aatcggtgcg taaggcaggt attggaactg ctcacggata tcttcttccc
    15481 agtttttcat agtgtggtta tctttttcaa gcgtatccca cttgttgacc acgataatca
    15541 tccctttacc agcttcatga gcaaatccag cgatacgctt gtcgtattca cgaatcccct
    15601 cttccgcatt gatgaccatt aagaccacat ctgaacggtc aatagcacgc atggcacgca
    15661 tgacagagta cttctcagta ttttcataaa ccttaccaga cttacgcata ccagccgtat
    15721 caatcatggt aaactcttga ccatctgtat ctgtaaagtg ggtatcaata gcgtcacgag
    15781 ttgttccagc aacaggactg gcaataacac ggtcttcgcc caagatagca ttgatcaagc
    15841 ttgattttcc aacgttagga cgaccaatca ggctaaactt aatgacatct ggattttctt
    15901 cctcatattc atttggaaga ttttctacga tagcatctag tacatcccct gtaccgattc
    15961 catggacaga tgagataggc agtggttcac ccaaaccgag agcatagaaa tcatagatat
    16021 catttctcat ctcagggttg tccaccttgt tgactgcgag gataactggt ttgtgggtct
    16081 tataaagctt acgggctacg tattcgtctg catcggtaat tccttcctta ccggacacga
    16141 caaagacgat aacatctgct tcttccatgg caatttctgc ctggtgcttg atttgttcca
    16201 tgaaaggagc atcgacatca tcaattcctc ctgtatcaat catgctaaaa gaacgattga
    16261 gccactcacc cgttgcataa atacggtcac gtgtcactcc ttcgacatct tctacaatgg
    16321 agattcgctc accagcgatc cgattaaata gggttgattt cccaacattg ggacgtccta
    16381 caatggcaat agttggtagg gccataattt ctcactttct acaataattt cttctgttca
    16441 agattttttc tagttgagct tggttcagct tgaccaaact gttctgctag gcgctgactc
    16501 cagcttgtgg tcgcacgcgc cccagcatag tcagcctgaa cacggtcata agcttggatt
    16561 gcctcagttg actgttcttg gtattcttcc tcaaagacaa cattctctag tggcagtctc
    16621 ggtttcatat catgatgttg atttggcaca cccagtgcca tcccaaagac agaataggtg
    16681 tagtcaggca ggttaaagag ctctgccact tcttcagact tgtatcgaac caaaccgata
    16741 atcacaccac catagcccaa gctttcagct gccaacaagg cgttttgtcc agcaagagct
    16801 gcatcgaccg aactaatcaa gagaccttcc acaccttggg gttggaaggt gtcggtatga
    16861 agtcgggctc ccttttctgc tcggttcaaa tctccgacaa agagaaggaa aacagcagac
    16921 tggcgaatgg cttcttgagg taccaattca tacaaggcat ctttcttctc ttgacttcgt
    16981 accacaatca cagagtagga ttggaaattc ttccaagatg atgccatctg ggctgctgtc
    17041 aaaatctcat ttaagtctac ttggggaatt tcttgctctt taaacctgcg cactgaagta
    17101 tgagccttca tcaatttaat ggtttctgtc atcgacggtt tactccttct aaacgagtct
    17161 cctcagccaa ataacggatg cgttccatga cccgtctggc ttcccaggtt tcgtcatttc
    17221 catttttccc tttagcgaaa tgcttctcca aatcttcaaa gttgaagtta gaggtgaaaa
    17281 aggtcggtaa attttcctgc atccgatatt ggagaatgac ctgtaggatt tcatcacgca
    17341 cccaagcggt ggattgctcg gcaccaatat catctaaaat caggacttca gaaagcttaa
    17401 tctcatccac taaggtctta acattgccat caccaatagc atttttgaca tcaatgacaa
    17461 agctaggata gtggaggaga gtggatgata caccacgttt ttctgataaa tcatgagcta
    17521 gggcagccac catgaaactt ttacccacac caaagtctcc atacaagtaa agaccttttc
    17581 gaatagctgg atattgctcc acgaaggcta gtagcttttc aaaaactggt aagcgcccca
    17641 aatcatccaa gtcaacttga gccaaactag ctttcttgag actggctggt agattgatta
    17701 acttgagacg gttcttaata gccgcttctt tttcagccgc gattagctca ggagtttctt
    17761 catatgaaac atctgcatag ccatgattct taaccaaaat cggcttgtag cctttggcaa
    17821 tataatccgt atccccacgg agaaacttgt cacgctcggt gatgtactga ttaaacttgg
    17881 agatactgcg atttaattcc tctggagtca aggattcttg ctggataaaa gccgcaacat
    17941 cagggtcctt catgattttc tggaccaaat cttgataata aaaacggctg ggttgacgtt
    18001 tgagtacgtc tccgacactt tccatctaat ctcctccttt ttctaatcga gctaatagtt
    18061 cttgcttctt acgttctagt tccagacgag tttcctcgct ggtttcattc ttatattcag
    18121 gattactcca tttaggaaca ttggttttta ctggggcagt ctgattctgt ttttgtgttt
    18181 ttgctttctg tcctcgctca cggatgcgca agactgcctc ttctgccgaa tgaatctttt
    18241 gataggcata gtcattggct accttcatgg catatttctc attgatattt gccgaatcga
    18301 ccttattaaa ggtcaataaa agaatgatat tgatgacttc gtccagcaag cccaagccag
    18361 ccatctgttg caagagttct ctttctgttt gggtagtggt tcccttgcgt gtttgcttga
    18421 tttctgccaa gaactgcagg gtagttttac ttttagcttc cttgataatg gttgtttcct
    18481 taggactaaa gtccgaggaa actggttttt gagcaatttt ttcccgcatg cgtttggttg
    18541 aaataacctg ggaaacagct gttgacttgg ccaattgata ggtctcaaac caagtccact
    18601 tcttctcctc agcaatagca aacaagttca agacatcaga ctgctcatcc gcaaaacgaa
    18661 gtccatctcg agccatcagc tgacgaaaat gatccaagtc aaaatcattg gccactttct
    18721 tcttgagacc aaggtcttct tgactgccta gttctgccaa ttctggaaag acttgattga
    18781 gtgagacagg tatttcttca ccatcagcac tttcaacttt caaatcctcc acagcagagt
    18841 cgccaatctt tttctctaag agtctgcgat aaacaggatg ctccaagaag tcttgactag
    18901 atagaggagc atggagggct agctgataaa catccccctt ttgatagagg gtcaagagat
    18961 taaaagcaga taagattttc aatgatttta tcagtctatc catcccaaag ttgagatgat
    19021 tgaggatact tgaaaaaaga tattcctttc taccattatc ccaaaaactg attgtataaa
    19081 gataaaggct cagtgcctcc tgaccgataa tcgggaggta gcactgtacc agagatgagg
    19141 tatcttgcga cacccgatta ttctttagat aagaaaaacg gtcaattggc ttcatttatc
    19201 tttccttttt ctttttagag gactgggtga tttgttggag caagctctct aactcactga
    19261 catccttaaa actacgatag acactagcaa aacgtacata ggtaatctcg tccaattcag
    19321 ccaactcctc catgacgagt gaaccaatgt cctcactttg aatttcattt tcatttcgac
    19381 cacggagttt ctgttcgata cgattgacta ccatgttgat ttcatcactt gacacaggac
    19441 gtttctgggc tgagcggata atcccattaa agattttatc tctggagaat tgttcccgtg
    19501 tgccatcttt tttaacaacc actaaggttc tttcttctac tcgttcgtag gttgtaaaac
    19561 ggtgttggca ctcgtcgcac tctcgtcttc tacgaatggt gttcccttct tctgcttggc
    19621 gactatcgat aacacttgac ttggtagccc cacattttgg acaacgcatc ctttccctcc
    19681 ttatcgtttt cttttcatta taccattttt taagcgattc ccaaaacaat tcttcttttt
    19741 gcttgacaag ttttttgttt tgttgtatta tttaattaag acaaaagaat aagagaaagg
    19801 agactaagat gtcctggaca tttgacaaca aaaaacccat ctatttacag attatggaga
    19861 aaatcaagct tcagattgtt tcccatacac tggaacccaa tcaacaactt ccaaccgtga
    19921 gggagctagc tagcgaggct ggtgtcaatc ccaataccat ccaaagagcc ttatcagacc
    19981 ttgaacgaga aggatttgtc tacagcaagc gaacaactgg acgatttgtg actaaggata
    20041 aggagctaat cgctcagtca cgcaaacaat tatcagaaga agaattggaa cacttcgttt
    20101 cctccatgac ccattttggc tatgaaaaag aagaactacc aggcgtagtc agtgattata
    20161 ttaaaggagt ttaagcctat gtcattacta gcatttgaaa atgtatccaa atcatatgga
    20221 gcaacaccag cccttgaaaa tgtttctctt gacattccag ctggaaaaat tgtcggcctt
    20281 cttgggccaa acggctcagg aaaaacaacc ctgattaaac taattaatgg cctcttacaa
    20341 ccagatcaag gacgtgtcct catcaacgac atggacccaa gcccagcaac caaggccgtt
    20401 gtagcttatt tgcctgatac gacctatctc aatgagcaaa tgaaggtcaa agaagcccta
    20461 acctacttca agaccttcta taaagatttc aatcttgaac gcgctcatca tctacttgca
    20521 gacctgggca ttgatgaaaa tagtcgtctc aagaaactat caaaaggaaa caaagaaaag
    20581 gttcaactga ttttggttat gagccgtgat gctcgtctct atgttttgga cgaacccatt
    20641 ggtggggtgg atccagcagc ccgtgcttat atcctcaata ccattatcaa caactactca
    20701 ccaacttcta ccgttttgat ttctacccac ttgatttctg atatcgagcc aatcttggat
    20761 gaaattgtct tcctaaaaga cggaaaagtc gtccgtcaag gaaatgtaga tgatattcgc
    20821 tacgagtcag gtgaatccat tgaccaactc ttccgtcagg aatttaaggc ctaagcaaag
    20881 gagattattt atgttttgga atttagttcg ctacgaattt aaaaatgtta acaagtggta
    20941 tttagccctc tacgcagccg tgctagtcct ttctgccctc atcggaatac agacacaagg
    21001 ctttaaaaat ctaccttacc aagaaagtca ggctactatg ctactttttc tagccacagt
    21061 ctttggtggc ttgatgctta cacttgcgat ttcaaccatt ttcttgatta ttaaacgctt
    21121 caaaggtagt gtctacgacc gacaaggcta tctgactttg accttgccag tttctgaaca
    21181 ccatatcatc acagccaaac taatcggtgc ctttatctgg tcattgatta gcaccgctgt
    21241 attggctcta agtgctgtta ttattctggc tttaacagct ccagaatgga ttcctctttc
    21301 ttatgtgatt acatttgtag aaacacatct ccctcagatc tttcttacag gtatatcctt
    21361 cctactaaat accatttcag gaatcctctg catctacctg gctatttcca ttggacagct
    21421 tttcaatgaa taccgtacag cactcgctgt tgcagcctac attggtatcc aaatcgtcat
    21481 tggatttatt gaacttttct tcaatcttag ttctaatttc tatgtcaatt cactggtagg
    21541 actcaatgac catttctata tgggagcagg tatagccatt gttaaagaac tcatattcat
    21601 agctatcttt tatctcggaa cctactacat cttgagaaat aaggttaatt tgctttaaat
    21661 aatttttacc tagatatgta acatactcat agaacaaaag aaaccaggca aaaagtcttt
    21721 aaaattagaa aacgcatagt atcaagtgtt aaaaatcctt gatattatgc gttttttgtg
    21781 agctgactta tttcctttca ctatatcgca aaatgaaata agaacggaac gatgagattt
    21841 tggaattcaa atcaatttat aagaatgttt tagaagtaat attatcctat tccagattca
    21901 gttcactata caattgagtt ttcaagcaac ctgtttacat aatgtgtaca taattaggtt
    21961 cgtgattcca cccttttcac ctttaaaaac ctcgctttcg caaggctctt ctatttataa
    22021 gataaggcac gtttaaaggt tttccaaatc cctaaatcat ccgtttgaag aacgagacta
    22081 gcatacatgc gtccgataaa tcctgttgct accaccgcaa aaatcactgt aatagcaagt
    22141 gaaatccatg cttctgctcc ccccgcatag tcattaatcg ttcgaaacgg cataaagaag
    22201 gtcgaaataa agggaatata agaaccaatc ttcaagagga gattgtcacc agctgcacct
    22261 agagctgtca ctccaaaaaa accacccata atcaaaatca tcaaaggcga caaggctttc
    22321 cctgagtcct caggacgaga aaccatagat cctaggaagg ctgccaagac tacgtacatg
    22381 aaaagactga tcaaaataaa gagcaaggta ttcagtgaga tagcatctcc caagtgaacc
    22441 aaaataccag actgagccaa gaatggcaaa tctttaaaga gcaaaacggc agccagacca
    22501 cctacaacat agatcccaat atgcgttaaa atcactagaa acagagccat catccgcgca
    22561 tagaaatagt gacttgccct tatgctagaa aaaacgactt ccataatttt ggtgcctttt
    22621 tcactggcaa cttcctgagc tgttacaccc gcataggtaa tcagaatcat ataaagaaag
    22681 aatcctaagg cacctgctgc aattgtttga ataaactttt tattttcctt gacttcatca
    22741 atcttttctg tgaattgaat tgtctgcgct aagcgttttt cctgctcttg agacaaggaa
    22801 gcagttgaac gattaagctg attttgcagt tcattgagta tacctgtaac ctcaaattta
    22861 attccatttt caagcgatgt ttcgccatga taaactgcct ttagaacact atcttcttga
    22921 tcaatggtca aataaccttt taatttttct tctttaattg cttctttggc acttgcttca
    22981 tctttatagt cgaagttaac accatttaca ttcttcagtc cttctgctac agatggcact
    23041 gttgtcacta ctgccacttt attattttta gccatagaag aaccttggag atgcccaatt
    23101 cctacagaga ttcctaaaaa gaggaacggc gaaatcacca taaagaagaa actccatgac
    23161 tcgacatgtc gaagataggt ttccttgatt acaacccaca tatttctcat acttccactc
    23221 ctgattctag tttaaagatt tcatcgatag ttggcgcttg ttggtcaaat gttgcgatat
    23281 attgaccttg agtcaagatt gggaagagtt cccttccagc gctctcatcc tccaaaatca
    23341 atttccaact gccttgtttg gtcaagctca cctgtttgac atgaggaaga ttttccaatt
    23401 cttccttgct tcgttcactt gaaacaaaga gacgcgtttt cccgtattga ttgcggacat
    23461 cctgaactgg tccgtgcaag accacacggc catctcggat catcagaata tcgtcacaaa
    23521 gttcctcaac attggtcatg acatggtcag aaaagataat ggttgctccg cgctcttttt
    23581 cctgaaaaat gacttgtttg agcaattctg tattaactgg gtccaatcca ctaaaaggct
    23641 catccaagat aatcaggtct ggttcatgaa tcagagtaat aatgagctga atcttctgct
    23701 gatttccttt tgacagactc ttgattttat ctgtcagctt tcctttcact tccaacctct
    23761 tcatccattg agggagtttt tctttgactt ctttggcatc catgcctttt agagtcgcca
    23821 agtagcgaac ttgttcaaga actgtcaatt taggcatgag actgcgttct tcaggcagat
    23881 aaccaatccg agcataggtc tcctgacgaa tatcctgacc atccagaccg atttctccct
    23941 gatattctag gaatttcaaa atactatgga aaatcgttgt ttttccagca ccattttttc
    24001 cgactagtcc caaaatacga cctggtcgcg cttgaaagtc aataccaaac aaaacttgct
    24061 tggatccaaa acttttctct agacttctta cttctagcat ctttcacctc cgaaatttct
    24121 tgcactcatt atactccttt ttgatagcct ttacaatgtt ttttgtccat ttttagaaga
    24181 ctattgctgt gtaaaatatg gcctggagca cttttatact caatgaaaag caaagagcaa
    24241 actagaaagc tagccgtagg ctgctcaaag tacagctttg aggttgcaga taaaactgac
    24301 gaagtcagct caaaacactg ttttgaggtt gtggatagaa ctgacgaagt cagtaactat
    24361 acgtacggca aggcgaagct gacgtggttt gaagagattt tcgaagagta ttagtgataa
    24421 atccattata cagtagcaaa cttaatttat accttccgct cctcaactgt ctatttttaa
    24481 tcctgaattg ttatttgagt aactcctttt tcctcataaa gttttcttcc tctaaaactt
    24541 ctggaaaaag gcgaatagtt tcagacaaca tttttataag aaacaagttc atctgtcatt
    24601 tcaagaagga gtaatccttt atctactaat ggacggaaca gaattcaacc gcttgtccca
    24661 tatgttttct aaggattata tagtaaaatg aaataaaaac aggacaaatt gatcaggaca
    24721 gtcaaattga tttctaacaa tgttttagaa gtagatgtat actattctag tttcaatctg
    24781 ctatatctat tatgcacatc actataggat ctaatgaaaa tcacaacaga ctcattcata
    24841 gatggttacc tcagggaact aagaaaacga ctacaaagga agtcgcattc atcgaaaagt
    24901 ggattaacaa ctatcctaaa aaatgcttga actacaagtc ccccagagaa gacttctgga
    24961 tgactaactt gaacttgaaa tttagcaata attaattcac catctaacta tatttagtaa
    25021 ttatttcaga actgattaat attaaaatta actaacaatt caaaggattc atactagcca
    25081 taaattacgt ccatcagaga gagactctta ctacttttag attttagtct ttctagcttc
    25141 agaatacatc taaactttag gaaaaatgac tattcgaaag cgcgaatgcc tcaaaattat
    25201 ctcagataag ctattcgaaa cttagaatgc ttttaaattt atggaattgc gattattcga
    25261 aacctagaat gcatataacc tttagttgac agacctattc taagtctcga agggctattt
    25321 actttctatt ccttatcaaa aaagactcat tccccctttc tcctccaaaa tatggtatag
    25381 tagaaatata ctatctatga ggagtttaca tgtcacagga taaacaaatg aaagctgttt
    25441 ctccccttct gcagcgagtt atcaatatct catcgattgt cggtggggtt gggagtttga
    25501 ttttctgtat ttgggcttat caggctggga ttttacaatc caaggaaacc ctctctgcct
    25561 ttatccagca ggcaggcatc tggggtccac ctctctttat ctttttacag attttacaga
    25621 ctgtcgtccc tatcattcca ggggccttga cctcggtggc tggggtcttt atctacgggc
    25681 acatcatcgg gactatctac aactatatcg gcatcgtgat tggctgtgcc attatctttt
    25741 atctagtgcg cctatacgga gctgcctttg tccagtctgt cgtcagcaag cgcacctacg
    25801 acaagtacat cggctggcta gataagggca atcgttttga ccgcttcttt atttttatga
    25861 tgatttggcc cattagccca gctgactttc tctgtatgct ggctgccctg accaagatga
    25921 gtttcaagcg ctacatgacc atcatcattc tgaccaaacc ctttaccctc gtggtttata
    25981 cctacggtct gacctatatt attgactttt tctggcaaat gctttgacac gtaaaaaatc
    26041 cgtttggttt cccaagtgga tttttaaagc gtagattaac tatagcttga tactaaatat
    26101 actttggtat ggaaatcatg catatttttc gatagtgagg cgaggactta cctagccttt
    26161 ccgccgtgat agaaacacct gaaatctaat ggtttcaggt attcggaaac tttgagacac
    26221 taggctcaaa gtttaggtat ggaatttcga agaaagtcgc taccgtccgt aatcacttaa
    26281 ggaaaggctc aaaaatattg ttttcaacca caaaatccgt ttggtttccc aagcggattt
    26341 tgtgctttat tttgaaactt cttttgcaag aacaaagttc ccaagtgtgg cagaaccatt
    26401 tcctgcgact gctggcgtca cgatatagtc acgcacatct ggtactggta ggtaaccatt
    26461 aagaagagat gtaaatttct cacggacacg gtccagcata tgttgttgag ccatgacccc
    26521 tccaccaaag acaatcacgt ctgggcggaa agtcactgtc gcattaaccg cagcttgagc
    26581 gatatagtag gcttgaacat cccaaacagg gttgttgagt tcaatagttt ccccacgtac
    26641 acctgtacga gcttccaaac ttggaccagc tgcataacct tctagacatc ccttatggaa
    26701 aggacaaaca cccttaaact ctttttcaat atccattggg tgtctagcaa cataataatg
    26761 acccatttca gggtgaccca caccaccgat aaactcacca cgttggatga cgcctgcacc
    26821 gatacctgta ccgattgtgt agtaaaccaa gttttcgata cgaccaccag cattgttacg
    26881 ggcaaccatt tcaccgtaag cagagctgtt tacgtctgtt gtgaagtaca ttggcacgtt
    26941 tagggcgcga cgaagggcac caagcaagtc cacatttgcc cagtttggtt ttggagtcgt
    27001 cgtgataaag ccataagttt ttgagttttt gtcaatatca atcggcccaa atgaaccaac
    27061 tgcaagacca gcaaggttat cgaattttga gaagaactca atggttttat cgattgtttc
    27121 gattggagtt gttgttggaa attgtgtttt ttctacaacg ttaaagtttt catcaccgac
    27181 agcacagaca aactttgtac cgcccgcttc caagcttcca tataattttg tcatgataaa
    27241 cctcttgttt ttattttctt tattatagca tacttcgaaa gtctaaatgt ctctattttt
    27301 tagattttcc tctgtaaatc ttactatcta ataaaaacga acaaacatgt catttgttcg
    27361 ttttcacatt agagaggatt gattagattt tcacttcgat cacagcatcc cccttagcaa
    27421 ctgaacctgt tgcgactgga gctactgaag cgtagtcacc tgtatttgta acgataacca
    27481 ttgttgtatc atcaagtcca gctgcagcga ttttgtttga gtcaaatgtt ccaagaacat
    27541 cgccagcttt caccttatta ccttgagcaa cttttgcttc aaaaccgtca ccgttcatag
    27601 atacagtgtc aataccaacg tgaatcaaaa cttcagcacc atttcttgtt ttcaaaccaa
    27661 aagcgtgccc tgttggaaag gcaattgaaa cttcagcatc agctggtgca tagaccacgc
    27721 cttggcttgg tttcacagcg ataccttgtc ccatagctcc acttgagaag actgggtcat
    27781 tgacatcagc aagagcgaca acatcaccga cgataggagt tacaagtgtt tcattttgaa
    27841 gagctgctgg cgcaacttct tctttttctt cagccacttc agcttgtttt gcagctgcag
    27901 ttgcgtctac ttcatcttcg taaccaaaca tgtaagtaag agcaaaacca agggcaaatg
    27961 atacagctac cataagaagg tattgtggaa gttgtccgtt accaacataa agcattgtac
    28021 cagggatgat ggtgatacca ttaccagtac cagcaagtcc aaggatagaa gccaatccac
    28081 caccgattgc accagcaatc aatgaaagga agaatggttt acggaagcgc aagttcaccc
    28141 cgaagatagc aggctctgta atacctagga aggcagaaag agcagccggg aaagcaagtg
    28201 ttttcagttt tggatttttt gttttaacac caaccgcaac agtagcagca ccttgagctg
    28261 tcatagcagc tgtgatgata gcgttgaatg ggttagcatg gtcagcagca agtaattgca
    28321 cttcaagcaa gttgaagatg tggtgcacac ctgacacgac gatcaattgg tgaaccccac
    28381 caatcaagaa accaccaaga ccaaatggca tgctaagaat cgcttttgta gcaataagga
    28441 tgtagttttc aacaacgtgg aaaactggtc caatgacaaa gagtccaagg atagacatga
    28501 ccaaaagtgt cacgaatggt gttaccaaga ggtcaatgac atctggaaca accttgcgga
    28561 cagctttttc aaatttagct ccgacaaccc cgatgatgaa ggctggaaga acggaacctt
    28621 gcaaaccaac aacagggatg aaaccaaaaa agttcatcgc tgttacttca ccaccttgag
    28681 caactgccca agcgtttgga agtgagccag agacaagcat cataccaaga acgataccaa
    28741 cggcaggatt tccaccaaat acacggaagg ttgaccacac aaccaaacct ggcaagatga
    28801 tgaaggctgt atctgtcaag atttgtgtgt aagttgcaaa gtcacctgga agtggcattt
    28861 caagagcgtt gaaaagacca cgcacaccca tgaagagacc tgtcgctacg ataactggga
    28921 tgattggaac gaaaacatca ccaaaagtac ggatagcacg ttggaaccag ttcccttgtt
    28981 tagcaacttc tgctttcatg tcatccttag atgatgttgg taatccaagt acaacaactt
    29041 catcgtacat tttgttaact gtacctgtac caaagataat ttggtattgc cctgagttaa
    29101 agaaagcacc ttgaactttt tccaagttct caatcacttc tttattgatt ttctcttcat
    29161 ctttgaccat gacacgtaga cgagtcgcac agtgggcaac actattgaca ttttcacgtc
    29221 cgcccaaggc atcgatgact ttttttgcaa tttcctgatt gttcatttgc aaaaatctcc
    29281 ttatataaca ttttgttctt gtttgaaagc gattttattc gcccttacga ctattatttt
    29341 atcatgtttt aaaaatatgt caagcgtttt gcataaaaat attctatcca cttagtgggc
    29401 aagctttaga ttgattgttt ttgactgttt catcaggaat tccttgaaaa ataagtttga
    29461 aaccttggtt aaaaagtatt ttatttcatt atctttcaca ttttcgtaaa aatttaattg
    29521 atttcctgta tttattttat gataatcgtt tgacagtttt tcctcttttt taacataaaa
    29581 ggcttgcatt ttttatcgaa aacagttact attaaaagtg ataagatttt tggaggaatg
    29641 aatggaatgg acaactgagc gtcgttacag actttatcaa gattggacgc aagaagaaat
    29701 tcaacatata aaggaaaata tggcacaatc tccatggcat actcattacc atgttgagcc
    29761 aaaaacagga cttctcaacg acccaaatgg cttttcttac tttgatggca agtggatcct
    29821 cttttaccag aattttcctt ttggtgcagc ccacggttta aaatcttggg cacagctaga
    29881 aagtgatgat ttggttcact ttaaagaaac tggaatcaaa gttttaccag atactccatt
    29941 agatagccac ggtgcctact ctggttctgc catgcaattt ggcgataact tattcctatt
    30001 ttatacagga aatgttcgcg atgaaaactg gatccgtcac ccataccaga tcggtgcttt
    30061 gatggacaag gagggtaaga ttacaaagat tgacaagatc ttgattgacc agccagcaga
    30121 ctctactgac cacttccgcg atccacaaat ttttaacttt aaaggtcaat actatgctgt
    30181 cgtcggtgga caggacttgg agaaaaaagg tttcgttcgt ctctacaagg ctgtcaataa
    30241 cgactacaca aactggcaag cagttggcga ccttgacttt gctaacgacc gtactgccta
    30301 catgatggaa tgtcctaatc tggtctttgt agaggaacaa cctgtccttc tctactgtcc
    30361 acaaggattg gataagaaag ttctagacta cgataatatc tttccaaata tgtataagat
    30421 tggggcttcc tttgacccta aaaatgccaa aatggtagat gtgtctcaac ttcaaaacat
    30481 ggattacggt ttcgaagcct atgcaactca agccttcaac gctcctgatg ggcgtgctct
    30541 agcagttagc tggcttggtt tgccagatgt ttcttaccca tctgaccgtt ttgaccacca
    30601 aggaaccttc tctttggtca aggaactcac tatcaaagac gacaagctct accagtatcc
    30661 agtcgctgct attaaggacc ttcgtgcttc tgaagaagcc ttctcaaacc gttcccaaac
    30721 caagaacact tacgaacttg aactcaactt ggaagctaat agccagagcg agattgtctt
    30781 acttgctgat aaagaagata agggactttc aatcaacttt gaccttgtaa acggtcaagt
    30841 gacagtggat cgtagccagg ctggagaaca gtatgcccaa gaatttggga caactcgttc
    30901 ttgccctatc gagaatcagg ctactactgc tacaatcttc atcgataact ctgtctttga
    30961 aattttcatc aataaaggag aaaaagtatt ttctggtcgt gtcttcccac atgcggacca
    31021 aaatggtatc ctgatcaaat ctggaaaccc aactggaact tactatgaat tagattatgg
    31081 tcgcaaaact aactgatgtc gccaaacttg caggcgtcag tcctactacc gtttctcggg
    31141 ttatcaataa aaaaggatat ctatctgaga aaaccatcca aaaagtcaat gaagccatga
    31201 gagaattagg ctataaaccc aacaacctag ctcgtagtct gcaaggaaaa tcagctaagt
    31261 taatcggctt gattttcccc aatatttcca atgttttcta tgcagaattg attgataaat
    31321 tggaacacca actcttcaaa aatggttaca agaccatcat ctgcaacagt gaacatgatt
    31381 ctgagaagga acgcgaatac atcgaaatgt tggaagccaa tcaggtggac ggcatcattt
    31441 ctggtagtca caacctagga atcgaagact acaatcgtgt gacagcgccg attatttcct
    31501 ttgaccgaaa cctatcgcca gacatccctg tcgtctcctc tgacaactat gctggtgggg
    31561 ttcttgctgc ccaaaccttg gtcaagacag gtgcccagtc tatcatcatg attacaggga
    31621 atgacaattc taattcgcca accggactgc gccacgctgg ttttgcatcc gtactcccaa
    31681 aagctcctat tatcaatgtt tccagtgact tttctcccgt cagaaaagaa atggaaatca
    31741 agaatatctt gacccgggaa aaaccagatg ccatttttac ttcggatgat ttgacagcta
    31801 ttctggtcat taaaatcgct caagaattgg gcatttctgt cccaaaagag ctcaaggtca
    31861 tcggctatga tgggacctac tttatcgaaa attactaccc tcaattggct actatcaagc
    31921 aacctttgga agagattgct tgtctcacta ttgatcttct cttgcaaaag attgaaggca
    31981 aggaagtcgc cacaactggt tacttcttac cagttacact attaccagga aaaagtattt
    32041 aaacacaaga aaactcagac cgattcgtct gagtttttta tgatcttaaa ttttcgagat
    32101 agcgctgggc tgtctctagg ttaaaggttt tatctgcgat aagctgctcg actaggggag
    32161 caacttcaga ttcactagcc ccagctagga gagctaggga tttggcctgt agtttcatgt
    32221 ggccttgctg gatgcccgta cttaccaagg ctttgagggc tgcaaaattt tgagcaagac
    32281 cgatggacac gataatctgg gctaattctc tggcagaagg atttcctagt agatcatgac
    32341 tgagagctac acgtgggttg aggccgatag agccaccctt agtcgctaca ggcatgggca
    32401 gggtcatctc accgaccaat tcttctcttt caaggtccag cgtccagcag ctaagacctt
    32461 gatagcgtcc atctcgactg gcaaaggcat gggccccagc ttcgatggca cgccagtcat
    32521 taccagtggc aatcaaaatc gcatcaatac cattaaaaat tcctttatta tgagtagcag
    32581 ctcggtaagg atcagcctgc gcaaactgac tagccaatgc aattttctcc gcaatctctc
    32641 gtccttgatc cttttggcgg ctcaagtagc gaaaggccat gcgacagctt gcagtcacca
    32701 gagaatcggt cgcgtagttg gacaggattc ccatgagact ctgtccctga ctgagttctt
    32761 ctaagactgg tttcaaggct tccagcatgg tgttgagcat attggcaccc atggcttcct
    32821 gggtatcaac atgaatataa acaacgagaa agtctggttc accttttatc tgctcgacat
    32881 gcaggtcact cgccccaccc ccacgtttaa cgatagaagg ataggcttga ttggcaagct
    32941 ccaagagctc cgctttcttg ctggcaatct tctcttgcgc tagtttagga ttagcaactt
    33001 gataaagggc tacctgccca atcatctggc gctgatggac ttgtgcagta aaaccacctg
    33061 cacgcttgat gattttgctg gcatagctgg ccgccgcaac cacagagggt tcttctgtca
    33121 catagggaac ggtgtattcc tgaccgttga caagtacctc cggaaccagc gaataaggca
    33181 gagaaaaagt tcccaccaca ttctcactca gctggtctgc cacagtcaca ctcatctgtt
    33241 catccttctc cagactagct tgtctctcag gactaaggag cgcctgagct tttagcagct
    33301 cgaggcgctc ttggtatgat tttttagaaa atccattcca acttatcttc attatttttc
    33361 aaccttgcta taacggcgtt ggtggtcaag aatttcaacc aaggcaaaat cttgattttc
    33421 atagccagca aactgggcag agtttgtttc atccaagttt acttcctcaa aaaagacctt
    33481 ttcatagtct gcaacggata gggcagttcg ttggttgagc ttgttcaaac ggtctttatc
    33541 caaataagct tcatatcctt caaccaattc accactgaag aactcagcca cagctccact
    33601 tccgtaacta taaagggcga ttttatcccc agctttcaag ctatctgtat tttccaagag
    33661 agacaaaagt ccaaggaaaa gtgaacctgt gtagatattc cccacctttt gactgtagag
    33721 aatagactgg tcaaaatgct tttgtaagag gtcttttttc tcttgaggca ggctcttatc
    33781 catgattttt ttcaagcctt ttagcgctaa tttaggataa ggcaagtgga aacaaacagc
    33841 cgcaaaatca tccagagtaa gctggtagcg tttttgatat tcaagccaag tcgttttcaa
    33901 actatccaag tattgttggg tagaataaac accatttaca taaggagttg tcgagtaatt
    33961 tggtcgccag aaatccatga tgtcacgggt ctgagctaca ttgtcattat taaaggccat
    34021 catgcgtgga ttttgtgtaa tcaacatagc tacacttcca gcaccttgag ttggttctcc
    34081 tggagtttca ataccgtatt tggcaatatc actggcaatg accaagacct tggactccgg
    34141 agaattttcc acatgcaatt tggcataatg aagggcagca gtcgctccat aacaggcttc
    34201 tttaatctcg aaactacgag caaagggctg gatgcccagc aagccatgca caaagacggc
    34261 cgcagcctta ctctggtcaa ttcctgactc ggtagccaca atgaccatgt caacttcttg
    34321 tctttcttgc tcagttaaaa tagagtcact agcactggcc gccaaggtca caatgtcctc
    34381 agttaggggc gcaatactca attccttgag taagagtcct ttacttaatt tttcagggtc
    34441 aattcccctc gcttctgcta agtcttgtaa tttcaagaca tattgactgg tcgcaaaacc
    34501 aatcttatca ataccgattg tcatatttac ctctgtttta tcattcatgt aaaaaatcgt
    34561 tctatactat tttatcacaa atggcagtaa aagagagaaa aaagacttga ttcaccaaat
    34621 caagcctctt attggtcatc attttaaaga atgattagtt gctagagagt tcaccgatat
    34681 aagtagcttt ataagctcca ttcacagtta tcagctcctg gaggatcaaa tttcctgagt
    34741 aagtccttcc catctcatct acaaattttt gataaaactg actggtcgga atttctctga
    34801 catccttatc aaatgtctta tcaagtgttt tactaacctt ctcagcaatc aattgatgct
    34861 cttgccatcc actttgaaac tctgagcccg aactagaaac catgactggg ataaacaaca
    34921 aggtcagtag atttacagac aataaggaaa gta
//
LOCUS       DAVAGB010000016        34775 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVAGB010000016 DAVAGB010000000
VERSION     DAVAGB010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34775
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.016"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(<1..2353)
                     /locus_tag="VQO19_000910"
     CDS             complement(<1..2353)
                     /locus_tag="VQO19_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HET1349198.1"
                     /translation="MDALTRRQFDRAMFAKERTLAIRVGEYASRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQVIGMSCFFNREGKMEIRDLTESNITINADSYFLHGL
                     TKSEIEYQIAGITCKTDKKSLTVGMKTGRSLELDNVFMTQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFTFKGGLRGRISADSKAGNDTQYS
                     YEGTITKQIKQQDGIEAKIQAQIEAADAAFDAEFDKREKAITDAIELAKARAEEVKRE
                     LSDTINQRFNSFDNGPLKETKRKAEEALRNAGASTLLAQEAKRIGLDSVARLEAFKSQ
                     TTSAQTALSGDLDALKRTIANDIRPKQAQAEAEIAKQAEALSRTKNELAGASTLIAQE
                     AKRIGLDSVARLEAFKLQTTSAQTALSGDLDALKRTIANDIRPKQAQAEAEIAKQVEV
                     LSRTKNELAGVKSAQATYEETTTRRLSELTNLANGKASKSELTQTAEELSSKIASVQV
                     GGRNYIRGTKRMMLARGLWASGTFRPSGAGTAKTIDVLDSPATGFDKAIRLTSSNARD
                     QIGIAQDGFYISQGTYTMSCWVKGRRGQKVKLQTYWQVNDNSGISPIFTLKDENWTKL
                     SFTSARNRAGVASIGYVYLVNAEVGEYLDVLAPQLEDGSLATSS"
     gene            complement(2358..2708)
                     /locus_tag="VQO19_000911"
     CDS             complement(2358..2708)
                     /locus_tag="VQO19_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349199.1"
                     /translation="MAQLTINGVAVKPPKYFQVGIQDIDGETGRNANGDMVRDRITTK
                     RKLDCEWGMMTQGEISQLLHAVSSKFFEVSYPDPMDGQVTKTFYVGDRTAPSYTFTEK
                     FKPWSGAKFNLVER"
     gene            complement(2717..6370)
                     /locus_tag="VQO19_000912"
     CDS             complement(2717..6370)
                     /locus_tag="VQO19_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349200.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDQVKNATAKVR
                     EQSNSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIKSTEAFKRFSNGQSWDQLDFQTQQQ
                     IRLMAILEQATAKYGDTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSF
                     AMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGGAGDLADAVDDAG
                     DSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKG
                     GGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDAAFRPEGIKRIKT
                     ALDQIAKTMGEIATDPRVVNAFNRMAEKIAYALGQVTGSITTIGLGIGVFLAESIANG
                     LGRQKERITRALVALFDNVGNLSEAVGNIAQDFSSAFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKGFEKVVVTSAPKISSVFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVVPAINSIANAFNGLIDIIQILWENSWQPFAEFLSGVFGVSIEGISDL
                     LGGGLLATLGLLADAIKLVADGFTVFSDWCKENKEPIVALITTWQTINFLSWAEQAGG
                     LAGAFSLLGSKVSLIVGGIKNLGLAIKALTFDKLVSFGETIYLNTLYAKDFVVNSGKT
                     IAQLGKTALELGKSALAWTAHAAKMGLATAAEFAHSVAAGVATAATWAFNAALAVLTS
                     PITWIIAAIAALIAIGVLLYQNWDTVVEFAKTAWQGLCDFISGICQAIGEFFSGLWTK
                     LQEIFEPIGQWFGEKFQQAWDAIVNIFSGIGEWFSGVFQGAWDAIVNIFTPIGSWFGQ
                     RWADVTSALANIGAWFTDMFQKAWTGLTNIFSKLGSWFGERWNDVTSALSKVASWFGD
                     IFGKAFDAVKNAFSSIGDFFKGVWDTVKSIFVNAGQMVGEAVGGAFKSAVNAVLGTIE
                     NVVNGFIGMINGVLGVVRNLPGLGWVGSVSTVSLPRLARGGIVDSPTIAMIGEAGKEA
                     VVPLENTGFIQTLGRVVSSAVVNAMAGVSPQGGFSGDGDIVIQIAGHEFGRVAIQEIN
                     KEHERAGQTLLKI"
     gene            complement(6357..6707)
                     /locus_tag="VQO19_000913"
     CDS             complement(6357..6707)
                     /locus_tag="VQO19_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349201.1"
                     /translation="MFLDIGGKPLDFWDLTVLEIREMIESYNRVKIQERKEKIIDSYR
                     LSQMISNHVSLLLSKDAKAFEFWEYAPELFVEEQQAVEQERQRQALLLHKERMRDFAE
                     RHNRKRKEEINGNS"
     gene            complement(6746..7126)
                     /locus_tag="VQO19_000914"
     CDS             complement(6746..7126)
                     /locus_tag="VQO19_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349202.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSLEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKDKKTSKKKMTVVK"
     gene            complement(7131..7544)
                     /locus_tag="VQO19_000915"
     CDS             complement(7131..7544)
                     /locus_tag="VQO19_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET1349203.1"
                     /translation="MLANGITLSYGEAKGTYTKLVGLKEVPEFGIELEKVENTTLEDT
                     VKKYEFGIGDIGELEYKFSYNNSSATAPYRVLRKAADDKKKLYFEQAYPDGTKVNFEG
                     QVSVKLGGGGVNAVIEFTLKIALQSELEFTDGVGG"
     gene            complement(7547..7915)
                     /locus_tag="VQO19_000916"
     CDS             complement(7547..7915)
                     /locus_tag="VQO19_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349204.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDQEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGVVDLDSELVFQFRMEN"
     gene            complement(7912..8427)
                     /locus_tag="VQO19_000917"
     CDS             complement(7912..8427)
                     /locus_tag="VQO19_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HET1349205.1"
                     /translation="MSELLGADRLIAKCRRLASKKTGEDIVLRAVHNATIKVVQADAR
                     RLAPARDGELITSIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPKGQASHSGISPEV
                     SVTYKSSPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIK"
     gene            complement(8402..8740)
                     /locus_tag="VQO19_000918"
     CDS             complement(8402..8740)
                     /locus_tag="VQO19_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349206.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYAKEAETVRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHKVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            complement(8721..9032)
                     /locus_tag="VQO19_000919"
     CDS             complement(8721..9032)
                     /locus_tag="VQO19_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HET1349207.1"
                     /translation="MSIELLKKLTGEEDTQLLMLLQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGERSRTEGGIAVVYGEKGLSTGLLQRIRMHRLARVAGHVFEA
                     E"
     gene            complement(9034..9222)
                     /locus_tag="VQO19_000920"
     CDS             complement(9034..9222)
                     /locus_tag="VQO19_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349208.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGGELEITEERYVELADNIASNGVA
                     ISDVLEKILPEPEFLEED"
     gene            complement(9212..9394)
                     /locus_tag="VQO19_000921"
     CDS             complement(9212..9394)
                     /locus_tag="VQO19_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HET1349209.1"
                     /translation="MSLLLRRHYIQEEQVSQYSDLENKTLEELKNLAKEAGIAGAYKL
                     SKAEIVEVLEDLKSEV"
     gene            complement(9399..10244)
                     /locus_tag="VQO19_000922"
     CDS             complement(9399..10244)
                     /locus_tag="VQO19_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000123892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N4-gp56 family major capsid protein"
                     /protein_id="HET1349210.1"
                     /translation="MTAGQTKLATMVNPEVMADMVSAKLPKLIKFTPLAYVETALQGQ
                     PGNTLTVPAWEYAGDATEVGEGQAISPDQLTTKKTTMTIKKAAKGYEITDEALLSGLG
                     DPLGQATYQLGLAIANKIDDDLVAVAKTATQHITETPTTLAAIDKALEIFEDEEDAQY
                     VAIINPKDAIKLKTDVAKEWTKGSELGADMVVSGTFGEVAGVQIVRSKKVDEGKGFIV
                     KVSPSQTQTDDANKYGAFVIMLKRDVAIETDRDILKKTTVITGDEHYGVYLYDPTRVV
                     KFGEG"
     gene            complement(10250..10819)
                     /locus_tag="VQO19_000923"
     CDS             complement(10250..10819)
                     /locus_tag="VQO19_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001001559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HET1349211.1"
                     /translation="MNEETQTVETVEEQKVPAEPAQQPQDEKKYTDADVDAIIDKKFA
                     KWKSEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAKAMLSE
                     RDLPVELVNVVDLTNAETVSQSVAVLQKSWEQAVQKGVQEKLKGGAPMKQAPVDSDGI
                     TKEEFARMGYQSRNELYQKNPELYKKLKG"
     gene            complement(11022..11273)
                     /locus_tag="VQO19_000924"
     CDS             complement(11022..11273)
                     /locus_tag="VQO19_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349212.1"
                     /translation="MLKKAKQLASQEFSRLAGREIKEEDCFVVWFSKTLQNWKALVST
                     NAITSSEPCGDYAEITHNGDKNETYVDVYAKVSNRAIKD"
     gene            complement(11275..11520)
                     /locus_tag="VQO19_000925"
     CDS             complement(11275..11520)
                     /locus_tag="VQO19_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349213.1"
                     /translation="MKYRKKPVVVEAVQWNGNNHKEVIDFAENKIWFDALGNIWIATL
                     EGDMVAKKGDYIIKGVQGEYYPCKPDIFAETYEKTEE"
     gene            complement(11563..11976)
                     /locus_tag="VQO19_000926"
     CDS             complement(11563..11976)
                     /locus_tag="VQO19_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET1349214.1"
                     /translation="MIDIALAIAKKAHAGQVDKAGVDYIQHPLYVASQVNTEQEKAVA
                     LLHDVIEDSDITAADLFASGLSNEVVTAVQILTKKKGQSYQEYLGKVKSNNLARVVKL
                     ADLKHNSDLSRLKSVTNTDYERVKKYKNAIYYLST"
     gene            complement(11973..12182)
                     /locus_tag="VQO19_000927"
     CDS             complement(11973..12182)
                     /locus_tag="VQO19_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349215.1"
                     /translation="MKDIKYYRTTTNNAQVLRLIDGVMQVFDIEKKWVNSMDWFNKIF
                     FNDFTDFEEISENDAFTYIDRMVAA"
     gene            complement(12184..13821)
                     /locus_tag="VQO19_000928"
     CDS             complement(12184..13821)
                     /locus_tag="VQO19_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HET1349216.1"
                     /translation="MKNQEYWAKRKANLIYQQMDKAEKQADQFDKVYQEAKTYLDKEV
                     NKIFDKFQRDYGLSQVEARQVLKNMKDKKNLNELRKVLEARPNDPNIQRLLADLDSPA
                     YSFRMKRLERLSDDLDRMRESIYHSEKTGSDAFYSDLMKDSYYKATFDLQQQTGLAYG
                     FSGLPENEIKHLQSFSWVGDGSTYSTDIWKNTGKLTSSIKDELLMSLMTGRDTRETAQ
                     AIAERFNVGQNDARRLVRTESAFFHNQMELLSYEEADIEKYIFVAVLDKRTSRICQEH
                     DNQVYDRDKAVPGVNCPPMHPWCRSTTVGYDEDADYSKLKRRARNPETGKVEYVPADM
                     TYKEWYSKYVAKDGEKVYNQDTREAKAKFYSEQLLSKISGVEPKITSDMQRIAGENKL
                     AGLEFRKKTVESLSRKIIADSLVENISLSKAVSKINDALRYTTIFDSDTFTEEYLKMK
                     QKLIAEGYKIVKVKNTWLVDGPYKGVNTVVEKDGINFEMQYHTQESFDLKNGSLHELY
                     EKYRDTNTSDLERMKLFKEMLDLSNGLEIPKNIERVK"
     gene            complement(13730..15199)
                     /locus_tag="VQO19_000929"
     CDS             complement(13730..15199)
                     /locus_tag="VQO19_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HET1349217.1"
                     /translation="MYQYLTYPRDGYDEGSLKKDLIYKLITIHSTEGSHLKKLKSYYL
                     GEHAILEHTRRNVNAPNYKTVANHAKDIADTATGYFMGNPIKYNNTADGDIDELLTAF
                     DGAEIDQVDAQNALNMAIYGRAYEYIYAKEGMAELDSTSIDPENTFMVYDDSIERKPL
                     FAVYYYEVKDDTKDTTKHQAEVFTENLHYHMVLRSTDSGTTQSEEATPHNLGQIPIIE
                     YRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAM
                     KILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYTFSHVPNLTDENFAGN
                     TSGVAMEFKLMGLEMITKTKEANYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRG
                     LPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEEEKKKNMEDMPMFNQE
                     NTKPEDEVEDEESGVLGEEESQSDLPADGQGRKAGRPVR"
     gene            complement(15211..16509)
                     /locus_tag="VQO19_000930"
     CDS             complement(15211..16509)
                     /locus_tag="VQO19_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HET1349218.1"
                     /translation="MSQTYQIKQSDIVIDLPKTVGAGYGQFWRSRSLYRVVKGSRGSK
                     KSKTTALNYVIRLLKYPWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITIKATGQKILFRGLDDELKITSITVDVGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWLKRVFFDEETRRADTFATTTTYKCNEWLDGVDIK
                     RYEDLYHTNPRRARIVCDGEWGVAEGLIYENVTVKDFDKDELLRDSANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIIADSAESRL
                     IEELRSEHGISRIKESRKGKDSIMAGVSKLQGYAIYVHPDCKNIMDEFYSYCYQRDKE
                     GNWLNKPEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
     gene            complement(16487..16927)
                     /locus_tag="VQO19_000931"
     CDS             complement(16487..16927)
                     /locus_tag="VQO19_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HET1349219.1"
                     /translation="MSGLRIKQKRFADEYIISGNATEAYKKAGYRVSSDRVAGVEGHK
                     LLKNPKIKSYIDERLKQLDSEKIADQQEVLSYLTSVMRGETQEQTLISIGELGQTITD
                     IDVGAKDRIKAAELLGKRHRLWTDKVEADVSGTVVFANESDIPD"
     gene            complement(17216..17298)
                     /locus_tag="VQO19_000932"
     tRNA            complement(17216..17298)
                     /locus_tag="VQO19_000932"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17265..17267),aa:Tyr,seq:gta)
     gene            complement(17379..17783)
                     /locus_tag="VQO19_000933"
     CDS             complement(17379..17783)
                     /locus_tag="VQO19_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HET1349220.1"
                     /translation="MNKAKELLKELQDLDMDIQSRIDEINELEAGLLSSPKWTDVKVQ
                     GGQTRKVDDVYTQLVVMKEAIEQDTKEVINRKLELGRMINRLKNPKYRAVLRMTYINK
                     GTADSVCYDLNMSRTTYYRLKNEAVLALEEVI"
     gene            complement(17854..18225)
                     /locus_tag="VQO19_000934"
     CDS             complement(17854..18225)
                     /locus_tag="VQO19_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349221.1"
                     /translation="MRPCKYPYSGRRKKQETPSPIFSARPIFKEVPIVEEVKVEFEVE
                     ASTGRIYPETIIHLDISGYGNRVHSVHRFPGVFLTVGESIQLKILFYKRLRNFTADRF
                     LTFRESDWKFFIRDLVNEFVR"
     gene            complement(18222..18434)
                     /locus_tag="VQO19_000935"
     CDS             complement(18222..18434)
                     /locus_tag="VQO19_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000160160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349222.1"
                     /translation="MTKFVKIQSCYRGHTEDELINIDDIGRICLGPNILFLRTPYNLG
                     EHHISITQNSVDKLLKVLDIIGEDGK"
     gene            complement(18435..18935)
                     /locus_tag="VQO19_000936"
     CDS             complement(18435..18935)
                     /locus_tag="VQO19_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HET1349223.1"
                     /translation="MNIKALIKKYEELWNEHSPFYEPVPYTSMVELFLKELKQLDEPQ
                     KVKIPQFVAEYIEFKKKNNFHVYGAMRVIEDHYDKKVPDWFYENNIEKFCLAWLDGYE
                     VEEEKRYLVTLKNRQPLVKSQSGSTLYFSQDITARNYKGTQKELEEAKFGWVFDCEGI
                     DIEEVE"
     gene            complement(18937..19251)
                     /locus_tag="VQO19_000937"
     CDS             complement(18937..19251)
                     /locus_tag="VQO19_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349224.1"
                     /translation="MEELKKKVNAVYNWTVEDGKPQPPKQNLPQAVKDRADYFWEMAE
                     DGMTFMGAMECIFADEKPTDYDLGSTKDWLPKSKEFDDWVGYSPSMARVIIAVYLIYR
                     GN"
     gene            complement(19402..19740)
                     /locus_tag="VQO19_000938"
     CDS             complement(19402..19740)
                     /locus_tag="VQO19_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349225.1"
                     /translation="MSYDLEILAKIESGDYICIAEPRYSSPTYNFGKMFRVAMDWDFD
                     QGTIYNVADIFENIKRGITELERQPEKYVQYEPANKWGTINDALYVLRSLRDCILEQD
                     IDTKYLYVRW"
     gene            complement(19740..19892)
                     /locus_tag="VQO19_000939"
     CDS             complement(19740..19892)
                     /locus_tag="VQO19_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349226.1"
                     /translation="MSYTVTLYFDNMVDETHFFKKEGDAAKCKAQLESKYRGDRMYKV
                     KMEEME"
     gene            complement(20186..21529)
                     /locus_tag="VQO19_000940"
     CDS             complement(20186..21529)
                     /locus_tag="VQO19_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET1349227.1"
                     /translation="MIGNVVSIDSQPKMITTAKGDIKANSPSNVLMSFKADDQLSIYL
                     KHNDFSQEHELLKDIKIGNTLFKKGELPSNFDSVVKVYFESVLGVAFSNQAMLDGMET
                     FFSERSYNPVIEYMERAAEKWDGRNRIDRMLQVYLGAEDIPLVSKIAQMWLVGAVAKV
                     YDPYVKFDYVLDLVGGQGVGKTSLLQKLGGEWYTDAVTDFSNKDNYDIMLKSLIVNDD
                     EMVASNRMSFAETKAFISKTSLRYRKPYMKRTEEFAKNFIIARTTNQTEYLKDKTGER
                     RFLPIMADSRQQKKHPMEIDPDTIEQIWGEAVTIYRAGANLMFDENTEDELNIYREQF
                     MYRDEVELQVLEYLDMPVPENWQNWSIQQQHQYTSKYFDNSSDFDPGSKKLDKVSTRE
                     MMYNLFMRNSNDRKLSTKINMIMDNHPDWKKSVFRAGGKSTKGFVRVKNSEKTNR"
     gene            complement(21532..22353)
                     /locus_tag="VQO19_000941"
     CDS             complement(21532..22353)
                     /locus_tag="VQO19_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HET1349228.1"
                     /translation="MPSMKEYALQYQKLGFSVIPINPKNKMPLIDFADKPAMTPSEIE
                     NFWDGYPNANIALKTTNFFVIDIDKHGKSNGFESLKKWKHLNLIEPTLQAKTASGGKH
                     LFYFKREDEPITQMIGFLPGVDIKAHENNYVLVAPSATDKGQYEWDLEKSKEGGTMVT
                     PSKDLIQSIKKQYGETHGYKYDGKDGLRDLVRRSHTRDRTQTTDLFETIALGFGDEGG
                     RNDKLAKFVGGLLYRAVDDGVVVQLARLANANSPNPLPEKEMMRTIESMIKKDRR"
     gene            complement(22526..23029)
                     /locus_tag="VQO19_000942"
     CDS             complement(22526..23029)
                     /locus_tag="VQO19_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349229.1"
                     /translation="MSLLDIAKSIKKEGFDPRKDSANGPAPIPAGTYPVVLKKATFNV
                     SDKGWESLGYQFEIRGGDYSGRSEFATFGTLTEWNGKDLNWAVERTMKFFIKALVLAG
                     DSMQGNEEDGKALEEALQRKAVGSYYNLVISVTKGKDGREFRNYDLEEEAQPLTEADI
                     DEDDLPF"
     gene            complement(23049..23825)
                     /locus_tag="VQO19_000943"
     CDS             complement(23049..23825)
                     /locus_tag="VQO19_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET1349230.1"
                     /translation="MAFTLPANKPQVPKDTPRNFFIYGETMSGKSYLANEFPNPIVLN
                     TDGNAEANTVPSIQLINEKDDKGRITNSVIKQLGDILLALQTQKHSYETVVIDVIDDV
                     IEMIKIAVCDELTPVGKPRLKSLSEIPYGKGYDFFNQAITELVIDLKALPMNVIYISR
                     QVSEYDDNGNATKDKPSLKDKYVNLINGNSDLMIHTEKLGNNYNREVDRKRKTYYVNH
                     VDDKAILKILATIRGAVEPAKTEKTKEAPKKEVASDDELF"
     gene            complement(23825..24142)
                     /locus_tag="VQO19_000944"
     CDS             complement(23825..24142)
                     /locus_tag="VQO19_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349231.1"
                     /translation="MNKTTEMIVFRSRKTGEFLNSYKDRSSLAFAADFCSLEYCLKLP
                     RKKYEDNKKTYKALAAAFDCEIVAVEAEYKLTYPNGSEVEPIKRDRSSIEDMIKDIIG
                     GVL"
     gene            complement(24161..25354)
                     /locus_tag="VQO19_000945"
     CDS             complement(24161..25354)
                     /locus_tag="VQO19_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III restriction endonuclease subunit R"
                     /protein_id="HET1349232.1"
                     /translation="MSITITLRKWQAEAIKRSEHLSNGIFLEALGGRGKTICALAIAK
                     HKKAKKIIITNNRLAILNGWIDAVKFMNFDKGVEIIIQTDRYLQNQVKKGHKLDCDVL
                     IVDEWQNMSSDKQVALYRKIKRKYTIGLSATPIRKKGQNFYPLEKTVFGWATPNNKFD
                     WQKTHGKMVYDPFSYSKEKWEDFQNYESYISSLPNFFRWEEIEGIENAVENNGFEIKF
                     YQKRVASGNPEKLAEFRKLNLVTVDGKTAMAKQSFGRKTFERYLNQTGVAVDFPKLKP
                     VNADTPLMLQLDGLIERAPHDMLIVSKSKQIVNVISERHPEIGIWTGDIQEGLYKKFV
                     VATSQVLGVGVDGLQHKYQTIVVLDPVEEGSGEYDDYRQLLWRITGSRQQHDVNVIEF
                     YYKES"
     gene            complement(25317..25802)
                     /locus_tag="VQO19_000946"
     CDS             complement(25317..25802)
                     /locus_tag="VQO19_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000696057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349233.1"
                     /translation="MKILAIDPSSNKIETSTTGVVLLDNARLVDSWVVSYGMRGFADW
                     FHEIGTNLEFDVVIVEEFKARDNDKSKDNSVAETIAYIQLCYPGAILQFNAGYKSDIP
                     NDLLKILDLWKFEKSHHQDIRAAARLGLFWAMRNDIEEVVHDIGKVVSEYHNNAKKVA
                     S"
     gene            complement(25802..26161)
                     /locus_tag="VQO19_000947"
     CDS             complement(25802..26161)
                     /locus_tag="VQO19_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349234.1"
                     /translation="MELMNKTRVTDSLAVVIGPESIEVLVTEGFLFDVAIRFVKVDET
                     NLDQGNEKPVFTPEYKLVTVAKYKEKPIFESEEDIRKFEKQAKEVKSLFAFAKVNKQN
                     WFNTALYPGVLTEKVGV"
     gene            complement(26161..26643)
                     /locus_tag="VQO19_000948"
     CDS             complement(26161..26643)
                     /locus_tag="VQO19_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HET1349235.1"
                     /translation="MASLYELTGQFLTIYQMDIDDETKTDTLEAIDWQEQFEQKAEGY
                     AHVIKNLEADVAMYKAEEESFKAKKQVAQKKLDYVKDNIMAAMNVTGQTEVKSGALII
                     KIAKNPESVKVNEDDLPKKYFTKKVTLAPDKKTLKELLKSGKKVKGAELVRTEKLVIK
                     "
     gene            complement(26636..27358)
                     /locus_tag="VQO19_000949"
     CDS             complement(26636..27358)
                     /locus_tag="VQO19_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HET1349236.1"
                     /translation="MHEICPGRLTPEVTRLLNEKFGTTYTKTQIGEVRRRLGLPVGKV
                     YQGKLLTKEQHDYLVSIQKNKISRDVANEMNLKFGLSLTEKQIKSYRRNNNLHSGLTG
                     RFEKGQTPHNKGKKYPNMPKNGGQFKKGNRPPNYVPVGTINYTTDGYPKEKIGEPNQW
                     VLKHRKVWEEHHGPIPKGHSIVFLDGDKTNYDILNLACLSKNEIARMNQNHLFTSNAD
                     LTKSGIGLTKLTNKIREVEKNG"
     gene            complement(27372..27602)
                     /locus_tag="VQO19_000950"
     CDS             complement(27372..27602)
                     /locus_tag="VQO19_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349237.1"
                     /translation="MVRNKLTDLTNTLFAQLETLDDRDLTADELKTELQRSKQMVAIS
                     SQILQAGQLALDAKKFKDKAGEDNAPIALLEG"
     gene            complement(27603..27944)
                     /locus_tag="VQO19_000951"
     CDS             complement(27603..27944)
                     /locus_tag="VQO19_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349238.1"
                     /translation="MTQAERIREYYREHPAASYDEVAEVVGTTNSNVRANLAKDIKAG
                     RCVRLEDKSYDYSPYYNHTQALTELVDWKNDIRREWVDMLTRAAEKETDSNVMRLLIK
                     EANKLMKEVTK"
     gene            complement(27956..28147)
                     /locus_tag="VQO19_000952"
     CDS             complement(27956..28147)
                     /locus_tag="VQO19_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349239.1"
                     /translation="MMEYIYLVIIVGIGLWSLVNKLDDHAEMKQKERQLMANNVARMN
                     LRNSDKQFTYDVEPPEGLK"
     gene            complement(28144..28338)
                     /locus_tag="VQO19_000953"
     CDS             complement(28144..28338)
                     /locus_tag="VQO19_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349240.1"
                     /translation="MNLLSRIKNYFSEEVKETNLDWKEVALDLNQSLIETQEKLQEAN
                     QEIADLKKIVAIYKEKEKEK"
     gene            complement(28335..28607)
                     /locus_tag="VQO19_000954"
     CDS             complement(28335..28607)
                     /locus_tag="VQO19_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349241.1"
                     /translation="METVQIVRIKDVIIEKVSANDEELKRIFGCSKRQAGERRREMQK
                     LPSQQKHLLDSGQLVTIKGFYEYLQYRGTKAWKKEMETSKKMRSAG"
     gene            complement(28850..29386)
                     /locus_tag="VQO19_000955"
     CDS             complement(28850..29386)
                     /locus_tag="VQO19_000955"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349242.1"
                     /translation="MESVLESLKQEKDHLEKIIKVVTSGGKFLRLPYQKKSRSISENL
                     KLISQNLDRLSCLYNQRGERMTDRELFKLPEDYVESTGLDKITFEVPFELFTKILKGY
                     GHKLAWEDFRQIKIHPSTRTKKTVGQCQFLFSIWMNDHLKPAIKPSKELQKEPVRKTK
                     KQKRLHKLAQNLLHRMKG"
     gene            complement(29418..29633)
                     /locus_tag="VQO19_000956"
     CDS             complement(29418..29633)
                     /locus_tag="VQO19_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001198773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET1349243.1"
                     /translation="MQWTLEAMRINKGLTQAELAEKFEVSSQTIARLEKDSSDIGYQL
                     LKKYMFFFNVKFDDIFLGKKYENFVND"
     gene            complement(29646..29831)
                     /locus_tag="VQO19_000957"
     CDS             complement(29646..29831)
                     /locus_tag="VQO19_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET1349244.1"
                     /translation="MWEQLNRIMQERNLNGYQLSKMSGVNRSFFSDLKSGKVKYLSWT
                     NICKIADALEVSLDEFR"
     gene            29979..30170
                     /locus_tag="VQO19_000958"
     CDS             29979..30170
                     /locus_tag="VQO19_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349245.1"
                     /translation="MKSFKYFRESLTAEDMQAISAKANEATKQIDHTDGLQLGKVSGL
                     TSVITTIELLEKYHEWLHS"
     gene            30387..31076
                     /locus_tag="VQO19_000959"
     CDS             30387..31076
                     /locus_tag="VQO19_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HET1349246.1"
                     /translation="MIFQVKVNSSVSRPVTVEDICPNCKKPTNPDLVNSSYFSLGENK
                     TSLVLTCRCLGCKHFWTEEFIATRFLINDYTEKYEIEHIKVIPNLPSDIPISDDVEIV
                     SPIGKQIYVQALKAEHEQLDHIAGIGYRKALEFFVKDFSIVTNPDDEDKIIKMSLKQV
                     IEKYIKDEDLKTFALASAYIGNDEGHYYRNNPDKGFTDLKNYLHGVIHYMEMKLNFLD
                     AQELVNRSKKS"
     gene            31338..32105
                     /locus_tag="VQO19_000960"
     CDS             31338..32105
                     /locus_tag="VQO19_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001023158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET1349247.1"
                     /translation="MQIIAENITHFRKQRGITQKELAKEVGITASTMTDYMKLRSAPS
                     FGVIQKLADYFGVKKSDIDTTFKEESTNSLPDAPDSLTQQIMDKVVQLITPNKKIVLR
                     TSEELLESQKNEEETKVNEVSENIIRLDDYRQTTYRRVTGVVSAGSGSIQDDDLDMEV
                     SFYEDEIPDDYDAIAYVVGNSMEPKIKNGDYLFIKNTQQVDYNTIGIFQVDGANYVKK
                     LRQGYLESLNPDYEDIHLDESNDIRTIGKVVSVYREK"
     gene            32127..33197
                     /locus_tag="VQO19_000961"
     CDS             32127..33197
                     /locus_tag="VQO19_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349248.1"
                     /translation="MELKEIIENIKKEIPVLDSSTDYWLVRANSGEYYTDFNLNGYIG
                     IGWNEITLEDIRRADNNSNVLKEILKEKLTFQDDSEPSENKYGITAGQLLRFVNNIKR
                     NDIVVVPSEGSERFLVGKVTGPLYELNQSQLEEYKSEELTHNRSDFAKRWKVYWLGWF
                     NRSDADSALYKMIYSHATLSNINDYKPFINRALFPCYIEDEKLYISYHVTEEKDIQGV
                     YLGQFVYQYSLLTRLLFPETRVDSKINVQSEGIIELITHTVNYGLIISAILSGAIVLT
                     SGGKLKFMGLELEVPGLINTYQEYQKNKLERIKQAKELADELGVPISELGIRIPRKLT
                     TAIESQKNVKLASSNPPEKSGE"
     gene            33567..34694
                     /locus_tag="VQO19_000962"
     CDS             33567..34694
                     /locus_tag="VQO19_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET1349249.1"
                     /translation="MWMEELPNGKYKFFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKINKKLSTKQVESITFEEIYNLFYKSWAQTVKESTKHNCKSVDKKMKEVIPSD
                     TILANLDRRFLQEAIEKIIESNGYITAKKVRHRLRGIFNYAVQYSYIENNEVDYTTIP
                     QKPKTLEELEKKRNNFLTMKEIKALVDVLNRREYHQKYADMVLVLTLTGMRYGELTAL
                     QLKNIDFENNKIEITGNFDSVNKIKTLPKTTNSIRTIKVSESVIEAIQRQIVRLSERF
                     QPLSSDDYIFCFEKWNQPTTIACFIQILKKYGKQAKIEKNLSSHIFRHSHISFLAESG
                     LPIKSIMDRVGHSNAKMTLEIYSHTTEDMEDKLVNKLDTIF"
BASE COUNT         9612 a         7800 c         6002 g        11361 t
ORIGIN      
        1 ttgagcttgt tgccaaactt ccgtcttcca gctggggcgc aagaacatct aaatattctc
       61 cgacttcagc atttacgaga tacacatagc caattgatgc gactccagcc ctatttctag
      121 cgctagtaaa cgatagcttt gtccaatttt catcctttaa tgtaaagatg ggcgaaatac
      181 ccgaattatc attgacttgc caataagttt gtagcttgac cttttgacct cttctgcctt
      241 tgacccaaca agacatcgtg tatgtgcctt gcgagatata aaatccatct tgagcaatac
      301 ctatttggtc tctagcattg cttgaggtca atcgtatcgc tttatcaaag ccagttgctg
      361 gactgtctaa tacatcaatc gtctttgccg tcccagcgcc tgacggtcta aaagtacctg
      421 atgcccacaa tcctctggct aacatcatgc gctttgtacc ccggatataa ttcctacccc
      481 cgacctgcac actcgctatc ttactagaga gctcctcagc tgtctgcgtg agttctgact
      541 tgctggcttt accattggcc aagttggtca gttctgacag tctacgagtc gtcgtctcct
      601 catacgtcgc ttgcgctgac ttcacgccag ccagttcatt cttagtccga ctaagtactt
      661 caacttgctt ggcaatctca gcttcagcct gtgcttgctt cggtcgaata tcgtttgcga
      721 tagttcgttt cagggcatcc aagtcacctg acaaagccgt ctgagcgctc gtagtctgca
      781 acttaaacgc ttcaagtcta gcaacagaat ccagtccaat ccgcttagct tcctgtgcaa
      841 ttagggtact tgcgccagcc agttcatttt tagtccggct aagtgcttca gcttgcttgg
      901 caatctcagc ttcagcctgt gcttgcttcg gtcgaatatc attcgcgata gtccgtttca
      961 gagcgtccaa gtcacccgac agagccgttt gtgcgctcgt agtctgcgac ttaaacgctt
     1021 caagtctagc gacagaatcc agcccaatcc gcttagcttc ctgtgcaagc agggtacttg
     1081 cgccagcatt tcgcaaagct tcctcagcct tgcgcttagt ttctttcaat ggcccgttgt
     1141 caaagctatt aaagcgctga ttgatagtgt cagacagttc tctcttgact tcttcagctc
     1201 tggctttggc aagttcgatg gcatccgtga tagctttctc acgtttgtca aattcagcgt
     1261 caaaggctgc gtctgctgct tctatctgcg cttggatttt ggcttcaatg ccatcttgtt
     1321 gcttaatctg cttggtaatc gtaccctcgt aagaatactg cgtatcattt ccagctttac
     1381 tatctgcgct gatacgacct cttagaccac ctttgaaagt aaagctctga cttaagacag
     1441 gaactttaaa ggtttctttc ttgttggtct gaatggttac ccactgccca acctcaagca
     1501 gtaaatgccc ttggtagttg agattatacg gatagtaagt taggtttttc agtttgtaat
     1561 acaggtcatt taaagcgctc tgggtcatga agacattgtc cagttccaaa gaccggcctg
     1621 tcttcatacc gaccgtcaga gacttcttgt ccgtcttaca agtgatacca gctatctgat
     1681 actcaatctc actcttggtc aagccatgca agaaataact gtcagcgttg atcgtgatat
     1741 tggactcagt caaatcacgg atttccatct tgccttctct gttgaagaaa caagacatcc
     1801 caatcacctg agtcatagcg ctcagcatat ccctaaagga aagtttctta ccctcaggaa
     1861 cttgctcaat atgataacgc atcgcgctga ttccgaaata gtcattcgct aactcaatgc
     1921 ctgttttcag gcagatttcc tgaataacct ctcgtacttc agctgggaaa tgcaaatccg
     1981 tcacgtactc acgattgagc ttaaacatac cgtccataag ttcaagtgtg gttgtgttgc
     2041 ggtttcggtc aatctcaata tcgttgatga agtattcccc catcttgacc cactggtagg
     2101 tatccccaac cagtagacca atctcagggt gcagggtatc cagcttattg aacgtggtaa
     2161 tgatactggt aaaggtaatt ttaccgctac cagcgcaggt tccaccaggc ttataagtat
     2221 cgcccttgat gtagccatac tcaaaactag cctctttgat atcccgtgaa gcatattcac
     2281 caacacgaat agccagcgtc ctttccttgg caaacatggc tctgtcaaat tgtcgtctag
     2341 ttaaagcgtc cattttctta cctctctacc agattaaatt tagcgccaga ccaaggttta
     2401 aacttctcag taaaggtata gctaggagct gtcctatcac cgacatagaa agtctttgtg
     2461 acttggccat ccatggggtc tggataagat acctcaaaaa atttagatga tacagcatgt
     2521 aaaagctgac ttatttctcc ctgagtcatc ataccccatt cacagtctag tttgcgtttg
     2581 gtcgtgatac ggtcacgcac catgtcgcca ttggcattac gccctgtctc tccatcgata
     2641 tcttgaatac cgacttgaaa atatttggga ggcttcacag ccaccccatt gattgtcaat
     2701 tgtgccattt aacctcctaa atcttgagca aggtttgacc tgctcgttca tgctccttgt
     2761 tgatttcttg gatggctacc cgtccgaact catggcctgc gatttggata acgatgtcgc
     2821 cgtcgccaga gaatccacct tgtggactaa caccagccat ggcatttact accgcactgc
     2881 tgactactcg tccaagtgtt tggataaatc ctgtattttc aagtggtacg accgcctctt
     2941 taccagcttc accaatcatg gcgattgttg gactatcgac gataccacca cgggcaagac
     3001 gagggaggct aactgtactt acactaccaa cccatcctag accaggtaag tttctgacaa
     3061 cgcctaaaac tccattaatc attccgatga agccattgac tacattttca atcgttccaa
     3121 gaaccgcatt gaccgcactc ttaaacgctc cacctactgc ctcgccgacc atctgaccag
     3181 cattaacgaa gatacttttg acagtatccc aaacgccttt aaagaagtct ccgatagagc
     3241 taaaggcatt tttaacagcg tcaaaagctt ttccgaatat atcgccaaac cagcttgcta
     3301 ctttggaaag tgcacttgta acatcgttcc atctctcgcc aaaccaagaa cctagtttgc
     3361 taaagatgtt tgttaagcca gtccatgctt tttggaacat gtcagtaaac catgccccga
     3421 tattagccaa cgcactagtc acatctgccc aacgttgtcc gaaccatgag ccgattggtg
     3481 tgaagatatt aacgatagcg tcccatgcac cttggaatac accagagaac cactctccga
     3541 tgccagagaa tatgtttaca atggcgtccc atgcttgctg gaatttctcg ccaaaccatt
     3601 gacctatcgg ctcaaagatt tcttgtagtt tcgtccatag accgctgaaa aattcgccaa
     3661 tcgcttgaca aataccactg ataaaatcac atagtccttg ccatgcagtt ttagcaaact
     3721 caacaacagt gtcccagttt tgatagagca aaacaccaat agcaatcaaa gctgcgattg
     3781 ctgcaataat ccatgttatt ggacttgtca aaactgctaa cgctgcatta aaagcccatg
     3841 ttgcagctgt agcgactcct gctgcaacag aatgtgcaaa ttccgccgcg gttgctaatc
     3901 ccattttcgc tgcatgagca gtccatgcta gagctgattt accaagttct aaagcagttt
     3961 ttcctagctg tgcaattgtt ttacctgaat tgaccacaaa atcttttgca tataaggtgt
     4021 tcaaatagat tgtttcacca aaactgacca acttatcaaa tgtcaatgct ttaatagcaa
     4081 gacctagatt cttaatccct ccaacaatca aagagacctt actacctaac aagctgaatg
     4141 ctcctgcaag tcctccagct tgttctgccc atgataagaa attaatcgtt tgccaagttg
     4201 ttatcaaagc tacgataggt tctttgtttt ctttacacca gtcagaaaaa acggtgaaac
     4261 catctgccac taacttaata gcatccgcca atagtcccaa agtggctaaa aggccacctc
     4321 ctaataaatc tgaaattcct tcaatactaa caccgaatac tcctgataaa aactcagcaa
     4381 aaggttgcca ggaattctcc cagagaatct gaataatgtc aattagccca ttaaaagcat
     4441 tagcaataga gttaatagca gggactacat gttcatcata aacacgactt aagccatcgc
     4501 caaatttgtt aacagacctt tcaatgctct caaatacagg cgcaacagta tctaataaac
     4561 tttggaagac tgatgaaatt ttaggagcgc ttgtcacaac gactttttca aaacctttaa
     4621 acaaacttcc tgctaattta ctaccaactt caacaatggt agatgtcaaa ctcaacagag
     4681 ttgacacaat agcgctaccg atacgaaccg caccagttga ggtaatgacg tcgtagaaag
     4741 cactagaaaa gtcctgagct atgtttccta ctgcctcgga aaggttacca acattatcaa
     4801 acaaagcgac tagcgccctg gtaatgcgtt ctttttgcct tccaaggcca tttgcaatac
     4861 tttcggcaag gaaaacaccg atacctagcc cgatagtggt tattgagcct gtcacttgcc
     4921 ctaaagcata agcaattttc tcagccattc ggttaaaggc attcacaacc cttgggtcag
     4981 tggcgatttc tcccattgtc ttagctattt ggtctaaggc agtcttaatg cgttttatac
     5041 cttctggtct aaatgctgca tcaaaacctt tcttgaagag gtcaaacaac cctttgagct
     5101 tatctccaag accatcaaaa atgctcttga atttgttgtc catgtcggtc aactcgactt
     5161 ctggcaagat gtctttgaaa ggtccgccac cgcctccctt tcctttacca cctttgccac
     5221 cgcctccaga accgcctgcg tcgtcatctt ttggtttttg caagatgtta atctcatcaa
     5281 atcccaaaag acctagcaac tctttagcag ctttcttagc gtttttggcg gagtctccaa
     5341 gattgtcagc aagtcctcct gctgaatctc cagcgtcgtc tactgcgtca gcaaggtctc
     5401 ctgctccgcc tgcagcgtct ttcatggcgt tccccatgtc tccaactgct ccaccgacac
     5461 catctttaac tgtagctttc ttgttgaaca tcaaagcgat aaactcagcg agtttagcag
     5521 tcacgttctt caagaccatc gcaaaagagt ttaagacggg cataatggca ttgataatcg
     5581 gtaacataga gttaccaagg ttcaatgctg cgtccttcat tagcgactta aacaggctga
     5641 tacgaccatt tacagaatta gacaaggtat ctccatactt ggctgtagct tgctccagga
     5701 tagccataag acggatttgt tgctgggttt gaaagtcgag ttggtcccaa ctttgaccat
     5761 ttgagaaacg tttaaaagct tcagtggact taatcatagc cacattgacg ttgattccta
     5821 ggtcctcaat tgcttcggtg ttccctagca aacctgagcg aatccgctcc ataacgtctg
     5881 taatcgtgcg ccctgagcct tcagcaacca ctgccgatgt ctgcaacatc ttagcagtat
     5941 aagcacttag cttgttggtg tccttaataa atccagaaaa taggtttgag tagactgcac
     6001 cgtagttagt agcctcaccc acacccatat tcatagcgtt ggcgttatcg ttaacccatt
     6061 ttaagaaaga ttgcgaactc tcgcccatct gtcgcttgat ttggttcata gacgctgaca
     6121 cttcaagagc tgtctgcgtt gaatacatcc caacatcaag taatttctta ccaaggattg
     6181 caaaaccagc aaacttagcc agcttaccaa acgcactacc gattgagttc gactgttcac
     6241 gaactttggc agtggcattt ttcacttggt cagatgttcc tttgacctga ttctcgactt
     6301 ctttcatctt cttcctgaaa ggcgctatct cagcgtcaat catgaccttc aattcatcaa
     6361 gagttgccat ttatttcctc cttccttttt cgattgtgtc tctctgcaaa atcacgcatc
     6421 cgttccttat gcaacaaaag cgcttgtctc tgtcgttcct gttctactgc ttgttgttct
     6481 tctacaaaca actcaggcgc atattcccag aactcaaagg ccttggcatc tttggataac
     6541 aataaagaaa cgtggttgga tatcatctgc gaaagtctgt atgagtcaat aatcttttct
     6601 ttacgctctt ggattttgac acggttgtag ctttctatca tttccctgat ttcaagcacc
     6661 gtcaaatccc aaaaatcaag aggcttgccc ccgatgtcca aaaacatagg ataaagcctc
     6721 tcaataatct gagttaccgt taagattact tgactactgt cattttcttc ttggaagttt
     6781 tcttgtcctt gcttcctcgt ggagtaaaac ccgatacttc aaagagtggc attaaaacct
     6841 ctgtcatgaa tgttgtttgg tctccaccat tgtccacgta ttcatcgtat aaatcataga
     6901 catcctcaag agaataccca tgttcatact gctgcaaggc gccgtgaact aacaacaaca
     6961 taactttcaa aggcggtaaa gtgaactctt cgccagcttc aggcatgaaa atcttcagca
     7021 agttcatgcc gattttttct tccacagttg cagcttgatg agatgtcaaa cgtagcttca
     7081 actctttttc gtcagtaact ttccaagttg tgtattttaa cgccatttaa ttaacctcca
     7141 acaccgtctg taaattccaa ctctgactgc aaggcaatct taagtgtgaa ctcgataacg
     7201 gcattgacac cgccaccgcc aagcttaaca gatacttggc cttcaaaatt gaccttagta
     7261 ccgtctgggt atgcttgctc gaagtagagt ttcttcttgt cgtctgctgc cttacgcaat
     7321 acacgataag gagcagttgc gcttgaatta ttataagaga acttgtactc aagttctcct
     7381 atgtccccaa taccaaactc gtacttcttc actgtatctt caagagtagt attttctact
     7441 ttttcgagtt caataccaaa ctctggcact tctttcaatc caacaagttt agtataagtt
     7501 cctttagctt cgccataaga tagcgtaatt ccatttgcta acatgtttaa ttctccattc
     7561 taaattgaaa aacaagctct gagtctaaat caacgacacc ttcaaaacgc atgaccttat
     7621 gtctcaaatg agacgggtct ggcacgtctt ggcagtcggt tcttcgcaaa cctaaagact
     7681 caaaaatctg attgatttta acagctaact cactagtgct ggtatcatca aagatatcca
     7741 ccttgtagcg gatagaggat ttttgttcct ggtcatcaaa ccaatcaccc ggcttgtttt
     7801 gttcttctaa aaaaataacg actgggaaag tctcccaatc gctaggataa gtatcagtca
     7861 cattatctgc gaccttttgc aattctttat aaataacagg cttgatatta atcattttat
     7921 ttgttctctt atctttctac ggacataatt cgaaatattc ttagacacac gctcttgatt
     7981 gtctctcaaa gctggataaa gataaggctg ggcaggttga ccatacatct tgtagaactc
     8041 cccaatcttt tgaaagtggt aaggtcctac attgatttgg tcttcatgca cataccacgg
     8101 actagacttg taagttacgc tgacctctgg agagatacca gaatggctag cttgtccttt
     8161 tggtcccgtt ccaaactcaa cgtaaggagc gtattttagg ttggtgtaaa cctcgcctat
     8221 agccttatct ccgtccattt ttgccctagt tttgatacta gttataagct ctccatctct
     8281 cgctggtgcg agtcttcttg catctgcttg gacaaccttt atagtagcat tgtgtaccgc
     8341 acgtaagacg atatcctcgc cagttttttt actagccaat cgtctacatt tagctataag
     8401 cctatctgcc cctagtagct ctgacacgct ctaactccaa aacttgatga tgtgtgtaga
     8461 cctttttaga aatgacctta tgagtcactt ctgtctggct atcgatacac acaccatctt
     8521 tcactttgat agtagctgat ttgttggcat tggcattcaa aatatcattg acacgctcac
     8581 catacaattc agattgcaac ttgctactag ctggccacaa ttcaagacgg actgtctcag
     8641 cttccttggc atacccttct tttgcgacac cttcctctgt gacagtcttt tcaaaccgtc
     8701 gcatcggata aggtttcagt ctactctgct tcaaaaacat ggcctgccac ccttgctaat
     8761 ctgtgcatgc gtatacgctg taaaagaccc gtagacaggc ctttttctcc gtagactact
     8821 gctataccac cttcggttct agaacgctct ccttccgctc ctgagcggtt gtggagctcg
     8881 atagcaacct caggtatcaa aagacttaaa gcaggtgtca aagatgtgcg attagtctct
     8941 gacaagataa gatttgtagc ccttgtttgg agcaacatga gaagctgagt atcttcttcg
     9001 cctgttaatt tcttcagcaa ctctatagac atatcaatcc tcttctaaga actcaggttc
     9061 agggaggatt ttctcaagaa catctgagat agcgacaccg ttgctggcaa tattgtcagc
     9121 cagctcaaca tagcgctcct cagtaatctc aagctcccct cctgccagtc gtttcacatt
     9181 tgattcccaa tcatagaaat cttgtttaat tttaaacttc actttttaaa tcctccagca
     9241 cctctacaat ttcggctttt gataacttat aggcgccagc tatgccagct tctttggcta
     9301 gattcttcaa ctcttctaga gtcttattct ctaaatcaga atactggcta acctgctcct
     9361 cttggatata atgacgtcgt agcaataagc tcatgccgtc acccctcacc gaattttaca
     9421 actcgtgtag ggtcgtaaag gtaaacacca tagtgttcat caccagtgat aaccgttgtc
     9481 tttttaagga tgtcacggtc tgtttcgata gccacatcac gttttagcat gataacaaac
     9541 gcaccatatt tgttggcatc gtctgtctga gtttggctag gagagacttt gacgataaat
     9601 cctttacctt catcaacttt tttagaacgg acgatttgca caccggcaac ttcaccgaac
     9661 gttccggata caaccatatc tgcaccaagc tctgaacctt tagtccattc ttttgctacg
     9721 tcagttttta gcttgatagc atctttaggg ttgatgatag caacatattg cgcatcttct
     9781 tcgtcctcaa aaatctcaag agctttatca attgctgcaa gagttgtagg agtttctgta
     9841 atatgttgtg ttgcagtttt agctactgcg accaaatcat catcaatctt gttagcaata
     9901 gccaaaccaa gctgataagt agcttgacct agtgggtcgc caagacctga caaaagagct
     9961 tcatcggtaa tttcataacc tttagcagcc tttttgatgg tcatagtggt ctttttagta
    10021 gtcaattggt ctggagaaat agcttgacct tctccaacct ctgtcgcatc tcctgcgtac
    10081 tcccaagctg gaactgtcaa agtgttccct ggttgtcctt ggagcgctgt ttccacataa
    10141 gcaagcggag tgaatttaat caatttaggt agtttagcgg aaaccatgtc cgccatcact
    10201 tctgggttaa ccatagtggc taatttagtt tgtcctgctg tcatttattt taacctttca
    10261 atttcttata gagttctggg ttcttttgat agagttcatt tcgactctga taccccatac
    10321 gagcaaattc ttcttttgtg ataccgtcac tatcgactgg ggcttgcttc attggagctc
    10381 cgccttttag cttttcttgt acgccttttt gcacggcttg ctcccatgat ttctgcaata
    10441 cagcgacaga ctgtgatacc gtctctgcgt ttgtcaaatc gactacattt actaactcaa
    10501 caggtaagtc acgttcactt aacatcgctt tagcttctgc ggtcaattcc ttgcgagcaa
    10561 tggccttttc acggtcggct agttcttgct cacgctgatc caactgatat ttctgcttct
    10621 catcagcgtt catcttagca agcttcttcg cttcgttttc tttagcttct tgctctgatt
    10681 tccacttggc aaacttctta tcgatgatag cgtcgacgtc tgcgtccgtg tacttcttct
    10741 cgtcttgcgg ttgttgtgca ggttctgcag gtaccttttg ttcttcaacc gtttcgactg
    10801 tttgtgtttc ttcgttcatt gcgaacctcc tatttttaaa gtcgtccccg actgtaattt
    10861 ccatagcttt tagtgtcgtc aatgcttgga caatataaaa accgtacggg attccatacg
    10921 gttagggcat aggaaaaccg catcaaatat gacacggttt atagcaattt acagtaattt
    10981 atagcagtct attcctgcaa gtcaagatgt tggatcacct cctaatcttt aatggcacga
    11041 tttgaaacct tggcgtaaac atccacataa gtctcattct tatctccgtt atgcgtaatt
    11101 tctgcataat ctccacaagg ttcgcttgat gtaattgcgt tcgtactaac aagagctttc
    11161 cagttttgca gggtcttgct aaaccaaact acaaagcagt cttcttcttt gatttcacga
    11221 cctgccaagc gtgaaaattc ttgcgatgcc aattgttttg ctttttttaa cattttactc
    11281 ctccgttttt tcgtatgttt ctgcaaaaat atccggcttg catggataat attctccttg
    11341 cacgcctttg ataatataat cccctttttt agctaccata tcaccttcaa gtgtagcaat
    11401 ccatatattc ccaagtgcat caaaccaaat cttattttct gcaaagtcaa ttacctcttt
    11461 atggttattg ccgttccact gcacagcctc gaccactact ggttttttac ggtatttcat
    11521 tcctcaatcc tttctgggta cgaaaaaagc acttagattt ctctaggtgc ttaagtaata
    11581 aattgcattt ttatattttt taacacgctc gtagtctgta ttggtaacag atttcaaacg
    11641 tgataaatct gagttatgtt tcaaatctgc aagttttaca actcttgcta aattatttga
    11701 ttttactttc ccaagatatt cttgataact ttgacctttt ttctttgtca aaatttgtac
    11761 cgctgtaaca acttcatttg acaagccaga cgcgaataaa tcggcagcag ttatatcgct
    11821 atcctcaatc acatcatgta aaagagcgac agctttttct tgttcagtgt tgacttgact
    11881 ggccacatag agaggatgct gtatgtaatc aacacccgct ttatctacct gccctgcatg
    11941 tgctttttta gcgatagcca aggcaatatc aatcatgccg ctaccatcct gtcaatataa
    12001 gtaaatgcat cattttctga aatttcttca aaatccgtaa agtcattaaa aaagatttta
    12061 ttaaaccaat ccatgctatt aacccacttt ttttcaatgt caaaaacttg catgacacca
    12121 tcaatcaaac gaagtacttg agcattgttc gtcgttgtgc ggtagtattt aatatctttc
    12181 atatcacttc accctctcta tatttttagg aatctcaagc ccattgctta aatcaagcat
    12241 ttccttaaat aatttcatgc gttctagatc agatgtattc gtatcacgat acttctcata
    12301 gagttcatgt aatgaaccat tttttaagtc gaaactttcc tgagtatgat actgcatttc
    12361 aaagttgata ccatcttttt caacgactgt attcacacct ttgtatggtc catctactag
    12421 ccaagtgttt tttactttta caattttata accttctgcg ataagcttct gtttcatctt
    12481 caaatactct tctgtaaaag tatcggaatc gaaaatagtt gtgtacctta aggcgtcatt
    12541 aatcttactc acggcttttg acaaacttat attttcaact aggctatctg caataatttt
    12601 acgtgataat gactcaactg ttttcttcct aaattcaaga cctgccaatt tgttttctcc
    12661 tgcgatacgt tgcatatcac ttgtaatttt tggctcaact cctgaaattt tggacaatag
    12721 ttgttcgcta taaaatttcg ccttggcttc tcttgtatct tgattataca ccttttcccc
    12781 gtctttcgca acatacttac tataccactc tttataagtc atatcggcag gcacgtactc
    12841 aactttacct gtctctggat tccttgctct gcgcttcaac ttgctgtagt ctgcgtcctc
    12901 atcgtatccg acagtagtag acctgcacca cggatgcata ggtggacaat tgacgccagg
    12961 gacagccttg tccctatcat agacctgatt gtcatgctcc tgacaaatcc gtgatgtacg
    13021 cttgtctaag acggccacaa agatatactt ctctatatct gcttcttcat agctgagtag
    13081 ttccatttgg ttatgaaaaa aggctgattc tgtccgaacc aaacgtcttg catcgttctg
    13141 acctacattg aacctctcag caattgcttg tgcagtttct cgtgtatctc ggcctgtcat
    13201 gaggctcata agtagttcat cttttatgct agaagtaagc ttccccgtat tcttccagat
    13261 gtctgtagag taggtacttc cgtcacctac ccaactgaaa gactgtagat gtttaatctc
    13321 gttctcagga agcccagaaa agccatatgc tagtcctgtc tgctgctgca ggtcaaaggt
    13381 agccttgtag taactatcct tcatcaggtc gctataaaag gcgtctgatc ctgtcttttc
    13441 tgaatgatag atagattcac gcatacggtc taaatcatca ctcaaacgtt ctagacgctt
    13501 catacggaaa gaataagccg gactatctaa gtcagccagt aatctttgga tgttcgggtc
    13561 attcggtctc gcttcaagta ctttacgaag ttcattcaga tttttcttgt ctttcatgtt
    13621 cttcaagact tgtctagctt ctacctgact tagaccataa tcacgttgga acttatcaaa
    13681 aatcttattg acttccttat ccaagtaagt cttggcttcc tgatagacct tatcgaactg
    13741 gtctgcctgc ttttcggcct tgtccatctg ctggtaaatc agattggctt tcctcttcgc
    13801 ccaatactcc tgattcttca tcctctacct cgtcttcggg tttcgtgttt tcttggttga
    13861 acatcggcat gtcttccatg ttcttctttt tttcttcttc caaggcttcc agctcagcgt
    13921 cagggtcttc cacaaacggc aagagagaaa taagctgtct attggtcact ttgccttcca
    13981 agttgttcac aatctgagag atttctaaca agttcttagg caaaccacga ctgaattgtg
    14041 gaacgattga atgagactct aaagcaatct gcttcatgcc taagtaatga gcaaaaatcg
    14101 caatacgctg acgcaatcct cgcttatagt tcgcttcctt ggtcttagta atcatctcaa
    14161 ggcccatcag cttaaattcc atggctacgc ctgatgtatt ccctgcgaaa ttctcatcag
    14221 tcaaattagg cacatggcta aatgtgtaga tgtcctcttt aagagctgta cgcaagattt
    14281 cagtagcact ttcgtccagc gtattcttca agaactcagc ccttgcacta tcgcccggca
    14341 attccaaaag accttcttca gaaagaatct tcattgctac cttagcgtct tctggagtgt
    14401 ctgctaactg cgtgccatac aagacaagta tagactctac agcctgttcc ttatcattga
    14461 cacgattccc catcaaggaa ttataagcgt ctatcaagct aatttgttgc tcatagtcac
    14521 caattgcaaa gtgattgttg cgatattcga taattgggat ttgaccaagg ttgtgaggtg
    14581 ttgcctcctc gctctgagtt gttcctgaat ctgtacttct cagcaccatg tgatagtgca
    14641 gattttcggt aaagacctca gcctggtgct tggtagtgtc tttcgtatcg tcttttactt
    14701 catagtaata gaccgcaaac aaaggcttcc gctcaatact atcatcgtag accatgaaag
    14761 tattctccgg atcaatacta gttgaatcca actcagccat accctcttta gcatagatgt
    14821 actcgtaagc acgaccatag atagccatgt tcaaagcatt ctgagcatct acttggtcaa
    14881 tctcagcacc atcaaaggct gtaagtagtt catcgatatc accgtcagca gtattgttat
    14941 acttgatagg attgcccata aaatagcccg tagccgtgtc tgcgatatcc ttggcatgat
    15001 tggctaccgt cttgtaatta ggtgcgttca cgttgcgtct cgtgtgttct aagatagcat
    15061 gctcacccaa atagtagctt ttaagcttct tcaaatgcga gccttcagtg ctatgtatcg
    15121 ttatcaattt gtaaatcagg tctttcttca aagaaccctc atcatatcca tcccgtggat
    15181 aggttaaata ttggtacatg tctttcctct ctatagacca taatcagaac gtctgcggac
    15241 ggttgctttc ccaccttcga tacattgaag gctgtaacgc aaagcgtcca tcaagtggtt
    15301 gtttttatcc tctggtttat tcaaccagtt gccttcttta tctcgctggt agcaataact
    15361 ataaaattca tccatgatgt ttttacaatc tggatgcaca taaatagcgt atccttgcaa
    15421 ttttgataca cctgccataa tactatcctt acctttccga ctctctttta ttctagatat
    15481 gccatgttct gacctgagct cttcaatcag ccgtgactct gcgctatcag caatgatttg
    15541 tgagcgatga taacctttgt cctttatcat cttcgcaact tctttggtta tcaatccgac
    15601 tttatacgcc tcatcaaaga cataaatctc tttcgtcgtg tcatttatca acgaacaaca
    15661 caaagcggtt ggatcgtgag taaaaccaaa gtcaagaccg atacataact tattagctga
    15721 atctcgtagc aattcatcct tatcgaaatc cttgacggtc acgttctcat agattaaacc
    15781 ttcagcaact ccccattcac catcacaaac gattctagca cgtctggggt tcgtatgata
    15841 caaatcctca tagcgtttga tatcgactcc atcaagccac tcattgcatt tataagtggt
    15901 tgtagtagcg aatgtgtcag cccgtctcgt ctcttcatcg aagaatacac gcttgagcca
    15961 atgcctctca ttccacgggt taaatgtgac tgtgatttgt ttaaagaaat caggtacatc
    16021 taggctacca cggattgact caactactgt actgaacttg tcttcagtct caatttgata
    16081 tgcttcctca aaccatgccc aacaaagact gccgacatcg accgtgatag atgtgatttt
    16141 gagttcatca tccaaaccac ggaataggat tttttgacca gtcgctttta tggttatttc
    16201 aggcaaagat tcattgaatt taaacaaatg agtcacaccc aacacattac acgcccattt
    16261 aaaatccgta taagttgatt gcttgttggt attcgagtat ctacgaataa caagcaagtt
    16321 ggcccaggga tacttcaaaa gacggataac ataattcaaa gcggttgtct tggacttctt
    16381 cgaaccacgg gaccctttga ctacacgata aagacttctt gagcgccaga actgtccgta
    16441 cccagctcct actgtcttag gtaggtcgat tacaatatca ctttgtttaa tctggtatgt
    16501 ctgactcatt tgcaaacacc accgttccag aaacgtctgc ctctactttg tctgtccaaa
    16561 gcctatgacg ttttcctaat agttcggctg ccttgattct gtcttttgct ccaacatcaa
    16621 tatccgtaat cgtttgaccc aattctccga tgcttatcaa agtctgttct tgcgtctctc
    16681 ctcgcattac cgaggttaga taactaagga cttcttgctg gtctgcgatt ttttcagaat
    16741 caagctgttt caaccgttca tctatataac ttttaatctt aggattcttt agtaacttat
    16801 gtccttcaac gcctgccact ctatcactag aaacacgata acctgctttc ttataggctt
    16861 ccgtcgcatt acctgagatg atgtactcat ctgcaaatct cttttgtttt attctcaatc
    16921 cactcaattt tccatcacca cctttcaaac aatcaaaaaa gccacacgat gtgcgacctt
    16981 cttgcaaggc gactacaacc ttgcgtgcgt attaaatttt gacttctttt tttatttttt
    17041 gtagtcttta aaacctctga gggaatcaaa ccctctagct tataacttat ccggaatata
    17101 attagctacg caatcatgcg aggtccagtc gcttccgcaa ccatttttaa gttaatgagt
    17161 gatatgtgaa tccccaccca gaagatttaa ctcattctgg gacacaaaca ctcaaaggag
    17221 aggggaggac ttgaacctcc aaggccatta cagccccctg acattacagg taaccatcta
    17281 ccaattctga gacctctctt ttcaattctt gatactacca ttctaacaga tttttagaac
    17341 cgtgctgttc caaaaagtcc cataagctca ctatgaggtt agatgacttc ttccaaagct
    17401 aagaccgcct cattttttaa cctgtagtag gttgtacgac tcatattcaa atcataacaa
    17461 acgctatcag cggtgccttt gttgatgtaa gtcattctta atactgccct gtactttgga
    17521 tttttaagcc tattgatcat tctacctaat tcaagttttc tgttaatgac ctctttagta
    17581 tcctgctcta tagcctcttt catcactacc aactgagtat agacgtcatc aacttttcta
    17641 gtctgtccgc cttggacttt gacgtcagtc cacttggggc ttgagagtaa acctgcctca
    17701 agctcattga tttcatctat acggctttga atgtccatgt ccagatcctg tagctctttc
    17761 aagagctctt tagccttgtt cactctctat ctccttttgt ggtataataa tattattgag
    17821 attatagctg agacagagag tgtcttggct tttttatcgc acaaattcgt tgaccaggtc
    17881 acggataaag aacttccagt cggattctct aaacgtcaag aaacgatccg cagtaaaatt
    17941 tctaagcctt ttataaaaga gtatctttag ctggattgac tcgcctacag tcaggaagac
    18001 accagggaaa cgatgtaccg aatgcactct atttccatac ccagaaatat ctaaatgtat
    18061 tatcgtttct ggatatatgc gccctgtact agcttcaact tcgaactcaa ccttaacttc
    18121 ttctacaatt ggaacttctt taaaaattgg tcgtgcagaa aatattggcg acggtgtttc
    18181 ttgctttttt cttcttcctg aatatggata tttacaaggt ctcatttgcc gtcctcccca
    18241 ataatatcca atactttcaa aagtttatct actgaatttt gagtgataga aatatgatgt
    18301 tctcctaaat tgtaaggtgt tcttaaaaac aagatattag ggcctagaca gatgcgccca
    18361 atatcatcta tgttgataag ctcatcttca gtatgtcctc tataacaaga ttgtatttta
    18421 acaaattttg tcatttattc cacctcctct atatcaattc cttcacaatc aaacacccag
    18481 ccgaactttg cttcttctag ttctttttga gtacctttat aattcctagc tgttatatct
    18541 tgactaaaat aaagagtact ccctgattgc gatttgacca aaggctgcct attttttaaa
    18601 gtcaccaaat accgcttctc ttcctcgacc tcgtagccgt caagccaagc aagacagaat
    18661 ttttcgatgt tattttcgta aaaccaatca ggaactttct tatcataatg atcttcaatt
    18721 actctcattg caccgtaaac atgaaaattg tttttctttt taaattctat atattccgcc
    18781 acaaactgcg gaattttgac tttttggggt tcgtctagtt gtttcaactc tttcaaaaaa
    18841 agttcaacca ttgaagtata aggtacaggt tcataaaaag ggctgtgttc attccacaat
    18901 tcttcatact tcttaatcaa tgccttaata ttcatcttag tttcctctat aaatcaaata
    18961 aactgcaata attacccgag ccatgcttgg cgaatagcca acccaatcat caaactcctt
    19021 agattttggc aaccaatcct tagtagatcc caaatcatag tctgtaggct tttcatcagc
    19081 gaagatgcat tccatcgctc ccataaacgt cataccatct tctgccattt cccaaaaata
    19141 gtccgcccgg tctttcaccg cttgtggtaa attttgcttg ggaggttgcg gcttcccgtc
    19201 ttctaccgtc cagttgtata ctgcattaac ttttttcttt aactcttcca tcacttcaac
    19261 tccttgtcct taatttctcc agtaagtcta ttttctaaaa tgtgacttgt atagcaaata
    19321 tcgtttttat aagtatagtg atcaacggtt tcttcaaccc attgattttt agtgtacggg
    19381 tatctgtttg gtcgtttcaa tttaccacct cacatataaa tatttcgtat caatatcttg
    19441 ttctaaaata cagtccctta acgatctcaa aacatataac gcatcattga tcgttcccca
    19501 tttatttgca ggttcatatt gtacatattt ttcaggttgc ctttccaatt cagttatgcc
    19561 acgtttaata ttttcaaaaa tatcagcaac attgtaaatt gtgccttggt cgaaatccca
    19621 atccatagcc accctaaaca tttttccaaa attgtaggtc ggagaactat atctaggttc
    19681 agcaatacaa atataatctc cactctctat tttcgctaag atttccaaat cataactcat
    19741 tactccatct cctccatctt tactttatac attcgatcac ctcgatactt gctctcgagc
    19801 tgagccttgc attttgcagc atcaccctct ttcttaaaaa agtgggtttc gtctaccata
    19861 ttgtcaaaat atagtgttac tgtgtatgac atttttacct ctttttttca aactgctacc
    19921 gtgctaccga taaaatctaa aaaaataaaa agttttttca agaatcccta ttttataggc
    19981 tttctttatt attactatta ttttatatac tttttttaaa aatataggta gaagagtagc
    20041 attatatata aatattaaat aaaagtcagt aatatcaagg ggttagactg ctaccgatgt
    20101 gctaccgatg tctcatttta tcggtagaat gctaccgatc taccccctca actgctaccg
    20161 atgactaccg ataattttta aattgctacc gattagtttt ttccgaattc ttcactctta
    20221 cgaacccttt tgtactttta cctcctgccc ggaaaacact ttttttccaa tcaggatgat
    20281 tatccatgat catgttaatc ttcgttgaca acttcctgtc attcgaattt ctcataaata
    20341 agttgtacat catttcacga gttgagacct tatctagttt tttgcttcca ggatcaaagt
    20401 cgctactatt atcgaaatat ttacttgtgt attgatgttg ttgctgaata gaccagtttt
    20461 gccaattttc agggacgggc atatcaagat attcaagcac ttgtaattca acttcatcac
    20521 gatacatgaa ctgttcacgg tagatattca attcatcctc tgtattttca tcaaacatca
    20581 aattagcacc agcacgatag attgtaacgg cttcgcccca aatttgttcg attgtatcag
    20641 gatcgatttc cattggatgt ttcttttgct gcctgctatc tgccataatc gggagaaatc
    20701 gacgttctcc ggttttgtcc ttcaggtatt ctgtttggtt agtagttctg gctataatga
    20761 agtttttggc aaactcttct gtgcgtttca tgtagggctt acgataccgt aagctagttt
    20821 ttgatataaa ggctttcgtt tcagcaaagc tcatccgatt actggccacc atttcatcat
    20881 cgttgacgat tagactcttt aacataatgt cgtaattatc tttattagag aaatcagtca
    20941 cggcatccgt ataccattcg ccacccaatt tttgaaggag ggacgttttc ccaactcctt
    21001 gtccaccaac cagatccaga acatagtcaa acttaacgta tggatcataa actttagcaa
    21061 ctgcaccaac tagccacatt tgagcgattt tagaaactaa agggatatct tcagcgccga
    21121 gatatacttg aagcatgcgg tcaatccggt ttctgccgtc ccacttttca gctgctctct
    21181 ccatatactc aataactgga ttgtatgatc tttctgaaaa gaaagtctcc atgccatcaa
    21241 gcatcgcttg gtttgagaaa gcaacaccta acacactttc aaagtaaact tttacgactg
    21301 aatcaaagtt agaagggagc tcaccttttt taaaaagagt gttgccgatc ttgatatctt
    21361 taaggagttc atgctcttgg gaaaaatcgt tgtgctttag gtaaatactc aactgatcat
    21421 cagctttgaa agacatcaac acattacttg gactgttggc cttgatgtct cccttggcag
    21481 tcgttatcat cttaggttgt gagtcaatac ttactacatt accaatcaca atcacctcct
    21541 atctttttta atcatacttt caatagtacg catcatttcc ttttcaggca aagggtttgg
    21601 actatttgca tttgctaatc ttgcaagttg aacaactaca ccatcgtcga ccgcacgata
    21661 taagagacca cctacgaatt ttgctagttt gtcatttcgt ccaccttcat caccaaaacc
    21721 aagggcgatg gtttcaaaga gatctgtagt ctgtgttcgg tctctagtat gtgaacgtct
    21781 aactaaatcc ctaagaccgt ccttaccatc atacttatag ccgtgagttt cgccatactg
    21841 tttttttata gactggatta aatcttttga aggagtgacc atcgtgccac cttccttaga
    21901 cttttccaga tcccactcat actgcccttt atctgtggca gagggtgcga ctaacacata
    21961 attattttcg tgagccttaa tatcaacacc aggcaagaat ccaatcatct gagtgatcgg
    22021 ctcatcttct cgtttgaagt agaatagatg tttaccgcca ctagccgtct tagcttgcag
    22081 tgtcggttcg attaaattta gatgtttcca tttttttagc gattcaaaac cgttcgattt
    22141 gccgtgtttg tcaatatcaa tgacaaagaa gttggtagtc tttagggcaa tgtttgcatt
    22201 agggtagccg tcccaaaagt tttcaatctc agatggagtc atggctggct tatcagcaaa
    22261 atcaatcaaa ggcatcttgt ttttaggatt gattggaatg actgagaacc ctaacttttg
    22321 atactgtaat gcgtattctt tcatcgacgg catgattact tctcctcttt gtaaatataa
    22381 acaagttctt gggccatata atttgattga tattcatctt cagtcgtttt taaataaaat
    22441 aacaacgatt gataagcctc ttcaaatgta ttgaatggtc ctaatctttc atcagtttca
    22501 tcaatgaccc aaaacttgct attttttaga aagggaggtc atcttcatca atatcagctt
    22561 cagtcagcgg ttgtgcttct tcttcaaggt catagtttcg gaactcacgg ccatctttcc
    22621 ccttagtcac agagataaca aggttgtagt aagagccaac tgccttacgt tgtagagcct
    22681 cttccaaggc tttaccgtct tcttcatttc cttgcatact gtcgccagca aggaccaagg
    22741 ctttgataaa gaatttcatg gtgcgttcaa ctgcccagtt aaggtcctta ccgttccatt
    22801 cagtcagtgt gccaaatgtt gcaaattcag agcgtccact gtaatcaccg ccacggattt
    22861 caaattgata accaaggctt tcccagcctt tgtccgatac gttgaaggtt gctttcttca
    22921 ggactactgg ataagtacca gctgggattg gtgcaggacc gttggcgctg tctttgcgtg
    22981 ggtcaaagcc ctcttttttg attgattttg cgatatctag taagctcatg tgtattctcc
    23041 tttatttctt aaaatagttc atcatcagag gcaacttctt tcttaggcgc ctcttttgtc
    23101 ttttcggttt ttgcaggttc aacagcccca cggatagttg ctaagatttt caaaatagcc
    23161 ttgtcatcaa catggttcac atagtaggtc ttacgcttgc ggtcaacctc acggttgtag
    23221 ttgttgccga gtttttcagt gtggatcatc aaatcagagt ttccattgat aagattgaca
    23281 tacttatctt tcaagcttgg tttgtctttg gtggcattgc cattgtcatc atattcagat
    23341 acctgacggc tgatgtaaat aacattcatt ggcaatgctt tgaggtcaat gactaattct
    23401 gtgatagctt ggttaaagaa gtcgtatcct ttgccgtatg gaatttccga caaggatttc
    23461 aagcgaggtt taccaactgg ggttaattca tcacaaactg caatcttaat catttcaata
    23521 acatcgtcaa ttacatcaat aacgactgtt tcataagagt gcttctgtgt ctggagagca
    23581 agcaagatat ctccaagctg cttaattact gaattggtaa ttcgtccctt gtcatctttt
    23641 tcattgatca gctgaatgct tggaacagtg ttagcttctg cattcccgtc tgtgttcaaa
    23701 acgattggat ttgggaattc atttgcaaga taagactttc cgctcatggt ttcaccgtag
    23761 atgaaaaaat ttcgtggggt atctttagga acttgtggtt tatttgctgg aagtgtaaat
    23821 gccattagag aacccctcca ataatatcct taatcatgtc ctcaattgat gaacggtcac
    23881 gcttgatagg ttcaacttct gatccattcg gataggtcaa tttgtattcc gcttcaactg
    23941 cgacaatttc acagtcaaaa gctgcagcaa gagccttgta agtctttttg ttgtcttcgt
    24001 attttttacg aggaagcttc aaacaatatt ccaagctaca aaagtcagct gcaaatgcta
    24061 aagaacttct gtccttgtaa gaattaagaa attctccagt tttacggcta cgaaatacga
    24121 tcatttcagt tgttttattc attttgtttt cctctttttt ttaactttct ttataataaa
    24181 attcaattac atttacatca tgctgctgac gacttcctgt tatgcgccag agcaattgtc
    24241 gataatcatc atattctcca gaaccttctt ctactggatc caatacgaca atagtttggt
    24301 atttgtgttg caagccgtct actccgacac ctaacacttg actagtagca accacgaatt
    24361 tcttataaag tccttcttga atatcgcccg tccagattcc aatttcagga tggcgctcgc
    24421 taatgacgtt gacaatctgc ttagatttac tgacaatcaa catatcgtgt ggtgctcgtt
    24481 cgattaaacc gtcaagttgt aacatcaatg gcgtatccgc atttactggc tttaattttg
    24541 gaaaatcgac tgctacgcct gtttgattaa ggtagcgttc aaaggtcttt cttccaaacg
    24601 attgcttggc cattgcagtt ttgccgtcca ctgttacaag atttagtttt ctaaattctg
    24661 caagtttttc tggattgcca gaggcgactc tcttttggta aaacttaatc tcaaaaccgt
    24721 tattctcaac tgcattctca attccttcaa tctcttccca gcggaagaaa ttaggcaagc
    24781 tcgagatata actttcataa ttttgaaaat cttcccactt ctcttttgaa tagctaaatg
    24841 gatcatagac catttttcca tgagtctttt gccagtcaaa tttattattt ggggttgccc
    24901 aaccaaatac cgttttttca agcggataga aattttgtcc ttttttccga attggtgtcg
    24961 ctgaaagacc tatcgtgtat tttcgcttta ttttgcgata taaggccact tgtttgtcag
    25021 aagacatatt ctgccattcg tctactatca gcacatcaca atctaattta tgcccctttt
    25081 tgacttgatt ttgaagatat ctatctgtct gaatgataat ctcaacacct ttatcaaaat
    25141 tcataaactt gactgcatct atccaaccat tcagaatagc tagtcgattg tttgtgatga
    25201 tgattttttt agctttttta tgttttgcaa tagcaagtgc acagatagtt ttgcctctgc
    25261 ccccaagagc ctctaaaaag attccattag ataaatgttc acttctttta atcgcttcag
    25321 cttgccactt tcttagcgtt attgtgatac tcactcacca cctttccgat atcatgaacc
    25381 acttcttcaa tatcatttct cattgcccaa aataatccaa gtcttgctgc tgctcgaata
    25441 tcttgatgat gacttttttc aaatttccaa aggtctaaga ttttcaaaag atcgtttgga
    25501 atatccgact tgtaacctgc attgaattga agaatggcac ctggatagca aagttggata
    25561 taggcgatgg tttctgccac gctattatct ttcgacttgt cgttatccct cgccttaaat
    25621 tcttcaacaa taactacatc gaattcaaga tttgttccga tttcgtgaaa ccaatcagcg
    25681 aaacctctca taccataaga gacaacccag ctatcaacta atcttgcatt atccaacaag
    25741 acaactcctg ttgtgctggt ttcaatttta ttactgcttg gatcaatagc taaaattttc
    25801 atcaaacacc aactttctca gtcagcactc ctggataaag ggcagtgtta aaccaatttt
    25861 gtttatttac ctttgcaaag gcaaatagcg atttaacttc ttttgcttgc ttctcaaatt
    25921 ttcgaatatc ttcctccgat tcaaagatag gtttttcctt gtatttagca actgtgacca
    25981 gcttgtattc cggagtgaat actggctttt catttccttg atcaagattg gtttcgtcta
    26041 cttttacaaa acgaatcgca acatcaaata gaaaaccttc agtaacaagt acttcaatcg
    26101 attctggtcc aatcacaact gctagtgaat ctgttactcg tgttttattc atcaattcca
    26161 ttacttaatc accaactttt ctgtccggac aagttccgca cctttgactt tcttgccaga
    26221 tttaagcaac tctttgagtg tttttttgtc cggcgcaagc gtcacttttt ttgtaaaata
    26281 ttttttcgga aggtcgtctt cgttgacctt gactgattct ggattcttag caatttttat
    26341 aatcagggca ccactcttaa cttcggtttg ccccgtgaca ttcatagctg ccataatgtt
    26401 atcctttaca taatccagct ttttctgtgc cacctgtttc ttggctttga agctctcttc
    26461 ctcagccttg tacatggcca cgtcggcttc tagattcttg ataacatggg catatccttc
    26521 tgctttctgt tcgaattgtt cttgccaatc gatagcctca agtgtgtccg tttttgtttc
    26581 gtcatcaata tccatttgat aaattgtcag aaactgacct gtcagttcgt ataaactagc
    26641 catttttttc tacctctctg attttgtttg tgagttttgt tagtccaata cctgatttgg
    26701 ttaaatcagc gttggacgta aataaatgat tttgattcat tctagcaatt tcgtttttag
    26761 ataaacatgc caggtttaaa atatcatagt ttgttttatc accgtccaag aagacaatcg
    26821 aatgcccttt tggtattggc ccgtgatgtt cctcccaaac cttgcggtgt ttcaaaaccc
    26881 attgattagg ttctccaatc ttttcttttg gataaccgtc tgttgtgtag ttgatagtac
    26941 cgacaggtac ataattcgga ggtcgattac cttttttgaa ctgcccgccg ttttttggca
    27001 tattggggta cttcttcccc ttattgtgag gagtctgacc tttctcgaat cttcctgtca
    27061 aaccactatg tagattatta tttcttcgat aactcttaat ctgtttctca gtcagtgata
    27121 atccaaattt taggttcatt tcatttgcga catcgcgaga aatcttattt ttttggattg
    27181 acacaaggta atcatgttgt tcttttgtca acaatttacc ttgatatact tttccaacag
    27241 gtaaccctaa acgtctgcgt acttctccta tttgagtctt ggtataggtc gtaccaaatt
    27301 tctcatttag taacctggtt acttcaggag ttaatcggcc agggcatatc tcatgcatgt
    27361 actctgtata ctcatccttc cagcaaagcg atcggggcat tatcctcacc tgccttatct
    27421 ttgaacttct tagcatccag ggcgagctgt cctgcttgta agatttggct agagatagcg
    27481 accatctgtt ttgaacgttg gagttccgtc tttaattcat ctgcagtaag atccctatcg
    27541 tccaatgttt ccaactgggc gaaaagagta ttggttaaat ctgtcaattt atttcgaacc
    27601 atctacttcg tcacctcttt catcaattta tttgcttctt tgattaacaa acgcataaca
    27661 ttgctatccg tttctttttc tgctgctctt gtcagcatat ccacccactc acgtctaata
    27721 tcattcttcc aatcaaccaa ctcagtgagt gcctgtgtat ggttatagta aggcgagtag
    27781 tcgtatgact tatcttccaa gcgaacgcat ctacctgcct tgatgtcttt ggccaggttc
    27841 gctctcacat tactatttgt tgtaccaacg acctcagcca cttcatcata tgaggcagca
    27901 gggtgctctc tataatattc cctaattcgt tcagcttgag tcatgtttct cctccttatt
    27961 tcaacccttc aggcggttct acatcataag taaattgctt atctgaattt ctcagattca
    28021 tccgtgcaac attgtttgcc atcagctggc gctctttttg tttcatttca gcgtggtcat
    28081 ctagtttatt tactagcgac catagtccaa ttcctacgat tattaccagg taaatgtatt
    28141 ccatcatttt tctttctcct tttctttgta gattgctacg attttcttca agtctgcgat
    28201 ttcttgattc gcttcttgaa gtttttcctg tgtttcaatt agtgattgat tgaggtctaa
    28261 agcgacctct ttccagtcga gattagtttc tttgacctct tccgaaaaat agtttttgat
    28321 tcttgatagt aggttcatcc tgctgacctc attttcttgc ttgtttccat ttcttttttc
    28381 caagctttag ttccacgata ttgcaagtat tcatagaaac ctttaatcgt tacaagttgt
    28441 ccactatcca aaagatgttt ttgctgacta gggagttttt gcatttctct tcttcgctct
    28501 cctgcttgtc gttttgaaca tccaaagata cgttttaact cttcatcatt agcagagact
    28561 ttttcaatga tcacgtcttt aattctcacg atttgaactg tttccatttt tgctcctttc
    28621 gtgttataat ttagttagtt atttttgatg agcgcctgac ttcgttaggt gcttttttct
    28681 gctactcaat cttcttatcc tttcttctct cgttttctgc tataatacat acagaaagga
    28741 ggataactta tgactaagtc tgatttggga ccttatctag atgcagttac aaacgaagat
    28801 ggtactcttc taatctgcaa aacagagcaa ggtgcataca ttggcgattt caacccttca
    28861 tgcgatgaag aagattttgt gctaacttat gaagacgttt ctgtttcttt gtcttacgca
    28921 caggttcttt ctgcaactct tttgaaggtt taatcgctgg cttcaaatga tcattcatcc
    28981 aaatactaaa caaaaactga cactgtccaa ccgtcttttt tgttctagtg cttgggtgga
    29041 tttttatttg tcggaaatcc tcccacgcta acttatgtcc gtaccctttt agaattttcg
    29101 taaacaattc aaaaggtact tcaaatgtaa tcttgtcaag tccagtagat tctacataat
    29161 cttctggtaa cttaaatagt tctctgtctg tcattctttc tcctctttgg ttatataaac
    29221 agctcagtct atcaagattt tgagaaatca atttcagatt ctcactaatc gagcgtgact
    29281 ttttttgata cggcaatctc agaaatttac caccagaggt aactacctta atgatttttt
    29341 cgaggtggtc tttttcttgt ttcaagcttt caagaacgct ttccatctat gtgttcctcc
    29401 ttcttatttt tttgtttcta gtcatttacg aaattttcgt attttttacc taaaaaaata
    29461 tcatcgaatt tcacattgaa aaaaaacatg tattttttca atagctgata accgatatca
    29521 gagctatctt tttctaatct agcaattgtt tgacttgaaa cttcaaattt ttctgccaac
    29581 tctgcttgag taagtccttt gttgattctc atagcttcta aagtccactg cacgttccta
    29641 cctccttatc taaattcatc caagctgact tccaatgcat cagcgatttt gcatatatta
    29701 gtccaagaaa ggtactttac ctttccactt ttcaaatcag aaaagaaact acggttgact
    29761 ccagacatct tagataattg ataaccattc aaatttcttt cctgcattat tcggtttaat
    29821 tgttcccaca ttttacaccc ccaaaaacac tatatgttgt taaacaaata tatttaatta
    29881 acaatatgtt gtgtttttct gttatctatg ttataatcat tcttgactaa gacctctcac
    29941 cgttttagtc aaaattccaa tagaaaggag gagattttat gaaatccttt aaatattttc
    30001 gagaatcttt aacagctgaa gatatgcaag ctatctctgc taaagctaat gaagctacta
    30061 aacagattga ccatacagac ggattgcaac tggggaaggt cagtggtttg acttctgtaa
    30121 taactactat tgagttactt gagaagtatc atgaatggct tcatagctaa gacgcttaaa
    30181 ttcttctaag tctatctgaa aattgatagg ctttttttgt aaacactcaa gaaaactagt
    30241 gtttcttaaa agtttttcaa ctaactcagg gtcggccttt acaaaggtgg actctttttt
    30301 cccactatac ggatatcgtc ttggtctcat ttcctcaccc cctttcaaat atggtataat
    30361 caaaataaaa cgattggaga aatcttatga tatttcaagt gaaagtaaat tcttctgttt
    30421 ctaggcctgt aaccgttgaa gacatttgcc caaattgtaa aaaaccaacc aatccagatc
    30481 ttgtgaactc ttcttatttt tctcttggag aaaataaaac aagcttagta ttaacatgta
    30541 gatgcttagg ttgtaagcac ttttggacag aggagtttat agctacaaga tttttaatca
    30601 atgactatac cgaaaaatac gaaattgaac atatcaaagt aatccctaat cttccgagcg
    30661 atatacctat atctgacgat gtagagatag tttctccaat tggtaagcaa atctatgtcc
    30721 aagcactgaa agctgaacac gaacaactag accacattgc aggtattgga taccgtaagg
    30781 cgcttgagtt ctttgttaaa gatttctcca ttgttacaaa tcctgatgat gaagataaaa
    30841 tcattaaaat gtcattaaaa caagttattg aaaaatatat caaggatgaa gaccttaaaa
    30901 catttgcgct tgcatctgct tatatcggta acgatgaagg tcattactat agaaataatc
    30961 ctgataaagg ttttacagac ctaaagaact acctacacgg agttattcac tacatggaaa
    31021 tgaaactcaa tttccttgat gctcaagagc ttgtgaatcg ttcaaagaaa tcttagaatc
    31081 tacttcatcc aacttctcag ctatatatgt cacagtcctc aatatctcat tgagggctgt
    31141 tctttctagt tcgttcattt gtcttacctc cttttcctta agcttgattt aattataata
    31201 cgattttttc gtattgtcaa tagtttttat caaaaaaata ggattttttc gtatttttga
    31261 ttgtttatca ttcaaaaatg atatataatg taattataaa aaatacgagg taatcgtaaa
    31321 tggacgaaaa aaaacgaatg caaattattg ctgaaaatat tacacacttt agaaagcaac
    31381 gtggcatcac ccaaaaagag ttggctaaag aagttggaat tacagcaagt actatgacag
    31441 actatatgaa gttaagaagc gctccttctt ttggtgttat ccaaaaactg gctgattatt
    31501 tcggtgttaa aaaatcagat atagatacta cttttaaaga agaatccacc aactcactgc
    31561 cagacgctcc agattcgctc acacagcaga taatggataa ggtagtgcaa ttaatcactc
    31621 caaacaaaaa aatcgttctt cggacgtctg aagagcttct ggagagtcaa aaaaacgaag
    31681 aagaaacgaa ggtaaacgaa gtatcggaga acatcatcag actggacgac tacagacaga
    31741 ctacttaccg acgtgttact ggggttgtct ctgctggtag tggttcgata caggacgacg
    31801 atttagatat ggaggtttcg ttctatgagg atgaaatccc agacgactac gacgctatcg
    31861 cttatgtcgt cggcaactct atggagccaa agataaagaa tggcgactat ctttttataa
    31921 agaataccca acaggttgat tataacacta tcggcatctt ccaagtagac ggcgctaact
    31981 atgttaagaa actgcgtcag ggatatctgg aaagcttgaa tccagattat gaggatatac
    32041 acctagacga aagcaacgat atccgaacta ttgggaaagt cgtgagtgtg tatagagaga
    32101 aataaaaaag aaagtaggta attacaatgg aattaaaaga aattatagaa aatataaaaa
    32161 aagaaatccc tgttttggat tcttctaccg actattggct agtacgtgct aactctggag
    32221 aatattacac ggattttaat ctaaatggct atataggtat cggatggaat gaaatcaccc
    32281 tcgaagatat tagacgagca gataataact cgaatgtatt aaaagaaatt ttaaaagaga
    32341 aattaacatt tcaagatgac tcagaaccat ctgaaaacaa atatggtatc accgcaggtc
    32401 aactccttcg ttttgtaaat aacattaaaa gaaatgatat agttgttgtg ccatccgaag
    32461 ggtctgaaag atttttagtt ggtaaagtaa ccggaccgct ctatgaactt aatcaatctc
    32521 aacttgagga atataaaagc gaagagttga cacataatcg gtcagatttt gcaaaaaggt
    32581 ggaaagtcta ttggttggga tggttcaatc gttccgacgc agacagcgca ttgtataaaa
    32641 tgatctattc tcatgcaaca ctatcaaata taaatgatta taaaccgttc attaaccgcg
    32701 cactttttcc ttgctatatt gaagacgaaa agctatatat tagctaccat gtaacagaag
    32761 aaaaagatat tcaaggggta tatttaggtc aatttgttta tcaatattct ctattaacaa
    32821 ggttgctttt ccctgaaaca cgagtagatt caaaaataaa cgtacaatct gagggtataa
    32881 tagaacttat tacacacact gtaaattacg gacttataat ttcagcgata cttagtggag
    32941 caattgttct gacaagtggg ggaaaattaa agtttatggg attagaacta gaagttccag
    33001 gattaataaa tacatatcaa gagtatcaaa aaaataaact cgaacggatt aagcaagcaa
    33061 aagaactagc tgacgaactc ggtgtaccaa tatctgaact aggcattcgt attccaagaa
    33121 aactaacaac agctattgaa agccaaaaga atgtaaaact tgcttccagt aatccgccag
    33181 agaaatctgg agaataaaaa aagtctaaca tcagttagac tcgaagaaaa tgaatttctt
    33241 tagttttaat gagataagca tagctatcgc taaggaaaga taatcgtttg tgataaaaat
    33301 tgtggttatt gagaaaaata tcttgaaaat caagagaaat aaaaatatag atacaataaa
    33361 attttttaac tttgttttca acatattttt tctccttatt cttttgaaac aattataaca
    33421 caattatctg ttaaagttaa ataattctaa aaaatcccca cactctccat cgccaaactt
    33481 tgagtgtgag gatatcctgg atagtaaaag gcattaaaaa gccctcttta ctatacccat
    33541 tttatcaaaa agtgaggtta aaatcaatgt ggatggaaga attaccaaac ggcaaatata
    33601 aattttttga gcgatacaaa gatccatata ctgagaaatt aaaaaaagtt tcagtaacca
    33661 tggagaagaa aactccccag gcaagaaatc aagctgctat cttgttgcaa gagaagataa
    33721 ataaaaaact tagcacaaaa caagtagaaa gcattacatt tgaagaaatc tataaccttt
    33781 tttataaatc atgggcgcaa acagtaaagg aatcaacaaa acataattgt aaatcagttg
    33841 ataagaagat gaaggaagtc ataccatccg ataccatact tgctaatctt gacaggcgtt
    33901 ttcttcaaga ggctattgaa aaaattattg aaagcaacgg atatattaca gctaaaaaag
    33961 tacggcatag gctcagaggt atctttaatt acgctgttca atactcttac attgaaaaca
    34021 acgaggtcga ttatactacg attcctcaaa aaccaaagac tttagaagaa ctggaaaaaa
    34081 agcgtaacaa ctttctcacc atgaaagaaa taaaagcact tgtcgatgtc cttaatcgtc
    34141 gagaatatca ccaaaagtac gctgatatgg ttcttgtgct gacattaact ggtatgagat
    34201 atggtgagtt aactgcctta caactgaaga atatagactt cgaaaacaac aaaattgaga
    34261 tcacaggtaa ttttgattca gtaaacaaaa tcaagacgct accaaagact acaaattcaa
    34321 tacggacaat caaagtatca gagagtgtca tagaagctat tcaaagacaa atagtacgac
    34381 ttagcgaacg tttccagcca ttgtcaagcg atgattatat tttctgtttt gaaaaatgga
    34441 atcaacctac aacaatagct tgcttcatac agatattaaa aaaatatgga aaacaggcca
    34501 aaatagaaaa aaacttatct agccatattt ttaggcattc tcatatttcg tttttagcag
    34561 agtctggcct cccaataaaa tcaataatgg atcgagttgg gcactcaaat gcaaaaatga
    34621 ctttggaaat ctattctcat actactgagg atatggagga taaactggtc aataaattag
    34681 atactatttt ttaattctgc cccttggttg cccctttttg atttcataac acaacaaaac
    34741 cccttgaaga tattgataat tcaaggggtt gcttt
//
LOCUS       DAVAGB010000017        34252 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVAGB010000017 DAVAGB010000000
VERSION     DAVAGB010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34252
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.017"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(296..1144)
                     /gene="dprA"
                     /locus_tag="VQO19_000963"
     CDS             complement(296..1144)
                     /gene="dprA"
                     /locus_tag="VQO19_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HET1349250.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            complement(1250..1939)
                     /locus_tag="VQO19_000964"
     CDS             complement(1250..1939)
                     /locus_tag="VQO19_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HET1349251.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            complement(1951..2829)
                     /locus_tag="VQO19_000965"
     CDS             complement(1951..2829)
                     /locus_tag="VQO19_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET1349252.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2819..3688)
                     /gene="licA"
                     /locus_tag="VQO19_000966"
     CDS             complement(2819..3688)
                     /gene="licA"
                     /locus_tag="VQO19_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HET1349253.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            complement(3705..4727)
                     /locus_tag="VQO19_000967"
     CDS             complement(3705..4727)
                     /locus_tag="VQO19_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET1349254.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4732..5439)
                     /locus_tag="VQO19_000968"
     CDS             complement(4732..5439)
                     /locus_tag="VQO19_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HET1349255.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFVDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5775..7262
                     /gene="tacF"
                     /locus_tag="VQO19_000969"
     CDS             5775..7262
                     /gene="tacF"
                     /locus_tag="VQO19_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HET1349256.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7272..8075
                     /locus_tag="VQO19_000970"
     CDS             7272..8075
                     /locus_tag="VQO19_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET1349257.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8077..8886
                     /locus_tag="VQO19_000971"
     CDS             8077..8886
                     /locus_tag="VQO19_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET1349258.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKYDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(9161..12337)
                     /gene="carB"
                     /locus_tag="VQO19_000972"
     CDS             complement(9161..12337)
                     /gene="carB"
                     /locus_tag="VQO19_000972"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HET1349259.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(12650..13729)
                     /gene="carA"
                     /locus_tag="VQO19_000973"
     CDS             complement(12650..13729)
                     /gene="carA"
                     /locus_tag="VQO19_000973"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HET1349260.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            complement(13779..14702)
                     /locus_tag="VQO19_000974"
     CDS             complement(13779..14702)
                     /locus_tag="VQO19_000974"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HET1349261.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            complement(14721..15242)
                     /gene="pyrR"
                     /locus_tag="VQO19_000975"
     CDS             complement(14721..15242)
                     /gene="pyrR"
                     /locus_tag="VQO19_000975"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HET1349262.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            complement(15453..16082)
                     /gene="nth"
                     /locus_tag="VQO19_000976"
     CDS             complement(15453..16082)
                     /gene="nth"
                     /locus_tag="VQO19_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HET1349263.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            complement(16082..16624)
                     /locus_tag="VQO19_000977"
     CDS             complement(16082..16624)
                     /locus_tag="VQO19_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HET1349264.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENEALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            16794..17111
                     /locus_tag="VQO19_000978"
     CDS             16794..17111
                     /locus_tag="VQO19_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET1349265.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYEHVKHVLSLYGPV
                     FGF"
     gene            17350..18909
                     /locus_tag="VQO19_000979"
     CDS             17350..18909
                     /locus_tag="VQO19_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET1349266.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQKIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKTAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEICSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(19058..19957)
                     /gene="htpX"
                     /locus_tag="VQO19_000980"
     CDS             complement(19058..19957)
                     /gene="htpX"
                     /locus_tag="VQO19_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HET1349267.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALVSAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(19959..20519)
                     /locus_tag="VQO19_000981"
     CDS             complement(19959..20519)
                     /locus_tag="VQO19_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HET1349268.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            20613..21326
                     /gene="rsmG"
                     /locus_tag="VQO19_000982"
     CDS             20613..21326
                     /gene="rsmG"
                     /locus_tag="VQO19_000982"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HET1349269.1"
                     /translation="MKPETFYNLLAEQNLPLSNQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            21678..22961
                     /locus_tag="VQO19_000983"
     CDS             21678..22961
                     /locus_tag="VQO19_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HET1349270.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(23156..24727)
                     /gene="ffh"
                     /locus_tag="VQO19_000984"
     CDS             complement(23156..24727)
                     /gene="ffh"
                     /locus_tag="VQO19_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HET1349271.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(24739..25071)
                     /locus_tag="VQO19_000985"
     CDS             complement(24739..25071)
                     /locus_tag="VQO19_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HET1349272.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            complement(25162..25539)
                     /locus_tag="VQO19_000986"
     CDS             complement(25162..25539)
                     /locus_tag="VQO19_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HET1349273.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFTIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            25611..26915
                     /locus_tag="VQO19_000987"
     CDS             25611..26915
                     /locus_tag="VQO19_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET1349274.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSISFSQEDQDQLASMRKLAE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            26928..27734
                     /gene="yidA"
                     /locus_tag="VQO19_000988"
     CDS             26928..27734
                     /gene="yidA"
                     /locus_tag="VQO19_000988"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HET1349275.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            27777..28775
                     /locus_tag="VQO19_000989"
     CDS             27777..28775
                     /locus_tag="VQO19_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HET1349276.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNELECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLTVVELKTILSKHN
                     LATSGKKAELITRIINNVNIDNLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDITMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(28942..29013)
                     /locus_tag="VQO19_000990"
     tRNA            complement(28942..29013)
                     /locus_tag="VQO19_000990"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(28978..28980),aa:Arg,seq:cct)
     gene            complement(29055..29402)
                     /gene="rplS"
                     /locus_tag="VQO19_000991"
     CDS             complement(29055..29402)
                     /gene="rplS"
                     /locus_tag="VQO19_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HET1349277.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(29521..29850)
                     /gene="crcB"
                     /locus_tag="VQO19_000992"
     CDS             complement(29521..29850)
                     /gene="crcB"
                     /locus_tag="VQO19_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET1349278.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(29844..30218)
                     /gene="crcB"
                     /locus_tag="VQO19_000993"
     CDS             complement(29844..30218)
                     /gene="crcB"
                     /locus_tag="VQO19_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET1349279.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            complement(30215..30481)
                     /locus_tag="VQO19_000994"
     CDS             complement(30215..30481)
                     /locus_tag="VQO19_000994"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HET1349280.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREAVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(30597..31040)
                     /locus_tag="VQO19_000995"
     CDS             complement(30597..31040)
                     /locus_tag="VQO19_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HET1349281.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            31144..32079
                     /locus_tag="VQO19_000996"
     CDS             31144..32079
                     /locus_tag="VQO19_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HET1349282.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            32133..32417
                     /locus_tag="VQO19_000997"
     CDS             32133..32417
                     /locus_tag="VQO19_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HET1349283.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(32474..32962)
                     /locus_tag="VQO19_000998"
     CDS             complement(32474..32962)
                     /locus_tag="VQO19_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HET1349284.1"
                     /translation="MSSYFVKITDASKAVKNGDQAEVQKLVTKMASDFERVENKDSEV
                     GKIVKEKLALSGDITEAKLTEISSALLAFEKEQNPVDLDAEKEKLVNRLSPRFETLEQ
                     AIASKDLEKVREAFKKMNSTWTINESVVRDNSTAHYGRVETAISFLPSSMETEPTDES
                     GT"
     gene            complement(33062..33733)
                     /locus_tag="VQO19_000999"
                     /pseudo
     CDS             complement(33062..33733)
                     /locus_tag="VQO19_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259617.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            complement(33736..34195)
                     /locus_tag="VQO19_001000"
                     /pseudo
     CDS             complement(33736..34195)
                     /locus_tag="VQO19_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
BASE COUNT        10414 a         7362 c         6245 g        10231 t
ORIGIN      
        1 tcactatact ttcccttata ctcaatgaaa atcaaagcac tgctttgagg ttgtagataa
       61 gactgacgaa gtcagctcaa aatactgttt tgaggttgca gatggaagct gacgtagttt
      121 gaagagattt tcgaagagta ttatatgaga aaaatcctct actctactaa tccacttaga
      181 aaaaacgcat attatcaagt gttaaaaact tgctaatatg cgttttatta tggaaatgtt
      241 gggttcattt tctcttaaaa ttgatttttt cttagaattc tagcttaggt catttttaaa
      301 attcaaattc cgcaagaaca tcttgcccac tggtgaccaa ttttgctcct tcttgaatca
      361 aatgatggca accgtctgat agtccatcta aaatgctacc aggaatagca aagacatcgc
      421 gtccttcttc cattgctcgc tcacacgtaa tgagactacc tgaacgcatc ttagcctctg
      481 ctacaatcac accacgacaa agtccagcaa tgatgcgatt acgggcagga aaatgaaatt
      541 tcagaggttg ttcgccaggt ccatattcac ttagaaccag atggtcattg ccgatgtagt
      601 cttgcaagcg tttattggct ttaggataaa acacatccag tcctgttcca atcactgcaa
      661 tggtttttcc gccattctga agagctgcca tatgagctgc tgtgtcaatg cccttggcca
      721 gaccactgac aataaccagt tcattttcca agccttgaat gactttttca actgacttag
      781 ctccctgttt gctacaagca cgactgccca cgaccgctac cttcgggaat ttcaggaggt
      841 caagatttcc cttgtaaaat aaaagtacag gcgcatcata tatttcactc aaatcccaag
      901 gataacagtc atctaaaata gagaaagatg gaaatttttg aaactctttc gacaaatgcg
      961 catcgtctat ctgaaaataa cgttccataa aaacggctgg attacggcaa cctgatatat
     1021 ctgcaatatc acccaacaaa agctcctgat caacattttc accgtattct agcactttca
     1081 aaatctgttg attggtcaaa cctgattttt ttaacttata gatttcatag tttgtgattt
     1141 tcataaataa ctccatttct ttttctactc atctatctat tcgtaaaagt tcgtaaaagt
     1201 tcgtaaaaaa tcaaaaaaca tccgactatt ttgccagatg ttggaatctt taattttcgt
     1261 ttttaagaat ttcttctaat ttacgatagt cttggacact atcgatctca taaatgctat
     1321 tgccttctaa ttcttcaaca tagacatcta gctctttgat attatcctta accatattgt
     1381 cccaatagag atcaacaaat tcaccacttg cataagcctt gtcgataaag ctgacaatct
     1441 tttctgcagt tggagcatcc cagaaggata caccactaag gatgcgacct gccttgctat
     1501 caacaataat gtcttgaacc ttgtagtcat ctccatagac caagaaccat tcgttggtac
     1561 aatcttcacg ataaacacta aaataagtcg aacgtgtcaa atcattgcgg aacatatttt
     1621 taaagagata attgtcagca tcaataacat agctgttggc caattcttct tttacaagat
     1681 agagagagta aaagttattg tagtcagcgt atttatcatt gaaaacgagg cgaacaccgt
     1741 atttttcttt taagtaatcg aattgttctt taagataacc aacaatgatg atgatgtcat
     1801 tgattccttt ttctttgaga aactcaattt ggtattcaat caaaggtttt tgattaacct
     1861 gaaccaaggc tttaggggta ttttcagtca taggacgcaa gcgagttccc aatcccgctg
     1921 ctaagataat ggctttcaca cgaatctcct ttattcttta ataataatat aaactccagc
     1981 aatgacgaca agtgacgtca taatggtcag catatctagc ggtgcaccca aaaaaacaac
     2041 tgcaaacaag accgtccata ctacatagct cacgttcaag cctgtagcct tggctggttg
     2101 caagcgattg atagcgatat aataagccaa gtaggaaatc atatcaaagg ctgcaaaaac
     2161 aatcatgaga cctagcaatt gtccattggc tactgcagta aatgactgat gagagaagag
     2221 cacaatcaca agataggaca agaacgaagt cacttgacgg attaagaggg cttcgatttc
     2281 actcagttca ctttccatag caaaggagct aagaacactc tcacttcccc atgcaatagc
     2341 acaaaccaaa gcacagagaa tcccaatgta gaaggaatta acctgttcaa ccttataggt
     2401 ctgggcaata atccctccaa taatcaagac aatcccaaat acagtatttt tcgaaatctt
     2461 gtgcttcaaa aagaagaaag ccaatagaac tgaaatcgca gggtaaatag ccgatacaga
     2521 tgaagctaaa gaacttccga tatacttaac tgcataaaga ttggcctgca taccgatagg
     2581 gcctgctagc aaggctccga tgataacact gacattgcga atatttaaga aaattgagag
     2641 gcgaactttc ccttctttta ccaagagaaa agctagtaag ataaagatgc tcaaaaaatc
     2701 atgagctgca gccaccacaa agggtgacaa atctgtaaaa atcgaaaaga tataagcact
     2761 aaccgttaga cccaagcccc agaaaatacc tgagagaagg ccaaaaggaa ctccgttttt
     2821 acttttcatc tgaacctcca taagaagcca aacctttaac agctctttgg taacgattca
     2881 caccatagtc accaaaatct tcaccttgct cttccttata gacagtccat agactccaaa
     2941 tagtatcttg taaaatttta taaatagcaa tcttttcatg agaaaccggt gtttggtcac
     3001 tctcatagtg agataagaaa gtttcttcct cttgggaagt gaattcagac tctaaaaaga
     3061 gggcagccaa atcccacatt ggatcattca ttgatgaata ttcccagtca atcaaataaa
     3121 gtcgtccttg aggtgattcg ataaagtttt caggcaccaa atcgatatga caagattttc
     3181 tgtcaacacc taagtcagcc agtcttttct ctaaggagaa gactgcattt ctaacagatt
     3241 catagttggc ataaggaatt tgttcttcaa tcaaggattc gtattttttg atttcttcaa
     3301 aaggagcaaa ttctcctctt aattccttag cagacgtatg aatagtttgt aatattggag
     3361 caattttgtc gaacttggtc ttgattgacg ttgaatcaag cgtaatcgca gattcgatat
     3421 actcatttac tttgatacca gcttcaatat caaaaagata attttttaca tctaagccta
     3481 aatcctttag tagttcaaga ttgtactttt catcttgtcg attgataagc ttttctgtcc
     3541 ctttaccaaa gaatttaaca atgtattgct tatttgttgt tttggccaaa tagttttgat
     3601 tggtcattcc acccagttgt tcaacactga ggacttcctc ttcttgacta agtaaggaag
     3661 aaattttttc tttaatgatt ttctccacaa ttaacctcca gtacttatac ttcccactta
     3721 aacactgttt taaaggctgt gtttaaatcg gttgcaaaga cacgatgaat atctttaatt
     3781 tctcttacag gttcttctag ataaaggata tttttaagac gattggcaaa tttcttgact
     3841 tccatcattt ggatagcatt tttaaaatca atgcgaccag aacgagatga cccaaccaaa
     3901 atcaagccct tttctaaggc atcgcgagta ttgagattga ctttatattc gctaactccc
     3961 atcatgagaa tcgttccctg aggacgaatg tagcgaatca agtcattaat agctggtcca
     4021 gtaccatcac caccacaaca ttcaaaagca tggtcaaagg ccaactcttc aggaatatta
     4081 tccgtaatat agcattcttt ggcaaatgag aagagttcca acttttccca atgacgacca
     4141 ataaccacaa tctctgattc tggcaaagta tagttgataa tattggcaac cacaaaagct
     4201 aaacttccat ctccaataac ggcgatccgc tcccgcttgc tatgagcaag agtcaataga
     4261 cgattcatag cgtgcatgcc cacactgaca aactctgtaa tggctgcaac cgtatcttca
     4321 atagcatcat aagccaccac acgatcttta gggagagaaa caaactctct cataaagcca
     4381 tcaaatccac tagacaagaa atgggtccct gtcatgtagt tttcatagaa ttcttcatca
     4441 ctctgcatag gagactgatt gggaatcatg acaacttttt gaccaacctc gtaggttccg
     4501 gtcgggtcag aaatgacggt tccacatgac tcgtgaatca ttgccattgg aagcttttta
     4561 ttcaaaatct tgggatcacg ttttccctga tagtaacgct gatccgcatg acagacagcc
     4621 atgtagttgg gacggataag gatatgattc tcttggtcaa tagcctcttc ctgatatttg
     4681 acattgataa acttaggctt agttagttga taaatttgat taatcatttt actagtcttt
     4741 ctcaatcata ctttttgcaa tcttcaaatc tgttacggtt gtaatcttca gatttgagta
     4801 ttcacctttg gccaaggcca catcttttcc tttgatcaca aagattttac atgcatctgt
     4861 caagatttcc ttctcttcat cagaaagaga tccataaagg tccacgaagt ccttgcaacg
     4921 gaatgtttga ggtgtttgtc cttgataaag gtgagcacga tttggaatat ctgtaataaa
     4981 ttgaccattg gtactttcaa cgatagtatc aactgcttct accactgtgt ccactgcgtc
     5041 atgattttgg gcaagttgga tattgtcctg aatcatgcga agtgtaataa atggacgaac
     5101 agaatcgtgg gtaacaacga tatcctctgg agtaagcgga cgataagcat caatggcttc
     5161 aatgattttc ttaatacttg tattgcggtc agcaccaccc tttgtaatga tgatacgttc
     5221 cttataaaga ggaagatatt tatctacaag atcttctgca tgagaaaccc agtctccatg
     5281 aacaccaact acaatttttt caatacttgg ctccaagaca aatttttcaa ttgtatgaat
     5341 caaaataggt cgatcaccta gctctaaaaa ttgttttggc aagttactga tccccatgcg
     5401 tgtgccagtt ccaccggcaa gaattcctgc ataaatcatc tattttctcc tttgtcttac
     5461 taaaaaaact tattctctct attataccac aatctagtcc tatcataaaa gaaatactgg
     5521 tcctcccctt ctagaatagg agaattatgc agttctatta ttcaaagaaa ctagtccatt
     5581 tctagtaatg actaggaatt ctgtagcaat tactaataaa tggctgcgaa attttagagt
     5641 ccttcagaat aatatacttt ccttaaagaa aacttaaaac ttaagatttg aaacttcaaa
     5701 gtgattactt gacttactgc ccttcatttc ttattagcta actttatgat ataatgaaaa
     5761 acgaggtaaa ttgaatgaaa agtataaaat taaatgctct atcttacatg ggaattcgtg
     5821 tcttgaatat tatttttccc atcctaactg gaacctatgt cgcgcgtgtc ttggaccgaa
     5881 ctgactatgg ttacttcaac tcagtcgaca ctattttgtc atttttcttg ccctttgcaa
     5941 cttatggtgt ctataactac ggtttaaggg ctatcagtaa tgtcaaggat aacaaaaaag
     6001 atcttaacag aaccttttct agtctttttt atttgtgcat cgcttgtacg attttgacca
     6061 ctgctgtcta tatcctagcc tatcctctct tctttattga taatccaatc gtcaaaaagg
     6121 tctaccttgt tatggggatt caactcattg cccagatttt ttcaatcgaa tgggtcaatg
     6181 aagctctgga aaattacagt tttctctttt acaaaactgc cttcatccgt atcctgatgc
     6241 tggtctctat tttcttattt gttaaaaatg aacacgatat tgttgtctat acacttgtga
     6301 tgagtttatc gacgctgatt aactacctga ttagttattt ttggattaaa agagacatca
     6361 aacttgttaa gattcaccta agtgatttta aaccactctt tctccctctg acagccatgt
     6421 tagtctttgc caatgccaat atgctcttca cttttttaga tcgcctcttc ctcgttaaaa
     6481 cagggattga tgtcaacgtt agttactata ccatagctca gcgaattgtg accgttatag
     6541 ctggggttgt aacaggtgca attggagtga gtgtgcctcg tctcagttac tatctgggga
     6601 aaggagacaa agaagcctat gtttctctgg ttaatagagg tagtcgaatc tttaacttct
     6661 ttatcattcc actgagtttt ggactcatgg ttttaggacc aaatgccatc ctactttacg
     6721 gtagtgaaaa atatatcgga ggcggcatct tgacctctct cttcgctttt cgtacgatta
     6781 tcctggcctt agataccatt cttggttccc aaattctctt taccaatggc tatgaaaaac
     6841 gtatcacagt ctatacagtc tttgctgggc tactcaattt gggcttgaat agtctcctct
     6901 ttttcaacca tatcgtggct cctgaatact acttactgac aactatgtta tcagagactt
     6961 ctctacttgt tttctatatc attttcatcc atagaaaaca actcatccac ttgggacata
     7021 tctttagcta tactgttcga tactctctct tttcactttc ctttgtagca atttatttcc
     7081 tgattaattt cgtgtatcct gtggatatgg tcattaattt gccatttttg attaatactg
     7141 gtttgattgt cttgctatca gctatctctt atattagtct acttgtcttc acaaaagata
     7201 gcattttcta tgaattttta aaccatgtcc tagccttaaa aaataaattt aaaaaatcat
     7261 aggagtttaa aatgaaacaa ctaaccgttg aagatgccaa acaaattgaa ttagaaattt
     7321 tggattatat tgatactctc tgtaaaaagc acaatatcaa ctatattatt aactacggta
     7381 ctctgattgg ggcggttcga catgagggct ttatcccttg ggacgacgat attgatttat
     7441 ccatgcctag agaagactac caacgattta ttaacatttt tcaaaaggaa aaaagcaagt
     7501 ataagctcct atccttagaa actgataaga actactttaa caactttatc aagataaccg
     7561 acagtacgac taaaattatt gatactcgaa atacaaaaac ctatgagtct ggtatcttta
     7621 tcgatatttt ccctatagat cgctttgatg atcctaaggt cattgatact tgttataaac
     7681 tggaaagctt caaactgctg tctttcagta aacataaaaa tattgtctat aaggatagcc
     7741 ttttaaaaga ttggatacga acagccttct ggttactcct tcgaccggtt tctcctcgtt
     7801 attttgcaaa taaaatcgag aaagaaattc aaaaatatag tcgtgaaaat gggcaatata
     7861 tggcttttat cccttcaaaa tttaaggaaa aggaagtctt cccaagtggt acctttgata
     7921 aaacaatcga tttacccttt gagaatttaa gccttcctgc acctgaaaaa tttgatacta
     7981 ttttgacaca attttatgga gattatatga ccctaccacc agaagaaaaa cgcttctaca
     8041 gtcatgaatt tcacgcttat aaattggagg attaggatgc aatatttaga aaaaaaagaa
     8101 attaaagaaa ttcaactagc cctgctggac tatattgatg agacttgtaa gaaatatgat
     8161 attccttatt ttctcagtta tggaaccatg cttggagcca tccgccacaa aggtatgatt
     8221 ccttgggatg atgatattga tatttccctt tatcgtgagg attatgagcg tttactgaag
     8281 attattgaag aagaaaatca ccctcgctac aaggttcttt cctacgatac atcttcttgg
     8341 tacttccata atttcgcatc gattttggac acttctactg ttatagaaga ccatgttaag
     8401 tacaagcgtc atgataccag ccttttcatc gatgtcttcc caattgatcg atttacagac
     8461 ttgagcattg tcgacaagag ctataagtat gtggctcttc gtcaactagc ttatatcaaa
     8521 aaatcacgag cagttcacgg tgatagcaaa ctaaaagatt ttcttagatt atgtagctgg
     8581 tacgctctcc gatttgtcaa tcctcgctac ttttacaaga aaattgatca actagtcaaa
     8641 aatgctgtaa ccaacactcc tcaatatgaa ggaggagttg ggatcggtaa ggaagggatg
     8701 aaagaaatct tcccagttga tacctttaaa gaactgattt taactgagtt tgagggccgt
     8761 atgttgcctg ttcccaaaaa atatgaccaa tttttaaccc agatgtatgg cgattatatg
     8821 acaccaccat caaaagaaat gcaagagtgg tatagtcata gcattaaagc ttatcgcaaa
     8881 aactgattga ggggtattat acaaactact aagatagagg ttattcaaaa acataatttt
     8941 agtagaaaat gaaatacata ttcccacaat aaaacgcatc atatcaaggt ttttcaaaaa
     9001 ccttgatatg atgcgtttta taattttaaa gacttttttc tatagtagat tgaaataaga
     9061 tgcgaacgaa tcaattagaa aattcaaatt aatttctaga aatattttag tatccctgtg
     9121 tactgttcta aattcagtct gctatacctt atttttctat ttaaatcgct tctgtaacaa
     9181 agctacgact ttcaagtacc ttaagcatgg cattagctgt atctagcgct gtgaagaggg
     9241 gcaccccgtg ttcaatggct gaacgacgaa tttgctcacc atcttcgtca gcagttcgtt
     9301 ttgttcctac tgtgttaatg atagcttgaa ttcttccttt gcgtacaaaa cttgggatat
     9361 ccttatcatc atcaccaatc ttaccaacag gttgggcttg caagccatga ctagcaaaga
     9421 aggctgctgt cccttctgtc gcaaggattc cataaccaat gttttggaaa cgacgagcca
     9481 agttcaaggc ttcttctttg gcatcatcag cgatggtaaa gacgacatta ccaaaagttg
     9541 gcaagtgtag ataagaagct tcaaaggctt tatagagagc tttttccaaa gtagcatcag
     9601 aacccataac ttcacctgtt gacttcattt caggaccgag caagctgtct accttagcta
     9661 gtttggtaaa ggagaagaca ggtgccttga tatgaacacg ggtgctttca gggtaaagtc
     9721 cattttggta gccaagttct gataaacttt gaccaagaat gagcttggtc gctacttgag
     9781 ccataggaat attggttacc ttagatagga atggaactgt acggctggca cgtggattga
     9841 cctcaataac gtagactttt tcatccttga taacaaactg gatgttcatc attccaaggc
     9901 agtgaagacc gattgctaag cgtttggtgt agtctgcgat ggtctcctga accttttgcg
     9961 acaaggtttg tggtgggtaa acagccattg agtcacctga gtggacacca gcacgttcga
    10021 tatgctccat aataccagga atgagtacat ttttaccatc tgaaatggca tcaacttcgc
    10081 actcttgccc aacgatgtaa gagtcgacaa gaactgggtg gtctggacta gccttaacag
    10141 cagttcgcat gtaagaacga aggtcttctt cgttttcaac gatttccatg gcacgtccac
    10201 caagtacata agatgggcgg acaagaactg ggaagccaat cttacgagct gcaagagctg
    10261 cttcttcttc attggtagcc gtttgtcctg gtggctgtgg aatatccaat tctttgagag
    10321 cttgctcgaa gaggtcacgg tcttcggcac ggtctaggtc agcaacctgt gtaccaagga
    10381 tggtcacacc tgcttttgcc aatggctccg caaggttgat ggctgtttga ccaccgaact
    10441 gaacgataac tccctttggt tgttccaagt caatgacgtt cataacatct tcgaatgtca
    10501 atggctcaaa gtaaagctta tctgatacag agaagtctgt tgaaacggtc tctgggtttg
    10561 agttcatgat aatagcttca taaccagctg cctggatagc cttaacagag tgaacggttg
    10621 cgtagtcaaa ctcaacccct tgaccgatac ggattggacc tgaacctagg acaagtacag
    10681 attctttatc agatctgata gattcatttt cccaaccata ggttgaatag aaatatggcg
    10741 tttcagagtc gaactctgcc gcacaagtgt ctaccatctt ataaactggg acaatcttgt
    10801 tttccaaacg aagttggcga acttgatcat cagtcgttcc ccagagttca gcaatcttac
    10861 ggtctgaaaa accattaagt ttggctgttt tcaaaacttc tagatcttgt ggatgagcac
    10921 ccaattcttg ctcaatttca aagatatgca agagtttatc aagatagaag atatcaattt
    10981 ttgtaagctc tgcaatttct tcaggtgtgt aaccacggcg aatggcttct gacacataga
    11041 agagacggtc atcttgggct ttgacaacct tttcaatcaa ggcatcatca gaaactgctg
    11101 caagttcagg tatttcattg tggtgcaccc caatttcaag ggagcggcag gccttgagaa
    11161 gagattcctc gatgttacga ccgattgcca tgacttctcc agtcgccttc atttgtgtac
    11221 cgagacggcg ttcacccttt tcaaacttgt caaatgggaa acgtggaatc ttagcaacta
    11281 cgtagtcaag ggctggttca aacatggcat aggttgaacc tgtaactggg tttataacct
    11341 catccaaggt caaacctact gcaatcttgg cagccaactt agcaatcgga tatcctgtcg
    11401 ctttagaagc aagggctgac gaacgtgata cacgagggtt tacttcgata acataatact
    11461 tgaagctgtt aggatcaaga gctagctgaa cattacatcc accttcaatc ttgagggcac
    11521 gaataatgct caagctcgca tcacgaagca tttggttttc atagtctgac atggtttgcg
    11581 caggggcaaa tacaatggaa tcccctgtgt gaatcccaac tgggtcaaag ttttccatgt
    11641 tacaaacaac caaggcattg tcagctgagt cacgcatcac ttcgtattca atttccttga
    11701 aaccggcaat cgaacgctca atcaaacatt gggtaacagg tgacaatttc aaaccatttt
    11761 cagtgatttc acgcaattct ttctcgttgg cacacatacc accaccagta ccaccaaggg
    11821 taaaggctgg acgaacgatg actgggtagc caattgtcgc tgcaaaggca actgcttctt
    11881 ctactgtgtt aacaatttca gattctggaa tgggttgttc aagctcttcc atcaattgtt
    11941 taaagagatc acggtcctcc gcttggtcaa tggcagataa tttggtaccc agaagttcaa
    12001 cgccaagctc gtctaggata ccatttttag ataattccat ggccatgttg agacctgtct
    12061 gaccaccgag tgttggtagc aaggcatctg gaccttcctt acgaagaata cgtgtcacaa
    12121 actcaagtgt aatcggttca atgtaaacct tgtcagcaat ttccttgtcc gtcatgatgg
    12181 ttgcaggatt tgagttaacc aaaacaacct cataaccttc ctctttcaac gacaagcaag
    12241 cctgagtccc agcgtagtca aactcagcag cctgaccaat aataatcgga ccagaaccaa
    12301 tcaccataat tttttgaata tcagtacgtt taggcatata taagatatta agggtgtcaa
    12361 gcggacaaag ctaaaatagg agttatgacg aagaactgtc agttctagga ataactatct
    12421 ttttagcacc gtccgtagcc cgtattcagt tcagcaaata cggagctccc ttctcctttc
    12481 tattcgtcgc ctctcagggc gacattaaat aagatacaaa ggacgaatag aaagcgattg
    12541 aattttagga aatcaaggaa ggattgacaa tccaagttgg tttctctaca ttctgagctt
    12601 tccgtccgtg ttcagttaca taaattctcc gacgagcttt tactcgttct tagtttgatt
    12661 gtttaaaaac ttccatcatc tcgataaact cgtcaaatag gtagctagcg tcgtgtggcc
    12721 caggagctgc atctgggtgg tattgaacag agaaagcagg ttggtatctg tggcgcacac
    12781 cttccactga cttgtcattg atttcttcgt gggtaataat caagtgctct ggcaaatcct
    12841 cgcggctgac tgcataacca tggttctggc tggtgaagtc tactcgtcct gttgcgattt
    12901 cacgtaccgc atggttgaat ccacggtggc caaacttcat cttataggtc ttagccccgt
    12961 ttgccattgc aaagagttgg tgtcccatac aaataccaaa gattggaatt tttccttgta
    13021 caccgcgaat catgtcgagt gcttgtggaa cgtcttctgg gttacctgga ccatttgaca
    13081 acataactcc gtcaggattg agatggagaa tttcttcagc cgttgtcgaa taaggaacaa
    13141 ctgtcacgtt acagttgcgt ttagaaagtt cacgtaggat tgagtgcttg agaccaaagt
    13201 ccactagcac cacgctcaaa ccaactcctg gagctggata agacgtttta gtagaaacct
    13261 gtttgatatt gtctgtcggt aaaactgttg cttggagctg gtccgtcaca tggtccatac
    13321 tgtccccaac atgggtcaag gttgcacgca tagtaccatg cttacggata atcttggtaa
    13381 gagcacgcgt atcaattcct gaaatccctg gaattttctt ggctttcaaa aattcatcca
    13441 aggtcatttg gttgcgccag ttgctagctc tacgcgcttc ttcaaaaaca acgactccct
    13501 tacaagttgg aataatggat tcataatcat cacgattaat accataattt cctaccaaag
    13561 gataagtaaa ggtcaagatt tgtccattat aagactggtc tgtaatggat tcttggtagc
    13621 cggtcatccc tgtattaaag acgatttcgc ctgttacatc aatatctgct ccgaaggcct
    13681 tgccttcaaa aactgtgcca tcttctaata ctagaattct ttttgtcata ttttcacctc
    13741 tcgtggacgc tcactggcgt cttttaacgt cttgtgtttt agttggcgtt tctactcgct
    13801 agtacggatt ctaagattgc cattcgaaca aagacaccat tggtcatttg ttggacaatc
    13861 cgtgattttg gtgcttcaac caagtggtct gctatttcta catcacgatt gattggagct
    13921 gggtgcatga ggattgctgt ttctttcaaa cgatcgtaac gttcttgagt caagccatgt
    13981 tgggcatggt agtcttcttt tgaaaataca gctccactat catggcgttc gtgttgcaca
    14041 cggagaaaca tcatgacatc aacctgatca atgatttcat caatggttac aaactgtcca
    14101 tagtctgcaa actcttgact tctccattcc tcaggtccag cgaaaaagag ttcagatccc
    14161 aagcgtttca aaatctgcat attggatttg gcaacgcgtg agtggtccaa gtcacctgca
    14221 atagcaactt taagaccctc aaagtggcca aattcctcat aaatggtcat caaatcaagc
    14281 aagctctggc tagggtgttg gcccgaacca tctccaccat tgatgatgga agtcgtaatc
    14341 gttggactag caatcaattc tctatagtag tcgacctctg gatggcgaat cacacagaca
    14401 tccactccta aagcagacag agtcaaaatg gtgtcataaa gtgtctcacc cttattaacc
    14461 gaactagtct tcacatcaaa gtcaagtcgt tccaatccaa gtttaatctc tgcgacttca
    14521 aaggacttat gtgtccgtgt agaatcctca aagaagagat tggaaacaat cggatggtct
    14581 tcatagggaa gctgggctcc atttttaaac tcaattcctc gcttgatcaa tttcattact
    14641 tgatcgacag tgaggtcttc catggacacc acatggttca atgcttgttg attttctgac
    14701 atggctactc ctttaacttt ctaagcttct tcagtaatca gaactctgtc ttggtcatca
    14761 agttctgtca tctctacgat gatttcttca gaacgactgg ttgggatatt ttttccaacg
    14821 taatctggac ggattggcaa ttctctatgt ccacgatcga ctagaactgc taaactcaca
    14881 cgcgcaggac gaccatgacc gacaatatta tcaatagcag cacggatggt acgacctgta
    14941 tagagcacat catccaccaa gataacttcg cggtctgtca catcgacaga aaccaaagaa
    15001 gtatcttctc cacttttaac atcatcacgg aaaggtttag tatccaattc cacaacagga
    15061 actgaaagat tttctaactg cttcaaacgt tcttggattc ggtgggcaat aaagacacca
    15121 cgagttttaa taccagccaa gacgatctta ttcaaatctt tgttgcgttc gataatctca
    15181 taagtaatac gcgtaatcgc tcgtttgacg gtcaattcgt ctacaacttc ttttgttttc
    15241 atgacaaacc tccaaaaaga aaagtctcct taaacaagga gacttgaaat ttatagccaa
    15301 gcgagcccta ctgcacacag tatagacttc acccttctac tttatcgcgc tccttgcctg
    15361 cctcacggga caggtttaaa ggaatattta gttatcattt actatagcac aaagcatgct
    15421 taaaatcaag caaaaagttt caatgtagca tcttacaaat tgctaaaatc atataattgt
    15481 gggtactggt cacactctgg attttttgga tggcaaatgg ctcttccaaa ataaatcatg
    15541 gcctgatggg cagctaacca ctgctcaggc ggcaagatat ccatgacccg cttttccacc
    15601 tcaagtggcg tcgctgattt tttgacaata tcgtggtgtt tgcaaatacg ctccacatga
    15661 gtatcaactg caaaggctgg aatcccaaat cctacactca tgacaacatt ggctgtcttg
    15721 cgaccaacac ctgccaaact ctccaattct tcacgtgtct gagggacttg accatcaaaa
    15781 tcgtctagta actgttgggc acatttttta aggaatttag ctttattccg atacaatccc
    15841 aagcgagaaa tatgtgaagc aatctcactc tctgtcgcta cagacatagc ttggggtgtt
    15901 ggaaaggcaa caaagagacc tggtgtggcc ttatttaccg ctgcatctgt cgtctgggct
    15961 gataacatga ccgcaaccag gagttcaaaa tgattggtaa aatcaagact aggcttggca
    16021 tctgggaaga gggcaatgat ttcttctagc acctttcgtg ctcgtttttt tgacaagacc
    16081 attattcatc tccgtcaaat agtccttgta agccagcaaa aggactgttt tcttctttct
    16141 ttactgcttg ttgagcttgg tattcttcct ctgtcatgat ttgccagtca tttcctgaga
    16201 caaatccttg accagcttct tcttcagccg tcaagacctt gataggaatg tttagcaaga
    16261 tattgtctga tacactctca gcaaggtcaa gcgcctcatt ttcgatgggc aagaccaagt
    16321 catcatctaa aatttcttga tttagatggt tagttgcgcc ttccatgaaa acttccgtga
    16381 ctggataaga ttcaactaac tcaactggct ccatactgcg actcgaagca agaacaatgg
    16441 tataagatag ttgataatct aagaaataca tacggtcttc atattgtact ttcccaactg
    16501 caaggatatc ttttacatct aaaatttctt gattacgtgc acgcaggtca tcaactaaat
    16561 ctaacgtttg ttcaaagttc aaaccttcag actgcttacg aatttcttga atatttaatt
    16621 tcatacttcc tccataaaga tttactctct tgattatacc atgaaaaggc tacaaatcag
    16681 cacaccaaac tttgtaatta aaattcagaa ttttaacata tttactatga cagttttgtt
    16741 ttttagtgct atactatagg gaaagagtac atcagatcaa ggaggatgct cacatggaag
    16801 acaagaaact cattcaactc ctatccaagt taaataaaag ctaccaaaac tgtaaacagg
    16861 gtacggcaga tgatattcga ctacaagagc tgctaaacac tactatgcaa gagctcaaaa
    16921 aaacggaaaa gttgaacaac agtatcttaa ttgatcttga gaaattttac caacccacca
    16981 gtcttctgat tggactgggt agcctaaaac taaacgatca agcacgcact gcttggcgaa
    17041 actatgataa attccattac gagcatgtca aacacgtact aagtctctat ggacctgttt
    17101 ttggatttta gagcatagaa tttccagttt tctgttgaca aaatttcctt aaaggtataa
    17161 tataaagata ctaatactcg gaggtaaggg agacatgaac aactaagtct atcaaataaa
    17221 gaacctttat ttagtagatc ttgtttttgt ctctttttgt gtgctctttt atgctctttt
    17281 tctggcatgt taatagagtt tttttgacat agactttggg ctctactagg taaagtagag
    17341 ctttttgtta tgcactatga acattctaga aagggaaatc atatgataaa aatcaatcat
    17401 ctaaccatca cacaaaacaa agatttacga gatcttgtat ctgacctaag catgaccatc
    17461 caagacgggg aaaaggttgc tattattggt gaagaaggaa atggcaaatc aaccttactt
    17521 aaaattttaa tgggggaagc tttgtctgat ttcactatca agggaaacat ccaatctgac
    17581 tatcagtcac tggcctacat tcctcaaaaa cttcccgagg agctgaaaaa gaaaacttta
    17641 cacgactact tctttttaga ttctattgat ttagactaca gtatcctcta tcgtttggcg
    17701 gaggaattgc attttgatag caatcgtttc gcaagtgacc aaaagattgg caatctatca
    17761 gggggagaag ctttgaaaat tcagcttatc catgagttag ccaaaccctt tgagattcta
    17821 tttttagatg aaccttcaaa tgacctagac cttgagacag ttgattggct aaaaggccag
    17881 attcaaaaga ccaggcaaac cgttattttc atttcccatg atgaagactt tctttctgaa
    17941 acagcagaca ctattgttca cttgcgactg gtcaaacacc gtaaagaagc ggaaacgcta
    18001 gtagagcatt tagactatga tagctatagt gagcagagaa aggctaattt tgccaaacaa
    18061 agtcagcaag ctgctaacaa ccaaagagcc tacgataaaa ccatggaaaa acatcggaga
    18121 gttaagcaaa atgtagaaac tgcgcttcga gctaccaaag atagtactgc cggtcgccta
    18181 ttggctaaaa agatgaaaac tgtcctctca caagaaaaac gctacgaaaa gacagctcag
    18241 tccatgactc aaaagccact tgaagaggaa caaatccaac ttttcttttc agacatccaa
    18301 ccattaccag cttctaaagt cttagtccaa ctggaaaaag aaaatttgtc cattgacgac
    18361 cgagttttgg ttcaaaaact acaactaact gtccgtgggc aagaaaaaat cggtattatc
    18421 gggccaaatg gtgttgggaa atcaactctg ttagccaaat taaagcaact tctgaatgat
    18481 aaaagagaga tttcccttgg ttttatgcca caagattacc acaaaaaact gcaattggat
    18541 ttatcaccaa tagcttatat cagcaaaact ggggaaaaag aggaacttca gaaaatccaa
    18601 tctcacctag ccagtctcaa tttcagttat ccagaaatgc agcatcaaat tcgctcctta
    18661 tctggcggac aacagggaaa actcctgctt ttggatttag tcctgcgcaa accaaacttt
    18721 ctcctgctgg atgaacccac acgaaacttt tctcccactt ctcaacccca aatcagaaaa
    18781 ctctttgcaa cctatccagg cggtctcatc actgtttcgc atgaccgtcg tttcttaaaa
    18841 gaaatctgct cgatcatcta tcgcatgaca gaacacggtt tgaagctagt taatttagaa
    18901 gatttataaa tttgcaacat agcagatagg tggggcaaaa acacaatttt aggagaaaaa
    18961 gaagtaaatc ttcccatagt aaaacgcata atatcaagtt ttcacacctg atattatgcg
    19021 tttttcagat tttaaagact tttttccagc cttcatttta catctgtttt aaacgttcaa
    19081 tccgttctga gataggtggg tgggtataaa agagtttttg gaacccccca cctttcttgg
    19141 gatcattgat ataaagagca ctgctagcat catcgacgtg gcgactcata ggtttgctat
    19201 tgtccaactt atctagggca ttaatcattc cctggggatt gcgagtcagc tcgacactag
    19261 atgcatctgc cagaaattcc ctctgacgag aaatagcgag ctgaaccaag gttgcagcga
    19321 gaggtgccag tacaatagct agtagggaaa ccactagcat aatgatttca agaccatttc
    19381 catctcggtc atcatcactt cgtctgcgac ctgctccacc ccaccacatc atacgacctg
    19441 ccataccaga aagcatggtg atagcactaa caagggcaac tgcaatagtc gaaatacgga
    19501 tatcataatt acgaatatga ctgacttcat gtcccataac agcttctagt tcttcacgat
    19561 tcatgatagc tagtagacct gaagtcgcag caacagccgc attttgagga ttagaacctg
    19621 tcgcaaaggc atttaaggct ggatcatcaa tgatgaaaac acggggcata ggaatctgag
    19681 cgaccagagc catatcttcc actacatggt agaggtctgg tgccgtttgc tcatccacct
    19741 cacgcgctcc attcatggac atgacaatct ctgtcgattg aaaaatcata gacaaagcgt
    19801 agataaagcc gataatcagt gcgataacca aaccaccaag tccagatctt ataaagagat
    19861 aaccaaccgc ataaccaaca agagctaaga gtaggaaaaa taccagcaac aaaatccagg
    19921 tttttcgttt attgcttgca atttgatcaa acaacatctt agtcacctaa accgctaaaa
    19981 tcaactttag gaaccgactt ttcctcttca ggtgtttgaa ggaaatctgc cgctttaaat
    20041 ccaaacattc cagcgataat attgctcggg aaagtttcta attttacatt gtagttgctg
    20101 acaacactgt tatagagttg acgagagtaa gaaattttat tttctgtgtt tgtcaactcc
    20161 tcttgcaatt taacaaagtt agcactagct ttcaaatctg gatagctttc tgcaactgca
    20221 aaaatacctg aaacctgacg agtgagggca tcactggctt tcatagcttc tgctggtgaa
    20281 gtcgctgccg ccacttggtt acgtagttct gccacctttt caagggtaga accttcatat
    20341 ttggcataac cttttacagt ctcaatcaag tttggcaaga gatcattgcg acgtttcaac
    20401 tgaacatcaa tctgactcca agcctccttg gtttgcatac gatttttaac caaaccgtta
    20461 tagctaacaa tcacaaaaat aacaataaga gcgataactc caagaataat ccaagtcatg
    20521 atataagtcc tttctacttt tagattagta ccagtatatc aaatttttaa tgattgtggt
    20581 aaaataagat gatactaaag aaggaaataa ctatgaaacc agaaacattt tacaacttgc
    20641 ttgccgagca gaatcttcca ctttcgaacc agcaaaaaga acaatttgaa cgttattttg
    20701 agctcttggt cgagtggaat gagaagatta atttgacggc gattacggac aaggaagaag
    20761 tttatctcaa acatttttac gattcgattg cacccattct tcaaggtttg attcccaatg
    20821 aaactatcaa acttcttgat atcggggctg gggcaggatt tcctagtcta ccaatgaaaa
    20881 ttctctatcc ggagttagat gtgaccatta ttgattcact caataagcgc atcaacttcc
    20941 tacaactctt ggctcaagaa ctggatttga acggagttca tttctaccac ggacgtgccg
    21001 aagattttgc ccaagacaag aacttccgtg ctcaatatga ttttgtaaca gctcgtgcgg
    21061 ttgcccgtat gcaggtccta tctgaattga ctattcccta ccttaaggtt ggtggaaaac
    21121 tattggcact caaggccagc aatgcgcctg aggagttgtt agaagctaag aatgccctca
    21181 atctcctttt tagtaaagtc gaagacaatc tcagctacgc cctaccaaat agagatccgc
    21241 gttacatcac agtggtagaa aagaaaaaag aaacaccaaa taaatatcca cgtaaggctg
    21301 gtatgccaaa taaacgcccg ctttaaattt ttaagtaaaa aaatatttac aaaatcaacc
    21361 tcgctctctt atttttaggc tcgggaaaaa atgatttaca aaatcagcct cgctctttta
    21421 tttctaggct cgggaaaaaa tgatttacaa aatcagcctc gctcttttat ttctaggctc
    21481 gggaaaaaat gatttacaaa atcatttttt tctgctatac tatcctaagc aaaggttttt
    21541 aatgtcatcc cgtgaggtga cgaagacgca aaaatatttg aaactcttta aagtctagat
    21601 tttagagaag tcttactctg agggcctatt gctgtaaaat aatgggctct tttctgatgc
    21661 ccaaaagtga ggtttatatg aaacaagaat caactgttga tttgttacta gacgttgacc
    21721 aacgtccttc ggatggaaaa ggaattctcc ttagcttcca acacgttttc gccatgtttg
    21781 gtgcgaccat cttggtacca ttgattttgg gaatgcctgt atctgttgcc ctttttgctt
    21841 caggtgttgg aacactcatc tacatgattg ctactggttt taaagttcca gtttatctag
    21901 gttcttcatt tgcctttatc acagctatgt cactggctat gaaagaaatg gggggtgatg
    21961 tatctgctgc ccaaacaggg gttatcttga ctggtttggt ctatgtcctt gttgctacca
    22021 gcatccgatt tgtaggaaca aaatggattg ataaactctt gccaccaatc attatcggtc
    22081 ctatgatcat cgttatcggt cttggacttg caggttcagc tgttaccaat gcaggtcttg
    22141 tagcagacgg aaattggaaa aatgctctgg tagccgttgt tactttccta attgctgcct
    22201 ttatcaatac aaaaggaaaa ggcttcctac gaatcattcc attcctcttt gccattatcg
    22261 gtggttacct tttcgcacta actcttggct tggttgactt tacaccagtt cttaaagcca
    22321 actggttcga aattcctggt ttctacttgc catttagcac aggtggtgcc tttaaagagt
    22381 acaatcttta ctttggtcca gaagccatcg ctatcttgcc aatcgctatc gtaacaattt
    22441 ctgaacatat cggagaccat actgttttgg gtcaaatctg tggtcgtcaa ttcttaaaag
    22501 aaccaggtct tcaccgtact cttcttggtg acggtatcgc aacttctgtt tctgccttcc
    22561 ttggtggacc agccaataca acttacggag aaaatacagg ggttatcggt atgactcgta
    22621 tcgcttctgt ctcagttatc cgtaacgctg ccttcatcgc gattgccctc agcttccttg
    22681 gtaaattcac tgccttgatt tcaactattc caaacgctgt acttggtggt atgtcaatcc
    22741 ttctctatgg ggttatcgcc agcaatggtt tgaaagtctt gattaaagaa cgtgttgatt
    22801 tcgctcaaat gcgaaacctc atcatcgcaa gtgctatgtt ggttcttgga cttggaggag
    22861 ctatccttaa acttggtcca gttacacttt caggtactgc cctttcagcc atgacaggaa
    22921 tcatcttgaa cttgatcttg ccatacgaaa ataaagacta agagtctaaa tacacctaat
    22981 ccactcagac agctgagtgg atttttcgta tattataata aaagtgtctt aacaaaatta
    23041 ttaaaatcaa aaaacgtata atatcagata ttctaaaacc ttgatactgt acgttttatc
    23101 atagaaattt ttactttatt ttctcatcaa atgagatttg catcaatctc ttgtcttact
    23161 tgcgtttctt cttcgctttc ttcattttgt tagccatacg tttcatggac tgtttcatgg
    23221 caaattcacc aattttacct ttcaaaccgc caccaaacat ctggctcata tctggcattc
    23281 ctgctcctcc gagagctgat aagtcaggca taccgccttg tcccatcatt ccttcaaggg
    23341 cagacatatc cattcctccc atatttggca tatttttagg aaggttattt ggattaatcc
    23401 ccatttgctt catcatttta ttcatatccc cagacataac accctgcatg agctgtttag
    23461 cctggttaaa gtccttgatg aatttattga cttcgacgaa tgtatttcca gaaccagcag
    23521 caatacgacg gcgacggctt ggatttaaca aatctgggtt ttcacgttct tcaggtgtca
    23581 tcgaagacac aatggcacgt ttacgagcaa tctggcgttc atccaccttc atgttttgaa
    23641 gtgctggatt gttggccata cctggaatca tcttgagcaa gtcttccatc ggccccatat
    23701 tttgcacctg atctaattga tcgatgaaat cattaaaatc aaaggtgttt tcgcgcatct
    23761 tctcagccat ttcaagggct ttttgttcat cgtattcctg agaagctttc tcaatcaaag
    23821 tgagcatatc ccccatgcca aggatacggc tagacatgcg gtctgggtgg aaggtttcaa
    23881 tgtccgtaat cttttcacct gtaccagtga acttgattgg ttttccagta atgtgacgaa
    23941 cagacagagc agcaccacca cgagtatcgc catcaatctt ggtaaggatg accccagtca
    24001 cttccaactg agcattaaac tcacgcgcaa cattggctgc ttcctgacca atcatagcat
    24061 caacgacaag caagatttca tttggttgag ccaatgcttt cacatcacga agctcattca
    24121 tgaggagctc atcaatctgc aaacgacccg cagtatcaat caagacatag tcgttatgat
    24181 tagtttgggc ttgctccaaa ccttgacgta caatctcaac agctggtact tctgttccaa
    24241 gtgcaaagac aggcacatca atctgttgtc ccaaggtctt aagctggtca atggcagctg
    24301 gacgataaat atccgccgca atcatcaaag gacgagcatt ttcttctttc ttgagtttgt
    24361 tggccaattt accagcaaag gttgttttac cagccccttg taaaccaacc atcatgatga
    24421 tggttggaat cttaggtgac ttgataattt ctgccgtatc agaacctaaa acggctgtca
    24481 gttcctcatc aacgatttta ataatctgtt gcgcaggatt aagtgtatca atgacctcat
    24541 gcccgactgc acgctcacga actttcttga taaagtcctt tacaacaggc aaggcaacgt
    24601 cggcctcgag caaggccaag cgaatttctt tggttgcctc ttggacatca gattcagaga
    24661 tttttccttt tttacgtaga tttttaaaga cgttctgcaa acgttctgtt aaactttcaa
    24721 atgccatttt tcttcctctt attctctatt atcaatgctt gttaaaattt ctatctgctc
    24781 ctgcagaaag ttatccttgg gatagcgctc caaaatctga tcaaaaatct gactgcggac
    24841 aatatagtcc gagtacatgt gcaatttcat ctcataatct tccagaatct tttctgttcg
    24901 cttgatattg tcatagacag cctgacgact gacaccgaac tcctcggcaa tttcagcaag
    24961 gctgtaatca tcagcgtagt agagctcgat ataattcatt tgcttatctg tcaaaagcgc
    25021 cgcataaaat tcaaagagcg cattcatacg attggttttt tcgatttcca taacttttat
    25081 tataccaaaa attagcctaa tctaccacac taggaagccg atccaagaag atagatagct
    25141 aaatttgaaa aagacatgag cctagcccca agtaatttcc aattgatagc tggcaaaggg
    25201 atgtccctct tgattttgta gttgataatc tagttcaatc ttttgcctat caacttgata
    25261 atggctcgtt tggatggtaa actcctgcat acccataggt gtgggaatat aggctaaact
    25321 atcactatcc tttagaaagc gcataatggt cttgggattg gaaaatcgac tcatcacaag
    25381 ttcttgacca tgaaatttaa tcactacttt ttccttttcc tcattataga aaagcaggta
    25441 gctataatct cctttttcat gcacttccac atcataaagc tggtcaatca cttccaactg
    25501 ctcatcaaac tgaattgtat ttcgcatccg aatcttcaca tcaggccctc tttcttgtct
    25561 cttgtcctac tattttacca aaaagagcag gattttgcta taatggtcat atgaacgaaa
    25621 aagtattccg tgaccctgtt cacaactaca tccatgtcaa taatcaaatc atctatgact
    25681 tgattaatac aaaagaattt cagcgtttgc gccggatcaa acaactggga acttccagtt
    25741 ataccttcca cggtggagaa cacagtcgct tctctcactg tctaggagtc tatgaaattg
    25801 cacgacgcat cacagagatt ttcgaagaaa aatatcctga ggaatggaat cctgccgagt
    25861 ctctcttgac catgaccgct gctctcctac acgaccttgg gcatggtgcc tactcccata
    25921 cttttgaaaa tctctttgat acagaccatg aagccattac tcaggagatt attcaaaatc
    25981 ctgagacaga gattcaccaa gtcctgctac aagtggcacc tgatttccca gaaaaggtgg
    26041 ccagtgtcat tgaccatacc tatcctaata agcaggtcgt gcagctcatt tctagtcaga
    26101 ttgacgcaga tcgcatggac tatctcttgc gcgactccta ttttacagga gcatcctatg
    26161 gggaatttga cctgactcga atcctccgag tcattcgtcc tatcgaaaat ggtatcgcct
    26221 ttcagcgcaa tggcatgcac gccatcgaag actacgtcct cagtcgctac cagatgtaca
    26281 tgcaggttta tttccacccc gcaacacgcg ccatggaagt tctcctacag aatcttctca
    26341 aacgcgccaa ggaactctat cctgaggaca aggatttctt tgcccgaact tctccacacc
    26401 tcctgccttt cttcgaaaaa aatgtgacct tgactgacta tctggctctg gatgatggcg
    26461 tgatgaatac ctacttccag ctttggatga ccagtcctga caagattctt gcagatttat
    26521 cgcaacgctt tgtcaaccgc aaggtcttta aatccattag cttttcgcaa gaggatcaag
    26581 accaactcgc cagcatgaga aaattagctg aggatatcgg ctttgatccc gactactaca
    26641 ctgccattca taagaacttt gacctccctt atgatatcta tcgtcccgaa tctgaaaacc
    26701 cacggacaca gattgagatt ttacaaaaaa atggagaact ggcagaactc tctagcctgt
    26761 cccctatcgt ccaatccctt gctggaagtc gccacggaga taatcgcttt tatttcccga
    26821 aagaaatgtt agaccaaaac agcatcttcg caagcatcac ccagcaattt ttacacttga
    26881 ttgagaacga tcattttacc ccaaataaaa actaaaagag gaaatttatg agtattaaac
    26941 taatcgccgt cgatattgac ggaaccctag tcaacagcca aaaggaaatc actcctgaag
    27001 tcttttctgc catccaagat gccaaagaag ctggtgtcaa agtcgtgatt gcaactggcc
    27061 gccccatcgc aggtgttgcc aaacttctgg acgacttgca gttgagagac caaggtgact
    27121 atgtggtgac cttcaatggt gcccttgtcc aagaaactgc tactggccat gagattatca
    27181 gcgaatcctt gacctatgag gattatctgg atatggaatt cctcagtcgc aagctcggtg
    27241 tccacatgca tgccattacc aaggacggta tctatactgc aaatcgcaat atcggaaaat
    27301 acactgtaca cgaatcaacc ctcgtcagca tgcctatctt ctaccgtacc cctgaagaaa
    27361 tggctggcaa ggaaattgtc aagtgtatgt tcatcgatga accagaaatc ctcgatgctg
    27421 cgattgaaaa aataccagcc gaattttacg agcactactc tatcaacaaa tctgctcctt
    27481 tctacctcga actccttaaa aagaatgtag acaagggttc agctattact cacttagctg
    27541 aaaaactagg attgaccaaa gatgaaacca tggcaatcgg tgacgaagaa aatgaccgtg
    27601 ccatgctgga agtcgttgga aaccccgttg tcatggaaaa tggaaatcca gaaatcaaaa
    27661 aaatcgccaa atacatcact aaaacaaatg acgaatccgg cgttgcccac gccatccgaa
    27721 catgggtact gtaaaagtat catttttcaa taagaattga ttagcaataa aatccaatga
    27781 atttttttag caaactattt aatttaaaac aaaataatca taatagagac acaaattctg
    27841 attgtaacaa tttttaccta aacgaattag aatgtggcct tactcctggg caactcatac
    27901 tcatagattg gactcaaaaa acagggagaa attataattt cccaagatat tttaaatact
    27961 ctcttcaaat tgaccctgaa tctacacaca atcaattata caaattagga tacttcacta
    28021 aaaataagac tttatcatat cttacagtag tagaattaaa aactatatta tctaaacata
    28081 atttagctac ttctggaaaa aaagcagaat taattacaag aataattaat aatgttaaca
    28141 ttgacaattt agatattccg ttcgaattta aactaacaaa agaagcacaa aatcttatta
    28201 tcgaacatag tgactatatc aaagcatact atgataaaga cataactatg gaagattatt
    28261 gtaaagaaaa aaacaatatc tcttttaaag caacttttgg tgatataaaa tggagtctct
    28321 taaataaaca agctcatagg aatactgtat caggagattt tggatgctta tctaacacac
    28381 gaaaggctca gggaagacat ttggaacaag aaggtaatat taaacatgct ttaatatatt
    28441 acatagaatc tttgataatt actatttcag gattagaaaa caatttttca gccactgatt
    28501 atccagtata ttatcccgat tcgatacctg actactcact aaaacatatt caaacattaa
    28561 tggaatcatt atctgatgac gattatgatt ttgcttttga tgaagcatta tttcgcttct
    28621 caattttgaa tgcaaatcat tttttatcta aggaagatat tgactattta agagttaatt
    28681 tacctcgttc cactgctgaa gaaataaaca attacttaaa gaaatatgaa tgttatagtc
    28741 ctttaaataa tttagaactt gacgattttg aataaattga ctatacaaac atttatatac
    28801 tcgatatagt ctcaatttta tctgatgatt gcccaaattt ttcaataata aaacgcataa
    28861 tattatggag acaatcccct atattatgcg ttcttttaat atcaaagact ttttgacaaa
    28921 cttctttgat atctaattac atgccccctg caggaatcga acctgcaact actccttagg
    28981 agggagttgt tatatccatt gaactaaggg agctagataa aaactctgct gaaaagcaga
    29041 gttttttagt cgaattaacg acggatttct ttgatacgag ctgccttacc ttgaagagca
    29101 cgcaagtagt acaatttcgc acgacgtact ttaccgtaac gtacaacttc gattttttca
    29161 acacgtggag tgtggattgg gaagatacgc tcaacaccta caccgttaga gattttacga
    29221 actgtatagt tttcagagat gccagcacct ttacgtgcaa taacaacacc ttcaaaaatc
    29281 tggatacgtt cacggttacc ttcgacaact ttcgcatgta cacgaacagt gtcaccagga
    29341 cggaatgatg ggatatctgt acgaagttga ccttcagtca agctttggat taatggattc
    29401 attttattct cctatctttg tcaatcttga ggaatcttcc tcagcggata aactgtattt
    29461 ttgtgcgtcc attacacaca agatatagtt taccaaattt ctaaaaaaaa gtaaagaaat
    29521 ttatagcaaa attcctaaaa aaatcgcaac caaaccacct atgtaagtca aagtcaggta
    29581 agaataaaag accttcttat cacttagcag tctttgaagt tcgtcattca aggtcgaaaa
    29641 agttgttaaa ccgccacaaa atcctgttgc tagaatagca tatacttcct tagactctac
    29701 atgattgtag aatactccaa ttaaaaaaca acctaaaaga ttagctatga gcgttccgag
    29761 tggcaattta gaagcttgat tatagcgaga aaagaaatac cgtacgagtg ctcccaagcc
    29821 acaggcgatt gcaagataga cgattaccat ttcttcctcc ccaaatagta agctaaaagc
    29881 aggcctccac cgatactcaa aagcaaatac agtatcaaac taagataacg ccctgtatca
    29941 agcagcttca cagtatcaag cattagactg gaaaaagttg ttaaacctcc gcaaaaaccc
    30001 gtccccagtg ctaaaatcaa gcccttacta gtccccttat agaccagata gcccttgaca
    30061 agataaatca agcagaaaat tcccagatag ttgacaaaga gagtgcccca agggaaatct
    30121 ggactggctg gtaaccaagt ggaaactagg tagcggacaa gtccgcccaa catagcagct
    30181 agaaaaatcc ctagcggata aaattgttct tttttcattt gatattttga tcctgataat
    30241 cacgcgaacg tttgagtatg tccgaaaaag tcgcgacaat agtctcctga tagcgcttgt
    30301 cctctacacg acttctaacc ttttcaaaaa taactgcttc tctcttagta tctaaaatcg
    30361 gtttccctga agccttctta taagcgacaa ctccttcaac taagtgcatt cgttcttcta
    30421 acagtttgac aatttggtcg tcgatttgat cgatttcttg acgaataata tctaaatcca
    30481 tacagtctcc tcctttattt gaattattgt atcaaaaagc catcaattag gctagtaaaa
    30541 tcccaactct cgataagaaa aatgcactga ttgattacat cagcgcactt ttatgcttat
    30601 cctactttag caaccaattc ttctgcgaat tgttccaagc gttcaatatc ttcttcctcg
    30661 gcagaaagat caactttaac acactctgaa cctttttctg ctcctgttga cacaaagaca
    30721 cggtcaaagt catcaacagc cttacagaat tcatcgtaga aggtatctcc tgagccgacc
    30781 actccgtaga ttttgccatt caagttgaga tctgctaggt cttcgtagaa gtccatcatc
    30841 tcatctggca attcaccatc accataagta taggtcgcaa cgatagcgat gtctgcttcc
    30901 aagaagtctg aagcgtcaac agttgtacat tcatcaacat caacatccaa gcccaagtca
    30961 cgtaatttgt ctgctacaat atctgcaatt tcttcggtat taccggtcat actggcaaat
    31021 acaatttttg ctaatgccat atcgtcctcc tcaatttatc tttctccatt atatcacatc
    31081 tttttcattt taaaaataaa aattcttgtg ctacaatgaa atgagaaaga attgaggtta
    31141 tttatggaga tttgccaaca aattttagaa aaaattaaag aatacgacac cattatcatt
    31201 catcgtcata tgaaaccaga ccctgatgcc ttgggaagtc aggtgggatt gaaagccttg
    31261 ctggaacatc atttcccaga aaaaaccatc aaagccgtcg gttttgatga accaactctt
    31321 acttggatgg ctgagatgga tcttgttgaa gatagagcct accaaggcgc acttgtcatc
    31381 gtctgtgata cagctaatac tgctcgtatc gatgataagc gctatagtca aggtgatttt
    31441 ctcattaaga ttgaccacca tccaaatgat gatgtatacg gtgacctgtc ttgggtcgat
    31501 actagttcaa gtagcgctag cgagatgatt accctatttg cccaaacaac ccaactagcc
    31561 ttggcagatc gcgatgctga gttgctcttt gcaggaattg tcggtgatac aggtcgcttc
    31621 ctctaccctt ctaccactgc acggactctt cgtctggctg cttatttgag agaacataac
    31681 tttgactttg cggctctcac tcgcaaaatg gacactatga gctacaaaat tgctaaactg
    31741 caaggctaca tctacgacca tctggaagtg gatgaaaatg gtgctgctcg cgttatcctg
    31801 agtcaagaag tcttgaaaca atacaatgta accgatgctg aaactgcagc cattgtcggt
    31861 gcacctggac gcattgacag agtgagtctc tggggaattt ttgtcgaaca ggctgatggc
    31921 cactaccgag ttcgcttacg cagtaaagtc catcctatca atgaaattgc caaggagcat
    31981 gatggtggag gccaccctct agcaagtggt gctaattcct atagcctaga agaaaacgaa
    32041 atcatctacc aaaagttaaa aaacttgctt aaaaactgat aaaatacttg ccaaactttt
    32101 cagaatctga tagactagta tggtaacaat ctatggctcg caaagagacc atggcagaaa
    32161 ggaaatattg caaaatgaaa aaagatatcc atccagaata tcgcccagtt gtcttcatgg
    32221 acacaactac tggttaccaa ttccttagcg gttcaacaaa acgctctaac gaaacagttg
    32281 agttcgaagg cgaaacttac ccattgatcc gtgtggaaat ttcatcagac tcacacccat
    32341 tctacactgg acgtcaaaag ttcactcaag cagatggacg cgtggatcgt ttcaacaaaa
    32401 aatacggtct caaataatga taagagaaca gtttcggctg ttcttttttg tttcttgaaa
    32461 tcaactgctg ttttcatgtt ccagactcat ctgtaggttc ggtttccatg ctactaggca
    32521 ggaaggaaat agctgtttca acacgtccat aatgagctgt actattgtca cgaaccacac
    32581 tttcattgat ggtccaagtg gaattcattt tcttaaaagc ttctcggact ttttccaaat
    32641 ctttggaggc aatggcctgc tctaaggttt caaaacgagg acttagacgg tttaccaatt
    32701 tttccttttc cgcatctagg tcaacaggat tttgttcttt ttcaaaagct aatagagctg
    32761 aggaaatttc ggtgagtttg gcttcagtaa tatctccaga tagagctaac ttttccttaa
    32821 caatcttacc aacctcagaa tccttatttt ctactctttc gaagtctgat gccatcttcg
    32881 taacgagttt ctggacctca gcctgatcac catttttaac cgctttggat gcatctgtga
    32941 tttttacgaa ataagaactc aagctttctt gggcacctgc tggggaaaga attaagaatt
    33001 aagaattaag aattaagaat taagaattaa aaatgacaaa gctaaaacaa gcaaccagct
    33061 tttagccttc caataatttc tgaccaatgt agcctccttt ctccacacca ccaaagcaag
    33121 taaaaagtcc actacctatg tgagtgatgt attcattcat cttatcagta gcacctaggt
    33181 tagtttgaac cttaacaaag ttatcaggat ccttctggaa agaaatgaag agcaaacccg
    33241 tatcaaactg accagtcttt tcatcaatgc catctgagta agaataagaa cgacgtaaaa
    33301 gtggcttatc cacttctttg gccaaacaaa catgcgaatc atcaggtaag agactcaaat
    33361 ccacttcatc aaactcattt ttcttaccaa agggggcacc gcatttctcc ccttacggat
    33421 gagattgcga atagcgtgaa aggcaatttg ctcatcatct gcacaagcat gaatcacaat
    33481 atctccacca gtatattttt cacgtaattg ctccttagga aatagaggta aatccctgaa
    33541 cagtcgaggg cgcttgtttt ccaagttcat ccttttcaag aaacttgcag atacaccaaa
    33601 agtcagcgtc aaacgatgag gattgagccc aactgtcatc cgtccaatcc ttgaatagct
    33661 ggataatttt atctctatcc gtcgtatgca ggtccaagac aacaaaatag atattctttt
    33721 gcatgggcgt actatttggt acatcaagcg aaccttatga aaaggtctac tgattttaaa
    33781 gcgctttctt gtcttcttga attgagattt tatttttaga cgcgacaatg gtttgagcgt
    33841 ctgctttctt aggatgttct ggacgtggca taatatttcg ccaaccatgg cgcttcaaca
    33901 gttgatagaa ggcgtcacgt gtgtaggaac gacctaactc ctttttataa gcctgaaata
    33961 aggcatcaat tgtaacaaat tctcctgact ctgcagcctt caaatgacgg gcaagaaagg
    34021 ctttctcttc ctcaactgtc atatatgcat ggttacgacc actacgtgtt tcttgaagga
    34081 gagagtcgag ttcgaactcc tcatattttt ttacatttcg ctaaatcgtt gtttgattac
    34141 agtctaaaag ttctataatc tctttataag atttgcccat cagacgaaat ataataaatt
    34201 gaaactagaa tagtacacct ctacttctaa aatattatta gaaatcgatt tg
//
LOCUS       DAVAGB010000018        34222 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVAGB010000018 DAVAGB010000000
VERSION     DAVAGB010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34222
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.018"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(<1..953)
                     /locus_tag="VQO19_001001"
     CDS             complement(<1..953)
                     /locus_tag="VQO19_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET1349285.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDITHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYD
                     LAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQFERKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRMHLTNKEILDKILSYSEDLKHHYQIYQL"
     gene            1220..1585
                     /locus_tag="VQO19_001002"
     CDS             1220..1585
                     /locus_tag="VQO19_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HET1349286.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            1661..2602
                     /locus_tag="VQO19_001003"
     CDS             1661..2602
                     /locus_tag="VQO19_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HET1349287.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHGLSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            2550..3566
                     /locus_tag="VQO19_001004"
     CDS             2550..3566
                     /locus_tag="VQO19_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HET1349288.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVIQMRAGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            3568..3894
                     /gene="comGC"
                     /locus_tag="VQO19_001005"
     CDS             3568..3894
                     /gene="comGC"
                     /locus_tag="VQO19_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HET1349289.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKDDGRITEEQAKAYKEYHDKNGEA
                     NRKVND"
     gene            3887..4291
                     /locus_tag="VQO19_001006"
     CDS             3887..4291
                     /locus_tag="VQO19_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HET1349290.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            4296..4556
                     /locus_tag="VQO19_001007"
     CDS             4296..4556
                     /locus_tag="VQO19_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349291.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            4519..4980
                     /locus_tag="VQO19_001008"
     CDS             4519..4980
                     /locus_tag="VQO19_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET1349292.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS"
     gene            4958..5371
                     /locus_tag="VQO19_001009"
     CDS             4958..5371
                     /locus_tag="VQO19_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET1349293.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEIATDSSEKVEKKKSEEKPEKKENS"
     gene            5508..6102
                     /locus_tag="VQO19_001010"
                     /pseudo
     CDS             5508..6102
                     /locus_tag="VQO19_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            6163..7116
                     /locus_tag="VQO19_001011"
     CDS             6163..7116
                     /locus_tag="VQO19_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET1349294.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            7167..8357
                     /locus_tag="VQO19_001012"
     CDS             7167..8357
                     /locus_tag="VQO19_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HET1349295.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGCSEQQILDIENHAQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKYIGQYLAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            8506..8877
                     /gene="rnpA"
                     /locus_tag="VQO19_001013"
     CDS             8506..8877
                     /gene="rnpA"
                     /locus_tag="VQO19_001013"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HET1349296.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYQEGNGSEKETKVD"
     gene            8852..9676
                     /locus_tag="VQO19_001014"
     CDS             8852..9676
                     /locus_tag="VQO19_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET1349297.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTILIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            9695..10681
                     /locus_tag="VQO19_001015"
     CDS             9695..10681
                     /locus_tag="VQO19_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HET1349298.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIETISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QAESQELEDLGLKVETNFDIEQVATEVMAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            10732..11355
                     /locus_tag="VQO19_001016"
     CDS             10732..11355
                     /locus_tag="VQO19_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HET1349299.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLEKQAKILDIPTVKGIYYLAYSDGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            11486..12943
                     /locus_tag="VQO19_001017"
     CDS             11486..12943
                     /locus_tag="VQO19_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET1349300.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            12966..13247
                     /locus_tag="VQO19_001018"
     CDS             12966..13247
                     /locus_tag="VQO19_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET1349301.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            13324..13809
                     /locus_tag="VQO19_001019"
     CDS             13324..13809
                     /locus_tag="VQO19_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET1349302.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            13826..14491
                     /locus_tag="VQO19_001020"
     CDS             13826..14491
                     /locus_tag="VQO19_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HET1349303.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAVDPAGAARAFKDEIKR
                     IWG"
     gene            14495..15358
                     /locus_tag="VQO19_001021"
     CDS             14495..15358
                     /locus_tag="VQO19_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HET1349304.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            15360..16064
                     /locus_tag="VQO19_001022"
     CDS             15360..16064
                     /locus_tag="VQO19_001022"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HET1349305.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVEPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            16241..17914
                     /locus_tag="VQO19_001023"
     CDS             16241..17914
                     /locus_tag="VQO19_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET1349306.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVTLQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINKEIVVQAFLEDI"
     gene            18026..19117
                     /gene="ulaG"
                     /locus_tag="VQO19_001024"
     CDS             18026..19117
                     /gene="ulaG"
                     /locus_tag="VQO19_001024"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HET1349307.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            19231..21207
                     /gene="tkt"
                     /locus_tag="VQO19_001025"
     CDS             19231..21207
                     /gene="tkt"
                     /locus_tag="VQO19_001025"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET1349308.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            21324..21623
                     /gene="yajC"
                     /locus_tag="VQO19_001026"
     CDS             21324..21623
                     /gene="yajC"
                     /locus_tag="VQO19_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET1349309.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            21670..22098
                     /locus_tag="VQO19_001027"
     CDS             21670..22098
                     /locus_tag="VQO19_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HET1349310.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQQYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            22100..22510
                     /locus_tag="VQO19_001028"
     CDS             22100..22510
                     /locus_tag="VQO19_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349311.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            22811..25462
                     /gene="adhE"
                     /locus_tag="VQO19_001029"
                     /gene_synonym="adhC"
     CDS             22811..25462
                     /gene="adhE"
                     /locus_tag="VQO19_001029"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HET1349312.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(26448..26756)
                     /locus_tag="VQO19_001030"
     CDS             complement(26448..26756)
                     /locus_tag="VQO19_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET1349313.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(26753..27061)
                     /locus_tag="VQO19_001031"
     CDS             complement(26753..27061)
                     /locus_tag="VQO19_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET1349314.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(27066..28361)
                     /locus_tag="VQO19_001032"
     CDS             complement(27066..28361)
                     /locus_tag="VQO19_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET1349315.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(28379..29788)
                     /locus_tag="VQO19_001033"
     CDS             complement(28379..29788)
                     /locus_tag="VQO19_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET1349316.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQIIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIGENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            29946..30674
                     /locus_tag="VQO19_001034"
     CDS             29946..30674
                     /locus_tag="VQO19_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET1349317.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            31133..31327
                     /locus_tag="VQO19_001035"
     CDS             31133..31327
                     /locus_tag="VQO19_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET1349318.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(31693..33003)
                     /locus_tag="VQO19_001036"
     CDS             complement(31693..33003)
                     /locus_tag="VQO19_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HET1349319.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            33240..34112
                     /locus_tag="VQO19_001037"
     CDS             33240..34112
                     /locus_tag="VQO19_001037"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HET1349320.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT        10693 a         6087 c         7249 g        10193 t
ORIGIN      
        1 agttgataga tctgatagtg gtgtttcaag tcttctgaat agcttaaaat cttgtcaaga
       61 atttctttat ttgttaagtg catgcgaaaa gtagggcgat aaaaacgttt atcgctcaat
      121 ttacgactat cctgttggat gagtttccag taacgcttga tagccttgta ttcatgagat
      181 tttcgttcaa actgattcat aatttgaaca cgaaaacgac tcatggcacg gctgagatgt
      241 tggataatat ggaaacgatc tagaacgatt ttagcacacg gaaaaagctg tttagccaag
      301 tcatagtaag gactaaacat atccatcgta atgattttca cttgacaacg aacggctcta
      361 tcgtagcgaa gaaagtgatt tcggatgaca gcttgtgttc tgccttcaag aacagtgata
      421 atattaagat tatcaaaatc ttgcgcaatg aaactcatct ttcccttagt gaaggcatac
      481 tcatcccaag acataatctt tggaagccga gaaaaatcat gctcaaagtg aaagtcattg
      541 agcttgcgaa taacagttga agttgaaatg gccagctgat gggtaatatc agtcatagaa
      601 attttttcaa ttaacttttg agcaattttt tggttgatga tacgagggat ttggtgattt
      661 ttctttacca ggggagtctc agcaaccatc atttttgaac agtgatagca cttgaaacgg
      721 cgttttctaa ggagaattct agtaggcata ccagttgttt cgaggtaagg gattttagaa
      781 ggtttttgaa agtcatattt cttcatttga cttccgcact cagggcaaga tggggcgtcg
      841 tagtccagtt tggcgatgat ttccttgtgt gtatccttat tgatgatgtc taaaatctgg
      901 atatttgggt ctttaatatc gagcagtttt gtgataaaat gtaattgttc catatgaatc
      961 tttctaatga tggttttgtc gcttttcatt ataggtcata tgggactttt tttctacaac
     1021 aaaataggct ccataatatc tataagggat ttacccacta caaatattat agagccaaat
     1081 atttttgtac ataagtaaat agaaattcag tcatccatca gatggctgga ttttttatca
     1141 aaaaattaag aaatgagcat atttctttcc ttgtctggcg gaattggtta taatatacgg
     1201 tacaaaggaa tgaatgaata tgtatcgtgt tatagaaatg tacggagatt ttgaaccgtg
     1261 gtggttctta gaaggttggg aagaagatat tgtagcaagt agaaaatttg accagtatta
     1321 tgatgctctc aaatactaca aaacttgctg gtttagattg gaacaagaat cccctcttta
     1381 taaaagtaga agcgacttga tgaccatttt ttgggacccg gaagaccaac gctggtgtga
     1441 tgaatgtgat gagtatttac aacaatacca ttctttggct cttttgcagg atgagcaggt
     1501 tatcccagac gaaaaactac gctcaggcta tgaaaaacaa accagtcagg aaaggaatcg
     1561 ttcttgccgt atgaaattaa aatagagaaa agtaactttt ttggagttgc tttttttatt
     1621 tttctaacgc tttgcgaata gtataggtga ggaggtaagt atggttcaag aaattgcaca
     1681 agaaatcatt cgctcggctc ggaaaaaagg ggcgcaagac atttattttg tccccaagtt
     1741 agacgcctat gagcttcata tgagggtagg agacgagcgc tgtaaaattg gtagctatga
     1801 ttttgaaaag tttgcagccg ttatcagtca ctttaagttt gtggcgggta tgaatgtggg
     1861 agaaaaaaga cgtagtcaac tgggttcctg tgattatgcc tatgaccaga agatggcgtc
     1921 tctacgttta tctactgtag gcgattatcg ggggcatgag agtttggtta tccgtttgtt
     1981 gcacgatgag gagcaggact tgcatttttg gtttcaggat attgaagaat taggcaagca
     2041 gtacaggcaa cggggactct atctttttgc tggtccggtt ggaagtggta agacgacctt
     2101 gatgcatgga ttgtccaagt cactctttaa aggacagcaa gttatgtcca tcgaagatcc
     2161 tgtcgaaatc aagcaggacg atatgcttca gttgcagttg aacgaagcaa tcggcctaac
     2221 ctatgaaaat ctaatcaaac tttccttgcg tcatcgacca gatctcttga ttatcggaga
     2281 aattcgtgac agcgagacgg cgcgtgcagt ggtcagagct agtttgacag gtgcgacagt
     2341 cttttcaacc attcacgcca agagtatccg aggtgtttat gagcgtctgc tggagttggg
     2401 tgtgagtgaa gaagaattgg cagttgttct gcaaggagtc tgctaccaga gattaatcgg
     2461 gggaggagga atcgttgact ttgcaaacag agattatcaa gaacaccaag cagccaagtg
     2521 gaatgagcaa attgaccagc ttcttaaaga tggacatatc acaagtcttc aggctgagac
     2581 ggaaaaaatt agctacagct aagcaaaaaa atatcatcac cctatttaac aatctctttt
     2641 ctagcggttt tcatctggtg gagactatct cctttttaga taggagtgct ttgttggaca
     2701 agcagtgtgt gatccagatg cgtgcgggct tgtctcaagg gaaatcattc tcagaaatga
     2761 tggaaagttt gggatgttca agtaccattg tcactcagtt atccctagcc gaagttcatg
     2821 gaaatctcca cctgagtttg ggaaagatag aagaatatct ggacaatctg gctaaggtca
     2881 agaaaaaatt aattgaagta gcgacctatc ctttgatttt gctgggtttt cttctcttaa
     2941 ttatgctggg gctacggaat tacctgctcc cacaactgga tagtagcaat attgccaccc
     3001 aaattatcgg taatctgccc caaatttttc taggcatggt agggcttgtt tccgtgcttg
     3061 cccttttagc actaactttt tataaaagaa gttctaagat gagtgtcttt tctatcttag
     3121 cacgccttcc ctttattgga atctttgtgc agacctactt gacagcctat tatgcacgtg
     3181 aatgggggaa tatgatttca cagggaatgg agctgacgca gatttttcaa atgatgcagg
     3241 aacaaggttc ccagctcttt aaagaaatcg gtcaagatct ggctcaaacc ctgaaaaatg
     3301 gccgtgaatt ttctcagacg ataggaacct atcctttctt taggaaggaa ttgagtctca
     3361 tcatagagta tggggaagtt aagtccaagc tgggtagtga gttggaaatc tatgctgaaa
     3421 aaacttggga agcctttttt acccgagtca accgcaccat gaatttggtg cagccactgg
     3481 tttttatctt tgtggcactg attatcgttt tactttatgc ggcaatgctc atgcccatgt
     3541 atcaaaatat ggaggtaaat ttttaaaatg aaaaaaatga tgacattctt gaaaaaagct
     3601 aaggttaaag cttttacatt ggtggaaatg ttggtggtct tgctgattat cagcgtgctt
     3661 ttcttgctct ttgtacctaa tctgaccaag caaaaagaag cagtcaatga caaaggaaaa
     3721 gcagctgttg ttaaggtggt ggaaagccag gcagaacttt atagcttgga aaagaatgaa
     3781 gatgctagcc taagcaagtt aaaagacgat gggcgaatca cggaagaaca ggctaaagct
     3841 tataaagaat accatgataa aaatggagaa gcaaatcgta aagtcaatga ttaaggcctt
     3901 taccatgctg gaaagtctct tggttttggg tcttgtgagt atccttgcct tgggcttgtc
     3961 cggctctgtt cagtccactt ttgcggcggt agaggaacag attttcttta tggagtttga
     4021 agaactctat cgggaaaccc aaaaacgcag tgtagccagt cagcaaaaga ctagtctgaa
     4081 cttagatggg cagacgctta gcaatggcag tcaaaagttg acagttccta aaggaattca
     4141 ggcaccatca ggccaaagta ttacatttga ccgagctggg ggcaattcgt ccctggctaa
     4201 ggttgaattt cagaccagta aaggagcgat tcgctatcaa ttatatctag gaaatggaaa
     4261 aattaaacgc attaaggaaa caaaaaatta gggcagtgat tttactggaa gcagtagtcg
     4321 ctctagctat ctttgccagc attgcgaccc tccttttggg acaaattcaa aaaaataggc
     4381 aagaggaagc aaaaatcttg caaaaggaag aagtcttgag ggtagctaag atggccctgc
     4441 agacggggca aaatcaggta agcatcaacg gagttgagat tcaggtattt tctagtgaaa
     4501 aaggattgga ggtctaccat ggttcagaac agttgttggc aatcaaagag ccataaggtc
     4561 aaggctttta ccttgttaga atccctactt gccctcattg tcatcagtgg gggattactc
     4621 ctttttcaaa ctatgagtca gctcctcatt tcagaagttc gctaccagca acaaagcgag
     4681 caaaaggagt ggctcttgtt tgtggaccaa cttgaggcag aattagaccg ttcgcagttc
     4741 gaaaaagtag aaggcaatcg cctatacatg aagcaagatg gcaaggacat cgccatcggt
     4801 aagtcaaagt cagacgattt tcgtaaaacc gatgctagtg gacgggggta tcagcctatg
     4861 gtttatggcc tcaaatcagc tcagattaca gaggacaatc aactggttca ttttcgtttc
     4921 cagtttcaaa aaggcttaga aagggagttc atctatcgtg tggaaaaaga aaaaagttaa
     4981 ggcaggtgtt ctcctctacg cagtcaccat agcagccatc tttagtcttt tgttgcaatt
     5041 ttacttgaac cgacaagtcg cccactatca agactatgct ttgaataaag aaaaattggt
     5101 tgcttttgca atggctaaac gaaccaagga taaagccgag caagaaagtg gggaacaggt
     5161 ctttaatcta ggtcaggtaa gctatcaaaa caagaaaaca agcttggtga cgactgttcg
     5221 tacgtctaag agccaatatg agtttctgtt tccttcagtc aaaatcaaag aagagaaaag
     5281 agataaaaag gaagagatag cgaccgattc aagcgaaaaa gtggagaaga aaaaatcaga
     5341 agagaagcct gaaaagaaag agaattccta gtcaattcaa ctataatgcg ttgaatccag
     5401 aatagtccac tatagtttct ataaaattgc tggaaatgga tattaagctc caattcattt
     5461 gtttatatct tatttcagtt tactatactt tgtgctaaac taaagatatg aaacatgatt
     5521 ttaaccacaa agcagaaact ttcgattccc ctaaaaatat cttcctcgca aacttggtat
     5581 gtcaagcagc cgagaaacag attgatcttc tatcagacaa agaaatttta gatttcggtg
     5641 gtggcacggg tctattagcc ttgcccctag cccctagcca agcaggctaa gtcagtcact
     5701 cttgtagaca tttctgagaa aatgttggag caagctcgtt tgaaagtgga gcagcaagca
     5761 atcaagaata tccagttttt ggagcaagat ttaccgaaaa atcccttgga gaaagagttt
     5821 gattgccttg ctgttagtcg ggttcttcat catatgcctg atttggatgc ggctctctca
     5881 ctgtttcatc aacatttgaa ggaagatggg aaactcatca ttgctgattt taccaagaca
     5941 gaagctaatc atcatggatt tgatttagct gaactggaaa acaagctaat tgagcatggt
     6001 ttttcatctg tgcatagtca gattctctat agcgctgaag acctgtttca aggaaatcac
     6061 tcagaattct ttttaatagt agcccaaaaa tcactcgcct agtcagggag tgatttttct
     6121 ataaggatgg aaaaaagaag ggaaatttga taagatagga atatggattt tgaaaaaatt
     6181 gaacaagctt atacctattt actagagaat gtccaagtca tccaaagtga tttggcgacc
     6241 aacttttatg acgccttggt ggagcaaaac agcatctatc tggatggtga aactgagcta
     6301 aaccaggtca aagacaacaa tcaggccctt aagcgtttag cactacgcaa agaagaatgg
     6361 ctcaagacct accagtttct cttgatgaag gctgggcaaa cagaaccctt gcaggccaat
     6421 caccagttta caccggatgc tattgctttg cttttggtgt ttattgtgga agagttgttt
     6481 aaagaggagg aaattactat cctcgaaatg ggttctggga tgggaattct aggcgctact
     6541 ttcttgacct cgcttgataa aaaggtggat tacttgggaa tggaagtgga tgatttactg
     6601 attgatctgg cagctagcat ggcagatgta attggtttgc aggctggctt tgtccaagga
     6661 gatgccgttc gtccacaaat gctcaaagaa agcgatgtgg tcatcagtga cttgcctgtt
     6721 ggctattatc ctgatgatgc cgttgcgtcg cgccatcaag ttgcttctag ccaagaacat
     6781 acttacgccc atcacttgct catggaacaa gggcttaagt acctcaagtc agacggatac
     6841 gctatttttc tagctccgag tgatttgttg accagtcctc aaagtgattt gttaaaagaa
     6901 tggctgaaag aagaggcgag tctggttgct atgattagtc tgcctgaaaa cctctttgct
     6961 aatgccaaac aatctaagac tatttttatc ttacagaaga aaaatgaaat agcagtagag
     7021 ccttttgttt atccacttgc tagcttgcaa gatgcaagtg ttttaatgaa atttaaagaa
     7081 aattttcaaa aatggactca aggtactgaa atataaaata gattttgtta taatagttga
     7141 aaacgcttaa aaaggggtat catgttatga caaaaacaat tgcaatcaat gcaggaagtt
     7201 caagtttgaa atggcaatta tacttaatgc cagaagaaaa agtattggcg aaaggtttga
     7261 ttgaacgtat cggtttgaaa gattcaattt caactgtaaa atttgacggc tgttctgaac
     7321 aacaaatttt ggatattgaa aatcatgcac aagccgttaa aattttattg gatgacttga
     7381 ttcgtttcga tattatcaag gcttatgacg agattacagg tgttggacat cgtgttgttg
     7441 ctggtggaga atatttcaaa gaatcaacag ttgttgaggg agatgtttta gaaaaagttg
     7501 aagagttgag tttgttggct cctctacaca acccggccaa tgcagcaggt gttcgtgcct
     7561 tcaaggaatt gttgccagac attaccagtg tagttgtttt tgatacttcc ttccacacaa
     7621 gtatgccaga gaaagcttat cgctaccctc taccaacaaa atattacaca gaaaacaagg
     7681 ttcgtaaata cggtgctcat ggtacaagtc accagtttgt agcaggagag gctgcaaaac
     7741 tcttgggacg tccattagaa gacttgaagt taattacctg tcatattggt aacggaggct
     7801 caattacagc tgtgaaagcc ggcaaatctg tagacacttc tatggggttc actcctcttg
     7861 gtggtattat gatgggaacg cgtacagggg atattgatcc agctatcatt ccttatttaa
     7921 tgcaatatac agaggatttt aacacaccag aagatatcag tcgtgttctt aaccgtgaat
     7981 caggtctttt gggagtttct gctaattcta gcgatatgcg cgatatagaa gcagctgtag
     8041 cagaagggaa tcacgaggct agcttggctt atgaaatgta tgttgaccgt atccaaaaat
     8101 atatcggtca gtaccttgca gtgctaaatg gagcagatgc cattgttttc acagcaggtg
     8161 tcggtgaaaa tgcagagaat ttccgtcgtg atgtaatctc agggatttcg tggtttggtt
     8221 gtgatgttga tgatgaaaag aatgtctttg gcgttacagg agacatctca acagaggcag
     8281 ctaaaatccg tgtcttggtt attccaacag atgaagaatt agtcattgcc cgtgacgttg
     8341 aacgcttgaa aaaataagtg aaactaaaaa aatattcaat acaaggagtt gggaaagtta
     8401 tttttccagc ttctttttct gatgaaattg tccaaaacct tgctatgatt ggcttttttg
     8461 aaaaatatgg tataatagta gtaatttaat agatggagtt gagttttgaa gaaaaacttt
     8521 cgtgtaaaaa gagagaaaga ttttaaggcg attttcaagg aggggacaag ttttgctaat
     8581 cgcaaatttg tggtctacca attagaaaac cagaaaaacc attttcgagt aggtctatca
     8641 gttagcaaaa aactggggaa tgccgtcact agaaatcaaa ttaagcgacg gattcggcat
     8701 attatccaga atgcaaaagg gagtctggta gaagatgtcg actttgttgt cattgctcga
     8761 aaaggagtcg aaaccttggg atacgcagag atggagaaaa atctactcca cgtattaaaa
     8821 ttatcaaaga tttaccagga aggaaatggg agtgaaaaag aaactaaagt tgactagttt
     8881 gctaggactg tctctgttaa tcatgacagc ctgtgcgact aatggggtaa ctagcgatat
     8941 tacagccgaa tcggctgatt tttggagtaa attggtttac ttctttgcgg aaatcattcg
     9001 ctttttatcg tttgatatta gtatcggagt ggggattatt ctctttacga tcttgattcg
     9061 tacagtcctc ttgccagtct ttcaggtgca aatggtggct tctaggaaaa tgcaggaagc
     9121 tcagccacgc attaaggcgc ttcgagaaca atatccaggt cgagatatgg aaagcagaac
     9181 caaactagag caggaaatgc gtaaagtatt taaagaaatg ggtgtcagac agtcagactc
     9241 tctttggccg attttgattc agatgccggt tattttggcc ctgttccaag ccctatcaag
     9301 agttgacttt ttaaagacag gtcatttctt atggattaac cttggtagtg tggatacaac
     9361 ccttgttctt ccgattttag cagcagtatt caccttttta agtacttggt tgtccaacaa
     9421 agctttgtct gagcgaaatg gcgctacgac tgcgatgatg tatgggattc cagtcttgat
     9481 ttttatcttt gcagtttatg cgccaggtgg agtcgcccta tactggacag tgtctaatgc
     9541 ttatcaagtc ttgcaaacct atttcttgaa taatccattc aagattatcg cagagcgcga
     9601 ggccgtagta caggcacaaa aagatttgga aaatagaaaa agaaaagcca agaaaaaggc
     9661 tcagaaaacg aaataaataa ggaggaatct ggtaatggta gtatttacag gttcaactgt
     9721 tgaagaagca atccagaaag gattgaaaga attagatatt ccaagaatga aggctcatat
     9781 caaagtcatt tctagggaga agaaaggctt tcttggtcta tttggtaaaa aaccagccca
     9841 agtggatatt gaaacgatta gtgaaacgac tgttgtcaaa gcaaatcaac aggtagtaaa
     9901 aggcgttccg aaaaaaatca atgatttgaa cgagcctgtg aagacggtta gtgaagaaac
     9961 cgttgacctt ggtcatgtgg ttgatgctat taaaaaaata gaggaagaag gtcaaggcat
    10021 ttctgatgaa gtcaaggctg aaatcttaaa acatgaaaga catgccagca ctatcttaga
    10081 agaaactggt cacattgaga ttttaaatga acttcaaatc gaggaagcga tgagggaaga
    10141 agcaggcgct gatgaccttg aaactgagca agaccaagct gaaagtcaag aactagaaga
    10201 cttgggcttg aaagttgaaa cgaactttga tattgaacaa gtagctacgg aagtaatggc
    10261 ttatgttcaa acgattattg atgacatgga tgttgaggct acactttcaa atgattataa
    10321 ccgtcgtagc atcaatttgc aaattgatac taacgaacca ggtcgtatta tcggctacca
    10381 tggtaaagtc ttgaaggcct tgcaactgtt ggctcaaaat tatctttaca actgctattc
    10441 aagaaccttc tatatcacta ttaatgtcaa tgattatgtt gaacaccgtg cagaagtctt
    10501 gcagacctat gcgcaaaaat tggcgattcg tgttttagaa gaaggacgta gtcatcaaac
    10561 agatccaatg tcgaatagtg aacgcaagat tatccaccgt attatttcac gtatggatgg
    10621 cgtgaccagt tactctgaag gtgatgagcc aaatcgctat gtcgttgtag atacagaata
    10681 agtaaaatca gggttgacct gattttttgc tagctagagg aggttaaact gatgttgaat
    10741 aagataagag actatctaga cttttctggt ttgcagtacc gtagtcctga taaagcgggg
    10801 gcagagcgag agaagatgct ggcgttccgc cacaaaggac aagaggcccg aaaggctttt
    10861 acagaactgg ccaaagcctt tcaagcaagc catccagaat ggcaactcca acagactagt
    10921 cagtggatga atcaggccca gcgtttgaga ccacattttt gggtttatct acagagagac
    10981 ggacaagtga cagaacctat gatggcctta cgtttgtatg ggacatctac tgactttgga
    11041 atttctttgg aagtcagttt catcgaacgt aagaaggatg agcaaacttt agagaaacag
    11101 gccaagattt tagacatacc aaccgttaaa ggaatttatt atctagccta ctctgatggc
    11161 caaagtcaac ggtgggaggc gaacgaagaa aagcgtcgta ctttacgcga gaaggtgaga
    11221 agtcaagaag ttcgaaaagt tttagtgaag gtagatgttc ctatgacaga aaattcgtct
    11281 gaagaagaaa tcgtagaagg cttattgaag tcttattcta aaattcttcc ctattatcta
    11341 gctacgagaa aataagataa tttgtaaaac atcataaatc atacagtcca agagtgaaca
    11401 gtccgctgtg taattcttgg tctttttgtt tgcgctttcg cattatataa taaacttaca
    11461 aaaacaattc aaaaggagaa caattatgga agtcgtttca agtgttctaa attggttttc
    11521 tagcaatatt ttgcagaatc ccgcattttt cgtaggttta ttggtgttga taggatatgc
    11581 acttttgaaa aaacctgccc atgacgtttt ttcagggttt gttaaagcaa cagtagggta
    11641 tatgttgctt aacgtgggtg ctggtggttt ggttacaacc tttcgtccaa tcttagcagc
    11701 tcttaactac aaattccaaa ttggtgcagc ggttatcgac ccttactttg gacttgctgc
    11761 agcaaacaac aaaattgcag cagagtttcc agattttgtt ggaactgcaa ctacagctct
    11821 attgattggt tttggaataa atatcttgct cgtagctctt cgaaagatta cgaaggtaag
    11881 aaccctcttt attactggtc acatcatggt acaacaagct gcaacagtat ctcttatggt
    11941 tctattctta gtaccacaat tgcgcaatgc ttacggtaca gcagcgattg gtatcatctg
    12001 tggactttac tgggcagtta gttcaaatat gactgttgag gcaactcaac gcttgactgg
    12061 tggtggcgga tttgcgattg gtcaccaaca gcaatttgca atctggtttg tagataaagt
    12121 agcaggacgc tttggtaaga aagaagaaag tttagacaat cttaaattac ctaagttcct
    12181 ctcaatcttc cacgatacag ttgttgcatc tgctaccttg atgctcgtat tcttcggggc
    12241 cattctttta atcttgggtc cagacattat gtctaataaa gaagtcatca cttcaggaac
    12301 tctattcaat cctgctaaac aagatttctt tatgtacatt atccaaacag cctttacctt
    12361 ctcagtttac ttgttcgttt tgatgcaagg tgtccgaatg ttcgtatctg agttaacaaa
    12421 cgctttccaa ggtatttcaa acaaattgtt gccaggttca ttcccagcgg ttgacgttgc
    12481 agcttcttat ggatttggtt ctccaaatgc tgtcttgtca ggatttacct ttggtttgat
    12541 tggtcaattg attacaattg tcttgctcat cgtctttaaa aatccgattc ttattattac
    12601 aggatttgta ccagtgttct ttgacaatgc agccattgcg gtctacgctg ataaacgcgg
    12661 cggatggaaa gcggctgtta tcctttcctt tatatcaggt gtccttcaag ttgctctagg
    12721 agctctttgt gtggcccttc tcgatttggc atcttatggt ggctaccatg gaaatatcga
    12781 ctttgaattc ccatggcttg gatttggata tatcttcaaa taccttggta ttgttggtta
    12841 tgtacttgtg tgtctcttct tgcttgttat tcctcaactt caatttgcca aagcaaaaga
    12901 taaagagaaa tattacaacg gtgaagttca agaagaagct tagtatctag aaaaggagaa
    12961 ataaaatggt taaagtatta gcagcgtgcg gaaatggaat gggttcatca atggttatca
    13021 agatgaaggt tgaaaatgct ctccgtaagc ttaatcaaac agattttaca gtcaattcat
    13081 gcagtgtcgg tgaagctaaa ggtttagcag taggatatga catcgtaatc gcttctcttc
    13141 atttgattca agaattggaa gggcgaacta atgggaagtt aattggactt gataacttga
    13201 tggatgataa agaaatcacc gaaaaactca gtcaagcact acagtaaaag gttggagggg
    13261 gctggacaga aactgagagt tatcgtttct gtccttctcc ctctttaaat aaaggaggca
    13321 gatatgaatt taaaacaagc tttaattgac aatgactcga tccgactagg tttagaggct
    13381 aacgattgga aagaagcagt caaggtagca gtagatccct tgattgaaag tggggcaatt
    13441 ttgccagagt attacgatgc tatcattgaa tcgactgaag agtatgggcc ttactatatc
    13501 ttgatgccag gtatggctat gccccacgct agacctgaag ctggtgtgca aagtgatgcc
    13561 ttttcattaa ttaccttaca aaatcctgtt gtattttcag atgggaaaga ggtatctgtt
    13621 ttgttggcac tagcagcaac aagttcaaaa attcacacaa gtgtagccat tccacaaatt
    13681 attgccctgt ttgaattaga agattctatt gcacgtttac aggcttgcca gactaaagaa
    13741 gatgtcttgg ctatgattga agaatctaag gatagccctt atctcgaagg attggatttg
    13801 gaaagttaga aagaggaata aagaaatgac aaaaagaata cctaatttac aagttgcatt
    13861 agaccattca gacttgcaag gagcgattaa agcagctgtt tctgttggtc aggaagtaga
    13921 tattatcgaa gctggaactg tttgcttgct tcaagttgga agtgaactgg ctgaagtctt
    13981 gcgtagcctt ttcccagata agattattgt ggcagacaca aaatgtgctg atgctggtgg
    14041 aacagttgct aaaaataatg cggttcgtgg agcagactgg atgacttgta tctgttgtgc
    14101 aaccatccct actatggaag cagctctaaa ggctatcaag actgaacgag gagaacgagg
    14161 cgaaatccag atcgagcttt atggcgattg gacttttgaa caagctcagc tttggctaga
    14221 tgcaggtatc tcacaagcta tttatcacca atctcgtgat gctcttcttg ctggtgaaac
    14281 ttggggtgaa aaagacctta ataaggttaa aaaactcatt gacatgggct tccgtgtatc
    14341 tgtaacaggt ggtctagatg tagatactct caaactcttt gaaggtgttg atgtctttac
    14401 ctttatcgca ggtcgtggaa ttacagaggc tgtggatcca gcaggagcag cgcgtgcctt
    14461 caaggatgaa atcaaacgaa tttgggggta aatcatggta cgtccaattg gaatttatga
    14521 aaaggcaacc ccaacacact ttacttggct agaacgttta aattttgcca aggagttagg
    14581 ctttgatttt atcgagatgt ctattgacga acgtgacgag cgtttagcaa gacttgactg
    14641 gagtaaggaa gaacgcttgg aagttgtcaa agaaatctat gaaactggtg ttcgtattcc
    14701 ttctatctgt ttttcaggcc atcgtcgcta cccattggga tcaaaagatt cagttctaga
    14761 ggaaaaatct ctagaactca tgaaaaaatg tatcgaatta gctcaagact tgggagttcg
    14821 tacgattcaa ttagctggtt acgatgttta ctatgaggaa aagtcacccc agacacgcca
    14881 acgttttatc aaaaatttga gaaaagcctg tgactgggct gaagaagctc aggtggtact
    14941 tgctattgaa attatggatg atcctttcat caatagcatc gaaaaatatt tggctataga
    15001 aaaagagatt gactctccct tcctctttgt atatccagat attggtaatg tgtctgcatg
    15061 gcataatgat atctatagtg agttttatct tggtcatcat gccatcgcag ctctccatct
    15121 caaggatact tatgcagtga cagaaagttc aaagggccag ttccgagatg taccttttgg
    15181 gcaaggttgt gtcaaatggg aagaagcttt cgatatttta aaggaaacca attataatgg
    15241 acctttccta atcgaaatgt ggtctgaaaa ttgtgaaaca gtagaagaaa cacgcgcagc
    15301 cattcaagag gcgcaagctt ttctctatcc actcattaag aaagcaggtt tgatgtaaga
    15361 tgaatcaagt aatcaatgct atgcgtaaac gagtctgtga tgccaatcaa tcattgccaa
    15421 aacatggact tgtcaaattt acctggggga atgtatctga agtcaatcgc gaactcggtg
    15481 tcattgttat caaaccatca ggcgtggatt atgacgaatt gacacctgaa aacatggtag
    15541 tgactgatct agatggtaag atcctagaag gggatttaag accatcttcc gacctcccaa
    15601 ctcatgtgca attatataag gcttggtcag aaattggtag tgtggttcac acccattcga
    15661 cagaagctgt tgcttgggct caggcaggtc gtgatattcc tttctacgga acaacccatg
    15721 cagattattt ctacggttca atcccttgcg cccgtagttt gaccaaggac gaagtagaag
    15781 tggcctatga aaaagatact ggcctggtta tcgtagaaga gtttgaacat cgcggactta
    15841 acccggttga agtaccagga attgttgtac gcaatcacgg tccattcacc tggggcaaaa
    15901 atccagagaa tgctgtttat cactctgtcg tactagagga agtatcaaag atgaatcgct
    15961 ttacagaaca aatcaatcca agagttgaac ctgctcccca gtacatacta gaaaaacact
    16021 accaacgtaa acatggacca aatgcttatt atggtcaaaa gtaagaacga tgaaggagga
    16081 gaaaaagata aatttagctc ctctttttac atttgatttt tattgagagt aaagttggag
    16141 ttgaagtaat tttgaaagat tttttagaaa tagcgcttga tatatatggt aaaataaaaa
    16201 gaattgctgt gatatcaata gatttggggg attttttaat atggtactgg ataaggcaag
    16261 ttgtgatttg cttcaatatt tgatggatca agaaacgtcc aaaacgatta tggcgatttc
    16321 gaaagatttg aaagagtcaa gaaggaaaat ttattatcac attgacaaaa tcaatgctgc
    16381 tctggttgac gaggcgcttc acatcattag tattccacga attggtattc acttaacgga
    16441 agagcagaga gatgcttgtt gtaaactatt atcggaagta gattcgtacg attatatcat
    16501 gagtgcgcat gaacgtatga tgataatgtt actatggata ggtatttcta aagaacgtat
    16561 tactattgaa aaattgatag agttaacaga ggtatctagg aatactgttc tcaatgattt
    16621 gaatagtatt cgttatcaac taactttgga acaatatcag gtgaccttgc aagtgagcaa
    16681 gtcacaggga taccaccttc atgcccaccc tcttaataaa attcagtatc ttcaatcgct
    16741 tctatatcat atttttatgg aagaaaatgc cacttttgta tctattttag aagataagat
    16801 gaaagagagg ttagatgatg agtgtttgct ttctgttgaa atgaaccaat tttttaagga
    16861 acaggttcct ttagttgaac aagatttagg gaagaaaata aaccatcatg aaataacttt
    16921 tatgttgcag gttctacctt atttgctgtt aagctgtcat aatgttgaac agtatcaaga
    16981 aagacatcag gatatagaga aagaattttc tttgataaga aaaagaatag agtatcaggt
    17041 gtctaagaaa ttaggagaac ggttgtttca aaagtttgaa atttctttgt caggacttga
    17101 agtttctctt gtagctgttc tcctcctctc ctatcgtaaa gatttggata ttcatgcaga
    17161 aagtgatgat tttcggcaat taaaacttgc tttagaagaa tttatctggt attttgaatc
    17221 acaaatccga atggagattg agaacaagga tgatttgtta cgaaatttga tgatccactg
    17281 taaagccttg ttatttagaa agacttacgg tattttttct aaaaatcctc taacaaaaca
    17341 aattcgatcc aagtatggag aattattttt agtcactaga aaatctgcgg aaattttaga
    17401 aggagcatgg tttattcggc taacagacga tgatattgcc tatttgacga ttcatattgg
    17461 aggattttta aagtatacac catcgtctca aaaaaatatg aaaaaagttt atctcgtttg
    17521 tgatgaaggt gttgcggttt cgagactttt gctgaaacaa tgcaaacttt attttccaaa
    17581 tgagcaaatt gacactgtat ttacaacaga acaatttaag agtgtggaag atattgcaca
    17641 agttgatgta gtgattacta ctaatgatga tttggatagc agatttccga ttttaagggt
    17701 taatcctatc cttgaagcag aagatatttt gaaaatgcta gactatctta aacacaatat
    17761 atttcgtaat aagagcaaaa gtttcagtga aaatctttct agtcttattt cgtcttatat
    17821 tgtagacagc aagttggcta gtaagttcca agaagaggtt caaacactta taaataaaga
    17881 aatagtagtt caagcttttt tggaagatat ttgaaggaca gtccaatgat gaacacaaac
    17941 ctgtgttttt cttggtcttt tttagtgttt tgaagggtgg tatactaatc tcaaagataa
    18001 caattatatc caaaggaggc aacatatgcc aaacgtcaaa gaaattacaa gagagtcatg
    18061 gattttagcc actttcccag agtggggaac atggttgaac gaagaaatcg aagaagaagt
    18121 cgtacctgaa ggcaactttg ccatgtggtg gctaggcaac tgtggtactt ggattaagac
    18181 accagctggt gctaacgttg tcatggacct ttggtcaaac cgtggaaaat caaccaaaaa
    18241 agtgaaagat atggttcgtg ggcaccaaat ggcaaatatg gcaggtgttc gtaagttgca
    18301 accaaacttg cgtgttcagc caatggttat cgatccattt gctatcaacg aactagacta
    18361 ttacttagtt tcacacttcc acagtgatca tatcgaccca tacacagctg cagcaattct
    18421 caacaatcct aagttagagc atgttaagtt tatcggtcct taccactgtg gacgaatctg
    18481 ggaaggatgg ggtgttccaa aagaacgtat catcgttgtt aaaccaggtg acactatcga
    18541 attaaaagat atgaagattc atgcagtaga atcatttgac cgtacttgct tggtaactct
    18601 cccagtgaac ggtgctgatg agacaggcgg tgaacttgct ggcttggctg ttacagatga
    18661 agaaatggct caaaaggctg ttaactatat ctttgaaaca ccaggtggaa ccatctatca
    18721 tggtgcagat tctcacttct caaactattt tgcaaaacat ggtaaagact ttaaaattga
    18781 tgttgctttg aataactatg gtgaaaatcc ggtaggtatc caagacaaaa tgacatctat
    18841 cgaccttctt cgtatggcag aaaatctgcg taccaaagtc attatcccag ttcactatga
    18901 tatctggtct aacttcatgg cttctactaa tgagattcta gaactttgga aaatgcgaaa
    18961 agatcgcttg caatacgatt tccatccatt tatctgggaa gttggcggta agtacactta
    19021 tcctcaagat caacacttag tagaatacca tcatccacgt ggttttgatg attgttttga
    19081 acaagactct aacattcaat ttaaagcttt gctataatat aaaaatattc tttggaggtt
    19141 atccgtatgt tgcatgatac ggataatttt catataatag taaaatagaa tgtgtgattc
    19201 aataatcacc tcaaatagaa aggaaattct atgtcaaatc tatctgttaa tgcaattcgt
    19261 tttctaggta ttgacgccat taataaagcc aactcaggtc atccaggtgt ggttatggga
    19321 gcggctccga tggcttacag cctctttaca aaacaacttc atatcaatcc agctcaacca
    19381 aactggatta accgcgaccg ctttattctt tcagcaggtc atggctcaat gctcctttat
    19441 gctcttcttc acctttctgg ttttgaagat gtcagcatgg atgagattaa gagcttccgt
    19501 caatggggtt caaaaacacc aggtcaccca gaatttggtc atacggcagg gattgatgct
    19561 acgacaggtc ctctagggca agggatttca actgctactg gttttgccca agcagaacgt
    19621 ttcttggcag ccaaatataa ccgtgaaggc tacaatatct ttgaccacta tacttacgtt
    19681 atctgtggag acggagactt gatggaaggt gtctcaagcg aggcagcttc atacgcaggc
    19741 ttgcaaaaac ttgataagtt ggttgttctt tatgattcaa atgatatcaa cttggatggt
    19801 gagacaaagg attcctttac agaaagtgtt cgtgaccgtt acaatgccta cggttggcat
    19861 actgccttgg ttgaaaatgg aacagacttg gaagccatcc atgctgctat cgaaacagca
    19921 aaagcttcag gcaagccatc tttgattgaa gtgaagacgg ttattggata cggttctcca
    19981 aacaaacaag gaactaatgc tgtacacggc gcccctcttg gagcagatga aactgcatca
    20041 actcgccaag ccctcggttg ggactacgaa ccatttgaaa ttccagaaca agtatatgct
    20101 gatttcaaag aacatgttgc agaccgtggc gcatcagctt atcaagcttg gactaaatta
    20161 gttgcagatt ataaagaagc tcatccagaa ctggctgcag aagtagaggc catcatcgac
    20221 ggacgtgatc cagtcgaagt gactccagca gacttcccag ctttagaaaa tggtttttct
    20281 caagcaactc gtaattcaag tcaagatgcc ttgaatgttg tggcagctaa attaccaacc
    20341 ttcctaggtg gatcagctga ccttgctcac tcaaacatga cttatatcaa gacggatgga
    20401 cttcaagacg ataccaatcg cttgaatcgt aacattcagt ttggtgttcg tgaatttgca
    20461 atgggaacaa tcttgaacgg gatggccctt catggtggac ttcgtgtata cggtggaact
    20521 ttcttcgtct tctctgacta tgtgaaggca gctgtccgct tgtcagcctt acaaggactt
    20581 cctgtgactt atgtctttac ccatgattca atcgcagttg gggaagatgg tccgactcac
    20641 gaaccagttg agcatttagc aggtcttcgt gctatgccaa atctaaatgt tttccgtcca
    20701 gcagatgcgc gtgaaactca agcagcttgg taccttgcag tgacaagtga gaaaacacca
    20761 actgcccttg tcttgacacg tcaaaacttg actgttgaag atggaacaga cttcgacaag
    20821 gttgctaaag gtgcttatgt tgtatatgaa aatgcagccg actttgatac catcttgatt
    20881 gcgacaggtt cagaggttaa tcttgctgtc tcagctgcta aagaattggc tagtcaaggc
    20941 gaaaaaatcc gcgtagtcag catgccatct acagatgtct ttgataaaca agatgcagct
    21001 tacaaggaag aaattcttcc aaatgcagtc cgccgtcgtg ttgcagtcga aatgggtgca
    21061 agtcaaaact ggtacaaata tgttggtctc gatggtgccg ttctaggtat tgataccttc
    21121 ggagcctctg ccccagcacc aaaagtattg gcagaatatg gctttactgt agaaaatctt
    21181 gtaaaaattg ttcgaaactt gaaataatcc taaaaatcag ggcgtaagct ctggtttttc
    21241 ttaccagaaa agtaaggtac aatcttgtaa aagtagctga aatttgatat agtagtccta
    21301 tgtaaaagac aaaggagaaa acaatgaatc caaatattac ttttttaatc atgcttgtag
    21361 gtatgatggc cttgatgttc tttatgcaac gttctcaaaa gaaacaagct caaaagcgta
    21421 tggaaagctt aaataaacta caaaaaggct atgaagtgat tacaatcggt ggactttatg
    21481 gaacagtcga tgaagtagat acggagaagg gaacaatagt tcttgacgta gatggagttt
    21541 acttgacttt tgaactagct gctatcaaga cagtattacc gctgaaagaa acagcttcac
    21601 tagaaggcgc aattgaaaaa taagacggga tcacgaactc ccgtttttct ataaaagaaa
    21661 ggaaatggga tgaaaaaatt agtctttgtc tgtctgggaa atatttgccg tagccctatg
    21721 gccgagtttg ttatgaaatc aatgacagat aactacgaaa tccaaagtcg agcaacttcc
    21781 tcttgggaac atggcaatcc gattcataag gggactcagg gaatttttca acagtatgag
    21841 attccttatg acaagaacaa gacatcgctt cagattagta aggaagattt tgaagccttt
    21901 gattatatta tcggaatgga cgcttcaaat atttctgact tacgtcagat gtgtccagta
    21961 gactgtcaag ataagattta ctcattttca tctgaaagtg ttccagaccc ttggtataca
    22021 ggagattttg aagaaaccta tcgacgtgtt caagagggct gtcaagcttg gttagaacgt
    22081 ttagaaaagg agagttaagg tggaaaatct tacgaatttt tacgaaaagt atcgtgtcta
    22141 tctgactcgt ccacgtttag agcttttggc agtagttacc attgttttct gtgctgtact
    22201 cgtctttttt ctaaatattc caggaaaagg tgtcttaaaa ctcgataatg gaacgattgt
    22261 ttatgatggc agtcttgtcc gtggtaaaat gaatggtcaa ggtaccatta ccttccaaaa
    22321 tggagaccaa tatacaggtg gcttcaacaa tggagccttc aacggaaaag gtacctttca
    22381 atctaaagaa ggctggacct acgaaggtga ttttgtaaat ggtcaggctg aaggaaaagg
    22441 gaaactaaca acagaacaag aagtcgttta tgaaggaact tttaaacaag gcgtttttca
    22501 acaaaaataa agcctcctta tccaaaggag gtattattag aaccacaagg taagcgctta
    22561 cctgtaaatc cctttctttc caaatccctc ttccaagcaa gtttgtgaaa taaaaaatat
    22621 ttgaaataaa tttcacaaac ttcaaagata aaacctgata agaaaagaaa atgagaaaag
    22681 tttcacaaga gtttaaaaat tctttgtgaa atgtttatga aactgtttac aaagttgaaa
    22741 taatgcgtta taataaactt gtgaaaaaat taacaaagga tatcgttcct tgaaagctat
    22801 ggaggaaaat atggctgata aaaaaactgt gacaccagag gaaaagaaac tcgttgctga
    22861 aaaacacgta gatgagttgg ttcaaaaagc tctagttgcc cttgaagaaa tgcgtaaatt
    22921 ggatcaagag caagttgact acatcgttgc caaagcatca gtagcagctt tggatgccca
    22981 cggagaattg gctttacatg cctttgaaga aacaggacgt ggtgtatttg aagacaaagc
    23041 aactaagaac ttgtttgcct gtgaacacgt agtaaacaac atgcgccaca ctaagacagt
    23101 tggcgttatc gaagaagacg atgtaacagg attgactctt attgctgaac cagttggtgt
    23161 tgtttgtggt attactccaa caacaaaccc aacatcaaca gcaattttca aatcattgat
    23221 ttcattgaag acacgtaacc caatcgtctt tgccttccat ccatcagcac aagaatcatc
    23281 tgctcatgca gctcgtatcg tccgcgatgc agctatcgca gctggtgctc ctgaaaactg
    23341 tgtgcaatgg attactcaac catctatgga agcaacaagt gcccttatga accacgaagg
    23401 ggttgcgaca atccttgcaa caggtggtaa tgccatggtt aaggcggctt attcatgtgg
    23461 taaaccagct cttggggtag gtgccggaaa cgttccagct tatgttgaaa aatcagcaaa
    23521 cattcgtcaa gcagcacacg atatcgtcat gtctaaatca tttgataacg gtatggtctg
    23581 tgcatctgaa caagcagtta tcattgataa agaaatttac gatgaatttg tagcagagtt
    23641 caaatcttac cacacttact ttgtaaacaa aaaagaaaaa gctcttcttg aagagttctg
    23701 cttcggcgtc aaagcaaaca gcaaaaactg tgctggtgca aaattgaacg ctgacatcgt
    23761 tggtaaacca gcaacttgga ttgcagaaca agcaggattt acagttccag aaggaacaaa
    23821 cattcttgct gcagaatgta aagaagttgg cgaaaatgag ccattgactc gtgaaaaatt
    23881 gtcaccagtt attgcagttt tgaaatctga aagccgtgaa gatggtatta ctaaggctcg
    23941 tcaaatggtt gaatttaacg gtcttggaca ctcagcagct atccacacag ctgacgaaga
    24001 attgactaaa gaatttggta aagctgttaa agctattcgt gttatctgta actcaccttc
    24061 tacttttggt ggtatcgggg acgtttacaa tgccttcttg ccatcattga cacttggatg
    24121 tggttcttac ggacgcaact cagttgggga taacgttagt gccattaacc tcttgaatat
    24181 caaaaaagtc ggaagacgga gaaataacat gcaatggatg aaacttcctt caaaaacata
    24241 ctttgaacgt gattcaattc aataccttca aaaatgtcgt gacgttgaac gtgtcatgat
    24301 cgttactgac catgccatgg tagagcttgg tttccttgat cgtatcatcg aacaactgga
    24361 ccttcgtcgc aataaggttg tttaccaaat ctttgcggat gtagaaccgg atccagatat
    24421 cacaactgta aaccgtggta ctgagattat gcgtgccttc aaaccagata ccatcatcgc
    24481 actcggtggt gggtctccaa tggatgctgc caaagtaatg tggctcttct acgagcaacc
    24541 agaagtggac ttccgtgacc ttgtccaaaa attcatggat atccgtaaac gtgccttcaa
    24601 gttcccattg cttggtaaga agactaaatt catcgcgatt ccaactacat ctggtacagg
    24661 atctgaagta acaccatttg ccgttatctc tgataaagca aacaaccgta aatacccaat
    24721 cgctgactac tcattgacac caactgtggc aatcgtagat cctgctttgg tattgacagt
    24781 tccaggattt gttgctgctg atactggtat ggacgtattg actcacgcga cagaagcata
    24841 cgtatcacaa atggctagtg actacactga tggtttagca cttcaagcca ttaaattggt
    24901 ctttgaaaat ctcgaaagct cagttaagaa tgcagacttc cactcacgtg agaaaatgca
    24961 taacgcttca acaatcgctg gtatggcctt tgccaatgcc ttcctaggta tttctcactc
    25021 aatggcccat aagattggtg cgcaattcca cacaatccac ggtcgtacaa atgctatctt
    25081 gcttccatac gttatccgtt acaacggtac acgtccagct aagacagcaa catggcctaa
    25141 gtacaactac taccgtgcag atgaaaaata ccaagatatc gcacgcatgc ttggacttcc
    25201 agcttctact ccagaagaag gggttgaatc ttacgcaaaa gctgtctacg aactcggtga
    25261 acgtattggg atccaaatga attttagaga ccaaggaatt gacgaaaaag aatggaaaga
    25321 acattctcgt gaattagcct tcctggctta tgaagaccaa tgttcaccag ctaacccacg
    25381 tcttccaatg gtagaccata tgcaagaaat catcgaagat gcatactatg gctacaaaga
    25441 aagaccagga cgccgtaaat aattgtttat cagtctagaa gcaagacaaa aactcaattt
    25501 gagggaaaga tccagtaatt tttctatgat aaaaggcatc ctatcaaggt ttttgaacac
    25561 ctgataggat gcctttttat gatattgagg cctttttgcc ctttttgaaa aactagaata
    25621 gaaacaaaat atataataga ttgaaactag agtagtacac atctgcttct aaaacattgt
    25681 tagaattcga tttgactgtc ctgatcaatt tgtcctgttc ttatttcatt ttaatatata
    25741 aaaaatatag tatagtagac tgaatctaaa atagtacgaa acaattgcta aaacatttat
    25801 agaaattaat tttacttttc tgatagagtt gttcacatct tatttcaatt cactatagtt
    25861 taatttaaga gtagtattta ctaaggccca attaaaatca aagagcaaac tagaaaacga
    25921 gtgccattca gctcaaaaca ctgatttgag attgcagata agactagccc cctcattaac
    25981 agatttacga taaaacgatg acaaggtgtg ttgctttttg atttctaaag agtataatga
    26041 tagatctcta taaaataagt gcgaaggaaa tgagctttta tagtcctttc gttttaaaat
    26101 actatctcag atattcttat atcgacaaga agtttttgag tcattccctc atcatacata
    26161 ttaaataaat agtggctcat tcaatttttt actagaataa taagctagta tagtaaactg
    26221 aaataagata taaacaaata aattggagct taacatctat ttccagcaat tttttagaaa
    26281 ctgcagtgga ctattctaaa ttcaacacat tataaaaact agagtaaaag aaaaggattg
    26341 gatcttgtgt aatgcaggat ccaatccttt caatcatttt gtccaacttt tggaggttcc
    26401 tacaatgtag ccgtcattaa taaagacaga tgggaacgac agtgttccta tttattttga
    26461 tagagatcga tgaattcttt agatagcaac tgaataatct ctgttgaagc catttggtct
    26521 tctgcatgca taaatagcaa ggagaatcct attttttctc cagtagcttc tttttgtatg
    26581 agattagagt gaatcttgtg cgcttctact aaggagtctt ccgcttcttc aactttaatt
    26641 ttcgcttctt ttaaatttcc tgccttagct agttggatgg cttcaataaa ggatgatttg
    26701 gctgctccac tattggcaat gagctgaaaa cagatatatt ccatttcttc tgtcatctta
    26761 tttctcctat ccatgcaagt gcttgttcca gaacttttgc tccattcatc attccgtaat
    26821 cccgcatatc aatggtatct acagggatat ttcctgcaat ttctttcaca gcaagtaact
    26881 cataacgaat ttgtggccca attagaatga catctgcttc atggatattc tttttagctt
    26941 ctgtcattga ttttgcttgg atagaaattt caatcccacg ttcagtcgca ctttgttgca
    27001 tttttttaac aagcatactt gtcgacattc ccgcattaca tactaataaa atttgtttca
    27061 taatcttaac cttccatttc ttgctcaaca actttgtcat taactttgat aaatggaatg
    27121 tatagaagaa ctccaagtgc aaagatgatg aattgaacta gaactgctct cacgtcccct
    27181 gctgttgcta accatgcatt taagaatact ggtgtagtcc aaggaacttg tataaatgca
    27241 ggactcatga atcctgtaac tgttgctaag tagctgatta aaataccaag gactggaact
    27301 gtgataaatg gaatagctaa tgaaatgtta taaacgattg ggtaaccgaa taatactggt
    27361 tcattgatat tgaagatacc aggtccaaaa gataatttag ccacgttttt agagacagca
    27421 ttgcgactca ctaagaatgt tgctattaat aaacataatg tagatccact accacccatt
    27481 aaagcgaatg tttgtatttg tgataggttg atgatgtgtg gaatggcttg tccattattt
    27541 gctgcagtga tgttttcagt aatgttaatt aatagtaatg gttctaggat ggcactgtaa
    27601 ataactgctt ggtgaatacc aaatagccat aacatatttc ctaaagagta aataataatg
    27661 accccgatta agcttgtacc aatatgacga attggttctt gaataaagat tgtaatgatt
    27721 gagattaagt tcattccagt tatattgaat aataatgctg aaacaacccc aaataaggag
    27781 atgacggtca tgactggaag taatacgcta aatgatctac taacagctgg tggaatattt
    27841 tcaccaaggt tcatttgtaa agctttaacg tttgataatt caatgaataa ttctgttgca
    27901 ataatcgcta cgataacccc ggcgaacatt gcgcctgtac ctgtgttgtt gaatgaaaga
    27961 acacctgaaa tgtttaccgc atcttttgct ccgtcaggaa ctacagaaac tgtatttggc
    28021 atcatcacaa ttaaagaaac taatgatagc attgatgctg ctaacgggtt ttcgaaatct
    28081 ctgtttttag ctaagaaata accaaccatt acagcaataa tcatacctga aatacttaaa
    28141 gtaccgtttg caattgttat tccccaatat tggaatcttg ttaatgtatc cccttggaaa
    28201 atccacttaa ataccgtgtt gttcaaaaga acgattaaac ctgccaaaat atataatggc
    28261 attactgtta cgaatgcatc tcttagggtt tttaaatgaa tttggttccc tagtttacca
    28321 gcaaaggtgg caaattgatc tataaatttt gagtttttca tctgaatatc tcctctcttt
    28381 actcctcaat ttctacttca aaaccgttat tgtcacttac tttgcgatac catcttcctg
    28441 agctcttgat ggttctcttt tgcgtttcta aatcaacgga gataaatccg taacgattct
    28501 tatatgcatt attccaagac cagcaatcaa atgcggtcca agcgtggtat ccaaaacagt
    28561 gacttccctc ttcaatggct ttatgtagcc atcttaaatg ttcttcataa aattcaatac
    28621 gatacacgtc atcgataact ccattttcac cgataaaccg tgcttcgttt tcaacaccca
    28681 ttccgttttc actgataaac catggaatat tatcatattc ttccttcaca atcatagcaa
    28741 tatcataaat ggctttcgga aaaatttccc aaccacgata tggattcatg cgacgctccg
    28801 gccattcata ctctttgaag tattggtctg gcatccaggg cgtctgatat tcctcaggat
    28861 ttgcttgtgc ttgaacacgt tttggatggt agtagtttac tccaagaaaa tcaaccgtat
    28921 ttgatttcat cagttgaagc tctttttcgg tatgactcca taacacgcca tctctctcta
    28981 gctgttttac caatctttct gggaaagttc ctttaacagc tggattcaag aagactttgt
    29041 taaagaagtc atctgtaaat cgacttgctt ctaagtcttc tggagaatta cttcttggat
    29101 aagcaggtgt caagtttaaa ataatcccaa tctttccatc aagtcctaat gagcgatata
    29161 gttgaatcac ttttgcacta gcaaggttta gattatagat gatttgtacg gcctcttttc
    29221 cctttccttt tagatttgga taatggaaag catataagta tcctgcttct ggaatgacca
    29281 ttggctcatt gaaagttgtc cagtaatgaa ccttatctcc aaagcatgtg aaagcagtct
    29341 tggcaaactt cacgaataac tccactacat gtttgctttc ccaaccaccg tatttttgaa
    29401 gaagttccac tggtaaatca aaatgatgta aattcatcac aagatccatc tggttctttt
    29461 tagcttcttc aatgatggca ttgtagaaag caataccttt tggatcaggc tcacctgtct
    29521 ctaaattctt gatgagtcga ctccattgga tggaagtgcg gaaagaatta actccaattt
    29581 ccttcatcaa gtggaaatct tcggtgtaag tatgaaaaaa gttactggct acaagaggtc
    29641 cgacattatc gaaaaaatct tctggatgcg ttttgaacca gtagtccatc acattttcat
    29701 gtacttttcc atattgacct tctgtctgag gtccgctaga agcagccccc caccaaaaca
    29761 gattaggaaa tactaacttt tttttcatgc tcaacctcct ttctattatt ctatacataa
    29821 agtatagcat aattttaaaa tttgtctaga catttttaaa aattgtttat acatatcttg
    29881 tgtttgcctc atttcttgaa ctttgttata ctactattag aatattatag agagaaccag
    29941 attaaatgag tacaaaatat ttatttattt acaatgagat tcgtgaaaag attctttgta
    30001 ataaatatac catgaacgaa caattgcctg atgaaatgac attagctaaa cagtttgcct
    30061 gtagtcgaat gacgatcaaa aaagctttag acttgttagt ttctgagggc ttaattttta
    30121 gaaaacgtgg gcagggaacc tttgttctct ctcgtggcag ctcaaaaaga aaattaatcg
    30181 ttccagaaag agatatccgg ggactgacaa aaatatctga agatgctcat tctacaattg
    30241 actcgaggat tattcacttc aaattagaat ttgcaaatga atttttagca gaaaaactac
    30301 aggtcgcttt gcagagtcca gtttataata tttaccgcct gcgtattatt gacggtaaac
    30361 cttatgttct ggaacaaact tatatgagta ccgatgttat tccaggtatt actgaagata
    30421 ttttacaaaa atcgatttac aattacattg aaggaaagtt aggattgcat attgccagtg
    30481 ctacaaaaat cttgcgagct tcttctagtt cagaaaatga gcaacattac ttgcagctcc
    30541 ttccaacgga accggtattt gaagtagaac aagtggctta tttggataac ggaactccgt
    30601 ttgagtactc gattagtcgt catcgctatg atttatttga atttaattct tttgcattac
    30661 gacattcctc ctaggagaaa atgtgaaaat gaagccaatc ttttacagac tctagtttaa
    30721 gaaaaattta aaacagggca agaaggtccc atctatgctt aaatggtttc tcttttctaa
    30781 ataagatggc tttaaaagag tgatcgtttt atccatcatg ttgaaaaata tcttcgtata
    30841 gcttatagag taggtactga aattgttcac ctgatctact tcttatagtt atttagtttt
    30901 aaatagtgtt tcaaacattc ttacactgac gagaagtttt tgagtctttt cttgtaacac
    30961 atatagtata ctgaggttag aatagtagac tgtgacttct aacaaattgc tagaaatgaa
    31021 tttcaatctc ccaatttatt tgttcatatc ttcttttaat atattaaata aattctgaat
    31081 cataatcatt taaaaaaatt ttatttttta tttttcatta cgaataatat agatgaaggg
    31141 gaaagagtat gaaaacagaa ctgtttcttt tgctattagt tcaaaaggag aaaaaatgaa
    31201 agtagaaaat atttcgtata gggtggatca tcgtatattg tttgataata tttcttttga
    31261 tacttcgagt tcaggcgtga cattaattac tggtaaaaat ggtacaggaa agtcaacttt
    31321 actatagtag attgaaacta gaatagtaca catctacttc taaaatattg ttagaaattg
    31381 atttgactat cctgatctat ttgtcctgtt cttatttcat ttcactatat ctcaaattga
    31441 gtatgacgaa gtgcgctccc atgtcctggg aacgcacttt cttcatattt ttcatattct
    31501 tgaatccatc gataaagact attgggatga atttttaaag ttgaactaat catttttaca
    31561 ggatgagatt tacagcagag agtttgaagg ctttatcaaa ggtttttctt ggcataatga
    31621 cttttcctcg tttccactta attttgtgtc tactttatta taccaagtcc acccttaagt
    31681 tagataataa atctaactta aggaagctag aaggatgaga atccaggtgg tcaagagtcc
    31741 caaacttaag ctgatgggga cacccagaat aatttgcttt ttgaaggcaa ggccacgttc
    31801 ctctatattg ggaagtgaga gttgaatgag agaaccagct gatgaaaagg gtgagatatt
    31861 agtagataga gcgccaataa cggtggctgt tgtgagtaag tgaatatcaa tctgaggatt
    31921 ttgagcactg atgatagcaa tgatgggaaa gagggctgga gctacaacgg atagggtgga
    31981 actaaagagt gacatcactc cggctatcac acaaaagaac agaggtaacc agaaatgagg
    32041 aatggttgtt gtcatgaggt gccctatcag tgtgactaaa cctgacttga ccgctagaga
    32101 cattagtaag ctcatgccgc agagcatgat aattgtagcc cagggaacct tagctaaaat
    32161 ggcttcttgc ttccctaatt tgagccttaa ggcgaggcag accatgagta ttgagacaaa
    32221 gccaatatca aatgtttttt gataagtagc tatccaggcg atgtttggga aaatgagatg
    32281 caacaaggga aaaagccaaa ccaaaaccat actgctgatc atgagcaagg tggtttgtct
    32341 ttgaaccttg ctgaggagtg gtggttggtc aatagtcaag gatgagtttg ttcttccctt
    32401 actatagtga ctgtaacagg ataataaaag caagacgatg agtgggtaga taatgctgac
    32461 gataaagata tgattgccaa gtgaaaaagc ttgctcctcc catcccattt gcttaaacag
    32521 gccttgaaag acaatgcctg agctactggt tatcaaatta gcccctcctg aagctcccca
    32581 attgacggct tgagctccaa tcaaagggtg tttgtccgct ttttgacaga gggtaatcgc
    32641 tagaggacag caaacggcca tagtagtgaa aaatccagca cctaaagcag acaaaagggt
    32701 tgccatcagg tataaaatca tgtagagggc gttagggtgg gtgcgtgtgc ggtagagaat
    32761 gtgttgagcc aaaacatcaa gagtaccgtt agttgttgca acgttataaa agagagagac
    32821 gctaaaaatg gtaaaaaaga gtgaggttgg ccaaaaatga agaagttctt tggggcttaa
    32881 tcccatgaga gtggttgcga tgaggtaaga aaaagcaata gccagcaggc caatattgat
    32941 tttggtgcgg taaccaattc caatggctag agcaatggcg ctaatcatta ttaaatgaat
    33001 cattgaattg tcctttcagt tagaatatgg aaataggttg gcaattttgg cgctcaaaag
    33061 accacctgtt tcctattggt acttgactat tatacacaaa aaaaatacaa ttgtcttgac
    33121 aattgtattg acacttgtta gaattaaaaa tgaggtattc aggcttgtga tttcctatgg
    33181 aagttaatag taattgcctc tagtgcttac aagtgatatt aaaaatagag gacttagtga
    33241 tgtcaatcat ttcaactgat ttaacccctt ttcaaataga tgatacattg aaagcagcct
    33301 tgcgagaaga tgttcattcc gaagattaca gtaccaatgc catttttgat catcatggcc
    33361 aagccaaggt gtcgcttttt gccaaggaag ctggtgtttt agcgggacta accgtttttc
    33421 aaagggtttt taccctattt gatgccgagg tgaccttcca gaatcctcat caatttaagg
    33481 atggggatcg tttgactagt ggcgatttgg ttttagaaat cataggctcg gtgagaagtc
    33541 tcttaacatg tgaacgcgtt gccttgaatt ttttacaaca tttatcaggg attgcttcga
    33601 tgacagctgc ttatgtagaa gccttaggcg atgattgcat taaggtattt gatactcgaa
    33661 aaactactcc taatttacgt ctttttgaga aatatgccgt gagagttggc ggtggctata
    33721 atcatcgctt taatttatca gatgctatca tgctaaaaga caatcacatt gcggcagtag
    33781 gtagtgttca aaaggcaatt gctcaagcgc gtgcctatgc cccttttgtg aaaatggtcg
    33841 aggtggaagt ggaaagcctt gctgctgccg aagaagctgc ggcggcgggt gctgatatta
    33901 tcatgttgga taatatgtca ttggaacaga ttgaacaggc cattacccta attgcaggac
    33961 gttctcggat tgaatgttct ggaaatattg atatgaccac tattagccgt tttcgtggtt
    34021 tagcgattga ttacgtctcc agtggtagtt taacccatag tgctaagagt cttgattttt
    34081 ccatgaaggg tttaacctac cttgatgtct aagttgtaaa ataaactaac tttttaaagg
    34141 atgtctttcc tctagaacga gttttatgtc agatagttta aacgcctctt caaatatagt
    34201 aaaatgaacc aaaaatagta ca
//
LOCUS       DAVAGB010000019        34173 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVAGB010000019 DAVAGB010000000
VERSION     DAVAGB010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34173
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.019"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(58..1068)
                     /locus_tag="VQO19_001038"
     CDS             complement(58..1068)
                     /locus_tag="VQO19_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HET1349321.1"
                     /translation="MSFLSKNGAGILVCLLISILSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDVGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNTLESATIVKLT
                     RTLAIIPITLFLSYWQSREQKNKQGLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            1217..2386
                     /locus_tag="VQO19_001039"
     CDS             1217..2386
                     /locus_tag="VQO19_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET1349322.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2383..3153
                     /gene="recO"
                     /locus_tag="VQO19_001040"
     CDS             2383..3153
                     /gene="recO"
                     /locus_tag="VQO19_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HET1349323.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3150..4142
                     /gene="plsX"
                     /locus_tag="VQO19_001041"
     CDS             3150..4142
                     /gene="plsX"
                     /locus_tag="VQO19_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HET1349324.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVRLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTFPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            4148..4381
                     /locus_tag="VQO19_001042"
     CDS             4148..4381
                     /locus_tag="VQO19_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET1349325.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            4427..4717
                     /locus_tag="VQO19_001043"
                     /pseudo
     CDS             4427..4717
                     /locus_tag="VQO19_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            4920..5078
                     /locus_tag="VQO19_001044"
     CDS             4920..5078
                     /locus_tag="VQO19_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin class II family protein"
                     /protein_id="HET1349326.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAILGGV
                     AYAATCWW"
     gene            5797..7950
                     /locus_tag="VQO19_001045"
     CDS             5797..7950
                     /locus_tag="VQO19_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HET1349327.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKDQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTLINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAALSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGEMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            7963..9312
                     /locus_tag="VQO19_001046"
     CDS             7963..9312
                     /locus_tag="VQO19_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HET1349328.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTVKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAEINLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            9482..10189
                     /locus_tag="VQO19_001047"
     CDS             9482..10189
                     /locus_tag="VQO19_001047"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HET1349329.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            10391..14116
                     /locus_tag="VQO19_001048"
     CDS             10391..14116
                     /locus_tag="VQO19_001048"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HET1349330.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSDRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLA
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFTQFEAIQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKVG
                     QTKADFTLTVNRVKLDGHKLDSAFQGTLEEVYPTEFTRAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEAANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            14209..15651
                     /locus_tag="VQO19_001049"
     CDS             14209..15651
                     /locus_tag="VQO19_001049"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HET1349331.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            15688..16710
                     /locus_tag="VQO19_001050"
     CDS             15688..16710
                     /locus_tag="VQO19_001050"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HET1349332.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKTLEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            16707..17252
                     /gene="purN"
                     /locus_tag="VQO19_001051"
     CDS             16707..17252
                     /gene="purN"
                     /locus_tag="VQO19_001051"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HET1349333.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            17336..17845
                     /locus_tag="VQO19_001052"
     CDS             17336..17845
                     /locus_tag="VQO19_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET1349334.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLIFFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEY
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            17870..19417
                     /gene="purH"
                     /locus_tag="VQO19_001053"
     CDS             17870..19417
                     /gene="purH"
                     /locus_tag="VQO19_001053"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HET1349335.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLGSDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            19539..20801
                     /gene="purD"
                     /locus_tag="VQO19_001054"
     CDS             19539..20801
                     /gene="purD"
                     /locus_tag="VQO19_001054"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HET1349336.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHYKLIDFAKANDIAWTFIGPDDALAAGIVDDFHAAGLKAFGPTRLAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAADTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELYQQKIEGLFYRTDIGSKAIK"
     gene            21203..21691
                     /gene="purE"
                     /locus_tag="VQO19_001055"
     CDS             21203..21691
                     /gene="purE"
                     /locus_tag="VQO19_001055"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HET1349337.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEAYSRGIKVIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            21678..22769
                     /gene="purK"
                     /locus_tag="VQO19_001056"
     CDS             21678..22769
                     /gene="purK"
                     /locus_tag="VQO19_001056"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HET1349338.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPVSRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEVD
                     LEAAYALAESADCVLEEFVNFALEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEKYVAENPSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            22779..23006
                     /locus_tag="VQO19_001057"
     CDS             22779..23006
                     /locus_tag="VQO19_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HET1349339.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            23069..24367
                     /gene="purB"
                     /locus_tag="VQO19_001058"
     CDS             23069..24367
                     /gene="purB"
                     /locus_tag="VQO19_001058"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HET1349340.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(24422..28360)
                     /gene="strH"
                     /locus_tag="VQO19_001059"
     CDS             complement(24422..28360)
                     /gene="strH"
                     /locus_tag="VQO19_001059"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET1349341.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEKTPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYDSDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSHLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLDQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYVIGNHKQDEAY
                     PLSKAVENSGKVPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGSPVTHKGDESG
                     LAPTTEVKPRLDIQEEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(28676..29392)
                     /locus_tag="VQO19_001060"
     CDS             complement(28676..29392)
                     /locus_tag="VQO19_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET1349342.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            29739..31526
                     /locus_tag="VQO19_001061"
     CDS             29739..31526
                     /locus_tag="VQO19_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HET1349343.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFDGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLNNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            31523..31999
                     /locus_tag="VQO19_001062"
     CDS             31523..31999
                     /locus_tag="VQO19_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET1349344.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            32027..32932
                     /locus_tag="VQO19_001063"
     CDS             32027..32932
                     /locus_tag="VQO19_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET1349345.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVVVAAPSTPSESGEIEDDEF"
     gene            32919..33734
                     /locus_tag="VQO19_001064"
     CDS             32919..33734
                     /locus_tag="VQO19_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET1349346.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            33741..34145
                     /locus_tag="VQO19_001065"
     CDS             33741..34145
                     /locus_tag="VQO19_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET1349347.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
BASE COUNT         9503 a         6642 c         8117 g         9911 t
ORIGIN      
        1 aacatatacc tacggcaagg cgacgttgac gtggtttgaa gagattttcg aagagtatta
       61 gaaaatgccg ataagggtct gcataccaag gctggtgagg atgatggcaa tccagcagac
      121 ggctccgaga acaatggatt ttccactgga tttgaccata gcgaccagat tagttttgag
      181 accgatggca ctcatggcca tgataatgag gaatttagag agttgtttga gaggggtaaa
      241 gaaactacta gacacaccga gagaggtcag aagggtggtt aggagcgatg caaggatgaa
      301 gtaaaggata aaaagtggga agactttttt cagttgtaag ccttgcttat ttttttgctc
      361 gcgactttgc cagtaggaga gaaagagagt gatggggatg atagctaggg tgcgcgtgag
      421 tttgacaatg gttgcggatt cgagggtatt ggtctggtag agactgtccc aagcgctagc
      481 tgtggcggtt acagaggaag tatcattgac cgcagttcct gcaaagaggg cgaagccgtc
      541 attggataga tgaagccagg tgccgagggt tggaaagatg agcgcagcca agacattgaa
      601 gaaaaagata acggagatgg cttgggctac ttccttttcc ttagcatgga taacaggcgc
      661 tgtcgctgca atggcagaac ccccacagat agaagaacct actccaatca aggtagccag
      721 ttttgtatcc agggcaaaga agcgctggaa gaggtaggca acaatcaagg ctattgaaat
      781 ggtggaaagg atgacaggga gtgaagattg cccaactgcg aagacttgag agatattgag
      841 accaaaacca agtaagataa cggcatactg gagcaatttc ttggaactaa aggtcaatcc
      901 aacatccagt tgtttataag acgagagaaa gggatgtagg agcattccca taaaaatcgc
      961 aaaaacgggt gcgccaataa cagggaagaa tcctcctaag taccaagata ggatggaaat
     1021 gagaaggcag accaagatgc ctgctccatt ttttgataga aatgacataa aaacctccaa
     1081 atagaatctg ttaccattat agacctgtaa agaggaaaag taaaatagaa agtggaaagc
     1141 tattctctaa tgtatttttg cggtcggggg gcttttgtag tataatagag atacgttttg
     1201 aaagtaggag gtatctatgg acttaactaa gcgctttaat aaacagttag ataaaattca
     1261 agtttcgttg attcgtcagt ttgaccaggc tatttcggag attcctgggg tcttgcgttt
     1321 gaccttgggg gaacctgatt ttacaacgcc agaccatgtc aaggaggcgg ccaagcgagc
     1381 gattgatcag aaccaatcct actatacagg gatgagtggt ctgctgactc tacgtcaggc
     1441 agctagtgac tttgttaagg aaaagtacca actggactat gctcctgaaa atgaaatctt
     1501 ggttacaatt ggggcgacag aggctttatc tgcgactttg acggctattt tggaagaggg
     1561 agacaaggta cttttgccag ctcctgctta tccaggctat gaaccgattg ttaacttagt
     1621 tggggcagaa attgttgaga ttgatacgac tgaaaatggt tttgtcttga ctcctgagat
     1681 gttggagaag gccattttgg agcagggtga taagctcaag gcggttattc tcaactatcc
     1741 agccaatccg acaggaatta cctacagtcg agagcagtta gaggccttgg cagctgtttt
     1801 acgcaagtac gaaatttttg ttgtctgtga tgaggtttac tcagaattga cctacacagg
     1861 cgaagcccat gtgtctctag gaacgatgtt gagagaccag gctattatta tcaatggttt
     1921 gtctaaatcg catgccatga caggttggcg tttggggctg attttcgctc ctgcggcctt
     1981 cacagcccag ttaatcaaga gtcaccaata cttggtcact gccgcaaata ccatggcgca
     2041 acatgctgcg gtagaagcct tgacggctgg taaaaatgat gcggagccca tgaagaagga
     2101 atatatccag cgtcgggact atatcatcga aaaaatgact gctcttggtt ttgagattat
     2161 caaaccagac ggtgccttct atatttttgc taaaattcca gcgggctaca atcaagactc
     2221 ctttgctttt ctgaaggatt ttgctcagaa gaaggccgtt gcctttatcc ctggtgcagc
     2281 ctttggacgt tacggggaag gctacgtccg cctatcttat gcagccagca tggagactat
     2341 caaagaagcc atgaaacgac ttgaggagta catgagagaa gcatgattca gtctatcacg
     2401 agtcaaggct tggtgcttta caatcgcaat tttcgtgagg atgacaagct cgtcaaaatt
     2461 tttacagagc aggttggcaa acgcatgttt tttgtcaaac acgctggtca gtctaagctg
     2521 gcgcctgtta ttcagccctt ggtgctggca cgatttctct tgcgaatcaa tgatgacgga
     2581 ctcagttaca tcgaagacta tcatgaggtc atgacttttc ccaagattaa tagtgacctc
     2641 tttgtcatgg cctatgcgac ctatgtggca gctcttgcag atgctagttt gcaggacaat
     2701 cagcaggatg ctcccttgtt tgcttttttg caaaagactt tggagttgat ggaagcaggc
     2761 ttggattatc aggttttgac caatattttt gaaattcaaa ttttgactcg atttggaatc
     2821 agcctcaatt ttaatgagtg tgtcttctgc catcgggttg gtcaggcttt tgacttttct
     2881 ttcaaatatg gagcctgcct ctgtccagag cattatcatg aggataagag acgttgtcat
     2941 ctcaatccca atatccccta tctgctcaat caatttcaag ctattgattt tgagactttg
     3001 gagaccattt cgctcaagcc tggaatcaag caagagctac gccaatttat ggatcaatta
     3061 tatgaagagt acgttgggat tcacctaaaa tcaaagaaat ttattgattc cctagcagac
     3121 tggggacaat tactaaaaga ggaaaagaaa tgaaaaaaat cgcagtagat gccatggggg
     3181 gcgattacgc acctcaggcc attgttgagg gggtcaatca agccctatct gacttttcag
     3241 atatcgaggt tcgactttac ggagatgaag ctaaaatcaa gcaatatctg acagcaacag
     3301 agcgcgtcag cattatccat acggatgaga agattgattc ggatgatgaa cctacgagag
     3361 ctattaggaa taagaaaaat gccagtatgg tattggcagc caaggctgtc aaagatggtg
     3421 aagcagacgc tgtcctttcg gctgggaata caggtgcctt gttggcagca ggattcttca
     3481 tcgtgggtcg tatcaagaat atcgaccgtc ctggactcat gtctaccttt cctaccgttg
     3541 atggaaaagg ttttgacatg ctagaccttg gtgccaatgc agaaaataca gcccagcacc
     3601 tccatcaata tgcggttcta ggttccttct atgctaaaaa tgtccgtggc attgcgcaac
     3661 cacgcgttgg tttgctcaac aacggaacag agagtagcaa gggcgacccg cttcgtaagg
     3721 aaacttatga attactggcg gctgatgaaa gtttgaactt tatcggaaac gtggaagcgc
     3781 gtgatttgat gaatggcgtt gcagatgttg ttgtggcaga tggtttcacg ggaaacgctg
     3841 tgctcaaatc catcgaaggg acagctatgg gaatcatggg cttgctcaag acagctatta
     3901 caggtggtgg tcttcgagcg aaactaggtg ccctccttct caaggacagc ctcagtggtt
     3961 tgaaaaaaca gctcaattat tcagatgttg gtggagcggt cttgtttggt gttaaggcac
     4021 ctgttgtcaa gactcatggc tcaagcgatg ccaaggctgt ttatagtacg attcgtcaga
     4081 tccgtaccat gctagaaaca gacgtggttg cccagactgc gcgtgaattt tcaggagaat
     4141 aaaagagatg acagaaaaag aaatttttga ccgtattgtg accattatcc aagagcgaca
     4201 gggagaggac tttgtcgtga cagaatcctt gagtctgaaa gacgatttgg atgcggattc
     4261 tgttgacttg atggagttta tcttgactct ggaagatgaa tttagtatcg aaatcagcga
     4321 tgaagaaatt gaccaactcc aaaacgtagg agatgtggtt aaaatcattc aaggaaaata
     4381 gcaatcggag ttccaagtca acggaagtag atggttttta gaaatgagaa atatcggaca
     4441 agctggtaaa atcttggctg acagtggtta tcaagggctc atgaagatat atcctcaagc
     4501 acaaactcca cgtaaatcca gcaaactcaa gccgctaaca gttgaagata aagcctgtaa
     4561 tcatgcgcta tctaaggaga gaagcaaggt tgagaatatc tttgccaaag taaaaacgtt
     4621 taaaatgttt tcaacaacct atcgaaatca tcgtaaacgc ttcggattac gaatgaattt
     4681 gattgctggt attatcaatc atgaactagg attctagttt tgcaggaagt ctaatagtaa
     4741 aaaagtgatt agaaaacatc ttttttaaaa atagagatga ttttgaaaca aaaaagctaa
     4801 ttcaagacgt ttcgatgcca attcaagatt tggatgaaaa aaattaatag atactgttat
     4861 actaaacttg tcaagtttgt aacaagacaa atattaaaaa taaaaaagag gtattcgtta
     4921 tgaatacaaa aaagatgtca caatttgaaa ttatggatac tgagatgctt gcttgcgttg
     4981 aaggtggcgg atgcaattgg ggagattttg ccaaagcagg tgttggagga ggagctatac
     5041 ttggaggtgt ggcctatgca gcgacatgtt ggtggtaatt atggatttta aaagttttat
     5101 tattggttta gtagttggta tatttggtcc ttatatggat gatttaatta gaaaaaaatt
     5161 tttaaagtct tcggagaaga aaacagaaaa atctgttaaa aaataatcaa aactataaat
     5221 gatgaatctg aatcaaaatt attttgcgca tgtaaagagg agtcttgcag taacgaatca
     5281 aaaaaaagga gtaactatga atcgtaattt agaatggtgt tatctattat gactataaat
     5341 agatcatacc agaggtggct tagaaatagc agggacatta gaaattgaag taactttaaa
     5401 taggatgtcg taaatgttgc tatcaatgat ttatttgtcc caagcttgcc tagggtgtca
     5461 gtaaaaaatc attttccttt cataccatat ttttagtagg tagaacgttt gttctgccta
     5521 tttttttatc caaaaagtgc agttgggagg gagataggct catttgggaa ggaagtccag
     5581 tttttgttta gtgattgggg taagatagtt gttatcagat gagtttatac tcttcgaaaa
     5641 tcaaattcaa accacgtcaa cgtcgccttg ccgtatatat gtgactgact tcgtcagtcc
     5701 tatctacaac ctcaaaacag tgttttgagc agcctgcggc tagtttccta gtttgctctt
     5761 tgattttcat tgagtattag ggaaaaggag atgaatatga aatttgggaa acgtcactat
     5821 cgtccgcaag tggatcagat ggactgcggt gtagcttcat tagccatggt ttttggctac
     5881 tatggtagtt attatttttt ggctcacttg cgagaattgg ctaagacgac catggatggg
     5941 acgacggctt tgggcttggt caaggtggca gaggagattg gctttgagac acgagctatc
     6001 aaggcggata tgacgctttt tgatttgccc gatttgactt ttccttttgt tgcccatgtg
     6061 cttaaggaag ggaaattgct ccactactat gtggtgactg ggcaggataa ggacagcatt
     6121 catattgccg atccagatcc tggggtgaaa ttgaccaaac tgccacgtga gcgttttgag
     6181 gaagaatgga caggagtgac tctgtttatg gcacctagtc cagactacaa gcctcataag
     6241 gatcaaaaga atggtctgct ctcttttatc cctatattag tgaagcagcg tggcttgatt
     6301 gccaatatcg ttttggcaac actcttggta accttgatta acattgtggg ttcttattat
     6361 ctgcagtcta tcattgatac ctatgtgcca gatcagatgc gttcgacgtt ggggattatt
     6421 tctattgggc tagtcatcgt ctacatcctc cagcaaatct tgtcttacgc tcaggagtat
     6481 ctcttgcttg ttttggggca acgcttgtcg attgacgtga ttttgtccta tatcaagcat
     6541 gtttttcacc tccctatgtc cttctttgcg acacgcagga caggggagat cgtgtctcgt
     6601 tttacagatg ctaacagtat catcgatgcg ctggcttcga ccatcctttc gattttccta
     6661 gatgtgtcaa cggttgtcat tatttccctt gttttatttt cacaaaatac caatctcttt
     6721 ttcatgactt tattggcgct tcctatctac acagtgatta tctttgcctt tatgaagcca
     6781 tttgaaaaga tgaatcggga caccatggaa gccaatgcgg ctctgtcttc ttctatcatt
     6841 gaggacatca atggtattga gactatcaag tccttgacca gtgaaagtca gcgttaccaa
     6901 aaaattgaca aggaatttgt ggattatctg aagaaatcct ttacctatag tcgagcagag
     6961 agtcagcaaa aggctctgaa aaaggttgcc catctcttgc ttaatgtcgg cattctctgg
     7021 atgggggctg ttctggtcat ggatggcaag atgagtttgg ggcagttgat tacctataat
     7081 accttgctgg tttactttac caatcctttg gaaaatatca tcaatctgca aaccaagctt
     7141 cagacagcgc aggttgccaa taaccgtcta aatgaagtgt atctagtagc ttctgagttt
     7201 gaggagaaga aaacagttga ggatttgagc ttgatgaagg gagagatgac tttcaagcag
     7261 gttcattaca agtatggcta tggtcgagac gtcttgtcgg atatcaattt aaccgttccc
     7321 caagggtcta aggtggcttt tgtggggatt tcagggtcag gtaagacgac tttggccaag
     7381 atgatggtta atttttacga cccaagtcaa ggggagatta gtctgggtgg tgtcaatctc
     7441 aatcagattg ataaaaaagc cctgcgccag tacatcaact atctgcctca acagccctat
     7501 gtctttaacg gaacgatttt ggagaatctt cttttgggag ccaaggaggg gacgacacag
     7561 gaagatatct tacgggcggt cgaattggca gagattcgag aggatatcga gcgcatgcca
     7621 ctgaattatc agacagaatt gacttcggat ggggcaggga tttcaggtgg tcaacgtcag
     7681 agaatcgctt tggcgcgtgc tctcttgaca gatgcgccgg tcttgatttt ggatgaggcg
     7741 actagcagtt tggatatttt gacagagaag cggattgtcg ataatctcat ggctttggac
     7801 aagaccttga ttttcattgc tcaccgcttg actattgctg agcggacaga gaaggtagtt
     7861 gtcttggatc agggcaagat tgtcgaagaa ggaaagcatg ctgatttgct tgcacagggt
     7921 ggcttttacg cccatttggt caatagctag aaagaggaga ggatgaaacc agaattttta
     7981 gaaagtgcgg agttttataa tcgtcgttac cataattttt ccagtagtgt gattgtaccc
     8041 atggcccttc tgctcgtgtt tttacttggc tttgcaactg ttgcagaaaa ggagatgagt
     8101 ttgtccacta gagctactgt cgaacctagt cgtatccttg caaatatcca gtcaactagc
     8161 aacaatcgta ttcttgtcaa tcatttggaa gaaaataagc tggttaagaa gggggatctt
     8221 ttggttcaat accaagaagg ggcagagggt gtccaagcgg agtcctatgc cagtcagttg
     8281 gacatgctaa aggatcaaaa aaagcaattg gagtatctgc aaaagagcct gcaagaaggg
     8341 gagaaccact ttccagagga ggataagttt ggctaccaag ccacctttcg cgactacatc
     8401 agtcaagcag gcagtcttag ggctagtaca tcgcaacaaa atgagaccat cgcgtcccag
     8461 aatgcagcag ctagccaaac ccaagccgaa atcggcaacc tcatcagtca aacagaggct
     8521 aaaattcgcg attaccagac agttaagtca gctattgaaa caggtgcttc cttggccggt
     8581 cagaatctag cctactctct ttaccagtcc tacaagtctc agggcgagga aaatccccaa
     8641 actaaggttc aggcagttgc acaggttgaa gcacagattt ctcagttaga atctagtctt
     8701 gctacttacc gtgtccagta tgcaggttca ggtacccagc aagcctatgc gtcagggtta
     8761 agcagtcaat tggaatccct taaatcccaa cacttggcaa aggttggtca ggaattgacc
     8821 cttctagccc agaaaatctt ggaggcagag tcaggtaaga aggtacaggg aaatctttta
     8881 gacaagggga aaattacggc aagtgaggat ggggtgcttc atcttaatcc tgagaccagt
     8941 gattctagca tggttgcaga aggtgcccta ctagcccaac tttatccatc tttggaaaga
     9001 gaagggaaag ccaaactcac agcctatcta agttcaaaag atgtagcaag aatcaaggtc
     9061 ggtgattctg ttcgctatac tacgactcat gatgccggga atcaactttt tctagattct
     9121 actattacaa gtattgatgc gacagctact aagactgaga aagggaattt ctttaaaatc
     9181 gaggcggaga ttaatctaac ttcggagcag gctgaaaaac ttaggtacgg ggtggaaggc
     9241 cgtctacaga tgattacggg caagaaaagt tatctacgtt attatttgga tcaatttttg
     9301 aacaaagagt aatgttcgtg tttttagagt taaataattt ttaaactgtg agaaagattc
     9361 ttcttgcagt tttttcttta caatttttga aaaacatctg ctatttattc ggttaaattc
     9421 ttgtgttttt tggttttttg tggtaaaatg tgctcaagta atacgaaagg cgaactttaa
     9481 aatgtcaaaa caattgatct attcgggaaa agctaaagat atctatacaa ctgaggatga
     9541 aaatcttatt atttcaactt acaaggacca ggcgactgct ttcaacggtg tcaagaagga
     9601 gcagattgca ggtaagggag tcttgaataa tcagatctca tcttttattt ttgagaaatt
     9661 aaatgcggct ggtgtggcga ctcactttgt ggagaaactt tcagacacgg aacaactcaa
     9721 taaaaaggtt aagattattc ctttggaagt cgtgctccgc aactatactg ctggttcctt
     9781 ttcaaaacgt tttggtgtgg atgagggaat cgccttggag actccgattg tcgaatttta
     9841 ctacaaaaat gatgatttgg atgatccatt tatcaatgat gagcatgtga aattcctaca
     9901 gattgcggat gaccagcaga ttgcctactt gaaggaagaa acgcgtcgta tcaatgaact
     9961 attgaaagtc tggtttgctg agattgggct taaattgatt gactttaagc tagagttcgg
    10021 ttttgacaag gatggcaaga ttatcttggc agacgaattt tcaccagata actgccgctt
    10081 gtgggatgct gatggcaacc acatggataa ggatgttttc cgtagaggat tgggagaact
    10141 aaccgacgtt tatgagattg tttgggaaaa gttgcaggaa ttgaaataat ctgtttgcaa
    10201 tggaaaacct tcgtctctca actaaaagga ctcaggctga aaaggtcccc cagacctttt
    10261 cactctgtag agaactaggt gaaccaaccg atgtttacga aattgtctgg gaaaagttgc
    10321 agggtttaaa ataacaacct caaggctgtt tgggaatatt gcaagagctg aaataaagga
    10381 ataagaattg atggataaac gtatttttgt tgaaaaaaag gctgattttc aggtcaagtc
    10441 agagagtttg gttagagagc tccagcacaa cttgggactg tcaagcttga aaagtattcg
    10501 tattgtgcaa gtatatgatg tatttgactt ggctgaggac ttgtttgcac ctgcagagaa
    10561 gcacattttc tctgagcagg taaccgacca tgttttagat gaagtatctg tgcaggcgga
    10621 tcttgctaac tatgctttct ttgccattga aagtctgcca gggcagtttg accagcgtgc
    10681 agcttcgtca caggaagcct tgcttttgtt gggaagttcg agtgacgtga cagtcaacac
    10741 agcccaactt tacttggtga ataaagatat tgatgcgact gagttggaag ctgtcaaaaa
    10801 ctacctgctc aatccagttg attctcgttt caaggatatc acgacaggga ttgccaagca
    10861 ggagttttca gagtcagaca agaccattcc aaaattgact ttctttgaaa gctatacagc
    10921 agaagacttt gctcgctaca aggccgaaca agggatggcc atggaagtgg atgatttgct
    10981 ctttatccaa gactacttta agtcaatcgg gcgcgtgcca actgagactg aacttaaggt
    11041 tttggacact tactggtctg accactgccg tcatacgact tttgagacag agttgaaaca
    11101 catcgacttt tcagcttcta aatttcaaaa gcaattgcag tcaacctatg acaagtatat
    11161 tgccatgcgc gaggaattag gtcggtctga aaaaccacaa accttgatgg atatggcgac
    11221 tattttcggt cgttatgagc gtgctaatgg acgattggat gatatggaag tctctgacga
    11281 aatcaatgcc tgctcagttg aaattgaagt ggacgttgat ggtgtcaagg aaccttggct
    11341 cctcatgttt aaaaacgaaa cccacaacca tccaacagaa attgagccat ttggtggagc
    11401 ggctacctgt attggtggag ctattcgtga tccgttgtca gaccgttcct atgtttacca
    11461 agccatgcgt atttcaggtg ctggtgatat tacagcaccg atttcggaaa ctcgcgctgg
    11521 gaaattgcca caacaagtca tttctaaaac agcagctcat ggttattctt catatggtaa
    11581 ccagattggg cttgcaacaa cctacgttcg tgaatacttc cacccaggct ttgtagctaa
    11641 acgtatggaa cttggtgccg ttgttggtgc ggctcccaag ggcaatgttg tccgtgaaaa
    11701 acctgaagca ggtgatgtga tcatccttct cggaggcaaa acaggtcgtg atggtgtcgg
    11761 tggtgcgacg ggctcttcta aggttcaaac agttgagtct gtagagactg ctggtgctga
    11821 ggttcaaaaa ggaaatgcca tcgaagaacg caagattcag cgcctcttcc gtaatggcaa
    11881 tgtcactcgt ctgatcaaga agtccaatga ctttggggca ggcggtgtct gtgtggctat
    11941 cggtgaattg gcagacggtc ttgaaatcga cctcaacaag gtgcctctta aataccaggg
    12001 cttgaatggt acagaaattg ccatctctga atcacaagaa cggatggcgg tcgtggttcg
    12061 tcctgaagat gtggatacct tcgttgccga atgtaacaaa gaaaatattg atgctgttgt
    12121 ggtggcgaca gtaactgaaa aaccaaatct tgtcatgcac tggaatggtg agacaatcgt
    12181 tgacttggag cgtcgtttcc ttgacaccaa tggtgtgcgc gtggttgtcg atgccaaagt
    12241 tgtggacaag gatgtcaaac tcccagaaga gcgtcaaaca tctgctgaaa cactggaatc
    12301 agataccctt acggttctat ctgacctcaa ccatgcaagt caaaaaggat tacagactat
    12361 ctttgactgc tctgttggac gctcaacggt taatcaccca cttggtggtc gttaccaact
    12421 cacaccaact gaggcatctg tgcagaaatt gccagttcaa cacggtgtga ctcatactgc
    12481 gtcggtcatt gctcaaggtt tcaacccata tgtagctgaa tggtctccat accacggtgc
    12541 tgcttatgcg gttatcgaag caactgctcg tttggtggct gctggtgcca actggtccaa
    12601 ggctcgtttc tcttaccaag agtatttcga gcggatggac aaacaagcag agcgtttcgg
    12661 tcagccagta gccgcccttc taggttctat tgaagcacaa attcagcttg gcttgccatc
    12721 tatcggtggt aaggactcca tgtctggtac ctttgaagaa ttgaccgttc cgccaacctt
    12781 ggctgccttt ggggtgacga cggcagatag ccgtaaggtg ctctctccag aatttaaagc
    12841 tgttggggaa aatatctact acatcccagg tcaagccctc tctgcagaga ttgattttga
    12901 cttgattaag aaaaatttta ctcagtttga agccatccaa gctgaccata aagtgacatc
    12961 tgcatcagct gtcaaatacg gtggtgtagt tgaaagtttg gctcttgcta cctttggaaa
    13021 ctatattggt gcagaggtga ccttgcctga acttaaaaca gctttgacag ctcaattagg
    13081 cggctttgtc ttcacatctc ctgaagaaat tgctggagta gagaaggttg gacaaacgaa
    13141 agcagacttt acactgactg tcaaccgtgt gaaactagat ggacacaagc ttgacagtgc
    13201 atttcaaggg acattggaag aagtttaccc aacagaattt acccgagcga aagaactaga
    13261 agaagtacca gctgtggcat cagatgttgt gattaaagcc aaagaaaagg ttgaaaaacc
    13321 tgtggtttac atcccagtct ttccaggaac caactcagaa tatgattcag ctaaggcctt
    13381 cgaaaaagaa ggtgcagagg tcaatttggt gccattcgtg accttgaatg aagaagctat
    13441 tgtcaagtca gttgaaacta tggttgacaa tatcgacaag actaatattc tcttctttgc
    13501 tggtggattc tcggctgcgg atgaaccaga tggttcagct aagtttatcg tcaatatcct
    13561 gcttaatgaa aaagtgcgtg tggctattga tagctttatc gcccgtggtg gtttgattat
    13621 cggtatttgt aatggattcc aagccttagt caaatcgggt ctcctaccct acggaaactt
    13681 tgaagctgct aacagtacta gcccaaccct cttctacaat gatgccaacc aacacgtggc
    13741 caagatggtg gaaactcgta ttgccaatac caactcacca tggttggctg gtgtgcaagt
    13801 gggcgatatc cacgctattc ctgtttcgca cggtgaaggg aagtttgtcg tgacggctga
    13861 ggaatttgca gagctccgtg acaatggaca aattttcagc caatacgttg actttaacgg
    13921 taaaccaagt atggattcta agtacaatcc gaatggttct gtccatgcca tcgaaggaat
    13981 taccagcaag aatggtcaaa tcatcggtaa gatgggccac tcagaacgtt atgaggatgg
    14041 tcttttccaa aatatcccag gcaataaaga ccaacacctg ttcgcatcag cggttaaaca
    14101 tttcactgga aaataagact tacagatttt ctaatagata gtatcagtaa tgtaaaagtc
    14161 atgtaaatct agctcttgat gattacaaat gaaaattagg tataaaaaat gacatacgaa
    14221 gtaaaatctc ttaatgaaga atgtggtgtt ttcggtattt ggggacatcc agatgctgct
    14281 aagttgacct attttggact ccacagtctt caacaccgtg gtcaggaggg ggcaggaatc
    14341 ctctccaatg atcaaggaca actgaagcgc catcgtgaca tggggctttt atcagaagtt
    14401 ttcagaaatc cagccaattt ggataaattg acaggagctg gtgcgattgg gcatgtgcgt
    14461 tatgcgactg ctggcgaagc ttctgttgat aacatccaac ccttcctctt ccgttttcac
    14521 gatatgcagt ttggtttggc tcataatgga aatctgacca atgcagcctc tctcaagaaa
    14581 gaactggaac aaagaggagc aattttcagc gcgacttcgg actctgaaat cttggctcac
    14641 ctcattcgtc gcagtcataa tcctagcctg atgggcaaaa tcaaggaagc gctcagtctt
    14701 gtcaaaggtg gttttgccta tatcttgctg tttgaggaca agttgattgc ggctcttgac
    14761 cctaatggct ttcgtccgct ttctatcggg aaaatggcca acggagcggt ggttgtttcc
    14821 tctgaaacct gtgcttttga ggtcattggt gccgagtgga tttgtgattt gaagccaggt
    14881 gagattgtga tcattgatga cgagggcatt cagtatgaca gctatacaga tgatacccag
    14941 ttggcgattt gttctatgga gtatatctac tttgcccgcc ctgattctaa tatccacggt
    15001 gtcaatgtcc atacggcacg taagagaatg ggagcgcaat tggcgcgaga atttaagcat
    15061 gaggcagata ttgtagttgg tgtgcccaat tcttccctaa gcgcggctat gggatttgcg
    15121 gaagaatcag gcttaccaaa tgaaatgggt ctgatcaaaa accaatacac ccagcgaact
    15181 tttatccaac cgactcaaga attgcgggag caaggagtgc ggatgaaact gtctgctgtt
    15241 tcgggtgttg tcaaaggcaa acgtgtggtc atggtggatg attccattgt acgtggaaca
    15301 acctctcgtc gtatcgttca gctcttgaaa gaagcgggtg cgactgaggt tcacgttgcc
    15361 attggaagtc ctgcactagc gtatccatgt ttctacggga ttgatatcca gacccgtcag
    15421 gagctgattg cagccaatca tacggtcgaa gaaactcgcc aaatcattgg tgcggacagt
    15481 ctgacttatc tttcaattga tggcttgatt gagtcgattg gtatcgaaac agatgcgccg
    15541 aacggtggtc tctgtgtcgc ttactttgac ggtgactacc caacgcctct ctatgactac
    15601 gaagaagact atcgtagaag tttggaagaa aagaccagtt tttacaagta ggcgacagat
    15661 tctccattaa agaaaaggaa aaaacaaatg acaaataaaa atgcatatgc ccagtcgggt
    15721 gtggatgttg aagcgggtta tgaagttgtt gaacggatta aaaagcacgt ggcccgtacg
    15781 gagcgtgcag gtgtcatggg agctcttggt ggctttggtg gtatgtttga cctttccaag
    15841 actggggtta aagaacccgt cttgatttca gggactgacg gtgtcggaac caagctcatg
    15901 ttggctatca agtacgacaa gcacgatacc atcgggcagg actgtgtggc catgtgtgtc
    15961 aacgacatca ttgctgcagg tgcggaaccc ctctattttc tcgactacgt agcgacaggg
    16021 aagaatgaac cagctaagct agaacaagtg gttgctggtg tggcagaagg ttgtgtgcag
    16081 gctggtgctg ccctcatcgg tggggaaacg gctgaaatgc cgggcatgta cggcgaagac
    16141 gactatgact tggctggttt tgcggtcggt gtggctgaaa aatctcaaat cattgacggt
    16201 tcaaaggtgg tagagggaga tgttcttctc ggacttgctt caagtgggat tcactcaaat
    16261 ggttactctt tggttcgtcg tgtctttgcg gattacacag gtgaggaagt cctaccagaa
    16321 ttggaaggca agaaacttaa ggaagttcta cttgagccga ctcgtatcta tgtcaaggct
    16381 gtcttgccgc tcatcaaaga agagttggtc aacggcattg cccacatcac aggtggtggc
    16441 tttatcgaaa atgtccctcg tatgtttgca gatgacctag ctgctgaaat tgatgaaagc
    16501 aaagttccag tgcttccaat tttcaaaacc cttgaaaaat acggtcagat taaacacgaa
    16561 gaaatgtttg aaatcttcaa tatgggtgtg ggactcatgt tggcggtcag ccctgaaaat
    16621 gtagagcgtg taaaagaatt gttggatgaa gcagtctatg aaattggtcg catcgtcaag
    16681 aaagaaaacg aaagtgtcat tatcaaatga aaaaaatagc ggtttttgcc tctggtaatg
    16741 gctcaaattt tcaggtgatt gccgaagaat ttccagtgga gtttgtcttt tcagaccatc
    16801 gtgatgccta tgtgcttgag cgtgcaaagc agctcggcgt tctgtcctat gcttttgaac
    16861 tcaaggagtt tgagagcaag gcagactacg aagcagccct tgtcgaactc ttggaagaac
    16921 accagattga cttggtttgc ctagcaggct acatgaaaat cgttggacca accttattgt
    16981 cggcttatga aggtcggatt gtcaacattc atccagccta cttgccagaa tttccaggag
    17041 ctcatgggat tgaggatgct tggaatgctg gcgtgggtca gtctggtgtg accattcact
    17101 gggtggattc gggtgtggat acaggccagg tcatcaaaca ggttcgtgtg ccacgactag
    17161 ctgatgatac cattgacaga tttgaagctc gcatccatga agcagagtac aggttgtatc
    17221 cggaagtagt gaaggctcta tttacagatt gactttttga tgattcatat gatatctttg
    17281 attttaaatt ggagtcagtg tttgttgaag acggcttcaa acggaggtat ttgtaatgtt
    17341 agaatctaaa aaaacaactc gatatgtatt ttatgtctat ctgatgttat taacttgggg
    17401 aatcttattt aagtttgaaa caaatcctga atttatagca tttttcttag ctccaaggta
    17461 tatcaattgg attccatttt cagaaccact aatagtcgat ggaaaaattg tttttgctga
    17521 aatgttattt aatctgattt tctttattcc attaggtgtt tgtttccctt tgataaaaac
    17581 taatttatct agtttaagaa tagtcgggac aggtttcttg attagtttat tgtttgagta
    17641 cttacagtat attttagcaa taggtataac agatataacg gatttgactt taaatacgct
    17701 aggtgtctgt gtaggcttac tgatttatca aatttttata agagtgttca aatcacagac
    17761 tagaaaatgg atcaatatct taggtatgct tagccttggt tttgcttatc ttgttttact
    17821 gttactgcat ttaattggtg tttaactaat gattaaaaag gagaatataa tgactaaacg
    17881 cgtcttaatc agcgtctcag acaaagcggg cattgttgaa tttgcccaag aactcaaaaa
    17941 acttggttgg gagattatct caacaggtgg aactaaggtt gcccttgata atgctggggt
    18001 ggataccatt gctatcgatg atgtaactgg tttcccagaa atgatggacg gtcgtgtgaa
    18061 gaccctccac ccaaatatcc acggagggct tctcgctcgt cgtgacttgg atagccactt
    18121 ggaagcggct aaggacaaca agattgagct cattgacctt gtggtggtca acctttaccc
    18181 atttaaggaa actatcctta aaccagatgt gacttatgct gatgcagttg aaaatatcga
    18241 tattggtggg ccgtctatgc ttcgttcagc agcgaaaaat catgccagtg ttacagttgt
    18301 ggtagatcct gctgactacg ctgtggtttt ggacgaattg gcagcaaacg gcgaaacctc
    18361 ttatgaaact cgccaacgtt tagcagccaa agtatttcgt cacacagcgg cttatgacgc
    18421 cttgattgca gaatacttca cagctcaagt gggtgaaagc aagcctgaaa aactcacttt
    18481 gacttatgac ctcaagcaac caatgcgtta cggtgagaat cctcaacaag acgcggactt
    18541 ttaccagaaa gctttgccta cagattactc tattgcttca gccaaacagc tcaacgggaa
    18601 agaattgtca tttaataata tccgtgatgc agatgctgct atccgtatca tccgtgactt
    18661 caaagatagt ccaaccgttg tggctctcaa acacatgaat ccatgtggaa ttggtcaagc
    18721 tgatgacatc gagactgctt gggactacgc ttatgagtct gacccagtat ctatctttgg
    18781 tgggattgtc gtcctcaacc gtgaggtgga tgctgcgaca gctgagaaga tgcacggcgt
    18841 tttcctcgaa atcatcattg caccaagcta tacggatgaa gcgctagcca ttttgatcaa
    18901 taaaaagaaa aacttgcgta tccttgcctt gccatttaat gctcaagagg ctagcgaagt
    18961 ggaagcagaa tacacaggtg tagtcggtgg acttctcgtg caaaatcaag acgtggtcaa
    19021 ggaaagccca gctgactggc aagtggtgac caaacgtcag ccaactgaga cagaagcgac
    19081 tgctcttgag ttcgcttgga aggctatcaa gtacgtcaaa tcaaatggta ttatcgtgac
    19141 caacgaccac atgacacttg gtgttggtcc aggtcaaacc aaccgtgtgg cttctgttcg
    19201 ccttgccatt gaccaagcca aagatcgtct gaacggggcg gtccttggtt cagatgcctt
    19261 cttcccattt gcggataacg tggaagaaat cgccaaagca ggaattaagg ccatcatcca
    19321 gcccggtggc tctgtccgtg accaagaatc catcgaagca gcggataaat acggcttgac
    19381 tatggtcttt acaggtgtga gacattttag acattaagaa gataaaaggg aagaaaacag
    19441 tttctttcct tttttggctt aaaatgctaa ctgaaacaag attaaaacga acttttttga
    19501 tataatgttg gtaaataatt cgcaaaagag gttgaggaat gaaactgctt gttgtcggtt
    19561 ctggtggtcg tgagcatgcg attgctaaaa agttacttga atcaaaagac gtggaaaaag
    19621 tctttgtagc tcctgggaat gacggtatga ctctggatgg tctggaattg gtaaatatat
    19681 ctatttccga acattataaa ttgattgact tcgcaaaggc caacgatatt gcttggacct
    19741 ttatcggtcc agatgacgcc cttgcggctg gtatcgtgga tgatttccat gcagctggtc
    19801 tcaaagcctt tggtccgaca agattggcag cggagctgga gtggtccaag gatttcgcca
    19861 aggaaatcat ggtcaaatat ggtgtttcga cagcagccta tggcacattt tcagatttcg
    19921 aggaagcaaa ggcctatatc gaaaagcatg gtgcgcctat cgtagtcaag gcggatggct
    19981 tggcgcttgg gaagggtgtc gtcgttgctg agacggttga gcaagcggtc gaagccgctc
    20041 atgagatgct tttggacaat aaatttggtg actcaggtgc gcgcgtggtt attgaggaat
    20101 tccttgaagg agaggaattt tcactctttg cctttgtcaa tggtgataag ttctacatca
    20161 tgccaacggc tcaggaccac aaacgtgcct acgatggcga caaagggcct aacacgggtg
    20221 gtatgggtgc ctatgcgcca gttccacact taccacagag tgtagttgat acagcggctg
    20281 acaccattgt caagccagtt ctagaaggga tgattaaaga aggtcgccct tatctgggag
    20341 ttctttacgc agggcttatc ctgacagctg atggaccgaa agtcattgag ttcaacgctc
    20401 ggttcggaga tccagaaact cagattatct tgcctcgctt gacctctgac tttgctcaaa
    20461 atatcacaga tatcctggat agcaaggagc caaatatcat gtggacggac aagggtgtga
    20521 ctctgggtgt ggttgtcgca tccaagggct acccgctaga ctatgaaagg ggcgttgagt
    20581 tgccagccaa gacagaaggc gatgtcatca cctactatgc aggggctaag tttgcggaaa
    20641 atagcagagc actgctctca aacggcggac gagtttatat gctcgttacc acagcagata
    20701 ccgtcaaaga agcccaagcc agcatctacc aagaactata ccaacaaaaa atagaaggac
    20761 tcttctaccg aacagatatc ggaagcaagg caattaagta aagatataag aataacgcgc
    20821 cgtagtcgcc aaacacgata atggtcgtcg tggtgaaaag accagaacag tgaatgttct
    20881 ggtcagggga aacttggaga ccttaggctc aaagtttagg aatgaaaccg aaggtttgct
    20941 tccgcctcca tcacctaaga ccattatcaa aaagaaaaat aaaaattcac aaaatacgtt
    21001 aatgatcgta tggtttgcga gcgttagcga gctaatatag aacaatcacc gccgttgtga
    21061 aagaacgatt ggatgataat ccaatcgttc agggaaattg gaagaccttg ggtttccaat
    21121 ttaggcatga gacacctttg gtggctgctg ccgtccctca caagctaagg tgattgttga
    21181 aaaagaggaa aaaggagaag aaatgaaacc agtaatttcc atcatcatgg gctcaaaatc
    21241 cgactgggca accatgcaaa aaacagcaga agttctagac cgcttcggtg tagcctacga
    21301 aaagaaagtt gtttccgcac accgtacacc agacctcatg ttcaaacatg cagaagaagc
    21361 atatagccgt ggtattaagg tcatcatcgc aggtgctgga ggcgcagccc acttgccagg
    21421 aatggtagct gccaaaacaa cccttcctgt cataggggta cctgtcaagt ctcgtgctct
    21481 tagtggagtg gattcactct attctatcgt tcagatgccg ggtggggtgc ctgttgcgac
    21541 catggctatc ggtgaagctg gagcgactaa cgcagctctc tttgccctcc gtctcctctc
    21601 tgtagaagat aagtccattg cggatgcact tgccaacttt gctgaagaac aaggaaaaat
    21661 cgcagaggag tcgtcaaatg agctcatcta aaacaatcgg aattatcggt ggcggtcaac
    21721 tgggtcagat gatggccatt tctgctatct acatgggcca caaggttatc gcgctggatc
    21781 ctgcggcgga ttgcccggtc tctcgtgtgg cggaaatcat tgtggcacct tataacgatg
    21841 tagacgccct ccgtcagttg gcagaccgtt gcgatgtcct cacttacgag tttgaaaatg
    21901 tcgacgctga cggtttggat gccgttatca aggatggaca actccctcaa gggacagacc
    21961 tgctccgcat ttcgcaaaat cgtatttttg aaaaggactt tttgtcaaac aaggctcaag
    22021 tcactgtggc accctacaag gtcgtgactt ctagcctaga cttggcagat atcgacttgt
    22081 cgaaaaacta tgtcctcaag actgcgactg gtggctacga tggtcatgga caaaaggtta
    22141 ttcgttcaga agtagacttg gaagcagcct atgcgctagc agaatcagca gactgcgtct
    22201 tggaagaatt tgtcaacttt gcccttgaga tttctgtcat cgtgtcagga aatggcaagg
    22261 aggtgacgtt tttcccagtt caggaaaata tccaccgcaa caatatcctg tctaagacca
    22321 tcgtaccagc ccgcatttct gaaagtctag tagacaaggc taaagctatg gcagtgcgaa
    22381 tcgcagaaca actcaacttg tctggaactc tctgtgtgga aatgtttgcg actgatgatg
    22441 acgttattgt caatgaaatc gccccacgac cacataactc tgggcactat tctattgaag
    22501 cctgtgattt ctctcagttt gacacccata ttctcggtgt tctcggagca ccattaccag
    22561 tcatcaaact ccatgcgcca gccgttatgc tcaatgtcct aggtcaacac gtcgaggctg
    22621 ctgaaaagta tgtcgcagaa aatccaagcg cccacctcca catgtatggt aaaatagaag
    22681 caaagcataa tcgtaagatg ggacatgtga ccttgtttag tgatgtaccg gatagtgtgg
    22741 atgagcttgg ggaagggatt gatttttagg acaagtctat gatacaaatt atcgttaata
    22801 catttattga aaaggataag actggagcag ttgttgaagt gttgtatgcc agtgctgacc
    22861 aagataaggt acaagctaaa tatgaagaac tagctgcaca ataccccgaa aattatttag
    22921 ctatctatga tgtaccgctg gatacggatt tgaatacact agatcattac ccgtctgtgt
    22981 ttattgaaaa agaggagttt gagtagaaat cttggtttac ctagatagct tattcccaac
    23041 agcttaagaa gaaaggaaaa attaacacat gatcaaccgt tactctcgcc ctgagatggc
    23101 gaatatttgg agtgaagaaa ataaataccg tgcttggctt gaggtggaaa tcctctctga
    23161 cgaggcatgg gctgagttgg gggaaatccc taaggaagat gtggctttga ttcgcaagaa
    23221 ggcggacttt gacatcgacc gtattttgga aattgagcag gagacgcgcc acgatgtggt
    23281 ggctttcacg cgtgcggttt ctgagactct tggtgaagag cgcaagtggg ttcactatgg
    23341 gttaacttct accgacgtgg tggatactgc ttatggttac ctctacaagc aggccaacga
    23401 catcatccgt cgtgaccttg aaaacttcac taatatcatc gctgacaagg ccaaggagca
    23461 caagttcacc atcatgatgg ggcgtactca tggtgtgcac gctgagccga caacctttgg
    23521 tcttaaattg gcaacttggt acagcgaaat gaaacgcaat atcgagcgtt tcgagcatgc
    23581 agctgctggt gtagaagctg gtaagatttc tggtgcggtt gggaactttg ccaatatccc
    23641 accatttgta gaggagtatg tctgcgataa acttggcatc cgtgcccaag aaatctctac
    23701 acaagtcctt cctcgtgacc ttcacgctga gtactttgcg gttcttgcca gcattgcgac
    23761 ttcaatcgaa cgtatggcga ctgagattcg tggtctacaa aaatctgagc aacgcgaagt
    23821 agaagagttc tttgctaaag ggcaaaaagg gtcttcagca atgcctcaca aacgcaaccc
    23881 aatcggttct gaaaatatga ctggtctggc gcgtgtcatt cgtggtcaca tgattacggc
    23941 ttatgaaaac gtcgctctct ggcacgaacg cgatatttct cactcatcag ctgagcgtat
    24001 catcacacca gatacgacca ttttgattga ctacatgctc aaccgttttg gaaatatcgt
    24061 caagaacttg acagtcttcc cagaaaatat gatccgaaac atgaactcga cttttggtct
    24121 tatctttagc caacgggcta tgttgacatt gattgaaaaa ggcatgaccc gtgagcaagc
    24181 ctatgacttg gtgcaaccaa aaacagccta ctcttgggac aaccaagtag actttaaacc
    24241 acttcttgag gcagattcag aagtaacatc acgtctcact caagaagaaa tcgatgaaat
    24301 cttcaaccca gtttattaca ccaaacgagt ggatgatatc tttgaacgtc ttggactagg
    24361 tgattaatta aaaaataaac agcgagcttc aatctcgctg tttatttttt atcgaaaaga
    24421 cttagtcttc ttttctttta gtgagtccat aggctgctag tgtggacatg agtcctgcga
    24481 ctactagtcc tgcagaatcg tgagttcctg tttcaggaag ttttttctct gttaccacag
    24541 gagctggatc ttgaggaaga gctttgcttt cctcagcagg agcagttgat ggagctggtt
    24601 ggcttgggat ttctagtttt ggtttttctt cagcaatagc ggcttgtccg ttttcatcgc
    24661 ctacatgtgt taccatagtt ccgacttcga ctatttgagt aacggcttcc tgtgctacga
    24721 cactatttac aagtgttttc acttccttac catcggcaga agtgctcaca gagtagaagt
    24781 tgctacgatg tccattgacg cccttagtaa tgacttgtgt ttttcctttg agtaagagtg
    24841 gattttcacg agtcactgtg gtaaatggaa tttcttcttc ttggatatcc agtctaggtt
    24901 ttacctcagt agttggtgca agaccacttt catcaccctt gtgagttaca ggagagccaa
    24961 cttcaaccac ttggtttata acttctttgg ttacctggct atcaaggact gtttctgttg
    25021 tttttccatt ttcagtgagt acagagatgt aatgagttcg ttcacctttg actcctgctg
    25081 tgataatatt ttcctgacca gctgggaggt taggattttc tttcttgata acttcaaatg
    25141 gaatttcttc agttcttgtg atgagttctg gtctggtttc aacattggca gccacttcat
    25201 tttcatctag gcttcctgaa tgagttgcag ctggtttgag gccttgaaga gcggctttta
    25261 ggttggctac aagtgtgtca agctcagctt gtttattacg gttgaggttg taatttagag
    25321 ctgttttagc tgcgtcaagg gcctcaagac tttctttact atatccttct aagtttgtag
    25381 gaattttagc taattcttcg cggagagcat tataattagc acggaagtag tctttgttgt
    25441 ggtctgcaaa ggcagtcatg agttcaaaga tttcctcttc cttgtactca gcgcttggtc
    25501 tatctgccca gattgaaagc atacttccga ctgttggaag atctacttca ggatatttgg
    25561 tagaagctag ttgattgaat ggaactttac cagaattttc aactgctttt gaaagagggt
    25621 aagcttcatc ttgtttgtga ttgcctataa cataatacca gtcaccgttg gtattcaaga
    25681 atttatagcc tttgcttgct aggtattgag gtgatgcgag gttatatccc caccagcctt
    25741 tagaccagta agaaatcaag acatctttgt caaactgaac atcgtccttg tcttcatagt
    25801 agaagccatc gttgaaggcc attggttgaa gccctctttc tttggccata gctgcgaggg
    25861 tgttggcata ttcggcaaat ttgccataga gttgatacca cttgaggtag taccagcctt
    25921 gggcactagt cgcatcgttg gcgtattcgt cagtaccaaa gttgaaaatc tttgttttac
    25981 ctgcaaagaa gtccatgtat ttaccgatga gggcttttac aaagttcatc gcttcttcgt
    26041 ttttcaagtc catagttgtt tttgaaactt tatcaaagtg ggcttgagga tttttaatac
    26101 ctaatttttc catggcaacc agcatagcat ccatgtgacc tggactgtta atagctggga
    26161 tgagaccaat gtccttagat ttagcgtatt caattagctc tgtcacttct gcctgtgtta
    26221 gtgcagtacc gtttggatcg tcgtagtaag ctttagttcc ttcgataata gcttttttaa
    26281 cgtcatcact agcataggtt tttccgttgg cagtaatggt catatcattg agtagaaagc
    26341 gaagtccgtc atttcctaga aggagatgga catcagaata tccgagctca ctggccttgt
    26401 ctacgatgcg tttgagctgg tccagagtaa agtatttgcg tccagcatcg attgagatta
    26461 ccttgttttt ggcaagtttt tcaacctcac gtttagcttc ttcttctttt tgagcttcag
    26521 gcgtgagggt caagttgttg acagtttctt gaagtttagc aatggcttga tcaatcgtat
    26581 cttgttgggc acggctaagg ttgctatcga gagagcgaat agctttttca gcttctttta
    26641 cggccgcgac gctttctgca gtataacggt tcaggtcttt tggtacctcg ttaagtgctt
    26701 gctctgcaga ttcataatca gctgcgaagt attcagcgtt ggcatttgca aaatgacgca
    26761 tgagtttgaa gaggtgtgat ggtgaataac gtgcagatgg agtgtcagcc caagcagcta
    26821 ccataccacc gatgattggg atatcagctc cttctgtttt tggtacagaa gtgattggtg
    26881 tgtttttaat accattgagc ccctgatcga gattgtacca gccttggcca tcagcgtttc
    26941 gtccaagaac gtagtaccaa gcatcattgg tattaaggat ttggtgacct ttttcagcta
    27001 gtagtttaga agaagcgaca tcgtagcctc cccaaccacc agtccacata gaaacgatga
    27061 tgtctttgtc aaaactacca aagcttgtgt cgctattgta gtagataccg tcgttaaagg
    27121 ccattggttt gagaccgtgc gattttacaa tacgagcgag gtcattggcg taggcaataa
    27181 atttttcata gccttttaca gggtagcctt cgtttggata gtatttatca gcttgaagca
    27241 cactccaacc tttagcatct gtcgcatcat tggcatattc atcaagtccg atgttgaaga
    27301 tttcagtctt tttcgcgaaa taagcagcat acttgtcgat aagggctttt gtaaaagcga
    27361 cagcttgttc gttgtcaaga tcgacagtac gggctgattt cttcccaaaa tagctaaagt
    27421 tagggttttg gattcccaat tctttcatgg cattgagaat cgcatccatg tgtccaggac
    27481 tatttactgt cggaatgaga ccgatacctt tatctttggc atagttaatc agatctgtca
    27541 tttgactttc tgttaagtga ttgccgtttg gatcgttgta ataatcattt gtaccttttt
    27601 caatggcgcg tttgacatcg tcactgtcat aggtcttgcc gttagctgtg atgctcatat
    27661 cgtccaacat gaaacggagt ccatcatttc cgactaatag gtgtaaatca gtgtagccat
    27721 aatgtttcgc tttatcgatg atttccttga gctgttctgg tgagaaatat ttacgtccag
    27781 catcaataga aacaattttc tttttcgcta gtttttcatt tacagttgca gcacgttcct
    27841 ttcctgcctc tgtttccggt ttgtcagcct ctgctttcgc ttcatctttt ttagctggtt
    27901 tatctttgtc agtcttgtcc gtatttgact ctttagaatc aacctctttc gcttcttcct
    27961 ttttagggct agcttcttct gcctttttat tagcagtttc tttttcagca gaagttggag
    28021 ttaccacttc tgctttatca ctaggagttg aactaacttc ctcttgtggt ttttcttctg
    28081 tttttggaag actagctacc ttatcagtag ctggagtttc tgtttctaca gtttttggag
    28141 cttctggttg aagctctgct ttaggtgttt tctcagtccg attttcggat gattgagggg
    28201 aatcagaaac cgtatggatg gtcggttggt tttctgtagt agtaggagta actccatcgg
    28261 ctgcaacagt ctgtgcttgg aaggcaaatc caattagaac agaagctgct cctacagcgt
    28321 atttacgaat agaaaaacgc tgttgttttt catgtttcat tgcaaaacct cctgattgca
    28381 ttgttatatt gatagcgatt atataaatca acgcccttat tttatttctt atattaacga
    28441 gagtcaagag gagatgacaa aaaactataa taagtataaa aaaatataaa atttaaactt
    28501 aagatttcag attggtcgga aaaaatgcat atatatatct aatataattt ttggttctat
    28561 ttctataaaa tattccacaa attatagaat cttccaaaaa taggtaagcg ctaccttttt
    28621 ggtgtggtat aataagcata gaaaaagccc gagcgattag gctcaggctt tcttcttagt
    28681 gatcacggtc acatgagatg aatttaatct tgtagtaatc agatcgtttg taagtttcac
    28741 tgtattctaa aacttggcca gttgattcga gtttggtgat tttagtttgt aggacagtag
    28801 ggaattgttc atcgactccg aggactgaag ccgcatgttc tggagttgga aagactattt
    28861 cgttgatttc ttcaaagtgt tcatcattca tgtgaatgtg gtagtctaac ttgaaacgat
    28921 tatagataga actatagtat tcaaggtttg gataatttgc gttgatatat tgttctggga
    28981 tgtaggatgt atggtagata taaacgacac cgtttgattc gcggatacgt tcaatcttgt
    29041 agtagaattg atcgccgcgt agacccaatt tttccaagta aacaagcttg tttccgcgtt
    29101 caattgaaag aacagttacc ttatcatctt tagcattgaa gagctcaata tctgaaaact
    29161 ctacaagctt gtgtttgcgt gcacgtgaaa cgaaggttcc ttttccttgt tggcggacaa
    29221 tatagccatc tttggcaagg tcgtttaagg cgcgaacaac tgtgatagag ctgacatcgt
    29281 acattgaaat gagttctgct tcagtgtaaa atttatctcc actgctaaac tgcccagaga
    29341 tgattttatt ttttaattcg tcttttatgt attgatattt gggaattgcc atatttttac
    29401 ctctattttc cttctccata gaaaatttta ccataaaagc gaaaaaaata gtagtctttt
    29461 gaataaaaaa ttagaataat agtttgaaaa attaagcgat atagggattg ctcatatttt
    29521 atcaatgtat tctatacaaa attattttag gtcctatatt ccgaatttaa agagcgtttg
    29581 aaatgggtct aaaaatgttt gaaactaatt taatgtgtgt ataatagtaa aaatgcagta
    29641 aatatcccga catttctatt gacaattcaa acagattggt ttataattaa tataacaaca
    29701 aatgaaagcg caaactttcg cggtcggaag gtagttttat gacacgattt gagatacgag
    29761 atgatttcta tctcgatgga aaatcattta agattttatc tggtgccatt cattatttta
    29821 gggttcctcc agaggattgg tatcattcgc tctataactt gaaggctctt ggttttaata
    29881 cggtagagac ttatgttgct tggaatttac acgagcctcg tgaaggtgag tttcattttg
    29941 acggtgatct ggatttagag aaatttctcc aaatagcgca ggatttgggt ctctacgcaa
    30001 ttgtgcgtcc gtctccattt atctgtgcgg aatgggaatt cggtggctta ccagcttggc
    30061 tcttgaccaa gaacatgcga attcgctcat ccgacccagc atatatcgag gcagttggtc
    30121 gctactatga tcagttattg ccaagactgg tgcctcgttt gttgaacaat ggtggcaata
    30181 ttctcatgat gcaggttgaa aatgagtatg gttcttacgg agaagataag gcttacctga
    30241 gagcgattcg acagctaatg gaagagtgtg gtgtaacctg tcccctcttt acatcagatg
    30301 gtccatggcg agctactctg aaagctggaa ccttaattga agaggacctc tttgtaacag
    30361 gaaactttgg ttctaaggca ccttacaact tttcgcagat gcaggaattc tttgatgaac
    30421 atggtaagaa atggccactc atgtgtatgg agttctggga tggttggttc aatcgctgga
    30481 aagaaccgat tatcacacgg gatcctaagg aattggcaga tgcagttcga gaggttttgg
    30541 aacaaggctc tatcaatctt tacatgttcc acggtggtac aaactttggt ttcatgaatg
    30601 gttgctcagc tcgaggaact ttggacctgc cacaagttac atcttatgat tacgatgccc
    30661 ttctggatga agaaggaaat ccaactgcta aatatcttgc agtcaagaag atgatggcaa
    30721 cacatttttc agagtatccg cagttggaac cactctacaa agagagtatg gagttggatg
    30781 ctattccact agttgaaaaa gtttctttgt ttgaaacctt agatagcttg tcaagtcctg
    30841 tagaaagtct ctatcctcaa aagatggagg agctgggaca aagttatggc tacctacttt
    30901 atcgaacaga aacaaactgg gatgcagaag aagaaagact tcgtatcatt gatggtcgag
    30961 atagggccca gctgtatgtc gatggtcagt gggttaaaac tcaatatcag acagagattg
    31021 gggaagatat tttttatcaa ggtaaaaaga aagggctatc taggttagat atcttgatag
    31081 aaaatatggg gcgtgtcaac tatgggcata agttcttagc ggatacgcaa cgtaagggaa
    31141 ttcggacagg ggtctgtaag gatctgcatt tcttactaaa ctggaaacac tatccactcc
    31201 cactagacaa tcctgagaaa attgattttt caaaaggatg gactcaagga caaccagcct
    31261 tttacgctta tgactttaca gtcgaagagc caaaagatac ttacctagac ttgtctgagt
    31321 ttggtaaggg agttgccttt gtcaatgggc agaatctagg acgtttttgg aacgttggcc
    31381 caactctctc actttatatc cctcatagct atctcaagga aggtgccaac cgtatcatta
    31441 tctttgaaac agaaggtcaa tataaagaag agattcattt aactcgtaaa cctacactaa
    31501 aacatataaa gggggaaaac ttatgacaat tgtaggatgc cgtattgatg gacgtttgat
    31561 ccacggacaa gtagccaatc tttgggctgg aaaactaaat gtttcacgca ttatggttgt
    31621 agacgacgaa gttgtcaaca acgatattga aaagagtggt ttgaaacttg cgacaccacc
    31681 aggtgtgaaa ttgagtattt tgccagttga gaaagctgca gccaatattc ttgctggtaa
    31741 atacgatagc caacgtctct ttatcgtggc tcgtaaacca gaccgcttcc ttggtttggt
    31801 agaagcaggt gtaccacttg aaacccttaa tgttgggaat atgtctcaaa caccagaaac
    31861 tcgttctatt acacgttcta tcaacgtagt agacaaggat gtggaagact tccacaaact
    31921 ggcagaaaaa ggtgttaaac ttactgctca gatggttcca aatgatccaa tttcagactt
    31981 tttgagctta ttaaaatagg aaaaaaattt ttaggaggtc attgttatga tacaatggtg
    32041 gcaaatttta cttctcactt tgtactcagc ttatcaaatc tgtgatgagt tgacgatcgt
    32101 ttcatctgca ggttctcctg tatttgctgg tttcattact ggtttaatca tgggagatgt
    32161 gactactggt ttacttatcg gtggtaactt gcaactgttc gttcttgggg ttggtacctt
    32221 cggtggtgct tctcgtatcg acgcaacttc tggtgcggtt cttgcgacag ccttctctgt
    32281 ttcacaagga attgatgcac cgcttgccat tactacaatc gctgtaccag tagcagctct
    32341 cttgacttac ttcgacgttc ttggtcgtat gactactacc ttcttcgctc accgtgtgga
    32401 tgctgcaatc gaacgctttg actataaagg tattgaacgc aactacttgc ttggtgcgat
    32461 tccgtgggct ctatctcgtg cccttccagt cttctttgcc cttgcttttg gtggtgcctt
    32521 tgtacaatca gtagtagact tcgttgaagc ctacaaatgg gttgcagatg gcttgacact
    32581 cgcaggacgt atgcttccag gtcttggatt tgcaatcttg cttcgttacc ttccagttaa
    32641 acgtaacctt cactaccttg ctatgggatt tggtttgaca gctatgttga ctgttcttta
    32701 ctcatatgta acaggtcttg gtggcgctgt tgctggtatc gtaggtactc ttcctgctga
    32761 agttgctgaa aaaattggtt tcgtgaacaa cttcaaaggt ttgtctatga ttggtatttc
    32821 tatcgtaggt attttccttg cagtgcttca cttcaaaaat agccaaaaag tagttgtagc
    32881 agcaccttct acaccatcag aaagtgggga aatcgaagat gacgaattct aattacaaac
    32941 ttacaaaaga agattttaat caaatcaaca aacgtagctt gtttactttc caattaggtt
    33001 ggaactacga acgtatgcaa gcttctggtt acctttacat gatcttgcct cagttgcgta
    33061 aaatgtatgg tgatggaact cctgaattga aagaaatgat gaaagttcat actcaattct
    33121 tcaatacttc gccattcttc cataccatta tcgctggttt tgaccttgcc atggaagaaa
    33181 aagatggtgt aggttcaaaa gacgccgtta acggtatcaa gacaggtttg atgggaccat
    33241 tcgctcctct tggggataca atctttggtt cacttgtacc tgctatcatg gggtcagtcg
    33301 cagcaactat ggctatcgct ggccaacctt gggggatctt cctttggatt gcagttgcag
    33361 tagcgtatga catcttccgt tggaaacagt tggaatttgc ttacaaagaa ggggttaacc
    33421 ttatcaacaa catgcaaagt accttgacag ctttgattga cgctgcatct gtacttggtg
    33481 tcttcatgat gggtgctctt gtagcaacag tgattaactt tgaaatttct tacaagttgc
    33541 caatcggtga aaagatgatt gatttccaag acatcttgaa ccaaatcttc ccacgtttgc
    33601 ttccagcaat ctttactgcc tttatcttct ggttgcttgg taagaaaggt atgaactcta
    33661 ctaaagctat cggtattatt atcgtacttg ctttggctct ttctgccctt ggtcactttg
    33721 cacttggaat gtaattcctt atgactaaat cattaatttt ggtgagccat ggtcgcttct
    33781 gtgaggagct tagaggtagc acagaaatga ttatgggccc acaagacaac atttacacag
    33841 tagctcttct tccagaagat ggcccagaag aatttactgc taaatttgaa gctgttattg
    33901 aaggattgga tgatttccta gtttttgcgg atcttctcgg tgggacacct tgtaatgtgg
    33961 tgagtcgctt gatcatggaa ggtcgtgata ttgaccttta cgcagggatg aatcttccaa
    34021 tggtgattga atttatcaat gcgagcctta caggcgcaga tgcggactac aagagccgtg
    34081 ctgcagaaag cattgtgaaa gttaatgacc tgttagcggg cttcgatgat gacgaagatg
    34141 aataatactc ttcgaaaatc tcttcaaact acg
//
LOCUS       DAVAGB010000020        33996 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVAGB010000020 DAVAGB010000000
VERSION     DAVAGB010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33996
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.020"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(1..238)
                     /locus_tag="VQO19_001066"
                     /pseudo
     CDS             complement(1..238)
                     /locus_tag="VQO19_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            494..1339
                     /locus_tag="VQO19_001067"
     CDS             494..1339
                     /locus_tag="VQO19_001067"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HET1349348.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(1486..2547)
                     /gene="dinB"
                     /locus_tag="VQO19_001068"
     CDS             complement(1486..2547)
                     /gene="dinB"
                     /locus_tag="VQO19_001068"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HET1349349.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSIAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            2942..5266
                     /gene="pflB"
                     /locus_tag="VQO19_001069"
     CDS             2942..5266
                     /gene="pflB"
                     /locus_tag="VQO19_001069"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HET1349350.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            complement(5634..5852)
                     /locus_tag="VQO19_001070"
     CDS             complement(5634..5852)
                     /locus_tag="VQO19_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349351.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(5948..6196)
                     /locus_tag="VQO19_001071"
     CDS             complement(5948..6196)
                     /locus_tag="VQO19_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349352.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVDGYVLEYHGLRATQDVD
                     AFYDQNQKINEIIARVGKQFNLNIHEELWLNNHVAKQI"
     gene            complement(6189..6473)
                     /locus_tag="VQO19_001072"
     CDS             complement(6189..6473)
                     /locus_tag="VQO19_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349353.1"
                     /translation="MVWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            complement(7085..7255)
                     /locus_tag="VQO19_001073"
     CDS             complement(7085..7255)
                     /locus_tag="VQO19_001073"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET1349354.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEKAG"
     gene            7816..8274
                     /locus_tag="VQO19_001074"
     CDS             7816..8274
                     /locus_tag="VQO19_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS alpha-glucoside transporter subunit IIB"
                     /protein_id="HET1349355.1"
                     /translation="MEVVLFSYCLNTRYLLQIVDIASSNDIILEEDTSEIMPGEIDVI
                     KSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIILA
                     PQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKSLQFVLEHYQAV"
     gene            complement(8400..9839)
                     /locus_tag="VQO19_001075"
     CDS             complement(8400..9839)
                     /locus_tag="VQO19_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET1349356.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(9843..11192)
                     /gene="trkA"
                     /locus_tag="VQO19_001076"
     CDS             complement(9843..11192)
                     /gene="trkA"
                     /locus_tag="VQO19_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HET1349357.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            11381..12229
                     /locus_tag="VQO19_001077"
     CDS             11381..12229
                     /locus_tag="VQO19_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HET1349358.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            12244..12792
                     /locus_tag="VQO19_001078"
     CDS             12244..12792
                     /locus_tag="VQO19_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HET1349359.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            12799..13047
                     /locus_tag="VQO19_001079"
     CDS             12799..13047
                     /locus_tag="VQO19_001079"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349360.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVR"
     gene            13158..14840
                     /locus_tag="VQO19_001080"
     CDS             13158..14840
                     /locus_tag="VQO19_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1349361.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELAKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            14825..15655
                     /locus_tag="VQO19_001081"
     CDS             14825..15655
                     /locus_tag="VQO19_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET1349362.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            15848..16351
                     /locus_tag="VQO19_001082"
     CDS             15848..16351
                     /locus_tag="VQO19_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HET1349363.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      16405..16639
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            16804..17367
                     /locus_tag="VQO19_001083"
     CDS             16804..17367
                     /locus_tag="VQO19_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET1349364.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     gene            17381..18007
                     /locus_tag="VQO19_001084"
     CDS             17381..18007
                     /locus_tag="VQO19_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET1349365.1"
                     /translation="MKGSFALLLFVILGYMVKFYPETLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPDILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            18035..18424
                     /locus_tag="VQO19_001085"
     CDS             18035..18424
                     /locus_tag="VQO19_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HET1349366.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQTLLADRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            18429..18878
                     /locus_tag="VQO19_001086"
     CDS             18429..18878
                     /locus_tag="VQO19_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HET1349367.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGMSFILELV"
     gene            19006..19593
                     /locus_tag="VQO19_001087"
     CDS             19006..19593
                     /locus_tag="VQO19_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HET1349368.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            19983..21590
                     /locus_tag="VQO19_001088"
     CDS             19983..21590
                     /locus_tag="VQO19_001088"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HET1349369.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(22149..23780)
                     /locus_tag="VQO19_001089"
     CDS             complement(22149..23780)
                     /locus_tag="VQO19_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HET1349370.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            24073..29052
                     /locus_tag="VQO19_001090"
     CDS             24073..29052
                     /locus_tag="VQO19_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HET1349371.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGTVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLHYQGHEVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNKVLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            29142..30338
                     /locus_tag="VQO19_001091"
     CDS             29142..30338
                     /locus_tag="VQO19_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HET1349372.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            30474..31001
                     /locus_tag="VQO19_001092"
     CDS             30474..31001
                     /locus_tag="VQO19_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET1349373.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFCFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            31078..31434
                     /gene="glnR"
                     /locus_tag="VQO19_001093"
     CDS             31078..31434
                     /gene="glnR"
                     /locus_tag="VQO19_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HET1349374.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            31471..32817
                     /gene="glnA"
                     /locus_tag="VQO19_001094"
     CDS             31471..32817
                     /gene="glnA"
                     /locus_tag="VQO19_001094"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HET1349375.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(32907..33026)
                     /locus_tag="VQO19_001095"
     CDS             complement(32907..33026)
                     /locus_tag="VQO19_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HET1349376.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            33514..33996
                     /locus_tag="VQO19_001096"
                     /pseudo
     CDS             33514..33996
                     /locus_tag="VQO19_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT        10374 a         6252 c         7281 g        10089 t
ORIGIN      
        1 gccagtattt ttagttctac ttgccgatta tcgtgttgaa attgttcacg attggggtca
       61 gaaagaagtt taagagcgat gagacagtct tggttgagct gtcgaaaaga cagatctaag
      121 agttcaaaac cagctttatt atttgaaaaa gtgagtggtt taagaacagt tttcctcgaa
      181 cattcaaggc tgtaacatcg tgtttatttt tagcgacatc aatgcccaca taaagcatgg
      241 gagtacctcc agatatagta tttcaagtct acttggttat ccacgaactt tttgccttgt
      301 taccttagac gagataaaac gtctatgcgt tatcaaactc attaccaatt gaaacaaaaa
      361 gctgtggtta gaccctttcg gaaatcgtca agcgattgga ggaaatgaac taatccacag
      421 tggcttattc caagtatacc acttgggctt tggcagtagc taactgcgtt aaatataata
      481 taaggagaaa tatatgtatc ttattgaaat tttaaaatct atcttcttcg ggattgttga
      541 aggaattacg gaatggttgc cgatttccag tacaggtcac ttgattttag cagaggagtt
      601 tatccaatac caaaatcaaa atgaagcctt tatgtccatg tttaatgtcg tgattcagct
      661 tggtgctatt ttagcagtta tggtgattta ttttaacaag ctcaatcctt ttaaaccgac
      721 taaggacaaa caggaagttc gtaagacttg gagactatgg ttgaaggtct tgattgccac
      781 tttgccttta cttggtgtct ttaaatttga tgattggttt gatacccact tccataacat
      841 ggtttcagtt gctctcatgt tgattatcta cggggttgcc ttcatctatt tggaaaagcg
      901 caataaagcg cgtgctatcg agccaagtgt aacagagttg gacaagcttc cttatacgac
      961 cgctttctat atcggactct tccaagttct tgctctttta ccagggacta gccgttcagg
     1021 tgcaacgatt gtcggtggtt tgttaaatgg aaccagtcgt tcagttgtga cagaatttac
     1081 cttctatctt gggattcccg ttatgtttgg agctagtgcc ttaaagattt tcaaatttgt
     1141 gaaagccgga gaactcttga gctttgggca attgtttttg ctcttggtcg cgatgggagt
     1201 agcttttgcg gtcagcatgg tggctattcg cttcttgacc agctatgtga aaaaacacga
     1261 cttcaccctt tttggtaaat accgtatcgt gcttggtagt gttttgctac tttacagttt
     1321 tgtccgttta tttgtataag aaaaaccttg aaggggcaac tcttcaaggt tttatactct
     1381 tagaaaatct cttcaaaccg cgtcagcttt atctgcaacc tcaaaacagt gttttgagca
     1441 gcctgcggct agcctcctag tttgctcttt gattttcatt gagctttaaa atccagtcat
     1501 ggtaatcccc aataggcgga cacctctttc tttctcgctt aattcttcat agagttgcag
     1561 ggctatttgg cttatctgac tagcatcttg tgttttttga gcaatacttt ttcgtttggt
     1621 aagagttgaa aagtcctcgt agcggatttt caaaatgaca atttttccag ctttttcttg
     1681 ttgatgtaga ttgagagcga ctttttctga tagaagagtc agctcttttt tgatatcttc
     1741 ctcagcacgg agaatcttcc cgtaggtttt ctccttgccg attgatttac ggatgcgatt
     1801 ggatttgact ggagagttgt gaatgccacg agcctttcga tacagatcat agcctagtct
     1861 accaaaacgg tctattaggg tcacctcagg aacttcaagt aaatcagcac cagtaaaaac
     1921 gcccatttga tgaagacgtt ctactgtctt ttttcctact ccatgaaatt tggaaatatc
     1981 catttgtttg agaaaatcct cagcctgttc aggtagaatc actgtcaaac catgaggttt
     2041 ttgataatca ctcgccattt tagctaagaa cttgttatag gaaataccgg cagaagcagt
     2101 tagatggagt tcttgccaga tatctttttg aatgaggcga gcaattttga ccgctgactt
     2161 gataccgagt ttattttctg tcacatccaa ataggcttcg tcaatactca tgggttcaat
     2221 caaatctgta tagcgcttaa aaatagctcg aatctggagt cccacagctt tgtatttctc
     2281 ataatttcct gagataaaga cggcctgggg acaacgttca taagcttcct tggaactcat
     2341 ggcagaatgg acaccaaaag ctcgagcctc atagctacag gtagaaacga ctccccgccc
     2401 acctgtttgt cgagggtcgc ttccaataat gacaggtttt cctctgagtt taggattatc
     2461 cttgatttcc accgcagcaa aaaaggcatc catgtcaata tggatgattt ttcttgacaa
     2521 atcatttaac aaaggaaaaa tcaacatgcc tagcaccttt ttatactttt caaaaatctc
     2581 ttcaaaccac gtcagcttcc atctgcaacc tcaaaacagt attttgagct gacttcgtca
     2641 gttctattta caacctcaaa gcagtgcttt gagcagcctg cggctagctt cctagtttgc
     2701 ttttcgattt ccattgagtg ttactgctta ttttctttta ttataccctt ttttctgaaa
     2761 aaaagaaaaa aggactttat ttttttcaaa aatataatac agtttgaaat aaaatataga
     2821 ctgttttaga aaagaaagtg taaaaatagg gattttgcac ttgttgaaat cggttacttt
     2881 atggtatact tgtcttatga atgtaacaga tgactgttac tagaaaaaag aggacattaa
     2941 tatggttgtt aagacagttg ttgaagcaca agatattttt gacaaagctt gggaaggctt
     3001 caaaggcgta gattggaaag aaaaagcaag tgtatcacgc tttgtacaag ctaactacac
     3061 accttatgat ggagacgaaa gcttccttgc aggaccaaca gagcgttcac ttcacatcaa
     3121 gaaaattgta gaagaaacta aagcacacta cgaagaaact cgtttcccaa tggacactcg
     3181 tccaacatct atcgctgata tccctgctgg atttatcgac aaagaaaatg aagttatctt
     3241 tggtatccaa aatgatgaac tcttcaaatt gaacttcatg ccaaaaggtg gtatccgtat
     3301 ggctgaaact actttaaaag aaaatggata cgaaccagac ccagctgttc acgaaatctt
     3361 cactaaatat gtaacaacag ttaacgacgg tattttccgt gcctacactt caaatattcg
     3421 tcgcgctcgt cacgcacaca ctgtaactgg tcttccagat gcatactcac gcggacgtat
     3481 catcggtgtt tacgcacgtc ttgctcttta cggtgcagac tacttgatgc aagaaaaagt
     3541 aaacgactgg aatgcaatca aagaaatcga tgaagaaaca atccgtcttc gtgaagaagt
     3601 aaaccttcaa taccaagcat tgcaacaagt tgttcgcctg ggtgaccttt acggggttga
     3661 tgttcgcaaa ccagcgatga acgtgaaaga agcaatccaa tgggttaaca ttgctttcat
     3721 ggctgtctgc cgtgtgatta acggtgctgc tacatctcta ggtcgtgtac caatcgtatt
     3781 ggacatcttt gcagaacgtg accttgctcg tggtacattt actgaatcag aaatccaaga
     3841 attcgttgat gatttcgtta tgaaacttcg tacagttaaa tttgctcgta caaaagctta
     3901 tgaccaattg tactcaggtg acccaacctt tatcacaact tctatggctg gtatgggtaa
     3961 cgacggtcgt caccgtgtta ctaagatgga ctaccgtttc ttgaacactc ttgacaacat
     4021 cggtaactca ccagaaccaa acttgacagt tctttggact gacaaattgc catacaactt
     4081 ccgtcgctac tgtatgcaca tgagccacaa acactcttct atccaatacg aaggtgtaac
     4141 aacaatggct aaagacggat atggtgaaat gagctgtatc tcatgctgtg tgtctccact
     4201 tgatccagaa aatgaagaac aacgccacaa catccagtac ttcggtgctc gtgtaaacgt
     4261 tcttaaagcc cttcttactg gtttgaatgg tggttacgac gatgttcaca aagactacaa
     4321 agtatttgat atcgaaccaa tccgtgacga agttcttgaa ttcgaatcag ttaaagcgaa
     4381 ctttgaaaaa tctcttgact ggttgactga cacttacgta gatgccttga acatcatcca
     4441 ctacatgact gataggtaca actacgaagc tgttcaaatg gccttcttgc caactaaaca
     4501 acgtgccaac atgggattcg gtatctgtgg atttgctaac actgttgata cattgtcagc
     4561 tatcaaatac gctacagtta aaccaatccg tgacgaagat ggctacatct acgattacga
     4621 aacaatcggt gactacccac gctggggtga agatgaccca cgttcaaacg aattggcaga
     4681 atggttgatc gaagcctaca caactcgtct acgtagccac aaactataca aagacgcaga
     4741 agctacagta tcacttttga caatcacatc taacgttgct tactctaaac aaactggtaa
     4801 ctcaccagtt cacaaaggtg tatacctcaa cgaagatggt tctgtgaact tgtctaaact
     4861 tgaattcttc tcaccaggtg ctaacccatc taacaaagct aaaggtggtt ggttgcaaaa
     4921 cttgaactca ctttctagcc ttgactttag ttatgcagct gacggtatct cattgactac
     4981 acaagtatca cctcgcgctc ttggtaagac tcgtgatgaa caagttgata acttggtaac
     5041 aatccttgat ggttacttcg aaaacggtgg acaacacgtt aacttgaacg ttatggactt
     5101 gaacgatgtt tacgaaaaga tcatgtcagg cgaagacgtt atcgtacgta tctctggata
     5161 ctgtgtaaac actaaatacc tcactccaga acaaaaaact gaattgacac aacgtgtctt
     5221 ccacgaagtt ctttcaatgg atgacgcctt ggatgcattg agctaatcaa gttcttgaat
     5281 aatgaaaagg aaccctcggt caaacgactg agggttttgt gcttgggata gtgtgagcaa
     5341 ttccttcggc gcaatatgca atgtttttgg gaaggaatag tggaccgaat ctgaaatata
     5401 atagattgaa actagaatag tacaccttta tttctaaaac attcttagaa atcgatttga
     5461 ctgtcctgat cgatttgtcc tattcttatt tcattttact atagtccact gaaacgtctc
     5521 aaacagcgct agaaattgac tggaattctc taagcgattt gttcagattt tatttcattt
     5581 catcataaaa aacaagacga ctggctaatt gacaatcatc ttgtttgata ctgttaataa
     5641 aattcgcgaa gtttatcttg attttcttta aaaaattttt ctaaccaatc cataccataa
     5701 gcataactaa aaccttctaa tagaacagag aggtcaatag tatcaaatcc catgtctttt
     5761 aaatatttaa aggtatcgaa tggtgaatga aagtttttgt atttaataat tgcaccaata
     5821 tcttgcaaat cctgctctct gatactcatc atcttcattc ctaacacata ctcaataggg
     5881 actactaaaa cggtcagatt ctcaaatgag tacaaggatt cgcataaact taagggaggt
     5941 tgtttgttca tatttgcttt gcaacatgat tgttgagcca taactcttcg tggatgttaa
     6001 gattaaactg ttttcctaca cgagcaataa tttcattgat tttctgattt tggtcataaa
     6061 aagcatcaac atcttgtgtg gcacgtaaac catgatattc taagacataa ccatcgacac
     6121 agataattgt taaagtcaga ttttcctgaa ttaattcctt atttagggct tggaagaccg
     6181 gtttcatttt atccatgttt gtatttctcc atcaattttt gaacattggt taacttagca
     6241 ggtttattta atgaaatcac atatttatga gttggagtat gctcttgaaa ggcatacttc
     6301 aagctaattt tttgaaaacg ggttagttct ttggagtcta gcaacttttc tacatcttgg
     6361 tttgttaaat aagaatagtc ttcaaaaata acttttcgca aatagcgaaa ccaatggctt
     6421 gcgttgaatt gtgattgttt ggatgcctgt atcatataat cgtaccaaac cattgtcttc
     6481 ctcctataaa atttagttta tattattgta gtttatattc aaaaatgtag tttttcttaa
     6541 ttagctcgta tctataggat gatactgaaa atcttcttgt tgctttaaat cacaatcgaa
     6601 aaattctgtt tttcatctta gaaaagaatg tttagaaatg taaaatgaac cttttttctt
     6661 atccgaaaac cttactaaag tatataattt aggaagtcaa ttctgtatga taatgtttgt
     6721 actatcgtcg agtttttgct tgattgccta acgagataaa ttttagaaga attttcggtg
     6781 tgatttgaca agcttctgac tggaaggata gttacactag tattgtttat taaaatgagc
     6841 agatagagaa aatttggaat ctatttgctt attatcaatc gtttttttag cttatttgtc
     6901 ttagattggt atagaactga tctatggatt aatcctcttg tatcttatcc tgttcctaaa
     6961 tatgttggta gaaaaatgaa gcagttgtta cgagtgtctg tattgggaaa aattttgtct
     7021 atacaattct ttaaatgata tgaaggctag gaatgccaaa acactgacat atttcgttta
     7081 aagcctatcc agccttttca attgtatttg tagaaatgct atcagtaata tattcgcgaa
     7141 cactatgatt tacaacagtg tggtcgtaca tctttgtaac tttattatac aacaaccatt
     7201 tacaggtgta aagttgagca gtgtctttag taaatttagg gacttgtttt gtcatagttt
     7261 tgatacctgt attcgttgtt tcatgagtat ttgacgtttc ttttcatgta ggcatttcaa
     7321 caattagaat gatatttttc cgaggatgaa cttatatatt gtgacttttt agagttatga
     7381 tgcctcttga tttgactatc gctatcaatt tcatccactt ttacagtttc atggttttat
     7441 gaaccgaaac atctaggtac aggttttagc atcaattgat tgtttttgag ccatatgaag
     7501 ttgaaacgtg gagatgcttt tcttgtgata acgccctatt caaagaggca taaccgtttt
     7561 tggagagagt tcagtactat gtggcgctaa atactatatg taaaacatat attaaacaag
     7621 atttaactaa ggagaattgt aaaaacaaaa atgagaattt catataaagt ttattctagg
     7681 agtatgtatc ttgaataaaa attgttattt aagttctggg ggttatgatg aatgttttta
     7741 taataataaa atgcagctag aagaaaagtt attttaatat aaatcactca acatagcgag
     7801 aaggcggttt cctatatgga agtcgtcttg ttttcatatt gtctaaatac gagatattta
     7861 ctacagattg tagatattgc aagctcaaat gatattattt tagaggagga tacaagtgaa
     7921 ataatgcctg gtgagataga tgtaataaaa agtaaggagt tgaaagtact ggttctttgt
     7981 gcagggtctg gaacaagtgc gcaattagcc aatgcaatta acgagggcgc tcaattagca
     8041 gaagttagag tgattgcgaa ttcaggagcg tacggagctc attatgatat tatgggtgtt
     8101 tatgatttaa ttattctggc tccacaagtt cggagttatt atagagagat gaaggtggat
     8161 gcagaaagat taggtattca gatagttgct accagaggaa tggaatatat tcatttaaca
     8221 aagagtccaa gtaaatcctt acaatttgta ttggagcatt accaagctgt gtagtaagtt
     8281 tttccatctt ttatttgagt aaggattttg cttacagata ggcttggatt taaaaacgtt
     8341 cccccttttt taatataaga atccctcttt cacaattgta aaaagaggga ttttgtattt
     8401 tatctcttag accaagttct cttcataaag agaaggagga ttgggtaaat ctccaagcgc
     8461 cctgcaatca ttgcaaagga taggagaatt tttgagatgg gactaaagat tgagaaacta
     8521 gaagtggttc ctagaatagg cccgatatta ttgaaacagc taaagacagc gctggtcacg
     8581 accagaaaat cattgctatc taggctgaca ataaagataa gcgctagcaa aatcatagca
     8641 tagatgacaa agtacttgag aatcttatgc tgggtatctt tatcaatcac cgtttgattc
     8701 acatggaggg tcaaaacacg gtggggcgat aggattgaca aaatttggtt tttggcaatt
     8761 tttgaaagga tgaggcctcg aataatcttg agtccacctg cagttgatcc agcagagcca
     8821 ccgattgcca tgaggaaaag gaggataaac tgggagaaga ggggccagtt ggtaatatct
     8881 ccatatccaa aaccagttgt tgtaatgatg ttggaaacct ggaagaaggt catttcaaag
     8941 ctctttgaaa accctgggta gaggtagagg gtgttgaggc taatcaagcc tgtagaaacc
     9001 agtacaatga ccaagtaagc ccgaagttct tcgtcaccaa agaaggcctt gatgcgacgg
     9061 agcatgaggt agtagtagag gttgaaattt accccaaaaa ccagaactcc gatactgacc
     9121 agataggtaa tcagtgagct gccatagtgg gcaattccgt cgttatagac ggtaaagcct
     9181 ccagttcccg ctgtccccat agcaatgaca aaactatcgt agagaggcat accagctaga
     9241 taatagatga tgacaaagag ggagaagaga gctagataaa ggagatagag aatctgggca
     9301 gtgtttttta gtttggatac aaccttgcca aaaacaggac ctggaacctc agccttcatc
     9361 acctctaggt ggctattttt ggcattgtcc ataatagcaa gtgcaaaaac aagcactccc
     9421 atccctccaa tcaagtgggt aaaacttcgc cagaagagga gggaacggct gagaaccgaa
     9481 atgtcgttca aaatacttgc tccagtagtt gtaaacccag aactaatttc aaaaaaggca
     9541 tcaataacgc tagggatttg cccagaaaag acaaagggga gaccaccaaa gaaagaccaa
     9601 aggatccaac agagggcaac gatcaagact ccctccttgg cataaatccg ttgatttttt
     9661 ggcttctgta aactccctga accgcctaac aatacgagaa tccctatggt cgaaaagagg
     9721 gctgtaaaga cttggctcga ttcacggtaa tagacagcga tagccacagg aaccaagagg
     9781 agaacagctt caatcaaaag taactttgaa aggaggtaac gaatcatact tttattcatt
     9841 tcttacctcg caatcaagtc ataaatcttg gtgatgtttg gcaacaaggt tgttactagg
     9901 agcttgtctc caacttccaa catatcctcc ccagttggga aaatagtctt gccctttcga
     9961 ataatggctg caataagaac cccttttttc aatttcagtt gagaaagagg tttggcagtc
    10021 attttattgg cttccttgat atggaattgc agggtttcaa tttggccatt ggctagatgg
    10081 tgcatggctt gaaggtctga atactgggca ttaactcgac cacgaataaa gtgcataatc
    10141 gtatctacag cgatgctttt aggtgtgatg atacttgaaa aatcaggcgc attgataatc
    10201 tcgaggagac tggtacgatt gaccttagta atatttttct gtacacctac cctgtcaagg
    10261 aacatagatg taatcagatt ttcctcatcg acacctgtta gagtcgcaac ggcatcatag
    10321 tgttgagcac tttcttccag caggatatct tttgcggttc catctccttg aacgatgtag
    10381 agatttggga atttctcgct aaagaagctg gcgatttcag gattgatttc aatgactttt
    10441 gtatcgatac gactatcttt gagaatacca agtagataat aggcaattct acctgcccca
    10501 acgatgagaa ggctcttcac ggcgcgtgat ttaaaataat tatggaagag tatcatatcg
    10561 acacggttac cagtgacaaa gattctatct ttatcctgta cagtcatgtc accgcttgga
    10621 atgataattt gatgatccct ctctatcgca cagacaatga cattaccaaa ttttttacga
    10681 aaatcagaaa tgggcatttg gcaaagaccg ctggtggact tgacgacaaa ttccatgagg
    10741 ctaacgcgtc caccagcaaa gcgttcgaca gacagggcgt tggggaagtc aatgatattc
    10801 gcgatagcgc gggcagccaa gagctcagga ttaacgataa gagaaaaacc gagaatattc
    10861 ttttccttga aataagagtt agaatattca gggttccgca cccgaacgat agtttcttta
    10921 gctcccattt tcttggctag aactgctgca atcatgttga cttcatcgtg ctcagtcagg
    10981 gcgataaaga tatcacaatc ttggacgctg gcttgctcaa gaatggcaaa atcggcccca
    11041 ttaccaagga taccaatgat atcaaagcga ctgacaatat gattgagaac agcttcgtct
    11101 tgctcaatca gcaaaacatc atgcttttct gcaaccaagg agcgacagag ggcaaaacca
    11161 acttttcccc ctccgacaag gataattttc ataataaaac ctactttttc atgatgtaac
    11221 tatcataccc tttttcaaga aaaaatgcac ctactagcta ataacaagaa cttttagtag
    11281 gaaatttgct ataaggtaaa actataccct aaccaattga aatagctatt agcgactttc
    11341 tctgaaatat ggtatgataa aggatataca aggagataaa atgaataata atttactggt
    11401 attacaatca gactttggtc tggttgatgg tgcggtatcg gctatgattg gagtggcttt
    11461 agaagagtct ccaaccttaa aaatccatca cttgacgcac gatatcacgc cttataatat
    11521 ttttgagggg agctatcgtc tctttcagac ggtggattac tggcctgagg gaacgacgtt
    11581 tgtatcggtt gtcgatccag gtgtcggttc gaaacgtaag agtgtagttg ccaagactgc
    11641 aaaaaatcaa tacattgtca cgccagataa tgggacgctt tcctttatca agaaacacgt
    11701 tggcattgta gccattcgtg agatttctga ggtggccaat aggcgtcaaa acacagagca
    11761 ttcttatacc ttccacggtc gtgatgtcta tgcctatact ggtgctaaac tggccagtgg
    11821 tcacattact tttgaggaag tagggccaga gctcagtgtg gaacagattg tagagcttcc
    11881 agtcgtagcg accatcatag aagatcatct ggtgaaggga gccattgata ttctggatgt
    11941 gcgtttcggt tcgctttgga cctctatcac acgggaagaa ttttacaagc tggaaccaga
    12001 atttggtgat cgttttgaag tgaccatcta tcatgctgat atgctggtct atcaaaatca
    12061 ggttgtctat ggcaaatcat ttgcagatgt gagaattggg caacccatcc tttacatcaa
    12121 ctctctctat cgtttaggtt tggctatcaa ccaaggttcc tttgccaagg cctataatgt
    12181 aggtgtcggt tcatcttgga ccattgaaat aaagaaaata gaaggataaa ataggagaat
    12241 agtatggaaa tcaaatttac aattaaacaa gttgttgctg tcggaattgg cgctgccctc
    12301 tttgtcgtca tcgggatgat caacattcca acccctgttc caaatacaag catccagctt
    12361 cagtatgcgg tacaagcgct actttctatt atttttggac cgattatcgg tttgcttgtc
    12421 gggttgattg gtcatgcaat caaggactct cttgctggtt atggtctatg gtggacttgg
    12481 attatcgcta gcggactctt tggtctagtt gtgggacttt ttagaaagta cgttcgagtg
    12541 atcaatggtg tttttgactg gaaagatatt cttattttta acctcattca actacttgca
    12601 aatgcccttg tttggggtgt cttggcacca cttggagatg ttgtgattta tcaagaagcg
    12661 gcagaaaaag tatttgcaca agggattgtt gcgggaattg ccaatggtgt atctgtagct
    12721 attgcaggaa ctcttctctt acttgcctat gcaggaaccc aaactcgtgc aggaagtttg
    12781 aaaaaggact aatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaggttgc
    12841 tcaaaacagt gttttgagat tgtggataga actgacgaag tcagctcaaa acatggtttt
    12901 gaggttgtag atgaaactga cgaagtcagt aaccatacct acggcaaggc gaagctgacg
    12961 tggtttgaag agattttcga agagtataaa atgatgggga aggctgggca actagtcttt
    13021 ttcgatgttt atagattagt taggtaagta agctaggata ggaatctttt tggcgctaag
    13081 attttaagag gagagactgc aagaagggct tgatttatga taaaatagaa gtctaagaag
    13141 cgaatgaaga gagtaagatg aaagaagcta taattgagtg gaaggatttc tctttccggt
    13201 atgaaacaca acaagaaccg accttgcaag ggatagactt gaccatttac aagggagaga
    13261 aagtcttaat tgttggacca tctgggtcag gtaaatctac cttgggtcag tgtttgaatg
    13321 ggattattcc caatatttac aagggtcaga catatggaga atttttgata aagggtcaag
    13381 tagcctttga tatgagcatc tatgataagt ctcatctggt tagcacagtt ttgcaggata
    13441 cagatgggca gtttattggc ttgtctgtgg cagaagattt ggcgtttgct ctggaaaatg
    13501 atgtgacagc cctagatgag atgaaaggtc gtgtttataa atgggctgaa aagctggacc
    13561 ttcttccttt actggatcag cgtcctcagg atttgtcagg tggacaaaag cagcgagtca
    13621 gtctggctgg tgtcttgatt gatgaaagtc cgattctctt gtttgatgag ccactcgcca
    13681 atctagatcc caagtcaggt caggatatta tcgaattgat tgaccagatt cataaggaag
    13741 aggggacgac gactctgatt atcgagcacc gtttggagga tgttctgcat cgccctgtgg
    13801 atcggattgt cttgataaac gatggtcgta tcctttttaa tgggagccct gaccagttgc
    13861 ttgcgactga tttattgact caaaatggaa ttcgagaacc cctttatcta acgactctcc
    13921 gtcaattagg tgtggactta gtcaaggaag aacagttagc gaatctggat aacatgtcta
    13981 tctcaaaagg tcaggttcag ctgcagaatg aactggcaaa agaaactcca gaattgcagt
    14041 cactctttaa attagaggac gtgtctttct cttatgatga tagaccgatt ttaaaatccc
    14101 tacatttaga tattaaaaag ggtgaaaaga ttgctattgt cggaaaaaat ggagcaggga
    14161 aatcaactct agccaaggct ataagtagct ttattcagac ggaaggacgc tatctttggg
    14221 aaaaacagga tataaaaggc gattctgttg cagagcgggc ggaacgagta ggctatgtgc
    14281 tacaaaatcc taatcaaatg atttcaacca atatgatttt tgatgaggtg gctctagggc
    14341 tccgtttgcg aggtgtggat gagaaggaaa ttgaaacgag agtctatgaa accttgaaaa
    14401 tctgtggact ttatgaattc cgtaattggc ctatttctgc cctgtcattt ggtcagaaaa
    14461 aacgtgtcac cattgcttca attttggtct taggagctga aattattctc ctagatgaac
    14521 cgactgcagg tcaagatcag aagaactata ctgagattat ggaatttctc gaagagttac
    14581 atcaaaaagg gcataccatt gtcatgatta cccatgatat gcaattgatg ctggattatt
    14641 cagaccgggt ccttgtcatg gtggatggag aattgattgc cgatactgtt ccagccagtc
    14701 tgttgagcga tcctgagctg ttagtaaaag ccaatctaaa agaaacctcc atctttaact
    14761 tggctaagaa actagatgtg gatccactgg atttaacggc attttacaaa gaaaggagag
    14821 agggatgcaa gctaaattaa tcggttacca gcatagagat actgtgattc atcgcttgtc
    14881 aggagctggg aaacttctct ttttcattct ggtatcattg gcggccatga ttagctatga
    14941 taccagaatg ctcttgctga ttgccatctt ttcagtcttt ctcctctatt tatcagaaat
    15001 tcgctttaaa gatgtttcct ttgtagccgt ttttgcgacg gtatttgccg ttttaaacgt
    15061 tttgatggtc tatctctttt ctcccgagta tggggttgga ctttatggag agagaagtgt
    15121 gatttggcag ggaatcggtg tctacactct aaccagccag gagctctttt atctgctaaa
    15181 tttggccatt aagtatcttt gcaccattcc tctggctatt atctttttga tgacaaccca
    15241 tcctagtcag tttgcttcca gtttaaatca aattggtgtg ccctataaga ttgcttattc
    15301 tgtcagcctg accttgcgct atattccaga tttgcaggaa gaattcttta ctatcaagat
    15361 gtctcaggag gcgcgtggga tggaattatc caagaaagct tctcttatgc aacgaatcaa
    15421 aggcaatctg ctcattatta cgcccttgat ttttagctcg ctagaacgca ttgataccat
    15481 tgcgactgcc atggagcttc gccgctttgg gaaagagaaa aaacgcacat ggtatagtta
    15541 tcaggccttg aaaaaaggag actatattac cttgctcttg gcaaccttgt ttttagtagt
    15601 tagtttacta cttatcttgc agaatcaggg acgattttac aacccttgga aatagcttga
    15661 aaaaattgaa aaaatcaagt catttctatt gacaatgatt ctgaaagtgt tatactaaga
    15721 aagtagtttc gctgatttac ttcaaacctg ttgtgaggta agttaacgat gccttaacca
    15781 cgctgtttgc tgagcttgac tccgggcagt gtggctattt ttttgcaatg gtgaaaggaa
    15841 gcaagtcatg acaaatcaca ttgtattatt tgaacctcaa attccacaaa atacaggcaa
    15901 tatcgcgcgt acttgcgctg cgaccaattc tcccctccac atcatcaagc ctatgggctt
    15961 tcctattgat gaccgcaaga tgaagcgggc tggattggat tactgggata agctagagat
    16021 ttatttttac gagagtttag aagatttcat atctcagatg aagggaaaac tctatctgat
    16081 ttcgaaattc gcggaaaaaa tctattctga ggtggattta tcgactgacg aggaccatta
    16141 ttttctcttt ggacgtgaag acaagggctt acctgaagat tttatgcgag aacatcctga
    16201 gaaggctctc cgtattccca tgaatgatga acatgtccgc agtctcaatg tgtctaatac
    16261 cgtctgcatg attgtctatg aggctcttcg ccagcagaac tttgcaggtc ttgagctcgt
    16321 ccatacctat gaagtggata aattgaaata aaaaatgaaa atgaacaaaa tgcttgcgct
    16381 tgcaagcgtt ttttgttatg ataaaagagt cttcagggca gggtgtgatt cccgaccggc
    16441 ggtgacttta actaggaaat gatcttttcc ttttatactt tgttgacaag ctttgcctaa
    16501 ccagaagtta tgcctacagc ttgtcgccta gtctaaaaga aaaatctcta tttctttctc
    16561 tttaaagaag tccgcgagcg caagctgatg tggtgagatt ccacaaccga cagtatagtc
    16621 tggatgggag aagacgaaag aatagctttg tctgttttga tagatttata gccggattgt
    16681 aaccacttgc tttgtttttc tttaatagag taagagggaa cttttgggat ataaaaagtg
    16741 agaatagata gaggaatcct ttccaacttc ttctgatttt atagaaaatt ggaggaacct
    16801 gttatgacaa acacacgtcg actttcgacc attgcaattc tatcagccat ctcatttgtg
    16861 ctgatgtact ttgattttcc gcttttacca gcggcatctt tcctcaagat cgaatttagt
    16921 atcttgccag tccttgtggg tctggtggtc atggatttgc ctgctgctct aggagtgctc
    16981 ttgcttcgct cactcttgaa gttgcttctt aacagccaag gagtgaatac ttacattggt
    17041 ttgccgatga atatcgtagc tttgggagtt tttgtcatcg tatttgcttt gatttggaaa
    17101 aaggaacgga caacccttcg tttcctacta ggctctctag ctggaactat tggtttaacc
    17161 ttggccatgt tggttctcaa ctatgtttat gctgttcctt tgtacgctaa gtttgctaac
    17221 tttgatattg gaaaaatttt gggactttcc aactacctaa tgaccatggt attacctttt
    17281 aacttgattg aaggtgttat cttttccgtt tcattctggt tgttgtatgt tctcttgaaa
    17341 ccaaccttaa aacattatga gagataaaca aacattttta atgaagggca gttttgccct
    17401 tttacttttc gttattcttg gctacatggt caaattttac cctgaaacgc tggtcaattt
    17461 tgaccaatcg attcagactg ccattcgagg agacttacca gattatttga ctattctttt
    17521 tcgagccctc acacgtctga ttgatatccc agtgattatc acttgggttg tcattacagc
    17581 ttttgtcttt tatcgtaagc gatggaagat agaaagtttc ttcatgctgg gaaatctggc
    17641 tttggcaggt cttttaatcg tgacctttaa aaatatctac cagcgcccac ggccagatat
    17701 cttacatctg gtggaggaga agggattttc cttcccaagt gggcattctc tggctgtaac
    17761 cttgatggta ggtactttga ttgttattct tagtcagcgg attaaagatc cagtctggag
    17821 aaaaatcgta caaatcgtcc ttggcctcta cctagtcagt gtgctggtat caagagtcta
    17881 tctgggagtt cattacccat cagacgtcct tgccagtctc tgtgtgggct tgggagtcct
    17941 gtttatcgag tttcccttct atgacaagct ccgcttccaa tggcgattta aaggcaaaca
    18001 gaagtgagta tcgaattccc ttgaggagaa agaaatgaaa gtcaacatag cagatcttca
    18061 tccgactcaa ctatatttat cagaaaagaa gttgcaagat attcagatgc tttaccagtc
    18121 ggcagaaaca atccaagtcg atccaatcag tattcttgcc tttggagatt gtttgctgat
    18181 tacagatggg catcacaggg cttatcagac tttattggca gatcgggata cgatttctgc
    18241 tgagtgggat agagatggtg gtgatgaact atatcatctc tatgcgcaag cttgcgagga
    18301 aagaaagatt tactctgttt ttgatttaga agatcgtatc ctagctcaag atgggtatga
    18361 agcaaaatgg tataactggt gtgatggttt taatcaagca gcaactcttt tgttgaaaag
    18421 gtagtgcatt gtgttttgtt ccttattata aggtcaatca ttgtgaggaa gcttttgctt
    18481 ggtatcagga tgtgaacttg gtttacctcg tagatggggt gaagcttcct tacagtcaag
    18541 cgaccttgga agccatgtat tcctatttgg atcggcatgg tgagcttttt tggattgaag
    18601 tcaaggagaa gggagaatgg tttccaattg gggatattac actatctcag gataatctcc
    18661 ccattgtgat tgggaattcc gcttaccaac atcgaggact tggaaaaaag attctaagtg
    18721 ctttgattga attggctcga gtaaaaggat ggaaagaatt gagagtcaag gaaatctaca
    18781 cctacaatca tgcttctagg aggtgtttca agtcgcttgg atttgtggaa aatggagcaa
    18841 cagaaaaagg aatgagtttt atattggaat tagtctaatc ctgccatttt ctccccctta
    18901 acctttgact attctgcaaa attatcgtaa aataaagagt aaatgataaa atgaggtcag
    18961 agtctgttcg ctctggcgat agtagtataa atgaggagaa acgctttgga attagaagta
    19021 tttgctgggc aagaaaaaag tgaactatct atgattgagg tagcgcgtgc tatcttggaa
    19081 cttcgtggtc gcgatcatga gatgcatttt agcgatcttg taaacgaaat tcaaaactac
    19141 cttggaacat caaacagcga tatccgcgaa gctttgcctt tgttctacac agagttgaac
    19201 tttgacggta gcttcatctc acttggggac aacaaatggg gtcttcgttc atggtatggt
    19261 gtggacgaaa tcgacgaaga aatcatcgct cttgaagaaa atgacgacga tgaagtagca
    19321 ccaaaagcta agaaaaaacg tgtcaatgcc tttatggatg gtgattcaga tgccattgac
    19381 tacaatgcag atgatccaga agacgaagat gcatacgaag cagatccagc tctttcatac
    19441 gatgatgaaa atccagatga tgaaaaaaat gaagtggaag cttatgatgc agaaatcaac
    19501 gaaatcgctc cagatgactt gggagaagat gtggatctca acgaagacga cgacgagttt
    19561 tcagatgacg acgctgaaac cagcgaggaa taagagttag ctattgacaa ttatcctatt
    19621 tttaggtatc atattgtttg ggcacctctt ttagaggtcg gggctcccta gttcttaggg
    19681 agctattttt gttttttcaa gaagttatct tcttgtattt tatactcaat gaaaatcaaa
    19741 gagcaagcta ggaaactagc cgtaggctgc tcaaaacact attttgaggt tgtagataag
    19801 actgacaaag tcaggaacac atatctacgg caaggcgacg ttgacgcggt ttgaagagat
    19861 tttcgaagag tattagctgt gaatctggtg cagtcgtccc agattattct tattagtagg
    19921 gtcttgtttt ctatatcccc tcgtagttaa caagaccttg agcattttag aaagaggaat
    19981 ctatgtctac gaaatatatt tttgtaactg gtggtgtggt atcgtctatt gggaaaggga
    20041 ttgtggcagc gagtctaggc cgtctcttga aaaatcgtgg tctcaaagta accattcaaa
    20101 agtttgaccc ttatatcaat attgatccgg gaaccatgag tccttaccag cacggggaag
    20161 tttttgtgac agatgacgga gctgagacag atttggactt gggtcactat gaacgtttca
    20221 tcgatatcaa tctcaacaaa tattccaacg tgacaactgg gaaaatttac agtgaagttc
    20281 ttcgtaaaga acgccgtgga gaataccttg gggcaactgt tcaagtcatt cctcatatca
    20341 cagatgcttt gaaagaaaaa atcaagcgtg ccgctctaac gaccgactct gatgtcatta
    20401 tcacagaggt tggtggaaca gtaggagata tcgagtcctt gccattccta gaggctcttc
    20461 gtcagatgaa ggcagatgtg ggtgcggata atgtcatgta tatccataca accttgcttc
    20521 cttacctcaa ggctgctggt gaaatgaaaa ccaaaccaac ccaacactct gtcaaagaat
    20581 tgcgtggctt gggaatccaa ccaaatatgt tggttattcg tacagaagag ccagctggtc
    20641 aaggaattaa aaataaactg gcccagttct gtgatgtggc accagaagcc gttatcgaat
    20701 cgttggatgt tgaacacctt taccaaattc cactgaactt gcaggcacaa gggatggacc
    20761 aaattgtttg tgatcatttg aaattagacg caccagcagc ggatatgaca gaatggtcag
    20821 ccatggtgga caaggtcatg aacctcaaga aacaagttaa gatttccctt gttggtaagt
    20881 atgtggagtt gcaagatgcc tatatctcag tggtcgaagc cttgaaacac tctggctatg
    20941 tcaatgatgt agaagttaaa atcaattggg tcaatgccaa tgatgtgaca gcagagaatg
    21001 tagcagaact cttgtctgat gcggacggga tcatcgtacc aggtggtttt ggtcaacgtg
    21061 gtacagaagg gaaaatccaa gccatccgct atgcgcgtga aaatgatgtt ccaatgttgg
    21121 gagtctgctt gggaatgcag ttgacatgta tcgagtttgc tcgtcacgtt ttaggtcttg
    21181 aaggtgccaa ttctgcagag cttgcaccag aaacaaaata ccctatcatt gatatcatgc
    21241 gtgatcagat tgatattgag gatatgggtg gaacccttcg tttgggactt tatccgtcta
    21301 agttgaaacg tggctctaag gctgctgctg cttatcacaa tcaagaagtg gtgcaacgcc
    21361 gtcaccgtca ccgttatgag tttaataatg ccttccgtga gcagtttgag gcagcaggtt
    21421 ttgtcttttc aggagtttct ccagacaatc gtttggtaga aatcgtggaa attcctgaaa
    21481 ataaattctt tgtagcttgt cagtatcatc ctgaactgtc aagccgtcca aaccgaccag
    21541 aagaactcta cactgccttt gttactgcag cggttgagaa cagcaattag caaaatcaga
    21601 acctttgaga aaaatctcag aggttttttg catacgatga tattgcagta tatctgaggt
    21661 aggagtcctc tgtatgtacc tgctaccgtt gaaatcaata gcgactccct cttgccctgt
    21721 gctagtgaat ggatttatca gtatattgaa atgaaataaa atttgaacaa attaattcgg
    21781 aaagccaaat caatttctag caaagtttta ggaactggat tgtatagtga attgaaataa
    21841 gatgtgaaca tctctatcag gaaagtcaaa ttaatttata gaaatatttt agcagtcaag
    21901 atggactgtt atagattcaa tatactatac ttttttaatt taatccacta taataaaatg
    21961 aaataataac aggacaaatc gttcaggaca gtcaaatcga tttctaacaa tgttttagaa
    22021 atagaggtgt actattctag tttcaatata ttatatatct gcagaatact ctttcagttt
    22081 cattcagcct agtcttgctt aggaaaaagt aagaagccat ccaattatga tggatagctt
    22141 cttggttatt agatttgttc tgcaaaaacc ttttcagcaa ggttcatagc gtggtctgat
    22201 acacgagtgt agtgtgagat gatgtcgata aagttgaccc cagcttgtgt tgaacattcg
    22261 cctttgttga ggcgtttgat gtgggttttt ctgagaacac gttctatctt attgattgct
    22321 tcatgacgtt ctacaagact gcgtgctttt tcaatatcat tgttttccac actatccaga
    22381 gcatctttga taaagtcact agtttggcgg taaacttcct ctaattcttt caaggcggca
    22441 tcagaaaatt caacattttt ccgttgaaga tagtcagtca gattgagtag agcctccgtg
    22501 tggtctccaa tccgttccaa atcacgggag gaatcaagga tattggtaag cacttcactt
    22561 tctttttggc tgagagcttc gcttgaaagg gcaatgagat aacgtgttaa ttgctcatcg
    22621 atggtgttaa ttgcttcttc ggttttatgc cctttttcag caactttttc atccaagtca
    22681 atgatgtact tataggaaag gtcaaaggct ttagcagcgt agtttcctaa gtgcaagagc
    22741 tctttcttag catttcctag agcgatagat ggggcctgtt tgatgaaatg ttcatcaaga
    22801 tataagggtt cgtatttgac aacctcgtcc tctccaggaa taatcttggt tacaaagtaa
    22861 gccagagctc cgataaatgg aaattggaca atggtgttgg taatattaaa ggttccgtga
    22921 gcaaaggcga tggtcatttc cggtgctaga tttagcgtag cttcaaacca atgaatcagg
    22981 acagtaaaag gaactagaaa aataacgcag acaactgttc cgataacgtt gaaggcaaca
    23041 tgagctcctg ctacccgttt agctgcaata ttagccccta aagaggcaat gatggctgta
    23101 atggttgtcc cgatattgtc accaaataga actggcaaag ctccctgtag atcaattaga
    23161 ttgccggcgt agaggttttg taaaatccca atggtagccg aagaagcttg aattagcaag
    23221 gtcaagccag taccgacaaa gacacccaaa acaggattct tacttagctc aatcatatag
    23281 tccttaaaga cctgtaaatc cttgagtgga gccattgcgc cgctcatgag attgagggca
    23341 aaaaagatac caccgacacc aaagaggatg cgtccgatat tattgactgt ccgatttttc
    23401 gtaaaaaaaa gacagacggc accgataaag agcataggta gggcatagtt acctaattta
    23461 aaaccgatga gaaaggatgt gacagttgtc ccaatattag cacccatgac aatcccgata
    23521 gcctgacgta aggttaagag accggcactg accaggccga ctgtgataac tgttacacca
    23581 gaactagact gaattagagc agtcatccca ataccaacca gaactccaaa gaaaggatta
    23641 ctagtatatt tgtcaatgta aaaacgaagg cgatctccag cagcttgttg taaaccgtct
    23701 cccatggtct tgatgctata taagaatagc cccagaccac ctaaaaagtg aaataaaatt
    23761 tcctgccaat taatggacat ttctttttcc tccgaaaaat aatcgcggaa tatctcctat
    23821 tctattttaa aggataaaag taaatctaac aagtgttaat gtcaagtttg taaaagaaaa
    23881 ttataattga taagtgtatt atttttaaga gtttttaacc ttattttaga tttgtgcaaa
    23941 cagttattgt tttttgtcta aaaatgtttt aggataaaaa tgtgattatc atggttctag
    24001 agtttgataa aaaactacag aatataaagc actttcttga aaacaacaaa atcaatcttt
    24061 taggaggaga aaatgaagaa tccatttttt gaaagacgtt gtcgttacag tattcgtaag
    24121 ttatcagtag gagcctgctc gctgatgatt ggtgctgttt tatttgctgg tccagccttg
    24181 gctgaagaaa ctgcagttcc tgaaaatagc ggagctaata cagagcttgt ttcaggagag
    24241 agtgagcatt cgaccaatga agctgataag cagaatgaag gggaacatgc tagagaaaac
    24301 aagctagaaa aggcagaagg agtagcgata gcatctgaaa ctgcttcgcc agcaagcaat
    24361 gaagctgcaa ctactgaaac tgcagaagca gctagcgcag ctaaaccaga ggaaaaagca
    24421 agtgaggtgg ttgcagaaac accatctgca gaagcaaaac ctaagtctga caaggaaaca
    24481 gaagcaaagc ccgaagcaac taaccaaggg gatgagtcta aaccagcagc agaagctaat
    24541 aagactgaaa aagaagtcca gccagatgtc cctaaaaata cagaaaaaac attaaaacca
    24601 aaggaaatca aatttaattc ttgggaagaa ttgttaaaat gggaaccagg tgctcgtgaa
    24661 gatgatgcta ttaaccgcgg aactgttgtc ctcgcttcac gtcggacagg tcatttagtc
    24721 aatgaaaaag ctagcaagga agcaaaagtt caagccttat caaacaccaa ttctaaagca
    24781 aaagaccatg cttctgttgg tggagaagag ttcaaggcct atgcttttga ctattggcaa
    24841 tatctagatt caatggtctt ctgggaaggt ctcgtaccaa ctcctgacgt tattgatgca
    24901 ggtcaccgta acggggttcc tgtatacggt acactcttct tcaactggtc taatagtatt
    24961 gcagatcaag aaagatttgc tgaagctttg aagcaagacg cagatggtag cttcccaatt
    25021 gcccgtaaat tggtagacat ggccaagtat tatggctatg atggctattt catcaaccaa
    25081 gaaacaactg gagatttggt taaacctctt ggagaaaaga tgcgccagtt tatgctctat
    25141 agcaaggaat atgctgctaa ggtaaaccat ccaatcaagt attcttggta cgatgccatg
    25201 acctataact atggacgtta tcatcaagat ggtttgggag aatacaacta ccaattcatg
    25261 caaccagaag gagataaggt tccggcagat aacttctttg ctaactttaa ctgggataag
    25321 gctaaaaatg attacactat tgcaactgcc aactggattg gtcgtaatcc ttatgatgta
    25381 tttgcaggtt tggaattgca acagggtggt tcctacaaga caaaggttaa gtggaatgac
    25441 attttagacg aaaatgggaa attgcgcctt tctcttggtt tatttgcccc agataccatt
    25501 acaagtttag gaaaaactgg tgaagattat cataaaaatg aagatatctt ctttacaggt
    25561 tatcaaggag accctactgg ccaaaaacca ggtgacaaag attggtatgg tattgctaac
    25621 ctagttgcgg accgtacgcc agcggtaggt aatactttta ctacttcttt taatacaggt
    25681 catggtaaaa aatggttcgt agatggtaag gtttctaagg attctgagtg gaattatcgt
    25741 tcagtatcag gtgttcttcc aacatggcgc tggtggcaga cttcaacagg ggaaaaactt
    25801 cgtgcagaat atgattttac agatgcctat aatggcggaa attcccttaa attctctggt
    25861 gatgtagccg gtaagacaga tcaggatgtg agactttatt ctactaagtt agaagtaact
    25921 gagaagacca aacttcgtgt tgcccacaag ggaggaaaag gttctaaagt ttatatggca
    25981 ttctctacaa ctccagacta caaattcgat gatgcagatg catggaaaga gctaaccctt
    26041 tctgacaact ggacaaatga agaatttgat ctcagctcac tagcaggtaa aaccatctat
    26101 gcagtcaaac tatttttcga gcatgaaggt gctgtaaaag attatcagtt taacctagga
    26161 caattaacta tctcggacaa tcaccaagag ccacaatcgc cgacaagctt ttctgtagtg
    26221 aaacaatctc ttaaaaatgc ccaagaagcg gaagcagttg tgcaatttaa aggcaacaag
    26281 gatgcagatt tctatgaagt ttatgaaaaa gatggagaca gctggaaatt actaactggc
    26341 tcatcttcta caactattta tctaccaaaa gttagccgct cagcaagtgc tcagggtaca
    26401 actcaagaac tgaaggttgt agcagtcggt aaaaatggag ttcgttcaga agctgcaacc
    26461 acaacctttg attggggtat gactgtaaaa gataccagcc taccaaaacc actagctgaa
    26521 aatatcgttc caggtgcaac agttattgat agtactttcc ctaagactga aggtggagaa
    26581 ggtattgaag gtatgttgaa cggtaccatt actagcttgt cagataaatg gtcttcagct
    26641 cagttgagtg gtagtgtgga tattcgtttg accaagccac gtaccgttgt tagatgggtc
    26701 atggatcatg caggggctgg tggtgagtct gttaacgatg gcttgatgaa cactaaagac
    26761 tttgaccttt attataaaga tgcagatggt gagtggaagc tagctaagga agtccgtggt
    26821 aacaaagcac acgtgacaga tatcactctt gataaaccaa tcactgctca agactggcgc
    26881 ttgaatgttg tcacttctga caatggaact ccatggaagg ctattcgtat ctataactgg
    26941 aaaatgtatg aaaagcttga tactgagagt gtcaatattc cgatggccaa ggctgcagcc
    27001 cgttctctag gcaataacaa ggtacaagtt ggctttgcag atgtaccggc tggagcaact
    27061 attaccgttt atgataatcc aaattctcaa actccgctcg caaccttgaa gagcgaagtt
    27121 ggaggagacc tagcaagtgc accattggat ttgacaaatc aatctggtct tctttattat
    27181 cgtacccagt tgccaggcaa ggaaattagt aatgtcctag cagtttccgt tccaaaagat
    27241 gacagaagaa tcaagtcagt cagcctagaa acaggaccta agaaaacaag ctacgccgaa
    27301 ggggaggatt tggaccttag aggtggtgtt cttcgagttc agtatgaagg aggaactgag
    27361 gacgaactca ttcgcctaac tcacgcaggt gtatcagtat caggttttga tacgcatcat
    27421 aagggagaac agaatcttac tctccaatat ttgggacaac cagtaaatgc taatttgtca
    27481 gtgactgtca ctggccaaga tgaagcaagt ccgaaaacta ttttgggaat tgaagtaagt
    27541 caggaaccga aaaaagatta cctagttggt gatagcttag acttgtctga aggacgcttt
    27601 gcagtggctt atagcaatga caccatggaa gaacattcct ttactgatga gggagttgaa
    27661 atttctggtt acgatgctca aaagactggt cgtcaaacct tgacgcttca ttaccaaggc
    27721 catgaagtta gctttgatgt tttggtatct ccaaaagcag cattgaacga tgagtacctc
    27781 aaacaaaaat tagcagaagt tgaagctgct aagaacaagg tggtctataa ctttgcttca
    27841 tcagaagtaa aagaagcctt cttgaaagca attgaagcgg ccgaacaagt gttgaaagac
    27901 catgaaacta gcacccaaga tcaagtcaat gaccgactta ataaattgac agaagctcat
    27961 aaagctctga atggtcaaga gaaatttaag gaagaaaaga cagagcttga tcgcttaaca
    28021 ggtgaggttc aagaactctt ggctgccaaa ccaaaccatc cttcaggttc tgccctagct
    28081 ccgcttcttg agaaaaacaa ggccttggtt gaaaaagtag atttgagtcc agaagagctt
    28141 gcaacagcga aacagagtct aaaagatctg gttgctttat tgaaagaaga caagccagca
    28201 gtcttttctg atagtaaaac aggtgttgaa gtacacttct caaataaaga gaagactgtc
    28261 atcaagggtt tgaaagtaga gcgtgttcaa gcaagtgctg aagagaagaa atactttgct
    28321 ggagaagatg ctcatgtctt tgaaatagaa ggtttggatg aaaaaggtca agatgttgat
    28381 ctctcttacg cttctattgt gaaaatccca attgaaaaag ataagaaagt taagaaagta
    28441 tttttcttac ctgaaggcaa agaggcagta gaattggctt ttgaacaaac ggatagtcat
    28501 gttatcttta cagcaccaca ctttactcat tatgcctttg tttatgaatc tgctgaaaaa
    28561 ccacaacctg ctaaaccagc accacaaaac aaagtccttc caaaacctac ttatcaaccg
    28621 gcttctgatc aacaaaaggc tcctaaattg gaagttcaag aggaaaaggt tgcctttcat
    28681 cgtcaagagc atgaaaatgc tgagatgcta gttggggaac aacgagtcat catacaggga
    28741 cgagatggac tgttaagaca tgtctttgaa gttgatgaaa acggtcagcg tcgtcttcgt
    28801 tcaacagaag tcatccaaga agcgattcca gaaattgttg aaattggaac aaaagtaaaa
    28861 acagtaccag cagtagtagc tacacaggaa aaaccagctc aaaatacagc agttaaatca
    28921 gaagaagcaa gcaaacaatt gccaaataca ggaacagctg atgctaatga agccctaata
    28981 gcaggcttag ccagcctcgg tcttgctagt ttagccttga ccttgagacg gaaaagagaa
    29041 gataaagatt aaatatcgaa aaatcttgtg aaatctttcc ttatatttcc aaagtgtgat
    29101 ataatagttt tgaataaaat aaataaagga gtttttgtaa catggcaaaa cttactgtta
    29161 aagacgttga cttgaaaggt aaaaaagtcc tcgttcgtgt tgacttcaac gtaccattga
    29221 aagatggcgt aatcactaac gataaccgta tcacagcagc tcttccaact attaagtaca
    29281 tcatcgaaca aggtggacgt gcaattcttt tctctcacct tggacgtgtg aaagaagaag
    29341 ctgataaagc tggcaaatca cttgctcctg tagcagctga cttggcagca aaacttggtc
    29401 aagatgttgt tttcccaggt gtcactcgtg gtgctgaatt ggaagcggca atcaacgctc
    29461 ttgaagatgg acaagttctc ttggttgaaa acactcgtta cgaagatgtt gacggcaaga
    29521 aagaatctaa aaacgatcct gaacttggta aatactgggc atcacttgga gatggtatct
    29581 tcgtaaacga tgcattcggt acagctcacc gtgcacacgc atctaacgtt ggtatctcag
    29641 caaacgttga aaaagcagtt gctggtttcc ttcttgaaaa cgaaattgcc tacatccaag
    29701 aagcagttga aactccagaa cgtccattcg tggctatcct tggtggttca aaagtttcag
    29761 acaagatcgg tgttatcgaa aacttgcttg aaaaagctga taaagtcctt atcggtggtg
    29821 ggatgactta cacattctac aaagcacaag gtatcgaaat cggtaactca cttgtagaag
    29881 aagacaaatt ggatgttgcg aaagctcttc ttgaaaaagc aaatggtaaa ttgatcttgc
    29941 cagttgactc aaaagaagct aacgcatttg ctggttacac tgaagtgcgt gacactgaag
    30001 gtgaagcagt ttctgaaggc ttccttggtc ttgacatcgg tccaaaatct atcgccaaat
    30061 ttgacgaagc tttgactggt gccaaaacag ttgtatggaa cggacctatg ggtgtatttg
    30121 aaaacccaga tttccaagct ggtacaatcg gtgtgatgga cgctatcgtg aaacaaccag
    30181 gagttaaatc aatcatcggt ggtggtgact cagctgccgc agcgattaac cttggccgtg
    30241 cagacaagtt ctcatggatt agtacgggtg gtggagcatc aatggaactt cttgaaggta
    30301 aggttcttcc aggacttgca gccttgacag aaaaataaga ttttataaat aaatcaaaga
    30361 agagagggat gaaagttcct cttttctttt gcttaaaata aaaacgcttc ctctcaacta
    30421 ttactcataa aaatcaccga tttgtgataa aatggaaata gaaagttgag attatgagtt
    30481 attttaaaaa atataaattc gataaatccc agttcaaact tggtatgcga acctttaaaa
    30541 caggtattgc tgtttttcta gttctcttga ttttttgctt ttttggctgg aaaggtcttc
    30601 aaattggtgc tttgacagcc gtttttagcc tgagggagag ttttgatgag agtgttcatt
    30661 ttgggacttc gcgtattcta ggaaatagta tcggtggact ctatgccttg gtcttcttct
    30721 tattaaatac ctttttccac gaagcctttt gggtgacctt ggtagttgtt ccaatctgca
    30781 ccatgttaac cattatgaca aatgtagcaa tgaataacaa agcaggggtt attggtggtg
    30841 tagcagctat gttaatcatt accctatcaa ttccaagtgg tgagacaatt tcgtacgtgt
    30901 ttgtgcgtgt atcagaaacg tttatgggag tttttgtcgc aattatcgta aattacgata
    30961 ttgatcgtat tcgtctcttt ttagagaaaa aagaaaaata atgttacatt ttataacatt
    31021 atcaattgac gtttgtcttt ttttagacta taatagacag aaagaaggaa attgtaaatg
    31081 aaggaaaaag aatttcgccg aaatatggct gtttttccta tcggcagtgt tatgaagttg
    31141 accgatctat cggcgcgtca gattcgttat tatgaagatc aagagttgat caagcccgat
    31201 cgaaacgaag gaaatcgtcg catgtattcc ttgaatgaca tggatcgtct gcttgaaatc
    31261 aaagattata tctctgaagg ttataatatc gctgccatta agaaaaaata tgctgaacgt
    31321 gaagcgaaat ccaagaaagc ggttagtcag actgaagtac gtcgtgcact tcacaatgaa
    31381 ctcctccaac aggggcgttt tgcttcagta cagtcacctt ttggtcgcgg ttaggcaacc
    31441 gcaagtagtc atagattaag gagaaaactt atgccaatca cagctgcaga tattcgtcgt
    31501 gaagtcaagg aaaaaaatgt tacctttatt cgtcttatgt tctcagatat tttgggaacc
    31561 atgaaaaacg tcgaaattcc tgctacagat gaacagttag ataaggtctt gtcgaacaag
    31621 gttatgtttg atggatcttc tattgaaggt tttgtacgta tcaatgagtc ggatatgtac
    31681 ttgtacccgg acttggatac atggacagtc ttcccttggg gagatgaaaa tggaagtgtt
    31741 gcaggtctga tctgtgatgt ttatacaaca gaaggtgaac catttgcggg tgaccctcgt
    31801 ggtaatttga aacgagctct tcgtcacatg gaagaagttg gattcaaatc cttcaacctt
    31861 ggtccagagc cagaattctt cctatttaag ttggatgaaa atggggaccc aacacttgaa
    31921 gtgaatgaca agggtggcta ctttgatttg gcacctactg accttgcgga caacacacgt
    31981 cgtgagattg tgaatgtctt gaccaaaatg ggatttgaag tagaagcgag tcaccacgag
    32041 gttgcggttg gacagcatga gattgacttt aagtacgatg aagttctccg tgcttgtgat
    32101 aagattcaaa tctttaaact tgttgttaaa accattgctc gcaaacacgg actttacgca
    32161 acatttatgg cgaagccaaa atttggtatt gctggctcag gtatgcactg taatatgtcc
    32221 ttgtttgatg cagaaggaaa taacgccttc tttgatccaa atgatccaaa aggaatgcag
    32281 ttgtcagaaa cagcttacca tttcctaggc ggtttgatca agcatgctta caactatact
    32341 gccatcatga acccaacagt taactcatac aaacgtttgg ttccaggtta tgaagcgcct
    32401 gtttacattg cttgggctgg tcgtaaccgt tcgccacttg tgcgcgtacc tgcttcacgt
    32461 ggtatgggaa ctcgtcttga gttgcgttca gtggatccaa tggcgaaccc ttacattgct
    32521 atggctgttc ttttggaagt tggtttgtat ggtattgaaa ataaaatcga agcaccagct
    32581 cctatcgaag aaaatatcta catcatgaca gcagaagagc gcaaggaagc tggtattaca
    32641 gaccttccat caactcttca caacgctttg aaagctttga cagaagatga agtggttaaa
    32701 gctgctctcg gagatcacat ctacactagc ttccttgaag ccaaacgaat cgaatgggca
    32761 agttatgcaa ccttcgtttc acaatgggaa attgataatt atttagacct ttactaatat
    32821 agaagaaaga ttgcctgtgg gtaaacagtc acacagcagt ctaagccatc aaatacctat
    32881 aacccttaaa atagcgattt cggtcgctat ttatttttcg aaaaatcctc ttgactcttt
    32941 tgcgaattag atttatcatc agacgtgtag aagaaaatca aggagtcact atggaaaaat
    33001 tcaatttcaa aaacaatatc gggcaagaaa acaagttact tcaaatcgaa atctacaagt
    33061 ttactaactt ttgcaagctt caaaattaca catctgtaaa tattttttcg aaagatatat
    33121 ttgaagccat agtaaattga gactagaata gtacactaca tctgctaaaa atttctagaa
    33181 attaatttaa ctttcctaat cgatttgttt acatcttatt tcaatctact atattatctc
    33241 aataaatgat gatggcgact gttttgtttg tgcttgtcga tttttgaatc ctgatcgagc
    33301 ggaagaatat ttctgccgag gttgtcaagg ggaaaatcct gaagatattg aattttatga
    33361 tgaacaatta caggcagaaa aggtggaggc tttgaatatt cgattggaag taaaaaattg
    33421 aattatctac aatctcatca acaataaacc tatttcaacc ccattatcta taggcgtatt
    33481 tttacgcctt tttatatact tgaagcacat aagaaacatt atgggaagtt tgctgatgga
    33541 agcactcaag aaattgatgt tccttatgat attcctgata cttgggagtg ggtgaggata
    33601 aaatcaattt attggaattt tgggcaaaat aagccagaga aatcctttag gtatatagat
    33661 acgtctagta ttgatagaaa aaagaacata atcaactaca aaaatctaca atatctttca
    33721 cctgaacaag cgccttcccg tgctagaaaa ttagtttcgc agaatagtgt cttattttca
    33781 acagttagac catatctaaa aaatattgct gtagttagag aacttaaaga gtatttgata
    33841 gctagtacag catttattgt tttggatact ttacttaacg aaacatattt gaaatattat
    33901 ttattatcag ataattttat caatcgtgtt aataataaat ctactggaac aagttatcct
    33961 gcaatcaatg attataattt taatctatta ttaatt
//
LOCUS       DAVAGB010000021        32889 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVAGB010000021 DAVAGB010000000
VERSION     DAVAGB010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32889
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.021"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            <1..865
                     /locus_tag="VQO19_001097"
     CDS             <1..865
                     /locus_tag="VQO19_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET1349377.1"
                     /translation="NYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNID
                     QILVERKRDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQK
                     PILLLEQIIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLE
                     NVIKTSSNLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIK
                     IQKNNECLNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTI
                     EKWLSKSQQLL"
     gene            complement(941..2503)
                     /gene="guaA"
                     /locus_tag="VQO19_001098"
     CDS             complement(941..2503)
                     /gene="guaA"
                     /locus_tag="VQO19_001098"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HET1349378.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            2645..3343
                     /locus_tag="VQO19_001099"
     CDS             2645..3343
                     /locus_tag="VQO19_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET1349379.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(3386..4282)
                     /locus_tag="VQO19_001100"
     CDS             complement(3386..4282)
                     /locus_tag="VQO19_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET1349380.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLSYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQANIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(4291..5226)
                     /locus_tag="VQO19_001101"
     CDS             complement(4291..5226)
                     /locus_tag="VQO19_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HET1349381.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYSGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQTFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(5223..5948)
                     /locus_tag="VQO19_001102"
     CDS             complement(5223..5948)
                     /locus_tag="VQO19_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HET1349382.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(6032..6667)
                     /locus_tag="VQO19_001103"
     CDS             complement(6032..6667)
                     /locus_tag="VQO19_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HET1349383.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKMIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQDL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(6669..7496)
                     /locus_tag="VQO19_001104"
     CDS             complement(6669..7496)
                     /locus_tag="VQO19_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET1349384.1"
                     /translation="MMIKIIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(7518..7853)
                     /locus_tag="VQO19_001105"
     CDS             complement(7518..7853)
                     /locus_tag="VQO19_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HET1349385.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEGGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(7854..8570)
                     /locus_tag="VQO19_001106"
     CDS             complement(7854..8570)
                     /locus_tag="VQO19_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HET1349386.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPAEVMDAIKEAGYHVLDLAHNHILDSQIEGVISTADII
                     EKAGITPIGVYTHEQRDQAPLVIKEVNGIKVALLAYSYGFNGIEQYISQEDYNRYLLD
                     LNEDKMKAEVERAEKEADITIIMLQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSETVEKDGDKKLIIY"
     gene            9083..9694
                     /locus_tag="VQO19_001107"
     CDS             9083..9694
                     /locus_tag="VQO19_001107"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET1349387.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            9739..10467
                     /gene="rlmB"
                     /locus_tag="VQO19_001108"
     CDS             9739..10467
                     /gene="rlmB"
                     /locus_tag="VQO19_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HET1349388.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKNEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(10506..11417)
                     /gene="trxB"
                     /locus_tag="VQO19_001109"
     CDS             complement(10506..11417)
                     /gene="trxB"
                     /locus_tag="VQO19_001109"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HET1349389.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQVFGGVFIYVGLDPLGDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(11483..11707)
                     /locus_tag="VQO19_001110"
     CDS             complement(11483..11707)
                     /locus_tag="VQO19_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HET1349390.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(11785..12528)
                     /locus_tag="VQO19_001111"
     CDS             complement(11785..12528)
                     /locus_tag="VQO19_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET1349391.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(12528..13328)
                     /locus_tag="VQO19_001112"
     CDS             complement(12528..13328)
                     /locus_tag="VQO19_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET1349392.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(13486..13842)
                     /locus_tag="VQO19_001113"
     CDS             complement(13486..13842)
                     /locus_tag="VQO19_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET1349393.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(13836..14366)
                     /locus_tag="VQO19_001114"
     CDS             complement(13836..14366)
                     /locus_tag="VQO19_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HET1349394.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNNRRRSTC"
     gene            complement(14366..14860)
                     /locus_tag="VQO19_001115"
     CDS             complement(14366..14860)
                     /locus_tag="VQO19_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET1349395.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            14995..15441
                     /locus_tag="VQO19_001116"
     CDS             14995..15441
                     /locus_tag="VQO19_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HET1349396.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVDQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            15438..16085
                     /locus_tag="VQO19_001117"
     CDS             15438..16085
                     /locus_tag="VQO19_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HET1349397.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(16106..16687)
                     /gene="pdxT"
                     /locus_tag="VQO19_001118"
     CDS             complement(16106..16687)
                     /gene="pdxT"
                     /locus_tag="VQO19_001118"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HET1349398.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(16688..17563)
                     /gene="pdxS"
                     /locus_tag="VQO19_001119"
     CDS             complement(16688..17563)
                     /gene="pdxS"
                     /locus_tag="VQO19_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HET1349399.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(17715..19094)
                     /locus_tag="VQO19_001120"
     CDS             complement(17715..19094)
                     /locus_tag="VQO19_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET1349400.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAER"
     gene            19388..20311
                     /locus_tag="VQO19_001121"
     CDS             19388..20311
                     /locus_tag="VQO19_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HET1349401.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            20371..20976
                     /locus_tag="VQO19_001122"
     CDS             20371..20976
                     /locus_tag="VQO19_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET1349402.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEETDGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            20995..22239
                     /locus_tag="VQO19_001123"
     CDS             20995..22239
                     /locus_tag="VQO19_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET1349403.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISVSLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGNADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(22355..22612)
                     /locus_tag="VQO19_001124"
     CDS             complement(22355..22612)
                     /locus_tag="VQO19_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HET1349404.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEKGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(22654..24690)
                     /locus_tag="VQO19_001125"
     CDS             complement(22654..24690)
                     /locus_tag="VQO19_001125"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HET1349405.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQSVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLILSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(24914..25831)
                     /gene="glyQ"
                     /locus_tag="VQO19_001126"
     CDS             complement(24914..25831)
                     /gene="glyQ"
                     /locus_tag="VQO19_001126"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HET1349406.1"
                     /translation="MSKKLTFQEIILTLQRFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(26025..26786)
                     /locus_tag="VQO19_001127"
     CDS             complement(26025..26786)
                     /locus_tag="VQO19_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET1349407.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIIGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(27059..27901)
                     /locus_tag="VQO19_001128"
     CDS             complement(27059..27901)
                     /locus_tag="VQO19_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HET1349408.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSITTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(28015..29406)
                     /locus_tag="VQO19_001129"
     CDS             complement(28015..29406)
                     /locus_tag="VQO19_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HET1349409.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(29641..30018)
                     /locus_tag="VQO19_001130"
     CDS             complement(29641..30018)
                     /locus_tag="VQO19_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET1349410.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKICQREGDTHQSYKHIAPV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            30251..31228
                     /locus_tag="VQO19_001131"
     CDS             30251..31228
                     /locus_tag="VQO19_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET1349411.1"
                     /translation="MLKLGVIGTGAISHHFIEASHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            31225..32307
                     /locus_tag="VQO19_001132"
     CDS             31225..32307
                     /locus_tag="VQO19_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET1349412.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSKT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLIYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKVILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(32371..>32889)
                     /locus_tag="VQO19_001133"
     CDS             complement(32371..>32889)
                     /locus_tag="VQO19_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET1349413.1"
                     /translation="VRLMYQDEAGFGRISKLGSCWAPIGVGPHIHSHYIREFRYCYGA
                     VDAHTGASVFLIAGGCNTEWMNVFLEELSQAYPYDYFLLVIDNAIWHKSSTLKIPTNI
                     GFAFIPPYTPEMNPIEQVWKEIRKRGFKNKAFRTLEDVMNQLQDVIQGLEKEVIKSIV
                     NRRWTRMLFESR"
BASE COUNT         9856 a         7314 c         5874 g         9845 t
ORIGIN      
        1 gaactataaa cgatggtcta attcaaaaaa gggattattg aacaatcatc aaaacattta
       61 cttttattca aagtcaaaag attttaaatt taatacaatt tttacagagt attcttctac
      121 tacaaatatc gaccaaatac tagtggaacg aaaacgagat ggaaactcta aaactatata
      181 taaagttgat aataatggta actatattct agcaaaagag aaaaatggag ttcccctttc
      241 agatgtttgg aatataccat ttcttaatcc aaaagctaaa gaaagagtag gttatcctac
      301 acaaaaacct attctgttat tagaacaaat tataaagatt gctactgata aaaatgatat
      361 agttttagac ccgttctgtg gaagtggaac tactttagta gcctccaaga ttttgaatag
      421 aaattatatg gggattgatt tatctgagga agctatcaat ataactcagc aacgtctgga
      481 aaatgttata aaaacaagtt caaatttatt gaataaagga atcgaagcat atagaaccaa
      541 aactgaggaa gaggaaaaca ttcttaaatt attacaggca aaaattgttc aaagaaataa
      601 aggaattgat ggttttttac ctaaacattt tcaaaaaaaa ccgataccta taaaaattca
      661 aaaaaataat gaatgtctga atgagagtat ctctttatta cagaatgcta taaactccaa
      721 aaaacttgat tttggagtag ttataaaaac tcattcagat aatttattat ttgattttga
      781 tacgattcct gaaaatataa tagtagttga ccattttgaa cttacaatcg aaaaatggtt
      841 aagtaaaagt caacagttac tatagtttgc aaattattta cagaaagaac aaaaaatgct
      901 ctgaaacact gatttcaaag cattttttgt tagtttaaaa ttactcccac tcaactgttg
      961 caggtggttt acttgtaata tcgtagacga tacggttaac atgatccact tcatttacga
     1021 tacgtactga gattttttga agtacttccc atggaatttt ggcaaaatca gcagtcatac
     1081 catcgataga agtgatagca cggattgcaa tcgtgtagtc atacgtacga ccgtcaccca
     1141 taacaccgac tgaacgaacg cctgtgttaa cagtgaagta ttgccaaata tcgcggtcaa
     1201 gtccagcttt agcgatttct tcacgaagaa tagcgtctga ttcacgaacg gtttcaagtt
     1261 tctcttcagt gatttcaccc atgacacgga tagcaagtcc tggtcctggg aatggttggc
     1321 gccatacgat atggtctggc ataccaagct ctgtaccaag agcacgaact tcatccttgt
     1381 aaagagtatt aagtggttca atcaattcaa actgcatatc ttctggaaga ccacccacgt
     1441 tgtggtgtga cttgatagtt tgagctgtat ccgtaccaga ctcgataaca tctgtgtata
     1501 aagtaccttg agcaaggaat ttcacatctt tgagcttgct tgcttcgtca tcgaatacat
     1561 agacaaactc gttaccgatg attttacgtt tttgttcagg atcagaaacg ccagcaagtt
     1621 tgtcaaggaa acgtttagca gcgtctgctt tgacgatatt caaaccaaac ttaccaccga
     1681 gcatgtccat aacttgatca gcttcgcctt tacgaagaag accgtggtct acgaagatac
     1741 agatcaattg atcgccaatc gctttttgga gaagaacccc aacgacagat gagtcaacac
     1801 cacctgatag accaagaagg acacgtttat caccgacggt ttcacgaatt tttttgatct
     1861 gcatgtcaat gaaattatcc attgaccagt cacctttagc cttacaaatg ttaagggcaa
     1921 agttacgaag gatatcattt ccgtatacag aatgacgaac ttctgggtgg aattggatac
     1981 cgtaaatgtg tttatctggg ttttcgatgg ctgcgtatgg gcagtcagct gatgtacctg
     2041 tacgaacaaa gtcagcagga atctcagtaa ccgcatcacc atggctcatc aaaacagtct
     2101 gttcatcagg tgttgattca aaaagcgctg atggtgtgtg agttagggtt gattgaccgt
     2161 attcacgatt tccagcatca cctgcaggaa caacttttcc tccaagttta tgggtcaata
     2221 actgcatacc ataacagatt cccaaaattg gaattccgag ttcgaagatt tctgggtcaa
     2281 tatcaaatga accatcttca tatacagaat ttggaccacc tgatagaata attcctacag
     2341 gattgacttc acgaacttca gcagctgaaa ttttatggct ttttagttct gaaaaaacac
     2401 caatctcacg gatacggcgt gaaatcagct ggttgtactg gctaccatag tccaatacga
     2461 tgattttttc tacatcttgc aaatcagttg aaatgttgct catctttttc ctttctcaaa
     2521 agaaatatct tttctcaata ttctatcaca aataagggcg aattaccaac taaacaaggc
     2581 gaagtttgac tttttctagt ttattggggt acaatagaga aaagatagaa atgaagtgaa
     2641 aaatatgcta cctgcttata tgaaaatcca tgatcagata aaaaaggata ttgacgagca
     2701 ccgttgggct attggtgaga ggcttcccag tgaaagagat ttagctgagc agtttgcggt
     2761 cagtcgcatg accctccgcc aagccgtatc tctattagtc gaagaaggcg tcttagagcg
     2821 ccgtgtagga agcggcacct ttgtttccag tactcgagta caagaaaaga tgcgagggac
     2881 aaccagtttt actgaaattg tcaaatccca aggtaaagtt ccctctagcc agctcatttc
     2941 ctacaaaaaa accattccca atgagcaaga agttgccaag ctaggaattt ttccaacgga
     3001 caatattatc cgaatggagc gggtccgcta tgccgaccaa gttcccctag tttatgaagt
     3061 tgcttctatt cctgaaaaat tcattaagga ctttaaaaaa gaagaaatca ccagtcattt
     3121 cttccaaacc ttgcagaaac atggctatcg tatcggcaaa tctcaacaga ccatctatgc
     3181 tcgccttgct aaagaaaaga ttgcccacta tttggaagtt gaaaaaggac atgctattct
     3241 tggattgaca caggtttcct acctagaaga tggtactgct tttgaatacg taaaaagtca
     3301 atatgtaggc gaacgctttg aattttatct tgaaaataat tagattacca cgcaaaaact
     3361 ctctgtcaca gacaaagagt cttttttatt tttctaagaa taaatctttc aaagaaatca
     3421 aagttacagc aaacaatatc attgccatac caagaaaatc aatgggataa aattgttcat
     3481 tcattattaa gaaggcaaag aaaaccgccg atattggctc aattgaagcc aacaagcttg
     3541 acttgaccgg tcctatcaga ctggctcctt taaggaaagc tgtataggca aagacagtcc
     3601 cgataaggat aatgcctgca aacgcaagga gaaaatcaag actagtcggg atattggcct
     3661 gtagaacccc tgtaaaagga agggcgacca aacctgctat aaccattccc acaccaatga
     3721 ccaagctact cccccacttt ttaatcaagg ctatgggtaa aatgatatat agagcataag
     3781 tcaaggcaga aaagagaccc cagaacaggc cagcaggtgt catggataac tggtccaact
     3841 gcccatgtgt tgcgatcagg aaggttcctc cgatggcgaa tatgatggaa actatctctc
     3901 ccagtgtcgg tgccacccta tccttgatac agctataaat taaaattccg acaggacaaa
     3961 catactgaag caccgtcgct gttcccgcat tggtctcctg aatagcagac agataggcga
     4021 attggttgag aaaaagacca atcagagcaa aaataagaag agacagcaaa ctctttctat
     4081 cctttaaaaa gaccagtatt ttatcctttg cagtagcata agacaagagc atgagaattc
     4141 caccagcgat taaaagacgc aagttggtca agaccagagc cgaaattccg tgtgccatta
     4201 ggtattggcc actcgttcct gacaaccccc aagcaatacc agccacaact gttagtaaag
     4261 tcccttttaa actatttgac atgtctctcc ttactcttct ttgcgaatca agttcatcac
     4321 ttgattgcgg tctaatatcc attgagctct ctcgtccttt tcataggtac gattcgatag
     4381 gaaaatagtg gcttcttgct tctgacgatt ccacatgata aaggtacctg tatagcccgt
     4441 atggtctagc caatctcctt ccaaattcca tgctaaagaa cgttccttgt catccaaagg
     4501 agaaaaattt tgatttaagt ctcttgcaaa atcatctgct aaatagtgtt ctaaaaaggt
     4561 ttgtaaatcc tttatagtcg aaaataaacc agcactccca gcatgtctac ccaggagacg
     4621 agccttggga tcatgcacta tgcctgcctc tacacctcta actgttggaa cagcaagctc
     4681 aactggccca aacttagttt ccgtcattcc ccaaggtttc cagacttgat cctttaaaat
     4741 cacatccaaa tcttgattaa aaattctttc caaaataaag cccaacagca aaaaatggac
     4801 atccgaataa agaaaggctg gctgacttcg tctgttgaga tgaaacatcg cttcctttaa
     4861 ttcaggggct gttaaaagat cacgattagg aataaaagga tcaaggtctg ttgcatgagt
     4921 caagagctgg cgaatagtga tgtctggata atcactctca ggtaaaaaat ctattaccag
     4981 tctatcaata tctaattgac ctatttccca caagaaggta caaactgtgc caaccccaac
     5041 aaccttactg acactagcta ggtcataaac tagtcctgcc tcagtctgca agccatgctc
     5101 tgggtcactc tggcctgaat agaactctgt ccattgattg tccttaaaat acgcaaaaga
     5161 ggctccggga taaatccctg cctcgatttg ttcttctatt tttttaataa tcttggtcca
     5221 cttcatactt cttcaaacca caattcaaca ttatttctat ctttaccaag gaagaatttt
     5281 tcagacttag gaataaaata ttcagtagac tcaaacttct ggcgaagact tgctatgtct
     5341 aattcattga ccaagaactt gagcatagat aagtcccagg taaccgtatt gtccacagtc
     5401 aaatcctgcc cctgagctgg aataaaatca agggatgccc caatttcaga tgattccaag
     5461 aaactttcga tatcagttgg gagatgtaat tccatagaaa tctcaaattt acttaaagaa
     5521 attgatgcca aatctgtttg aaattcaggc ttttctccta cttctactag acttgctctg
     5581 tcatcttccg catgaatcaa aatcaaatca tcttctggtg agaaaatttc aaaagcgtag
     5641 ccattttgac ctttatataa tcgatgaatc gaatctgttt tagataagat tccttcaatt
     5701 tctaagggat tttccacctt gacaatcaat ctagctagtt tttttcttcc ctctacctta
     5761 cgagtacgca tactgggagc ttcttctaaa accagctttt caagacccgt ttggtcacct
     5821 agtgacagaa aggccgattc ttctaacaag gccttcattc caagggtttc aatataaaat
     5881 gtttcattta attttctatt attagctttt aaagtaggaa taatccgtac aatctgattt
     5941 acattcataa attcctccgt cactttttat tttaaaggat tttagaattt tttacaagat
     6001 attatgctca aatttcacat tatttagcta tttagtaaag atagtctttc aaggcttttg
     6061 acaaagcctg ataaccagca atactgaggt gcagtccatc agttgtatat tcttttttga
     6121 gttggcctgc ttggtctgtc aaacaatcaa atactggcac aaattccacc tgcatatagg
     6181 cagatgcaag atcttgatag gcttgattcc agttctgaat tttttcattc gagcggatat
     6241 agactgcctg ctgatactcc tctccctcat tgacaggtaa aatggaaagc aatttaatct
     6301 ctgtcaatgg ataatcgcga gcaacggatt gaatgatagc ttcgagatta ttgagagcct
     6361 cattcacagg aacatccttt ccgatatcat ttgtcccaat cagaagaaaa attttatcta
     6421 ctgctccacc atatagatga gcatcaaggt tctctagtaa cagtcctgtc tgatagccac
     6481 gaattcctcg attgacaatc atttttgaag tcccaaatag ctcctgtaga ggataatact
     6541 cgacaatgga atccccaata aaaagaatgt ttggttctac aacagaaatg tgatttaggt
     6601 gacgatactt ggtttgaatt ttttcttgtt cctttaggag ccaattttct aataactgta
     6661 ctgccacttc attctccttt ttctaaccag ttttccaaga cttgataaac tcctccttgg
     6721 ctattggctg gtgctagagc agtcgccaca gctttggctt tctcatcagc attttccatc
     6781 gcataggcaa ttccagccat ttcaagcatt tcaacatcat tttcactatc accaaaagcc
     6841 atgatttctt gggatttcaa gtcccagcgc ttgagtaatt cctccaagcc ccatgcttta
     6901 tgaatcccag cttggaggat atcaatgcaa ccatagccac tggatacagc tcggacacgg
     6961 ccatcaaaga gagcattgat ttcttccaaa accgaactca aacgttcctc accaacaacc
     7021 atgctcatct tgagcacacc accaaagagg tcagatgtta attcatccac aaattgcatc
     7081 cgttggtaga atttttcaat catttctgga gtcataaaac tttcaagatc tgtaaaaatc
     7141 gtaccttcct tgacaaaatc acccttcatc cccgttacaa caaactggtc ctgacacgct
     7201 cgacccttga aatgagccaa agccttgttg acaatggcgt catcccatgt ctgagcctga
     7261 atcaattcat tgttttcaaa aatacgagcg ccattagcaa caaccagaac cactcgatcc
     7321 accaagggac tcagtagttg tctcatgcgg tgaatttcat tgcccgtcgc aatgacaaaa
     7381 cgaatgcccc tttgatccaa ctgatctaaa atcttttcca atcgtgggag atcaagctga
     7441 cctctagcat ccagcaaggt cccatccata tctgtcgcaa ttatcttaat catcatttac
     7501 tttcctctgg attcaagcta ataccacttc aatcccacat gttcattcat ttctttatag
     7561 gctgtatcaa ttcgttcctt agtcgcttca tctaactggt cacgatgact gccaccctct
     7621 ataaaatctt ccaaaatata agtttggtaa tgatacaagg gatatccttc tggtgaaaag
     7681 gttccctttg gtgttcgatt gacccaagta ggatgagctt tagctgttcc gatagttgtt
     7741 tttccatcct tcttcttgat ggtgacatcc atgagaacac cacgttcagt ccacttagca
     7801 ttctcttcat ctcccataga ttcaatccgt tgattggaaa tgaagttccc catttaatag
     7861 ataatgagtt tcttatctcc atctttttca accgtttcag atggttcaac aacgtgagga
     7921 tgccctccaa agataatatc cgctccccaa tcgatcatct tgtgataaag agctttttgt
     7981 tcttcagttg gttccaatcg atactcaaca cccatctgaa gcatgataat ggtgatatct
     8041 gcttccttct ctgcccgttc aacttcagcc ttcatcttat cttcgtttaa atctaaaaga
     8101 taacgattat agtcttcctg agaaatatac tgctcaattc cattgaaacc ataggaatag
     8161 gctaacaatg caaccttgat accattcact tccttaatga ccagcggagc ctgatcacgt
     8221 tgttcgtgcg tataaactcc gattggagtg attccagctt tctcaataat atcggccgtt
     8281 gaaataactc cctcaatttg cgaatccaaa atatgattat gagctaaatc cagcacatga
     8341 taacctgctt ccttaatagc atccataact tcagcaggag cattaaagag aagataaccc
     8401 gctaaataat gatccttatt aatggttcct tcgaaatcac caatagctaa atctgcttgc
     8461 ttgagccaag gagtcacata ctcaaaattt tcatgaaagt cataggtacc gtcttctttt
     8521 ttagctgaaa agaaaagtcc atcgtggtag agcaaatccc cgtgggccat aattctggca
     8581 gttttttcct cttcctactc ctgagacttt tgcttagtcc cctcttgaga aatagtatct
     8641 cgtttttgac tagtcaaggg attccttgga agctttcaaa caacaagacc aagcccattg
     8701 ataaaccaac tgctagcaag agtatcgcca caaatccctt attgctccac ttgcgataac
     8761 tcctaaaaag tttaccaagc ccttcataaa acgaaaagct aaaccaccct gatttcgatt
     8821 ttgtcttctt tgtatcttcg ttctccctac tttcttatgc aagccttttc tttttattat
     8881 atcacagata agtatttctt tcacaattga attgaacttc ctatctattt tctataaatc
     8941 ctaaatgcca taatgctttc aattcttgtc attttgtgat atcatgtaga ggaaatgaac
     9001 taatccacag tggcttattc caagtatacc acttgggctt tggcagtagc taactgcact
     9061 aaacataata taaggagaga aaatgtctgc aatagaacgt attacaaaag ctgctcactt
     9121 aattgatatg aacgatatta tccgtgaagg gaatcctact ctacgcgcga ttgctgagga
     9181 agtcactttc cccctatctg accaggaaat catcctaggc gaaaagatga tgcaattcct
     9241 taaacattcc caagatcctg tcatggctga aaaaatggga ctccgcggtg gtgttggact
     9301 ggctgctccc cagttagata tctcaaaacg cattatcgct gttttggtac ctaatattgt
     9361 tgaagaaggc gaaactccac aggaagccta cgatttggaa gccattatgt acaatccaaa
     9421 aatcgtctct cactctgttc aagatgctgc tcttggcgaa ggagaaggtt gcctgtctgt
     9481 tgaccgtaac gtgcctggct atgttgttcg ccatgcccgc gttactgttg actactttga
     9541 caaagatgga gaaaaacacc gtatcaaact caaaggctac aactccattg ttgttcagca
     9601 tgaaattgac cacattaacg gtatcatgtt ttacgatcgc atcaatgaaa aagacccatt
     9661 tgcagttaaa gatggtttac tgattcttga ataaagaaaa tcccgttgca agacggggtt
     9721 ttgtgttata atagaggcat gaaaacaaat gatattgtct atggcgtcca cgccgttacc
     9781 gaagccctcc ttgcaaatac aggaaacaaa ctctacctcc aagaagatct ccgaggtaag
     9841 aatgttgaga aagtcaagga actagctaca gaaaagaagg tgtccatttc ttggacatca
     9901 aaaaaatctc tctctgagat tactgaaggt gctgttcatc aaggttttgt tctacgagtg
     9961 tctgaatttg cctatagcga gctagattac atccttgcaa aaacacgcca agaagaaaat
    10021 ccacttctat tgattctaga tggtctaacc gatccccata atctaggttc tatcttgcga
    10081 acagccgatg cgaccaatgt ttcaggtgtc atcattccca agcaccgtgc tgtcggagta
    10141 actcctgtcg ttgccaaaac agccacaggt gctattgaac acgttccaat tgcccgagtg
    10201 accaacctca gtcaaacctt agataaactt aagaatgaag gtttctggac ctttggaacg
    10261 gatatgaacg gtactccttg ccacaagtgg aatacaaaag ggaaaatcgc cctcatcatt
    10321 ggaaatgaag gaaaaggtat ctctagcaac ataaaaaaac aggtcgatga aatgattacc
    10381 attccgatga atggacatgt tcaaagcctt aatgccagtg ttgctgcggc cattctcatg
    10441 tacgaagttt tccgaaatag actataaaaa agtttccagt catctgattg gaaacttttt
    10501 tatgattaac tatgttctgt aatgaattta taggcttctt gaccagcgat agctccatct
    10561 ccaaccgctg ttgttacttg gcgaaggtct ttcaagcgaa catctccaac tgcaaagata
    10621 ccgtcgactg cagttttcat gtggttatct gtcacaatcc atcctgcctg atcttggata
    10681 ttcaattctt taacaaaatc gccaagaggg tccaatccaa catagataaa gacaccaccg
    10741 aagacttgtt ctgtcacttg acctgttttc acattttcaa atacgactga ttctactcgg
    10801 ttttcaccct tgatttccct tactacagaa tcccagataa agctgatttt ttcattcgca
    10861 aaggcgcgat cttgtaaaac cttttgggca cgaagttggt cacgacggtg aacaatggta
    10921 acagtcttag caaaacgagt caagaagagg gcttcttcaa cagctgaatc tccaccacca
    10981 actaccaata aatcttggtc acggaagaaa gcaccatcac acacagcaca gtaagaaaca
    11041 ccacgactgt tcagttcttc ttctccaggt actcccaaag gacggtgttt agaaccagtt
    11101 gctacgataa ctgtacgtgt ttcatatgtt tggtcatcag tcatcacttt cttaaaatca
    11161 ccatggtctt cgacattttc aacataacca taaatgtgct ccacaccaag attttcaagt
    11221 ggttcaaaca tcttttcagc caattcaggt ccactaatat tagcgtatcc tgggtaattt
    11281 tcgatatcag atgtattatt catctgacca cctggcagac caccttcaat caaagctact
    11341 tttagattgc ttcgagcagc atacaaggcc gcagtcatcc ctgcaggtcc agcaccgata
    11401 ataatagtat cgtacatata gattccttct ttcttgttgt aactatcttt attctaactc
    11461 tttcttgtca atcacgcaag gattatgcct tgaaaacaag aattaaactc ataaccgcaa
    11521 aggataatac tgggacaacc aagactccaa tcataatcat atcatagaga tgggcttggc
    11581 gagccctggc tgtcttatca actcccgaca tggctctcag accaatccaa atccctaaaa
    11641 aaatcagaac aaggatggtg gtcaagatca aactctcgaa atataaagaa aatagttgca
    11701 gtagcatgat ttctctcatt tctatctttt ttaaagagta aactcagcta gtccaactaa
    11761 ctgagttttc ctttatctat tatatcaaat ataagtccgt ttgtaactag cgaagaattc
    11821 ttttgtccgc tcttctttag gggtgtggat aatctcatcc ggtgttccag actcgatgat
    11881 tttcccctta tctaagaaga gaatcttatc agccacttgg gctacaaagg acatgtcatg
    11941 actaaccaaa atcatggttt gacctgactt agcagcatct gcaatagact tttctacttc
    12001 accaaccaat tctgggtcaa gggctgaagt tggttcgtct aagagcaaaa catctggttt
    12061 catagcaagc gcacgcgcta gggcaacccg ttgcttctgt ccacctgata aatggcgagg
    12121 ataatggttt tcacggtccg aaagcccaac cttagccaac tcttccttgg caatcttagt
    12181 cgcttcttgg tcagataatt tcttgacaac aaccaagcct tctttcacat tatcaagtgc
    12241 tgttcggcgt tcaaacaaat taaactgttg gaaaaccata gacaacttac gacgtagggc
    12301 aaggatttct tcttgagtga ttttagaaaa atcaactgaa aaaccatcaa tctgaataga
    12361 gccactgtca ggtgtttcaa gataattgag actgcgaaga aaggttgatt ttccagctcc
    12421 tgaagaacca atcaaggcta caacttcccc tttttgaata tccaagtcca gatgatccaa
    12481 gacagtctgt cctgaaaagg atttgcttaa atttgaaatc ttaatcatta acgaaggtct
    12541 cctttcacat ctgtttgcac tgtatcaggt gcagaaatag ccatttttct ctcgatgaaa
    12601 cgaccgaggc tttcaattcc gatattgacc acccaataaa caagggcaac ggagatgaag
    12661 cgttcaaaat agcgataatc agctccacct agaatctgag cttgggcaaa gacttccaca
    12721 acacccgcac taaaagctag agatgttccc ttggtcaaac cgatgaggga attaatcaag
    12781 gttggagtag ctaccaccgc tgcattagga ataatcactc gtcgataaac ttgcgctcgg
    12841 gtcataccca gactgcgtgc cgcctcaatc tcaccaggat taactgagag aatggctgca
    12901 cgaatggttt cactagcata agctgcctca ttaaaggcaa aggcgacaat cgcaaaagct
    12961 gcagctggaa tcgcattgat attgagacca gttccccatt gctgattgag ggctttcaaa
    13021 gccaaaggga ttccgtagta ggtcaacatg agttgcacca aaatcggtgt cccttttaag
    13081 aaactaacaa agaaggcctg caagggatat aaaatcttga cacgattgat cttcacaatg
    13141 gcaaaaagaa gcgccaaaac caagccaaaa agggcaccac caattgtcaa cataattgtt
    13201 gttggaagtt gttggacaat tctagggatt ccatcaaaga ccgaacgtag gctaaacagc
    13261 ttgccatccg gaatcaattg catcaagttt tggtaccaat ctgatgctaa aatcgttgta
    13321 acattcataa aaacatcctc ttctgataat gattcattct accatgcttc tgccgtcaat
    13381 gaaattattt gctacggtca gatacagact ttgtctacct actagtttat catactttga
    13441 aacagggaag ttatatattt tatctatcaa agagatagat aaaaactatt tcagtcccag
    13501 ttcttcataa gattttcgat aaccgatttg cttaacagtt ccattttcta ctaaaatagg
    13561 ccgttttaac aacataccgt cacttgctag caactcagcc gcttcttggt ttgacaaact
    13621 tcctacctta tcttttagcc ctaattcacg gtatttgata ccactggtgt tgaaaaattg
    13681 cttcaattca aatcctgagg tttctagcca attcaaaatg acttcttggc taggtgtttc
    13741 ttccacgata tggacggctt tatagtccac acctaattga tttaattctt gttttgcttt
    13801 tttacaagtt gaacatttgg ggtattcgat aaattctaac atgtgcttct ccttctattg
    13861 tttctatctt taaaatctac tccttcatgc tccaagagcc aagctttctt ttccactcct
    13921 gcagcataac ctgtcagacg cttgcctgct cccaacacac gatgacaagg tactaggata
    13981 gaccaaggat tgcgtcccac tgctccacca attgcttgag cagaagccac ttgcaggtct
    14041 tgagcaattt gtccataggt cactgtctga ccataaggaa tgccctgtaa atagtcccaa
    14101 actctctttt caaaattcgt tccgattggc gccaagagca agttggataa atcctgaggc
    14161 ttgcctttaa agtaatcatc taagcaagca ataactgggt ctaaaatagg atgactaaca
    14221 acttcttcta tcgtttcatc tcctagtccc ctctcaaaat gcttctgctc ctgaacccaa
    14281 attccataca aataatggtc atcagctaca agtgatagaa taccaattgg tgaggagtag
    14341 aggattttta catacttctt ttgcattatt tctttaattt ttgataggcc aagcgttcgc
    14401 catctactgg caccttacca acttgtttaa aaccaagttt ttcaaaaata tgttgcataa
    14461 ccttgttttc agcatgcgta tctgagcgaa aatcaagata atcaaaacct tcaatcaagc
    14521 cctctaagaa ggtttgagca actccttttc cctgcacatc tgctgccaca gcaatacggt
    14581 gaaagactag atactctgac tctcccgctt gccagtttcc ctcataaata gcttcatagg
    14641 cctcctctgg actcttggtc acagcagcat aggctagcag ttctccctct tccaaggcta
    14701 cgtaggcttg ccctgagatg atatcatcga taataacatc tgcatttgga tagccatttt
    14761 gccactggtc actaccagca tctgctaaac attttttggc atcctccatc acctgcatga
    14821 tggcatctac ttcatttgga aaagctaaac gaatttccat cttttttcct catttctgac
    14881 tagtttctcc catcatagca taatttaagt atttctacaa gcagttaaaa cttgactttg
    14941 tgtttttgtt attttataat ctagttatca aaactatata aaaaggagtt gaaaatgaaa
    15001 actacctttt cctacccaaa atgggcagaa attccaaaca ttgacctcta tctggaccag
    15061 gttttgctct atgtcgatca ggtctgcgcc cctatctctc ctaataaaga caagggccta
    15121 acagcatcta tggtcaacaa ttatgtgaaa aatggttacc tgacaaagcc tgacaaaaaa
    15181 aaataccaac gccaacagat tgcccgtttg attgctatca caaccctcaa gtctgtattt
    15241 tctattcaag aaatagccca gacacttaat actctacaaa ctcaagcaag ttcagaccaa
    15301 ctctacgatg cttttgtgga ctacatgaac caaggaattg acccagctaa ccctattatc
    15361 caaaccagct gccaaaccgt taaactctat catcaaactc tagacttaat cgatcatact
    15421 caagaggagg taatccaatg aacactagtc ttaaactcag caaacaactc agttttggag
    15481 aggagattgc taatagcgtg acccatgctg tgggtgcagt catcatgctt atcttgctgc
    15541 ctatttcatc catctatagt tatgaagcac acggattttt atcctctatc ggcgtttcca
    15601 ttttcgtcat cagtctcttt ctcatgttcc tatcatccac catttatcac tctatggcct
    15661 atggttcgac ccacaaatat gttttgcgaa tcattgacca ttctatgatt tacgttgcca
    15721 ttgccggctc atacacgccc gttgtcttga ccttgatgaa taactggttt ggctatctga
    15781 ttattgtcat ccaatgggga acgaccatct ttggtattct ctataaaatc tttgctaaaa
    15841 aggtcaatga gaaatttagc cttgctcttt atctgattat gggctggttg gttctggcta
    15901 tcattcctgc cattatcagt caaacgacac ccgttttctg gagtctcatg gtaactggcg
    15961 gactctgtta tacagttgga gctggatttt atgccaagaa aaaaccttat ttccacatga
    16021 tttggcatct ctttatccta gctgcgtccg cacttcaata catcgctatt gtttattaca
    16081 tgtaaaaaag ttgagaaatt caatctcaac ttttttcttt acacatattg ataaagtact
    16141 ggtgcaagcg cacatcatca gtcaattctg gatgaaaaga acttaccaac atattttttt
    16201 cttgggctgc aacaatttga ttgttcactg ttgctagaat ttctacaccc tcaccaacac
    16261 tactgataat cggaccacgg ataaaggtca ttggaatctt gccaactccc ttacattctg
    16321 cttccgtgta gaaacttcct aattggcgcc cataagcatt acgctcgacc accatatcca
    16381 tagttcctag atgactctct ttctgagaag tgatttcctt agccagcaaa attaagcccg
    16441 cacaggtccc aaacactggt aagccagata gaatggcttc tcggatggga agtagcatgt
    16501 tctggtcacg taagagcttg cccatggttg tagactcacc accaggcaaa atcaaacccg
    16561 acaagtcact ctgatcttgc tgaaaatcat ctagatttct gagttctaca ctctcgacac
    16621 ctaattgatc tagcactttt gcatgttctg caaaggcccc ttgcaaggcc aatattccga
    16681 ttttcatcta ttttcctcgt tcagccatga gaatttggat ttcattttca ttaataccaa
    16741 ccatggcttc tcctaaatct tcagagattt gagctaggat ttgaggatta cggaagttag
    16801 tcacagcctt aacaatggca ctcgctcgtt taacaggatc tcctgacttg aaaatacctg
    16861 aaccgacaaa gaccccctct gcccctaatt gcatcattaa cgcagcatct gctggcgttg
    16921 caacacctcc agcagcgaaa tttacaactg gcaattttcc atgttcatga acatattgga
    16981 ccaattctac agggacttgc aaatccttgg cagcaacata aagctcgtcc tcacgtaagt
    17041 tttgaatgcg gcgaatttcc tgattcatca tacgcatatg acgaacagct tggacgatat
    17101 cccctgtccc tggttctcct ttggtacgaa tcatggaagc accttcagcg atacgacgca
    17161 aggcttcacc caaatcctta gcaccacaga caaaaggaac ttggaattct ttcttgtcca
    17221 catggaaacg gtcatcagct ggagatagaa cttcactctc gtcgatataa tcaatttcaa
    17281 tagcctctaa aatctgagct tcaacaaaat gcccgattct gaccttagcc attactggaa
    17341 tactaaccgc ttcttggatt tccttaatca tctttgggtc gctcatgcgg gaaactcctc
    17401 cagctgcacg aatatcagcc ggaattcgtt ccaaggccat cacagctgcc gcaccagcag
    17461 cttctgcgat acgagcctgt tcaggattct gcacatccat aataacacca cccttgagca
    17521 tctgtgccaa gtttttattt agttcataac gattttcagt catttgtttt atcctcatca
    17581 tttgtattgg tagctacctt ttcattttaa gtcagaacag aatgaagcac aagataaaaa
    17641 aactataatt gtatggggac agattggcta aaaactatct gaccttaact taaggccaga
    17701 tagctcattc atttttatct ttcagccgta agggcagcca ttgtgatgta gttgtatggt
    17761 ttattgaagt gtggcaagaa gaagaggtct gtcaatgcca atttatcaat tgtcacatgc
    17821 tcttggatag caagtgagaa catgtggatt cccatgctaa ttgcaatatc atgtgaaacc
    17881 atttgggcac caagaatttc acggctatct ttgtcaaaga caatcttaat tgctacttca
    17941 tggttgtcat gtttcatgaa ttctggtttt tgaagatcgt taaagcctgt ttcagttgcg
    18001 ttgtaaccag cagctttcgc tttttcaaga gtcaaaccag ttgaaaccat gtgaagaccg
    18061 tagattgaga taccatttga accttgaaca ccgattcctt ccaattcatg tccacaagcg
    18121 ttgtaggcac caacgatacc agtgcgaaca gcatttgaag caagagcgat atagcttgta
    18181 tctttacgag cattgtcata aacagtcgca cagtcaccaa cagcgtaaac gcctgggata
    18241 gatgtttctt gtttcttgtc tacaaggaag gcaccgttgc ggaagagttc gatcttacca
    18301 tctgcaaggg ctgtgtttgg acggaaacca actgcaagga taaccatatc cacgtcaaag
    18361 ctttctttgt cagtaatcaa gcgttcaact ttaccgtcac cttcgattgc tttaacagtt
    18421 tgacctagag ccaagcggat gttgtgatct tccaagttct tcgccatcat ttgtgtgaag
    18481 tctttgtcat agtaaccgtt caagacagta tcaacgatat caacaaggac aacttctttt
    18541 ccaagacgtt caaaggcttc agcaagttca acaccgatgt aaccaccacc aacaacggcg
    18601 atacggtcga ggtgttggct cttgtcagaa agtttattga taacttcttc agcattttgg
    18661 tacaatttca cgaattgtac gttttcaaga gttgctttaa attcgcggtt tcctttaaca
    18721 atttcaacac cttcgattgg tggcaagatt ggtgtagaac ctgtagcgaa aatcaatttt
    18781 tcgtatgatt ctttgtgctc ttttccttca acttccgctg taactacttt gttatcatag
    18841 tcgattgaaa gaacaggtga gttcatgtaa actttagcac ctttagcttc caatttttct
    18901 ttatcagaat agaacaagcc ttcagcaccg tcaatttgtt caccaatcca aagagccatt
    18961 ccacatccta ggaaagagat gttagagttt tggtcaaata caacaatttc gttctcattt
    19021 ccaaaattat ccaacatggt attgatacat gctgtaccag cgtggttagc accgactaca
    19081 acgattttac tcataaaaat ttcctgcctt cattctaaat ttaccttact agtataccat
    19141 ttaccgttag cgtttacaag gggggtacta ttatttcagc attttttatc aaaaataatt
    19201 ccccatttat cctgttttca agcctcatga attttatgag catatttctt gactttttcc
    19261 aaattttgtt tgtgaaaatt ctaactttat ggtattataa taacatgaaa atgaaatgta
    19321 agggcttcaa tttagatgat tatttgatat tacaacttat tttctataag agaaaggagt
    19381 tggtagcttg actcttcgtt cacattctga acggctaatg gggactacta tcactatttc
    19441 attagtggat gagcaagccg atatctttct ccaaaaatcc tttgacttgc tcaaagaact
    19501 tgaataccgc ttcaacgcca atagtcaaga atctgagttg atggaaatca attatcaagc
    19561 aggaatagcc cccgtcacgg ttcatccaga cctgtttgag ctgatttcac ttgggttaga
    19621 gcatagccta gcgctctcta gccacctcaa tatcagcatt ggtcccttaa ttcaaacctg
    19681 gcgtatcggt ttttcagatg ccaaggtcgc ccagcctcaa gaaattgaat cggtgctgcc
    19741 tctaatcaat cctcatggta tcgagttaga ttcttctact tctactgtgt ttttaaaaca
    19801 gaaaggaatg aagatcgatc taggttgttt agccaaagga tacagtgcgg ataaggttgc
    19861 ccaatttctt aggaaagagg gggtgacttc tgccttgatc aatctgggag ggaatatcct
    19921 gaccattgga aaaaatcagg caagagggga taacccatgg caaatcggga ttcaagaccc
    19981 agccaatcct aggggaaatc atttaatgac catccctgtt gtcaataaat ctgtcgtgac
    20041 ttcaggcatt tatgaacgtc acctgaccgt cgatggacaa gattaccatc acatttttga
    20101 cagtcaaaca ggatatcctg ttgaaacgga actagcgagt ctaacaatca tctctgataa
    20161 atcagtcgat ggcgaaatct ggacgactcg actctttgga gaaagacctg cttctatcct
    20221 ctggcaagtc gaaagtttgg agggcatcga agtcatcctc atcgataaag aaggccacct
    20281 aagctgttct tcaggaattc ctactctata gagacaactg tttcaatgga attttaaaat
    20341 tgtattatgt aaaaagagaa aggaaatctc atgttaaaac ttattgctat tgttggaaca
    20401 aattcaaaac gttctacaaa ccgtcaattg cttcaataca tgcaaaaaca ctttgctgac
    20461 aaagctgaaa ttgagcttgt tgaaatcaag gccattcctg tcttcaacaa accagctgac
    20521 aagcaagtac ctgctgaaat attggaaatt gctgctaaaa tcgaagagac agatggcgtt
    20581 attatcggta ctcctgagta tgatcactct attccagctg ttttgatgag cgctcttgct
    20641 tggttgtctt atggtattta cccacttttg aacaaaccaa tcatgattac aggtgcttct
    20701 tacggtacgc ttggttcatc tcgtgcccaa ttgcaacttc gtcaaatctt gaatgctcct
    20761 gaaatcaagg caaatgttct tccagatgaa ttcttgctct cacactctct tcaagcattt
    20821 aacccaagtg gcgacttggt tgaccttgat gttatcaaga aattggatgc catctttgat
    20881 gacttccgta tctttgtaaa aatcacagaa aaattacgta atgcacaaga attacttcgc
    20941 aaagatgctg aagactttga ctgggaaaat ttgtaagata ggagaccaaa aagaatgaaa
    21001 tttgttggac ttgttggatc aaactacgat caatcatata accgtaagct cttggaattt
    21061 atccgtcgct acttcaaact caaatttgaa ttagaagttc ttgaaattga cgaagttcca
    21121 atgtttaacc aagatgaaaa atgggatgaa agtttccaat tacgttattt atataacaaa
    21181 attactcgtg cagatggtgt tatcattgct actcctgagc ataaccacac tatctcagtt
    21241 tcactcaaat ctgtacttga atggctttca tacgaagttc atccatttga aaacaagcct
    21301 gttatgattg tgggtgcatc atactatgac caaggaacat cacgtgctca agttcacctt
    21361 cgtaaaatcc ttgatgctcc aggtgttaat gcctacacgc ttccaggtaa cgaattcctt
    21421 cttggtaaag ctaaggaagc ttttgataac aacggaaata tcaccaacga aggcactgtt
    21481 aaattccttg aaacttgctt agataacttt gttaaatacg taggagtcgt ttcgaaattg
    21541 aaaaaaccaa aaccaatcga atcagaagac ttggattgtg gaaaaccaat cgctacaacc
    21601 atcacagaag ttgaccctga cgatccagaa tgggtagaaa aagttgcagc aatcactggt
    21661 gctgtttctg gtgataccta tgtcaaattg gaccacggta tcctaacagt taaccaaatt
    21721 gatatgttct tgaaagctat gccatttgaa ttgacatacg ctgacgacaa caaccaattc
    21781 ctctactaca acaacgctca ccaagatcca gacactatgt tcgctaaacg tgtaccacct
    21841 caatcaggta gccgtatgtc gactgttcat ggttctcttc caccagcacg tatgaagaac
    21901 gtagagtggg ttatcggaac acttcgcaac ggaaaccaag aatacgtccg tacgatcgtt
    21961 ccaggttctc ctgcaggtgt tatcaacact cacaactacc aagcaatgta ctatcctgat
    22021 ggatcatacg ctggtatcaa tgaaatcgtc tttaacttcc aaccatggct tgactggtac
    22081 ctaaaagaga ctggtcaacg tttggtgggt ggtagcggac catttgctcc tgctgccgga
    22141 ggtcatggaa acgccgatgc tacttctggc gcttctgatt caggggatgc tggaggccac
    22201 ggtggtgacg cagatgctac agccggtgca agttactaat gatagttttt aggaaccatt
    22261 atggttcctt ttttagcgaa aaaagactag caaacacaaa ctgctagtct ctttgttatc
    22321 gtttcatcta tctttgttaa aagaaaaata catattatga atttgggtca tcaagactac
    22381 ggccatgtaa tcctttttca cgttgtactt ggcgtagttt ttctggtgta acatcgtttc
    22441 ctttttcgtc cacaattttg attccttcaa tgtgatgacg aacagcgcga cgataacctt
    22501 cgatgtactc ctcacgtagt ttggcttgtt ccactttttc ttctggtgtt aagccttctg
    22561 tttttttctt tttagcaagc tcattgatac gagcaatttt tttcggatcc atttcttctc
    22621 ctctgtaata agataaagtc cgtttatcaa attttattta gtgttaattt ggttaaaaca
    22681 agcaaactta gctgctttct tggttagttg tgacaagatt gccaaacgat tttgacggac
    22741 agcctgatct tcagccatta ccatagtatt ttcaaagaaa gcatcaatga ctgggctaag
    22801 cgcaaaaagt tgtttcaatt gctgacttgc aggtcctgat aaaatgagtg tttctactgc
    22861 ttctgccaaa gctttttctt ggtcattctc aaatagtgct gaatcaaccg tagcaacccc
    22921 ttctgccttc tcagccaggt taaaggcacg agaaagtgat tcaacagatg gtttaaaatc
    22981 ttcttccttg cttacttcta cgagagcact tgctgcttcc aacatatctg ccacaacaaa
    23041 gtttgaacct gcaagaactg cttccttgat atcttttgga gtagagccca tcatcttatc
    23101 aacacgagcc ttgataaagt ccataacctc tgctttattt tcataagtca aactgtcaaa
    23161 tttcaatgca taaaggctat caatcagctc atccatagca atgtgccaac caaaggcatc
    23221 caagatacga accacacctt gagttgcacg acgaagggca taagggtcat tagaacctga
    23281 tggaatcaat cctactgaga agaaactcaa aatcgtatcc aatttgtctg caatggctag
    23341 aactgcaccg accttgctct ctggaagttc tccttcagct gatgtaggca tgtagtgttc
    23401 acgaatagca gctgccaccg ctggagtttc accagcaaga agggtgtatt tttcacccat
    23461 aattccttgg agttcgtcaa attcaccaac catacctgtc aacaagtcaa acttgtaaat
    23521 ggctgctgca cgagcaaggt caactgtttc atccactgac aaaccagctt tttctgccaa
    23581 aagtacagtg atttgacccg tacgaatcat gtgttcacga agggaaccaa tcttctcatg
    23641 gaaggtaaca ttgtttaatt tttcaacaag atctgaaatc accaattttt ggtcttcacg
    23701 ccagaagaat tctccgtctt ccaagcgggc taccaagact ttttcatttc ctttaatgac
    23761 atttttcaaa cgctctgcgt ttccgttacg aacagaaatg aagtttggca agagttttcc
    23821 atcttgatca cgaacaacaa agtaacgctg gtgttccttc atagaagtca ccaagacttc
    23881 ttctggaact tcaaggtatt tagcatcaaa acttcccatg aaggcagttg ggtattcaac
    23941 caaattcaag acttcattca gcaaatccgc atcaatttcg atacgtacac catgttttgc
    24001 ctcaatttcc ttgatttggt caacaatcat ttgctcacgt tcacatggat ctgcgattac
    24061 aaactgctta cgaaggtctt cttcatagct caatgctgac tgaattttgg tttctttccc
    24121 caagaaacga tggccacggc tcacacgact tcccttgata tcaaggaaat ccaagtcaaa
    24181 ctcttgctca tccaagagaa cagttaaagt gtgaacaggg cggatgtatt caaagctatt
    24241 tccagcccag tgcatgctga cagggaaagt caatgacttc aagacatcta caacaccagg
    24301 aacaatggct tcaactgatt ggccaacttc ttccttagtg acatagacat attcttcacc
    24361 cttaatttca cggaattcga tatcttcaac agtcaaacct ttcccacgga caaatccttg
    24421 agctgctttg gtgaagtttc catcactatc caaggcaatt ttctttgctg gtcccttgaa
    24481 atcttctgtc aaatcagact gtttgtctga taaaccagtc acacgaacag ccaaacgacg
    24541 tggtgttgag aaggtttgaa tggcttcaaa agacaggcgg ttttccttga ggaaggctgc
    24601 cattttttcg cctagttgtt tttcacttgg tgtgacaaca taggctggta attcttcaag
    24661 accgagttct actaataagt tttttgtcat gttttttgtc atgttttttc tccgaaaagt
    24721 atctttttat tttccagttt gccttatgtg attggcacgc aagcaaccaa cttcgttgtt
    24781 tcattgctaa aattggagcc aaaagtctcc aattttgcct agtatcctta gtttcactaa
    24841 ggataccttc atcactgcgg caactggctc agggctcact ctgttcgccc attttcgtaa
    24901 tttgtcactc tctttattct gcgtcttctg ctaggagttt agctcttgtt tcttcatcca
    24961 aaagtgggta gcctaggcgt ttgcgttctg cgacaaaggt tttggctacg acacgggcca
    25021 agttacggat acgagcgata tagcctgcac gctctgttac agatacggca ccacgcgcgt
    25081 caagcagatt aaaggtatgt gaacatttga gaacatagtc ataggcaggg tgtaccaagc
    25141 cttcttctaa tgcacgacca gcttcttttt caaacttatc aaaattttca agcaacattt
    25201 cttggtccga aatttcaaat gaatattttg agtgctcata ctcaggctgg ataaagattt
    25261 ctccgtattt tacaccatca gcccactcga tatcatagac agagtctact tcttgaatgt
    25321 aagaagccaa gcgctccaaa ccataggtaa cttccgcagt cacagggcta gttgccaatc
    25381 caccgacttg ttggaaataa gtgaactgag tgatttccat tccgtcaagc caaacttccc
    25441 aaccaagacc agctgaacca gttgatgggt tttcccagtt gtcctcaaca aaacgaatat
    25501 cgtgctccaa aggattgatt cccaattttt ccaaagactc aaggtaaagt tcttggatat
    25561 ttgatggaga aggcttcatg accacctgga attggtggtg ttggtagaga cggttagggt
    25621 tttccccata acgaccgtca gcaggacgac gtgatggctc tacataagct gcattccatg
    25681 gctcaggtcc gatagcacga aggaaagtgt aaggactcat tgttcccgca cctttttcat
    25741 tgtcataagc ctgcataagc atacaacctt ggtcattcca aaatcgttgc aaagtcaaaa
    25801 taatttcttg aaatgttaat ttcttagaca ttgaatactc cttaataaaa aataatttct
    25861 tgcgacacga gtctacctcg tcgattatac gaggcaagac gagttagtac tgcgtctagc
    25921 tcagcaccct agtgctgagc gtggggcagt ccgactgtaa ggaggtctct gccactgatg
    25981 cagtgaaatg tcaatttctt agacattgtt tactccttta gtttttatat ttctttttca
    26041 attaatttct gctgaacaaa ccaatctaac aagggaaaag ttttttctgt atttgcccat
    26101 aaatgataag aatctaagac cgcttgtaca ctacctaaat tttctaccaa cttatctact
    26161 gtcaaaaagc tgcgccagta ttcataaaaa atacttgcat agttcttatc ataagtcgaa
    26221 gaaccaaaat cattcaatga atgccaacca tacttcttct gaaaaagttc tacgagagat
    26281 tgattacaaa ttttttccgc ttgaaattcc tcttctgtca agaaatactt gcgactaata
    26341 tattcaacca tcccctcttc gaaccagata taagagtcat aaccatcaaa atcatctaaa
    26401 aaatgctccg accaatgagc taactcatgt cctataatct gtaagaggaa attttcagat
    26461 aaagaatgat agtgactttc tattgcttga gtttgctgag aacactcgta gtccatcaat
    26521 tgatacaaat acaactcttt ccaaacagct aaatcaggcg ccataaccat tcgtctatta
    26581 tttgtatagg ctggaacagc gctttcccta ataatctgtg tagcagcatt aaaatctgac
    26641 caaataacgg cttgcggtaa atcacagact gcaagttcat tctttaaaaa agattgataa
    26701 tctttcaact tttcagtatt tcttactaca aaatcacgaa atgtagctag ttgactatcg
    26761 tcttttacaa gataaaggtt gtccacggct ctcctttctt tcacacaata gactgaataa
    26821 gcaaaagaac cacatctgac aatcctaggt tgatttaacc taggggcgtc agaaacgcgg
    26881 ttccacccta atttattact tcattgtttt tgaaaatact acagaaagcg ccagcccttt
    26941 attttgccct acttggctcc cactatccca agctcgcttg aagaacgcca taagactttc
    27001 tttcctgctg actattatat caaaaattag aataatgtac aattcttttt atgattttct
    27061 agaaatccac atcatcaact cgtggagcac ccgattgaac agcaatcgtt tttaaggttt
    27121 ctctctcctc atgactcagt tcaattccaa agcaatcaag attagcttga atacgagagg
    27181 ttgtgataga ttttggaagt ggtaaaaatc cttctgccaa gctccaggcc aaggctatct
    27241 gagcaatcga ttttccgtga tttgctgcga tttcttgcac ttgcttgcta tcaaatagtt
    27301 ctccctgacc aaaaggcccc caagcttcca ataaaattcc cttttcacga cagtaagcta
    27361 cgacttgatc ttgatacaca cctggcgcca agcgaacttg attgaccgca ggaacgatag
    27421 ttgcagtttc aagcaaggca tccaaatgat ggggaagaaa attgctaacg ccgatagcac
    27481 ggattttccc ttcttgatag aggtcttcca tcgctctcca aacttccgca ttgcgagttt
    27541 tccatgcgtc attttctctg agcggttttg ggttcggcca atgaatcaaa tacaaatcca
    27601 aataatccaa gcccagtttt tctatagatt tttccaaagc ttgacgagtt tgctcatagg
    27661 tttgctgact attccaaagc ttggtagtta cgaacatttc ttcacgtgga actccgctat
    27721 ctttgattgc ttgaccaaca ctttcttcat tctgataaat cgccgccgta tcaatatgac
    27781 gataaccagc cttcaaggct tctaacactg cacgataggc ttcttctcca tccttagcct
    27841 taaaagttcc aaatcccaat actggaattt ctactccatt atttaattga taggtattca
    27901 tatgcttctc cttctatttt attcatcaat tatagcataa aacatttttt aagtagtact
    27961 atcttctgta aaaaataagt ctgtcaaata tctaacagac ctattttttc ttgcttattc
    28021 atcacgacta tagtacagct catgagcttt taggcgagta ttgagcatct ctggtatggt
    28081 cacaaaggta taaccttgat ttttcaaata ctcaatgacc cttggcaagg cattgactgt
    28141 cggactgtga atatcatgca tcaaaacgat agagccgtta gctacttgat gctgaatttc
    28201 tgtcaaaata gatgcttcat ttttactctt ccagtccaga ctatccacat cccacatgat
    28261 aaagctcaaa tccaagctat tgcgaatatc atctgtaata gcaccataag gtggacgcat
    28321 gagtttagaa ctagaaccca gcactttagt tagcacatcc tcagtatcag taatctgctt
    28381 tttagcttca tcaagagaga gttgcgagag aatcggatgg ctccaactat ggtttccaac
    28441 aacatgacct tcagatttta tcctcttcac caagtcctca ttcccagaaa catttttccc
    28501 aagcacaaag aaagtcgctt taatatcata tttagctagg gtctctaata cctgcggggt
    28561 cgttgctgga tttggaccat catcaaaggt tagagcgaca actttttgat atttcttatc
    28621 aaagtaagat tggtacaagg ccgcatcttt ttcgagtaag tacgaagatt ggataacatc
    28681 aaagaaagca gatactggca aggctatctc ttctaaattt tcaaccacag gacttggata
    28741 aaggataatc tgactatcct tgtaatcaaa attccatgca gacaagtctt ggtcagagaa
    28801 gttttttaca atctgctcac tctggtcttg ctctattttt ttatcctcta tgaaggaggt
    28861 caactctttt atcagctgtt ccttagcctt actagcatct gaaaacagtt ggtcaagtgt
    28921 aaaaggttgc ccatcttctg ttaagtgaac ctttcctaga ctggtctttt cagtctcttc
    28981 aatcttaaaa gcaactaaat catagatttg tttggtcaca ttacgattaa cgactccctt
    29041 taaacctgac tcttcttgct ctgtatagta gaaaacaaga ttgtccttac tttctagctt
    29101 gtccttaaca tcttgattta tcagctccct aacagaggaa atcactttct ccccttggag
    29161 aggataatag gcaatcactt cggcttgccc ctgacgaaaa tgctccttct gatttccctc
    29221 actcaattga tcatctttct cttttttgag cgattcaatc ttttgctcaa aacttttttg
    29281 ctggtagatc ttaaaagcaa taaatccgcc taataggcaa atagaaattg ctaagatacc
    29341 aatcaaagcc aataatacat gtctcgtttt cccgtgtctg ccacgtccta gtctactttt
    29401 attcatattt atatcataac aaatttgagc aataatttca atgatacaat ttggcaatcc
    29461 acaattcctc tagcaagcca aagcatctta catcaactcc aacatccgta tctgtagaga
    29521 ttatgtagtt ttctatctat ggaatttcta gtagattgaa gctagaatag tagacctata
    29581 cttctaaaac attgttagaa atcgatttga ctgtcctgat cgatttgtcc tgttctcatt
    29641 tcattttact ataaaactat gaaaagctag gtcatctgag aagtaattac tatcgacaat
    29701 tgcgatagcg tatactggtg cgatgtgttt gtagctctgg tgggtatcac cttcacgttg
    29761 gcaaattttt tctaggtttt gattaacctg actgcacaga taagcccata ggcgattgat
    29821 gaaaaaattc tgatgatgaa cctgaatttc gatgataact tggattccat tatctaactc
    29881 cgccaagacg tctatactag tatagaaatc ctgcgctgag tagggcatgg aaggcaagac
    29941 gtgaatgtta cttccctcca aaatcgtcac attttttgct ggcaagtcca gcatatcgcg
    30001 gataaattga caaatcatta gttgggctga tacccggatg tctgagaatc ctccttttcc
    30061 tccttctatt atagcacatt tttaaatcta ggtttgctag attctatgct tctatctatt
    30121 tattcggaaa agaaagcttt tcttcagaag aaagctaata gcttatttga aattttctcc
    30181 tctctgttgg atagtcccgt ctatctatgt tataatgaaa gaaggattta aaatcggaaa
    30241 aggagtattt atgctaaaat taggtgtcat cggaactggc gctatcagcc atcatttcat
    30301 agaagcatcc cataccagtg gagaatacca actggtcgca atctattcta gaaaactaga
    30361 aactgcagca acctttgctt ctcgctatca aaatatccaa ctattcgatc aattagaagt
    30421 cttcttcaaa tcttcttttg atttagtcta tatcgccagt ccaaactcct tacattttgc
    30481 tcaggcaaaa gctgccttgt ctgctggtaa acatgttatt cttgaaaagc cagctgtcac
    30541 tcaaccacaa gaatggtttg atttgattca aacagctgaa aaaaataact gttttatctt
    30601 tgaagcagct cgtaattatc acgagaaagc ctttactact atcaaaaact ttttagcaga
    30661 taagcaagtg ttaggagcag atttcaacta tgccaaatac tcttccaaga tgcctgactt
    30721 gttggctgga caaacaccaa atgtcttttc agaccgtttt gctggtggag ccctcatgga
    30781 tttggggatt tatcccctct atgctgctgt tcgtcttttt ggaaaagcca atgacgcgac
    30841 ttaccatgct caacagcttg acaatagcat tgacctaaat ggagatggta tcctcttcta
    30901 cccagactat caagttcaca tcaaggctgg aaaaaacatc acttccaatc ttccttgcga
    30961 gatttataca acagatggaa ccttgactct caacacgatt gagcatattc gctcagctat
    31021 ttttaccgac caccaaggaa atcaagtcca gcttcctatc caacaggctc ctcatacgat
    31081 gactgaggaa gtcgctgcat ttgcacacat gatccagcaa ccagatctga atctctacca
    31141 aacttggctg tatgatgcag gctctgttca tgagctacta tataccatgc gccagactgc
    31201 tggcattaga tttgaggcag aaaaatgaaa accaaactac cgactgaatg gcaagaactg
    31261 agtgaccaac tcggtttcca agaattcacc cccattcaaa ctcaactatt tgagcccctt
    31321 cttgctggag aaaacctcct aggagtgagc aaaaccggaa ctggtaagac cctagcgtat
    31381 ctcctaccaa gtcttctcag actacaaaag aaaaaagccc aacaactctt gattctagca
    31441 ccaaatacag aacttgctgg acagattttt gatgtatgta aaacgtgggc agaagctatc
    31501 ggattgactg ctcaactctt cctttcaggt tcaagtcaga aacgacaaat tgaacgtctt
    31561 aaaaaggggc cagaaattct gattggaact cctggccgta tctttgaact cattaaactt
    31621 aaaaaaatca agatgatgaa tgtggaaacc atcatcctgg atgaatttga ccaattacta
    31681 gatgattctc agattcactt tgtagaaaaa atcactcact acgcacctcg tgaccaccaa
    31741 ctgatctaca tgagtgccac gaccaagttt gaccaagaaa agattgtgcc gaatacacgc
    31801 actattgatc tctctgatca aaaattggac aatatccagc atttctacat gcaggtagac
    31861 caacgtcatc gagtggatat gctacgaaaa ctggctcatg tagaggattt ccgtggtcta
    31921 gtcttcttca atagcctgtc agaccttggg aatgccgagg aaaaactaca gtatcgtgat
    31981 atattggctg tttccctcgc tagtgatgtt aatgttaaat ttagaaaagt catcttagaa
    32041 aagtttaaag ataaccaact aaccctgctt cttgcaactg accttttggc tcgtggaatt
    32101 gatatcgata gcctagaatg tgtcgtaaac tttgatattc ctagagatag cgaaacctac
    32161 acacaccgtg ctggccgtac tggccgtatg ggcaaggaag gatatgttat tactctcgtc
    32221 actcatccag aagaaatcaa aaaacttaaa aagtttgcaa gtatccgaga aattgtccta
    32281 aaaaaccaag aactctatat caaataaagc cccattgctc tatacacatc cagtgtatgg
    32341 agctttttta taagcaattc aattttatac tcatctgctt tcaaaaagca ttctagtcca
    32401 tctccgatta acgatggact ttatcacctc cttctccagt ccttgtatga catcttggag
    32461 ttgattcatg acatcttcca aagttcgaaa ggctttattc ttaaatccac gtttacgaat
    32521 ctctttccac acttgttcaa tggggttcat ctctggtgtg tacggaggaa taaatgcaaa
    32581 gccaatatta gtcggaatct ttaaggtact tgatttatgc catatagcat tgtctataac
    32641 gagtaaaaaa taatcatatg gataagcttg tgaaagctct tctaaaaaga cgttcatcca
    32701 ctcagtatta catccaccag ctattaagaa aactgatgcg cctgtatggg catcaacagc
    32761 tccataacaa tagcgaaatt ctcgtatata gtgactatgg atatgtggac ctactcctat
    32821 tggagcccaa caagatccca gtttactgat tctaccgaaa ccagcctcat cttggtacat
    32881 caagcgaac
//
LOCUS       DAVAGB010000022        32443 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVAGB010000022 DAVAGB010000000
VERSION     DAVAGB010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32443
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.022"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(345..1034)
                     /gene="rplA"
                     /locus_tag="VQO19_001134"
     CDS             complement(345..1034)
                     /gene="rplA"
                     /locus_tag="VQO19_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HET1349414.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKVKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1242..1667)
                     /gene="rplK"
                     /locus_tag="VQO19_001135"
     CDS             complement(1242..1667)
                     /gene="rplK"
                     /locus_tag="VQO19_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HET1349415.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(1790..2506)
                     /locus_tag="VQO19_001136"
     CDS             complement(1790..2506)
                     /locus_tag="VQO19_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HET1349416.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKTKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVSNKGSYYSIQGKYDEIILANKRYPLSKDYNPGENPTAKAELLKLI
                     AAMQAEGYPISDQYSGFRSYETQAKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     LIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(2524..2985)
                     /locus_tag="VQO19_001137"
     CDS             complement(2524..2985)
                     /locus_tag="VQO19_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET1349417.1"
                     /translation="MCLICQRIELIKAGQNPYFVKELETGYVVIGDYQYFKGYTLFLA
                     KDHVTELHHMETSVKLRFLEEMSLVQEAVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     AGDMKSHGLNGRGPVWWVPWEEMAAEDCQVQSPELEEMIKILSHELEKYLA"
     gene            complement(2987..4024)
                     /locus_tag="VQO19_001138"
     CDS             complement(2987..4024)
                     /locus_tag="VQO19_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HET1349418.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNISAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVIATERM
                     VDAYLKSEAVS"
     gene            complement(4122..5447)
                     /gene="brnQ"
                     /locus_tag="VQO19_001139"
     CDS             complement(4122..5447)
                     /gene="brnQ"
                     /locus_tag="VQO19_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HET1349419.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRVLTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5618..5710)
                     /locus_tag="VQO19_001140"
     CDS             complement(5618..5710)
                     /locus_tag="VQO19_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET1349420.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(5753..5905)
                     /locus_tag="VQO19_001141"
     CDS             complement(5753..5905)
                     /locus_tag="VQO19_001141"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET1349421.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(6065..6643)
                     /locus_tag="VQO19_001142"
     CDS             complement(6065..6643)
                     /locus_tag="VQO19_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HET1349422.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(6697..8097)
                     /gene="pepV"
                     /locus_tag="VQO19_001143"
     CDS             complement(6697..8097)
                     /gene="pepV"
                     /locus_tag="VQO19_001143"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HET1349423.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGFKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8110..8715)
                     /locus_tag="VQO19_001144"
     CDS             complement(8110..8715)
                     /locus_tag="VQO19_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HET1349424.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            8886..9686
                     /locus_tag="VQO19_001145"
     CDS             8886..9686
                     /locus_tag="VQO19_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET1349425.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(9870..10703)
                     /locus_tag="VQO19_001146"
                     /pseudo
     CDS             complement(9870..10703)
                     /locus_tag="VQO19_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
     gene            complement(10693..12540)
                     /gene="uvrC"
                     /locus_tag="VQO19_001147"
     CDS             complement(10693..12540)
                     /gene="uvrC"
                     /locus_tag="VQO19_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HET1349426.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQTKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(12580..13281)
                     /locus_tag="VQO19_001148"
     CDS             complement(12580..13281)
                     /locus_tag="VQO19_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HET1349427.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWPQVSARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13360..14592)
                     /gene="murN"
                     /locus_tag="VQO19_001149"
     CDS             complement(13360..14592)
                     /gene="murN"
                     /locus_tag="VQO19_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HET1349428.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLKSIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14597..15817)
                     /gene="murM"
                     /locus_tag="VQO19_001150"
     CDS             complement(14597..15817)
                     /gene="murM"
                     /locus_tag="VQO19_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HET1349429.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRISKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(15929..16708)
                     /locus_tag="VQO19_001151"
     CDS             complement(15929..16708)
                     /locus_tag="VQO19_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET1349430.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQDFSPESQNLG
                     TPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(16777..18438)
                     /locus_tag="VQO19_001152"
     CDS             complement(16777..18438)
                     /locus_tag="VQO19_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET1349431.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18613..20835)
                     /gene="recJ"
                     /locus_tag="VQO19_001153"
     CDS             complement(18613..20835)
                     /gene="recJ"
                     /locus_tag="VQO19_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HET1349432.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIGANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYRFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21112..21870
                     /locus_tag="VQO19_001154"
     CDS             21112..21870
                     /locus_tag="VQO19_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET1349433.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYTHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDMTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            21881..22674
                     /locus_tag="VQO19_001155"
                     /pseudo
     CDS             21881..22674
                     /locus_tag="VQO19_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
     gene            22687..23364
                     /locus_tag="VQO19_001156"
     CDS             22687..23364
                     /locus_tag="VQO19_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET1349434.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQV
                     NKKAYSL"
     gene            23374..24033
                     /locus_tag="VQO19_001157"
     CDS             23374..24033
                     /locus_tag="VQO19_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET1349435.1"
                     /translation="MESILEILTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISNLSHMLAKRWQQAA
                     E"
     gene            24177..25367
                     /locus_tag="VQO19_001158"
     CDS             24177..25367
                     /locus_tag="VQO19_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HET1349436.1"
                     /translation="MKSIKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(25688..26569)
                     /locus_tag="VQO19_001159"
     CDS             complement(25688..26569)
                     /locus_tag="VQO19_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HET1349437.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(26710..28038)
                     /gene="vncS"
                     /locus_tag="VQO19_001160"
     CDS             complement(26710..28038)
                     /gene="vncS"
                     /locus_tag="VQO19_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HET1349438.1"
                     /translation="MKRTGLFTKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTKNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(28035..28691)
                     /gene="vncR"
                     /locus_tag="VQO19_001161"
     CDS             complement(28035..28691)
                     /gene="vncR"
                     /locus_tag="VQO19_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HET1349439.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCIFTVRNVGYKLERK
                     "
     gene            complement(28740..28823)
                     /gene="pep27"
                     /locus_tag="VQO19_001162"
     CDS             complement(28740..28823)
                     /gene="pep27"
                     /locus_tag="VQO19_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HET1349440.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(29003..30382)
                     /gene="vex3"
                     /locus_tag="VQO19_001163"
     CDS             complement(29003..30382)
                     /gene="vex3"
                     /locus_tag="VQO19_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HET1349441.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30434..31081)
                     /gene="vex2"
                     /locus_tag="VQO19_001164"
     CDS             complement(30434..31081)
                     /gene="vex2"
                     /locus_tag="VQO19_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HET1349442.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31094..32371)
                     /locus_tag="VQO19_001165"
     CDS             complement(31094..32371)
                     /locus_tag="VQO19_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET1349443.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQVSLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9173 a         7432 c         6040 g         9798 t
ORIGIN      
        1 tacacctcta cttctaaaac attgttagaa atcgatttga ctgtcctgaa cgattcgtcc
       61 tattcttatt tcattttatt ataattgata gtggtcgccc cagccagata ccttatccgc
      121 tatataggcc ttattatcac gttcctgttc gtagagccac gatttcgcta tcccttcctc
      181 tgacgattct tatttccagc gtcagacttg ggaatcgcta ttgggttcac cggtagtagg
      241 tgcccaccga ggacttacac ctcagatata cgacatgccc gtcgtacatc aaaaaaagtt
      301 gagacatagt gtcttcaact tttttacatt actttaacta ctgattaaag tgagtttacg
      361 tcaactttga taccaacacc ttgagtagtt gtgatagtca agtttgttac gtaagttcct
      421 ttagctgtag ctggttttac tttttggatt gtttcgttga aagctttaaa gttttcaacc
      481 aatttttcag cttcaaatga tactttaccg atgattgctt gaacgttacc tgcacggtca
      541 gcacggtaag tgattttacc acctttagac tcttcaactg ctttagcaac atccattgtt
      601 acagtaccag ttttagggtt tggcatcaag ttacgtggtc caaggacacg tccaagacgt
      661 ccaacaagag ccatcatatc aggtgtagcg ataactacgt cgaagtccaa ccaaccgtcg
      721 ttgattttag caacaaggtc atcttcacca acaaagtctg caccagcagc ttttgcttct
      781 tcagcttttg caccacgtgc gaaaacaaga acacgtgaag ttttaccagt accgtttggc
      841 aataccattg ctccacggat ttgttggtca gcttttttaa cgtcgatgtt caagttgtaa
      901 gcaacttcta cagttgcatc aaattttgca aagttagttt cttttgcaag tgctacagct
      961 tcttctacac tgtatgcttt tgtgctgtcg attttctcaa gagcagcacg aagttgtttg
     1021 ctttttttag ccattttcta ttctccttgt aagtggttca atcgattttc atctcccacg
     1081 tcacttctcg aaatgatgaa gtcttgcggg ttttcagtct actatttttc tcttcctacg
     1141 gccttaagct cccttgctgt atccaagtac aagcctcagt cacttgccta gtatgaaaag
     1201 caactaatag actgctgtga gattttctac tgtgttattg attagtcaac aacagtgaat
     1261 cccatagaac gagcagtacc ttcgatcata cgcattgcag actctacgtt tgcagcgttc
     1321 aaatctggca tcttagtttc tgcaatttct tgtacttgtg cacgagtaac tgtagcaact
     1381 ttagttttat taggtgtacc tgatcctttt tcaacacctg cagctttttt caaaagaaca
     1441 gcagctggtg gtgttttcgt aacgaaagta aatgatttat cttcgtaaac tgagataaca
     1501 actggaatga tcataccagc ttggtcagct gtacgagcgt tgaactcttt tgtgaatccc
     1561 atgatgttga taccagcttg accaagagca ggtccaaccg gtggagctgg tgtagcttta
     1621 ccagcaggga tttgcaattt tacaagtttt tcgacttttt tagccatttt taaatcctcc
     1681 tttgtggttt tggcggtaat tagagatttt tacctcccac aagtatgctt tacacatacc
     1741 tttccattat acactattta tctaaaaatg caagagaaaa ctttcatttt taatcgacat
     1801 aatcgccgcc ttcaaagcca tagtactctt ccaaactgag accacttgca gcaatttctt
     1861 tggcttcttt tccaacgtag cggagatgcc attcttctgc catgtagcca gtctcctttt
     1921 ccttgccttt aagatagcga acaacaaagc catagtcagc cgcatggtcc aagagccact
     1981 gggctgcctt ttcttcagta actaaatccc catctgtccc aatcaaatca aaagcaagac
     2041 ccgtctggtg ttcactgtaa cctgggcgtg ctgagtagcg atctgctgct tccttaccat
     2101 cttgattgac atagtcttgg tagagcttag cctgagtttc ataactccta aacccactgt
     2161 attggtcact gattggatag ccctcagcct gcatagctgc gattagtttg agcaactctg
     2221 ccttggctgt tggattttct cctggattgt aatcttttga caaaggataa cgtttattag
     2281 ctaggataat ctcatcgtat ttcccttgga tactataata gctcccttta ttgctaactt
     2341 ctgccttttt ctgactagaa gcttgagatt tgctacctac agttccttcc ggttgactgc
     2401 tttgctccgt tttttgagtg ttttcttcaa ctttggtttt ttcttgcgaa caagctgcaa
     2461 gggtcaatgc tagtaaacca gataaaatga catatctttt tttcatttct ttcttcctct
     2521 ctcttaggcc aaatacttct ccaattcatg agataagatt ttaatcatct cttccagctc
     2581 tggcgattgt acttggcaat cttctgccgc catttcttcc cagggcaccc accagactgg
     2641 gccacggcca ttcaaaccgt gactcttcat atcacctgct cttcggggaa aaagatgcca
     2701 atgagcgtgg gcatcgccat ttcctaggag ttcaatattc atcttttcag cctcaaatgc
     2761 tttggcgact gcttcttgga ctaaactcat ttcctctaaa aagcgaagtt ttacagaagt
     2821 ttccatatga tggagttctg tgacatgatc ttttgctaaa aataaggtat agcccttaaa
     2881 gtattggtag tcaccaataa caacatagcc tgtttctagt tcttttacaa agtagggatt
     2941 ttgcccagct ttaatgagtt cgattctctg acagattaag cacattctat gataccgcct
     3001 cgctcttaag ataagcatca accatacgct cagtcgctat tactgaatcg atgtgggtgc
     3061 gctcataaga gtgactggac tcaataccag ctccaagaag tgcatgcttg acctctgcac
     3121 ctgctgacat cgctgctgaa gcgtccgatc cgtaaaatgg atagatgtcg agcttaaatg
     3181 gaatatcttg ctctttagcc aaggcaacca aatgttgacg gaagtcatag tgataagggc
     3241 ctgaagcatc cttgacacag atggacactg tgtactcatc tgtttgctgg tcatccccca
     3301 tagctcccat atccacagct agatattcga ctacctgagc agagatatta gagttggcac
     3361 cgtggcctac ttcttcaaag actgaaaagg caaaatgagt tgttactggc aattcaatct
     3421 tctctttctt ataaatacga agcaggttga gcaaaatcgc tgcgctgacc ttatcatcca
     3481 aatgacgaga cttgataaaa cctgtatcag tcacaacagt tcgtggatcg aagctgataa
     3541 aatcaccgac ctcaatccca agagcacgag tttctttttc attgcttact tttacatcca
     3601 aacgcacttc catattgtcc tgcgtgcgtt ctgcagttcc tgcatccttg tagacatggc
     3661 aagaagtttg gtggatgagg atggttcctg ataccttttg acctgtgcta gccacatgaa
     3721 cggtacagtt ttcaccttca atcatgttcc aaggaaaacc accgatacgg tccaatttaa
     3781 gacgaccatc tggtttgaca gcacgaacaa tagcacccag cgtatccaca tgggcagtca
     3841 catagcgatg ttgctcatca ttttgacctt tgatggtcac attgacacca cccttagctg
     3901 tgcgaactgg ctggtaacca aaaccttcta gagtcttgac taaataattc gaaatttcac
     3961 gagtgaagcc cgttggcgat gcgatggctg tcagttcttt gatatattct actgtttgat
     4021 tcatttcttc acctctttcg ctacctatta taacacattt atcatcggat aaaaaaagaa
     4081 aatcactcct gtagacttgg ctacaaaagt gatttaagtg attattccat ttcaaaaaca
     4141 tcgctttctt gcttgtttgg tagaaccaat gagagcaaga ttccaacaat ggctggcacc
     4201 aaccatggga gagatgcctt ggcaaaagga agaacgctaa caagatttgc aagaaactca
     4261 accttaaacg agcttcctag tacgcttgca atggcaataa ctgtaaccac agcaattgtc
     4321 aactgcatac ctggttttga aagggcaaca aatttgttga caatgacaat cataacgata
     4381 gcaatcgtga ttgggtacaa gataaccagt actggaattg agtacttgat aatcgcatca
     4441 agacccaaat tggcaatagc aaatccaatc aaggtaaagg ctgtcgcata aaccttgtag
     4501 ctgatttgtg ggaagcgctc attaaagaac tcagctgttg acacaatcaa accaacagtc
     4561 gttgtgaagc aggttacggt aaccatagct gcaaggaaga gttgagctgt tgagccaaag
     4621 atttcttgag tggcttgtga caagatgtaa acacctggtg ttccaccctt catcgcttca
     4681 gctggtactg ggaaatgatt tccaagaaaa cctaaaccga tgtaaagagc gctgaaggca
     4741 agggcaacaa cgataccaac aacccaaata gttgaaatgt attctttctt acttgaaaat
     4801 ccaagttgtt tcaaggtttg aactgcgatt acgctaaagg ccactgaagc aagggcgtcc
     4861 aaggtattgt aaccttctag gaaacctgta ccaaaggcag aagcttgata agcagctgaa
     4921 gcagcttgag gacttgttcc accatatttg atagctccca gaacgaccaa gataacaatc
     4981 aaaattgcaa agactggcgt taaaacacgt ccaatgcggt ctaagatttt tgatggatta
     5041 agcgaaatca aataggctgc cgcaaaatac agaaccgtaa atacaatcaa gccaagtcct
     5101 ttatttgcat ccgacaaaag ggggctaatc cctacttcgt aagctgttgt agcagtacgt
     5161 ggggtagcaa agaatggacc gattgacaag taaagaactg agaggtaaag agtcgcaaac
     5221 caaggcgcta tcttcgttga aatctcgtag atatatcctt taggatttag cgttccaata
     5281 ataagggtca agacggcgat accaacgcct gaaaagacaa aacctgcgat ggcaggaaga
     5341 aaatgttctc cagatagagc acctagagaa ggcggaaaaa tcaagttccc cgcaccaaaa
     5401 aatattccaa acaggagcaa acctgttagg gtaccttttt tagccataaa aatctccttc
     5461 atatttataa aatactgacc tagtatacca cgattgggag tctgaaaaaa gcatcacgag
     5521 gcaaatatta aatgttttca attttcttaa aaataagaat tatctaaaaa taaaactctc
     5581 ctacccagtc cacaccaagt aggagaaatg caaaatttta aagttcttca aaggctaaca
     5641 tgccaccctg gacattgata acattataac cttgttctaa caggaattgg caagcacgcg
     5701 ccgatctcat tccagatttg caaataatat aatgcaagcg atctttgtcc aattaatcat
     5761 aactatcagc caattgacta agcggtaggt tgtgggcacc ttctaaatga agagctgcaa
     5821 actcatccac ttctctcaca tccactagag aaagctggtc gttttggtaa agctggtaaa
     5881 atgcgtcaaa ggctatttct ttcattcttt ttcttctaat actcttcgaa aatctcttca
     5941 aaccacgtca gcgtcgcctt accgtgcgta tgttaccgac ttcgtcagtt ttatctgcaa
     6001 cctcaaagct gtactttgag cagcctacga ctagcttcct agtttgctct ttgattttca
     6061 ttgactataa aatggtttta attctttttt tcaaatctgg cactacttct gcctcaaacc
     6121 aaggattttt ggccatccag atttgatttc gtggtgatgg gtgaactagc ggaaaatagg
     6181 ctggcagata gtctttatag tgtttcaccc tctccgttac cttcccactg attttctcct
     6241 gtaaatagta ggcttgggca tattgcccaa tcaagagggt taactgaata tcaggcaatt
     6301 cctgtaagag ctgcggatgc catttttctg caaaacctgt acgaggcgga agatcacccg
     6361 acttgccatg tcctggaaag tagaaatcca taggcaaaac agcaaaataa cctgaattgt
     6421 aaaaggtatc ttcatccaca cctagccagt cccgcaagcg gtcaccactt ttatctttcc
     6481 agtaaaggcc tgcttcttga gttttaagtc ccggagcctg accgatgata ttgatgcgag
     6541 cagtttttgg cgctgcaaag agaggctcaa tgccacgctc tgtatagctg gcattctgtg
     6601 aatccgccat gatagcctgt ttgattcttt cgatttgaga catctacttt ccctccaaaa
     6661 agaagtccaa gcataagatc tcagacttct atcgttttat ttgatcaatt cgtaaatagc
     6721 ttcggcatag attgctgctg ctcggaagag atcgtccaag gcgataaatt cattggcttg
     6781 gtgcatggta tcaattgagt ctgggaacat agcaccatag gcaactccgc gctctaacaa
     6841 gcgaccaaag gttccaccac cgatgacttg ttcatgacct ttaaagccag tttgtttttc
     6901 atagatattc aacaaggttt gcacaagtgg atcttccatt ggcacatagt gaggcgtgtg
     6961 accgtgttca gacaggctaa cagaaacaac tggcaagttt tcaaggattg acttgatttg
     7021 ttctggactt gttccttttg gatagcggat gttgagggca atggtattat cagcacttgt
     7081 ttcatcgaag cggaagacgc cggcattcat agaaagagca cccatctttt catccacatg
     7141 agcaatctta agattttcac cctcatgatc gttcaagaga attttacctg cgatgtcaag
     7201 gtagtctttg gctggaccag caaagccaaa ctgactgagg aagagggcaa ggtaagttgc
     7261 gccattgaca cctgaagcag gcatagcacc gtgggctgat ttaccaatga tcgtcacctt
     7321 gtatttgcca gcttcttctt ggagttctcc tctaagtttg tgttctgcaa caaaggcatc
     7381 tagtttagct tgcaagtcag ccaagtcacc tgaaacgact gctgttgctg attctggtac
     7441 catattttca cgtaaaccac ctgtaaagct gtgaagacgg gcaacacctg tattttctcc
     7501 tgcaaagtgg aggtattccg tgatatttcc tttttcacca ttgatgattg gaaattcagc
     7561 atctggtgag aaaccgaaat ctggtttggc aagtcctacg tgctcaaagt agtagtccat
     7621 gtctgcccag cctgattctt cgtctgttcc aacgatgaag cgaactttct tagaagttgg
     7681 aagacccaat tctttgatga ttttcaaacc atagtaacaa gctgttgtag gacccttatc
     7741 gtccgaagcc ccgcgcgcat aaaggcgacc atctttgata gttggtgtgt aagggtctgt
     7801 gtcccaaccg ctaccagcag gcaccacatc catatgggca aagattccga gaacttcttc
     7861 tccatcacca aactcaaaat gtcctgcata gttatcaaca ttcttagttg ggtagccatc
     7921 gcggtctgcg atttcaagga atttctccaa ggcttttact ggaccaggcc caaatggatg
     7981 ctgggcatca gccttgctgt catcacgttc tgaattgatt tccaaaaggc taaacaagtc
     8041 agccaagagg tcttctttgc gtttttctac ttctgctgta aaatcaattg ctgtcatttt
     8101 ttcttctttc tatcttttct cgatgatttc atctactggc aagcggtagc ttggttccaa
     8161 tttttcgtct gtataaccca ctgtgatcaa gagttctggg cggaaacggt cttcgatttc
     8221 caaaacttca ttaacttttg atttgtcaaa accaagaata atgttagaac caattccttg
     8281 gtctgtcaat gcaagaacca agttcatggc aaccaaacct gcattgagag ctaggtagtc
     8341 gctgacttgt tgttcattgt agcgtgcaaa ttcagctggc aaatttttca tgaagtattg
     8401 aagttgttct tctgagaaat tgttagcacc accaactcgg gcaatcttac gagcgcgttt
     8461 ggcaaggtct gtatctgtaa atagggcaat ggttacaggt gctgatgata cctgctcaaa
     8521 gtttgaacca taagccaact ttgccagttc agcatttttc tcacgaacaa ctacaaattt
     8581 ccaaggctgg ctgttgtggg cgcttggcgc caaggttgca atttcgatag ccgtacgcac
     8641 atcttttgga tcaacaggct tatcagtgaa atgcttggtc gcatgacgtt ttttatttaa
     8701 ttcaagaaat ttcataatcg atttcctttt ctaattctac tgcttccatt ctaccataat
     8761 ttgaaagagc ttgcagggat ttttcatgat taagtttttc tatcacagac ataaaagata
     8821 tatattggtt tatcaggaaa gtttctgata aactagcaag tactttacat ttgaatggag
     8881 acagtatgaa aaaatttagc ctattactag ctatcctacc atttttggtt gcctgtggga
     8941 atcaagctac acccaaagag actagcgctc aaaagacaat cgtccttgct acagctggcg
     9001 acgtgccacc atttgactac gaagataaag gcaatctgac aggcttcgat atcgaagttc
     9061 taaaggcagt agatgaaaaa ctcagcgact acgagattca atttcaaaga accgcctggg
     9121 aaagtatctt cccaggactt gattctggtc actatcaggc tgcggccaat aatttgagtt
     9181 acacaaaaga gcgtgctgaa aaataccttt actcgcttcc gatttccaac aatcccctcg
     9241 tccttgtcag caacaagaaa aatcctttga cttctcttga ccagatcgct ggtaaaacaa
     9301 cacaagagga taccggaact tctaacgctc aattcatcaa taactggaat cagaaacaca
     9361 ctgataatcc cgctacaatt aatttttctg gtgaggatat tggtaaacga atcctagacc
     9421 ttgctaacgg agagtttgat ttcctagttt ttgacaaggt atccgttcaa aagattatca
     9481 aggaccgtgg tttagacctc tcagtcgttg atttaccttc tgcagatagc cccagcaatt
     9541 atatcatttt ctcaagcgac caaaaagagt ttaaagagca atttgataaa gcgctcaaag
     9601 aactctatca agacggaacc cttgaaaaac tcagcaatac ctatctaggt ggttcttacc
     9661 tcccagatca atctcagtta caataacact cttcgaaaat ctcttcaaac cacgtcagct
     9721 ttatctgcaa cctcaaagct gtgctttgag caacctacgg ctagcttcct agtttgctct
     9781 ttgattttca tattgagtat aagatatatt aaaagcgatg ggatcagcca atcgcttttt
     9841 tagtttgcat tggttatttt aggaaactct tacaaaaaat caaaaaaatt cttcacatcc
     9901 tctacatacc tatgcttttc tattaagctt gctaatagtt ccagattgtg cctctgatag
     9961 ttatcttcac gacgtagttc ttcatacatt tcgataaagg gaaaaccctt ggatttggca
    10021 aattctaact cagcctcgta atcataagcg actttacgaa ataggatatt taccaattcc
    10081 ccatcttcaa cctctatcac ggcatactgg gcacggtgat tttttaacgc ctcccaatta
    10141 aaatagggca tgccaatcga ccctggattg atgatttgtt gcccttgact accataacga
    10201 agcaactact tgtgaacatg accataaact gccacgtccg tttccgcatc tagcagttgg
    10261 tcaaatttct ctgtatcatt ctcaactagc aagtcaccac catagttttt gtcaggtaaa
    10321 ttatgagaga tagaaaagcg caatccgtca atttctttct tttccagcaa aggcaagctt
    10381 cgtagccaga caatcgttgc aggatccatt cgctccatca aatactgtgt catacgcaag
    10441 agctgaactt cctgtgggtc ttctaagcca tattgcccat ctaaagcctc aaggacacaa
    10501 tcatcccaat tgcctcgaac acttgccgtg ataggaagtt cctttaacag agcgaccaag
    10561 tcatttgcac ctggaccagg gaggaaaatg tctcccatga gccaatattc actggctcct
    10621 tgagttttag catctgcaat cactgcttct agcgccgtcg cattgccatg aacatctgat
    10681 aaaattgcga ttttatggtt tattgtggtt tccttccgtt tggtaatcta ctctttcttc
    10741 cgccacttga agcaagattt ctgtttcctg cgggttcaac ttggtttgca cagcctctgc
    10801 tactgctctt ggtactccaa cttcgacaat ctcatccaca ctggcttcct tgattttggt
    10861 cagagacttg aagtgcctca tgagattttg cttgcgttta ggtcccagac catcaatccc
    10921 atccaattga gatgagaaag aatttttgga gcgcagttgg cggtggaagg taatggcaaa
    10981 gcggtggacc tcatcttgaa tgcgttggag gaggaaaaat tcctgagaat tgcgagacaa
    11041 gtccaccact tccagcggat ctccaaagag caattcatgg gtttggtgct tatcattctt
    11101 ttgcagacct gcaattggaa tatccaagcc cagttcttct tggatgactt gcttagcaat
    11161 attgacttga ccttgccccc catcaatcac aatcaaatct ggaggagtca aagcctcacg
    11221 ctgtactcga ccatagcgtc tgcgaatgac ctctcgcata ctggcatagt cgtctggccc
    11281 gactacggtc ttgattttat acttacggta atccttctta ctaggcttgc cgttgacaaa
    11341 gaccaccatg gctgaaacag gactagttcc catgatgttg gagttatcga aggactcgat
    11401 gcgaactggg gttgggattt gaagcaagcg tcctaaattt tcaatagctc cttgggtctt
    11461 ctcgacagat ttctctagca ggttgaactt ctgctctagg ctaacacggg cattttttat
    11521 agctaaattg accagctgct ttttctctcc acgttgaggc ttaagaatct tggaatccac
    11581 caaggccttg acagcctctt cgtcaatatc ctgcggaatc agtacctcat tgggaactag
    11641 gtgagatttt tcttgataga attgtcccac ataggtcaag aaatcctcat ctggatcatt
    11701 gaagtagggg aagagattga catcgcgctc gatgagcttg ccctgacgaa caaagaaaac
    11761 ctgcacacac atccagccct tatccacata gtagccaaag acatcgcgat tttggagatc
    11821 cttagccatg acccgttgct tggttcgaag cgttccaata gcctgaatca ggtcacggta
    11881 ttccgccgca cgttcaaact ccatagtctg ggctgccgct gccattttgc cctttagctc
    11941 atcaatgatt ttgttatcct gccctttcag aaaatcagaa acctcctggg ccatagactt
    12001 gaaataagcc tcatccttct tacagatggt gtgagccata cactggccga tatggtaata
    12061 aaaacagacc ttagagggcg ggttggtaca cttacgaaaa gggaatatcc gatccagcaa
    12121 ccgcttgatt tcattggctg cccccacatc gggataaggt ccaaaataaa gacctccgtc
    12181 ctttttgacc tgacgagtga taatcaagcg tggatagcgc tcattggtga ttttgatgaa
    12241 aggataggac ttgtcatcct tgagcatgat attgtacttg ggcttgtttt ccttgatcag
    12301 gttgatttct aggagaagtg cctcaatatt agactccgta acaataaatt caaaatccac
    12361 aatttcagac accagagcct ctgtcttggt atcatgactt ccacgaaaat aggaccgtac
    12421 tcgattacgc agatttttag cctttcctac atagataatg gtgccatttt tatccttatg
    12481 aatgtagcaa ccagggctgg tcggcaagag ctctagtttt gatttaatca agttgttcat
    12541 agttccatta tagcaaaaaa agtagggaaa gatagtaccc tactcactag tctcatatat
    12601 ttttcggagg tttgcaacat cctcttcctg gataccataa aaggaacctg ctggttgcat
    12661 gacagacttc tcatctgtat ggtccaagcc aatcgcatga cctaactcat gttctgccgt
    12721 atggacaagg cgttcatagg agtagccata gtatggattg gacaaataat aatgattcaa
    12781 ccgcaccgtt acggacaaga attgccctgt taagagatta gtttgacttt ccgcctctcc
    12841 tgccacagga gtgcctccgt cgttcatctc cgtagccgta atatccgcct tactagactc
    12901 agtcacgagt tcaaagttaa aagcaccagt ttgattccag ttctggattg cttctaaata
    12961 agcctcttga aagcgtgaat ccatctgcgg atccaggtaa atacgagcag agacctgtgg
    13021 ccaccttcct tcagaatgct ggtgactatc tgtctggctt aacttaggca gttgccctgt
    13081 tttctcccat tggtcaatac tttgttgacc aatttttact gaccgttctg cttgctttag
    13141 cgctccttga aaatccccgt tcagatacca gagaagtccg aaagcaagca cacataagag
    13201 cacaactatc caaaccagac gccaaaacaa acgccacaca aaagaaaaga aagcccctat
    13261 caaacgaaaa agccagcgca tgtctctcca cctttctagc aaataaaaat tattttacta
    13321 aaagaagcta aaagaaatct aaatactgac tttttcatct taacgtccta ctattttttt
    13381 gagtaactgg atagctttgt attttaaagg cgatggatgg taacggaaag tacctgcttt
    13441 gcgtacaata tagccattaa aattctgttt aaaacgcaaa acaccatcac ttccatcaaa
    13501 aatcccttga atgcctagga agttgtattt aggtattcca cgttttatgc ttttcaacat
    13561 aacatatttt tgaagcagtg caggggcata gaacttatta aactcagtgt aggaaccact
    13621 aaagagataa gtcgtttcct gaggcatata aacaaataaa ctcccagcta aaacaatatc
    13681 ttcttctcca tatttttcaa tcaagtctcg cgcttctgct tttcgaactt caaacgtttc
    13741 aaattgacta gaatattctc tcagttgatt ttgttttttc tcagaatgag gatttttact
    13801 caaatcaagt cgcaacttgt ccaagttttc ttctagttta ctttgttcac cttgcaattt
    13861 gctcatatag tccgaaaaat tcaagcttgc tatgagaaac tccgcttgtt ctccaaaagt
    13921 atcataaaaa tgctcataat attctaaact tttatcacta tattctctac gttcagaggt
    13981 ttcttttgtt atattcttaa aaatcgatag ttcttcacgt tttaactttt tcaaccgaat
    14041 gccaaaggtt tcagcctttt tcaccaaggg tttacccttt ttgctaaaac ttttaagcaa
    14101 actcttttca gttaattcag ttaaatcttt atagtataac caatctggtt ctccacctgg
    14161 gtaacctgtt gttaagccat caaattgata acctaaatca gtcaaacctt gaataatact
    14221 ttttttctca gcatctattg gattaccttg gctatcaaaa gtttgataag tttcataagg
    14281 ttttacaagc aactctaata caccattttg cttggcatat tcttttaact ctgcataaaa
    14341 aactggaaga gcatcttgtt gggtataaat cggccccgaa ttgagttcca tatgcagacc
    14401 acccagcatg ggcaagctat aaaccagagc tgcaacttga atttctcctt cttgtttcaa
    14461 agcaagataa acaattcgag cccctctttt ttctagcaaa tcccccatct ggacagattg
    14521 cataaaggaa cgagaagaaa cctgatcaga ataagtctga aactcttctt tcgtgagtgt
    14581 tgttagtgcc atatacttac tttctatgtt tttttcttaa tgttttacgg aaatcaagag
    14641 caagtcttaa cagaggatag agaggatgag tgggcattgt aaattcaccc aagtattctt
    14701 caatcgttgg attaaatttt tccttaaaat gataaagtcc accattgaga gagttttcaa
    14761 caccacctaa attttgccag accatacctc gctcaaaggc atagcgagcc gtttcatacc
    14821 atgttaaaat tggtgcattg taacgtttaa aatcatcatc cataccagca tatatattga
    14881 cagaggtagt accaaattcc aaactcaaag tagccgctaa aggaactctc gcttgaccta
    14941 catctatata ttcctgcaag aaggtcaatt cctctaacaa acgttctttt tccttcttct
    15001 gcgcttctac ttttgaaatt cgagtcgact cagtaaaggt ctcttccaag gctctatttt
    15061 tcgctaactg ttcttctaac tcttgcgaac gtttagaaac atccaaggtg gccaaggtga
    15121 tataggcctt gtccttaaaa ttatctaaca attttttata ataggcttca ttcctcaaat
    15181 gaatctcttt tcgcttctca gtttttttca tcaactccga aaatgaatct aatagttcca
    15241 gtccaccata ttgaatctca agccctttgt ttcgtgctgt tcgaatagcc tgttttgttg
    15301 acttggaaag tttatcttct tcaaaatttt ccttgtatat tttcgcctga atacgaggtt
    15361 gaatggtgtc tcccatttcc tccgtttttc ctgaccacct tactcccatt tgttgcaaac
    15421 tatcaataat agccagattt tcaggaaatt ctgtcttttc ctgattgatt aaactttgag
    15481 ataggcaaat acttgggtca aaagtcacaa aaaccgctct cttactgcga gcataggact
    15541 taatagactg aatggcaaaa ttcaagagtt ctttatcccc ataatccaat ataggtcctc
    15601 ttgggatgta aaacatttta tagcctagcg gaagagttct aatcaaaata ctagctgtcg
    15661 ccagtaattt ttcttccctg taaacaccaa acttctcatg ttgccaatta gacttaactt
    15721 cctcccaagc actactttgt aatacattgg ctaattcatg ttctttgaca aactgatcat
    15781 attctaatgt gggaatgcca atttgataac ggtacatttc ctactctctt tcctccagta
    15841 ttttattact attctactac tttcgtttga aaagtctagt gaaaacatat tttattttag
    15901 ttctacttcc cctatgctga agttcaaact aagtcagtct ctcttctaat ttgaaatcaa
    15961 ttggtagggt tgttaaaaaa acttccaatt gtttttccca gtagtaccac tcgtgagttc
    16021 cagcgctatg gctataggtc acatcaaaac ctagtttttt gagatttttc actgcaagat
    16081 tattggcttc gtacaagaaa tcctgttcgc cacaccacgc ccaaagtttg gtctttttat
    16141 ccgatttttt agccagactt tcaagagaat agggactagt tgtccagtct ttaatctctc
    16201 caaaaacacc tctccagtag gctggcgttc ccagattttg actctcagga gaaaaatctt
    16261 gaaagctcaa tgcacctgaa aagctagctg catgagaaaa acgatttgtc gcaagagcca
    16321 gtttgaaaca gccgtagcct cccatagaaa gaccagcgat aaaggtcttt tcacgcttgc
    16381 tagtcatatt agggaagaag cgtttcagaa cctgtggcaa ttcctctgct agagccgtgt
    16441 agtagtcaaa accatactgg gtatcggtgt accaaccatt gctggtattg ggcataacaa
    16501 cgatgagatt agttcctcga agcaagcgtt ctacattggt ccgcttaagc caactattat
    16561 gattgccaga catcccgtgc aaaaggtaca agacgggaat atcttcacac tctggttctt
    16621 ccactcgatt ggcatcaggg tagaggacat tcacccccca ctccatatcc aatacttgtg
    16681 agtaatactc gattttcatt actgccatga ttttctcctt ctatttttct ataagaaaaa
    16741 gccgaaactc gactttctct ctgtttattt taacgattat tttgcttcca tgactactgg
    16801 taaaatggct gggcgacgct tggtttggtc aaagagatac ttggtcaaat tatctcgaac
    16861 cttcccttta agatctgccc agtcaaagtc atctccttga agatactctt ctaccgtttg
    16921 gttaatcaat tctgaacttt cacggagaat atcgcgactc ttcttgagat aaacaaatcc
    16981 acgcgtgtga acacgagccc tagccacaat tttcttctca cgacggttga ctgtaatagc
    17041 cacgatgaaa attccatcct ctgacaagac cttacggtca cgaagaacaa catttccaac
    17101 atcaccaatg gcattcccat caatcaagat atctcctgct gaaaccgatc cagctggaac
    17161 aaagtctcca ttctcgtaag ccatggtcgt ccccttttta ggaatgaaga tgcgttctgg
    17221 caacatccca actgccatgg cagccttagc gtgagcatcc aactcacgat actccccttg
    17281 gacagggaag aggtacttag gttgcaaaag attgatcatc agctgcaaat cacgcacatt
    17341 tccgtgccct gatacatgta aactttgggt aatcaatttg acaaccccac ctgcctgata
    17401 aatcatattt tccacacgcg caacaaaggc ttctttagca atagacggag ccgtagcaat
    17461 atagaccagg tccccatcct tgatttctac ataacgatgg cgaccaatcg acatcttacg
    17521 aagtccattg ataggttcac ccatacgacc tgtctcaaga ataatcaact catggtcttc
    17581 aaatcgagac atatctttag gcttaatcaa gagaatttcg ttggctaaag acaacttctt
    17641 aagacgaatc gctgtgcgga cgatattttc aatatcaaat cctgtcaaga cgatacgtcg
    17701 acctgtttta tccgcagcgt caaaaatctg ctgaatacga gaaagattac tggaaacagc
    17761 tgcaacgatg atacgacctt cccagtcagc aatagtttgg gtaatttcat ccctaacttc
    17821 actttcacta gccacctgaa tattgctgtc tgcattggcc gaatcactga ggagagccag
    17881 gacgccgtca cgaccaatct ctgccaaacg agcaaaatca gttgcataag attcactagc
    17941 cgtttggtca aatttgaagt cacctgtata aacgatgctt ccttccgatg tcttcaagac
    18001 aattcccaga ctctctggaa cggagtaagt cgtagggaag aaggaaacca ctgtcccacc
    18061 aaaatcaatc tccgtattct catcaatgac atggaaatca ttaaatttct taacggcatc
    18121 atttcctttg acaaagagct ttgccaactc aatggtcaac tcagacccaa atacaggaac
    18181 tttagcctct gccaagagat acggtagagc accaatggca tccgcatgcc cgtgggtcaa
    18241 gaaaacccca gcaatacggt cgctattttc aaaaaggtaa tccatgtttg gaatcaccac
    18301 atcgacccct aattgttcat tttcaggata ttttaaccct acattcaaaa caaaaatgga
    18361 ctctccaatt tcagcaatgt acatattttt tccattctca cgcacaccac caagtgttgt
    18421 taaactgata ttactcattt ttcctccaaa atcttagttt atcttgatta tagggcaatt
    18481 ctaccctctt attctaaaag ttctgatact ttcagccgaa tcttttccta ccattatacc
    18541 atttttttga tgattttcaa aatgaaggtc tgttttcaaa aaagagttga tttcccaact
    18601 ctttcctaac ttctactctt tttccatcaa aaaatcataa atttcttgca ccgtacccag
    18661 cgccatcatt tcttggtctt taacggtttg tttgagattt tggtaaattt gactttctcc
    18721 tatctcccgc tttggcgcct ctttattgac tgtcatcaca ccatctttta tcgtcacaaa
    18781 gcctagttct tcaaatactt gaatcatctt gaccagcaag atttgttgaa tattaagata
    18841 tgcagccaaa tctttcagct tgtagcgaat atcaaactct gggaaccggt aaatagtctt
    18901 gtacaatttg gcaaactgat ctctagtccc ataacctgtc agataataag ccttgtcaat
    18961 atcatttttg aaatagacag cagagaaatg ctgttcctga aaaatggtct tcagctgagt
    19021 aatatcctct ggaatgtttt ttacgacaac agcttcacta gccgcaagat ttggcagttc
    19081 tccaggaaaa tccaagactg gaacaccttc tggcaagact gcattttttc cacgaatgtt
    19141 aaaaagttga acaccttcca ctcgcgcatc caccatcatc aactggaggg cagtttggcc
    19201 attccattgg ttgacagaca atttaaccgc taactctaga ttcttggttt gagaaaactc
    19261 tgtcgcccat ctgccttgac caaaggctac cacttcaaaa ctcgcctcac ccttggaaat
    19321 tttcagcttt agatgggcat tacctgcccc catagtacga gcactttcga cctgaaaatt
    19381 cttgatataa aaaataggtt tctgattatc cattccaaaa ggagctaaac gttcaaaact
    19441 tttgaccgtt tccaagctaa gtgcctccaa atccaactct tcatctaggt ttaacttatt
    19501 cttgccacca gcatctgcac ctttttcacg aacataatct tccaaaacct gagataaatc
    19561 tgagagttgc tcaacttcca acgtcatacc cgctgcacct gcatgacctc caaaggcgat
    19621 gaagaggtct cgatggggat ccagagcttc aaaaatatcg accgcttcca cactacgagc
    19681 actgcccttg gcacgaccgt cttctatatt aagaacaatg actgtctgtc ccaattcttc
    19741 caataaacga ccagccacga ttcctagaac cccaggattc cagccttcct tggccaagac
    19801 ctgaaccttc ttctcaggat ccaccatggt cttggcttct tcatagatag actgaacgat
    19861 ttccttgcgc tcttcgtttt tctggtgaat cataagggca atctcatgcg cttcctcatc
    19921 atcaaatcca gtcaacaaat caatggcagg attgggatca tccaagcgac ccaaggcatt
    19981 caaacgagga gcaatctgga aaccaaccgt ttcttctgtt acttcgttgg caccaatccc
    20041 agccatgtcc agcatttctt gcagaccaat gcgctgggta tgacccaaca tttccagacc
    20101 atattgaact aagatacgat tttcatccgt cagactcacc atatctgcaa tagttccaat
    20161 agcgaccaaa tcaagcaatt ccacttgcac ttcttctaac agggcacaag ccaacttgaa
    20221 agcaactcca caaccagcca aatatttaaa aggataatcc gcatctggat gttcaggatg
    20281 gacaatagca taagcatctg gcagggtttc aggcatggaa tgatggtctg tgacaatgac
    20341 atctactccc atagactgag ccaatgcaat agcctcatga ccagcaaccc cattgtccac
    20401 cgtcacaatc aaggaaatcc cttcttgctc gataaagtat ttataaacac tagcattagg
    20461 gccatagcca tcggtaaaac gatttggcag gtaaactcgg cactcagcac caagttgttc
    20521 caaactttcc ttcacaatag aagccgaagt catgccatcc gcatcatagt ctccataaac
    20581 gagaatattt tccccttctt caatagcctg acgaatccgc tccactgcct tgtccatatc
    20641 atggagcaga taagcatcat gtaagtcctc caaggaaggt tctaaaaact tcttcagact
    20701 ttcttggtcc tgaatccctc tctcaaacaa taaccgagcc acctcaggac ccagtccagc
    20761 cttcttggct atctttgtaa aatccgcatc ttctacctgc agggcaaact gccattcata
    20821 agtaggtgtt atcaaaaaga catccactct ttctaagaat tctattgctt cattataaca
    20881 tgatttagac gttttctcta tccagattgc ttttttataa cattttatag tatattgaaa
    20941 ctagaatagt acacctctac ttctaaaata ttgttagaaa tcgatttgac tgtcccgatc
    21001 gatttgtcct gttcttattt caatatagtg aattttttca gatatggttt gacaagaaca
    21061 ttcttttatt gtagaatcgt gttataaaat ctaacataaa ggagatctct catggcttta
    21121 gtagaattta aaaacgtcga aaaatattac ggagactacc acgcactccg caacatcaat
    21181 ctccgttttg aaaaaggaca agttgttgtc ctgcttggac cttctggctc tgggaagtcc
    21241 actcttatcc gtacgatcaa tggtttagag gctgttgaca aaggaagtct cctagtcaat
    21301 gggcaccaag ttgctggtgc cagccagaaa gatttggtac ctcttcgcaa ggaagtcggc
    21361 atggtttttc aacattttaa cctttataca cacaaaactg tgttagaaaa cgtgacactt
    21421 gcgcccatta aagttctagg aattgataaa aaagaagctg aaaaaaccgc ccaaaaatat
    21481 ctggaatttg taaatatgtg ggacaagaaa gattcctatc ccgccatgct atctggtgga
    21541 caaaaacagc ggatcgccat cgctcgtggt cttgctatgc atccggaact cctcctcttt
    21601 gatgaaccaa catctgctct tgatcctgag actatcggag atgttctagc agttatgcag
    21661 aaactggcgc atgatgggat gaacatgatc atcgttaccc acgaaatggg ctttgctcga
    21721 gaggttgcgg accgcattat ctttatggcc gacggagaag ttttagtaga tatgacagat
    21781 gtcgataact tttttgacaa tccaagcgaa cctcgtgccc aacaattcct cagcaaaatt
    21841 atcaaccacg aaagtgacaa agtcaaataa ggaggcgcct atgaaaaaaa aattcttttt
    21901 atcagcatta ttgattagcc ttttcggcct tgctgctgcc aaaccagtcc aggctgatac
    21961 tagtatcgca gacattcaaa aaagaggcga actggttgtc ggtgtcaaac aagacgttcc
    22021 caattttggt tacaaagatc ccaagaccgg tacttattct ggtatcgaaa ccgacttggc
    22081 caagatggta gctgatgaac tcaaggtcaa gattcgctat gtgccggtta cagcacaaac
    22141 ccgcgccccc ttctagacaa tgaacaggtc gatatggata tcgcgacctt taccatcacg
    22201 gacgaacgca aaaaactcta caactttacc agtccctact acacagacgc ttctggattt
    22261 ttggtcaata aatctgccaa aatcaaaaag attgaggacc taaacggcaa aaccatcgga
    22321 gtcgcccaag gttctatcac ccaacgccta attactgaac tgggtaaaaa gaaaggtctg
    22381 aagtttaaat tcgtcgaact tggttcctac ccagaattga ttacttccct gcacgctcat
    22441 cgtatcgatg ccttttccgt tgaccgctct attctatctg gctacactaa taaacggaca
    22501 gcactactag atgatagttt caagccatct gactacggta ttgttaccaa gaaatcaaat
    22561 acagagctca acgactatct tgataacttg gttactaaat ggagcaagga tggtagtttg
    22621 cagaaacttt atgaccgtta caagctcaaa ccatctagtc ataccgcaga ttaaggagga
    22681 taccctatga cagatttatc atcttggaca gcctattttc aggattttgg acaatttttc
    22741 aatggtttcc tcttcaccct tgccctagcg attggatcct ttatcctcgc catggtctta
    22801 ggaatcttct ttggtgccat gtcaaccagt aaacgtccaa ttttacgcat tttagctcgc
    22861 atcttcgtgg aattttacca aaacactccc ctcttggtgc agtttgttat tgttttttat
    22921 ggcctacctc ttatcagtga ccatatcatc atgattccaa tttattggac agccgttctc
    22981 tgcgtgggac tctatcacgg cgcttatatc gctgaggtta ttcgttcagg gattcagtct
    23041 attcctagtg gtcagatgga ggccgccttg tcgcaaggtt ttacctatat cagtgccatg
    23101 cgcttgatta tcttgcctca ggccttccgc atcattctcc ctccattgac caaccaaatt
    23161 gttaacctca tcaagaacac atctactgta gctatcatct ctggagtaga cttgatgttt
    23221 gtgactaagt cttggtcggc tctcaacgga aactatatcc cagccttttt aggtgctgct
    23281 cttctctact ttgccctatg cttccctgtt gcccagtttg gtcgcaagat ggagcaagtc
    23341 aataaaaaag cctattcact ttaggaggtt actatggaat ctattttaga aattttaacc
    23401 ccagataacc tagtctttat ctttaaagga tttggcttga ccctctatat ttctctgatt
    23461 gccatcatcc tctctactat catcggtacc gtgcttgccg tcatgcgaaa tggaaaaaat
    23521 cctatcttac gcattatttc cagtatttat atcgagtttg tgcgcaacgt tcccaacctt
    23581 ctctggattt ttactatctt tttggtgttc aaaatgaagt ccacaccagc aggtattaca
    23641 gcctttactc tctttacatc agcagccttg gctgagatta ttcgaggcgg tctcaatgcc
    23701 gtagacaagg gacaatacga agcaggaatg tcacaaggct tcacctcagc ccaaatcctc
    23761 tactacatca ttctcccaca agccatccgc aaaatgctac cagccatcat ttctcagttt
    23821 gttaccgtga ttaaggatac cagtctcctc tactctgtta tcgccctaca agaactcttt
    23881 ggagccagcc aaattctcat gggccgttat ttcgaaccag agcaggtctt cagtctttac
    23941 atcctgattg ccctcatcta cttcagcttt aacctagcaa tttctaacct gtctcatatg
    24001 ctagcaaaac gttggcaaca agctgcagaa taacaaatta gctctctagt tcattggaga
    24061 gttttttgat gatagtagat atttatagac ctcaatttga caccatacat tttctatgat
    24121 aaaatgtaac aaatttattt acaacaaatc gaaatctaaa tgaaatggaa ttttctatga
    24181 aatcaatcaa aggactactc tttatcatag ctagttttat cttgactctt ttgacttgga
    24241 tgaacacttc tccccaattc atgattccag gactagcttt aacaagccta tctctgactt
    24301 ttatcctagc cactcgtctc ccactactag aaagctggtt tcacggtttg gagaaggtct
    24361 acaccgtcca caaattcaca gcctttctct caatcatcct actaatcttt cataacttta
    24421 gtatgggcgg tttgtggggc tctcgcttag ctgctcagtt tggcaatctt gccatctata
    24481 tctttgccag catcatcctt gtcgcctatt taggcaaata catccaatac gaagcttggc
    24541 gatggattca ccgcctggtt tacctagcct atattttagg actctttcac atctacatga
    24601 taatgggcaa tcgtctcctt acatttaatc ttctaagttt tcttgttggt agctatgccc
    24661 ttttaggctt actagctggt ttttatatca tttttctata tcaaaagatt tccttcccct
    24721 atctagggaa aattacccat ctcaaacgct taaatcacga tactagagaa attcaaatcc
    24781 atcttagcag acctttcaac tatcaatcag gacaatttgc ctttctaaag attttccaag
    24841 aaggctttga aagtgctccg catccctttt ctatctcagg aggtcatggt caaactcttt
    24901 actttactgt taaaaattca ggcgaccata ccaagaatat ctatgataat cttcaagccg
    24961 gcagcaaagt aaccctagac agagcttacg gacacatgat catagaagaa ggacgagaaa
    25021 atcaggtttg gattgctgga ggtattggga ttaccccctt catctcttac atccgtgaac
    25081 atcctatttt agataaacag gttcacttct actatagctt ccgtggagat gaaaatgcag
    25141 tctacctaga tttactccgt aactatgctc agaaaaatcc taattttgaa ctccatctaa
    25201 tcgacagtac gaaagacggc tatcttaatt ttgaacaaaa agaagtgccc gaacatgcaa
    25261 ccgtctatat gtgtggtcct atttctatga tgaaggcact tgccaaacag attaagaaac
    25321 aaaatccaaa aacagagctt atttacgaag gattcaagtt caaataagta atcatactct
    25381 cctgggattt cccaggagag ttttttatag ccaaatgaaa taagaccgga acgatggaat
    25441 tttggcattc aaatcaattg ataagaatat tttatagtgg agtgaaatag gatacgaaca
    25501 aattgattag gaaaatcaaa tgaatttata gaaatctttt agcagttatg ttgtcctatt
    25561 ctagtttcaa aacgctatgg aagcagcatt gtgctagtct agattcagtt tactatacta
    25621 aaacgagtag cttgaaatca aaaaacccac cctcacaggc aggttttatc tgtattattc
    25681 agctagatta tgctttacct tctgaaccga atacgtcgat acgttcttca accgatgctt
    25741 ggatagcttt tacaccgtca gccaagaatt tacgtgggtc gaagagtttt ttcttgtcgt
    25801 attctgcttc gtttgcttcg taatcacgag caaatttacg agttgcgtta gcgaatgcga
    25861 tttggcattc tgtgttaacg ttaactttgg caacaccaag tttgatagct gcttggattt
    25921 gctcatcagg aatacctgat ccaccgtgca atacgattgg gaatcctgga agagcttctg
    25981 tcaatttttg caagtggtca aggtcaagac cttcccagtt tactgggtaa gggccgtgga
    26041 tgttaccgat accagctgcc aagaagtcga taccagtttc aaccattgct ttagcgtctt
    26101 cgattggagc caattcacct ttaccgatga ttccgtcttc ttcaccaccg atagtaccaa
    26161 cttcagcttc tactgagata cctttagcgt gtgctttttc aacaacttct ttagccaatt
    26221 taaggttttc ttcaactgga aggtgtgaac cgtcaaacat gattgaagta taaccaactt
    26281 cgatacactc aagtgcatct tcgtagtgac cgtggtcaag gtggatagct actggtacag
    26341 tgatacccat tgattcaaca aggttagcga tcaagttgcg agcaactttg taaccaccca
    26401 tgtatttagc agcacccatt gaagtttgga tcaaaactgg agctttttta gcttctgctg
    26461 cgcgcaagat agcttgagtc cactcaaggt tgtttgtgtt aaatccacca actgcataac
    26521 cgttgtcacg ggctgcttgg acaaattttt ctgctgaaac gattgccatt ttatcaggcc
    26581 tcctgtatat ttttatgggt catcccattt acattgttca ttttatcact ttttgccaaa
    26641 aaaatctagt ttttcccgca gtttcgattg attttcttct aactccatct atgtaaaccc
    26701 tttctctccc tagtcttgga cgacttttgg aaaatctata aagaaggtta aacgattctc
    26761 ctccatctcg aaacgataag ctaatttttc atgttctaat agactcttaa ccacaaaaag
    26821 ccccatacca gaccccttga ccttgcgact ggcattgtca gaaaaagact gggctagttt
    26881 ttcttgttcc tctgagctac agctattttc gataaaaagt tctccttctc tttctccaat
    26941 tcgaactaag ccacctggaa cagagtgctt aatggcattg ctgatgagat tagaaagaat
    27001 caacttcata actgatgggt ttagataagc ctgctgatgg gtcaaactat tgtctatctg
    27061 gagctctctt tccttggcta gcaaggcata atctttgacc agatttttcg tcatctggag
    27121 gaggtcaatt gtttccctat catctcgcaa ttcctgcaca gaagagaggg aaagtatctg
    27181 cagaacatgg tgattgagtt catccacaat ccccaaggca actcccagat actggtctct
    27241 atccttataa cgaccgatat tctctctcat attttcgatt aggattttca aactagccag
    27301 cggtgttttc aattcatgag aagctcctcg taggaattcg accttcatct tctccagctg
    27361 gagaatggct tcattctttt catgcaagtc cgcaataaca gtcaagagat gctggtagag
    27421 gctattgatt tgttccttga gattacctat ctcatcctta gaatccacgc gcaatcgcac
    27481 ttgggaatcc aggtccatca tccgacgggt cacccgcttg atttccaaaa tcggtgcaac
    27541 aatagtccga gcgtagatgt aggccaccaa gagggaaatc agaaaggagg ccagcaaggt
    27601 atagggaaga aactggagac tgatttgctc cgcttccttt tgtaaatcca tggaagctag
    27661 aaactggaga atcatagtac caccgtcttg cgttttcacc tcgcgctcct caataaagag
    27721 agaggttgtc tggcggtctg tgtccagagg aagactgtcc ttgacttcta acttgtcctc
    27781 ggtcatctca cctttgacgg tccccttgat atcactagtc tgggaataca agtctaacac
    27841 ttgctcgata ctctgcctat ctttcccttc tagggactgg gcaatggctg ttgccttttg
    27901 accaatggtt tcctgacgat gactcagata agtcgaagga aaaagaaaat aaatagctaa
    27961 atgaaggcag ataaccagaa cactaaatat cgagaaggta tagataaata tctttgtaaa
    28021 taaacctgtt cgtttcattt tcgctccaat ttataaccaa cattgcgcac agtgaagata
    28081 caatccaagt ctagcttttt ccgcaattcc ttgatataaa catcaataac acggtcaaag
    28141 ggaacctcat ctgtcgcttt ccagacggca tcgataatct gagaccgagt caaggcccgg
    28201 ccttcatttt tcactagata gtccagaatt tccaactctt tggcattgat aggcacttct
    28261 tgacctgcga ggcttgcact gtagctttca aagtccacct tggtatcctt gtaagaaaag
    28321 attcgtcctg tatcgtagta gcgcttgaaa atcgcgtcca ccctcacttt taagagggag
    28381 agggagaaag gtttttccag atagccatct gccaaagagg caaaggcact catcttgtat
    28441 tcctcatcct gaaaagctgt caacatcaag acaggaacct gactggtttt acgaatctca
    28501 gctaggactt ctaagccgtt aagcttgggc atctggatat ccagtaaaac cagggccacc
    28561 tcatagctag aaaattgctc cagagcttcc tgaccgtccg ctgcctcaat agtttcatag
    28621 ccacaatccg tcaaataatc actgaccccc tcacggatca tctcttcatc ttctacaatt
    28681 aaaattttca tactttaact gctctctatt ttttattttt cttagaataa atacctactc
    28741 tattttctat tatagtctct tgctggcctt ttgtctgtaa gcaactgacc actagataaa
    28801 acgttgtgaa attcctttct cataaattcc ataactttag tatattatat ttaagcacta
    28861 aagtacaaag aaagcaactg aaagcaatga ttttcaccac tgctttcaga tttattttga
    28921 attgttaaat agctattcct atccactatt cttgaataga aacacaagat gcaatcttta
    28981 ttccagactc attttttcaa atttattcac catccagcaa gagctctttt ggttgttttc
    29041 taaggagatt gcttgaagca agcgccataa cgagaaccac tagaaccaag gcaaggacaa
    29101 aaatgatgat aaagtctgat gtctgaatgg aaatgtctag gctcgacaag gtcttgctaa
    29161 agccatctac ttctgcaccg ccaccaaggt tagaggcttg agccgcctta ctagcctgtt
    29221 tggcaacacc tgaagtcaca ttggcaagga cagtgtttcc aattgcacgg gcagtgtaat
    29281 tagctaggaa gtaagcagaa actagagcag ggatagcaat caagatagat tcggtgatga
    29341 attgacccaa gatacttgcc tgcttgaggc cgatagagag gagaattccc acttccttgc
    29401 gacgggcgtt gatccaaagg ctgagcaaga gggcaaggag gagaactgag aagctcaagc
    29461 taccccagaa gaggaggttg gccatcttgt acataccaga gatagattgc tcaagagctg
    29521 ggtagttaga ggagctcttg acgagtgtgt agctcttcca gttgatacca ctgatgccat
    29581 tcaactcttt cataacatca tccaagttct tgtctgctgt tacaaagaag gttgcgtccc
    29641 cataaatggc tgtgtcttct gtgtatccat aaagttttgc agcagtgtga atgtctgtaa
    29701 tagctgtgtt ttcgtaaagt tcttgtgagt aggttactgc tgacttatta tgaccatcaa
    29761 agagtccctt gattgtcact tcaactgttt ccttggctcc tttttcatta tctgcatcgt
    29821 agatattaga gtccagttta accttgtccc ctactttcca gccgtgtttg gctgccaagt
    29881 ccttgtgcaa gaggatttta tccttgtcgt cgttggttaa gtgctctcct tcgactagtt
    29941 tataagaacc agagacaaac ttgtcttctt tagaggagtc attgacacct gtaatcatca
    30001 agctacttcc aaaacgtttg gcacgatcag cagtgagatt cttcttggtt tctggcgttt
    30061 caatcaggtc atatccagtc aaatctccga tagcgttgat acgtttgaca taagactcaa
    30121 tggccttgtt ttcggtgatt tttttgatat cttcaccctt gatattccca gcaccacgag
    30181 gcgttccttg gttgacgcga cgattgattt gcatggagaa gctattggtg atatttttaa
    30241 aggtctcctg agaagccttg gcagtagctc ccttgattga caagccgacc aaactcaagc
    30301 tcgccatgag gagaataatc aggaagatga caatcgattt gaaaaacttc cttgtaacat
    30361 aggcaaatgc gttgtgtaac atagattccc tttctagatt ttgttttaat cattctatca
    30421 aaataagctc aaattattta ctagtattgc gcgtttcagt cagtttctta tcctttaatt
    30481 caagtgtaat atctgacgct tgtgccactt ctttactgtg agttacgaca atcacacatt
    30541 tacctgtttt ctgggcaagt gatttgagta gttcgacaat atctccagca gttttaggat
    30601 ccagatttcc tgttggctca tcagctagaa taactggagc ttctgagacc aaactgcgag
    30661 caatggcaac acgttgctgt tgaccacctg ataactggag aacattccgc ttgatctggc
    30721 tttcatccaa accaagctca agaagtgtat tcttgcttgc ctttttgttg accaatcgga
    30781 tattttccag cggagaaaga taatctatca agttataatt ttgaaagacc agggaaatat
    30841 ggtgcatgcg atggtaagaa tagcccttct tacgaatatc ctctccttga aaaaggatag
    30901 aaccttcaac aggactatct agaccagcaa gtagggacaa gagtgtggat tttcctgctc
    30961 ctgactcccc aataatactg taaaattttc cgggttcaaa attataatcg atctgatata
    31021 ggactgcttc agcagtattc ttataacggt aggtaacatc ttgtaattgt aataaagtca
    31081 tgatttctcc ttcttaacta atagatgata aaatttcttt cggtgatttt ctaaataaga
    31141 ataggaaaca aagggctaca gataagcaac taagcagaac tagaaaaaca taggattctg
    31201 caaaagataa gatgctagtt gataaactgc ttgctttggc tagtgtatct tgtaagctta
    31261 cctgatctcc acttgctagt agagtttgga gtaggtaagt tgtgattccg tttcctgcaa
    31321 caaatgctgg aagcaaagct ccaagagata ccaaaactac ctctaaacag aattgtagga
    31381 agatcgagct cttgcctttt ccaagtgcaa gtaaaatccc cacttcatag acccgttctc
    31441 tcaaccagag agacaaaacc agaattaagg ctccagctcc tgctatcaac atcccataaa
    31501 ggaagatggt caggaaggtt tggaaagttg caactgagtc tttgatttgt tcaaaagcct
    31561 tgttttcctt ttcgacttgg tagccttgat tttccaaggc caagttttct acctgcttca
    31621 tgagtccgtc catttcctta ggattttcta catagaagcg tgctgcactg acttgagctt
    31681 cactattgcc caaaagggtt tggctacttt cataatctgt aaagacttga ttttcactga
    31741 agtcagaaga caagcctgtg aatttctctt gttttttacc agaaaagatg ccgataatct
    31801 caaactctac tgtttgtcct tttccagatt cagactgacc agcatccaag ccaatcttgt
    31861 catgaagtga aagaccgttc ttcttagcca attcttcgtg gataaggatt ttcttggaat
    31921 cccctttttg aaggtgtcgc ccttctttta gattgaaagc cgaactggta aaggttacat
    31981 ccttggatga atcctcaaga gccgttaagc taaccaagtt attgtctgca gctgataaat
    32041 catcacgctc cacgctctgc tcgccagtca ctgcttcctt gtcttttagt tttgcgaccg
    32101 tctcaagttc aggagagaca ttttccagcc ccttaatctt gcttacagat gctaggtctg
    32161 acaacttgaa tgtctgacca ttctctatct tcttaataga aaaagatgta ttgagtgatt
    32221 tataaagatt gctttctact gttttgttgg acttcatcag agtcaaacag gctgaaattc
    32281 cggccaataa gaccaataaa atcagaaata aaataaaact tctcagtcgc tttctgctga
    32341 cataagccca agatctttgg attggattca tttgtcacct ccatatttgt aagactatta
    32401 taaaacccaa atatgaaatg tttatgaaat acgaaaaaaa aaa
//
LOCUS       DAVAGB010000023        31177 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVAGB010000023 DAVAGB010000000
VERSION     DAVAGB010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31177
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.023"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            321..2543
                     /locus_tag="VQO19_001166"
     CDS             321..2543
                     /locus_tag="VQO19_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HET1349444.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            2573..3016
                     /locus_tag="VQO19_001167"
     CDS             2573..3016
                     /locus_tag="VQO19_001167"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HET1349445.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(3283..3469)
                     /locus_tag="VQO19_001168"
                     /pseudo
     CDS             complement(3283..3469)
                     /locus_tag="VQO19_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3633..4283)
                     /locus_tag="VQO19_001169"
     CDS             complement(3633..4283)
                     /locus_tag="VQO19_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HET1349446.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            4395..5237
                     /locus_tag="VQO19_001170"
     CDS             4395..5237
                     /locus_tag="VQO19_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET1349447.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            5313..5750
                     /locus_tag="VQO19_001171"
     CDS             5313..5750
                     /locus_tag="VQO19_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HET1349448.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            5819..6121
                     /locus_tag="VQO19_001172"
     CDS             5819..6121
                     /locus_tag="VQO19_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349449.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(6212..7285)
                     /locus_tag="VQO19_001173"
     CDS             complement(6212..7285)
                     /locus_tag="VQO19_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HET1349450.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            7441..8118
                     /locus_tag="VQO19_001174"
     CDS             7441..8118
                     /locus_tag="VQO19_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET1349451.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            8111..9085
                     /locus_tag="VQO19_001175"
     CDS             8111..9085
                     /locus_tag="VQO19_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET1349452.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(9134..11077)
                     /gene="thrS"
                     /locus_tag="VQO19_001176"
     CDS             complement(9134..11077)
                     /gene="thrS"
                     /locus_tag="VQO19_001176"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HET1349453.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(11135..11458)
                     /locus_tag="VQO19_001177"
     CDS             complement(11135..11458)
                     /locus_tag="VQO19_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET1349454.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            12317..12945
                     /locus_tag="VQO19_001178"
                     /pseudo
     CDS             12317..12945
                     /locus_tag="VQO19_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
     gene            13086..13355
                     /gene="rpsO"
                     /locus_tag="VQO19_001179"
     CDS             13086..13355
                     /gene="rpsO"
                     /locus_tag="VQO19_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HET1349455.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            14170..14784
                     /locus_tag="VQO19_001180"
     CDS             14170..14784
                     /locus_tag="VQO19_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HET1349456.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAILGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(15077..15826)
                     /locus_tag="VQO19_001181"
     CDS             complement(15077..15826)
                     /locus_tag="VQO19_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HET1349457.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            15959..18295
                     /locus_tag="VQO19_001182"
     CDS             15959..18295
                     /locus_tag="VQO19_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HET1349458.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            18824..20287
                     /locus_tag="VQO19_001183"
     CDS             18824..20287
                     /locus_tag="VQO19_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET1349459.1"
                     /translation="MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKV
                     INKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKP
                     HSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
                     LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIF
                     ISRNRRSTSIHVVAPSKPTIVDEKIYSVCQKIIQEIEQYFKMKVDAVEIDYLYQYVVS
                     SRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFVDLASHISPLLRRLD
                     NRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEK
                     RARPLKTVVMCTSGVGTSELLRARLEKQFTELDIIDVVAYHQLDELINLYPDLDFIVT
                     TVALQEPASVPFVLVSVFLTEGDKQRLQAKIQEINYE"
     gene            20280..20708
                     /locus_tag="VQO19_001184"
     CDS             20280..20708
                     /locus_tag="VQO19_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET1349460.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKSPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSCIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            20686..21135
                     /locus_tag="VQO19_001185"
     CDS             20686..21135
                     /locus_tag="VQO19_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET1349461.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREAEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            21163..21474
                     /locus_tag="VQO19_001186"
     CDS             21163..21474
                     /locus_tag="VQO19_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HET1349462.1"
                     /translation="MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            21500..22585
                     /locus_tag="VQO19_001187"
     CDS             21500..22585
                     /locus_tag="VQO19_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HET1349463.1"
                     /translation="MLKHLNLKGHLLTAISYVIPIVCGAGFLVAIGLAMGGGVPDALV
                     AGKFTIWDALATMGGKALGLLPVVIATGLSYSIAGKPGIAPGFVVGLIANSVGSGFIG
                     GILGGYIAGFLVQAIIKKVKVPNWIKGLMPTLIIPFVASLVSSLIMIYIIGAPIAAFT
                     NWLTSLLQSLGSASNGLMGAVIGVLSAVDFGGPLNKTVYAFVLTLQAEGVKEPLTALQ
                     LVNTATPVGFGLAYFIAKLLKKNIYTQEEIETLKSAVPMGIVNIVEGVIPIVMNNLVP
                     GLIATGIGGAVGGAVSLTMGADSAVPFGGVLMLPTMTRPVAGICALLANIVVTGLVYA
                     ILKKPIKHTEPVMTVEEEIDLSDIEIL"
     gene            22596..23291
                     /locus_tag="VQO19_001188"
     CDS             22596..23291
                     /locus_tag="VQO19_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET1349464.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKVTIMTVDPGFAGQRFLKSTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            23328..25298
                     /gene="tkt"
                     /locus_tag="VQO19_001189"
     CDS             23328..25298
                     /gene="tkt"
                     /locus_tag="VQO19_001189"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET1349465.1"
                     /translation="MSLQSVNAIRFLGVDAINKSNSGHPGIVMGAAPMAYSLFTKHLR
                     ITPEQPNWINRDRFILSAGHGSMLLYALLHLTGYKDVSMDEIKNFRQWGSKTPGHPEV
                     THTSGVDATSGPLGQGISTAVGFAQAERFLAAKYNKDGFPIFDHYTYVIAGDGDFMEG
                     VSAEAASYAGHQALDKLIVLYDSNDICLDGETKDTFSENVRARYDAYGWHTVLVEDGT
                     DLAAISTAIETAKFSGKPSLIEVKTVIGYGSPNKSGTNAVHGAPLGAEETGATRKFLG
                     WDYDPFEVPEEVYSDFKTNVADRGQEAYDAWASLVSDYKVAYPEVASEIDAIVAGKSP
                     VTITEKDFPVYENGFSQATRNSSQDAINTAAAVLPTFLGGSADLAHSNMTYIKADGLQ
                     DKYNPLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAIRLSAIQEL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRSMPNLTVIRPADARETQAAWHHALTSTT
                     TPTVIVLTRQNLVVEEGTDFGKVAKGAYVVYDTPGFDTIIIATGSEVNLAIKAAKELV
                     LQGGKVRVVSMPSTELFDAQDATYKEDILPSKTRRRVAIEMAATQSWYKYVGLDGAVI
                     GIDIFGASAPAQTVIDNYGFTVENIVAQVKSL"
     gene            25671..26931
                     /locus_tag="VQO19_001190"
                     /pseudo
     CDS             25671..26931
                     /locus_tag="VQO19_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(27006..27536)
                     /locus_tag="VQO19_001191"
     CDS             complement(27006..27536)
                     /locus_tag="VQO19_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HET1349466.1"
                     /translation="MLDEKRKNYVEDKRQNFPSLPSWKMDLFSEEEKRIYFQTTCEVS
                     SKDSAINKYKIEKIIKISNKGNVYRAIRKSDEQKVIIKQSRPFVNYDAEGEWTALDDI
                     KNEAYMLKKLADKSYTTNLTDEFYIVDDYFLVQEQVDGLNFEEFIRETEHSLNIREKT
                     LDNIVNIVSDIHKLGI"
     gene            complement(27530..27997)
                     /locus_tag="VQO19_001192"
     CDS             complement(27530..27997)
                     /locus_tag="VQO19_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349467.1"
                     /translation="MDLLEKECLKCDKNFQQGDIWNYYYLSDKVPAQGWKIHISSQIK
                     DAVNIFKIVYKLSQLNNCSFKVVKNLEELKKINSPREMSPTANKFITLYPKSESEAKS
                     MICNLTNKLSEFKAPKILSDYQCGMHSPVHYRYGAFLKKQAYDEKIKKSSIYC"
     gene            28537..29214
                     /locus_tag="VQO19_001193"
     CDS             28537..29214
                     /locus_tag="VQO19_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HET1349468.1"
                     /translation="MISKRLELVASFVPQGAILLDVGSDHAYLPIELVERGKIESAIA
                     GEVVEGPYQSAVKNVEAHGLEEKIQVRLANGLAAFEEEDRVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            29201..29998
                     /locus_tag="VQO19_001194"
     CDS             29201..29998
                     /locus_tag="VQO19_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HET1349469.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLEIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            30015..31118
                     /locus_tag="VQO19_001195"
     CDS             30015..31118
                     /locus_tag="VQO19_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HET1349470.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYAVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
BASE COUNT         9152 a         5622 c         6967 g         9436 t
ORIGIN      
        1 gtttgctctt tgattttcat tgagtattaa ttccaaaatc cagtcaaggt accagtgtat
       61 gtgatacgag ttccaccgtt tatctttcgt atcttcaatg gaattgggga aatcagaaag
      121 tctttgggtt acaatatggt ttccgttctt ctatctctcc ttctatcacc taagtttaaa
      181 atctaacttc gtagtatatt atgggccaat aattcagaat tatcaagcaa ttttgaatta
      241 tttttttctt attctgttcc aatctagttt tcatattctt aaaaaagtga taaaatggta
      301 ggaagaattg gagagtagag atgccgaaag aagtgaattt aacaggcgaa gaagttgtcg
      361 ctttaaccaa agaatattta acggaagagg atgttcattt tgtccataag gccttggtct
      421 atgctgttga atgccacagt ggtcaatatc gcaaatcagg cgagccttat atcattcacc
      481 ctatccaagt ggcaggtatt ttagctaagc taaagctgga tgctgtaaca gtagcttgtg
      541 gattcttgca tgatgtggtg gaagatacag atgcgacctt ggacgatttg gaaagagagt
      601 ttggtcctga tgtgcgggtg attgttgacg gagttaccaa gcttggcaag gtcgagtaca
      661 aatcgatcga ggagcaatta gcggaaaatc atcgcaagat gctcatggcc atgtctgagg
      721 acatccgcgt tattttggtc aaactgtctg accgcttgca caatatgcgg accctgaaac
      781 atcttcgaaa agacaagcag gagcgtattt ccaaagaaac catggaaatc tatgccccac
      841 ttgcccatcg tttggggatt tccagtgtca aatgggaatt agaagacttg tctttccgtt
      901 atctcaatcc aacggagttt tacaagatta cccatatgat gaaggaaaag cgcagggagc
      961 gtgaggcctt ggtggatgag gtagtcacaa aattagagga gtatacgaca gaacgtcact
     1021 tgaaagggaa gatttatggt cgtcccaagc atatttactc aattttccgc aaaatgcagg
     1081 acaagagaaa acggtttgag gaaatctatg atctgattgc tattcgttgt attttagata
     1141 cccaaagtga tgtttatgcc atgcttggtt acgtgcatga attttggaaa ccgatgccag
     1201 gtcgcttcaa agactatatt gccaaccgca aggccaatgg ttatcagtct atccatacga
     1261 ctgtttatgg accaaaaggg ccgattgaat tccagattcg aaccaaggaa atgcacgagg
     1321 tggctgagta cggggttgcg gctcactggg cttataagaa aggtataaag gggcaagtta
     1381 acagcaagga atcagctatt ggaatgaact ggatcaagga gatgatggag ctccaagacc
     1441 aggctgatga tgctaaggaa tttgtggact ctgttaagga aaactatttg gctgaggaga
     1501 tttacgtttt taccccagat ggagctgtcc gttcccttcc caaagattca ggaccgattg
     1561 attttgccta cgaaatccat accaaggtcg gtgaaaaagc aactggtgcc aaggtcaatg
     1621 gccgcatggt tccactgaca accaagttaa agacagggga tcaggttgaa attatcgcca
     1681 acccgaactc ctttggacct agccgtgact ggctcaatat ggtcaagact agcaaggcgc
     1741 gcaataagat tcgccagttc tttaaaaacc aagataagga attgtctgtc aacaagggtc
     1801 gtgagatgct gatggctcag ttccaagaaa atggctatgt ggcaaataaa tttatggaca
     1861 agcgccacat ggatcaagtt ctgcaaaaga ccagttacaa gacagaagac tccctctttg
     1921 cggccattgg ttttggggaa atcggtgcga ttaccgtctt taatcgtctg actgaaaagg
     1981 aacgccgtga ggaagagcgt gccaaggcca aggctgaggc agaggagctt gtcaaaggtg
     2041 gcgaggtcaa ggttgaaaat aaagaaactc tcaaggtcaa gcatgagggg ggagtggtta
     2101 ttgaaggtgc ttctggtctc ctagtgcgga ttgctaagtg ttgtaacccc gtgcctggtg
     2161 acgatattgt tggctacatt accaagggtc gtggtgtggc tattcaccgt gtggactgta
     2221 tgaacctgcg tgcccaagaa aactacgagc aacgtctcct tgatgtggaa tgggaagacc
     2281 agtactctag ctcaaataag gagtatatgg cccatatcga tatctacggt ctcaaccgta
     2341 caggactgtt gaacgatgta ctgcaagttc tttcaaatac aaccaagaat atttcaacgg
     2401 tcaatgccca accaaccaag gatatgaagt ttgctaatat ccatgtgtcc ttcggtattg
     2461 ccaacctctc tacactgacc acggttgtcg ataaaattaa gagtgtgcca gaagtttact
     2521 ctgtcaaacg gaccaacggc tagttgtcct agctcttact agaaaggcta ttatgaaaat
     2581 cattatccaa cgggttaaaa aagcccaagt gagtatagaa ggccagattc agggaaaaat
     2641 caatcaggga cttttattgc tggttggtgt tggaccagag gaccaagagg aagatttgga
     2701 ctatgctgtg agaaaactgg tcaatatgcg gattttttca gacgcagaag gcaagatgaa
     2761 cctgtctgtc aaagatattg aaggagaaat cctctctatt tctcagttta ccctctttgc
     2821 ggatactaag aaaggcaatc gtccagcctt tacaggggca gctaaacctg atatggcatc
     2881 agacttctat gatgctttca atcaaaaatt agcgcaagaa gtgcccgttc agacaggcat
     2941 ctttggagca gatatgcagg ttgaactggt taataacgga cctgttacca ttatcctaga
     3001 tactaaaaag agataagaaa gaccaagccc agtcggcttg gtctttctca tcgatcataa
     3061 aatactccaa aaagaaatcg gttcttgata tgcttggggg aagtctcttt tcaggctttg
     3121 gcagatgcga taggaaggga tgagatatcc taggatgagg agagttccct gaaggaaaag
     3181 tggaatatca cttaaagaca ccaaggagag aatcatcagg ctatcccata ggagaatttg
     3241 taaagcaaaa cgccagaatc tcggtctaat ctgggaatag agttaactaa agtggtcaca
     3301 aagttggttt gaaagatagg tcaatagcac aggatgaaag aaaatgagcc aaccactata
     3361 aatcaaaatc cagtcccaag taagcccccc ttttaaatgt caaaaatgcc agcatgattc
     3421 catcaatgac aaggagttga atggttttga tgaagatgat ttttttcatg ctaaaacctc
     3481 cttttttcat ctgttagtga cgtaatgctt tatataatta ttatacagta ttcagtcggg
     3541 atatgaaaac gtttactatc gtttttgata taaaaaatag ataagaaaac cctgaaaata
     3601 aaactttcag ggttggtagg ggacttgaga aattagttga ttttctcgac atagagttgt
     3661 tttgcaatgt ccatattcac ttgtaaatcc tcgtcgttac tgaggatagt gaaggtattg
     3721 ctgaagccat caaactgctt gacttggagc tggtcaccga tgtgaagtga gtgcttgtcc
     3781 agataatgga gaatgtcaaa actatcgtgc acccgagtca ggcggtaggc gccagcttcc
     3841 ttgatatcag ctagtgggag gttattgatt tcaacgagga gttctccctt ggcaggaata
     3901 gttcctccgt gggggcaggt tttagggaaa cctagcagtt tatctagtct ttccacgaac
     3961 aggtcagaga cagtgtgttc caagacctca gcttcctcgt gaatctggtc acttgtatag
     4021 tctaaatgat gaactagaaa aacttcaatc aagcggtgct tacgatagag ctcagagacc
     4081 agtttgagac cgaggtcagt cagtagatag ccacattcct tgtcctttag gatgagattt
     4141 tcacttttca ttcgtttgat catttcagtt acggcagggg gagagacttg catgcgagcc
     4201 gcaatttcct tgttggtaat cttatgcagg tctatgccaa tttcataaat acattttaga
     4261 tagtcttctt tgtttggggt cattcgtttc ctcttgtcta atatctttat ctagtatatc
     4321 aaaaaaagct agatttctct agctgtgact ttttatgtta tacttattgc aagagaaaaa
     4381 acgaggagat ggatatgacg aaaatagctc ttctttcaga tattcatgga aataccaccg
     4441 ccttggaggc tgttttggca gatgctcagc agctaggagt ggatgaatac tggcttttgg
     4501 gagatattct catgccaggg acaggacgta gaaggatttt ggacttgttg gatcaactac
     4561 cgattacggc tagagttttg ggaaactggg aagacagtct ttggcatggt gtccgtaagg
     4621 aattggatag tactcgccct agtcaacgct atctcttgcg ccagtgccag tatgttttag
     4681 aggaaatttc cctagaagaa attgaagtgc tccacaatca acctcttcaa attcatcgtc
     4741 agtttgggga tttgacggtg ggaattagcc atcatctgcc tgataagaac tgggggcgag
     4801 agttgattca tactggcaaa caagaggagt ttgaccgctt ggtgactcat cctccctgtg
     4861 atattgctgt ttatggacat attcaccagc agttgcttcg ttacgggact ggtgggcaat
     4921 tgattgtcaa tccgggttcg attggccaac ctttcttttt ggacgctcag ctacggaagg
     4981 acttgcgggc ccagtatatg attttggagt ttgatgacaa gggcctggta gatatggact
     5041 tccgacgggt agattacgat gtggcagctg aattgcagct ggctaaagac ctgagacttc
     5101 cctattttga ggtttactat gaaagtctgg tcaatgggat ccaccatact catcatcagg
     5161 aatttttgag agaattggct cagaaagagg gttgcgatcg ggagttagac gactggttga
     5221 aaagtggtaa cgattgacat tacaactaaa aagggtataa taatagaaaa agaagagtag
     5281 aggcagggta gcctcgtaaa aaggagaaga ggatgcaaat tccaagtaga tttaccattg
     5341 caactcatat gctgataatc attgccctcg aggggaagga aagcaaggtg accagtgatt
     5401 ttctggctgc tagtgttggg gtcaatcctg tcattatcag aaagatcttg tcccagttga
     5461 agaaggcaga gctgatttca gtagcgcgtg gaacgggcgg aacagagatt gtcaaggacc
     5521 ttaaggatat tagtctttta gatgtttatc aggcggtcga atgtcttggt aagacaggtc
     5581 aactcttcag tttccatgac aatccgaatc caaattgccc tgtaggagct catattcatg
     5641 atgttttgga tcaaaaattg gagagaattc agttgactat ggaggcagaa cttggtcaga
     5701 ccagtctaga aaaagtcgtg gccgatgcag agagtcagat gaaggattaa gagggataaa
     5761 tgccctcttt ttttctttgg ataattatga taaaatgtag ctattaaagg agtaagaaat
     5821 gtatctcgtt atagaaattg tattagcctt tatagtgtca ttttggaagg ataatagaag
     5881 tttgtggaat ccagtattat ttttattatc cctcatttca agttattttt atctatccta
     5941 ccttttttat aaaaatggat acgagaatgt tcagttagct ttttatgtat ttgcctttgt
     6001 cttacttcct tttttgcttt ttctaagtgg catcttttta atctataatg gggtcatttt
     6061 gttgaaacga gagggacgtt ccaagcccca ttatctctca atgctctttg atttttattg
     6121 actattagat tctatttaaa aagacttaga atgcacatga aagtatgtat tctaggtctt
     6181 ttgttttgta tacatttaat tttcaagagt attatctatt tttccatgca tggtaacgag
     6241 tatcaatcaa taactgggta aggcgaccca aggtttctct ttcttctgga gtgagggatt
     6301 gagcttggac aaagagatga tgaatgtatt caagcgcctt taaggaagcc aagtcattga
     6361 tagagctaat accagcatca agaatagtgc caaagaagag gtcgaagtag agctgaagtt
     6421 cttcgtcagg gactgtggcc acccattctt taaaggttgt gtctacttgc cggctatcac
     6481 tgttggtctt atccagttga acgaagtgct tgtcctcaat ctgccaacta aaggtatcgt
     6541 gctgggcgat gccacccagg gcagtactct gaacgatgat ttggtgagca ggaatttcca
     6601 gcatcatacc gataatggaa ccttgtggaa tgaatatctt gcttctatcc attatccttt
     6661 gataacccgc agtctgtgtc aattcttgat ggagaccagg tgcatcaaat gtataaactg
     6721 ctgtgatctg attttgcaaa ctttgctcaa tttggctagc agcatagata gcgagatttc
     6781 ctcccttgga atgcccagcc agaataacct tttgcttagg atgatgggca aaaaagttct
     6841 ttaaatagcg aagggcgtgc ttttgagcag gaatttcctt catataggtc aggtggaaat
     6901 cttccttcca gccaatgata ctgtcatctg tcccacgaaa gacaatcaga taggtatcga
     6961 ggctgacacg ataagtcata gccgcaaatt gcttttgcag ttcagggtcg atgtcgttga
     7021 taaaatggga gagtttgcaa tttttgaagc gcttgtgttg agccaattca tctaataatt
     7081 gaaggcgatt tttgctagta agcatggtgg gctctcttgg aacctgaggt gctagatcta
     7141 aaagacgttg aggaagtgtg gagaccagat tatcaaagga gaggtaggtg atttctatta
     7201 aggttagaat gtctaactca ttcaagggaa ggtcgtaata agaatcatat gcgacatctt
     7261 tcagatagtc aaaaatattg gccataagag ctcctttctt tttatttatc ttagcaaatt
     7321 tccctcaaat tagctagtag catagcctgt ttgtactggc taaaaacagg ctatttcaaa
     7381 ttcagtttca gaccatctag catggaaaaa tctgttataa taatggaaaa ggagaagcgc
     7441 atgcacaaga ttttattaat agaagatgat caggtcattc gtcaacagat tgggaaaatg
     7501 ctctctgaat ggggatttga agtggtcctg gtagaagact ttatggaagt tttgagtcta
     7561 tttgttcagt cggaacctca tctggtcctc atggatattg gtttgccctt gtttaatggt
     7621 tatcactggt gtcaggaaat ccgcaagatt tccaaggtac ctatcatgtt tctttcttcg
     7681 agagaccagg ctatggatat tgttatggca atcaatatgg gggcggatga ctttgtgacc
     7741 aagccttttg accagcaggt tcttttagct aaggttcagg gcttgttgcg tcgttcctat
     7801 gagtttgggc gtgatgagag tttgctggaa tatgctggtg ttatcctcaa taccaaatcc
     7861 atggatttac attatcaagg gcaagtcttg aatttgacca agaatgaatt ccagatttta
     7921 cgcgtgttat ttgagcatgc aggcaacatc gtagcacgtg acgacctgat gcgggaactt
     7981 tggaacagtg actttttcat tgatgataat accctctctg tcaatgtggc tcgtttgcgt
     8041 aaaaagttgg aggagcaggg attggtagga tttatcgaga ccaagaaagg aatagggtac
     8101 ggattgaagc atgcttgatt ggaaacaatt ttttctagcc tatctgcgct cccgtagtcg
     8161 tctttttatc tatctgcttt ctttggcatt tcttgtctta ctctttcagt ttttatttgc
     8221 cagtctagga atttacttcc tctacttttt cttcttgtgt tgctttgtaa ccatattatt
     8281 tttcacttgg gacatattgg tggaaacgca ggtctatcgc caggaacttc tctatggaga
     8341 gagggaagcc aagtctcctt tggaaatagc tttagcagaa aaattagaag cgcgtgagat
     8401 ggaactctat cagcagaggt caaaagcaga aagaaaactg acggatttgc tggattacta
     8461 taccttgtgg gtccatcaga taaagacccc cattgcagcc agtcaactct tagttgcaga
     8521 agtggtcgac cgccaactga agcagcaact agaacaggaa attttcaaaa tcgactccta
     8581 taccaaccta gttttacagt acctgcgttt agaaagtttc catgatgatt tggtcttaaa
     8641 gcaggttcaa attgaggact tggtcaagga aataattcgt aaatatgctc ttttctttat
     8701 tcaaaaaggc ttaaatgtca atctacatga ccttgataaa gaaatcgtga cggataaaaa
     8761 gtggctgcta gtggttattg agcaaatcat ctcaaacagt ctcaagtaca ccaaggaagg
     8821 tggtctggag atttatatgg atgaccaaga gctttgtatc aaagatacgg gaatcgggat
     8881 aaaaaacagt gatgtcctcc gagtatttga acgtggcttt tcaggataca atggccgttt
     8941 gacccagcag tcctctggac ttggccttta tctatctaag aaaatttctg aagaactggg
     9001 gcaccagatt cgtatcgagt ctgaggtcgg aaaaggaacg acagtgcgga ttcagtttgc
     9061 tcaagtgaac ttagtccttg agtaaaaata gatgagaaaa agcctccaga ttggaggctt
     9121 ttatgctaga ctcttatttc tcaacgcgtg atttgttggc gatatcagct aggatagctt
     9181 gaacaaaatt atcaactgag acagtttgtg tttctttttg gccgtagcga cgaacgttga
     9241 ctgtttcgtc ttccatttct ttgtctccaa caattaattg gtaaggaatc ttgctggttt
     9301 gtgaagcacg aatcttgaac tgcatttttt cattgcgctc atctacgtct gcacggacac
     9361 cgcggtcacg gagtttcttg gccacttccc aagcgtagtc cacgtgtttt tcgttagata
     9421 ctgggatgag ggttacttgg tgtggtgcca gccatgttgg gaaggccccc ttgtagttct
     9481 caatcaagat agctgtgaag cgttccatag ttgagataac cccacggtgg atcatgactg
     9541 gacggtgatc ttcgccatca gctccgatgt atttgaggtc gaagcgttct ggcaacaaga
     9601 aatcaagttg gatagtagaa agggtttctt cttttccaag ggcagtttta atctggatat
     9661 ccaattttgg tccgtagaag gctgcttcac cttcggcttc aaagtagtcc acgcccattt
     9721 catcaagagc tgcacgaagc atggtttggg cattttccca catctcatcg ttatcaaagt
     9781 acttatgagt atcttgaggg tcacgaagag agaggcggaa gcggtagtca gtcaagttga
     9841 agtcttcata aacatcgata atcaactgaa gggcacgttg gaattcttct tggatttgtt
     9901 ctggagtaac gaataggtga ccgtcgttga gtgacatttc acgtacacgt tgaaggccag
     9961 tgagggcacc agatttttcg taacggtgca tcataccgat ttcagcgata cggattggca
    10021 attcacggta agagtgaaca tggtgtttga aaacttggat gtggtgcgga cagttcattg
    10081 gacgaaggac aaattcttcc ccgtcaccca tgtccatggt tgggaacatg tcttcttggt
    10141 aatgatccca gtgaccagaa gtcttgtaaa gctcaacaga agcaagtggt ggagtgtaga
    10201 cgtgttggta gccagaagcc aactctttgt ttacgatgta gcgttccaat tcacgacgga
    10261 tagtcgcacc atttggcaac cagaatggca aaccttgtcc cacttcttgt gaaatcataa
    10321 agaggtcaag ctctttacca agtttacggt ggtcacgttc cttagcttct tcacgcattt
    10381 gaaggtagtt tttcaagtct ttcttgtcaa accaagctgt accgtagata cgttgcatca
    10441 tagcgttgtc gctgtttcca cgccagtacg caccagctac atggagaagg tggaagattt
    10501 ggatacgacc tgttgatgga acgtgaggtc cacggcagag gtctacatat tcaccctgac
    10561 gatagatagt caaaccgcct tcgtcttctg agtgttcttc aatcaattcc aacttgtaag
    10621 ggtcattttt gaagatttca cgtgcctcgt ctttagtcac ttcttcacga atagatggga
    10681 agttttcttt gacgattttt tgcatttctt cttcgatacg aggaaggtct tcgttagaga
    10741 tttgaccagc tgtgttgtca gtatcgtagt agaaaccatc ttcgatggct ggaccaactc
    10801 ccaagtgaat gtctgggaaa agacgacgag ctgcttgggc gaacaagtga gctgctgagt
    10861 gacgcaagat tggaagggca tcttcgtgat caggtgtcac aatttcgatg cttccatctt
    10921 cagtgatagc gcgagtagtg tcgatgagtt tgccgttgaa tttaccagcc aaggcttttt
    10981 tagctaggga attgctgata gattgggcaa tttcaaaagt tgttacgcca gattcgaatt
    11041 cacgaacagc gccatctggg aaagtaatgt taatcatgat gttctccttt tttattattt
    11101 catagtttct aagcattgat tttttatcag cagactactt ccaagtccta acgttcaatt
    11161 gcttttcttt atcagagagg aagttttcca tttccgtcag aatgtctata tccaaacgtt
    11221 gagaaagttc taatagccac cagatatttt ctgaaagttt ttgttccagt gtgtagggtg
    11281 tttcatcata gtagcgtcct tgctttgtca tcaccagtcg ttggaaattt ccaatatcat
    11341 tagataaagc caagaggtct tcttctaccg tccacttgaa atcatgatgc ttaacttcca
    11401 gttcgtgata agcttgtcgg attgcccaac tgcgctccac taattcttgc aactccataa
    11461 ttagtatcct aataaaaaaa tgcgacatcc tcgaaaggac gtcgcaacgt ggttccacct
    11521 tcatttatgt acctcaaaag agagggacac ctctgatcgg ctctaacgtg gccaccgttt
    11581 tatgttttca taaaaaactc aagagtagta tcagtttaga cttcctatgc gtttccagca
    11641 accacgcact ctctagtaga aagggactaa gtgacttgtc tctatggatt attatagcat
    11701 gattgtgaga tttttcaagg attttgtgaa agttttttgt ttttcatatt ttgtagaata
    11761 tgcttgatgc taataccaga atccatgccc accagagcaa ctgtttcata gattagcaag
    11821 taaattagta taaactcacc aaaggttatg atagtaaagt aaaagagcag tccgttacca
    11881 actaaccatc aaagtgagaa acggaaacgg tagctataga gtaacgatac aatcaagatt
    11941 accagaggtg taaagaagag aagattgttt atatagtgta aaggggtcag aaacaactag
    12001 caagaacaac tcataaagtg gctaataaaa gaataatatg accagatagt aggggagatg
    12061 ggaatagaat ctacgcatga taatcacctc gttttaaaaa aacagacaac ttagatctct
    12121 tgctatgatt attatagcat gtttaaaaca agaaagtaaa tttgttgaca aagaagattt
    12181 ttcttttcac tagaatcata gttagttttc ttggtagaaa tattttgata ataattaagc
    12241 aagactattg atattgatta ttaagagtgt cacatttgtt gtaactaaaa taattacaac
    12301 aatagaggta taaaaaatga aactagcagt tattgcagca aatggacaag cggggaaagc
    12361 aattgttgaa gaagcagtca aacgaggaca tgaagtaacg gctattgttc gttctgaaaa
    12421 caaaagtcaa gctgagtcta ttattaaaaa agatttattt gagttgacaa aagatgatct
    12481 tactggattt gatgctgtta tttcagcgtt tggtgcttat acaccagata cgctaccgct
    12541 ccacagcaaa tcaatcgaac tatttaatca gcttcttgct ggaacacaga cacgttttct
    12601 agttgtaggg gagcagaaag tctttatata gatgaaacaa aaacgacacg acttttagat
    12661 acgtctgatt ttcctgaaga atttaagtca ctagcaaaag ctcaagcgga tgaattggat
    12721 cttcttcgta caaaaaataa tctcaactgg acttttgtca gtcctgctgt agattttatt
    12781 cccgatggtg aaaaaacagg aaactacatt ctagcaggag aaatttttac tactaatgaa
    12841 aaaggaataa gccagattag ttatgcagat tatgctattg gattggtaga tgaacttgaa
    12901 aaaggtcatc atataaaaga acgtatctct ttacttgaaa aataataact atgagagtat
    12961 taatgtttga cagaaaattt aaatcttggt aaaataggga ttgtcgtaaa gacaaataac
    13021 ttcttcttgg ttacaggcat gccaacctgt cactcggatg aagccaaata aaaaggagaa
    13081 acatcatggc aatctcaaaa gagaaaaaaa atgaaatcat tgcacaatat gcacgtcacg
    13141 aaggtgatac aggttcagta gaggttcaag ttgctgtcct tacttgggaa atcaaccacc
    13201 ttaacgaaca catcaaacaa cacaaaaaag accacgctac ttaccgtgga ttgatgaaaa
    13261 aaatcggtcg ccgtcgtaac ttgcttgcat acttgcgtaa aaacgacgtt aaccgttacc
    13321 gtgagttgat caactctcta ggacttcgtc gctaattcaa gatacaaatg ctgtcaaaag
    13381 cacaaagcaa aaataggaaa attgacgaag aaacttcagt ttctaggaga ttttatcttt
    13441 tttgccaagt gcttaggccg tgttcaattg agcatatctt gataatgaag ctactctaaa
    13501 ttgggtagct tttttgcgtt gtcaccttac ctcgatatac tcaagtataa tctttggtta
    13561 cggttcctag cactgtaagg taaaataaac cagcttttct cccttcgggg agattttttt
    13621 tgtttcactg aaagtttcgt acgatcttcg cctcgtcgcc tagtctataa acgatttatc
    13681 cagcaagaat catgatgcta agggcgtcaa aaatccgtat gaaaataggg aaatggcaca
    13741 gtgttcgatg aacgcaagga gtttcatctt tttcactagg attttagtcc gggctcaaat
    13801 cagctctctg acttcagagg gcttttttat tgaggtttta tcggtcacaa ttttggagac
    13861 tacaaaaacc tcaaatggta tcagctaatt acaccataaa ggtgcgcagt tactcggctt
    13921 ttcaagccga gtagctgtat gcaagccccc tagaagagcc cactctttac aaagtaaagt
    13981 atagtatgtt atactttaca tggaagtagt cactgaattc cagttagaaa ttactttgta
    14041 actacgtttt gaggaggagt aaaatgcttt cctacgttcg acattaccca ctagcgatag
    14101 ctaaattaat gtgtctgtgc tctcctaaaa tctgctgatt tattactgac taatacagga
    14161 ggttttttta tgggacagac aatcatatct gctattggtg tttatatttc caccagtatc
    14221 gattatttaa ttattttaat tattttattt gcacaactat cacagaataa acagaaatgg
    14281 catatttatg cggggcaata tctaggcaca ggcttacttg taggggcgag tttagttgct
    14341 gcttatgtcg ttaatttcgt gcctgaagaa tggatggttg gattgcttgg tttaatccct
    14401 atctatttag ggattcgctt tgcaattctt ggagaagatg cggaagaaga agaggaagaa
    14461 attattgaaa gattggaaca aagcaaggca aatcaactgt tttggacagt tacattgctg
    14521 acaattgcgt ctggcggaga taatttaggt atctatatac cttattttgc ttcgttagat
    14581 tggtcacaga ccctcgtggc cttgcttgtg tttgtaatcg gcataattat cttttgcgag
    14641 attagtcggg tgttatcctc tattccgtta atattcgaga caattgaaaa atacgagcga
    14701 atcattgtgc cattagtatt cattctactt ggactataca tcatgtatga aaatggcacg
    14761 atagagactt ttctgatcgt gtagattttt ttgtttcact aggattttag cccgagctca
    14821 aatcagctct ctgattttca gagggctttt tcattgagta taaatggaca atcttaaagt
    14881 tactctattg tagagtggct tttgatttga ttaggagatt cttataaata tagtaaaatg
    14941 aaacaaaaac aggacaaatc gatcgtgaca gtcaaatcga tttctaaaaa tgttttaaga
    15001 agtagaggtg tactattcta gtttcaattt gatatataaa tgaaaacctt agctgtttgg
    15061 ccaaggttca tttcttctat gcaagttctt ctcttttctt atctgggttc cagatgaagc
    15121 ttgcgataaa gctaaagatg atggttagga tagcgaggat aatagcaagg atgagggcag
    15181 ggatgcggat aaaccaccag agtggatttg gttttttatc attgtgccat tgtttcgttt
    15241 cttcgtccag acgttggaat tctgtttgaa tacgattggc gactgtttca atgccttcat
    15301 cattcatttt cttgatatct gagatatcga ttggatttcc aaagttcata tcgacacgtt
    15361 cacggctaat caagcccttc aaagtcatgg gaccggtgta ggtaaccggc atgatacgga
    15421 ccttggccat tttggcaatc agtgctgcgc cccccttgac atcgtttgag tggcggctac
    15481 cacttggaaa catgatgaga gagcggtcac tttttttgag aacgttgata ggatatttga
    15541 tggctgaggc gctgggattt tcacggtcga tgggaaaggc gccacacata cgaatccacc
    15601 aaccaaagat acggttggta aagagttctt tttttgccat aaagatgaac tgttttggct
    15661 tggtcgcaaa ggccatataa acaggatccc accaggtacg gtgaggcgca actaaaatat
    15721 aattttcatc ttgattagga attttatcag tattatgata gtgagcattg ccattgatgg
    15781 accataagag caatacaact aatccacgca aataagtata aaacatgcga tctccttcga
    15841 ttgttttctt gttattatta taccttatca aaggagggct ggcaaacttt tcccttgact
    15901 agatgcatat ttgggatgaa attagaattc tgttaaaaaa aatgatataa tagaatttat
    15961 ggataaaaat aagattatgg gattaaccca aagagaagtc aaggaaagac aggctgaggg
    16021 tttggtcaat gactttaccg catcagccag taccagcact tggcaaatcg ttaaacgaaa
    16081 tgtctttacc ctttttaacg ctttgaactt tgccattgct ttggcccttg cctttgtgca
    16141 ggcttggagc aatctggtct tctttgctgt tatctgcttt aacgcttttt ctgggattgt
    16201 gaccgagcta cgagccaaac acatggtgga caagctcaat ctcatgacca aggaaaaggt
    16261 caaaaccatc cgtgatggtc aggaagttgc tcttaatcct gaagaattag tgctaggaga
    16321 tgtcattcgt ttgtctgcag gagagcagat tcctagtgat gccttggttt tggaaggctt
    16381 tgcggaagtc aatgaagcca tgttaacggg agaaagtgat ttggtgcaaa aggaagttga
    16441 cggcttactt ttgtcaggaa gtttcctagc cagtgggtca gttttatctc aagttcacca
    16501 tgtcggtgca gacaactatg ctgccaaact catgcttgag gctaagaccg ttaaacccat
    16561 caactcccgt atcatgaaat cgctggacaa gttggctggt tttactggga agattatcat
    16621 tccctttggt ctggctctct tgctggaagc cttgctttta aaaggcctgc ctctcaagtc
    16681 atccgttgta aactcgtcga cagctctttt gggaatgttg cctaagggaa ttgccctttt
    16741 gaccattact tcgctcttga ctgcagtgat taagttgggc ttgaaaaagg tcttggtgca
    16801 ggagatgtac tctgttgaga ccttggcgcg cgtggatatg ctctgtctgg acaagacggg
    16861 caccatcacc caaggaaaga tgcaggtgga ggctgttctt ccactgacgg aaacttacgg
    16921 tgaagaggct attgccagca tcttgactag ctacatggcc catagtgagg ataagaatcc
    16981 aactgcccaa gccattcgcc agcgttttgt gggagatgtt gcttatccta tgatttccaa
    17041 tcttcccttc tcgagcgacc gcaagtgggg ggctatggag ttagaaggct tggggacagt
    17101 tttcttaggg gcacctgaga tgttgctgga ttctgaagtc ccagaagcca gggaggcctt
    17161 ggagagagga tcacgtgtct tggtcttagc tctcagtcag gagaaattag accatcacaa
    17221 accacagaaa ccatctgata ttcaggctct agccttgctg gaaatcttgg atcctattcg
    17281 agagggagcg gcagagacgc tgaactatct ccgttctcag gaagtggggc tcaagattat
    17341 ctctggtgac aatccagtta cggtatccag cattgcccag aaggctggtt ttgcggacta
    17401 tcacagctat gtcgattgtt caaaaatcac ggatgaggaa ttgattgctc tggcggagga
    17461 gacagcgatt ttcggacgtg tttcccctca tcaaaagaaa ctcattatcc aaacgctgaa
    17521 aaaagcgggt catacaacag ctatgactgg ggatggagtt aatgatatcc tggctcttcg
    17581 tgaggcggat tgttctatcg taatggcgga gggagacccg gcaacccgtc agattgccaa
    17641 cctggttctc ttgaactcag actttaatga tgttcctgag attctttttg aaggtcgtcg
    17701 tgtggtcaat aacattgccc acatcgctcc gattttcttg ataaagacca tctattcctt
    17761 cctgttagca gtcatctgta ttgccagtgc tttactaggt cggtcagagt ggattttgat
    17821 tttccccttc attccgatcc agattaccat gattgaccag tttgtggaag gtttcccacc
    17881 atttgttctg acttttgagc gaaatatcaa acctgttgag ccaaatttcc tcagaaaatc
    17941 catgcttcgt gccctaccaa gtgccctcat ggtcgtgttt agcgttcttt ttgtgaaaat
    18001 ctttggaacg agtcaaggtt ggtctgagtt agaaatctca actctcctct attatctctt
    18061 ggggtcaatt ggtttcttat ccgtatttag agcctgcatg ccattcactc tatggcgagt
    18121 cctcttgatt gtctggtcag taggaggctt cctagccaca gctctcttcc caagaatcca
    18181 aaaactgctt gaaatttcaa ccttgacaga acaaacgttg cctgtttatg gtgtcatgat
    18241 gttggtcttt acagtgattt tcatcctgac tagtcgctat caagctagaa aataaagaaa
    18301 gactgcaatc tgtggattgc agttttttat acgatggatc tatcgtagat ctgatgtgca
    18361 aggcctacgt gtctattatc tatcggtgaa cccaagagtg attctcaagc ctgcttggat
    18421 tgaggtaata gattcaaata tctgtagtta gactatttga agtttgatgt aagaaagaga
    18481 aagcgacaga ttgaagtaat tttaactctc ttctattgct agaacaaatg gtcggatagg
    18541 ttggtagttt gaaaatgaag atgcaatcta ttgttaaatg gaacatagtg ttatttatta
    18601 gaaaatcgtt tggtttattt cttatcaaat acgaaaagca acttaaatat ttcaactaaa
    18661 atagatgtta tgaagaaaag gtaaaatgat tttggtatag tgaggttctg ttctatttga
    18721 tatcatattt ttgataaaaa caaaaatgtc cattgcaaag gacaaaatgc gaagtatatt
    18781 attttttgaa agcgatataa tggaatcata aaggaggtgt atcgtgtcta gaaaacaaga
    18841 acaaatggaa acgttgttgc tccttttgcg agatagtaag gattatatat ctgctaaagt
    18901 attgggagaa aaattaaatt gctctgataa aacggtttat cgccttgtca aggtaatcaa
    18961 caaagattgt ccggtagaag cattcatttt atctgaaaaa ggcagaggtt tcaaattaaa
    19021 tccaagaagt tccctcgtgg acgttgatgg gaattttaca gaggcttttg atcctgaagt
    19081 aaggcgtgaa aaattactag aacgtctctt gttgactgct cctaagccac attctattta
    19141 tgatttagga gaggaattct acgtaagcga gtcagtagta ctaaaagatc gtcagatatt
    19201 acaagagagt ctagcaattt atgggttaga tttaaaaatg agacaacgaa agctttttat
    19261 tgatggggat gaggctcaaa ttcgttcagc cattctaaat ctactgccaa tgtttaatca
    19321 gttggattta gagcaaatta cacagaataa ggttcagcct cttgacggag aacttgctca
    19381 cttttgtttg ggattactga ttacacttga gagagaattg ggggtaaaca ttccctatcc
    19441 atataatata aatattttct ctcacctgta tatttttatc agtaggaatc gtcgtagtac
    19501 tagtattcat gttgtagcac cttcaaaacc tactattgtt gatgagaaaa tttacagtgt
    19561 ctgtcaaaaa attattcaag aaattgaaca atattttaag atgaaggttg atgcagttga
    19621 gattgactat ctttatcaat acgttgtatc ttcgagattg caaaaaccat tttcttccgg
    19681 gaagcttcct ttttctcagc gagttttaga tgtcactcat tactatttta gccgtatgtg
    19741 tatggacaat agagagattg aaacgacaga tcctgacttt gttgacttgg cgagtcatat
    19801 cagtccctta ctgaggagat tagataatag agtacagatt aagaatagtc ttttatcaca
    19861 aattctttta acctatccta atctagttaa agagttaaca actatttcta aagaagtgag
    19921 tctagtattt ggttttgcgt ccttgagtct ggacgagatt ggttttctag tcttatattt
    19981 tgcacggttt caagaaaagc gagcacgtcc tctaaaaaca gtagtgatgt gtacatcagg
    20041 tgtcggaact tcagagcttt tacgagcacg attagaaaag caatttactg aattggatat
    20101 tattgatgta gttgcttatc atcaattaga tgagctgata aatctatatc cagatttaga
    20161 tttcattgtg acgacggtag ctttgcagga accagcaagt gtcccgtttg tcctagttag
    20221 tgtttttcta accgagggtg ataaacaacg tcttcaagca aaaattcagg agataaacta
    20281 tgaataatct ttcgcttgtc cttatggata tatctgttca aaatcgtcaa gaagcctaca
    20341 aagaattagc aaatcaaatc agccttcttg tttctgaaga tacagaaaaa atagaagagc
    20401 ttctatatta ccgtgagaga cagggaagta tagaggttgc taaaggtgtt cttctaccac
    20461 attgtgaagg aaactttcaa catcatgtct tagtgattac tagattaaaa tcacctatca
    20521 gagaatggtc gaaggatatc cagtgtgttg accttattat cggtttggcc attgcagtat
    20581 cacaggacaa gtcatgtatt aaaacattga tgagaagact agcagatgaa tcattcataa
    20641 atcaattaaa acagttaaca aaagaagaat tacgggagat aatatatgga aatcaaagat
    20701 attcttaatg tgagtctgat ccagacggat ttacagatgc agagcaaaga agaggttttt
    20761 gaggcattag ctcaactatt ggttgagacg ggttatgtgt ctgatagaga ccaatttatc
    20821 gaaggtctgt atcagagaga ggcagaagga cagaccggta ttgggaatta tattgctatt
    20881 ccccatagca agagttctgc tgtggagaag gcgggggtag tcatagctat aaatcacaat
    20941 gagattcctt gggagaccat tgatgggaaa ggggtcaaag taattgtact ctttgcagtt
    21001 ggtgatgata cagaagctgc tagggagcat ttgaagacct tatcactctt tgctcgaaaa
    21061 cttggtaatg acgaagttgt tgccaaatta gttcgggctc agacatctga tgatgtgatt
    21121 gcagcttttt gttaataaga aaaaattttg gagggtatcc gtatgaaaat tgttggtgtt
    21181 gcagcttgta ctgtgggaat tgcccacact tatattgcac aggaaaaatt agagaatgcc
    21241 gcaaaggtag ctggacatgt gattcatgtt gagactcagg ggacaatagg ggtagaaaat
    21301 gaattgagtc aagagcagat tgatgcagcg gatgtagtta ttttagcagt tgatgttaag
    21361 atttctggta tggaacgctt tgagggtaaa aagattatca aggttccaac agaagtggca
    21421 gtcaaatctc ccaataaact gattgctaaa gctgttgaga ttgttacgaa ataactgaaa
    21481 atatttaagg agaaaatata tgttgaaaca cttaaactta aaaggtcact tattgacagc
    21541 catttcctat gtgattccaa ttgtttgtgg tgcaggattc ttagttgcca ttggtttagc
    21601 aatggggggt ggtgttcctg acgctcttgt agcaggaaaa ttcactatct gggatgcttt
    21661 agcaactatg ggtggtaaag cccttggtct cttgccagtt gttattgcta caggtttgtc
    21721 ttactcgatt gctggtaagc cagggattgc accaggtttt gttgttggtc taattgccaa
    21781 ttctgttggt tcagggttta tcggtggtat cttgggaggt tatatagctg gtttcttggt
    21841 tcaagcgatt attaaaaagg tcaaagtacc aaactggatt aaaggtttaa tgccaacctt
    21901 gattattcct tttgtagcct ctttggtaag tagtttgatt atgatttata ttattggagc
    21961 gcctatcgca gcctttacca actggttgac gagcttatta caaagcttgg gaagtgcttc
    22021 aaatggtttg atgggggcag ttattggagt tctcagtgct gttgactttg gtggcccact
    22081 taataaaaca gtctatgcgt ttgtgttgac tttacaggct gaaggtgtga aagaaccatt
    22141 gactgctttg caattggtga atactgctac accagttgga tttggattgg cctattttat
    22201 cgcgaaatta ctcaaaaaaa atatctatac tcaagaggaa atcgaaacat tgaaatcggc
    22261 tgttcctatg ggaattgtca atattgttga aggtgtaatt ccgattgtta tgaataactt
    22321 ggttccaggt ctcattgcaa caggtatcgg tggtgctgtt ggtggtgctg tttctttgac
    22381 aatgggtgct gattctgccg tgccatttgg tggagtgctt atgttaccaa ccatgactcg
    22441 tccagtagct ggtatttgtg ctttgttagc caacattgta gtcacaggac ttgtctacgc
    22501 gattttgaaa aaaccaataa aacatacaga accagttatg actgttgaag aagagattga
    22561 tttgtcagat attgaaattt tgtaagaggg taacgatgtc aagaattgaa ttttcaccat
    22621 ctttgatgac catggatttg gacaaattca aagagcagat tacttttttg aatgataaag
    22681 tagcatctta tcatatcgat attatggatg gccattttgt tcccaatatt accttgtctc
    22741 cttggttcat tcaagaagtt caaaaaatta gtgacacacc tttatcagtt catctgatgg
    22801 tcacagaccc aaccttttgg gtagatcaag ttctcgattt acaatgtgag tatatttgta
    22861 ttcatgctga agttctgaat ggtcttgctt ttcgtttgat tgataaaatt catgatgcag
    22921 gtctaaaggc tggtgttgtc cttaatcctg aaacacctgt ttctacaatc tttccctaca
    22981 ttgatttact tgacaaagta actattatga ctgtagatcc aggttttgca ggacaacgtt
    23041 ttttgaagtc taccttgtat aaaatccaag aactccgtca gcttagagtt cagaatggtt
    23101 atcactacat cattgagatg gatggttctt cgagtcgtaa gactttcaaa caaattgatg
    23161 tggcaggacc agatatttat gttataggtc gcagtggatt atttggtttg gatgacgata
    23221 ttgccaaagc ctgggatatc tgttctagag attacgaaga aatgaccgga aaaacaatgc
    23281 caatcaaata atggtttgag aagaaattta ttagttagga ggaatatatg tcactacaat
    23341 cagttaacgc cattcgtttt cttggcgtag atgctattaa caaatctaat tctggtcacc
    23401 cgggaatcgt catgggtgct gcgccaatgg cttatagctt atttacaaaa caccttagaa
    23461 ttacacctga gcagccaaac tggattaacc gagatcgctt tatcttgtct gcgggtcatg
    23521 gatcaatgct actgtatgct ctcttgcatt taacagggta taaggatgta tccatggacg
    23581 agattaaaaa tttccggcaa tggggatcta agacacctgg tcatcctgaa gtgacgcata
    23641 cgtctggtgt ggatgcgaca tctggtccgc ttggtcaggg gatttctact gccgttggtt
    23701 tcgcccaagc agagcgtttt ttagctgcta agtacaacaa agatggtttt cctatttttg
    23761 accattatac ttatgttatc gctggagacg gtgacttcat ggaaggagtg tctgcggagg
    23821 cggcttctta tgcaggtcat caagctttag ataagcttat cgtcctctac gactccaacg
    23881 atatctgctt ggatggtgag accaaagata ctttctctga aaatgttcgc gcccgttacg
    23941 atgcttatgg ttggcataca gttctggtag aagatggaac agatttagca gcaatttcta
    24001 cagcaattga gacggccaag ttttctggta agccgagttt gattgaagtg aaaacggtaa
    24061 ttggttacgg ctcacccaat aaaagtggta caaatgctgt tcatggtgca ccactaggag
    24121 cagaagaaac aggagcaact cgtaagtttt tgggatggga ttacgatcca tttgaagtac
    24181 cagaggaagt atattctgat ttcaagacaa atgtagcgga tcgtggtcag gaggcatacg
    24241 atgcttgggc tagtttggtg tctgattaca aggttgctta tcccgaagtt gctagtgaga
    24301 ttgacgctat tgtagctgga aaatcccctg taaccattac tgaaaaagac ttccctgtct
    24361 atgagaatgg cttctctcaa gcaactcgta attcgtccca agatgctatt aatacagcag
    24421 cagcagtttt accaaccttc ttaggtggat cggcagactt agctcactcc aacatgacct
    24481 acatcaaggc agatggctta caagataaat ataatccatt aaaccgcaat attcagtttg
    24541 gggtacgtga atttgccatg ggaacaatcc tcaatggaat ggctcttcat ggtggtttac
    24601 gagtttatgg cggaaccttc tttgttttct ctgactacgt caaagctgct attcggctat
    24661 cagccattca ggagttgcct gtaacttatg tctttaccca tgattcaatt gccgttggtg
    24721 aagatggtcc aactcatgaa ccagttgaac atttggcagg tttacgctca atgccaaact
    24781 tgactgttat ccgtccagcg gatgcccgtg aaactcaagc ggcttggcat catgccttga
    24841 ccagtaccac cactccaact gtcattgtct taacccgtca aaacttggta gttgaagaag
    24901 ggacagactt tggtaaggtc gctaaaggag cctacgtcgt gtatgatacc ccgggatttg
    24961 atactattat cattgctaca ggatctgagg tcaatctagc tatcaaagct gctaaggaat
    25021 tggttttaca aggtggtaaa gtacgtgtgg tatctatgcc ctcaaccgaa ctatttgatg
    25081 ctcaagatgc tacctacaag gaagacattt taccatctaa gactcgtcgt cgtgtggcca
    25141 ttgaaatggc agcgacccaa agttggtaca agtatgttgg tttggatggc gcggtcatcg
    25201 gtattgacat cttcggtgcg tctgccccag ctcagactgt gattgataat tatggattta
    25261 cggtagagaa tatcgttgct caagttaagt ccctatagaa accaattaca atgaagatac
    25321 agctgttgtc agactagcag atgtagtgat agacactaat cagatgattg gttatttaaa
    25381 aactataatg agaatgtaat aatttatcta cgaaagttat agtagatagt atacacaata
    25441 gagtataccc tgaaacggtt gcgaagtacg ctaatcactt tgctactgat ctagatagtt
    25501 tctttaatca ataaacacag catccacaga ttgacttagg atattgtaag ttttttgaaa
    25561 gctagagaga aggtctctaa aattaaaaaa cgcatagtat aggatgttga aatgatgaac
    25621 tgccccccaa aagttagaca gaaaaaatct aacttttggg gtgttttatt atgaaattaa
    25681 gttatgaaga taaagttcag atctatgaac taagaaagca aggacaaagc ttcaaacagc
    25741 tttcaaaaag atttggtgtg gatgtttctg gtctaaagta catggtgaaa ttaattgacc
    25801 gttatggcat agagttcgtc aaaaaaggaa aaaatcgtta ctattctcct gatttaaaac
    25861 aagaaatgat taataaagtc ttacatgaag gctggactaa agatagagtt tctcttgaat
    25921 acggtctccc aagtcgtacg atacttctta actggctagc acaatacagg aaaaacgggt
    25981 atactattgt tgagaaaaca agagggagag tacctgagag cggagaatgc catcctaaaa
    26041 aagttaagag aactccgatt gaaggaggaa aaagagaaag aagaaagaca gaaattgttc
    26101 aagaattaat gactgagttt tcgttagctc ttcttctaaa agccattaaa ctagctcgtt
    26161 cgatctacta ctatcacttg aaacagctag ataaaccaga taaggaccaa gagcttaaag
    26221 ctgaaattca atccatcttt atcgaacaca agggaaatta tgcttatcgt cggatttatt
    26281 tagaactaag aaatcgtggt tatctggtaa atcataaaag agttcaaggc ttgatgaaag
    26341 tactcaattt acaagctaaa atgcgacaga aacgaaaata aaggagacgt tggtaagaag
    26401 gcagagaatc tcattcaagg ccaatttgaa ggatctaaaa caatggaaca gtgctacaca
    26461 gatatgacag aatttgccat tccagcaagt actcaaaagc tttacttatc accagtttta
    26521 gatggcttta atagcgaaat tatcgcctat aatctttcaa cttcacccaa cttagaacaa
    26581 gtacaaacaa tgttggaaca ggcattcaca gagaagcact acgagaatac gattctccat
    26641 agtgaccaag gctggcaata ccaacacgat tcttatcatc ggttcttaga gagtaaggga
    26701 gttcaagcat ctatgtcacg caagggtaat agcccagaca atggtatgat ggagtccttc
    26761 tttgggattc tgaaatcgga aatgttttac ggttatgaga agtcgtttca gtcgcttaag
    26821 caattggaac aagctattgt agactatatt gattactaca acaataaacg aattaaggta
    26881 aaactaaaag gacttagtcc tgtgcaatac agaactaaat ccttcggata aattaattgt
    26941 ctaacttttt ggggggcagt acatttttgg tatatataaa atttgtagga gctatatcta
    27001 caattttata ttcccagttt atggatgtcg cttactatat tcacaatgtt atccagtgtt
    27061 ttttctctaa tatttaagga gtgttctgtt tctcgaataa attcttcaaa gtttaacccg
    27121 tcaacttgtt cctgaacaag aaaataatca tccacgatat aaaattcatc agttaaatta
    27181 gtagtataac ttttatcggc taattttttt agcatgtaag cctcattttt tatatcatca
    27241 agtgctgtcc attctccttc ggcatcataa ttcacaaaag gtcttgactg cttgatgatt
    27301 actttttgct cgtccgattt tctaattgcc cgataaacat ttcctttatt tgatatctta
    27361 ataatttttt ctattttgta tttatttatt gcagagtcct tacttgaaac ttcacatgtg
    27421 gtttgaaaat aaatcctttt ttcttcttct gaaaataaat ccattttcca gctaggaaga
    27481 ctagggaaat tttgtctctt atcttctaca tagttcttcc ttttttcatc tagcaataaa
    27541 tagatgactt ttttattttt tcatcataag cttgtttttt taaaaaagcc ccatatctat
    27601 aatgaactgg agaatgcatt ccacattgat agtcagatag tatttttgga gccttaaatt
    27661 ctgacagttt attcgtaaga ttacaaatca tactcttggc ttcagattct gacttaggat
    27721 atagagttat aaatttgtta gcagtagggc tcatttccct aggggaatta atttttttta
    27781 attcctctaa atttttaacg actttaaagc tacaattatt tagttgggat agtttataca
    27841 caatcttaaa aatatttaca gcgtctttta tttgggagct tatgtgtatt ttccagcctt
    27901 gtgcaggcac cttatctgat aaataatagt aattccaaat atcaccctgt tggaaatttt
    27961 tatcacattt taaacattct ttctctaata aatccataac aaactcctaa ttattaaaat
    28021 aggctagaga cacagcacta gcctattccg taagtaaagc tacttatttt atataaaata
    28081 taactagcga cctgtaatta aacaagtaaa agaacaatac ttagggagac ctgtgacaat
    28141 gacatcttcc tctggaagta gttctaattc aaacaatgtt tgttccatga ctgtatcctc
    28201 ctgttatgat aaattccaga aagcatagag caaattcgtg gttcgtctga ctaaatttct
    28261 tatctgaaca ccaccttcaa atacaaattt tagtcaaact tttatttttt ctaactttct
    28321 aattatattc taccatgtgt ttttatatgt caagaatttt ctgaataaac tgtttatttt
    28381 ttattttttg caaattgttt aaaatctttc aattggattc acttattact ttaggacatt
    28441 gaaacttctt tcgccagagg tgcttatatt actgggaagt tgaagattga aatgtggtat
    28501 aataagaggt aatagagttt tggaaagaga gagaagatga tttcaaagag attagagttg
    28561 gtagcttcct ttgtgccgca gggagccatt ttactagatg tggggagtga ccatgcttat
    28621 ttgcctatag agttagtcga aagaggaaaa atcgaaagtg ccattgcagg tgaagttgtg
    28681 gagggacctt atcagtctgc tgtcaaaaat gttgaggccc acggcttgga agaaaaaatc
    28741 caagtccgtt tagccaatgg tttggcagct tttgaagagg aagaccgagt gtctgtcatt
    28801 accattgctg gcatgggtgg tcgtttgatt gctaggattt tagaagaagg tttggggaag
    28861 ttagctaatg tagagcgttt gatcctccag cccaataatc gtgaagacga cttgcgtatc
    28921 tggctacagg atcatggatt ccagattgta gcagaaagca tcttagaaga agctggaaag
    28981 ttttatgaga ttttggtggt ggaagcagga caaatgaagc tatcagccag tgatgttcgc
    29041 tttggtccct tcttgtccaa agaagtcagt ccagtatttg tccaaaaatg gcaaaaagaa
    29101 gctgagaagc tagagttcgc cctcggacaa atcccagaaa aaaatctgga agaacgtcaa
    29161 gttctagtag ataagattca agctatcaag gaggtgctcc atgttagcaa gtgaagtgat
    29221 ccaagcttat gaagcctttt gccctcagga attttctatg gagggagaca gccgtggtct
    29281 gcaaattggc actttagaca agggtatcca aagggtcatg gttgccctcg atattcgtga
    29341 agagacagtg gcagaggcca ttgaaaaggg tgtggacttg attatcgtca agcacgcgcc
    29401 tatctttcgt cctatcaagg acttgcttgc cagccgtccg caaaatcaga tttacatcga
    29461 cctgattaag catgacatcg cagtttatgt cagccatacc aatattgata tcgttgaaaa
    29521 tgggctcaat gactggtttt gtcagatgct agaaatcgag gagacgactt atctgcagga
    29581 aacaggtcca gaacgtggaa ttggacgtat tgggaatatt cagcctcaga cattttggga
    29641 attggcccaa caggtcaagc aagtctttga cctagatagc cttcgaatgg tgcattatca
    29701 agagaatgat ttgcagaagc ctatttcaag agtagcaatt tgtggtggaa gcgggcagtc
    29761 tttctataag gatgctttgg caaagggggc agatgtctat atcactggtg atatctacta
    29821 ccatactgct caggatatgc tgtctgatgg cttgttagca ttggatccag gtcactatat
    29881 cgaagtgctt tttgtggaaa aaatcgcagc actccttact caatggaaag agaaaaaagg
    29941 ctgggaacta gagattttac ctagtcaagc atcgaccaat cctttccgtc atatctagtt
    30001 agaaagtgaa gacaatgaaa aaagttgcca ttattggagc aggaattgtg ggagcaacag
    30061 ctgcctacta cctctcgaga gaaagtgacc tagaggtgac cgtttttgac catgagcaag
    30121 gtcaagccac caaggccgca gcaggaatta tcagtccttg gttttccaaa cgccgtaata
    30181 aagcctggta caagatggcg cgcttggggg ctgattttta tgtggattta ttagctgatt
    30241 tagagaaatc aggacaaaaa atcgactttt accagcgttc gggagtcttt ctcttgaaaa
    30301 aggatgaatc caagttggaa gaactttatc aactggccct ccagcgcaga gaagaatctc
    30361 ccttgatagg gcaattagcc attctggacc aagcctcagc taatgaatta ttccctggtt
    30421 tgcagggatt tgaccgcctg ctctatgctt ctggtggagc gagagtagat ggccaactct
    30481 tggtaactcg tctgctagaa gccagtcatg tcaagctggt caaagaaaaa gtgactctga
    30541 caccgttagc atcaggctac cagattggtg aagaggagtt tgagcaggtt attttggcga
    30601 cgggagcttg gttgggggac atgttagagc ctttaggtta tgctgtggat gtccgtcctc
    30661 aaaaaggaca actacgagat tatcagctgg tccaagatat ggaagcttac cctgttgtca
    30721 tgccagaagg ggagtgggat ttgattcctt ttgcaggtgg gaaattgtcc ttaggcgcta
    30781 cccatgaaaa tgacatggga tttgatttga cggtagatga aaccttgctc caacaaatgg
    30841 aggaggccac cttgactcac tatctgattt tggctgaagc tacttcaaaa tctgagcgtg
    30901 ttggaatccg tgcctacacc agtgatttct ctcctttctt tgggcaggtg cctgacttaa
    30961 ctggtgtcta tgcagccagt ggactaggtt catcaggcct cacaactggt cctattattg
    31021 gttaccattt agctcaactg atccaagaca aggagttgac cttggaccct gaaaactacc
    31081 caattgaaaa ctatgtcaaa cgagtaaaaa gcgaataata ctcaatgaaa atcaaagaac
    31141 aaactaggaa actagccgcg gattactcaa agcactg
//
LOCUS       DAVAGB010000024        29955 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVAGB010000024 DAVAGB010000000
VERSION     DAVAGB010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29955
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.024"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(142..543)
                     /locus_tag="VQO19_001196"
     CDS             complement(142..543)
                     /locus_tag="VQO19_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET1349471.1"
                     /translation="MLFFSISNDLLQLLTSWKEQQRYELAKFGILSNPEQFVFTYIDT
                     KGNINKPLHADYLNNKMKSIRKRHKELTHATPHKLRHTGATLAKKAGMSLEAISKALT
                     HSDTGTTQIYVNTSNVVPMTVGEFALKSLKQ"
     gene            complement(919..2127)
                     /locus_tag="VQO19_001197"
     CDS             complement(919..2127)
                     /locus_tag="VQO19_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET1349472.1"
                     /translation="MNYIKRPHYLDFLRRHRDRQIIKVVSGVRRAGKSVLFQLYKEEL
                     IATGVDEDQIISINFEDLSYYDLRHFQTLFAYIKEQLIGEKTYYIFLDEIQHVEKFEL
                     VADSLFILPNVDLYLTGSNAYFMSSQLATNLTGRYVEIEVLPLSFEEYLSGQSLTENL
                     NTTEIFNNYLFSAFPYLLQTSSYAEKIDYLRGIYNSILLNDIVTRLGNPNPTIIERIV
                     RTLLSSTGSLISTNKIRNTLVSQNVSISHNTLENYLTTLTDSLLFYSVPRFDVKGRAL
                     LQRLEKYYPVDLGLRHLLLPDHKEDIGHILENMVYLELRRRYSQVYVGNLDKYEVDFV
                     VVTDLGHYAYYQVSETTLAPETLERELRPLDAIKDQFPKYLLTMDTIQPTANYNGIEK
                     KNIIDWLLEK"
     gene            2532..2708
                     /locus_tag="VQO19_001198"
     CDS             2532..2708
                     /locus_tag="VQO19_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349473.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            3109..5322
                     /locus_tag="VQO19_001199"
     CDS             3109..5322
                     /locus_tag="VQO19_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HET1349474.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     ISLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(5544..6020)
                     /locus_tag="VQO19_001200"
     CDS             complement(5544..6020)
                     /locus_tag="VQO19_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HET1349475.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLQDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            6243..9443
                     /locus_tag="VQO19_001201"
     CDS             6243..9443
                     /locus_tag="VQO19_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HET1349476.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTIGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSAAASTRVIEAKDGA
                     ITISSHEKLRAALHRMVPIEAKKKYKLRFKIKTDNKIGIAKVRIIEESGKDKRLWNSA
                     TTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQLSEDSQTD
                     KQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKEV
                     KKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSIS
                     SQADRTYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEW
                     LHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPE
                     HFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFY
                     QDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKSPIDKDKMQTMYHWIDKSFAPL
                     LVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQS
                     DSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRPSYLSAFNKMDKTAMYNAEKGFGFG
                     LSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTET
                     DAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLG
                     SNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSK
                     KNIGYFFFKKSSISMSKALQKGAWKGINEGQSDKEVENEFLTISQAHKQNGDSYGYML
                     IPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLK
                     RGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKNH
                     SDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            9796..10181
                     /gene="tnpA"
                     /locus_tag="VQO19_001202"
                     /pseudo
     CDS             9796..10181
                     /gene="tnpA"
                     /locus_tag="VQO19_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(10560..11189)
                     /locus_tag="VQO19_001203"
     CDS             complement(10560..11189)
                     /locus_tag="VQO19_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HET1349477.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(11199..12200)
                     /locus_tag="VQO19_001204"
     CDS             complement(11199..12200)
                     /locus_tag="VQO19_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HET1349478.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISALEAKYEFSKFARFTDYCFGIDPLMIDNQNLEMFPRDSASLEEV
                     ENRMRLLKETYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(12231..12872)
                     /locus_tag="VQO19_001205"
     CDS             complement(12231..12872)
                     /locus_tag="VQO19_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HET1349479.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKGYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(12891..13706)
                     /locus_tag="VQO19_001206"
     CDS             complement(12891..13706)
                     /locus_tag="VQO19_001206"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HET1349480.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIQAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            13977..14411
                     /locus_tag="VQO19_001207"
     CDS             13977..14411
                     /locus_tag="VQO19_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET1349481.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            14423..15613
                     /locus_tag="VQO19_001208"
     CDS             14423..15613
                     /locus_tag="VQO19_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HET1349482.1"
                     /translation="MIKKVTIEEIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELAHHDLGFLYTPSCMAEYKINGDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            15624..16115
                     /locus_tag="VQO19_001209"
     CDS             15624..16115
                     /locus_tag="VQO19_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET1349483.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            16130..16909
                     /locus_tag="VQO19_001210"
     CDS             16130..16909
                     /locus_tag="VQO19_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET1349484.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            16896..17714
                     /locus_tag="VQO19_001211"
     CDS             16896..17714
                     /locus_tag="VQO19_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET1349485.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLIMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            17714..18007
                     /locus_tag="VQO19_001212"
     CDS             17714..18007
                     /locus_tag="VQO19_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET1349486.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            18029..19930
                     /locus_tag="VQO19_001213"
     CDS             18029..19930
                     /locus_tag="VQO19_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HET1349487.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYLVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGMHY
                     IEGAYWSAEPDLPYLHRRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            19990..20991
                     /locus_tag="VQO19_001214"
     CDS             19990..20991
                     /locus_tag="VQO19_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET1349488.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(21101..21436)
                     /locus_tag="VQO19_001215"
     CDS             complement(21101..21436)
                     /locus_tag="VQO19_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349489.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(21447..21689)
                     /locus_tag="VQO19_001216"
     CDS             complement(21447..21689)
                     /locus_tag="VQO19_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349490.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTIIFFIIPPIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(21699..22241)
                     /locus_tag="VQO19_001217"
     CDS             complement(21699..22241)
                     /locus_tag="VQO19_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HET1349491.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKAGITAIDPDMLSEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLGILIGEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKDPDED"
     gene            complement(22257..22451)
                     /locus_tag="VQO19_001218"
     CDS             complement(22257..22451)
                     /locus_tag="VQO19_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET1349492.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            22617..23567
                     /gene="rsmH"
                     /locus_tag="VQO19_001219"
     CDS             22617..23567
                     /gene="rsmH"
                     /locus_tag="VQO19_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HET1349493.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQQRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQEASLTAYEVVNHYDYHDLIRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKSAKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMEMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            23579..23896
                     /gene="ftsL"
                     /locus_tag="VQO19_001220"
     CDS             23579..23896
                     /gene="ftsL"
                     /locus_tag="VQO19_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HET1349494.1"
                     /translation="MAERMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            23900..26152
                     /locus_tag="VQO19_001221"
     CDS             23900..26152
                     /locus_tag="VQO19_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HET1349495.1"
                     /translation="MKWTKKVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGSKGNGITY
                     ANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTISSTLQSFMETQ
                     MNAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGLTKDFVWRDILYQSNYE
                     PGSTMKVMTLAAAIDNNTFPGGEVFNSSELKVADATIRDWDVNEGLTGGGMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGIPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFITALYDPNNQSVRKSQKEIVGNPVSKDAA
                     SQTRTHMVLVGTDPRYGTMYNHSTGKATVNVPGQNVALKSGTAEIADEKNGGYLVGST
                     NNIFSVVAMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERAVAMKDSLNLQSTA
                     KTLDQVTNQSAYAMPSIKDISPGDLAEALRRNIVQPIVVGTGTKIKESSVEEGSNLAP
                     NQQVLLLSDKAEEVPDMYGWTKATAEAFSKWLNIELVFEGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            26154..27134
                     /locus_tag="VQO19_001222"
     CDS             26154..27134
                     /locus_tag="VQO19_001222"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HET1349496.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIKFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLIASVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVVFYLFYERGGDMLSVFGYQVHLGIFYILFALFWLVGF
                     SNAVNLTDGIDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFVFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            27743..29848
                     /locus_tag="VQO19_001223"
     CDS             27743..29848
                     /locus_tag="VQO19_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET1349497.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
BASE COUNT         9335 a         5202 c         6487 g         8931 t
ORIGIN      
        1 gtttcaaagc actcaaaagt tcaccttatt tttatagtaa aatgaaataa gaataggaca
       61 aatcgatcag gacagtcaaa tcgaattcta acaatgtttt agaagtagag gtgtactatt
      121 ctagtttcaa tctactatac cttattgttt tagagacttt aaagcaaatt cacctactgt
      181 cataggaact acattagaag tatttacata aatctgtgtt gttcctgtgt cactgtgtgt
      241 tagagcctta gaaatggctt ctaagctcat tcctgctttt ttagcaagtg tcgctcctgt
      301 atggcgtaat ttgtgaggtg tagcgtgtgt cagttcttta tgtcgctttc taatgctttt
      361 cattttattg ttcagatagt cggcatgtaa aggcttgttg atgtttcctt ttgtgtcgat
      421 atatgtaaaa acaaattgtt ctggattact gaggatgcca aactttgcta gttcatatct
      481 ttgttgttct ttccaagagg taagaagttg aagtaaatca ttagaaatag agaaaaatag
      541 gatagcaaaa gctctatttc aggagaaaat gaagcaaata tttccataat aaaacgcata
      601 ttatcaaggt tgttcaatac ctgatactat gcgcttttct gattttaaag actgattgct
      661 cagtctcttt ttcattataa ttcagttaca atttaatctt atttgagaaa gtgggtgatg
      721 ctattctcta ataagactat gatattaatt tttgatagta cttccagaaa ttatagatcc
      781 cctttcatcc ccaatttcta ttttcaagtg tccgtattat atagcgtatt cgaaattcac
      841 tatatcttgt taggatttgg gtagaatcat tgataacaga ctgttgcaaa tctaattagc
      901 tgtatgattt atatttatct atttttctag taaccaatct ataatgtttt tcttctcgat
      961 tccattgtaa ttggctgttg gctgaatcgt atccattgtt aatagatact ttgggaattg
     1021 atctttaatg gcgtctagtg gtctaagttc tctttctagt gtttctggag caagtgttgt
     1081 ttcactgact tgataataag cgtagtgacc aagatcagtt acaacaacaa aatcaacctc
     1141 atatttatct aaattaccaa catatacttg tgaatatcta cgtctcaatt ccaaatagac
     1201 catattttcc aagatatggc caatatcttc tttgtggtct ggcaataaga ggtgtcgtaa
     1261 acctaaatca acgggataat atttttctaa gcgttgcaat aatgctctac cttttacatc
     1321 aaaacgtgga acggaataaa aaagcaaact atctgtcaaa gtcgtcaaat aattttccaa
     1381 agtattatgg gagattgaaa cgttttggct gaccagggta ttgcgaatct tatttgttga
     1441 tattaagcta cctgtactac tgagaagggt tcggacaatg cgctcaataa tagtaggatt
     1501 tggatttccc aatctagtga caatatcatt taacagtatg gagttatata ttcctcttag
     1561 ataatcaatt ttttcagcgt aagatgatgt ttgcaataag taagggaaag cactaaagag
     1621 ataattgtta aaaatttctg ttgtattcag attttctgtg agagattgac ctgatagata
     1681 ttcttcaaat gacaatggaa gaacttctat ctcaacatac cgaccggtca agtttgtagc
     1741 taattggcta ctcataaagt aggcgtttga tccagtcaaa tagaggtcaa catttggtag
     1801 tataaataga ctatctgcta ccagttcaaa tttttcaaca tgttgaattt catctaaaaa
     1861 gatatagtat gttttctctc caattaactg ctcttttata taagcaaata atgtttgaaa
     1921 atgtcggaga tcatagtaac tcagatcctc aaaattgatg gatatgattt gatcctcgtc
     1981 taccccagtt gctattaact cctctttata gagttgaaag agaacagatt taccagctcg
     2041 cctaactcca ctcacaactt tgatgatttg tcggtcacga tgtcttctta aaaaatctaa
     2101 ataatgtggt cttttgatat agttcataat agttacctca aagatagtat aatacaaata
     2161 gatgttattt tcaaatattt agaaataatg tttaatttat ttaattattt ctaattgttt
     2221 agaaataata tctggaacta tttaaatatc ttcaagatag aaaaagaaat tgtacttgtt
     2281 gatgttgaat catttgtgtt aacaagtcat ttagaagcat ttaagaaatt agtgaaatga
     2341 aaaactcatg gcagaacaaa ttgttgggta tatggtctat tactaacaac tactgctagt
     2401 ttatgagata gatatttaat tattctcgga taaataggat aagcgtgctg aaaacttaga
     2461 tatgacaaac aaaataaaat ttttaaaagc tacatagaaa catggtataa tgtatctaaa
     2521 ggaggtagca tatgtcctta gatatagata aagaaaagat gacaatcatg ggaatagctt
     2581 ttgaaaacag atccgttttt aagagtgttt ggtatgcttt aagtacaaat atgattgaag
     2641 gatggcgacc tacggttagt gatgttgaaa aattacgaga tgaagctctt gctctgggga
     2701 tgacttaatg aagcgcaact gttatgaatc ttatgactat gttgatccgg ataatttata
     2761 taccgatccg ggttcttcag ttctaagaaa taagcaggaa ggaaaaaagc acgtgagctt
     2821 gaatatcgta tgattgctag taagagtttg aaattattta tcaatcctat cttagttaat
     2881 agtttaaaag tagtttgttt cacaactgca taagcttaga aaagttgaaa agtgataact
     2941 ctttaataaa ctcttggttt gttaaaagat attttgtcca ctgcattttt tcaattgact
     3001 attatttgtc atagatataa cagatagaac attgcattca gaataatgaa aaacgcatca
     3061 aaaatggtgc gttctgtttt tatgctacca taaaaggagg aaaacaaatt gaaaattttt
     3121 aagggagagt tttatcgaat ctctgtatta acagacaagc tagtaaggtt agaatactct
     3181 cgaactggaa attttgagga tagaacgaca caacttatct ataatagaga ttttggccaa
     3241 atttcgttag attatatcga gacatcaaat gtactagata ttatgacgga ctattttcat
     3301 ctgcacttta ataaaggaga atttaacgcc gaaaatttat ttatagaatt aaaaggaaat
     3361 tttgccgtat atggtagtcg ctggtatttt ggtgaatcta ttgaaacgtt aaaaggaaca
     3421 gctcggactc tggataaggc agatggagca atctcgttag aagatggaat tattagccga
     3481 aatggtatag ccttattgga tgattctcaa ggatttattt gggatgaaca gtctggttat
     3541 attgagagag aaaatcaaat tgacctgtat ttctttgcct atgggcatga ttatagagga
     3601 gcaatcagag acttttacca tttgactggt tcaacaccct tgttgccaag atatgcttta
     3661 ggcaattggt ggagtagata ttggccttat acgtcggatg aatacttgga tttaatagac
     3721 agatttgaaa cagagaaaat tccattatct atcggtgtgt tagatatgga ttggcatata
     3781 actgacattc cagctcgttt tggaagtggc tggacaggat atagttggaa tagaaactta
     3841 ataccaaatc cagaacagtt attgcaacaa cttcatgata gaaagttaaa actctcctta
     3901 aatgtccatc ctgctgatgg gatacgggct tatgaagaag cttatcctca aatcgcaaaa
     3961 cgattggggt taaatgtaga actagaagaa cctgctattt ttgatttttt taatccctct
     4021 tttagggaag cctactttaa agatgttcat tatgagctag aaaagcaggg agtagatttt
     4081 tggtggattg actggcaaca agggacacaa ggtatgctag atccactttg gcttttaaac
     4141 cattatcact atcaagatag ttgtaaaaat gcagaaggtg gtttgatttt atcaagatat
     4201 gcaggtcctg gtagtcaccg ctaccctgtt ggtttttcag gggatactat tattagttgg
     4261 aattccttaa gatttcaacc ctattttaca gcgacagcat ctaatatcgg ttatagttgg
     4321 tggagtcatg atatcggtgg acatatgttg ggggattatg acgaagagct acaaactaga
     4381 tggctacagt ttggtgtttt tagtccgatt actcgattac atagttctag aagtcctttt
     4441 aatagtaaag aaccttggtt cttttcagaa acaacatcta agattatgaa gaaatacctt
     4501 cgtttgagac atcagatgat tccctatcta tataccatga atgtaaagac acatgaggaa
     4561 ggtgccccat taatcagtcc aatctattat ttctatccag agaatgatga gagctataat
     4621 gttccaaacc aatacttttt tggaacagaa ctgatggtgg ctcccattgt agaaaagatg
     4681 gatttgacat tccaatctgc aaaagtagat gtatggttcc ctgaaggtga atggtatgac
     4741 ttcttttcag agaaaaaata cacaggtggt gtgaagttaa gtgtttatag ggacatctcg
     4801 actacgcctg tgtttgcaaa aagtggtgca atcattccct tggttggttc tgagataggt
     4861 atgggtgttg atttacctga ggttgtagat tggtatgtat tcccagggaa acaacattct
     4921 tttgaaatgc ttgaagatca aaatggtcaa agatataaaa caagattatc aatcgattgg
     4981 gaaatgggaa tggtagagtt agcattacaa ggagattcta gtatcgttcc aagcaataga
     5041 aaacatagaa ttcattttaa aggaacgaat gtgtctataa ttgaattgcc aaataagaat
     5101 gatacagcta aatttgaatg gaaagataat aaaaggacat ctttaaatga cgaagttttt
     5161 agactactaa agacagcttc tcttccatat gaattaaaag atagattgtt aaatcaattc
     5221 atcaatgcga aaaactctca tgacttaatg aatatcttgc atcatcagga taaggaattg
     5281 agagggcgtt tgttggaaat gatatttact agccaaaact aattgatata attagaaagt
     5341 catttgttta gtgtatatga agattctgta tggtattcgt tatcactggt cacattgaaa
     5401 atgtgaaata agcacctaca acatagactt tacaacactt catgtttcat atcatggggt
     5461 gtttttctat ttaagtcaaa gcccatcaaa aaatctcact attcatcagg ttaaaggaaa
     5521 cctaatcata gtgagattgt gaattatagt agagtttgta tcgcctcttc aatttgtttt
     5581 gggtctgttt ttgaagaaaa gcgttcaaag acttgcccat ctcgaccgat gagaaactta
     5641 gcgaaattcc attcgactcg ttttcctagt gggccggatt tctggtcttg taaccagaca
     5701 tagagagggt ctgcttcctt accgttgacc ttaatcttgg caaaacgtgg gaaggtggtt
     5761 tgaaaatgta ggctacagaa ggcgttgatt tcctctgcgc tgccgggtgc ttgtcccata
     5821 aactgattgc aagggaaatc caatatttcg aagccctgat cttgatagcg ttcatagagt
     5881 tcttgaagtc cctggtactg gggcgttaaa ccacatccag tagcagtgtt gacaatcaag
     5941 agaactttgc cacgatagct atccaaggga gttgcttggt tgttttggtt caaaacggaa
     6001 aaatcataaa gtgaagtcat gagggcctct tttctttttc tacattgtaa cagtttttac
     6061 ttttttcgtc gagtcggatg gaagatattg ttgaagaata agccttcaat atgatagaaa
     6121 ccgtttacaa ataactttaa aaatggtatg atttaattaa accggtttac ttagttgcta
     6181 taaatctcta atttgagatt tagttcctat tgattttaca atatgtttat tggagtgtat
     6241 acatgcaaac aaaaacaaag aagctcattg tgagtttgtc ttcacttgtt ttatcaggat
     6301 ttttattaaa ccattatatg acaattggag cggaagaaac gactacgaat accattcagc
     6361 aaagccagaa ggaagttcag tatcagcaaa gggatacaaa aaatttagtt gaaaatggtg
     6421 attttggtca gacggaggac ggaagcagtc cgtggacagg aagcaaagct caggggtggt
     6481 cagcttgggt agaccagaag aatagtgcag ctgcctcaac tcgagtcatt gaggctaagg
     6541 atggggctat cactatctca agccatgaga aattaagggc agcgcttcac cgtatggttc
     6601 ctattgaagc taagaaaaag tataaactgc gtttcaagat taaaacagat aataaaatcg
     6661 ggattgccaa agttcgtatc attgaggaaa gtggtaagga caagcgattg tggaattctg
     6721 caacgacgtc aggaacaaag gactggcaga ccattgaagc agactatagc ccgactttag
     6781 atgttgataa aatcaagctg gagttattct atgaaacagg aactgggact gtttccttta
     6841 aggatattga gctggtagag gtagcagacc agctttctga ggattctcaa acagataaac
     6901 agcttgagga aaagattgat ttaccaattg gaaaaaaaca tgttttttct cttgcggact
     6961 atacttataa ggtagaaaat cctgacgttg cttcagtcaa aaatggaatt ttagaacctc
     7021 ttaaggaagg gacaaccaat gtcattgtca gtaaagatgg caaggaagtg aaaaagattc
     7081 ctttgaagat tctggcctct gttaaggatg catacacaga ccgtttggat gactggaatg
     7141 gcatcatcgc tgggaatcaa tactatgatt ctaaaaatga acagatggcc aaattaaacc
     7201 aggaattgga aggaaaggta gctgatagcc tatccagtat ttcaagtcag gcggaccgca
     7261 cctatttgtg ggaaaaattt tcaaattata aaacgtctgc aaatctgact gccacttatc
     7321 ggaaattgga ggagatggcc aagcaagtga ccaatccttc ttctcgttat tatcaagatg
     7381 aaactgtcgt tcgaacagtc agggattcca tggaatggct gcataaacat gtctacaata
     7441 gtgaaaagag cattgttggg aactggtggg attatgagat cggtacacct cgtgccatca
     7501 acaatacctt gtctctgatg aaagaatact tctctgatga ggaaattaaa aaatatacag
     7561 atgtaattga aaaatttgta ccagaccccg aacatttccg aaagacgact gataacccat
     7621 ttaaggctct aggtggaaac ttagttgata tgggaagagt aaaagtaata gctggtttac
     7681 tgcgtaaaga tgatcaagaa atttcttcta ccattcgctc gattgagcaa gtgttcaagt
     7741 tggtagacca aggtgaaggt ttttatcaag atggatccta tatcgaccac accaatgttg
     7801 cctatacggg tgcttatggg aatgttttga ttgatggcct gtctcaactg ttgccagtca
     7861 ttcaaaagac caagagtcca atcgataaag ataaaatgca aaccatgtac cactggattg
     7921 ataaatcgtt tgctcctttg ctggtgaatg gagaactgat ggatatgagt cgtggacgct
     7981 cgatcagtcg tgcaaatagc gaggggcacg tggccgcagt agaagtacta agagggattc
     8041 accgaatagc ggatatgtct gaaggagaaa ccaaacaacg tttgcagagt cttgtgaaga
     8101 ccattgttca atcggatagt tattatgatg tctttaagaa tttgaagact tataaggata
     8161 tcagtttgat gcaatccttg ttaagtgatg caggagtcgc aagtgttcca agaccaagtt
     8221 acctatctgc ctttaacaag atggataaaa cagccatgta caatgcagag aaagggtttg
     8281 gatttggctt gtcactcttt tccagtcgta ccttgaatta cgaacacatg aacaaggaaa
     8341 ataaacgtgg ttggtatacg agtgatggga tgttctatct ttacaatggc gatttgagtc
     8401 actatagcga tggctactgg ccaacagtta atccatataa gatgcctggt acaacagaga
     8461 cggatgctaa gagagcggat agcgatacag gtaaagtttt accgtctgct ttcgttggaa
     8521 cgagcaaact agatgatgcc aatgcgacag caaccatgga tttcaccaac tggaatcaaa
     8581 cattgactgc tcataagagc tggtttatgc taaaggataa gattgccttt ttaggaagca
     8641 atatccaaaa cacttcaaca gatactgctg caactacaat cgaccagaga aaactggaat
     8701 caagtaatcc atataaagtc tatgtcaatg ataaagaagc ctcccttaca gaacaagaaa
     8761 aggattatcc tgaaacccaa agtgtctttt tagaatcgtc cgattcgaaa aagaatattg
     8821 gttacttttt ctttaagaag agttcaatca gcatgagtaa ggctttgcaa aagggagcct
     8881 ggaagggtat caatgaagga cagtcagaca aggaagttga aaatgaattt cttacgatta
     8941 gtcaggctca taagcaaaat ggagattctt atggctatat gctcattcct aacgtggatc
     9001 gtgccacctt caatcaaatg ataaaagagt tagaaagtag cctcatcgaa aataacgaaa
     9061 cccttcagtc tgtttatgat gctaaacaag gagtttgggg cattgtgaaa tatgatgatt
     9121 ctgtctctac tatttccaac caattccaag ttttgaaacg tggagtctat accattcgaa
     9181 aagaagggga tgaatataag attgcctact ataatcctga aacccaggaa tcagctccag
     9241 atcaggaagt ctttaaaaag ctagagcaag cagctcagcc acaagtacag aattcaaaag
     9301 aaaaggaaaa atctgaagag gaaaagaacc attcggatca aaagaatctc cctcagacag
     9361 gagaaggtca gtcaatcttg gcaagtctag ggttcttgct acttggggca ttttatctat
     9421 tccgtagagg aaagaacaac taatttgttc atcatctaga tgaattacat gaaactgtgg
     9481 aaaatagaaa aaatccgaag aaggccaaat atcttcggat ttttctttta aaaaaggata
     9541 agttgatact tatccttttt tacttcatta ttatgtgact atagcgtttt gaaactagaa
     9601 tagaacgtta taactgctaa aagatttcta taaattcatt tgattttcct aatcaatttg
     9661 ttcgtatcct atttcactcc actatataag tccgtctcgc tccgtgaggt gcgcgtcgaa
     9721 ggttatacca aaaaaactcc aaacgcgata caataaaggt attcaatcca attgtaaagc
     9781 gaaaggagaa aaaatatggc acaaaagact catagtttat catacacaaa gtggatgtgt
     9841 tctatcatat tgtgttcacc cctaagtata gacgaaaagt catctataat caatatagaa
     9901 gtagtttagg cgaaatattt catcgcttgt gtagttataa aggtgttgaa atgatcgagg
     9961 gtcacttaat gccagaccat gtacacatgt tagtcagtat tccgtcgagg ctaagtgttt
    10021 caagttttat ggggtattta aaaggcaaaa gtgcactcat gatgtttgac aaacacgcca
    10081 atctcaagta caagtttggg aatcggaatt tctgggcgga aggttattat gtaagtccag
    10141 tagggcttaa tgaagccaca attaagaaat atagtcaaga ttaaagaaat tatcgagtgg
    10201 atgatttctt cacgagtatg aaaatttgag aactagtaaa gtatgatata tagtaaaatg
    10261 aaataagaac aggacgaaat cgatcaggac agtcaaatcg atttttaaca atgttttaga
    10321 agtagaggta tactattcca gtttcaatct actatagcac tagataaatt gagtgtaaaa
    10381 gaatatgagg atccctttag ggatagtggt aagtaatacc aaagtctctt aaagaggcaa
    10441 gtgacgagtc aagagcaata aggcttgaac aacgtgaaag ccagcgtctt taggcgctgg
    10501 ctgatgattt gggcttatag ctctgagata aaccacccgt tagacgggta gttatgattt
    10561 tatctgagtg taatatactg ttgggcaatc tcgctgatgc ggtcaaagtt gccttgggaa
    10621 gcgagtttat tgagttcgcc accaattcca acggcatctg caccagcagc gaaccattga
    10681 gggatgttgt ttaggccgac tcctccggtt accattacgg aaacttgtgg gatcggtgcc
    10741 ttgactgcag agatatatgc tggactgaga gtactacctg ggaagagttt gatgatttca
    10801 ctaccggctt caagtgcagt cgtgatctct gtgagggtaa tacagcctgg aatgtacggt
    10861 gtgctgtaga gattgcacat tttcgcagtt tcagcatgga aagatggaga aacaacgtaa
    10921 tttgctccag ctagaatggc atctctagca gttacggcat caagcacagt acctgcaccg
    10981 atacaaacac tctgatcgtc ctgatacaag tctacaagtt ccttgatgat ttgtcctgca
    11041 tactgattgg tataggcgat ttcaatagct ttgataccgc ccttgataca agcaatcgag
    11101 gcttgtagtc cttcttcctt tgtatttcct cgaatgacag cgacaatttt ctgttttttt
    11161 agttcaataa tcgtatctga tttggtcatg taattctcct aacgaatgat atcttgtgca
    11221 tttgccagta aattttcaat actagttgcg gaagtggaga gatggtctcc tggaagagtg
    11281 catttgagag ttgcgctcgc aactgcaaag tcaatggtag tttttaggga ggaatgatgg
    11341 agtagttggt aaagggcacc agatataaag gcatccccgc taccaattcg ttgatagact
    11401 gcagttttta gttggacaga ctcttcaaat cgttcttcca gagcataggc ttgatagaca
    11461 tttttgtctt gctcatcact agatcggagg gtatggaaaa tagccttgaa accataggtt
    11521 tcttttaaaa gtcgcatgcg attttccacc tcttctaggc tagcactgtc tcttggaaac
    11581 atctctagat tttggttatc aatcatgaga ggatcaatac cgaagcaata gtcagtaaaa
    11641 cgtgcaaact tagaaaattc atacttggct tctagggctg aaatcatctt tgttctcaga
    11701 ttgagatcca ttgaaacgac aattcctcgg cgcttggctt cttccaagag taggagaagg
    11761 atcgcacgga cctcttgacc gatagctatg gtgattccac taaaatgaaa atggctaatc
    11821 ccctgaaaga gagaatccat atctagcatg tttggccgaa tctggctgat actcgtatgc
    11881 ttacgatcgt agaaaacttc actttgacga caaccaaagc cgttctccaa atagtagagg
    11941 ccgattcgat cgccaagccg acagattgaa ctggtatcga tttggtgctg tttcaagaat
    12001 gtgagaaaac gatctccaat ctcgttggca gggagtgcgg taaagacttt cgttgagata
    12061 cccagggctt gcaaattaca agcgatgtta atttctgatc cgccaaaata agtcgaactg
    12121 gcaacatgat cgccgatact ggtggcatct aatggtgaga ttcgaattaa tggttcgcca
    12181 aacagtaata ttttcgtcat ccattagttc ctttctggtt tagaatagct ttacttggct
    12241 aatacttctt tcaaataagc agcgacttca tcatcttggc agttttcaaa gaagtattct
    12301 tggaagtatt tgccagagat ggtgtctttg aggaagtctt ggtcgattgt tttaaggatg
    12361 gtcatcaaat cattgtgggt gatttgtttc acctcgttta agatacgagc gttgcgttgt
    12421 tcagggatta cacgttctct tgggtagcca ccgcccattt cttcagcaaa taagcgttca
    12481 aacatcaatt tgagggtcag ttctgccccc cagccaaatc ctttggcata agggatagac
    12541 aaggcgttac caccattgat ttgagaataa aggtaagcgt cagttgggtc cactgctaga
    12601 ccacagacaa caccagggaa gctgtttaaa gcaagcatag cccctacacc cgtaccacag
    12661 ccggtaacaa caaagtcaac tgcctttgta tttaaaagga tggcagccat tagtccgttc
    12721 tgcacataag ttaattgact ttctccttct tctccacgca taccatagtt aaataattgg
    12781 tagccttttt tatctgtcgc ttcttttaga ctatcgtaaa taatgtgatt cttgctagct
    12841 tgactatttt cattgattaa tgcgattttc ataagatctt ctttctattt ttactcaggt
    12901 tgttttccga tgtaggctaa gataccgcca tctacatata ggatgtggcc attgacaaaa
    12961 ttgctggcat cactagcgag aaagacagca gggcccatca aatcttcagg atttccccaa
    13021 cgtgcagcag gtgtttttgc aatgatgaac tggtcaaatg ggtggcgaga accatcttct
    13081 tgcaactcac gaagaggtgc tgtttgagga gtggcaatat aacccggtcc aattccgtta
    13141 cattggatat tggctccacc gtattcagac gcaatgttgc gggtcaacat tttcaagccc
    13201 cctttagcag cagcataagc gctaactgtt tcacgtccca gttcgctcat catcgaacaa
    13261 atattgataa tctttccatg ccctttcttt atcatagaag gaataactgc ctttgaaacg
    13321 ataaatggtg cgtttaagtc aatatcgatg accttacgga aatcagcggc gctcatttcg
    13381 cacattggaa ctcggcggat aataccagcg ttattaacga ggatgtcaat gacaccaacc
    13441 tcttgttcga tttgcttgac catggcttgg ataccgtcct cgtctgtcac gtcacagaca
    13501 tatccatggg cttggatgcc aacttcacga taagcttcaa tccctttatt gaccagatct
    13561 tgattgatat cgttaaagac aatagtagcg ccggcttcag cgtaggattt ggcaatagca
    13621 aatccaattc cataagaagc gccggtgatg agagcaattt ttccttttaa agaaaactgc
    13681 tcaattgaga atgatgtatt tgtcatttga tacttccttt caaatttgtt aagacttctc
    13741 tataaccaaa ttatattcta gtaaaccggt tttgtcaata aataaatatt tttatttata
    13801 aaaagattta ttttccttaa aaatggaata ttttgaaact tctgtctatt aaaatgatta
    13861 aaaagataat gaaagcgcta atattttttt aaaaaaacta ttgacaagat aaaaataaag
    13921 gattacaatg gggaatataa agtaaaccgg taaacctaaa caagaaagga gaaaagatga
    13981 aaattgtact tgtagggcat ggacattttg ctacagggat ttatagttct ttacaattga
    14041 ttgcaggcaa tcaagaaaat gtggaggcga ttgactttgt ggaaggaatg tcagcagatg
    14101 aactcaagca aaaaatctta cttgcaattt caaatgaaga agaagtttta atcctaagtg
    14161 atctcttggg aggatcgcca ttcaaggttt cttctaccat aatgggagaa aatccagcca
    14221 aaacaatgaa tgttctctcg ggtttgaact tagccatgtt aatggaagca gtctttgcta
    14281 gaatggctca tagctttgat gaggttgtta ataaatcagt agtggcggcc cagggcggag
    14341 tcgtaaatgg taaagaattg ttttcaacgg atgcagagga agaggaagaa gatttcgaat
    14401 cgggtattta aagggtaaaa gaatgataaa aaaggttacg attgaagaaa taaaatcgcc
    14461 tgagcgcttc ttagaagtac cacttctgac gaaagaagaa gtcggccagg caatcgataa
    14521 ggttattcgg cagttagaac tcaaccttga ctatttcaag gaagatttcc cgacgccagc
    14581 tacctttgat aatgtctatc caatcatgga taacacggaa tggaccaatg gtttctggac
    14641 aggagaactg tggttggctt atgaatacag tcaacaggat gcatttaaaa acatcgctca
    14701 taaaaatgtt ctttctttcc tggatcgtgt caataagaga gtagaattgg ctcaccatga
    14761 tctcggcttc ttgtacacac cgtcttgtat ggctgaatat aaaataaatg gagatggaga
    14821 ggctagagaa gcagccttga aagctgcaga taagttgatt gaacgctatc aagaaaaagg
    14881 tggttttatt caagcttggg gagacttggg caagaaagag cattaccgtt taattatcga
    14941 ttgcttgctc aatatccaac tcttattctt tgcttatcaa gaaacaggcg atcaaaaata
    15001 ctacgatatt gcagaaagcc atttctatgc ttcagctaat aatgtaatcc gtgatgacgc
    15061 ttcgtccttc cacaccttct attttgatcc tgagacaggt caacccttta aaggtgtaac
    15121 gagacaaggg tatagtgatg attcatgctg ggcacgtggt cagtcatggg gagtttatgg
    15181 tattcctttg acttatcgtc acttaaaaga cgagtcctgc tttgacttgt ttaagggtgt
    15241 gaccaattat ttcttgaatc gtctgccaaa agatcatgtg tcctattggg atttgatttt
    15301 taatgatggt agtgatcaat cacgagattc ttcagcaaca gctattgccg tctgtgggat
    15361 tcatgaaatg ctaaaacatc tcccagaggt ggatgctgac aaagatattt ataaacatgc
    15421 tatgcatgcc atgcttcgtt ccttgatcga acattatgca aatgatcaat ttacccctgg
    15481 tgggacaagt ctcctccacg gtgtgtactc atggcattca ggtaaaggag tggatgaagg
    15541 caatatctgg ggtgactact attacctaga agcccttatc cgtttctaca aagactggaa
    15601 cctatattgg taggaggaga aatatgacaa tgccaaatat tattatgacc cgtatcgatg
    15661 aacggttgat tcatggacaa ggacaacttt gggtaaaata cctaggttgt aatacggtca
    15721 ttgttgccaa tgacgaagta agcacggaca agatgcaaca aactctgatg aaaacagttg
    15781 tgccagactc agttgccatg cgtttcttcc ctttgcaaaa ggtgattgat atcattcaca
    15841 aggctaatcc tgctcaaacg atctttatcg ttgtaaagga tgtgaaggac gctttaacct
    15901 tggtagaagg tggtgtccct atcaaagaaa tcaatattgg gaacattcac aatgctactg
    15961 gtaaagagca agtgacacgc tccatcttcc tgggtgaaga ggacaaggca gccctcaagg
    16021 aattgagcca aactcatcaa gtaacattta atacgaaaac aactccaaca ggaaatgatg
    16081 gagctgttca agtcaacatt atggactata tttaaaagag gagatcgtta tgtcgattaa
    16141 tgtatttcaa gcgattttaa ttggattatg gacagctttc tgttttagtg gaatgctgtt
    16201 agggatttac accaatagat gtattgtttt gtcatttggt gtcggaatta ttctaggtga
    16261 tttgcctact gctcttgcaa tgggagctat tggtgaattg gcttatatgg gattcggtgt
    16321 tggtgctgga ggtactgttc caccaaaccc aatcggacct ggtatctttg gtaccttgat
    16381 ggctatcact agtgctggta aagtcagtcc agaagcggct cttgccctct ctactccgat
    16441 tgctgtggcg attcaattct tacaaacttt cgcctacact gtacgtgctg gtgcgcctga
    16501 aacggcgatg aagcacttga aaaaccataa tttgaagaaa ttcaagttca ctctaaatgc
    16561 aacaatttgg ttgtttgcct ttattggatt taccttgggt tgcttgggtg ccctttcaat
    16621 ggataccttg ttgaaactcg tagactacat tccaccggta ttgcttacag gtttgacagt
    16681 tgctggtaaa atgctcccag ctatcggttt tgcgatgatc ttgtcagtga tggctaagaa
    16741 agagttgatt ccctttgtct tgttgggata tgtttgtgca gcttatctaa acatcccaac
    16801 aattggtatt gcaattgtag gtactatctt tgctttgatt gaattttata acaagccaaa
    16861 aacagcggat catgtggtag aggaggaagc acacgatgac tggatctaac aaattaacaa
    16921 aacgtgatta tcttaaaacg tctttgcggg cattcttttg tcaaaatgga tttaactata
    16981 gtaactatca agggttggga tatgccaatg tgatgtatcc tgctttgaaa aaacactatg
    17041 gagaggatca ggaaggtttc taccaagcct tggaagaaaa ctgtgaattc tataatacca
    17101 acccacactt cctgcctttt attaccagct tgcatcttat aatgttggaa aatggccgtc
    17161 cggcaaaaga aacacgtagc atcaagatgg ccttgatggg accattggca ggtattgggg
    17221 attctctttc tcaattctgt ttagctccat tgttctcaac catcgcagct tcgtttgctc
    17281 aagaaggctt ggttgtcggt ccaatcttgt tcttccttgc gatgaatacg attttaacag
    17341 cgattaaatt gtcaactggt ctgtatggat acaaactagg aacaactgtg attgataaac
    17401 taagcgagca gatggcaacg atttctcgta ttgccaatat tatcggtgta accgtaattg
    17461 ctggtttggc agcgacatct gttaagatta tggtgccgat tacctttgct gcaggggaag
    17521 ttaaagcaga cgctaaacaa agtatcgtaa gtattcaggg aatgcttgat aaggttgctc
    17581 cagctcttct accagcccta tttacacttt tagtttacta cttgatcaaa gaaaagaaat
    17641 ggacaacata taaactcgtt attttaacag ttatcatcgg aattatcgga agctggctta
    17701 agattatagc ttaatggata caacattgtt ttatggaata gtgattgtct tggcagtgag
    17761 tcccctttta ctgtcaagct ttcattctat tcgtcagcaa aagttgcttc gcaaacagat
    17821 ggagcaacga caagagtatt tagcttcttt aacatctggt gatgaagtgt tgttattgtc
    17881 tggaattcat ggaaaaatca tttctatcaa agatgacttg gtctccttgc agattgcaaa
    17941 aggtgtggtc atctatgtag aaaaggaaag tgtaatggga aagacaaaag aactgctttt
    18001 taagtagttc tttttctggt aatagataat gaaagaagaa agaagacaat tttttgaaag
    18061 agtcgatgga aaccaatgtc gtgattatat cttgtcccac tgttcaaaag actatgagaa
    18121 agtcaagagt tcccttgaac gcttgatgga caatcgtttt atgtttgata gtccttggga
    18181 tatggagcct tgttcaaaaa tccatcaaat ccagccgatg gtatgggatc aagtatttga
    18241 agatgatcca gaatggtctt atatgctcaa tcgacaagaa tatctcttgc agtttatgat
    18301 agggtatctg gtagaaggag ataaggacta tattcaaaag tgcaagttct ttctatttga
    18361 ttggattgag caggtgagag aattttctcc tcaatccttg atgactagaa ccttggatac
    18421 gggtattcgt tcctttactt ggttgaaact actcttgctc ctcttgaaat ttgacttgct
    18481 agaggagaaa gaactagaga aaattttggt cagtctagaa aagcagattg actttatgaa
    18541 aagccactat cgcgccaagt acacccttag taactggggg attttacaaa caattccgat
    18601 gcttgctatc tatcatttct tttcagataa gatggaccta gaagaagctt accattttgc
    18661 ttcagaggag ttgaaacagc aaattgagac acagatttta ggagatggaa gccagtttga
    18721 acagtcgatt ctctatcatg tagaggttta taaagccttg ctggatttgt gtctcttgct
    18781 tccagatttg caagatagtt accaagagtt gctggaaaag atggcgacct atattcaaat
    18841 gatgacaggc ttagatggac ggactttggc ttttggtgat agcgattcta cagaaacgac
    18901 agaaattttg agcctgtctg ctgtggtttt gaacaaggaa gaccttctta acggtctgga
    18961 tgttaaagtc gatttgctca gcctcttgtt cctggggcga gaaaaggtca agcgactgca
    19021 ggaatttgaa aagagagctt ggcagcctaa gtccatgatc tttgaagact ctggacatgt
    19081 ctgcattaag gatgaacatc gttatctatt tttcaaaaat ggtccgctag gaagtgccca
    19141 tagccatagt gacgagaata gtttttgctt acagtatcaa ggccaaccta ttttcataga
    19201 tgctgggcgt tattcttatc gggagatata tgaacgttat ctcttaaaga gtgcttggag
    19261 tcattcgacc tgcattgtag atgggaaagc tccggaaaga atcacgggat cctgggaata
    19321 tgaatactat cctcactccc tgttttgtca ccataaagaa agggagggaa tgcattatat
    19381 tgaaggggct tattggtcag cagaacctga tttgccttat cttcacagga gaaaaatcct
    19441 catgttggta gaggatgtct ggctcttggt agatgacatc aggtgtcaag gtcagcatga
    19501 ggcgttgact cagtttatcc ttgacaagga tgtgacctat caagatggga aaatcaatca
    19561 gttgagacta tggagtgaag ttgattttga tttggaagat accatcattt ctcctaaata
    19621 caatgagctt gaaagaagta gcaaactcac caagcgccaa ttctttgaga atcagatgct
    19681 ggattatacc atcattgcgc atgagagttt tgaaatcatc cgtcattctg tctaccagac
    19741 agatgatcgt gaagtggaaa atgctctggc ttttgaagtg aaaaatgacg aaacagacaa
    19801 gctgattctg ttattaagcg aggatatttg tgtaggtgaa aaattgtgcc tcgttgacgg
    19861 aacaaaaatg cgtggaaaat gtctagtata tgataaaata aatgagagaa tgattcgctt
    19921 gcagtgctag aaataggcat tttgaatagt gaatatgtta taataagtat tagtaggagg
    19981 tgttttagat tggagaagaa actgaccata aaagacattg cggaaatggc tcagacctcg
    20041 aaaacaaccg tgtcatttta cctaaacggg aaatatgaaa aaatgtccca agagacacgt
    20101 gaaaagattg aaaaagttat tcatgaaaca aattacaaac cgagcattgt tgcgcgtagc
    20161 ttaaactcca aacgaacaaa attaatcggt gttttgatcg gtgatattac caacagtttc
    20221 tcaaaccaaa ttgttaaggg aattgaggat atcgccagcc agaatggcta ccaggtaatg
    20281 ataggaaata gtaattacag ccaagagagt gaggaccggt atattgaaag catgcttctc
    20341 ttgggagtag acggctttat tattcagccg acctctaatt tccgaaaata ttctcgtatc
    20401 atcgatgaga aaaagaagaa aatggtcttt tttgatagtc agctctatga acaccggact
    20461 agctgggtta aaaccaataa ctatgatgcc gtttatgaca tgacccagtc ctgtatcgaa
    20521 aaaggttatg agcattttct cttgattaca gcggatacga gtcgtttgag tactcggatt
    20581 gagcgggcaa gtggttttgt ggatgcttta acagatgcta atatgcgtca cgccagtcta
    20641 accattgaag ataagcatac gaatttggaa caaattaaag aatttttaca aaaagaaatc
    20701 gatcccgatg aaaaaactct ggtatttatc cctaactgtt gggccctacc tctagtcttt
    20761 accgttatca aagagttgaa ttataacttg ccgcaagttg ggttgattgg ttttgacaat
    20821 acggagtgga cttgcttttc ttctccaagt gtttcgacgc tggttcagcc ctcctttgag
    20881 gaaggacaac aggctacaaa gattttgatt gaccagattg aaggccgcaa tcaagaagaa
    20941 aggcaacaag tcttggattg tagtgtgaat tggaaagagt cgactttcta aaatgaagga
    21001 aaatgacttg caatctctgt taagaaataa aataatccca cctagaacaa gctaggtggg
    21061 attatttgcc tatgaaatga gaaattatgg gagcaagctc ctaaatcaac tgtttttgat
    21121 ctacttcttt aactacttga taaaagttat agaagtaggc caaacttgaa atgatggtta
    21181 cgactaggaa tattgaaaat ttccattgga cagggttggt taaaagttgt ggaaaggata
    21241 tgaggagaaa gaagagggct gcgttgagga caggtatccg ttttgattgt attttctcaa
    21301 gtcctttatt gagcgcagga agaaagagga gtaggagtag taaaactgta tgagaaacag
    21361 ctcctgaaat aagggcaaag aaaaggaaaa tactgataaa aacatgaatg atcagtagtc
    21421 tagctagtga tttcataagg tacctcctaa tcctggtctt ttttagctct tgcaatacga
    21481 agtgagtcga caatatgtat catcactccg aaaaagaaag ctcccagtat agttttaaaa
    21541 atatgttttg tatttagaag agaactgata aaatttggat tttcacttgt tagggtatca
    21601 atgggtggaa ttataaaaaa tattattgtt ccataaatcg aacctgcttt cagaccagga
    21661 taacgtaact gtttcttttc ttttttcata gtttcctcct aatcctcatc cggatctttc
    21721 ttagtttttg caatgcgacg ggagatgagg aactgtatgc tcgctccgaa gaagatagaa
    21781 ccgagaatgc ttgatacacc atttcttata gtgagaagag aatgaaaata gtcctgacct
    21841 tcacctatga gtataccgag aagaggagtt ataaaaaaca tccatagacc aaagaacaaa
    21901 cctgctttca gacctgggta atgtagttgc ttactttctt tctcactcag catatctgga
    21961 tcaatagctg taatccctgc ttttttcatt tggtaggtga catagccagc agcgatgagg
    22021 gcaatcacta aaatcagagg aggatagatt agagccactt cttgagggta tttataggcc
    22081 agaaggagtg gaataagatt tccgaaaatc atcagataaa agaggacgat aaagacttgg
    22141 ttcccaatac tatcggcctc acgccgtttg tattcgtcaa ggggaccaga aataccgtat
    22201 gtgcgtttga tcagtttttc agtaaaggtt tcttttttca taagtttgct ccttttttaa
    22261 aaatcttcct cccaaaagag actgttgagg tcagtttgga ggctgcgggc gagattgaga
    22321 cagagttcca gagttggatt gtacttgtcg ttttcaatca tattgatggt ctgtctcgag
    22381 acaccgatat ccttggcgag ttcgagctgg gaaataccca attccttgcg aaattctttc
    22441 acacgattca tctggtctcc tttctgaagt gtgtcgtata tatttgacta tattatattc
    22501 ttttaaacat aaagtgtcaa gtatttttga catatttttt gaagaaatat tagcgctctt
    22561 gtctgatttg tctgactagt gcaagctggt cagatttgtg gtaaaataga taagatatga
    22621 caaaagaatt tcatcatgta acggtcttac tccacgaaac gattgatatg ctcgacgtaa
    22681 agcctgacgg tatctacgtt gatgcgactt tgggtggagc aggccatagc gagtatttat
    22741 taagtaaatt aagtgaaaaa ggccatctct atgcctttga ccaggatcag aatgccattg
    22801 acaatgcgca acaacgcttg gcaccctaca ttgaaaaggg aatggtgact tttatcaagg
    22861 ataacttccg tcatttgcag gcacgtttgc gcgaagctgg tgttcaggaa attgatggca
    22921 tttgttatga cttgggagtg tctagtcctc aattggacca gcgtgagaga ggtttttctt
    22981 ataagaagga tgcgccactg gacatgcgca tgaatcagga agctagtcta acagcctatg
    23041 aagtggtgaa ccactatgac tatcatgact tgattcgtat tttcttcaag tatggagagg
    23101 acaaattctc taaacagatt gcgcgtaaga ttgagcaagc tcgagaagtc aaacctatcg
    23161 agactacgac tgaattggca gaaattatca agtcggccaa acctgccaag gaacttaaga
    23221 agaagggtca tcctgccaag cagattttcc aggctattcg aattgaagtc aatgatgaac
    23281 tgggagcggc agatgagtcc atccagcagg ctatggagat gttggctctg gatggtagaa
    23341 tttcagtgat tacctttcat tccttggaag accgcttgac caagcaattg ttcaaggaag
    23401 cttcaacggt tgaagttccc aaaggtttgc ctttcatccc agatgatctc aagcctaaga
    23461 tggaattggt gtcccgtaag ccaatcttgc caagtgcaga agaattagaa gccaataacc
    23521 gctcgcactc agccaagttg cgcgtggcca gaaaaattca caagtaagag gaaaaaagat
    23581 ggcagaaaga atggaaaaaa caggtcaaat actacagatg caacttaaac ggttttcgcg
    23641 tgtggaaaaa gctttttact tttccattgc tgtaaccact cttattgtag ccattagtat
    23701 tatttttatg cagaccaagc tcttgcaagt gcagaatgat ttgacaaaaa tcaatgcgca
    23761 gatagaagaa aagaagaccg aattggacga tgccaagcaa gaggtcaatg aactattacg
    23821 tgcagaacgt ttgaaagaaa ttgccaattc acacgatttg caattaaaca atgaaaatat
    23881 tcgaatagcg gagtaagata tgaagtggac aaaaaaagta atccgttatg cgaccaaaaa
    23941 tcggaaatcg ccggctgaaa acagacgcag agttggaaaa agtctgagtt tattatctgt
    24001 ctttgttttt gccgtttttt tagtcaattt tgcggtcatt attgggacgg gcactcgctt
    24061 tggaacggat ttagcgaagg aagctaagaa ggttcatcaa accacccgta cagttcctgc
    24121 caaacgtggg actatttatg accgaaatgg agtcccgatt gctgaggatg cgacatctta
    24181 taatgtctat gcggtcattg atgagaacta taagtcagca acgggtaaga ttctttacgt
    24241 agaaaaaaca caatttaaca aggttgcaga ggtctttcat aagtatctgg acatggaaga
    24301 atcctatgta agagagcaac tctcgcaacc taatctcaag caagtttcct ttggttcgaa
    24361 gggcaatggg attacctatg ccaatatgat ggctatcaaa aaagagttgg aaactgcaga
    24421 ggtcaagggg attgatttta caaccagtcc caatcgtagt tacccaaacg gacaatttgc
    24481 ttctagtttt atcggactag ctcagctcca tgaaaatgaa gatgggagca agagtttgct
    24541 gggaacttct gggatggaga gttccttgaa cagtattctt gcagggaaag acggtattat
    24601 tacctatgaa aaagatcgtc tgggtaatat tgtccccgga acggaacaag tttcccaaca
    24661 aacggtagat ggcaaggatg tttatacaac tatttccagc acccttcagt ccttcatgga
    24721 gacccagatg aatgcctttc aagaaaaagt aaaaggcaag tatatgacgg ctaccttggt
    24781 cagtgctaaa acaggggaaa ttcttgcaac aacgcaacgg ccgaccttcg atgctgatac
    24841 taaggagggg ctgactaagg actttgtttg gcgtgatatc ctctatcaaa gtaactatga
    24901 accagggtca accatgaagg tcatgactct cgctgctgct attgataata acactttccc
    24961 aggaggagaa gttttcaata gtagtgagtt aaaagtagca gatgctacta tccgagattg
    25021 ggacgtcaat gaaggattaa ctggcggagg aatgatgacc ttttctcaag gtttcgcgca
    25081 ctcaagtaac gttgggatga cgcttcttga gcaaaagatg ggagatgcta cctggcttga
    25141 ttatctcaat cgctttaaat ttggtattcc gactcgtttt ggcttgacgg atgaatatgc
    25201 aggtcaactt ccagctgaca atattgtcaa tatcgctcag agttcatttg gacaagggat
    25261 ttcagtaact caaacacaaa tgattcgtgc ctttacagcc attgccaatg atggcgtcat
    25321 gttggagcct aaatttatta cggccttgta tgacccaaat aaccaatctg ttcgtaaatc
    25381 tcaaaaagaa attgtaggga atcctgtttc taaggatgcg gcaagtcaaa ctcggactca
    25441 tatggtctta gtaggaacgg atcctagata tggaactatg tataatcata gtacaggaaa
    25501 agcaactgtc aatgttccag gtcaaaatgt agccctcaag tctggtacag ccgaaatcgc
    25561 tgacgagaaa aatggaggct acttggttgg ttctaccaac aacattttct cagttgtggc
    25621 tatgaaccct gccgaaaatc ctgattttat cttgtatgtg acggtccaac aacctgaaca
    25681 ttattcaggt atccagttgg gagaatttgc caatcctatc ttggaaagag cagtggccat
    25741 gaaagattcc cttaacctcc aatctaccgc taaaacgtta gatcaggtaa ccaatcaaag
    25801 cgcttatgcc atgcctagca tcaaggatat ttcacccggt gatttggcgg aagccttacg
    25861 tcgcaatatt gtgcaaccaa tcgttgtagg aacaggaaca aagattaaag aatcatctgt
    25921 agaagaagga agcaatcttg ctcctaacca gcaagttctt ctcttatctg ataaagcaga
    25981 ggaagttcca gatatgtatg gttggacaaa agcaaccgca gaagcttttt ctaagtggtt
    26041 aaatatagaa cttgtatttg aaggttcggg ctctactgtt cagaagcaag atgttcgtgc
    26101 taatacagca atcaaggaca ttaaaaaaat tacattaact ttaggagact aatatgttta
    26161 tttccatcag tgctggaatt gtgacatttt tactaacttt agtaggaatt ccggccttta
    26221 tcaaatttta tagaaaggcg caaattacag gccagcagat gcatgaggat gtcaaacagc
    26281 atcaggcaaa agctgggact cctacaatgg gaggtttggt tttcttaatt gcttctgttt
    26341 tggttgcctt cttttttgcc ctatttagta gccaattcag caataatgta ggaatgattt
    26401 tgttcatctt ggtcctttat ggacttgtcg gatttttaga tgactttctc aaggtctttc
    26461 gtaaaatcaa tgaggggctg aatcctaagc aaaaattggc tcttcagctt ttaggtgggg
    26521 tcgttttcta ccttttctat gagcgtggtg gcgatatgct ttcagtcttt ggttaccaag
    26581 tgcatctagg gattttctat attctttttg cccttttctg gctagtcggt ttttcaaatg
    26641 cagtcaactt gacagacgga attgatggtc tggctagtat ttctgttgtg attagtttgt
    26701 ctgcctatgg agttattgcc tatgtgcaag gtcagatgga tatccttcta gtgattcttg
    26761 ccatgattgg tggtctgctt ggtttcttcg tctttaacca taagcctgct aaggtcttta
    26821 tgggtgatgt gggaagtttg gccctaggtg ggatgctggc agctatctct atggctctcc
    26881 accaagaatg gactctcttg attatcggaa ttgtgtatgt ttttgaaaca acttctgtta
    26941 tgatgcaagt cagttatttc aaactgacag gtggtaaacg tattttccgt atgacgcctg
    27001 tacatcacca ttttgagctt gggggattgt ctggtaaagg aaatccttgg agcgagtgga
    27061 aggttgactt cttcttttgg ggagtgggac ttctagcaag tctcctgacc ctcgcaattt
    27121 tatatttgat gtaagaatgg caccctgatg tttcagggtg tttttgtgtt taaatacaca
    27181 atgaaaatca aagaacaaac tagaaagcta actttaggct gctcaaaata tagtagattg
    27241 aaactagaat agtacacatc tacttctaaa atattgttag aaatcgattt gactgtcctg
    27301 attgatttgt cctgttctta tttcgtttta atatacagtt ttgagatggt tgatagaact
    27361 gacgaagtca gctcaaaaca cggttttgag gttgtagata aggagaagct gatgtggttt
    27421 gaagaggttt tcgaagagtg taaaaaaata ttggtcagtt aaagtcaaaa ctcttgacct
    27481 tttctgacca atgtagtata ttatgaacgt aaggtaaatg aaagccttac tagaacactt
    27541 atttaaagta aaatagaaag aggtgggtct atgtttcatc tagaaatctt cagaagtaaa
    27601 gatagtctac tcctgcttga aaaagaaaaa ccagaaatag tacgtagggt agcgatctag
    27661 ctagtctaaa ttttttaaaa caatggtcaa agatagtcaa tatcagtaat cataactaag
    27721 taaacaaaaa gaggtaaaga atatgaataa caactttaat aattttaata acatggatga
    27781 tttatttaac caattgatgg gtggtatgcg aggatacagt tctgaaaatc gccgttactt
    27841 aattaatgga cgcgaagtca cacctgagga atttgctcac tatcgtgcga ctggtcaatt
    27901 accaggaaat gcagaaactg atgtgcaaat gccacaacag gcatcaggta tgaaacaaga
    27961 cggtgtcctt gcaaaactag gtcgaaactt aacagcagaa gcgcgtgagg gcaagttgga
    28021 tcctgttatc ggacgaaaca aggaaattca agaaacatct gaaatcctct cacgccgcac
    28081 caagaacaat cctgttttgg tcggagatgc aggtgttggt aagacagcag ttgtcgaagg
    28141 tctagcgcaa gccattgtga acggagatgt tcctgctgct atcaagaaca aggaaattat
    28201 ttctattgat atctcaggtc ttgaggctgg tactcaatac cgtggtagct ttgaagaaaa
    28261 tgtccaaaac ttagtcaatg aagtgaaaga agcagggaat attatcctct tctttgatga
    28321 aattcaccaa attcttggtg ctggtagcac tggtggagac agtggttcta aaggacttgc
    28381 ggatattctc aagccagctc tctctcgtgg agaattgaca gtgattgggg caacaactca
    28441 agacgaatac cgtaacacca tcttgaagaa tgctgctctt gctcgtcgtt tcaacgaagt
    28501 gaaggtcaat gctccttcgg cagagaatac ttttaaaatt cttcaaggaa ttcgtgacct
    28561 ctatcaacaa caccacaatg tcatcttgcc agacgaagtc ttgaaagcag cggtggatta
    28621 ttctgttcaa tacattcctc aacgtagctt gccagataag gctattgacc ttgtcgatgt
    28681 aacggctgct cacttggcgg ctcaacatcc agtaacagat gtgcatgctg ttgaacgaga
    28741 aatcgaaacg gaaaaagaca agcaagaaaa agcagttgaa gcagaagatt ttgaagcagc
    28801 tctaaactat aaaacacgca ttgcagaatt ggaaaagaaa atcgaaaacc acacagaaga
    28861 tatgaaagtg actgcaagtg tcaacgatgt ggctgaatct gtggaacgaa tgacaggtat
    28921 cccagtatcg caaatgggag cttcagatat cgaacgtttg aaagatatgg cccatcgctt
    28981 gcaagacaag gtgattggtc aagataaggc cgtagaagct gtagctcgtg ctatccgtcg
    29041 taaccgtgct ggttttgatg aaggaaatcg cccaatcggc agcttcctct ttgtagggtc
    29101 tactggggtt ggtaagacgg agcttgctaa gcaattggca ctcgatatgt ttggaaccca
    29161 ggatgcgatt atccgtttgg atatgtctga atacagtgac cgtacagctg tttctaagct
    29221 aattggtaca acagcaggct atgtgggtta tgatgacaat agcaatacct taacagaacg
    29281 tgttcgtcgc aatccatact ctatcattct cttggatgaa attgaaaagg ctgatcctca
    29341 agttattacc cttctcctcc aagttctaga tgatggtcgt ttgacagatg gtcaaggaaa
    29401 tacagtaaac ttcaagaaca ctgtcattat tgcgacctca aatgctggat ttggctatga
    29461 agccaacttg acagaagatg cggataaacc agaattgatg gaccgtttga aacccttctt
    29521 ccgtccagaa ttcctcaacc gctttaatgc agtcatcgag ttctcgcact tgactaagga
    29581 agacctttct aagattgtag atttgatgtt ggctgaagtt aaccaaacct tggctaagaa
    29641 agacattgac ttggtagtta gtcaagcggc taaagattat atcacagaag aaggttacga
    29701 cgaagtcatg ggggttcgtc ctctccgtcg cgtggttgaa caagaaattc gtgataaggt
    29761 gacagacttc cacttagatc atttagatgc taaacatctg gaagcagata tggaagatgg
    29821 cgttttggtt attcgtgaga aagcctaaga tagaattttg aggataaaaa agaaggagcc
    29881 agctgaaaaa aactggttcc tttttaggta cgacaggcat gtcgtatagt agaagtgtat
    29941 tattccagtt tcaat
//
LOCUS       DAVAGB010000025        26513 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVAGB010000025 DAVAGB010000000
VERSION     DAVAGB010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26513
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.025"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            291..1772
                     /locus_tag="VQO19_001224"
     CDS             291..1772
                     /locus_tag="VQO19_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET1349498.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            2134..3135
                     /locus_tag="VQO19_001225"
     CDS             2134..3135
                     /locus_tag="VQO19_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET1349499.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3285..4202
                     /locus_tag="VQO19_001226"
     CDS             3285..4202
                     /locus_tag="VQO19_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET1349500.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4213..5103
                     /locus_tag="VQO19_001227"
     CDS             4213..5103
                     /locus_tag="VQO19_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET1349501.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            5132..6748
                     /locus_tag="VQO19_001228"
     CDS             5132..6748
                     /locus_tag="VQO19_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET1349502.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAYIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6758..8077
                     /locus_tag="VQO19_001229"
     CDS             6758..8077
                     /locus_tag="VQO19_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET1349503.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKIEQNPVATGADLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            8473..8904
                     /locus_tag="VQO19_001230"
     CDS             8473..8904
                     /locus_tag="VQO19_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349504.1"
                     /translation="MKNNERLGIKLSRDSVLGLREVRRLYLGSSDIPVPDSYVIEVAY
                     KQISNEIDIIDWVELNKSKIKISEISESVDIDATSLRTTLTLDTLVYEGMRDIQLKLR
                     ELTKGRVFFSFVVKLVLFASILKKKGLLEKFQESVNQVLTF"
     gene            9136..9687
                     /locus_tag="VQO19_001231"
     CDS             9136..9687
                     /locus_tag="VQO19_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000810873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349505.1"
                     /translation="MKQKQPIVARTKQHTFEELIQDQKLERLAKFSPDLVGRYGFTAS
                     CASSFANLIKEAYGGKNLNVVYASRMLALWNIACSCYHKADGYSLADALFSDKKICLD
                     YFYYHNNTSDIITLDMIEDVKKNYLQLVTTATSDNMSVIEFEMEKESDLYYFIKATLG
                     SSFSRMHYSVLVKALAGALAKNI"
     gene            9747..9968
                     /locus_tag="VQO19_001232"
     CDS             9747..9968
                     /locus_tag="VQO19_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349506.1"
                     /translation="MFKNFCQNAFISLYFIVSALGGFSARLEFRSFSPYQSMKVALLL
                     GVILILLQLPIMFAKLLEALKIKKGETHE"
     gene            10184..11497
                     /locus_tag="VQO19_001233"
     CDS             10184..11497
                     /locus_tag="VQO19_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HET1349507.1"
                     /translation="MFKIKQTASLSEHYFLNTSKLRSIRWFTIGFLSILSFSSSILFK
                     GWFLQMITLSVELIIILYIERKIKGWAQQIEPLLIVRENLLFMLRRNSFLFTATKDGA
                     ILRSAKFNYQLNDVSIVVHALKSGDEFTKEMETLDVFLSSTLGISLSSKEIYATHVEY
                     VFVYKQPERLYVTSLPLEDDSLKIKIYDDFVIDLRKNFSMLISGASGSGKSFFTYYYL
                     TRFISQTVNGKHAKIYVIDPKFSDIYKLCEFSGFPVENYGTTNEDAFRILRQYIKELD
                     RRMLIYNQSNLFNSIGIDLGFPPLLLVIEEYSSLVSSMDSKAKKDFENMVAIVAQKAR
                     SLSMGVCIVMQQPRSDSLSTNIREQLVNAIFLGAPTRESSQMMFGTTDVPNVKKDKGV
                     GLCSTDRESPKEFQAPIFNRDVFETILPVWECAAKNYMKDEDENV"
     gene            11824..12084
                     /locus_tag="VQO19_001234"
     CDS             11824..12084
                     /locus_tag="VQO19_001234"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349508.1"
                     /translation="MKETVVVLAISTKKERGWIKVSTLNDCWSDLGMHFDKSKFGAVF
                     SAPGLYEVEVINNASFGQNAQYEVIQSRKLGTFAELIEQVKN"
     gene            12213..13256
                     /locus_tag="VQO19_001235"
     CDS             12213..13256
                     /locus_tag="VQO19_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HET1349509.1"
                     /translation="MNKEVLNRAPSNSPITIHQMSNKSYSKFQEEVSLKYGFIGLKLD
                     KLSLTAEVSEEFHSEILSGNFTLYDYFGVVEPNLNRNGELASYKGQFFNDEKENWYIE
                     YTPVASIKMNKRPLKIEFTPSKVSKKNFLIVFHRMFPYMFNIAISTFHLAYDFERDLS
                     ALRVNWPKVMYRPIYKGMKLETMDFGAPKGNYHLTAYNKLKERMDSGDMAEIEIYQQY
                     DNLWRIEYKFYNEGNIKKELKNGLPFLAKIPVYIENFKGLEFNNLGVNEKIYLFALRN
                     KPELFAESDKRTVAKYKKLAESISEVNLNVFFQNALDFVEIFNQEPCLINFFEFMNSM
                     LQGDIPKLTINQE"
     gene            13272..13454
                     /locus_tag="VQO19_001236"
     CDS             13272..13454
                     /locus_tag="VQO19_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HET1349510.1"
                     /translation="MKDTISNKDLISMGYRPSTANAIIHQARELLVSRGYTFYNRKRL
                     MVVPKSVVKELLGMEL"
     gene            13456..14583
                     /locus_tag="VQO19_001237"
     CDS             13456..14583
                     /locus_tag="VQO19_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET1349511.1"
                     /translation="MAYIEYRQRGKKKLWSFSIRERSKSLLHKSGFKTKREAKIEAEK
                     VLHKLNTGSVLSSSMTLSELYNEWLDLKILPSNRSVVTKKKYLMRKKVIERLFGNKPV
                     SQIKPSEYQKIMNEYGETVSRNFLGRLNSSIQASIQMAIADKVIIEDFTAYVELFSSK
                     SGQKVEEKYLHTESDYQKVLVYLKNKFDYQKSIVPYVIYFLFKTGMRFSELIALTWDE
                     VDELNEQLKTYRRYNTAIHKFTPPKNNTSIRLVPITSDMLSLLKTLKILQLKTNKELN
                     IDNENNLIFQHFGYVYDVPDIATVNKAIKVMLKELQIFPLITTKGARHTYGSYLWHNN
                     IDLGVIAKILGHKDISMLIDVYGHTLEEKISEEFMAVKSLL"
     gene            complement(14664..14736)
                     /locus_tag="VQO19_001238"
     tRNA            complement(14664..14736)
                     /locus_tag="VQO19_001238"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14701..14703),aa:Lys,seq:ctt)
     gene            complement(15001..16272)
                     /locus_tag="VQO19_001239"
     CDS             complement(15001..16272)
                     /locus_tag="VQO19_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HET1349512.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKNSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFNFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDHLRKI"
     gene            16542..16781
                     /locus_tag="VQO19_001240"
     CDS             16542..16781
                     /locus_tag="VQO19_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349513.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            16946..17125
                     /locus_tag="VQO19_001241"
     CDS             16946..17125
                     /locus_tag="VQO19_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349514.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            17268..17441
                     /locus_tag="VQO19_001242"
     CDS             17268..17441
                     /locus_tag="VQO19_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HET1349515.1"
                     /translation="MTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITILHGELN
                     KYTERGIGKQAGL"
     gene            17478..17930
                     /locus_tag="VQO19_001243"
     CDS             17478..17930
                     /locus_tag="VQO19_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HET1349516.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            18221..18691
                     /locus_tag="VQO19_001244"
     CDS             18221..18691
                     /locus_tag="VQO19_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HET1349517.1"
                     /translation="MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            18710..19798
                     /locus_tag="VQO19_001245"
     CDS             18710..19798
                     /locus_tag="VQO19_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HET1349518.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            19779..20207
                     /locus_tag="VQO19_001246"
     CDS             19779..20207
                     /locus_tag="VQO19_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET1349519.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            20342..21295
                     /locus_tag="VQO19_001247"
     CDS             20342..21295
                     /locus_tag="VQO19_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HET1349520.1"
                     /translation="MMETWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNV
                     DRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTAL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKM
                     SIFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNP
                     GMENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDK
                     WDMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            21297..22040
                     /locus_tag="VQO19_001248"
     CDS             21297..22040
                     /locus_tag="VQO19_001248"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HET1349521.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLTQLDQ
                     FDSIIVAYEESGKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            22051..23847
                     /gene="pepF"
                     /locus_tag="VQO19_001249"
     CDS             22051..23847
                     /gene="pepF"
                     /locus_tag="VQO19_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET1349522.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            24094..24885
                     /locus_tag="VQO19_001250"
     CDS             24094..24885
                     /locus_tag="VQO19_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HET1349523.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEGVSSDVGLDKEIDKVGLPTLERSFRALVYANLLYADANQ
                     QSVFYQGLQLEIRNVFSNQGLHYLSKEKDTTGFSSQYGWVHAFAHGADLLTEVVCHPD
                     FPINRIHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFSKFSNFRSCLVEVYVQLDQRNSLQDELKEAIQSFQY"
     gene            24996..25664
                     /locus_tag="VQO19_001251"
     CDS             24996..25664
                     /locus_tag="VQO19_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HET1349524.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGFDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGPIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(25833..25922)
                     /locus_tag="VQO19_001252"
                     /pseudo
     CDS             complement(25833..25922)
                     /locus_tag="VQO19_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(25919..26245)
                     /gene="queF"
                     /locus_tag="VQO19_001253"
                     /pseudo
     CDS             complement(25919..26245)
                     /gene="queF"
                     /locus_tag="VQO19_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000082574.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="preQ(1) synthase"
     gene            complement(26240..26389)
                     /locus_tag="VQO19_001254"
                     /pseudo
     CDS             complement(26240..26389)
                     /locus_tag="VQO19_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730462.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine synthase"
BASE COUNT         8316 a         4320 c         5599 g         8278 t
ORIGIN      
        1 tcaattattt cgattgttat tattatataa ttttaaaaaa tcaaattctt taattgttgc
       61 tattatataa tttttaaaat taaaaatata atctttagac ttgaatttga ttctgtattc
      121 acgccctcaa tagacggtaa aataagaaaa ttgtttatat attgtctccg tagtgttatt
      181 atacgaaata aaagatttta ggaaaagtcg ttatatcatg ctatacctat tctttgtggt
      241 ataattgcaa gaggtttaat ccgataattt ataaagagag aaagatattc atgagagatt
      301 tattatctaa aaaaagtcat aggcaattag aattattaga attattattt gaacataaac
      361 gttggtttca tcgttctgaa ctagcagagt tattaaattg tacagaacgt gcagtcaaag
      421 atgatctatc ccatgttaaa tctgcttttc ctgacttgat ttttcattct tctactaatg
      481 gtatacgcat tattaatacc gatgatagtg atattgaaat ggtttaccat catttcttta
      541 aacattcaac tcatttttcg attttagaat tcatcttctt taatgaaggt tgtcaagctg
      601 agagtatttg taaagaattt tatatcagtt catcttcgct ctatcgtatt attagccaaa
      661 tcaataaagt gattaaaagg caatttcaat ttgaagttag tctgacccct gttcaaatca
      721 ttggaaatga gagagacatt cgttactttt ttgcacaata tttttcagaa aaatattatt
      781 tcctagaatg gccatttgaa aatttttcat cagagccact atctcaattg ttagaattgg
      841 tttataagga aacaagcttt ccaatgaatt tgtcaacgca tagaatgcta aagttgctcc
      901 tagttacgaa cctatataga ataaagtttg gtcattttat ggaagtagat aaagattctt
      961 ttaacgacca aagtttggat tttttaatgc aggcagaagg aatagaaggt gttgctcaga
     1021 gttttgaatc agaatacaat atctctttag atgaagaagt tgtttgccaa ttatttgtgt
     1081 cttactttca aaaaatgttt ttcatagatg aaagtctctt tatgaaatgc gtaaaaaagg
     1141 atagttatgt tgaaaaatct taccatctat tgagtgattt tattgatcag atttcagtca
     1201 agtatcagat tgaaatggag aataaggata atctgatttg gcatctgcat aataccgcac
     1261 atctgtatcg tcaagagttg tttactgagt ttattttatt tgatcaaaaa gggaatacaa
     1321 tcaggaactt tcaaaatatt tttccaaaat ttgtttcaga tataaaaaaa gagctttctc
     1381 actatttaga gactcttgag gtttgttcta gttcaatgat ggtaaatcat ctatcttata
     1441 ccttcatcac tcataccaaa catttggtga ttaatttgct acaaaatcag cctaaactaa
     1501 aggttttagt tatgagtaat tttgatcagt atcatgcaaa attcgttgca gagacacttt
     1561 cttattattg tagcaataat tttgaactgg aagtttggac cgaattagaa ttatcaaagg
     1621 aatctttaga agattcacct tatgatatca ttatttctaa ttttattatt cctcctattg
     1681 aaaataagag actcatctat tcaaataata taaacacggt ctcactcata tacttgttaa
     1741 atgccatgat gtttattcga ttagatgagt aaccaaaaat aacaaaaaaa cgctatttcg
     1801 cgtttgaact gtacctcaaa agttagacag aaaaagtcta attttggggg tgtttttgtt
     1861 aagaaaagac cttcaatcat ttaagcaaaa tgtacatcta gatttatagc catctaaaac
     1921 tcttgctttt tttatagaag atacgaaaaa agccatgaaa ccaaggcttt tcctgtttta
     1981 tgtagatgtt tacacatgaa aattgaagta ttttcaaaag ctaattggag tgattttatt
     2041 catgatggga taaatgatct ggccaaaaat gattgagaaa tagttgctta aaaagcattt
     2101 gcatgatact atatattgaa aggaggtgat aatatggtag aacaaagaaa atcaattacc
     2161 atgaaagatg ttgctttaga agcaggagtt agtgttggaa ctgtttcacg tgtaattaat
     2221 aaagaaaaag gcattaaaga agtaactttg aaaaaagtgg aacaagcgat taaaactttg
     2281 aattacattc cagattacta cgctagagga atgaaaaaaa atcgaacaga aacgattgca
     2341 atcattgtac caagtatctg gcatcccttc ttttcagaat ttgctatgca tgtggaaaat
     2401 gaagtctata agagaaataa caaattactc ttatgttcta tcaatggtac aaatagagag
     2461 caagactatc tggagatgtt gcgtcataat aaagttgatg gagtggttgc cattacctat
     2521 agtccaattg aacattactt gacgtcagga attccctttg ttagtattga ccgcacatac
     2581 tcagatattg ccattccttg tgtttcatca gataatgatg caggtggaag agaagcagct
     2641 aaacaattaa ttagtaaagg atgtcagcat ttagcctttg tgggcggaca taatacaacc
     2701 attaatgaaa ccaaacgtcg tagaatttca tttgaaaagt atgtccaaga gcataaaata
     2761 cctcttagta tttttgattt ggatgagaca gttactgact attatggaaa gctagagagt
     2821 ttcttggaag aaaattcttc tatagatgga atttttacaa tcaacgattt tacagctttg
     2881 gatgtgattg aaatactaga aaaaaatggc aaacgtattc ctcatgatgt ccaaattatt
     2941 ggatacgatg gaattaaaat ggctggagat agagattatc tactttcaac tattgaacaa
     3001 ccattggaag aaatggcaaa agaagcggtt cgtattttgt ttgatataat tgatggaaag
     3061 actgttaatt tgcagacaat cctaccagta aaatttgttg aaggaaaaac aacaaaaaat
     3121 gaaaataagt cttgacagaa agcgctatca atgatagaat gaattcagat aaaaagattt
     3181 atttttaaaa caaaaatgaa acgtttcaaa aaagaaataa agagacagcg ccaagcgcta
     3241 tcttttctag aaaaaaatga aacgtttcaa aaaaggaggt tgctatgaat agcaaagcga
     3301 agcaagtttc tctttgggaa agaatcaaga aacaaaaact cttgttattg atgactgtcc
     3361 ccggtttagt tttaaccttt atctttaaat acatccctat gtatggggtt ttaatcgcat
     3421 ttaaagatta caatccttta aaaggaattt tagggagtga ttggattggt ttttctgagt
     3481 ttacaaaatt catatcctct cccaactttg gtatcttgtt agccaacaca ttaaaattaa
     3541 gtatctatgg tttattgctt ggctttttac caccaatcat tctcgcgatt atgctcaatc
     3601 aactcttgag tgaaaaagtc aaaaaacgaa ttcagctcat tttatacgca ccaaacttta
     3661 tctcagtcgt tgttattgtc ggtatgattt tcctcttctt ttcagtggga ggaccaatca
     3721 acaattttct ttctatgttt ggaatgaagg ctgacttctt gacaaatcca gacttcttta
     3781 gacctttata catctttagt ggtatctggc aaggaatggg ctgggcttca acgctctaca
     3841 cggcaacatt ggtaaatgta gatccagcct tagtagaagc agcccgactg gatggagcca
     3901 atatcttcca acgaatctgg cacattgata ttccagctct taagcctatt atggttatcc
     3961 aatttgtttt agctgcaggt ggaattatga atgtcggata tgaaaaagca ttcttgatgc
     4021 agacatcgtt aaatttgcca acttctgaaa ttatctcgac atatgtctat aaagttggtc
     4081 ttgtatcagg agactattct tactcaacag cggttggttt gtttaatgca gtgattaacg
     4141 tagtattgct tgttgcagtt aaccaaatcg ttaaacgcat gaataatggt gaaggaattt
     4201 aaggaggaaa gtatgaaaaa ttcgattatg gatacaaaat ttgatagacg tatcttactc
     4261 ttaaataaaa tcattattgt ctttatcgtt ttgatgactt tgcttccttt actttatatc
     4321 gtcgtagcat cctttatgga tcctaaggtt ctggttagta gagggattag ctttaatcca
     4381 gccgattgga ctgtagaagg ttaccagcgt gtattcagtg accaatctat tctaagaggt
     4441 tttatcaatt ctctactata ctcttttgga tttgcagctt taacagtctt gctatctgtg
     4501 tttacagctt atcctctttc taagaaagac ttggttggac gtcgttggat taactacttc
     4561 ttgattgtaa ctatgttctt tggtggtggt ttagtcccaa cttacttgct cgtaaaagaa
     4621 ttgggaatgc tcaatactcc atgggctatc attgttccag gtgctgttaa cgtttggaat
     4681 attattcttg ctagggccta tttccaagga ttgcctgaag aattagttga agctgctgtc
     4741 attgatggtg caaatgattt acagattttc ttcaaaatca tgcttcctct tgcaaaacca
     4801 attatgtttg ttctcttcct ttatgctttt gtaggacagt ggaactcata ctttgatgca
     4861 atgatttata tcaaggatcc aaacttggaa ccattacaac ttgtacttcg taaaattctc
     4921 attcagagcc aaccaggtca agacatgatt ggagcacaag cggctatgaa tgaaatgaaa
     4981 cgtttagctg aattgattaa atacgcaact attgtcattt ccagcttgcc attgattgtt
     5041 atgtatccat tcttccaaaa atactttgat aaaggaatta tggctggttc acttaaagga
     5101 taaaaaaaga aaaaataaaa ggagttttct catgaaattc aaaacattct caaaatcagc
     5161 agttttgttg acagctagtt tagcagtact tgcagcctgt ggctcaaaaa atacagcttc
     5221 aagtccagat tataagttgg aaggtgtaac attcccgctt caagaaaaga aaacattgaa
     5281 gtttatgaca gccagttcac cgttatctcc taaagaccca aatgaaaagt taattttgca
     5341 acgtttggag aaggaaactg gcgttcatat tgactggacc aactaccaat ccgactttgc
     5401 agaaaaacgt aacttggata tttctagtgg tgatttacca gatgctatcc acaacgacgg
     5461 agcttcagat gtggacttga tgaactgggc taaaaaaggt gttattattc cagttgaaga
     5521 tttgattgat aaatacatgc caaatcttaa gaaaattttg gatgagaaac cagagtacaa
     5581 ggccttgatg acagcacctg atgggcacat ttactcattt ccatggattg aagagcttgg
     5641 agatggtaaa gagtctattc acagtgtcaa cgatatggct tggattaaca aagattggct
     5701 taagaaactt ggtcttgaaa tgccaaaaac tactgatgat ttgattaaag tcctagaagc
     5761 tttcaaaaac ggggatccaa atggaaatgg agaggctgat gaaattccat tttcatttat
     5821 tagtggtaac ggaaacgaag attttaaatt cctatttgct gcatttggta taggggataa
     5881 cgatgatcat ttagtagtag gaaatgatgg caaagttgac ttcacagcag ataacgataa
     5941 ctataaagaa ggtgtcaaat ttatccgtca attgcaagaa aaaggcctga ttgataaaga
     6001 agctttcgaa catgattgga atagttacat tgctaaaggt catgatcaga aatttggtgt
     6061 ttactttaca tgggataaga ataatgttac tggaagtaac gaaagttatg atgttttacc
     6121 agtacttgct ggaccaagtg gtcaaaaaca cgtagctcgt acaaacggta tgggatttgc
     6181 acgtgacaag atggttatta ccagtgtaaa caaaaaccta gaattgacag ctaaatggat
     6241 tgatgcacaa tacgctccac tccaatctgt gcaaaataac tggggaactt acggagatga
     6301 caaacaacaa aacatctttg aattggatca agcgtcaaat agtctaaaac acttaccact
     6361 aaacggaact gcaccagcag aacttcgtca aaagactgaa gtaggaggac cactagctat
     6421 cctagattca tactatggta aagtaacaac catgcctgat gatgccaaat ggcgtttgga
     6481 tcttatcaaa gaatattatg ttccttacat gagcaatgac aataactatc caagagtctt
     6541 tatgacacag gaagatttgg acaagattgc ctatatcgaa gcagatatga atgactatat
     6601 ctaccgtaaa cgtgctgaat ggattgtaaa tggcaatatt gatactgagt gggatgatta
     6661 caagaaagaa cttgaaaaat acggactttc tgattacctc gctattaaac aaaaatacta
     6721 cgaccaatac caagcaaaca aaaactagag gttgattatg ggagataaga aatacacagt
     6781 agaaaaagcc aatcgtttta tagcagaaaa taaacatctc gttaatactc aatataagcc
     6841 tgaagaacat ttttcagctg agattggttg gatcaatgat ccaaatggat ttgtttattt
     6901 tcgtggagaa taccatctct tttatcaatt ctatccatat gatagtgttt ggggacctat
     6961 gcactgggga catgctaaaa gtaaggactt ggtgacttgg gagcacttgc cagtggcact
     7021 tgctcctgat caagattatg accgaaatgg ttgtttctca ggctctgcca ttgtcaagga
     7081 tgatcgcctc tggctcatgt acactgggca tatcgaagaa aaaaccggtg tccgccaagt
     7141 gcaaaatatg gcattttcag acgacgggat tcactttgaa aagattgaac aaaatccagt
     7201 tgcaacagga gcagacttgc cagatgagtt gattgctgct gatttccgtg atccaaaact
     7261 ctttgaaaaa gatggacgct attactccgt agtagctgcc aaacacaagg ataatgtggg
     7321 ctgtatcgtt ctactagggt ccgataacct agtagaatgg cagttcgaat ccatcttttt
     7381 aaaaggggta gaacaccaag ggtttatgtg ggaatgccca gattacttcg agttagatgg
     7441 gaaagattgc cttattatgt cacccatgcg ttatcagcgt gagggagact catatcataa
     7501 catcaactca tcgcttttgt tcacgggtaa ggtagattgg agagaaaaac gttttatccc
     7561 agaatcagtt caagaaattg atcatggcca agacttctat gcgcctcaaa cattgttgga
     7621 cgatcaaaat cgtcgtatcc tgattgcttg gatgcagaca tgggggcgta cccttccaac
     7681 ccatgaccaa gaacacaaat gggcatgtgc catgacttta cctagaattc taagattgga
     7741 agatggcaaa ctgagacaat tccctgttaa aaaaggccaa tatcaaatcc aaatagataa
     7801 agattgtcat taccacttag gaaatgatat agattatctt gaatttggtt atgacagtaa
     7861 tgcgcagcaa gtttacattg atcgtagcca tcttattcaa aaaattctag gtgaagaaga
     7921 acaggacact agtcgacggt atgtagatat tgaagctaaa gaattggaag ttgttctaga
     7981 taaaaattcc atcgagattt ttgtcaatca aggtgaagca agcttgactg caacttatta
     8041 cttaacggtg ccagctgagc tatcacgaat tgattaaaaa ttaagttatt tctcctaaag
     8101 aaaaagttct ctttctaaga tagtggaaag aggacttttt gtgttttggg tatataagct
     8161 tagtttatgg tatttgtaaa attggtgttg gattatgatt taagctagtt ttctaaagaa
     8221 tttgaaaaaa attttattta agcaaaaaaa ccttggttcc aaggcttttc ctgttgtatt
     8281 tagatgcccc ctacaggaat tgtaggagat atgttgttta gatgttcttg attttctggt
     8341 gttttgtaac gtttaaatga gtttttttga gtttgttggt ggggcgttgc ccggcaattg
     8401 cccgacttat tgtttgaaaa agaatttaaa atatggtata gttaattata gattaacact
     8461 tggggggaat agatgaagaa taatgaaaga ttaggtatta aattaagtag agatagcgtt
     8521 ttaggattga gggaagttag aaggctttat ttaggcagtt cagatatccc agttcctgat
     8581 agctatgtga ttgaagttgc ttataaacag atatcaaatg agattgatat tattgattgg
     8641 gtagagttga acaagtcaaa aattaagata agtgaaatta gtgaaagcgt agatatagat
     8701 gccactagct tgagaacaac tttgacttta gacacattag tatatgaagg tatgagagat
     8761 atacagttaa agttgagaga gcttacaaag gggagagtat tcttttcatt tgtagtgaag
     8821 ttagttttat ttgcttctat tttaaagaaa aaaggtttac tagaaaaatt tcaagaaagt
     8881 gttaatcaag tattgacttt ttagttgagt tcaagtatac tttaattaga gagatttctc
     8941 tctaaatttt ttcgcttctt ttgtgttaat caaagatgaa tacaaaaaca tatttttttg
     9001 ctctaaaaag tgttaatcaa tgatgtattt gttagagagg tagataaatg gaattgagag
     9061 caccaccagt tataacagta taaaacgtat aataaaaata ttttaacttg aattatagaa
     9121 aaggagaaac aaatcatgaa acaaaaacaa ccgattgttg ctagaacgaa acaacataca
     9181 tttgaagagc ttattcaaga ccaaaagtta gaaagattag ctaaattttc gcctgatctg
     9241 gttggaaggt atggttttac tgctagctgt gcgtcttcat ttgcgaactt gattaaagaa
     9301 gcgtatgggg gtaaaaatct aaacgtagtt tatgcgagtc ggatgttggc tctctggaat
     9361 attgcttgca gttgttatca taaggctgat gggtattctt tagcagatgc gctttttagt
     9421 gataaaaaaa tttgtctaga ttatttttat tatcataata atacatcaga tatcattact
     9481 cttgatatga tagaggatgt taaaaaaaac tatttacaat tagttactac tgccacttct
     9541 gataatatgt ctgttattga gtttgagatg gaaaaagaat ccgatttgta ttattttatt
     9601 aaagcaacat taggttcttc ttttagtcgt atgcactatt cagtattagt caaggctctt
     9661 gctggtgctc ttgcaaaaaa tatataaata tatattataa tggggagacc ctccccattt
     9721 atatatttaa acaaaggaga aaaaatatgt ttaagaattt ttgtcaaaat gcttttatta
     9781 gcctatattt catagtatca gccctaggag gcttctctgc gcgtctcgag ttccgttcat
     9841 tctcccctta tcaatctatg aaagtagcct tgttattagg agtcatctta attttattgc
     9901 aacttccaat tatgtttgct aaattattag aagctttaaa aatcaagaaa ggtgaaactc
     9961 atgaatgaca tcgtaaaaat gagattagcc ttttgtgttg ctataatatt gatggcatgc
    10021 tctgtttttg tgtttactcc tgttggagaa ggcatgtccc tactttgctc aatttttgct
    10081 accccgtttt tatttatttt tgtcttctat ttttttaaaa taaaattaag aattttactt
    10141 attattatca aggatttcat aaaaaaattt agataggtat aagatgttta aaattaaaca
    10201 aacggcttct ttatctgagc attacttttt aaatacatct aaattgagaa gtattcgctg
    10261 gtttactata ggatttttga gcatattgtc cttttctagt agtattcttt ttaagggatg
    10321 gtttctccaa atgattacat tatctgttga gttaattata attttgtata ttgaaagaaa
    10381 aattaaggga tgggctcagc agattgaacc gctgttaatt gtcagagaaa accttctatt
    10441 tatgcttcgc agaaattcct ttctttttac agcaacaaaa gatggcgcta ttcttcgttc
    10501 agctaaattt aattaccaat tgaatgatgt ttcaattgta gtccatgcat taaaatctgg
    10561 tgatgaattt acgaaagaga tggagacttt agacgttttc ctatctagta ctttgggaat
    10621 aagcctatcg tctaaagaaa tttatgctac tcatgttgaa tatgtttttg tatataaaca
    10681 gcctgaacgt ttatatgtta cctccctccc tcttgaagat gatagcctga aaattaaaat
    10741 ctatgatgat tttgttatcg atttgagaaa aaacttttcc atgcttatat cgggggcctc
    10801 aggtagtgga aaatcattct ttacatatta ttacttgact cgtttcatat cccagaccgt
    10861 aaatgggaaa catgcaaaaa tatatgtgat tgatccaaaa ttttcagata tttataaatt
    10921 atgcgaattt tctggttttc cagtagaaaa ttatggaaca actaatgagg atgcctttag
    10981 aattttgcgt cagtatatca aggagctaga tagacgtatg ctaatctata atcaaagcaa
    11041 tttgttcaac agtattggca tagacttggg ctttcctcct ttacttttgg taatagaaga
    11101 atatagttca ttagttagtt cgatggatag taaagctaaa aaagattttg aaaatatggt
    11161 tgctatcgtt gctcaaaaag caaggtctct atctatgggg gtttgtattg ttatgcaaca
    11221 accccgttcc gatagccttt cgacaaatat tagagaacag cttgtcaatg ctatattcct
    11281 tggagcccca actcgggaat ctagtcagat gatgttcggc acaacagatg tgcccaatgt
    11341 caagaaggat aaaggagttg ggctttgctc tacggataga gagtctccca aggaatttca
    11401 agccccaatt tttaacagag atgtatttga gacaatactc ccagtttggg aatgtgcggc
    11461 taaaaattat atgaaggatg aagatgagaa tgtatgagat agaaatgtaa tgaaggatta
    11521 tgaatctgat accaatccat ataaggcgtt gctaaaagca atgaatatgg ctcacatgtt
    11581 tatcgttgac gagctggaat agagggattg aatattatga ttttaaaaca catctgtggt
    11641 gtgtgagaat cttaagcgtt ttgaagatga ataaaatttt tttattcatt ttcaaaatgc
    11701 cattgtgcag ccggcgaaca acaaggccgg ttcgaacgaa cgttcgaata aatgtattta
    11761 tgtccaatac tgattgacgt taaaagctgt atattatttt aaataaggaa ggatttttta
    11821 actatgaaag aaactgttgt tgttctagct atttctacta agaaagaacg aggctggata
    11881 aaagtctcca cccttaatga ttgttggagt gacctaggta tgcatttcga taaatccaaa
    11941 tttggagctg ttttctctgc tccaggcctt tatgaggttg aagtgattaa taatgcttca
    12001 tttggacaga atgcccaata tgaggtaatt caatccagaa agcttgggac ctttgcagaa
    12061 ttgattgaac aagtcaaaaa ttaaataatt tatatttagg gtaaggctgg acctgccagc
    12121 tttgctggca agtggagcgt ggtcagtgga acggcagtct tgccctaaaa tttaagtata
    12181 tagaatgttt tgttttttga aggagaaatt tcatgaataa agaagtttta aatcgggctc
    12241 cttctaacag cccgataacg atacatcaaa tgtctaataa gagttactct aaatttcaag
    12301 aggaagtatc tctgaagtat gggtttatcg gtctgaaatt ggataagcta agtttgaccg
    12361 ctgaagttag tgaggaattt cattctgaga ttcttagtgg aaactttacc ttatatgatt
    12421 atttcggtgt agttgagccg aatttaaata gaaatggtga actagctagt tataaagggc
    12481 aattctttaa tgatgaaaaa gagaattggt atatcgagta tacccccgtt gcgtcgatta
    12541 agatgaacaa aagaccttta aagattgaat ttactccttc aaaagtttca aaaaagaatt
    12601 ttttaattgt ctttcataga atgtttccgt acatgtttaa catcgcaatc tctacttttc
    12661 atttagctta tgattttgag cgagatttat ctgctttacg tgtaaattgg ccaaaagtaa
    12721 tgtatcgtcc tatttataag gggatgaaac ttgagactat ggattttggt gctcctaaag
    12781 gtaattatca tctaactgct tataataaac ttaaagaacg tatggatagt ggagatatgg
    12841 cagaaataga aatttatcag caatatgata atctatggag gattgagtat aaattctaca
    12901 atgaaggcaa cataaaaaaa gaattaaaaa atggattacc attcttagct aaaattccag
    12961 tgtatattga aaatttcaaa ggcttagaat ttaataattt aggagttaat gagaagattt
    13021 atcttttcgc tcttcgtaat aaacctgaat tatttgcaga atctgataaa cgaacggtag
    13081 ctaagtataa aaaacttgcc gaaagtatct ctgaagttaa tttgaatgtc ttttttcaaa
    13141 atgctttaga ttttgttgaa atctttaatc aagagccttg tctgataaat ttttttgagt
    13201 ttatgaattc tatgttacaa ggcgatattc caaagttaac aataaaccaa gaataataag
    13261 aggggaacag tatgaaagat acgatttcta ataaggattt gatttccatg ggctatagac
    13321 catcaacagc aaatgctatt atccatcagg cgagagaatt acttgtatca cgaggctata
    13381 cattttataa tcgcaaacgt ttgatggttg ttccaaaaag tgttgtgaaa gagttgttgg
    13441 gaatggaatt gtgaaatggc ttatatcgag tatagacagc gaggtaagaa gaagctttgg
    13501 tctttttcta taagagaaag aagcaagagc ctactccata aaagcggatt taaaacaaaa
    13561 cgagaagcta aaatagaagc ggagaaagtt cttcataagt taaatactgg gagtgtctta
    13621 agctctagta tgactttatc ggagctttat aatgaatggc ttgatttaaa aattttacct
    13681 agcaatagaa gtgtagttac taaaaaaaaa tatcttatga gaaagaaggt catcgaaagg
    13741 ttatttggaa ataagcctgt atcacaaatt aagcctagcg agtatcaaaa aattatgaat
    13801 gagtatggag agactgtatc gagaaatttc ttaggaagat tgaattctag tattcaggca
    13861 agtatacaga tggctattgc tgataaggtg ataatagagg attttactgc ttatgttgag
    13921 ttgttctctt ctaagagtgg acaaaaggtt gaggaaaaat atttacatac tgagtcagat
    13981 tatcaaaaag ttttagtata tttgaaaaat aagtttgatt atcagaaatc tattgtaccg
    14041 tatgtaattt atttcctttt taaaactggc atgcgtttct ccgaattgat tgctctaact
    14101 tgggatgaag ttgacgagct taatgagcaa cttaaaactt atcgtcgtta caacaccgct
    14161 attcataagt ttactccacc caaaaacaat acttcaataa gattagttcc tattacttca
    14221 gatatgcttt ccttgttaaa aacattgaaa atattgcaat taaaaacaaa taaagaatta
    14281 aatattgata atgaaaataa tttgattttt cagcattttg gctatgtcta cgatgttcca
    14341 gatattgcaa cagtcaataa agctataaaa gtaatgttga aggaattgca aatttttcca
    14401 ttgattacta ccaaaggagc tagacacact tatggtagtt atttatggca taataatatt
    14461 gatttgggag ttatagcgaa aattttagga cataaagata tctccatgtt gattgacgtt
    14521 tatggtcaca ccttggagga aaaaattagt gaggagttta tggctgtgaa aagtttgttg
    14581 taaaaacacg gcaaattgca cgacaatttt taaaaggaaa gcaaaaaaac cttggttcca
    14641 aggcttttcc tgttgtattt atatgccccc tacagggatc gaacctgtga cccacggatt
    14701 aagagtccgc tgctctgcca gctgagctaa ggaggcaaag aaaaaagctg tattggtgcc
    14761 gaaacttcac ggtttgtatt gaacccgcgc aattaagcag gtgggcaact cgctctaact
    14821 gaagctgttt ccgtgtgaga cggcctacat gctgttagaa gacttttgtt tccctaataa
    14881 tacaaaaaat agtcggtcaa cacttaagtg tgaagtcgta caccacagcg tttctatatt
    14941 tatatgatac cactttttca aaaaaaatca agaggaaagt gcaatttttt gaaaaggatt
    15001 tcagattttt cgcaaatggt cgatagcttc ctttctttga gccaaagccc gttcatattt
    15061 accagtatct tctgcttgga aatagtgatg attacgaatt ttttctggca gatagtcttg
    15121 cttgacccaa tttccaggat agttgtgtgg atagagatag tcttgggcat tccccagttc
    15181 cttgcttcca ctgtagtgcc catcacgcag gtgtcgcgga ataggcaagt gccctgatgt
    15241 tttgaggtca gcaagtgcct tatccatagc tacataggct gagttggatt ttggagaaag
    15301 ggccaaatca atcacgacat tggcaatgag aatgcgggct tctgggaacc caatcttctg
    15361 ggcagcatcc agagcagtca cggtatgaat ctgggcctca ggattggcta aaccgatatc
    15421 ttcataggcg ataacagtca agcgacgagc gagactaggc agatccccag cctcaatcaa
    15481 gcgggcagca tagtggagac tggcatccac atctgagcca cggatagact tttgcagggc
    15541 agatagaaca tcatagtgac cgtctccatc cttgtccata gtgatgtagc ttctctgaag
    15601 actattttcc atgatgtcta aggtgatgtg gcgaatgccc tcgtcattct caggggtaga
    15661 gagaacagcc aagtccagtg agttaaaggc agagcgaagg tctccgtttg tagaggttgc
    15721 gatgaaatcc agcgcatcct catctagttc tattggaaaa ttaaaaccac gttcagggtt
    15781 acttagagct atctgcaggg cctctttgac gtcttggtta gacagaggtt ccaactcaaa
    15841 aatttgaaca cggctacgaa tggcaggagt gacggaaaag aaaggatttt cagtcgttgc
    15901 tccaatcatg atgaccagtc cactttccaa gagaggcaag aggaagtctt gcttggtctt
    15961 atctagtcga tgaatttcgt ctagcaatag gacgagacca ccagaaaatt tagcttcttc
    16021 cgagatttct tgcagtcgct ttttactatc aactgtcgca ttgaaagttc gaaaggcata
    16081 cttggtcgtt ccagcgatgg cagaggcaat actgtttttg ccgattccag gagggccata
    16141 tagaatcatg gaggacaggc ggttggcttc caccatgcgg cggatgattt ttccaggtcc
    16201 gaccagatgc tcctgaccga tgacctggtc gatggtttta gggcgcatgc gaagcgcgag
    16261 attgtctggc atagcagtcc tttctagcgt ggatttgagt agaatgactc atctactata
    16321 tcttactatg tccattctag cctattagtt gtgatatttc aatggttttg taataatcag
    16381 ggagtgagat agaatctttt ttactattta atttaatgag gagaggtatc agcatgagag
    16441 atttgatttt ccttaaagct caaaatagga tagttgagcc taaagaagtg gaagtgctga
    16501 cttgagaaat aatattgctg aatgtcattg tatgaactat aatgaaaaga gaggtgataa
    16561 gcaatggaaa tgatggacca agtcaggaaa ttttgatttt tacaaaacaa attcgtcatt
    16621 ggattcttag tgatcaagtt atttcaggga aaagaaaact tttcttccgg gaagatactc
    16681 caaaagagat tttagatttg tacgaaaaca ttaaatctaa acttgatttt gcttaccaag
    16741 aagttcattc taataatggg ttgaaaaaat atgaaaaata gaataattga tgtttttgaa
    16801 gtagtaaatc gcctccttgt aataactgtt gaaaatcctg atttcgaaga cttgagagtt
    16861 aatcatactc aatgaaaatc aaagagcaaa ctaggaaact agccgcaggc tgtacttgag
    16921 tacggtaagg cgacgttgac gtggtttgaa tttgattttc gaagagtatc agtttgtaaa
    16981 aattggagat aaaaaatata gagtacgcag tggtcctatg attcattcaa ctccgcctca
    17041 atctgtctta gatcgagata cttttacaat tgactataca gatgatgaat tgctcgataa
    17101 agaagcagtt tttactactc attagaaaaa taggtctgaa taaattggtt tcccttagaa
    17161 ccacatctag gggcttttat gtataataga ataataagta tcactccttt acaatacgtg
    17221 taacacgtgt tataatggtg ttgtcaggag gtaaaagcgc tatacctatg acacaaaaag
    17281 agatggttaa actccttacg gcccatggtt ggataaagac tagaggcggt aaaggctccc
    17341 atattaaaat ggagaagcaa ggggaaagac ctatcacaat ccttcatggt gagctgaata
    17401 agtacactga aagagggata ggaaagcaag ctgggttgta aaattcagtc cctgcttttt
    17461 gatatggagg tagtgaaatg ttagttacgt atccagcttt attttattat gacgacacag
    17521 acggaacaga agcgacttat tttgtccatt tcccagattt tgaatactca gctacacaag
    17581 gagaggggat ttctgaggct ttggctatgg ggtcggagtg gctagggata actgttgcag
    17641 atttgataga gagtgatgga gagttacctc agccatcaga tatcaatagc ttgtctttaa
    17701 ttgataatga tccttttaaa gatgatgaag atttcgtgtc aacctatgac cttgataaat
    17761 cttttatttc tatggtatct gttgatgtat cagaatacct aggaagtcag gaacccatta
    17821 aaaagacttt gaccatacca aaatgggcag ataagttggg acgagaaatg ggacttaact
    17881 tttctcagac tttgacagac gctattgcag ataagaaagt tcaagcctaa gattaagcgt
    17941 ggtatcgtgg taatagtcaa taaaaaagca cgtccacttg tgctagttac tcgcctattg
    18001 attttataga tttattagcc ctttcgaggg ctttttatat tgatttttat gagaaatgaa
    18061 gaaatcagac ttttaagaaa atcactgata ccaagggttt aaatgaggta atatggtata
    18121 attaggacat aaaataattt tgtggtaaga tggtagtatc tattttagca tatttccgag
    18181 caatcggggc gattaaagag tcgcatagaa agaggacaaa atggcaacat acggattttt
    18241 agatatttta gaggaagagt tggacaagaa ctttcccttt gactttgaga ttagttggga
    18301 caagcgtaac cacgcggtag aagtgagttt tctattggaa gcgcaaaatg ctgcaggtgt
    18361 ggagatggtg gatgaagacg gagaggtttc atcagatgac attctttttg aggaagcggt
    18421 ccttttctac aatcctgcta agtcaaccgt caatgcagaa gactatttaa cggttatccc
    18481 ttatctacct aaaaaaggat tttctcgcga gtttttagct tattttgccc ttttccttaa
    18541 agatactgct gaggttgggc tagataccct catggacttt ttggaagacc cagaagcaga
    18601 ggaatttgtc atggaatgga accaagaagt ctttgaagaa ggaaaagttg gcttggaaga
    18661 gggagaattt tatccttatc caagatacta ggagttggtt ggaggtgtta tgaagaaaat
    18721 tgggacttat ttggtttatg tgctagctgt tgtctttatt atgctagctt ttgcttgtgg
    18781 aacaatcgca tttgcagagt tggggtattc cgcagtttta gcctttactt ttggttatgc
    18841 cttcgctctt ctaagcatgt atttaatctt tattcttcat gagctgggtc atgctttttg
    18901 tggctacttg acaggctatc ggctggtggc ttttggatta ggacatttta ttttgaccaa
    18961 aaagtcaggc aggtttcatc ttagtagaac agccattctg aaaaatgttg gtgctcaata
    19021 cattggttta aaagaggatg aaagcgatca aagaatcatc ctgatgcttt caggaggctt
    19081 gatggttcat ctcggcttga tattattggc gatagtgttt ggatttttga caagaagctg
    19141 gtattttgca gggacttgga tttttcttaa tttatctttc ttcctaaata acattttgcc
    19201 agtcgacatc accgatggag caaaaatttg ggaattacta caacaccctg aaaataccaa
    19261 atacgcctac ctggtattga gacattctgc tcaaactttg ctggctcctc aagaatatga
    19321 tttgaaagac tttgttcaag cagttcctga ggatgcacga gggagttttg cggatggtgt
    19381 attaggtatg caaggtgaag tttccatttt ggaagggaag gaagaagtag ctaaacagca
    19441 gtttcaagca ttacttgaga ggacaactac tccgatgatg cagacagttg cccaactatc
    19501 cctgcttcat atcgccttgt tggaaggaga ttttgagcaa gcggagcaat atgctagtat
    19561 tcgacaggtc aaatcgtttc tgtctctcaa actgtccaat cttcaagtga tacaagcctg
    19621 gtatcaatta aaggtgaaga aagatgtaga tcgaactcgt aaggctctca agattgctag
    19681 acagaaaatg gatagtagtc gaatgttgag ggacgagaaa cgctattatg aaaacttgtt
    19741 agcagagctg gaaaaggaaa tgttagaagg aactgaagat ggaactagaa atttctgatt
    19801 tccaaggttg caagattgcc ctcttttgtg gggataagct actgacgatt ttgcgtgatg
    19861 acaaggacga tatcccttgt cccaacatgt gggagttgcc aggtggtggc cgtgaagggg
    19921 acgaaagccc ttttgaatgc gctcggcgtg aagtttatga ggaactggga attcatttag
    19981 atgaagactg tctgctttgg agcaagattt atcctagcgt aatttttaaa ggcaagaaat
    20041 cggtctttat ggttggtcag ctaagacaag aacaatttga caatatcatc ttcggagatg
    20101 aaggacaggg ctatcagctg atgaatgttg aggaatttct tagttccagt caagttgtgc
    20161 ctcagttgca agagagatta aaagattatt taaaagtaag tgattagaaa ggatggttca
    20221 gttacatttc taaactgaac ccgccctaaa cactgtgcca aaaagataaa cttctcttag
    20281 acacaagcgt cttcagagaa tttcctattt tggttttgtg ttttacgggc ttggtatctt
    20341 aatgatggaa acatggcaag agttaaaagt tacagtgaag cgtgagggag aggagttggt
    20401 ttccaatctc ttgattgagc tgggagcgca aggtgttgcg attgaagaca gtatggacta
    20461 tgtgggaaat gtggaccgct tcggcgagat tttcccagag gtcgagcagc aagaagaaat
    20521 cgtagtgaca gcctactacc ctgacacggt ggatgtgaca gtggttgagg cggacttgca
    20581 ggctcgcata tcagaattga cggattttat ggatttggga gagttaaaaa taggtacgac
    20641 tgccttggct gaggaagact gggcagataa ctggaagaaa tactatgagc cagctcgtat
    20701 cactcatgat ttgaccatcg ttccctcttg gacagactat gaggcgactg cgggagaaaa
    20761 aattatcaag ctggatcctg gcatggcttt tggtacggga acccacccaa ctaccaagat
    20821 gagcattttt gccttggaac aggttcttcg tggtggcgaa acggtgctag atgtgggaac
    20881 tggttcaggg gttctctcta ttgccagctc gcttctgggg gctaaagaaa ttttcgccta
    20941 tgacctggat gatgtggcag ttcgtgtggc tcaggaaaat attgagctca accctggaat
    21001 ggaaaatatc catgtagcgg caggcgattt gcttaaaggc gtggagattg aagcagatgt
    21061 catcgtggca aacatcttgg cggatatcct cattcatctg acagaggatg cttatcgctt
    21121 ggttaaggat gaaggttacc tgatcatgag tggcattatc aaggataagt gggacatggt
    21181 gcgcgagttg gctgaatcag ctggattttt cctcgaaact cacatggttc aaggggaatg
    21241 gaatgcctgt gtctttaaga aaaccaagga tatctctggt gtgattggag gctagcatgc
    21301 agcagtattt tgtaaaaggc agtgctatct ctcctgtcac tatcgagaac aaggaaacca
    21361 gtaagcatat gtttcaggtt atgcgcttga aagaagagga tgaggttacc ttagtctttg
    21421 atgatggcat caagcgcttg gcgcgcgtgc tggatatgga aaatcgtcag tttgagttgg
    21481 tccaagaatt aaatgacaat gtggaactac cagttcaagt gaccatcgca tctggatttc
    21541 ccaagggaga caagctggag ttcatcgctc aaaaagtaac cgaactgggt gctagccaaa
    21601 tctgggcctt tcctgcagac tggtcagttg ccaagtggga tggcaagaaa ttgggtaaaa
    21661 aagttgaaaa actagaaaaa attgcccttg gagcagccga gcaaagcaag cgtaatattg
    21721 taccaagtat taaacttttc gagaaaaaag cagattttct aactcagctg gaccagtttg
    21781 actctatcat agtagcctat gaagaatcag gtaaagaagg agaagccgct gcgcttctgc
    21841 aagcagtcac tggtcttgaa acaggagcca aactgctctt tatctttggt ccagaaggcg
    21901 gtctctcacc tgcagaaatc gaaagttttg aagctaaggg agccgttttg gtaggcctag
    21961 gtcctcgtat tttgcgagca gaaacagcac cgctttacgc cttatcagcc cttagtgttt
    22021 tagtagaatt agagaaataa gaggaagaaa atggaacaaa aacaccgttc agaatttcca
    22081 gagaaggaac tctgggactt aacagcccta taccaagacc gtgaggattt cttgcgtgca
    22141 atcgagaaag ctcgtgaaga catcaaccaa tttagccgtg actacaaggg taatcttcat
    22201 acttttgagg atttcgagaa ggcctttgcg gaattggaac agatctacat tcagatgagc
    22261 catattggca actatgcttt tatgcctcag acgacggact atagcaatga cgaatttgcc
    22321 aatattgccc aagctgggat ggaatttgaa acagatgcca gcgtagcctt gaccttcttt
    22381 gacgatgcct tggtggtagc agacgaggaa gtcttggacc gtttgggtga attgcctcac
    22441 ttgacggcag ctattcgtca ggccaaaatc aaaaaagccc actatctagg ggctgatgtg
    22501 gagaaggcct tgaccaatct cggtgaagtt ttctatagtc cgcaggacat ttatactaag
    22561 atgcgagctg gggattttga aatggctgac tttgaagccc atggcaagac ctataaaaac
    22621 agctttgtca cctatgagaa tttctaccaa aatcacgagg atgctgaggt tcgtgagaaa
    22681 tccttccgtt ccttctcaga gggacttcgt aagcaccaaa atacggctgc agcagcctat
    22741 ctggctcagg tcaagtctga aaaactcttg gctgatatga agggatacga ctctgtcttt
    22801 gactatcttc tagctgaaca agaagtggac cgtgtcatgt ttgaccgcca gattgacctc
    22861 atcatgaagg actttgcacc agtcgctcag agatacctca agcatgttgc caaggtaaat
    22921 ggtcttgaaa agatgacctt tgcagactgg aaattggact tggacagcgc cctgaatcct
    22981 gaagtgacta ttgacgatgc ctatgatttg gtcatgaagt cggtagaacc tttggggcaa
    23041 gaatattgtc aggaagttgc tcgttaccaa gaagagcgct gggtggactt tgctgctaac
    23101 agtggcaagg attccggtgg ttatgcggcg gacccatatc gcgtacaccc ttatgtcctc
    23161 atgagctgga caggccgttt gagcgatgtc tataccttga ttcatgaaat cgggcattct
    23221 ggtcaattca tcttttcaga caatcatcaa agttacttca atgcccatat gtcgacctac
    23281 tatgttgaag caccgtcaac cttcaatgaa ttgctactca gtgattactt agagaaccaa
    23341 tctaatgacc cacgtcaaaa acgctttgct ctggctcatc gcttgacaga cacctacttc
    23401 cataacttta tcacccacct cttggaagcc gccttccagc gtaaggtgta tacattgatt
    23461 gaagaaggag aaaccttcgg agcaagcaaa ctcaacagca ttatgaagga agttttgaca
    23521 gatttttggg gcgatgccat tgaaatcgac gacgatgcag ctttgacttg gatgcgccaa
    23581 gctcactact atatgggctt gtatagttac acttactctg ctggtcttgt catctcgaca
    23641 gctggttacc ttcatcttaa aaactcagaa actggagctg aagactggct caatctcctc
    23701 aaatcaggtg gtagcaagac accacttgag tcagccatga ttatcggtgc tgatatttca
    23761 acagacaaac cactccgtga taccatccaa ttcttgtctg acacagttga ccagattatc
    23821 gcctacagtg ctgagttggg ggagtaaggg gaatagaaaa attttttaga atgatgttta
    23881 tgggcttgtt aagcgtcatt ctatttgtct tagttgtagc tattttcaaa aatgtcgttg
    23941 aaggtcgtga tgttaaattt gaacttactg tagaactggt attgatagtt atttacgtca
    24001 ttttatatca gattgtattt aattgagaat tcaatattga gtcatttaag actgcctttt
    24061 tgaacagttg ctagaaatgt agaggtattg accatgtatc aagatttact aagaaaaata
    24121 gcagaagaaa aaccaaatta taaccaggag gaaatccagt ggttgcttga tcatttggga
    24181 gatccttctc cagaaattcg cgatgacctt gtttttacaa gctttgctag agggattcag
    24241 gaagagctat ttacacagga gcaatttcat ttcattgctg aaggggtttc atctgatgta
    24301 ggactagata aagagattga taaggtaggt ctgccaacac ttgaacgttc ttttagggca
    24361 cttgtttatg caaatctctt gtatgcagat gccaaccagc aatcggtttt ttatcaggga
    24421 ttacaattag aaattcgtaa tgtcttttca aatcaaggct tgcactatct ttcaaaagaa
    24481 aaggatacaa caggtttctc aagtcagtat ggttgggttc atgcttttgc acatggagcc
    24541 gatttactga cagaggtggt ctgtcatcca gactttccta taaacagaat tcatgaagta
    24601 tttgacatac ttggccaact atttaaaaga atgtcgattc gctttacaga tgatgaggat
    24661 tggcgtttag caagagtgat ctatgaacct attttacaag ggaagttgga gcaagaacaa
    24721 gtagcttctt ggataaaaac tgttgatttt ccgatagaag aaagggagga tttttccaaa
    24781 ttttccaact ttagatcctg tctggtggaa gtctatgtcc aacttgacca gagaaatagt
    24841 ttacaagatg agttgaaaga agctatccag tcttttcaat actagagatt agctaatagt
    24901 tctatgattt tcaaaaaatt tccaatcaat tttcttgaaa ccctttccta cttttgatag
    24961 actagtatct agtttttgaa aaaaggagaa agaaaatgaa aaaatttgtt gctgagttaa
    25021 tcggtacgtt catgcttgtg ttcgttggga caggagctgt tgtttttgga aatggttttg
    25081 atggccttgg tcaccttgga atcgcctttg cctttggttt ggcaatcgtg gtggcagcct
    25141 actcaatcgg aactgtttca ggtgctcact tgaacccggc tgtttcgatt gctatgtttg
    25201 taaacaaacg tttgtcatct tcagaacttg taaactacat ccttggtcag gttgttggag
    25261 ctttcatcgc ttctggcgct gtcttcttcc tcttggctaa ctcaggtatg tcaactgcta
    25321 gtcttggtga aaatgccttg gcaaacggtg tcactgtctt tggtggtttc ttgtttgaag
    25381 tcatcgcaac tttcttgttt gtattggtta tcatgactgt gacttcagaa agcaagggca
    25441 atggcccgat tgctggtttg gtaatcggtt tgtcattgat ggcgatgatt cttgtcggat
    25501 tgaagattac tggactttca gtaaacccag ctcgtagctt ggcaccagct gtcttggtag
    25561 gcggcgcagc ccttcaacaa gtttggattt tcatccttgc accaatcgct ggtggagttc
    25621 ttgcagccct tgttgcaaaa aatttccttg gaacagaaga ataattgaaa ctcaaaaagc
    25681 cttgctcctc atcttgagga acagggcttt ttcgtatgat actcttcgaa aatctcttca
    25741 aaccacgtca gcttcacctt gtcgtaggta tggttactga cttcgtcagt tctatctgca
    25801 acctcaaaac agtgttttaa gctgacttcg tcagttctat ctgcaacctc aaaacagtgt
    25861 tttgagtaac ctgcggctaa cttcctagtt tgctctttga ttttcattga gtatgacttt
    25921 agcggttgtc aattttctct ggataaaggt cgtgttggaa gaggcgttgt tctgccaagc
    25981 cctcatactt agttccttgc ttaccgtagt tgtagtaggg gttgattgaa atgccaccgc
    26041 gcggagtgaa tttcccccag acttctaaat agcgagggtc tagcaagttg accaagtctt
    26101 tcccgatggt gttgatacag ttttcgtgga aatctccgtg gtttcggtag ctaaatagat
    26161 atagtttgag ggattttgac tcgacacaga gtttgtcagg aatgtaggaa atatgaatcg
    26221 tcgcaaagtc tggctgagca gtgatttgtc ccagcagaga catatcgagg atatggtgac
    26281 gaatgccctg ttccttagcg atttctctat taatttgaat ttcgaggtga tgacgttggc
    26341 cgtaggcaaa ggtgacagct tcgactgttt catagtactc cttccaaaat gggaaatgtt
    26401 cagagcatgc aaaaagctcc cattagggag ctaaaaaata ccaaatcgag tttttttagc
    26461 gatggcatat cccaaacatc gtaatattct acttatatag taaaatgaaa taa
//
LOCUS       DAVAGB010000026        25626 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVAGB010000026 DAVAGB010000000
VERSION     DAVAGB010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25626
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.026"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(207..977)
                     /locus_tag="VQO19_001255"
     CDS             complement(207..977)
                     /locus_tag="VQO19_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HET1349525.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(992..1840)
                     /locus_tag="VQO19_001256"
     CDS             complement(992..1840)
                     /locus_tag="VQO19_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HET1349526.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYSHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(1837..3312)
                     /locus_tag="VQO19_001257"
     CDS             complement(1837..3312)
                     /locus_tag="VQO19_001257"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HET1349527.1"
                     /translation="MVQTKQPNIILIVVDQMRADVLSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTKF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(3635..4990)
                     /locus_tag="VQO19_001258"
     CDS             complement(3635..4990)
                     /locus_tag="VQO19_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET1349528.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLDPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(5000..5317)
                     /locus_tag="VQO19_001259"
     CDS             complement(5000..5317)
                     /locus_tag="VQO19_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET1349529.1"
                     /translation="MNESNLESAMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTKEAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(5334..5651)
                     /locus_tag="VQO19_001260"
     CDS             complement(5334..5651)
                     /locus_tag="VQO19_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET1349530.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(5666..6562)
                     /locus_tag="VQO19_001261"
     CDS             complement(5666..6562)
                     /locus_tag="VQO19_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HET1349531.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLKRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(6559..7827)
                     /locus_tag="VQO19_001262"
     CDS             complement(6559..7827)
                     /locus_tag="VQO19_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET1349532.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLEDCE"
     gene            8107..9285
                     /locus_tag="VQO19_001263"
     CDS             8107..9285
                     /locus_tag="VQO19_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET1349533.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDNYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(9513..9959)
                     /locus_tag="VQO19_001264"
     CDS             complement(9513..9959)
                     /locus_tag="VQO19_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET1349534.1"
                     /translation="MTIRFEEKVSIENAQLVCQWSNSLGKVFQEQWMGPRIPFPLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQGQGLDSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRVQNLYQKEGFEIVQMVEAPVRKYSRLKLE"
     gene            10029..10688
                     /locus_tag="VQO19_001265"
     CDS             10029..10688
                     /locus_tag="VQO19_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HET1349535.1"
                     /translation="MIDIYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLH
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLFYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(10660..11436)
                     /locus_tag="VQO19_001266"
     CDS             complement(10660..11436)
                     /locus_tag="VQO19_001266"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HET1349536.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFIYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(11429..12652)
                     /gene="trpB"
                     /locus_tag="VQO19_001267"
     CDS             complement(11429..12652)
                     /gene="trpB"
                     /locus_tag="VQO19_001267"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HET1349537.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDMTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(12630..13229)
                     /locus_tag="VQO19_001268"
     CDS             complement(12630..13229)
                     /locus_tag="VQO19_001268"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HET1349538.1"
                     /translation="MTKVKICGLSTEEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPSDVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(13216..13983)
                     /gene="trpC"
                     /locus_tag="VQO19_001269"
     CDS             complement(13216..13983)
                     /gene="trpC"
                     /locus_tag="VQO19_001269"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HET1349539.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALAEERLKELYDYATVLGLEVLV
                     ETHNLAELEVAHRLGAQIIGVNNRNLTTFEVDLQTSVDLAKHFKDDCLYISESAIFTR
                     QDAERLAPYFNGILVGTALMQAENVVQRIKELQIDKG"
     gene            complement(13980..14984)
                     /gene="trpD"
                     /locus_tag="VQO19_001270"
     CDS             complement(13980..14984)
                     /gene="trpD"
                     /locus_tag="VQO19_001270"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HET1349540.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(14995..15561)
                     /locus_tag="VQO19_001271"
     CDS             complement(14995..15561)
                     /locus_tag="VQO19_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HET1349541.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(15558..16919)
                     /gene="trpE"
                     /locus_tag="VQO19_001272"
     CDS             complement(15558..16919)
                     /gene="trpE"
                     /locus_tag="VQO19_001272"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HET1349542.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYIVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEVMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(18060..19061)
                     /locus_tag="VQO19_001273"
     CDS             complement(18060..19061)
                     /locus_tag="VQO19_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET1349543.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            complement(19346..19537)
                     /locus_tag="VQO19_001274"
     CDS             complement(19346..19537)
                     /locus_tag="VQO19_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349544.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKC"
     gene            complement(19633..20343)
                     /locus_tag="VQO19_001275"
     CDS             complement(19633..20343)
                     /locus_tag="VQO19_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HET1349545.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            complement(20346..22037)
                     /locus_tag="VQO19_001276"
     CDS             complement(20346..22037)
                     /locus_tag="VQO19_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET1349546.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            complement(22049..23059)
                     /locus_tag="VQO19_001277"
     CDS             complement(22049..23059)
                     /locus_tag="VQO19_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1349547.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELFGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            complement(23162..24229)
                     /locus_tag="VQO19_001278"
     CDS             complement(23162..24229)
                     /locus_tag="VQO19_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET1349548.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGSLIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVQ"
     gene            complement(24254..24913)
                     /locus_tag="VQO19_001279"
     CDS             complement(24254..24913)
                     /locus_tag="VQO19_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HET1349549.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            complement(25093..25409)
                     /locus_tag="VQO19_001280"
                     /pseudo
     CDS             complement(25093..25409)
                     /locus_tag="VQO19_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
BASE COUNT         8122 a         5532 c         4005 g         7967 t
ORIGIN      
        1 ttttccaaca cctgatatta tgcatttttt aattttaaag actttttccc agcctcaaga
       61 aatcacatcc cacctaaatc ctttggatac caaatacctc atcaggtatt ttctgagttg
      121 gtaagactgt ctagcttaat ttgacaaatg gagggcgtta aatccagttt ttacaggaag
      181 tctatttaaa tattttcaca ctgaccttac aaaatatgaa ataaattata taaagtcatt
      241 cccatgacaa agaataacat ccctttaaaa cagtatctta cccaattttc aggtaagact
      301 tttgatacaa ccgtccccaa tacccctccg catatagaag caagaaaaat aactggaaca
      361 ggtgctaaat gatactgatt taaacctgta accacaacaa ttgtagccaa atgagacagc
      421 tgggaaaaga aaataattgc aagagaatac atcgttgctt cttttatcga aatagaaaaa
      481 aacaccatca ataaagatac attgagcgga ccaccaccaa tccctaaaaa actagaaatt
      541 aagcccaata gaagaccaca aatcatatag aatcctatct tatcaaattg ataagttttt
      601 ttaaaatctg ttaaaacaaa tgatacaagt agcatcacaa atagtaaaat catttgaaca
      661 atggatacta gccgtactga taactgagat aacaaaactt gaaaaataag atgacctaga
      721 aatcctccta aaacagaaga aaaggatacc gtaaaaatca atctccattt tatctcttta
      781 ctttgtgaaa atcttttgat tgttgaaata atcgccatta taaaaacaga gaaactagaa
      841 taaaaagcaa tatcactgac cgaatggtat ccaaaactat ccataagtgg cttaattata
      901 attccaccac ccatgcctga tatagaaccc aatccactag ctattataat gattagaaaa
      961 taaataatct caaccacttt ttaagtccat cctattcttt caaacatcta aaacctagat
     1021 ggctactagt ggaagtagaa atacatccat ttctagcagc tactcggtat cgattacaat
     1081 aagaacaatg acataaaaag gaacctcctc tgatagcata ctcctcatct tgtatcccat
     1141 attttggtaa ctcatagtca tcttcattaa aactagctaa taaggtatat ctcggattgc
     1201 gacaccattc ccaaacattc ccaatcattt gatatagacc aaaatcatta ggtaaaaatt
     1261 catagacagg agccgttcct ataaatccat ctaaggcagt attttcataa ggaaatcttc
     1321 cttgccaagt attggcatga taatatccac cttctaaaag agtatctccc caaggatatt
     1381 cagattgtct tcctcctcta gcagcatatt cccactgtgc ttcagtcggt aaagacattc
     1441 cgctccaatt acagaaagcc aatgcatctt ctaaagcaac atgaactact ggatggtctt
     1501 ctaaacccac tagattacta ttctcaccgt agggatgttt ccagcaagcg ttcggaactt
     1561 gtaaccacca cggagcccca gcaggatgag aatatccctc cctttctgcc tctggaacga
     1621 acaatataaa aacaaaagac cactcttgtc gctcagctag tgttttatag cctgtttctt
     1681 tcacaaattg agcaaattct tgattcgtaa ctggagtatc cgcaatggaa aaatccttta
     1741 cactaacagc gacttgagga ccttcaaaat catctaaaaa gccctcttca gaatttgttc
     1801 ccatcataaa tgtcccaccc ttgatttttt tcattttcat gattgactat cccccgtttt
     1861 cgttagagtt ggcgttattt tagaaagttc aacaggaact aactcttcat ccacaacaaa
     1921 accttcttct ctatatctaa gaaagtctac taattttttc ttcatctgac gaacaatagg
     1981 ttggtatttt tcacttggat acaaatcatt catttcatgc ggatcttttt tcatatcaaa
     2041 taactgataa tgatttaaaa caggaaacca gataaatttc cactggtctg tcaagatata
     2101 ttgactagaa tcttttccta aagcatgttc accatgaaat tttgttcgcc acccctcgta
     2161 ctgtccaaat aataaattct taacactccg tccatctagt tcatctgtag tagttcctcc
     2221 tgccaaatcc acgagtgaag gaaaaatatc ttgaattttc actaattgct tgattgttcc
     2281 cctattacca gctatcaatc cagccggatc gtaaataaac gaaggaatgt ggatacttcc
     2341 ctgataagga tatccctttc taaacagata atgttcacca agctgatctc catgatccga
     2401 aacaaaccag ataatcgtat ctttatcatg acgaaattct tttagggcag tcaaaaagcg
     2461 actaatttga tggtctatat gagtaatcaa tccaaaataa gcagcaacca ttcttctttg
     2521 atcatcttcc tttaatttcc ctcttaaagc ataaatagac ggaatttgct tttctaatac
     2581 ttcccaattc ccgatatgca aatcgagaaa ttgaggcaag cgttccatat acatatcaaa
     2641 atagtatttt gggggattta atggagcatg tggtttttca aaagacattt tgagaaaaaa
     2701 aggaaccgtt ggatctcttc tttgtaaaaa tgaaatggac tcactcacaa cccagtttgt
     2761 tggatgtaac ttctcatctt tatcccaagg tctagcttcc caagaattac aatccattcc
     2821 gtcatcaatc aaatcaacat cataaccaac tttacccttt aaaaaggcta gatagtcact
     2881 agcataatca aattgacttc cataagcctt atcatacttt ctatcaacat gtagataccc
     2941 atcgtgaagt aagacatgat caaacccaag tctctgtctg gaaggaaaaa catgcatctt
     3001 accaatacac tctgtttgat aacccatatc tttaaagact tttggaagag tattagtaaa
     3061 attccaaggc acctcatctt gataaccaac tcgtccactt ttatcttggt ctaagccagt
     3121 caataaagct gccctagcag gaacacaaga aggaactgga gaataggcat tttcaaaatt
     3181 ataacctaca ctagccatca tatctaatgt tggagtgcta actagcttat ccttactatt
     3241 caaggataag acgtctgctc tcatttgatc tacaacaatc aaaataatat ttggctgttt
     3301 tgtctgaacc ataaaatctc ctttctaata tggcaaaaga ggcacaagaa gatatctacc
     3361 tttactgcac ccctttctat atcaatctct ctatataaaa caataacatt cttgttatgt
     3421 tttatagaaa aatgaactaa aatatgacta aatcgattag gaaattcaaa tcattttcta
     3481 gtactgtttt agaagttaca gtgtactatt ccaacttcaa taaattataa acctttgtct
     3541 aataacaatt ttagtggaga taagaaatcc tacacctaac tcatcttaca cgtaatctat
     3601 ttctatttta tcacaaaaaa cgcaagtaag accattaact caattcagtt ttatctgcca
     3661 ttttcacaaa tgggaaataa gtcaagacac taataatcaa acaaacaact gataagatga
     3721 tggcacgcca atcaaatgct gtagagaaga aaccatataa aattggaggc attacccaag
     3781 taacgttttg tgtaacaggt gaaacaagac cccagcttgt tgcccagtaa gctaccgttg
     3841 ccatgaaaac cgggctaagt acaaatggta taaatagcaa aggattcaag acaactggta
     3901 aaccataatt gaccggctca ccaatattaa acagaactgg tgctagacca agtttagcaa
     3961 cttttcgata atgactgttt cttgaaaaaa ttaaaatagc aagtactaat cctaatcctc
     4021 caaaccagac aaacgcccca aaagacccac ttgtccatat ataaggaatc ggttcacctt
     4081 tttggaaagc atccagattc gctaacatag caactccaaa cagcccttcc atgatgggat
     4141 ccaatacatt tcctccatgg agaccaaaaa accagaataa cttattcaaa aagatcatca
     4201 gaataactgc aaagaaactt tgagacaaac ctagtaatgg cgtttgtaac accttgtaaa
     4261 cccaatcaat caataagtca ttgctaagta aatggaaaac ataagtcaag atggctacta
     4321 tatacatcgc cataaatcct ggaatgatag aagtgaacgg cttagcaatc gcagggggaa
     4381 ctgaatctgg taacttgatt acccagttct ttttcattac tttacagaaa ataatagagg
     4441 ctaaaaatcc aatcatcatg gctgtaaagt agcctctggc attaatatgg tttcctggaa
     4501 tcacattccc aatagttacc atcagatttt taccatcaaa tgctagatta tcaattcctt
     4561 gtaagatttg atctaatttc acatctccta catttgccaa agggaaactc tttgtaactg
     4621 tacttccaat cgaaatgaca aacgaagcaa gcgataccaa accagcagaa actgtatcaa
     4681 ccttataaat cttagcgata ttcactccca agcaatagat gaacaataag gaaacaattg
     4741 gtatacttcc cttgaatacc aaattattga tgtcaacaag ccactgaaag gttttcgtaa
     4801 tactttctag gtgaaattgt tgtggtaaat ccactagaaa agcatttaat aacaaagcaa
     4861 tggaacctgt cataataaca ggcatagtcc ccacaaatga atcacgtaaa gcaactaaaa
     4921 acttctgatt cccaactttc attgcaattg gagaaagttt ttcttgcatt ttatccaaca
     4981 ttgtattcat agcaaattcc taattttttt caaatcgttc gtatacttct accacttctt
     5041 tcgccaagtc aacaaaggtc agactcgtca ttaaatgatc ttgcgcgtgt accatcaaga
     5101 ggctaattga tgtttcttcc ccctgtgcct cttttgtcaa catttctgtt tgagccttat
     5161 gcgcctgtaa taaggcagca ttcgcatcag ctaatcttcg attggcttta gagaaatccc
     5221 ctttttttgc tgcctgaata gcctccatag cattactttt ggcttcccca ccatacataa
     5281 ttagccccat tgcagattct aaattacttt cattcatagc attctcctca atcttagtct
     5341 aataaacttt cagctaaatc taagacttta gaaccattca tcattccata atctgtcatc
     5401 ggaataaccg ccacaggaat ctgtctatct tttagttttt cttgaaagtc ccctagtaaa
     5461 tagcgaactt gagggcctaa aagcaacaca tttacttctt ttgttgctac aatttcttct
     5521 gcttcaggag ctggaactgc aaaaatttct gcatccaacc ccttatcttc tgctgccttt
     5581 tgcatctttg tcactagcag acttgtactc atacctgctg cacatgctaa cataattgtt
     5641 actttagcca tagcttactc ctttatcacc tatttactga cctagccaag cgagatactg
     5701 tatgtctcac tcctctaatt gccttgctca atgcataaat attatcgact gttgccagtc
     5761 ccccatatcc tgcgtcacct atatgttgaa tatcaactcc acaaatttta tttctaagtg
     5821 caatttcctt aatagtatct gtatcagatg tttcttggct agtaccaata gcactcaata
     5881 caagaccacc cttactatga acgagatcaa cgacttcacg caactcttgg tcatgaaagg
     5941 ctggaacggt tccaactgct ggaacaagta tcacatccgc acctgcttcc aacaattgct
     6001 ctgcgacaga aagctctgcc acaggctcat tcactcctgc cccgtgcatc ttacctgcaa
     6061 taatcaaacc agaaaagttt tccttagcag tttgaacagc cttaatgatt tctcgattgc
     6121 taactcctgt tccaggattt ccagtcaaac agacaaagtc aaaacctaac tcctctattc
     6181 gcttcaatgt ttcaacacta gcaacacgac ctgcaacaat ttcctgtgtt tcctctagca
     6241 tctttgcaga tgggtcaatc ggttccaaat ttacaccaat tggacaagca acaagctggt
     6301 gtaagcgatg aataacatca tcacctgaac tatccaaagc ataaatttta ggctcaaaaa
     6361 catcaacaca attcaataaa atcatatcag ctccaaaagc tctagcaatt tcagaattag
     6421 ttatatcccc aacaaatgtc tcacgagtaa ctacattttc agatagaaca actctacctt
     6481 cacttgctaa aatactttgt tttaattctt cagcattcat ctgtaatatc tcagatggat
     6541 ttgcactaat taaacgtttc attcgcaatc ctccaataac ttaaaccgtt tttcaatagc
     6601 tattacaaat ggtaaataaa gtaagacatc caaaacaatc aatacaattt gtaataatga
     6661 accagaaata cttcctgtag caagtaaacc acttataaca ggtggcatag tccaacctgg
     6721 atctgtataa gttagcggaa ccaaacctga tgccattgct ccccacgcta ctagtaagtt
     6781 aaacattgga gctaagataa atggaactag taacaaaatg ttcaaaacaa taggaacgcc
     6841 aaacattgct ggttcattta tattaaataa tccaggtata acagttatag gtgccaaagt
     6901 ttttagttgt ttactagctt tcttcttatg tgctaaatat cctaacgcaa gaactaaacc
     6961 tatggttgca ccaccgccac ctatgaatac aaaattatcc ataaatacgc tagtaaaaat
     7021 atttggaaga gtttctccag tttgataagc tactttattt gcatctagat tagctaacca
     7081 taacggtttc ataactgcat taacaacatt tcctccgtgt aatcctacaa accaaaaact
     7141 actattaagg aaaattaaga taagaaggcc aataacatta tttcctaaaa gtccaagtgg
     7201 acctcccaaa gctacttgag caatttcatg aagattaggt aaacttaatt tatctaaagt
     7261 tgcataaaca atcaaccaac caacaatagt cactgcacca ggaataatgg cactaaagct
     7321 tttagatact gctggtggaa caccatccgg catttttatc tgtatattat gatttataaa
     7381 ccattggtag atatagccat taatcaatcc taaaatcata gcaacaaata aaccttttga
     7441 tgccatgaaa gcggtaggca ttcctgctcc agcctctcct ctaatgaaag gcgtaactgt
     7501 aataaaagat gataatgaca caataccagc aggaatacca tcaactttgt attgtctagc
     7561 cataaagtaa gcgataccaa aactagctac aagaccaagt aatccaaaac tactatcaac
     7621 acccttccat aaatagtcag caacaccaat atcacccaga tatttttccc atcctggaat
     7681 aggaaaactt gcaataacca ttagtaatga acctatcaac aataaaggta tagttagagt
     7741 aataccgtct cgaatagaaa ccaacgcttt attattaccc aatctagccg ctactggaag
     7801 taacttttct tgtaataatt tttccataac cttttcctct taaatatatt ttattatcaa
     7861 aagttatcaa ttatctttat tttttgacgt caagttgtta tttgattatc ttttgttatt
     7921 tatattttac aactataaga aagccttgtc aaggatttgt gtaaacattt gattattttt
     7981 tattatcaat atataataaa aagagaccag taagtaatga aaagcttaaa aagattaaca
     8041 tctacattta tccatagcaa aaaatcatag gattttaaga atctgacaac taggaagaaa
     8101 actaatatga ccttatctaa gaaacaatta caactaagag ctaaaatact ggaaacagtt
     8161 tacacattag gtcccatttc acgaattgaa atcgctacta aaacaggaat aacacctgca
     8221 acaactagca gtatcacaaa tgatctgatt aaagaaaata ttctcttaga acttggtgaa
     8281 gacgaacacg atacaagcgt agggagaaaa aaaatcctgc tagacattca agctaaacga
     8341 ttttactaca ttggttgtga actatctgaa aaacatttca cttttgcttt aggagataat
     8401 ctaggaaata tcttaaagga agagaaagaa attgttacta aacagttaat ccaagaaaag
     8461 ggaaatcaac tcattaacca gacactaaag caattcttaa ataactgctc tgattatgaa
     8521 atagaagcaa ttggaatcgc gctacctggt cgctatttag ataattataa aataacaaca
     8581 aacaatcctt tatggcaaca tatcgactta gaaatgattc aatcccactt tgataagcct
     8641 ttgtttttct ctaacaatgt taactgtatg gctataggta aacgcctatt tagtcgccaa
     8701 cagaatgacc ctaattttgc ttattttcat tttgctagag gtatgcactg ttcttatatc
     8761 tacgacggaa acatttatgg gaaaggaaat ctaatgattg gagaaatagg gcatacagtt
     8821 gtttcatctg agggagaaga atgtagctgc ggacgcaagg gatgcttaca aacttttgct
     8881 ggagaatctt ggttaatcaa aaaatcaaaa attctatatc atcaatctcc ctattctcta
     8941 cttcctagtt tagtcaaaaa tgccgatgat attgatatcc aagttatttt aaccgcttat
     9001 caattaggtg acactggaat aatcacactt atccatcaag ccttactcta tcttagtcaa
     9061 accattttaa atatcagtat gatgattgac tctcaaaaaa tctacctaca tagtccttta
     9121 ctaacaaatc aacacatcat ccaaaaacta tatagtgaaa tgaactacaa acccaaactg
     9181 ctctataatc gcctacctga agtcattatt gaaccttaca atgattttac agccgcacac
     9241 tcagctattg cactttgttt gtatcataca attctacatt cttaattttc tattacattt
     9301 aataaatagg ctaaaaagag ggagtatatc ataaaaagcg aataaacctg ttttctgaaa
     9361 atcagaattc tgttttgttc gctttcttta tatttggaat tatactccta tctccccttt
     9421 ttcataatgt ataataaaat gaaataataa caggacgaat cgatcgggac agtcaaatcg
     9481 atttctaaca atgttttaga agtagaggtg tactattcta gtttcaatct actatatttt
     9541 cgtacaggtg cttcaaccat ttgaacgatt tcaaatcctt ctttttggta aagattctga
     9601 actctttgat ttgcctcgaa gacatttaga gaaatactat ctatatcttc attttcaaag
     9661 gccaaactaa caaatttcct taaagcttgg ctatctaagc cttgcccctg tttctggggg
     9721 ttgataaaaa atctcccgat atgaagattg ctgtcttcta gcctgatttt ctggataagt
     9781 cccacaaact cttgttcatc aaagattgaa aagactcctt ccaaggcttg aagggtcagt
     9841 ggaaaaggaa tccttggtcc catccattgt tcttgaaaga ctttgcctaa ggagttggac
     9901 cactggcata cgagctgagc gttttctata ctcacctttt cttcaaaacg aattgtcatc
     9961 ttttcctccc catcttatct atgtttctcc attatactac ttctcccatt ttttacgaat
    10021 agataagtat gattgatatt tatttttttc ttgtcgggag cattctcgct tcctttcttg
    10081 gtttggtcat tgaccgtttt ccagagcaat ccattatcag ttcagccagt cactgcgatt
    10141 cctgtcagac tcgcttgcat cccttagatt tgattccgat tctctcacag gtcttcaatc
    10201 gctttcgctg tcgctactgc aaagttcgct atcctgtctg gtatgccctc tttgaactag
    10261 gcttaggact cctctttctg ttttactctt gggaattgct ttccttgggg caagtcgtcc
    10321 taatcaccgc tggtttgacc ttgggtatct acgactttca ccatcaggaa tatcccttac
    10381 tggtctggat gactttccac ctaatcctaa tagcttcctc tggctggaat ctggtcatgg
    10441 tctccttcct catacttgga attttggctc attttatcga tatccgcatg ggtgcagggg
    10501 atttcctttt tttagcttct tgtgctctcg tctttagcgt aacggagtta ctgatcttga
    10561 ttcagttcgc ttctgcgacg ggtatcctgg cctttctcct gcaaaagaaa aaggaaagac
    10621 ttcctttcgt gcctttcctc ttacttgcta cttgtttgat tatttttggt aagctactgc
    10681 ttgtttgata aagtcctgaa tcggctctcc ttggtggaga gcttttacta ttttcgaacc
    10741 gacgataaca ccatctgaca ccgcattgaa gcgttccaga tcggcttgac tagatacacc
    10801 aaaacctgtc aagactggga tgtcggccac ttgatgaagt tgcgccaagt gcttgtccaa
    10861 atctgcacgg taattgcctg atttccctgt cactccattg atggcaacgg catagatgaa
    10921 tccctccgcc ccttcaatca actctttctg gcgctcaatt cctgtggtca agcttactaa
    10981 aggaatcaag gcgatatctg tatctgccaa aaatggttct acaaagttgg catgttcatg
    11041 aggcaagtct gggataatca agcccttcac agctgtatca gccagatctt tgacaaagtt
    11101 ctccacaccg tactgaaaga gggggttgaa gtaggtcatg atgaccagtg gaatctctgt
    11161 ttcaatggtt ttcaaggttt caactaaagc ctgggtagag gtcccgtggg ctaaactgcg
    11221 caagccagct tcttcgataa caggtccatc tgcaacaggg tctgaaaagg gaatacccac
    11281 ttcaattgca gagacaccca aatcttctaa aaagtgaatt gtttcagcaa gaccgtccaa
    11341 acctttctcg tggtcaccag ccatgatata gggaacaaaa attccttttc cagctgcttt
    11401 aatagcattc aatttttctg ttagtgtctt aggcatgagc ttctcccttc tttgctgcat
    11461 ctgcttccaa gcggtctttg acttgaacca catccttgtc cccacgacct gataggcaga
    11521 caatcataga cttttctggt ccaagttctt tggccaattt caccgcaaaa gcgatagcat
    11581 ggctagattc caaggctggg ataatccctt ccacacgaga caagagttgg aatccttcca
    11641 aggcttcttc gtctgtcaca gggacatagc tggcacgttt gatatcgtgg tagtgagaat
    11701 gttctggacc aataccagga tagtccaaac ctgctgagat agagaaggct tcaagaattt
    11761 gaccatgggc atcttggagc acatccatga gagaaccgtg aagaacaccc ggacgaccct
    11821 tggtcaaggt agcagcgtgg tgctctgtat ccacaccaag ccctgctgct tcagttccat
    11881 acatagctac tgactcatct tctacaaagg gatggaagag cccaatagca ttagatccac
    11941 caccaacaca ggctactaga gcatcgggca gattttgacc tgtcatatcg cgatactgtt
    12001 gtttagcttc gcgaccgatg acactttgga agtcacgaac gatttctgga aatggatgag
    12061 gccccaaggc agaaccaagg atatagtggg tatcgtcgat attagccacc catgaacgaa
    12121 gggctgcatt gaccgcatcc ttgagcacgc gcgaaccatc tgttacagcc tcgaccttgg
    12181 ctcccaaaag ctccatgcgg aagacattga gggcttggcg tttgacatct tcctcaccca
    12241 tgtagatggt acattccatg ttaaagaggg ccgcagcagt tgcagttgcc acaccgtgct
    12301 gaccagcacc ggtttctgcg ataattttct ttttacccat acgtttggca agccaaactt
    12361 gtcctaaggc attgttaatc ttgtgggctc ctgtatggtt aaggtcttcc cgtttgagat
    12421 aaatcttggc tccgccaata tgctgggtca agttttttgc gtagtaaaga ggagtttccc
    12481 gccccacata ctggcgcaag agttggttta attcctcttg gaaacttggg tctgcctgac
    12541 tttcacgata ggccttctcc aactccaaaa ctgctgtcat caatgtttct gggacaaaac
    12601 gtccgccgaa ttttccgtaa aatccatctt tatttggttc ctgatatgcc atgctttacc
    12661 ctctctataa atcttctaat cttttcatga tctttttgtc catctgtctc cactccgctc
    12721 gatacatcta ctgcataggg agtaaaatgt tgaattgctt ttactacatt atcttcatta
    12781 aggccacctg cgataaagaa gggctgtgct agtccagtcg tatccagttg accccaatca
    12841 aagggctggc cacttcctgc cacaggggca tcaaagagta gataatctgc ctgagaattg
    12901 gggacatgcc catttccatc tacctgcaca gcctgaatac tggcacaagg caaattctca
    12961 aataaatcat ctgccacctg accgtgaact tgaaccaagt ccaagccaac tttgtcaatc
    13021 gcttccagca gttctacccg acttggtgaa acaaatactc caaccttttt cacatctgaa
    13081 ggaataagct ttgccaactc agctgcctct tctaaagtca cctgtctttt actaggtgca
    13141 aagacaaaac cgatgtagtc ggctcctgct gaaacggctg tttccaccgc ttcttcggtc
    13201 gatagtccac aaattttaac ctttgtcaat ctgcaactcc ttgattctct ggaccacatt
    13261 ttctgcctgc ataagagctg tccctaccaa aattccgtta aagtatgggg ctagtcgttc
    13321 cgcatcctgc cttgtgaaaa tagcagattc agaaatgtac aagcaatcat ctttgaaatg
    13381 tttagccaag tctacactgg tctgcaagtc gacctcaaag gtggtcaagt tgcggttatt
    13441 gaccccgata atctgggcac caagtctgtg agccacttct agttcagcta gattgtgagt
    13501 ttccaccaag acttccagac caagcactgt cgcgtagtcg taaagttcct taagacgttc
    13561 ttctgccaag gctgccacaa tgagcaagat gactgtcgca cctgcattgc gagcgcggat
    13621 gatttgcttt tcatcgatga taaagtcctt gttgagcgtc ggaatctcta cctgactgga
    13681 aatctcccgt agataatcca aatgtccttt aaagaaaact tcatctgtca acaccgaaat
    13741 catcactgct ccgttttctt cataagtctg agcctgttgc acaatatcca catcgagatt
    13801 gatatctccc aaactagggc tagctttctt gacctcagcg attacctgca agcggtcctg
    13861 atgattcttc aaaaattctg ccaagcgata ggtctggcgc agaggctgga tttgctccag
    13921 cttcatctgc tccacctcac gcgccttctg ctctaagatt cgtgctaaaa attcctgact
    13981 catttttggt actcctgtaa cagtctgagt ttttcaaggg ccttgcctct agcaatcact
    14041 tgacgggcca aggcaactcc ttccttgatg ctatcaatct taccattagc atagaaacca
    14101 agaccagcat tcaagactgt cgtttccaag aatggacttg cttcgttttt cagaacgcta
    14161 agcaaaattt ctgcattttc ctgagcattc ccaccacgaa tatcttccat agcatagcct
    14221 tccattccca aatcctctgg agtaaagctt gacaagctga tttcgccatt ttcaagaagt
    14281 gcaatcttgg ttgttccgtt caagccagct tcatccaacc cttctggtcc agcaaccacg
    14341 atggcacgtt tgcgacccat atttttcaaa acctgagctg tactttctag gagttctgga
    14401 cgactaattc caagaagctg tgtttctaaa gccattggat gaatcagtgg accagtcaag
    14461 ttcataatcg ttggaattcc caattccaaa cgagctggca tgatgtattt catagctggg
    14521 tgcatatttt tagcgaagag aaagacgatt ccagttttat caaagacctt acctagttca
    14581 gctggtttga gatcaagatt gattcccaag gcttcgagga catctgcgga accagattta
    14641 gaagaaatcg agcggttacc atgcttggcc atgtgaatac cgccaccagc caagacaaag
    14701 gctgcagttg tggaaatatt aaaactgaaa gacttgtccc cacctgtacc acagttatcc
    14761 atggcatcat gaatctcagt tggaatatgc tgggcatgtc ctctcatgac ttgggcaatg
    14821 gctgtgcgtt cttcaggtgt ttcccccttc atcttgagag ctaagaggag agaagcaatc
    14881 tgcgcttcag ttacacgccc agttacgata cgctcaatga catccgtcat ttccacacct
    14941 gataaatttt caaattttgc tagtttttca ataatctctt tcatcctagt ttcctcactt
    15001 tacaaccttc tcgataaaat tccgaataga agacaagccg tctggcgttc caatgctctc
    15061 tggatggtac tggaagccat aaatcggtag gtttttatgt tgaatcccca tgatggcttg
    15121 gtcatcagtc gaacgagctg tcacttcaaa gtcttctggc atttcctcaa tcaaaatact
    15181 gtgataacgc atgaccgcac gtccatcctc aataccttga tacaaaacag atggcgcttc
    15241 aaagttgata ttgctctgtt tcccatgcat gacttttgga gccaaaccta gcttaccacc
    15301 aaagacttct gcaatggctt ggtgacccaa acaaatccct agaatcggct tcttgcctgc
    15361 aaaatcacaa atcatgtctt ccatctttcc agcatcaact ggccaaccag gaccaggaga
    15421 aaagaccaga ccatctgctt tttcagcttc ttcatacagc ttggaatcat catttctcag
    15481 aacctgaact tctgcaaaat tcccaatgta ttgggccaag ttataggtaa aagaatcata
    15541 gttgtcaatc aataaaatca tggtcttagt tctccaattc tagtcataga ttttgctttg
    15601 ttaatggttt cttggtattc gttttgggcg atagagtcgt agacaatccc tgccccagcc
    15661 tgcacatagg ctctttgatt tttgagaatc atggttcgga tggcaatggc caaatccata
    15721 tcacccgtcg cagacaagta gccgattgct cctgcatata cgccccgttt ttccgtttcc
    15781 agttcataga tgcgtctcat agctcgaatt tttggtgctc cagaaacggt tccagcagga
    15841 agcgttgctt tcaaggcatc catggcagtg agttctgcaa gcaaacgtcc cttgaccaca
    15901 ctggtcaaat gcatgacgta gcggaagagc tccacctcca tatacttagt aacttggaca
    15961 ctggccgttt cagagatgcg gccaatatcg ttacgcccca agtctaccaa cattcgatgt
    16021 tctgctgttt ccttctcatc agagaggagg tcagtcgcca aggccttgtc ttcttcatcc
    16081 gtagcccctc ttggtcgcgt ccctgcaatc ggattggttg tcacgatgcc atttttgaca
    16141 gaaaccaaac tttctggact agctccgatg atttgataat ccccaaaatc atagaaataa
    16201 aggtaattag aaggattagt cacgcggaga tttctgtaga agtcaaatgg atttccagta
    16261 acttctgctg agaaacgctg gctgagtaca cattggaaca tatcaccatt acgaatcaag
    16321 tcgcgagcag tttctaccat tacctcaaac ttatgtggag cgatatgcgg tttgaagtca
    16381 agtggtgata aatccaagtc ttcaaattca tttggagcag gaatgcgtaa ttcctcaagc
    16441 acttggttca aggatttttc caaggcctct tgactgcgct cactataaag tgcatcctct
    16501 atgacatgta tcttctcctt cttgtggtca aagactatat agctctcata gacaaagaaa
    16561 tgcatgtctg gcgtcccaat tgtatcctca gggatttgac caatttcttc ataaagcgaa
    16621 atcatatcgt aacccacaaa accaatggct ccaccaccaa aaggtagctc tgaatggtgc
    16681 tgactcttat gaatcacttc ataaaggaaa tccaagggat cccgatcaat cacttgacca
    16741 ttttgataaa gaactccatt ttcaaactta atctcaaaaa caggattata ggctaggata
    16801 gaaaaacgag ctgtttcctt gtctctcgga atactctcta agataacctt gtgttgcccc
    16861 tttaagcgca tataagccaa gattggtgat aagacatctc catgaatgat tcgttccatt
    16921 gtaatttccc tttcagttct aattctagtt cgtagcgact gtatgaaaaa tccccacgca
    16981 aaataacttg cgtgaggacg aaattcgcgg tgccacctca attataggat ttctcctatc
    17041 tctcattcct gtctcagata tctcctgtaa caggctgtgc gataaagggc actcccttga
    17101 gaatgatgtt ttcttctctc gtttcagatg aacccaactt tacagctttc tctgcttgtt
    17161 ttcagcaacc acaagctctc tgtgagagaa agaactgtaa tttttccatc tattattttt
    17221 tagcttctag tagtctgcaa tcgcagctag gtccttgcct ccacgaccag agacattgat
    17281 gaagagatgt tcatctcggt acacctttat actcttcgaa aatctcttca aaccgcgtca
    17341 acgtcgcctt gccgtaggta tggttactga cttcgtcagt tctatctgca acctcaaaac
    17401 agtgttttga gcagcctgcg gctagtttcc tagtttgctc tttgattttc attgagtatt
    17461 actagctttt ttcgtattag tccagccttt ttgtttgctt ttagtagtag gcaaggagct
    17521 gtagatagaa ctcaagttca tcaaagcgac ttaaggccct aataaaagat aaaccaaacg
    17581 acggatagaa aaaagcccac acacagaata tacttccgtg tgagggcgtt ggtaacgcga
    17641 tgccacctca attataaagg gactatccct ttacatctct gccttgttta acaacaagct
    17701 gcactgtaag gtgtgcgcac cgaattttca ttgtttcaaa ttcattttca aaatcagccc
    17761 actttcacta cttccaacca cctattcaca atcaccacag gctccctgaa gatcaaaaat
    17821 agttactttt ctgatttgtt gaacttattt taatactttg ttttttcttt gtcaagactt
    17881 ttttacgatt tttttgaaaa tatcattcga atgtgaccat gtcttcctta gatcgaacat
    17941 gaacatgtcc cactcgttag aaattggatc caactcaata gaaactgaat ggaggctaaa
    18001 cagaacttat tttagaacac tccatctttt ccactaggat tttcaagaat taaacaatac
    18061 tagaaactct gtctcctaac aaatttagga gaaacttcaa cagatgtgac actttcccct
    18121 ttaataattg ctaaaacacc ttctatcatt tctttagcca atttaacata attgggagca
    18181 attgtagaca aagctggagt ataatactga gaaataggaa tattatcaaa tccaatgata
    18241 gaaatatcat ctggaataag aattcctttc tcatagcacg cacgaatcaa gccctgaacc
    18301 ttttcatctc ctgaaacaaa aataatgtcc ggataatttt gggtagtcaa gtgctgcatt
    18361 gcataagaat aaactgaatc aattgtagat aagccataaa tgacttttaa atccataaag
    18421 taatttttat cattcagaaa agaacgcaca cctctttcac gatccttatt aacatgggat
    18481 tctcctccca taagcaacca catattttta aatttttctt cagttacagc tttcatcata
    18541 tcataagtag cttgaaaatt attattagat acatagacta ctccagacgt ttgagattca
    18601 ccgaaaacaa gaaaaggcat atggttcttc tttaaatact gaattctgat atcatctaca
    18661 ctttcataaa aaacaataac accatctact aggctacctg tgcttgatat aattgaatta
    18721 ctaattgtat cctcctctcc aaagtactca actatagcat taacaccaaa ttctttacac
    18781 gtccgtaaca ctttatctaa cagcgtatga aaccaaatta aaggaaaaga gtcgattttt
    18841 tttacagaaa tcaatatatt tatagcttct tttttagtta aattttttgc atacgcattt
    18901 ggaatatacg acaattcctc tataactttt tgaatcgctt gataagtttc ttctttaaca
    18961 tttactccac cattaataac tcgtgaaact gtttttggag aaaaacctga taaacgtgca
    19021 atatcataaa tagttacctt tttcccattt atatttttca tttcagtcct ccattacgaa
    19081 cattctaata ttactataca atatttaatt ttttttaaca agagaattta gtaaattatt
    19141 taagatccac aaattcacaa aattaatttt acaaatattc tttcccttca aaaaagttta
    19201 aattgcattt cacaccttta tttttaagaa tgtttccaac ttcacgacaa ataaattcat
    19261 atgagaaaaa actaccataa aattgtagat taactttttc agtaaaatgt gtaggattta
    19321 taaaaacata taatagcctg tcaatttaac attttaacat agagttaatt ttttctttaa
    19381 agataacatt tgttatcaac tcatcaggag gtaaatgaaa ggcaaacacc atttcacaaa
    19441 tatcataaaa agaaataaat ttgtatactt gtatcaaaca attattatca aaatattcta
    19501 ttttacctaa atcaaaattg attttataat ctttcataaa aacctctgag caaaaatcta
    19561 ctcaaaaatt agatgattaa aacatctaaa aaacaaaagg acaaaaacat ctgtcccttt
    19621 gtttactaaa tttcagctaa tttcttcgac ataaataaca cctacaatat tagcaatttc
    19681 ttccatcagt cgaagatgtt caaatctacc tgataattcc agagtaataa atgacgctat
    19741 ttttttgtcc ggaacatcaa agtattcaat tctgtcagaa ttaacatctc caaacgctgt
    19801 tcttgaatcg gtcattctga taccattttc tgcacaataa accaatacac gattataggc
    19861 ttctgtagat ttaactacta tatacaattc aatcatttta gaacgatttt gcagatattt
    19921 ttttagtggt tggaacatgg atatcacacc ccaaacagaa atggctacta aaagagctcc
    19981 ctcataaaaa cctactccaa tagctaatcc aattcctgcc gaagcccaaa tgcctgctgc
    20041 agttgtcaga cctgtaattt tctttttatc tgtaataaga atcgttccag cgcctagaaa
    20101 acccacacct gatataactt gagctcctaa tcgtgtagga tctcctgtcc caaatttata
    20161 agatacgtat tcattcgtca tcataatcaa acatgcagct agacaaacaa tactataagt
    20221 tcggatgcct gcaggctggg atttgctccc tctctctaaa ccaattatac taccaatgac
    20281 tactgataaa acaatcctga caactatttc aatatttgat aacccaagac tagtggctgt
    20341 catgattatt tccttacttt acgccccggt ctttgtgtga agtataatac cgttccagaa
    20401 ataatcatca gaacaattgt ataaacaaat accagagctt gtgcattaga tgttgctgtt
    20461 tcatcacctg cagatcgaat cgtaatacct aatggttgag ctaggggatg gtaaaggaat
    20521 acagataagt cgaagtcagt taataaagag ttaaagttta aagcaataac agagagaaca
    20581 accggtaaaa taaatggaat gataaccttc atcatagtat aaaaaggtga agcacccata
    20641 cttcttgctg catcttccat ctcatcatca acactaaata aaatagcacg taccattcta
    20701 taagaaaatg ggatttttac aactatatat gcaataagta gaattaccaa actacctacc
    20761 aaaatctgat tcaagacaag aaattgtggc tgattaaaag taaataataa acttactgct
    20821 aaaagtgtac ttggtagtaa ccaaggaagt agagcaccat attcaaataa gaaatcaaaa
    20881 cgagatttat gttttctgac aacacgagca aatacaactg cgagaattgt tgctgttgtc
    20941 gcagcaataa tagaataaat aaagctgacc aagaatggag agaatgccgc actattacta
    21001 aagaataagc gataattttc taaagtaaag tttgataatg ttaagttacc tgtttgaatt
    21061 gcaactggat ctgtaaatga gtataatact ataaaaatta gtggaagcat gaaaactgtg
    21121 aacaatccat atgctacaat gtgagcaatg atattccaag gcttagacgc aattttttgt
    21181 tttttaagag gcgctttagt cttagagata gaaatataat ttccaccttt ttctatctta
    21241 ttcatgatag taagcaaaat tgtagttgca atacctaaaa taattgcaag taaggcagct
    21301 aaatcacgag aattccccat ccctgcaaat gtaataatca ttggatttat agtttgaaat
    21361 tctttaccac caacaatcat gggtgctgct actgcagata aaccactaag aaaaaccata
    21421 atagtaagtg caaatagagt tggaattaag gttggtaaca ctacttttcg gaaaacagta
    21481 aatggttttg ctcccatatt tcgagcagcc tcaatagtgt gatagtcaac gcttcgaatt
    21541 gtatttgtta aaaacaatgt atgattagca gttcctgaaa atgtcataat gaataagact
    21601 gcaccatacc caataaacca gttagagtct aaagaaggga taacattttg taaaaatttt
    21661 gtaatcaatc cataaggacc atagacaaat ttatatccag tcgctaaaac cactcctcca
    21721 taaattaaag aggtcatata acctaatttt aaaattttag cacctttaat atcaaagtac
    21781 tctgtaaata gaacacaaag aatacctacg acattaactg taataatgag tgaaaatgct
    21841 aacttaaaac tgttcataat actctgaagt gccctctgag attttagaac acgatgtaca
    21901 gcatcaaggg aaaattctcc tccttttaca aatacattca ctactagatc aaagtttgga
    21961 taaataataa atgttactaa gaaccagatt aatcctaaac gaataagcca atcttttaaa
    22021 tttaatttat gacgcatact gcacctcctt aaaattgcag aacgtctgat ggtgtgataa
    22081 ataattccac actttctccg acagatctaa tagcagcctg actatcaata cttgttacat
    22141 taagaatctg actttcagaa acttttattg tatagtgaat tgtaactcca gaaaactcaa
    22201 catcaataat tgtccctttt agaataaaat cttgttcagt ttcacgattg aatcgaactt
    22261 tctctaatcg aatgtatcct tttttatcct ctaagaaaac gcttgtattt ttcaataata
    22321 cttcgtggac tgtttcatcg gtcaaaacat taatatctcc aataaaatca catacaaatt
    22381 cagtttgaga attatgataa atctctactg gtgtaccgac ctgttcgatg tatccattgt
    22441 taaagactgc aattctatca gataaagtca aggcttcctc ttgatcatga gtaacatata
    22501 aagtagtaat acctaactct ttttgaagtc ttttcaactc ttttctcaaa tctacacgta
    22561 attttgcgtc aaggtttgac aatggttcat ctagacaaag aattttaggt tcaagaacca
    22621 gagcacgagc caatgctacc ctttgttgtt gacccccaaa taattctgat acattacgct
    22681 gtaactgttg atcagagatc ttaatttttg ctgccactgc tgatacttta gctttaataa
    22741 catctggagc taccttctta acttttaaac caaatgcaat attatcaaaa acagtcatag
    22801 ttggaaatag cgcataagat tgaaatacaa taccaattcc acgcttttca ggttccaaat
    22861 gagtgacatc tgttccatta acttcaatac ttcctgatga tggatctaaa aaacctacca
    22921 atgctctcaa agtagttgat ttaccacatc ctgaaggccc aagaaatgta aagaattccc
    22981 cttcatgtat atctaaattc agattatcaa ttgcaacaaa atcaccatat ttaatttgaa
    23041 tattatcaaa tttaatcatc tcactaactc cctctattac taaaccaaaa gcctctcttt
    23101 atttcttcct taaatttaga aataatagag agacttggac ataaaaaata actcttattt
    23161 cttattgtac gtattctaat tcagcttttt ctacccattc atccaaatgc tttccaacag
    23221 cttcccagtc aatattttgt ggtttcactt gatcaacaaa ttttttcgta tcttcaggta
    23281 actcttttag ggcatcttta tttgcaggaa tagatccaaa ttttttacta tattctactt
    23341 gaatttctga ttgaccaaac caatcaataa attctttagc taacgcttgt tttttactag
    23401 tgcttaaaac catagtttgt tcagttacaa atggtacacc aatctcagga gtcataactt
    23461 tgaattcaac attttgttct ttttgtccaa ttaacgatcc agaaccccag atcataccgt
    23521 attgaattgg gctttcttta tctaacgctt taacaactga gctttcacct ttttgaagag
    23581 tataggcatt tgcaaagtat tcttttgcaa cttcccatcc tttttctgat acgcctaaat
    23641 ctcctttttc atcaaggtaa cgaactaaga tacttgctag aattgcccgt cctgtaccac
    23701 cttgaagacc ataaattgaa tatttacctt tatacttact acctaattca gtccaatctt
    23761 taggcatttc ttttacatca ggcgccccaa ttaaaactaa tggttgaaca atcacaggat
    23821 tataataatt atctttatct gataaagatt gatcaatttt atctaaccat ttaggcttgt
    23881 actgtactag taatttttga tctctaattt tatttgagtc aacagcacca attccaaata
    23941 ccatatctgc aactgcatta ttcttctcag caataacacg gtctgctaat tgagcgccag
    24001 cgatatcaac catttttata ttaaaaccag cttcttttgc tttagcagtt aaccaatcac
    24061 cacgaccatt tgagactgag ttcgaataga taactaattc ttgactttta tcagcttttt
    24121 cttcagatga agaagcagtc gtagaatttg aacctccaga gcaagcagca agtgtagtaa
    24181 gagcaactcc cgttgcaagt acagtagacc aaactttcat ttttttcatg ataagttctc
    24241 cttttttatt attttattta aatttttcgt gatatggaac aaattgtctc atatcttcaa
    24301 atacagtata gtcaatacgg tttacagtaa tagttggaat cttctctaat aaaatttcag
    24361 ttaattctgc tctgacttta gtaaactctt cttcctcctc ttcggttaga ggaatccgaa
    24421 gatacccaat tgaaatatgg aattgatatc tatcatgatt agggaaacaa acacctgctt
    24481 tttctgagac ataagtacga atttcttcta atctctttgc agaagcttca tctgcaggtt
    24541 caactagtat gttttgtttt cccatttcag ttatacgcat atgaatttct tcatccaaca
    24601 atggaaaaat ttcaagttgt ttagcaaagt aatcatgtat ttcctgtaaa ggtgtatcta
    24661 gaggaagatt actgctccaa aactccgttt cacgattttc atggcacaac aattcaatta
    24721 cagtcatgtg aatagaattc cttggagtta aagtaaactt atcgataaat ggtaattctc
    24781 tataacgtga ttgaataata tcaacaactt ccatcaaatc ttgtttagta taaagatttg
    24841 ctacaactgt attcccaggg aaatgattaa attccccatt ctctttgaac ttaatttttg
    24901 ttaagttttt catataaaga ccttcttttt tatatttgac atcggtgtca ctatgtttac
    24961 attatacaat gaaaccgttt cctttgtcaa gcgctgtcaa acattttttt taatttatct
    25021 ttcattaaat atgcatttca ttaaaaggtt aagtaatttt tccaaaatac agcactcata
    25081 tagacagtat catcaattat agccattggg attttttgat tgccaattcc atgtatctct
    25141 acacatgtct tcaatcgatt ttgttgtcct ccaatttaat tccttatatg ctctttgtct
    25201 gcatttgcat aacaagttgc aacgtctcct gaacgtcttg gaactatttt ataaggaata
    25261 gggatcttat taacactttc aaatgtattt acaagttgta atacactagt gccttctccc
    25321 gagcataggt tatagatata aacatctgtt ttttcagata ctttttctaa agcttttata
    25381 tgtcctattg ctaaatctac tacatggatc ttttatctca tttttccctt tttcaaataa
    25441 gttatctact ctatgatcag ttatttccat ttcgtttact aacatgacgc agtcacctag
    25501 catcatatac tccaactttt tttctgaaag tttagcaaat attggtaagc gataatatag
    25561 tatgttgaaa ctagaatagt acacctctac ttctaaaaca ttgttagaaa tcgatttgac
    25621 tgtcct
//
LOCUS       DAVAGB010000027        24263 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVAGB010000027 DAVAGB010000000
VERSION     DAVAGB010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24263
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.027"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            5..75
                     /locus_tag="VQO19_001281"
     tRNA            5..75
                     /locus_tag="VQO19_001281"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37..39,aa:Gly,seq:tcc)
     gene            110..183
                     /locus_tag="VQO19_001282"
     tRNA            110..183
                     /locus_tag="VQO19_001282"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:144..146,aa:Ile,seq:gat)
     gene            266..355
                     /locus_tag="VQO19_001283"
     tRNA            266..355
                     /locus_tag="VQO19_001283"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:302..304,aa:Ser,seq:tga)
     gene            366..439
                     /locus_tag="VQO19_001284"
     tRNA            366..439
                     /locus_tag="VQO19_001284"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:400..402,aa:Met,seq:cat)
     gene            443..515
                     /locus_tag="VQO19_001285"
     tRNA            443..515
                     /locus_tag="VQO19_001285"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:476..478,aa:Phe,seq:gaa)
     gene            528..608
                     /locus_tag="VQO19_001286"
     tRNA            528..608
                     /locus_tag="VQO19_001286"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:562..564,aa:Tyr,seq:gta)
     gene            613..683
                     /locus_tag="VQO19_001287"
     tRNA            613..683
                     /locus_tag="VQO19_001287"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:645..647,aa:Trp,seq:cca)
     gene            698..770
                     /locus_tag="VQO19_001288"
     tRNA            698..770
                     /locus_tag="VQO19_001288"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:731..733,aa:His,seq:gtg)
     gene            781..852
                     /locus_tag="VQO19_001289"
     tRNA            781..852
                     /locus_tag="VQO19_001289"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:813..815,aa:Gln,seq:ttg)
     gene            862..945
                     /locus_tag="VQO19_001290"
     tRNA            862..945
                     /locus_tag="VQO19_001290"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:896..898,aa:Leu,seq:caa)
     gene            complement(1056..1787)
                     /locus_tag="VQO19_001291"
     CDS             complement(1056..1787)
                     /locus_tag="VQO19_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET1349550.1"
                     /translation="MAKLYAISDIHGYLDEFRDALNKVNLNDKDNRLFLLGDYLDNGL
                     QSFQVISKIIELEEVYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEEL
                     NYIFKSNANNFETGVRNEIKNNIKFNPFINWFKKRYRDKRYYETDTQIFVHAGIDEEA
                     GKLWKELTSSEIFTNKFPITTGRFHKAIISGHIASWEVAKDRRYLGKIYYDSKSHYFI
                     DGDVTNSKTIPILCYDTITQKYHFL"
     gene            complement(1780..2016)
                     /locus_tag="VQO19_001292"
     CDS             complement(1780..2016)
                     /locus_tag="VQO19_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HET1349551.1"
                     /translation="MNNVVTTQISIQLSQELNSLLNAIVEENNTTKTDFIRQAVIEKI
                     EDMYDIKVADEAYKKWVECGKKAISHEEMMRRYG"
     gene            complement(2232..2669)
                     /locus_tag="VQO19_001293"
     CDS             complement(2232..2669)
                     /locus_tag="VQO19_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET1349552.1"
                     /translation="MDTSQVIKAHEVAKKAHFGQIDRAGIDYIKHPETVASFVATDEE
                     KAVAYLHDVIEDTSLTLLDLKKEGFSKNIIEAVDILTKKKGQDYQSYLNLVKKNELAR
                     VVKLADLRHNSDLTRLPLITEKDLERNKKYSSAIRFLRAKKKS"
     gene            complement(2710..3843)
                     /locus_tag="VQO19_001294"
     CDS             complement(2710..3843)
                     /locus_tag="VQO19_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET1349553.1"
                     /translation="MAIRKGKDGNWVVDISNGFDPITLKQRRLVRKGYKTKKEAIEAE
                     HYLRSVELKERFYGAKITISILYELLKEEDSINHRKASYINTQDNNYNKHIKDYFSMV
                     DNVGKLTYEDIYQFREHLRQKVAKNSDKPLSTNTINKIMILLKKIFDVGLRKGYYSSN
                     PAKLIKKLPIEKTKMQFWTVKEFQKFLTLFEPEEYNIKLLFTVLFFTGLRLGEALALT
                     WQDIDFSSNTIHITKSVYVNKGVTHISTTKTKAGTRRIVINKKLSQELQDWEKRQKHL
                     LEQFTNNSLTLQVFQNSPITITKNAIEKQYKKIIERDSTLKKIRIHDFRHSHASLLIN
                     QGEDYLVVKERLGHASITTTIDTYSHLYPSKQKDLADKLDDLL"
     gene            complement(3847..4050)
                     /locus_tag="VQO19_001295"
     CDS             complement(3847..4050)
                     /locus_tag="VQO19_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HET1349554.1"
                     /translation="MIATVTKNDLIALGFSEGTSKRIIRQGKELLITRGFTVYQNKRI
                     GTIPATIATELLGFDVQNSTLKE"
     gene            complement(4064..4846)
                     /locus_tag="VQO19_001296"
     CDS             complement(4064..4846)
                     /locus_tag="VQO19_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HET1349555.1"
                     /translation="MTSYNKKIVRTSSYIEIWEYEKPIFSKGKSILDTNTENKEKAKR
                     RTFDELTPLEQEQRLERMKKTRLEAKWNLLRLVDCNFDDTTSFLTLTTKENISDRNHF
                     KDLLKTFIKRFNYHIFNTKKSKLKYIAVLERQKRKAWHSHILLFSVPYIPHKQLLELW
                     GHGAVRINKVDVDSKENRGRYVTKYFEKGIGQELLENFGKQAYFSSRNLKKPDEDKFY
                     TYEDFNYDSSVVLYETEYTSKVYKDGQYFDNHVKYKKIRLDE"
     gene            complement(4944..5717)
                     /locus_tag="VQO19_001297"
     CDS             complement(4944..5717)
                     /locus_tag="VQO19_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET1349556.1"
                     /translation="MKTLLIGDLHLKSQLILPIVDKIIQTHNIKRIIFLGDYVDLHGQ
                     TNNIQLYAKDLTFLYSWKIDKEQNGIDVINLIGNHDAYYLLGEQAPFSIQNLEVFFAI
                     QQLLQDLNLQVAYQLDDYLVSHAGFNLIFDPKEWHFNLYTKEHEEELDILAYTIGPMR
                     GGKALGGSPLWAHFRELELLPNQDFPKQIVGHTPKESIDISKNVIGIDTFSLYIDKDN
                     KYQFIGNGDLLVYDQGHFEVISTDWATDKILKQLPQPQI"
     gene            complement(5884..6273)
                     /locus_tag="VQO19_001298"
     CDS             complement(5884..6273)
                     /locus_tag="VQO19_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006268423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349557.1"
                     /translation="MQTFNYDDFKNEKGIVSFSEAEQIYSSLLNSSNQLDKEFQEEWT
                     TFVLLCVEYASARGKWLTLSREEKLANDESRTVTHNKVIYQLKILKGLASEQGNDVAW
                     FEQFNDDRKRIGDFACYVAYIYALNAR"
     gene            complement(6431..7114)
                     /locus_tag="VQO19_001299"
     CDS             complement(6431..7114)
                     /locus_tag="VQO19_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HET1349558.1"
                     /translation="MFKLRQSADLTRNNIISCYKLKIMHWLILSISACILFSTIVNIR
                     APTFVQILFIFLGGFIIYKIHLKIKIFRYDLEHYLIIRESLLYVLHTNRLYTTYKDST
                     GQEKVIRSAILEYELDRQKGHVLIKALIRGDEFSHKLKSLEDELCGVLELELEKKVLR
                     PSVAEYHFYYIKPKRLVLQSHNQRQEIDSLDIDLGYGVNYNPIKCPHILVSGGTGRGK
                     SVFISFLIA"
     gene            complement(7120..7338)
                     /locus_tag="VQO19_001300"
     CDS             complement(7120..7338)
                     /locus_tag="VQO19_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349559.1"
                     /translation="MSDNLKAYIFLLGFLILAGIAIFILPQGHFFSVSALVLGCIPLF
                     ISIYYFAKIKLLGFYELLKELLDKIKGI"
     gene            complement(7368..8126)
                     /locus_tag="VQO19_001301"
     CDS             complement(7368..8126)
                     /locus_tag="VQO19_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET1349560.1"
                     /translation="MKKIKASTWNINQRSGQGKQIPEMIVHELAKQNSEIVCLTEYVK
                     TDNPSLFCTKLQDMGYKIFEDVRTIDFGNQILIAIKNDLVNDCQVITIDNDDNNPNFL
                     HVRVTIEGQELNIIGVRIKVGGENIFQDFKHRKSQLDKLISNLPATHENTIVLGDFNN
                     GYFQQNDDIHSYQGKAREFYSYPLLKSEMNKAGLTVHTPSEETSWKYCKLDHIFANIP
                     ISNENYSWEFLKNADYNSRVGFPDHAILSASISL"
     gene            complement(8144..8376)
                     /locus_tag="VQO19_001302"
                     /pseudo
     CDS             complement(8144..8376)
                     /locus_tag="VQO19_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000982220.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8659..9120
                     /locus_tag="VQO19_001303"
     CDS             8659..9120
                     /locus_tag="VQO19_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349561.1"
                     /translation="METRNEKFRRLSEARMTKVFSILNILRNQSDKSKYTFSKSDIEE
                     LFGALEQKGEEIKEFFTSPITIKTINLKKSFHYSMVDTSNDKEVAFKKLSTARVEKIF
                     SLMNLLANLSNKSNYNYSDWEVEELFSAYDEEVRKCKVFFEEKRTVFKYSE"
     gene            9396..10673
                     /locus_tag="VQO19_001304"
     CDS             9396..10673
                     /locus_tag="VQO19_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HET1349562.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKFLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            10749..12233
                     /locus_tag="VQO19_001305"
     CDS             10749..12233
                     /locus_tag="VQO19_001305"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HET1349563.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALCEKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGDKINFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPVRHKTTVAAADMQAAVEAYLGL"
     gene            12294..13574
                     /locus_tag="VQO19_001306"
     CDS             12294..13574
                     /locus_tag="VQO19_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET1349564.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYEKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            13578..14198
                     /locus_tag="VQO19_001307"
     CDS             13578..14198
                     /locus_tag="VQO19_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET1349565.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            14364..15506
                     /locus_tag="VQO19_001308"
     CDS             14364..15506
                     /locus_tag="VQO19_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET1349566.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETTRPVEEATPQETTPAEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKVISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVAERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            15912..16250
                     /locus_tag="VQO19_001309"
     CDS             15912..16250
                     /locus_tag="VQO19_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET1349567.1"
                     /translation="MTRYQILLFLLEHSPCNQMAVQERLKIDQAALTRHFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            16261..16619
                     /locus_tag="VQO19_001310"
                     /pseudo
     CDS             16261..16619
                     /locus_tag="VQO19_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
     gene            16726..17343
                     /gene="pcp"
                     /locus_tag="VQO19_001311"
                     /pseudo
     CDS             16726..17343
                     /gene="pcp"
                     /locus_tag="VQO19_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(17371..18228)
                     /locus_tag="VQO19_001312"
     CDS             complement(17371..18228)
                     /locus_tag="VQO19_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HET1349568.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQRFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            18358..19500
                     /gene="tgt"
                     /locus_tag="VQO19_001313"
     CDS             18358..19500
                     /gene="tgt"
                     /locus_tag="VQO19_001313"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HET1349569.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            19598..21415
                     /locus_tag="VQO19_001314"
     CDS             19598..21415
                     /locus_tag="VQO19_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HET1349570.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     ASVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGIVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILVAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            21568..22719
                     /gene="nagA"
                     /locus_tag="VQO19_001315"
     CDS             21568..22719
                     /gene="nagA"
                     /locus_tag="VQO19_001315"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HET1349571.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            22882..23940
                     /locus_tag="VQO19_001316"
     CDS             22882..23940
                     /locus_tag="VQO19_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HET1349572.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            complement(23989..24263)
                     /locus_tag="VQO19_001317"
                     /pseudo
     CDS             complement(23989..24263)
                     /locus_tag="VQO19_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         7185 a         4178 c         5044 g         7856 t
ORIGIN      
        1 tttagcgggt gtagtttagt ggtaaaacta cagccttcca agctgttgtc gcgagttcga
       61 ttctcgtcac ccgctttgaa ctttgttctt tgtaccaagt ttttgacttg ggcgcgtagc
      121 tcaggtggtt agagcgcacg cctgataagc gtgaggtcgg tggttcgagt ccactcgtgc
      181 ccatagtgtt tagtccatta ctaggggatt ggaatattat ctgttcacta agaggacacg
      241 ggcttgttcc cgtataaact attttggagg attacccaag tccggctgaa gggaacggtc
      301 ttgaaaaccg tcaggcgtgt aaaagcgtgc gtgggttcga atcccacatc ctccttttat
      361 attaacgcgg gatggagcag ctcggtagct cgtcgggctc ataacccgaa ggtcgtaggt
      421 tcaaatcctg ctcccgcaat aaggctcggt agctcagttg gtagagcaat ggattgaagc
      481 tccatgtgtc ggcggttcga ttccgtctcg cgccatttat atattttgga agggtagcga
      541 agaggctaaa cgcggcggac tgtaaatccg ctccttcggg ttcgggggtt cgaatccctc
      601 cccttccatt ttacgggcat agtttaaagg tagaactaag gtctccaaaa ccttcagtgt
      661 gggttcaatt cctactgccc gtgttaatag aattatggcg ggtgtggtga agtggttaac
      721 acaccagatt gtggctctgg catgcgtggg ttcgatcccc atcactcgcc tattttatat
      781 tggggtatag ccaagcggta aggcaaggga ctttgactcc ctcatgcgtt ggttcgaatc
      841 cagctacccc agttactatt tgccggcgtg gcggaattgg cagacgcgct ggactcaaaa
      901 tccagtgtcc gcaaggacgt gccggttcga ccccggccgc cggtatagtt gaaaagacaa
      961 ggtttctaag ccttgtcttt ttgttatgtc ataagaaatt tcttggaatt gttactaata
     1021 attactaatt tcatataaaa gcacatgatt aaaagttata gaaagtgata tttttgggta
     1081 attgtatcat agcaaagaat aggtattgtt ttgctattcg ttacatctcc atcaataaaa
     1141 taatgacttt tactatcata gtaaatctta cccaggtatc ttctatcttt agctacttcc
     1201 caagaagcaa tatggcccga aataatagct ttatgaaatc taccagtggt aataggaaat
     1261 ttgtttgtaa atatctctga actcgttagt tctttccaaa gctttccggc ttcttcatca
     1321 atgccagcat gaacaaaaat ttgggtatca gtttcataat agcgtttatc cctatatcgt
     1381 tttttaaacc agtttataaa tggattgaat ttgatattat ttttaatttc atttctaaca
     1441 cctgtttcaa agttgttagc attcgattta aaaatatagt tcaattcctc tggagagaag
     1501 aagcttttta ttgtttctgg aaatgctgaa gcagtaggct tatctaaaat caaccaatca
     1561 taaaaccatt cttcatgatt ccctagaaga gtaataattt gattaggata aacttcctca
     1621 agttcgatta ttttggaaat gacttgaaaa gattgaagtc cattatcaag ataatctcct
     1681 agtaaaaata ggcgattatc tttatcgttt aaatttactt tattgagagc gtctctgaat
     1741 tcatccaagt atccatgtat atcagatatt gcgtataatt tagccatagc gtctcatcat
     1801 ttcttcatgt gagatagctt ttttgccaca ttcaacccat tttttataag cttcatcagc
     1861 gaccttaata tcatacatat cttcaatttt ctctataaca gcttgtctaa taaagtcagt
     1921 ctttgttgta ttattttctt caacaatagc atttaataaa gaatttaact cttgactaag
     1981 ttgaatagaa atttgtgtag taacaacatt attcatataa cagccaccta atagttattt
     2041 tagatacatt atactcctag tctaaaagtt tctcaataaa aaatttcact ttttatagtt
     2101 atttatttta ataaaattgt agtatctgca aggatgtgcc agttcgagac cgaccgccag
     2161 tatagtaata aagacaaagt ttataagcct tgtcttttgt tttctcttta taaaatttta
     2221 tagtttagtt actaactttt tttctttgct cttaaaaatc taatagcaga actgtatttc
     2281 ttatttctct ctaagtcttt ttcagtaatt aatggtagtc ttgttaaatc tgaattatgc
     2341 cgtaaatccg ccaactttac aactctagcg agttcatttt tctttactag attgagataa
     2401 gattgataat cttgtccttt tttctttgtg agtatatcga cggcttctat aatgtttttt
     2461 gaaaaacctt ccttttttag gtctagtagg gttagtgaag tatcttcaat tacatcatgt
     2521 agataggcga cagctttctc ttcatcagtt gcgacaaaac tagctactgt ttcagggtgt
     2581 ttaatgtagt caattcctgc tctatcaatt tgtccaaagt gtgctttttt agctacttca
     2641 tgtgctttta ttacttgtga tgtatccatg atttaattat aaactttcca tttataaaac
     2701 tcaattactt tatagtaaat catctagttt atcagctaaa tccttttgct tacttgggta
     2761 caagtgagag taggtatcaa tcgtggttgt tatagaagca tgtcctagtc gctcttttac
     2821 aactagataa tcttcccctt ggttaatcag cagggaagcg tgtgagtgcc taaaatcgtg
     2881 tatgcgtatc ttttttagtg tgctatcacg ttcaatgatt ttcttgtact gcttttcaat
     2941 agcatttttc gtaattgtga taggactatt ttgaaacact tgtaatgtta ggctattgtt
     3001 ggtaaattgc tctaatagat gtttttgtcg cttttcccaa tcttgtaatt cttggcttaa
     3061 ttttttattg ataacaattc ttcttgttcc tgctttagtt tttgttgtgc tgatatgagt
     3121 tactccttta ttaacataga cagatttcgt gatatgaatt gtattacttg aaaagtcgat
     3181 gtcttgccat gttagggcaa gagcttcccc aagtcttaat cctgtaaaga atagaacagt
     3241 aaagagtagt ttgatattgt attcttcggg ttcaaatagt gtcaaaaact tctgaaattc
     3301 tttgactgtc caaaattgca tttttgtttt ttcaattggc aactttttta tcaattttgc
     3361 tggattggag gagtaatagc cttttcgcaa accaacatca aaaatttttt tgagtaaaat
     3421 catgattttg ttaatagtat ttgtgcttaa cggtttatca gaatttttag ctactttttg
     3481 cctaagatgt tctctaaatt ggtagatgtc ttcataggtt agttttccga cattatcgac
     3541 catagaaaaa taatctttga tgtgtttgtt gtaattatta tcttgtgtat tgatatagct
     3601 tgcttttcga tgatttatgc tatcttcttc cttaagtagt tcatatagta tggagatagt
     3661 tattttagcc ccatagaagc gttcttttaa ctctacactt cgtaagtagt gttctgcttc
     3721 aatagcttct tttttcgtct tatagccctt tctgacaagt ctacgttgct ttagtgttat
     3781 tgggtcaaaa ccgttgctaa tatcaactac ccaattaccg tctttacctt ttctaattgc
     3841 catattttac tccttgaggg tactgttttg aacatcaaaa ccgagtaatt cggtagcaat
     3901 agtagcaggt atagtaccaa ttcgcttgtt ctgatagact gtaaagcctc gggttataag
     3961 tagctctttc ccttggcgga taatacgttt agatgttcct tcagagaaac cgagggcaat
     4021 taggtcattc ttagtaacag ttgctatcat gtgacttact cctttattca tctagtctta
     4081 ttttcttgta ctttacatga ttatcgaaat actgaccgtc tttatagacc ttactagtgt
     4141 attccgtttc atatagtacg actgaactat catagttaaa atcttcataa gtgtaaaatt
     4201 tatcttcatc aggctttttc aagttgcgtg atgaaaaata tgcttgcttt ccgaagtttt
     4261 ccaacaattc ttgtccaata cctttttcaa aatactttgt gacatatcga ccgcgatttt
     4321 ctttgctgtc aacgtcaact ttatttatcc gtactgctcc atgcccccaa agttctaata
     4381 attgcttatg tggaatatag ggaacactga atagcaaaat atgactatgc catgctttac
     4441 gtttttgcct ctctaatact gctatatatt ttaatttact tttcttggta ttaaaaatgt
     4501 gatagttaaa gcgtttaata aatgttttga gtaagtcttt gaagtggttt ctatcgctga
     4561 tattttcctt agtggtcaat gtaagaaaag aagttgtatc atcaaaatta caatcaacta
     4621 gacggagtaa gttccacttg gcttctaagc gagtcttctt catacgttca agacgttgtt
     4681 cttgttctag gggtgttagt tcatcaaatg ttctgcgttt tgctttttcc ttgttttcag
     4741 tattagtatc taaaatagat tttccttttg aaaatattgg cttttcatat tcccaaattt
     4801 caatatagga agaagtgcgg actatttttt tattatatga ggtcatatat catgtgatcc
     4861 taagcaccgc tccgctaaac acacttccag cttgctgact gcttgtcggc agttttgctt
     4921 aggtacatga tgagaagtag ctattaaatt tgtggttgtg gtaattgttt taatattttg
     4981 tctgttgccc agtctgttga aatgacctca aaatgtcctt ggtcataaac gagcaaatct
     5041 ccgttaccaa taaattgata tttattatct ttgtcaatat ataatgaaaa agtatctata
     5101 ccaataacat ttttagaaat atcaatagat tctttagggg tatgtccaac aatttgttta
     5161 ggaaagtctt ggttgggaag cagttctaat tctctaaaat gtgcccataa aggagaaccc
     5221 ccaagagctt tcccaccacg cattggtcct attgtataag ctagaatatc taattcttct
     5281 tcatgctctt tggtatagag gttaaaatgc cattcttttg ggtcaaatat cagattgaaa
     5341 ccagcatggc taactaaata atcatctagt tgataagcta cttgtaaatt caaatcttgt
     5401 aataattgtt gaattgcgaa aaagacctct agattttgaa ttgagaaagg agcttgttct
     5461 cccagtaaat aataagcatc atgattacct ataagattaa ttacatctat tccattttgc
     5521 tctttatcta ttttccaaga gtataaaaaa gtgaggtctt tggcataaag ttggatattg
     5581 ttagtttgac catgtaaatc aacgtagtca ccaagaaaaa tgattctctt aatattatgt
     5641 gtttggataa ttttgtcaac aatgggtaaa atcagttgag attttaagtg taaatcacca
     5701 attaataacg tcttcatata tattcccctc tttatttttg atattagtct aagaatcgaa
     5761 ttaagttata gcacattgtt tcggtgatag ataaaaagaa ttaattattc ttaagatgtt
     5821 atttaataat ttccatgaat atcagaaata gagtaatata tagccataat atcctctaat
     5881 tgtctatcga gcatttaagg catagatata agctacatag caagcaaagt cgccaatacg
     5941 ttttctgtca tcgttaaatt gttcaaacca agcaacatca ttgccctgtt cacttgctaa
     6001 accttttaaa atctttagtt gataaataac tttattgtga gtaacagttc tagattcatc
     6061 attggcaagt ttctcttctc ttgagagtgt gagccattta ccacgtgcag aggcatactc
     6121 tacgcataga agtacaaatg ttgtccattc ttcttgaaat tctttatcaa gttgattgga
     6181 ggaattaagg agactagaat agatttgttc tgcttcagaa aatgaaacaa tccccttttc
     6241 attcttaaaa tcatcgtagt taaaagtttg cattgtaaaa ctcctttata tattatctaa
     6301 tcttagctat tttgttacag gtaaaacatc agaacaagcg aaccacaagt ttccattgaa
     6361 ttgccctaca tttaaatctt taagagtaac aggacaagtt ttgttgttcg ccatctcttg
     6421 aacagaagca ctaggcgatc aggaaagata tgaagacaga ctttcctctc cctgtccctc
     6481 ctgatactaa aatatgtggg catttgattg ggttataatt tacaccatat cctaaatcta
     6541 tatcaaggct atctatctct tgtctttggt tgtgagattg tagaactaac ctttttggtt
     6601 ttatgtaata gaaatgatac tctgcaacac taggccgaag aacctttttc tcaagctcta
     6661 gttcaagcac gccacaaagt tcatcttcaa gagatttaag tttgtggcta aactcgtccc
     6721 ctcttataag agccttgata agtacatgac ctttctgtct atctaattca tattctaaga
     6781 ttgcacttct aataactttt tcttgtccag tactatcttt atatgtagta taaagtctat
     6841 ttgtgtggag tacataaagt aagctctcac gtataataag gtaatgctct aagtcatatc
     6901 gaaaaatttt tattttcaga tgaattttat agataataaa tccacctaaa aatatgaaga
     6961 gaatttgaac aaaagttgga gccctaatat taacaatagt agaaaataga atgcaggcag
     7021 agatacttag tatcagccag tgcattattt ttagcttata acaggaaatt atattgtttc
     7081 ttgttaaatc agcactttgt cttaatttaa acatattagt tagatacctt ttattttatc
     7141 taaaagctct tttaaaagtt cgtaaaaccc taagagcttg atttttgcga aataatagat
     7201 agaaataaat aatggaatac atccaagaac aagggcagaa actgaaaaga aatgcccttg
     7261 aggaagaata aaaattgcta tgccagctaa tatcagaaat cctaaaagaa atatatatgc
     7321 ttttaaatta tcactcattt tgcattacct cctctaataa acaagtacta taaagagata
     7381 gaggctgata gaatagcatg gtctggaaag ccgactcggc tattataatc agcatttttt
     7441 aagaattccc aagaataatt ttcatttgat ataggaatgt ttgcaaaaat atggtctaat
     7501 ttacaatatt tccaagaggt ttcctcagag ggagtatgta cggttaggcc tgctttattc
     7561 atttcagact taagcaatgg ataagagtaa aactccctag ctttgccctg ataggaatga
     7621 atatcgtcat tctgttggaa atatccatta ttaaagtcac ccagcacaat tgtattttca
     7681 tgtgttgcgg gtaaatttga gattagtttg tctagttgcg attttcgatg tttgaaatct
     7741 tgaaaaatgt tttctccacc gaccttgata cgaactccaa taatgtttaa ttcttgtcct
     7801 tcaattgtca ctctaacgtg taaaaagttt ggattattat catcattatc gatagtaatg
     7861 acttggcaat cattaactaa atcattcttt attgcaataa ggatttgatt tccaaaatca
     7921 atagtacgca catcttcaaa aattttgtat cccatatcct gtaatttagt acagaataaa
     7981 ctaggattat ctgtttttac atattctgtc aagcagacga tttctgaatt ttgtttagct
     8041 aattcatgta caatcatttc aggaatttgt tttccttgtc ctgaacgttg attgatattc
     8101 caagtggatg ctttaatttt tttcatatat aaacctttct atgttctgct ttactaacgt
     8161 aaagaagatt tattagatga ttgtttgcaa taacaaggta aacaagattt cctgttctgg
     8221 tttcatactc atttactagc tctctataat gtgctttatc agtgtctatt tttcccattg
     8281 attagtgaga ctagggctga gtgcaaaaac ggtatcaaga gtatctaatc tatctcgtgc
     8341 ttcttgatat tgttcagttt ttaatgtatt catcattttg tcctctcttt aatgttaatt
     8401 gagggagcaa atgctcctgt gtgatgtatg agtgaaatga ggaagtgcta gaagttgtat
     8461 ccatcataga tttctccaag ttctgtaaat ataagaatcc tcctttttgt atagtatatt
     8521 tgtgggatat tcccctatgt ttggtattat actacagtta aataaaaaaa tcaacaacaa
     8581 agatgcaata tttgaaaaaa atctctccat atgataaaat ttaatgtata gcaatggtag
     8641 gtaatgttag gagaaacaat ggaaactaga aatgaaaaat ttagaagatt atcagaagct
     8701 agaatgacta aggttttttc aattttaaat atattgagaa atcaaagtga caaatcgaaa
     8761 tacacttttt caaaatcaga cattgaggag ctatttggag cgttagaaca aaaaggtgaa
     8821 gaaataaaag agtttttcac tagccctatt acgataaaaa caatcaatct aaaaaaatct
     8881 tttcattatt ctatggttga tacaagtaat gataaggaag tagcttttaa gaaattatca
     8941 actgcaaggg tagaaaaaat tttttcacta atgaatttac ttgcaaatct tagcaataaa
     9001 tcgaattata attatagtga ttgggaagtg gaagaattgt tttcagctta tgatgaagaa
     9061 gtaagaaaat gcaaagtatt tttcgaagaa aagagaacag tatttaaata tagtgaataa
     9121 gtcaggaata ctaaagtgtt actaaaaata aaaaaactat cgtttttgtg atagaggtaa
     9181 ctttttgaaa aggctatttg actggcttta tatacttatg aaatgttaag agcccaactc
     9241 aaaatccagt gtccgcaagg acgtgccggt tcgaccccgg ccgccggtat agtatagtgt
     9301 taggaacgtt gttattcttc gttccttttt tatattattt ttggtataat tatagttatt
     9361 caaattttat ttagattaag aaagtgtagg ggagtatgtc ttgttctatc gatttattaa
     9421 aacatcggta tttgaaaaat attaaagaaa atcctgaatt gtttgtcgga attgagttgg
     9481 agtatcctgt tgcaagttta gaaggggatg ctacagatgt tgaagttata aaggatctat
     9541 ttcattattt agtttctact ttggatctca ccgtagcaaa ggtagatgat tttggcaatc
     9601 tgatccagtt agtagatccg ataagtcagg atgctatttt atttgaagtt tcctatacaa
     9661 cgattgagtt tgcatttggt aaggctgaaa cgattcaaga ggtcgaaaat cgtttcaata
     9721 attatatgaa tgtaattcag agaaagttag ctgaatcaaa tcatgctatt gttggctgtg
     9781 gtatccatcc caactgggat aaaaatgaga attgtccagt ggcttatcca cgctatcaga
     9841 tgttgatgga ttatttgaat ttgagtagaa atattattaa atcagattta catcatttcc
     9901 ctgaatatgg tacttttatc tgtgggagcc aggttcagct ggatatttca aaaaccaact
     9961 acttacgggt gattaatgct tttactcaaa ttgaagcggc taaggcttat ttatttgcaa
    10021 actctgagtt ttcgggtgcg gattgggata cgaaaatttc aagggatatt ttctgggaag
    10081 aatctatgca tggtatctat ccagagaatg ttggggtcaa tgctagactc cttaatgatg
    10141 aagctgattt ttttgactat ctaaatcatt ctgcgatttt tactgcggaa cgtgatgggc
    10201 agacctatta tttttatcct attcaggctg gggactattt ggctacgcct gaaatccaag
    10261 catttgctct gaatggggat gaggttatta tttcccccca agagaaggat tttgaaactc
    10321 atcgtagtta ccagtaccaa gacttaacga ctcgaggaac agttgagttt cgtagtgtgt
    10381 gtacacagcc acttgatagg acttttgctt ctgcagcttt tcacttggga ttattggtta
    10441 atttagacaa gttagaagct tacttagaaa cagcaccttt ctttaaagta tttggttatg
    10501 attacaagtt tttaaggaga caattttcta agaaaaatct tacagatgag gaagaaacta
    10561 cgattattga attttccaaa gacttactcc tactagctga ggagggacta gtggtgagaa
    10621 ataaggaaga aatgacctat ttacagcctt tgagagaaga attgagccta taatttctct
    10681 tataaaggga gaattttctg aaaaatcatg atataatgga cgagactata gataaaggat
    10741 agagagtaat gacattagtt tatcaatcaa cgcgtgatgc caacaataca gtaactgcca
    10801 gccaagcaat tttgcaaggt ttggcgacgg acggcggttt gtttacaccg gttacttatc
    10861 caaaggtaga tttggacttt gacaaattga aagatgcttc ttatcaggaa gttgctaagc
    10921 tagttttgtc agcattttta gatgacttta cagctgagga gttggactac tgtatcaaca
    10981 atgcctacga tagcaaattt gatactccag ctattgcacc attagtgaaa ttagatgggc
    11041 aatacaattt ggaacttttc catggttcaa cgattgcctt taaggatatg gccttgtcta
    11101 ttttgccata ctttatgacg actgctgcta agaaacatgg tttggagaac aagattgtta
    11161 tcttgacagc gacatctggt gacacgggga aagctgctat ggcggggttt gcggatgtgc
    11221 ctggtactga gattatcgtc ttttatccaa aggatggtgt cagcaagatt caagagttac
    11281 aaatgaccac tcaaactggc gacaatactc atgttattgc tattgatggt aactttgacg
    11341 atgcgcaaac aaatgtgaag cacatgttta acgacgtggc tctttgtgaa aaattgacta
    11401 ccaacaagtt gcaattttca tcagctaact ctatgaacat tggtcgtctg gtgccacaga
    11461 ttgtttatta tgtttatgcc tatgctcagt tggtcaagac tggtgagatc gtggctggtg
    11521 ataagattaa cttcacagta ccaacaggaa actttggaaa tatcttggct gccttttatg
    11581 ccaaacaaat tggtttgcca gttggtaaat taatctgtgc ttcaaatgac aataatgtct
    11641 tgacagactt ctttaaaaca cgtgtctatg acaaaaaacg tgagtttaag gtaacaacca
    11701 gcccatctat ggatatcttg gtatcttcaa acttggagcg cttgattttc catcttttgg
    11761 gaaataatgc tgaaaagaca gctgaactta tgaatgcctt gaacacgcaa ggacaatata
    11821 agttgacaga ctttgatgca gagattttgg acctctttgc agctgaatat gcgactgagg
    11881 aagaaacggc agcagagatc aagcgtgttt gtgagttaga ttcttatatc gaggaccctc
    11941 atacagctgt tgcttcagca gtttataaaa aataccaatc ggccactgga gatgtaacta
    12001 agacagtgat tgcttcaaca gctagtccat acaagttccc agtagttgca gtagaagctg
    12061 taactggaaa agcaggttta acagactttg aagccttggc tcaattacat gaaatctcag
    12121 gcgttgcagt gccaccagca gttgatgggc ttgaaatagc tcctgttcgt cacaagacaa
    12181 ctgtagcggc tgctgatatg caagcagcgg ttgaggctta tttaggactt taagatagag
    12241 ggagtaaact cggttgggaa accaactgag tttcttttca tcaggaggag agattgttta
    12301 agaaaaataa agacattctt aatattgcat tgccagctat gggtgaaaac tttttgcaga
    12361 tgctaatggg aatggtggac agttatttgg ttgctcattt aggattgata gctatttcag
    12421 gggtttcagt agctggtaat attatcacca tttatcaggc gattttcatc gctctgggag
    12481 ctgctatttc cagtgttatt tcaaaaagca tagggcagaa agaccagtcg aagttggcct
    12541 atcatgtgac tgaggcgttg aagattacct tactattaag tttcctttta ggatttttgt
    12601 ccatcttcgc tgggaaagag atgataggac ttttggggac ggagagggat gtagctgaga
    12661 gtggtggact gtatctatct ttggtaggcg gatcgattgt tctcttaggt ttaatgacta
    12721 gtctgggagc cttgattcgt gcaacgcata atccacgtct gcctctctat gttagttttt
    12781 tatccaatgc cttgaatatt cttttttcaa gtctagctat ttttgttctg gatatgggga
    12841 tagctggtgt tgcttggggg acaattgtgt ctcgtttggt tggtcttgtg attttgtggt
    12901 cacaattaaa actgccttat gagaagccaa cttttggttt agataaggaa ctgttgacct
    12961 tggctttacc agcagctgga gagcgactta tgatgagggc tggagatgta gtgatcattg
    13021 ccttggtcgt ttcttttggg acggaggcag ttgctgggaa tgcaatcgga gaagtcttga
    13081 cccagtttaa ctatatgcct gcctttggcg tcgctacggc aacggtcatg ctgttggccc
    13141 gagcagttgg agaggatgat tggaaaagag ttgctagttt gagtaaacaa accttttggc
    13201 tttctctgtt cctcatgttg cccctgtcct ttagtatata tgtcttgggt gtaccattaa
    13261 ctcatctcta tacgactgat tctctagcgg tggaggctag tgttctagtg acactgtttt
    13321 cactacttgg gacccctatg acgacaggaa cagtcatcta tacggcagtc tggcagggat
    13381 taggaaatgc acgcctccct ttttatgcga caagtatagg catgtggtgt atccgcattg
    13441 ggacaggata tctgatgggg attgtgcttg gttggggctt gcctggtatt tgggcagggt
    13501 ctctcttgga taatggtttt cgctggttat ttctacgcta tcgttaccag cgctatatga
    13561 gcttgaaagg ataggaaatg caaaaaacag cttttatttg ggatttagac gggactttat
    13621 tggactctta cgaagcgatt ttatcaggga ttgaggagac ttttgctcag ttttctattc
    13681 cttatgataa ggagaaggtg agagagttta tcttcaagta ttcggtgcaa aatttgcttg
    13741 tgcgggtggc agaagataga aatctggatg ttgaggtgct aaatcaggtg cgtgcccaga
    13801 gtctggctga gaagaatgct caggtagttt tgatgccagg tgcgcgtgag gtgctagctt
    13861 gggcagacga atcaggaatt cagcagttta tatatactca taaggggaac aacgctttta
    13921 ccattctcaa ggacttgggg gtggaatcct attttacaga gattttaacc agtcagagtg
    13981 gctttgtgcg gaagccaagt ccagaagcgg ctacctatct gctagataag tatcagttga
    14041 attctgataa tacttattat ataggggatc ggactctgga tgtggaattt gcccagaata
    14101 gtgggattca aagtatcaac tttttagagt ctacttatga agggaatcac aggattcaag
    14161 cgttagcaga tatttcccgt atttttgaga ctaagtgata aaaagattgt gtcagttttg
    14221 tgacagagac ctaacaaact atttcaagta acctagtttg ttacaaggag tagacagttc
    14281 tgttaaatag gcccgagagg gctttttttc tacatttttt gtgttatgat agacaggtac
    14341 tcatttgaaa ggaatttgaa agaatgaaga aaagaatgtt attagcgtca acagtagcct
    14401 tgtcatttgc cccagtattg gcaactcaag cagaagaagt tctttggact gcacgtagtg
    14461 ttgagcaaat ccaaaacgat ttgactaaaa cggacaacaa aacaagttat accgtacagt
    14521 atggtgatac tttgagcacc attgcagaag ccttgggtgt agatgtcaca gtgcttgcga
    14581 atctgaacaa aatcactaat atggacttga ttttcccaga aactgttttg acaacgactg
    14641 tcaatgaagc agaagaagta acagaagttg aaatccaaac acctcaagca gactctagtg
    14701 aagaagtgac aactgcgaca gcagatttga ccactaatca agtgaccgtt gatgatcaaa
    14761 ctgttcaggt tgcagacctt tctcaaccga ttgcagaagc tccaaaagaa gtagcatcaa
    14821 gttcagaagt tacaaagaca gtgattgctt ctgaagaagt ggcaccatct acgggcactt
    14881 ctgtcccaga ggagcaaacg gccgaaacaa ctcgcccagt tgaagaagca actcctcagg
    14941 aaacgactcc agctgagaag caggaaacac aagcaagccc tcaagctgca tcagcagtgg
    15001 aagcaactac aacaagttca gaagcaaaag aagtagcatc atcaaatgga gctacagcag
    15061 cagtttctac ttatcaacca gaagaaacga aagtaatttc aacaacttac gaggcaccag
    15121 ctgcgcccga ttatgctgga cttgcagtag caaaatctga aaatgcaggt cttcaaccac
    15181 aaacagctgc ctttaaagaa gaaattgcta acttgtttgg cattacatcc tttagtggtt
    15241 atcgtccagg agacagtgga gatcacggaa aaggtttggc tatcgacttt atggtagcag
    15301 aacgttcaga attaggggat aagattgcgg aatatgctat tcaaaacatg gccagccgtg
    15361 gcattagtta catcatctgg aaacaacgtt tctatgctcc attcgatagc aaatatgggc
    15421 cagctaacac ttggaaccca atgccagacc gtggtagtgt gacagaaaat cactatgatc
    15481 acgttcacgt ttcaatgaat ggataaaccc gacttgataa catcattttg acgaatgaga
    15541 tctagctttc gtgatggaaa gcgattctcg ttcgtttttt ctttgtcata ctcttcgaaa
    15601 atctcttcaa accacgtcag ttttatatga aacctcaaag ctgtgctttg agcaacctgc
    15661 gactagcttc ctagtttgct ctttgatttt cattgagtat caatttgaat ggaaaatgga
    15721 aagttattat cttgtaataa tccaagcaac attcttgcaa tctattttac tttatatcac
    15781 aattgattgg tcaactattg ataagtcaat ggataggagg aagaaatgat agagattcaa
    15841 gatttactgt atcaactccg cttgtctgag caagcgagta cgcaattgtt tgaaaaaggc
    15901 ttgggattag tttgacacgg tatcagattt tactgttttt gctggagcat tctccttgta
    15961 accaaatggc ggttcaggag cgtttgaaaa ttgatcaggc tgctttgaca cggcatttca
    16021 agattttgga aacggaaggt ttggtggagc gtcatcgtaa tcctgaaaat cagcgggaag
    16081 tgttggtaga ggctgcgaag tatgccaagg agcagttagt ggtgaatccc cctctgcaac
    16141 atatcaaggt taaggaagag atggaaagta tcttaacaga gtttgagaga acagaactca
    16201 gccgtttatt aaataaattg gttttgggta ttgaaaatat agaaatttaa ggagaaatag
    16261 atgtcaatta ttttaacaac gatcgttgct ttggagcatt tttatatttt ttatttggaa
    16321 agtattgcca cgcaatcaga tgcgactagt cgtgtattta atatggaaaa ggaagaattg
    16381 gctcatccgt cagtaagttc attgttcaaa aatcaaggaa tttataaggc tctgctagga
    16441 gtctttctct tgtatgtcat ttatttctca cagaatttag aaattgtgac tatttttgtc
    16501 ttatttgtga ttggtgctgc gacttacggc tctttaacag cggataaaaa attattttga
    16561 agcaaggtgg atcagctatt ttggccttga ttagtatttt actctttaaa tacacttgaa
    16621 ggttgattct aatctcgcta atccttttta atccagaata agggaaatat gttatacttg
    16681 tttttaagaa aaaagtctca ttgaattggt tttgaggagt tagaaatgaa agtattagtg
    16741 acaggttttg agcccttttg aggccattaa aggtttacca gctgaaatcc atggtgctga
    16801 ggtccgttag ctagaggtgc cgacagtttt tcacaaatct gctcaagtat tggaagaaga
    16861 gatgaatcgt tatcaacctg actttgtcct ttgtattggg caagctggtg gaagaactag
    16921 tttgacacct gaacgagtgg ccattaatca agacgatgca cgcatttctg ataacgaaga
    16981 taatcaaccg attgaccgtc ccattcgccc agatggtgct tcggcctact ttagtagttt
    17041 gccgattaaa gcgatggttc aagctataaa aaagagggct taccggcctc tgtttccaat
    17101 acggcaggga cttttgtctg cagccatttg atgtatcagg ctctctattt ggtagaaaag
    17161 aaatttccat atgttaaggc aggttttatg catattcctt atatgatgga acaggtggtg
    17221 aacagacaga ctattccagc tatgagttta gtggatattc ggcgagggat agaagcagca
    17281 atcggcgcta tgatagaaca tggagatcag gaactcaagt tggtaggcgg agaaactcat
    17341 tgatagaaaa aagcttgagt ggaaaaacct tcaagctttt ggacgttttc gagccaatac
    17401 tgctcggtaa aacataattt tagtgcattg gatataaggt aggagtgaaa aactagcaat
    17461 gccaaaggta atccaattga ggaagtacca aggaagaagc tgtaaatcta ggacaaagcg
    17521 ctggaacttg tagcccttca taaaggaacg gctagttttt aggattcgtc ttggtgggac
    17581 ctgtcctagg tctagactat aacagagaag aaattccacc tgtgaatagg cataatactg
    17641 tggaatatag aggatatttc ctacaatgat caagatgaga cttgcaagaa agtagagtcc
    17701 aaagaccatg aggaaacgct cggtttcaac tgatgagaga tctagatttg gaaactcagg
    17761 atgtagggtg acgaattttt tggctaaaaa gctactataa aagaggaggt aaatcccaag
    17821 taaattaggg atactccata aaaagagata gaaacgtttg agaagtaggg tcaaaaaggt
    17881 ttgagaaaag cgctcctcat caaagagagc taggctgttt tttacagatg gctccgtttt
    17941 agaatctttc atgagtgtca gtgttgcata gacggaactg gtcaaaagaa tagtcccgat
    18001 aaaggagact agtagaggaa agaggtaggt ttgaagtatt tggccaagta tgctgaaaaa
    18061 tggctgttct aaaacagtcc cgtggatccg agataaggga ttaagaaaac tagataagat
    18121 gaccagcata ctgggaagga tatagaggag aaagagacgg ggggtgtcag cctgaaaatg
    18181 ttttgactcc tgacgaattg tttttaaatc aatttttgga tagttcattc tcttattata
    18241 ccatagttct tatacatagt tcgtgacagt tcctactttt tttgataaaa tcatacagtg
    18301 tgtccttggg cacactgtat gaactgggac tgtctttccc agcttcggag gtaaaaaatg
    18361 tcagattcac caatcaaata tcgtttgatt aagaaagaaa aacacacagg agctcgtctg
    18421 ggagaaatca tcactcccca cggtaccttt ccgacaccta tgtttatgcc agttgggaca
    18481 caagccactg tcaaaactca gtcacctgaa gaattgaagg agatgggttc gggaattatc
    18541 ctatcaaaca cctatcatct ctggcttcgc cctggagatg aactcattgc acgcgctggt
    18601 ggtctccaca agttcatgaa ttgggaccag cctatcttga cagatagtgg tggttttcag
    18661 gtttattctt tagcagatag ccgtaatatc acagaagaag gagtaacctt taaaaatcat
    18721 ctaaatggtt ctaagatgtt cctatcccca gaaaaagcca tctctattca gaataatctg
    18781 ggttcagaca tcatgatgtc ctttgatgaa tgtcctcagt tttatcaacc ttatgactac
    18841 gttaagaaat cgatcgagcg taccagccgt tgggctgagc gtggtttgaa ggctcaccgt
    18901 cgtccacatg accaaggttt gtttggaatt gtgcaaggtg caggatttga agaccttcgc
    18961 cgccaatcag ctcatgatct tgtcagcatg gatttctcag gctactctat cggtggtttg
    19021 gcagtgggag aaacccatga agagatgaat gcggtcttgg actttacaac tcaactgctg
    19081 cctgaaaata aacctcgtta tctgatgggt gtgggagcgc cagatagctt gatcgatggg
    19141 gtcattcgtg gggtggatat gtttgactgt gtcttaccga ctcgaattgc tcgtaacggg
    19201 acttgtatga ccagtcaagg acgtttggtt gtgaaaaatg cccagtttgc tgaggacttt
    19261 acgccactgg atcctgagtg tgactgctac acatgtaata actatacacg cgcttacctt
    19321 cgtcacctgc tcaaggctga tgaaaccttt ggtatccgct tgactagcta ccacaatctt
    19381 tacttcttgc ttaacctgat gaagcaagtg cgacaagcca tcatggatga caatctcttg
    19441 gaattccgtg agtattttgt ggaaaaatat ggctataata agtcaggacg taatttctaa
    19501 aatggaattg atataaaaaa atcctaagtt ttctcttagg atttttcttc tttttttgat
    19561 agaataaagt gtacaatgaa aggaagaata aactcgtatg cgcattaaat ggttttcctt
    19621 ggttaggatt acaggtttac ttttggtact cttgtatcac ttctttcaga cgatctttcc
    19681 tggaggattt ttcggggtag atgtcttttt cacattttca ggtttcctga ttacagctct
    19741 actcattgaa gaattttcta aaaaccatga gattgatttg ataggatttt ttagaagacg
    19801 cttttatcgg attgtgccac ctgtggtttt gatggtcttg gtgaccatgc cttttacttt
    19861 cttggttcgc caagactatg ttgctggaat tggtggccag attgcgagcg tcttaggctt
    19921 tatgaccaac ttctatgaac tcctaacagg tgggagttat gaatctcagt tcattcctca
    19981 tttgtttgtt cataattgga gtttggcagt tgaggttcac tactatattc tttggggatt
    20041 ggcagtttgg ttcttatcca aacaagctaa atcaaatggt cagttgaagg ggatagtctt
    20101 tctcttatct gctgttgcct tcttgatcag tttcttctcc atgtttattg gtagttttct
    20161 agtgacctct tattcctctg tttatttctc cagtttaact catgtctatc cattcttttt
    20221 gggaagtatg ttagcaacta ttgtaggtgt tcgtcagacg acttccctcg tcaagcagtt
    20281 ggataaaatc tgggatttac gaaagacttt ggtagttttt ggaggaggct ttggtttcct
    20341 agttcttttg actttctttg tcaaattcac ttatcttttt gcctatctta tcggcttctt
    20401 gcttgccagt cttgcagctc ttgccatgat tctggcggcg cgtgtcttac atgaaaagac
    20461 acatcatata caggagccga agattatcag ctttttagcg gatactagct atgcggttta
    20521 tcttttccat tggcctttct atatcatttt ctcacagttg acatcaaatc ttcttgctgt
    20581 attactgact ctgatttgtt cttatggctt tgccagtctg tcattctatg tattggaacc
    20641 ttggattgca ggcaagaaca cacctatttt acaaactctt cgtcccctgc cttatattca
    20701 cgcaattctt gtagcaggta caggaatctt gaccatcatt gtctgcacgg tgaccttgtt
    20761 ggcaccacaa gtgggagcgt ttgagacaga cttgactgtc aatggcttga agcaagctgc
    20821 aacaaatatt ggccagacca aggtgatggc agaacgggca gatgcaaaca gtttgggaat
    20881 tgctgatggc actatgttaa ttggtgactc agtggcttta agggcaaata cagcactaca
    20941 gacagctctt cctggagcac agattaacgc gcaggtcagc gtaacaacca agaccgcaaa
    21001 tgaaatcatg ctaaataata gccagaataa atttttacct aagacggtgg tcattgcgac
    21061 tggggtaaat aatcctgaga attacaagga tgactgggac agtatcgtga aaaatcttcc
    21121 taagggacac catatgattt tggtgactcc ttatgaggga gataagacaa aagagaccta
    21181 tgccatcgtt gagaaggctg ctgcctatat gagagaattg gcagagaaga caccttacat
    21241 tacgatagca gattggaatc aagttgcgaa agagcatcca gaaatttggg caggaacaga
    21301 ccaggttcat ttcgggagtg agagtagcac tatcgaagca ggagcaaaat tgtatgcaga
    21361 tacgattgcc acagctttgc agacagctca agacaagccg gttaaatcaa aataacttgt
    21421 attaaaaaag agaagagttg gagaaatcca gctcttttaa aatatctcca aaaaataggt
    21481 ctataccatt tacaaataaa aaagaaaggt ttataatgta attgacataa taaattgcag
    21541 aatcaatctt ttaaggaggt taacattatg cctaactata ttaaagcgga tcagtttttc
    21601 tacccacacg gagttcgtcg aggtggttac ttggaacttg tggacggcaa gtttgggaaa
    21661 catgtagagc agattcctga aggggctgag gtgattgact atacaggtta tagcattgcc
    21721 ccaggtcttg tggatactca tattcatgga tatgcaggtg tagatgtgat ggacaacaac
    21781 attgaaggta cattgcatac tatgagtgaa ggacttctta gtaccggtgt taccagtttc
    21841 ttacccacaa ctttaacagc cacttatgag caattgcttg cagtcactga aaatcttgga
    21901 aaccattata aagaagcaac aggtgctaag attcgtggga tttattatga aggtccatat
    21961 ttcacagaaa cttttaaggg ggcacaaaat ccaacttata tgagagaccc gggtgttgag
    22021 gagtttcatt cttggcaaaa agcggcaaat ggcttgctta ataaaattgc ccttgcacca
    22081 gaacgtgatg gggtggaaga ctttgttcgt acagttacgg gcgaaggtgt gacggttgct
    22141 cttggacatt caaacgcgac ttttgatgaa gccaaaaaag cagtcgatgc tggagcgagt
    22201 gtttgggtgc atgcctacaa tggaatgcgt gggttgactc accgtgaatt gggtatggtt
    22261 ggagccatgt accaattgcc acatacctat gcagagttga tctgtgatgg tcaccacgta
    22321 gatccaaagg cttgcgaaat tcttatcaaa caaaaaggaa cagaaaacat cgctcttatc
    22381 acagactgta tgacagctgg gggattggaa gacggagatt atatgttggg agaattccca
    22441 gttgtcgttg caaatggaac tgcacgcctc aaatcgacag gtaacttggc aggttctatc
    22501 ctcaaactca aagatggttt gaagaatgtg gtcgaatggg gaattgcgaa tccgcatgaa
    22561 gcagtcatga tggccagctt caacccagct aaatccgttc acatcgatga cgtctgtggc
    22621 caaatccgtg aaggctacga cgctgacttc atcgtattag ataaagattt ggaattggta
    22681 gcaacctacc tagatggcgt aaaacgttat caagcataag agagaaagca gaagttagag
    22741 actaacttct gcttttttat gcagggtact ttactggtaa ataaaaagtt aaaaaaatca
    22801 caaaaaaagc ttgaagaaac aaagaaaaag gcttacaatt gaactataaa tattacaaat
    22861 aaaaaaacgg aggagtgctt tatgaaagcc tatacttatg ttaaaccagg acttgcttct
    22921 tttgttgatg tagacaaacc agttattcgc aagccaacag acgctattgt gcgtattgta
    22981 aaaaccacta tttgtggaac agacctccat attatcaaag gggatgttcc tacttgccaa
    23041 agtggtacca ttcttggcca cgaagggatt gggattgttg aagaagttgg ggaaggagtt
    23101 tccaacttca aaaaaggtga caaggtcttg atttcttgcg tctgtgcctg tggtaaatgc
    23161 tactactgta aaaaaggaat ttatgctcac tgtgaagacg aagggggctg gattttcggt
    23221 cacttgattg atggtatgca ggctgaatat ctacgtgtcc ctcatgcaga taatactctt
    23281 taccatactc cagaagactt gtcagatgaa gctttggtta tgctgtcaga cattctgcct
    23341 actggatatg aaattggtgt cttaaaaggg aaagtagaac ctggttgcag cgtagccatt
    23401 attggttcag gtccagttgg attggctgct cttttaacag cccaattcta ttcaccagct
    23461 aaattgatta tggtagacct agacgataac cgcttggaaa ctgccctatc attcggtgcg
    23521 actcataagg ttaattcttc agaccctgaa aaagccatta aagaaattta tgatttgaca
    23581 gatggtcgtg gtgtggatgt cgctatcgaa gctgttggta ttcctgcaac atttgatttc
    23641 tgtcaaaaga ttatcggtgt agacggaacg gttgccaact gtggtgtgca tggtaaacca
    23701 gttgaattcg atttagataa actttggatt cgcaacatca atgtaacaac tggtttggta
    23761 tctacaaata cgactccaca attgttgaaa gcgcttgaaa gtcataagat tgaaccagaa
    23821 aaattggtaa ctcactattt caaactcagt gaaattgaaa aagcctacga agtcttcagt
    23881 aaggcagcag accaccatgc cattaaggtc attatcgaaa acgatatctc agaagcctaa
    23941 gtagtaaaaa tatttggctc tttgtcaact gtagtgggtt gaagtcagct aagctcgaga
    24001 aaggacaaaa ttcgtccttt ctttttgatg ttcagagcga taaaaatcct ttttttgaag
    24061 ttttcaaagt tccgaaatcc aaaggcgttt cgtttgataa gtttgatgag attattggtc
    24121 gcttctaatt ttgcgttgga ataaggtaat tgaagagcgt tgacgatttt ttctttgttc
    24181 tttagaaagg ttttaaagac agtctgaaaa ataggatgaa cctgcttcag attgtcctca
    24241 atgagtccga aaaatttctc agg
//
LOCUS       DAVAGB010000028        24104 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVAGB010000028 DAVAGB010000000
VERSION     DAVAGB010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24104
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.028"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(1..255)
                     /locus_tag="VQO19_001318"
                     /pseudo
     CDS             complement(1..255)
                     /locus_tag="VQO19_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(639..1835)
                     /gene="tuf"
                     /locus_tag="VQO19_001319"
     CDS             complement(639..1835)
                     /gene="tuf"
                     /locus_tag="VQO19_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET1349573.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2746..3615)
                     /locus_tag="VQO19_001320"
     CDS             complement(2746..3615)
                     /locus_tag="VQO19_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET1349574.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3839..4516)
                     /locus_tag="VQO19_001321"
     CDS             complement(3839..4516)
                     /locus_tag="VQO19_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET1349575.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPIPEP
                     TPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLASLVLGFF
                     KKKEDEK"
     gene            complement(4474..5553)
                     /locus_tag="VQO19_001322"
     CDS             complement(4474..5553)
                     /locus_tag="VQO19_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET1349576.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVDSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDIVEPSRTVVEKIIPKLNIPEEEKKKKTSELAE
                     LISENVKVCYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNVTDKKLSSMT
                     TTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANYYKEGSQEKL
                     AESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPANAYQKTVQQ
                     LTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5664..5918)
                     /locus_tag="VQO19_001323"
     CDS             complement(5664..5918)
                     /locus_tag="VQO19_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349577.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPIWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(6258..6791)
                     /locus_tag="VQO19_001324"
     CDS             complement(6258..6791)
                     /locus_tag="VQO19_001324"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET1349578.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKNLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(6778..6993)
                     /locus_tag="VQO19_001325"
     CDS             complement(6778..6993)
                     /locus_tag="VQO19_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET1349579.1"
                     /translation="MGKERCEQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCAVPSVWAALKQIKVTLKKDDEL"
     gene            complement(6960..7103)
                     /locus_tag="VQO19_001326"
     CDS             complement(6960..7103)
                     /locus_tag="VQO19_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HET1349580.1"
                     /translation="MAYSTDFKQRALDYIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            7337..9055
                     /locus_tag="VQO19_001327"
     CDS             7337..9055
                     /locus_tag="VQO19_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HET1349581.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNETAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            9166..9513
                     /locus_tag="VQO19_001328"
     CDS             9166..9513
                     /locus_tag="VQO19_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET1349582.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     ADTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(9791..10627)
                     /locus_tag="VQO19_001329"
     CDS             complement(9791..10627)
                     /locus_tag="VQO19_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET1349583.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10640..11269)
                     /locus_tag="VQO19_001330"
     CDS             complement(10640..11269)
                     /locus_tag="VQO19_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET1349584.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11279..11920)
                     /locus_tag="VQO19_001331"
     CDS             complement(11279..11920)
                     /locus_tag="VQO19_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET1349585.1"
                     /translation="MSYLFEILPSLLNGASTTVHVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(12066..13295)
                     /locus_tag="VQO19_001332"
     CDS             complement(12066..13295)
                     /locus_tag="VQO19_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HET1349586.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(13285..14451)
                     /locus_tag="VQO19_001333"
     CDS             complement(13285..14451)
                     /locus_tag="VQO19_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET1349587.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14595..15608
                     /locus_tag="VQO19_001334"
     CDS             14595..15608
                     /locus_tag="VQO19_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HET1349588.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(15653..16072)
                     /locus_tag="VQO19_001335"
     CDS             complement(15653..16072)
                     /locus_tag="VQO19_001335"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HET1349589.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(16083..17489)
                     /gene="atpD"
                     /locus_tag="VQO19_001336"
     CDS             complement(16083..17489)
                     /gene="atpD"
                     /locus_tag="VQO19_001336"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HET1349590.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17575..18453)
                     /locus_tag="VQO19_001337"
     CDS             complement(17575..18453)
                     /locus_tag="VQO19_001337"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HET1349591.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLIGRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(18469..19974)
                     /locus_tag="VQO19_001338"
     CDS             complement(18469..19974)
                     /locus_tag="VQO19_001338"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HET1349592.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHTFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(19989..20525)
                     /locus_tag="VQO19_001339"
     CDS             complement(19989..20525)
                     /locus_tag="VQO19_001339"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HET1349593.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20525..21019)
                     /gene="atpF"
                     /locus_tag="VQO19_001340"
     CDS             complement(20525..21019)
                     /gene="atpF"
                     /locus_tag="VQO19_001340"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HET1349594.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(21033..21749)
                     /gene="atpB"
                     /locus_tag="VQO19_001341"
     CDS             complement(21033..21749)
                     /gene="atpB"
                     /locus_tag="VQO19_001341"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HET1349595.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLPYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(21784..21984)
                     /locus_tag="VQO19_001342"
     CDS             complement(21784..21984)
                     /locus_tag="VQO19_001342"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HET1349596.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(22059..23066)
                     /locus_tag="VQO19_001343"
     CDS             complement(22059..23066)
                     /locus_tag="VQO19_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET1349597.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKAPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSVTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYAFWERGTNENHNRFIRR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRF
                     Q"
     gene            complement(23524..23922)
                     /locus_tag="VQO19_001344"
     CDS             complement(23524..23922)
                     /locus_tag="VQO19_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET1349598.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT         7140 a         5142 c         4379 g         7443 t
ORIGIN      
        1 cttcctcaac tgtcatatat gatggttacg accaccacgt gtttcttgaa ggagagagtc
       61 gagtccgaac tcctcatatt tttttacatt tcgccaaatc gttgtttgat tacagtctaa
      121 aagctctata atctctttat aagatttgcc catcagacga aatagaacga tttgaaggcg
      181 tttatgatat ttagctgtac gagagtcttt taaaagtgtt ttgatggttt ggatttcttc
      241 tttaattgat ttcatattac tattgtataa tgctttttga ttttagtcta gtattatact
      301 cttcgaaaat ctcttcaaac cgcgtcagct tcgccttgtc gtatagatgt tactgacttc
      361 gtcagttcta tctacaacct aaaaacagtg ttttgagcag tctgtaacta actttctata
      421 gtaaaatgaa ataagaacaa gacaaatcga tcaggacagt caaattgatt tctaacaatg
      481 ttttagaagt agatgtgtac tattctagtt tcaatctatt atagtttact ctttgatttt
      541 cattgagtat tagttcaata tctaaaaaaa gaaccttgcc aagcaagatt cttttagtgt
      601 ctgacttaaa taattgttct tctgggaact aaatcgaatt aagcttcgat ttctgtaacc
      661 atacctgaac caacagtacg tccaccctca cggatagaga atgtagtacc ttgttctacg
      721 gcgattgggt gaatcaactc aacgtcgatt gtcacgttat caccaggcat taccatttca
      781 gtacctgctg gaagttcgat tgaacctgta acgtcagtag tacggaagta gaattgtgga
      841 cggtagttgt tgaagaatgg agtgtgacgt ccaccttctt ctttagtaag gatgtagact
      901 tcacctttga atttagtgtg tgggttgatt gaacctggtt tagcgataac ttgtccacgt
      961 tcgatttcat cacgttgaac accacgaaga aggacaccta cgttatctcc agcaagacct
     1021 tcgtcaagtt gtttacggaa catttcaaca ccagtaacaa ctgctttttg agtttcttct
     1081 ttgataccaa cgatttcgat ttcgtcgttg actttaacga taccacggtc gatacgtcct
     1141 gaagcaactg taccacgtcc agtgattgag aatacgtcct cgactggaag aagcaatggt
     1201 ttgtcagtgt cacgttctgg ttctgggata tactcatcaa ctgtgttcat caattccata
     1261 acgatgtctt cgtatttaga gtcaccttca agagctttaa gtgctgaacc ttggataact
     1321 ggaagatcgt cacctgggaa gtcgtattct gacaataggt cacggatttc catttcaacc
     1381 aattcaagca attcttcgtc gtcaaccaag tcaactttgt tcatgaagac gataaggtgt
     1441 ttaacaccaa cctgacgtga aagaaggatg tgctcacgag tttgtggcat tggtccgtca
     1501 gttgaagcta ctacaaggat agctccgtcc atttgagcag caccagtgat catgttttta
     1561 acgtagtccg cgtgtcctgg agcgtcgatg tgagcgtagt gacgtttttc agtttcgtac
     1621 tcaacgtgcg cagtgttgat agtgataccg cgttcgcgtt cttctggagc agcatcgata
     1681 gacgcatagt ctttaggttg gttaactgat gaaggcaagc gacgtgccaa aacagttgtg
     1741 atagctgcag ttagggtagt tttaccgtgg tcaacgtgtc cgatagtacc aatgttaacg
     1801 tgtggtttac tacgatcgta tttttctttt gccatttgag taaaagcctc caataaaata
     1861 tattttatag atagacagta ggcaatacag tctaactttc cttactattt tatcaaattt
     1921 cagctaaatt gcaagtgttt tacaacgttt ttgtgaatta ttcttggtaa aaatttaact
     1981 aattaataga aagtactaaa tagacttatc cttcaaggag ttttcagcat tatccatcca
     2041 ctcacttgct gaaaatgtaa acagtctctg gtttatatag taaaatgaaa caagaatagg
     2101 gcaaatcgat caggacagtc aaatcgattt ctaacaatgt tttagaagta gatgtgtact
     2161 attctagttt caatctacta tacaacctca aaactgtgtt ttgaacaacc tgcggctagc
     2221 ttcttagttt gccctttgat tttcattgag tataaaattg cagataaaac gataacaatc
     2281 ataggactca gcagagtcaa tgtaggtcga agaatagccc ccctaatcgc ttattttata
     2341 gcaaaatgaa atagaaactg aacattttgt tgaggaaggt aaatcaattc ctcacaatgt
     2401 ttgagaaaga aggggggact attccaactt caatccacta taaagcagac ttacaagata
     2461 gggaacccat ctccgataat atatagtaga atgaaaactg cacaatttga ttggagaatt
     2521 caaaccaatt tctaacaatg ttttagaaac aagggtctat tatttcaact gcaacctact
     2581 atagcccatt gaagctggaa tagcccactg aaacttctaa accactgctg gagaggagtt
     2641 tgtttagagt ttctttcatt tccctaaaaa atcaaaaaga gagaaccagt ctgatcctct
     2701 cttacttata gatggtgctc actcaaatgt taaaggagct atttcttaga gataaaggaa
     2761 tttgaataca gctactgccg caattgctgc tgcgataggt gctactactg gtacccaaga
     2821 ataccaccat tttgaatcgc ctttatgctc accaagaact gattttggaa ggaaagcatg
     2881 aaggagacgt ggtcccaagt cacgggctgg gttcaaggca ggtcctgtag gtcctccaag
     2941 tgatgttacc aaagccataa cgaggaatcc aagtgccaag tgagccacag aaagtcctga
     3001 agcagtgtgt ggagccacct gtgctttaat agccaagtca gaaaaatcaa ctgtttgtcc
     3061 tgcttctatt gccttttgtt tcatgaattg aagcacttca gcaccaaaga agtttttagt
     3121 caaaccaaga gctgcaaaga acaaaacaaa tgaaccaaca aactcattaa tcaaaccatt
     3181 gacagttgct gcatagcgac tttcttttgt accatggtca atacttgaaa tagttgagaa
     3241 agttcccaag atgttatttg gtttttcagt tttcaagtag aatggacggt atgttgccac
     3301 aactaaggct tggccaaaga tagcccccaa gacttgcgcg ataatgtaag gtaccacttg
     3361 tgcccaaggg aaaagaccgc taactgcaag ccctagagtg aaagcagggt tgatgtgatt
     3421 cccagatacg ttaccaaaca tcaaggctgg gatcataacc cccataccat aaccaacagc
     3481 gatgacgatc cagccacttt ggtgaccttt cgtaccttta agttcaacgt tggcaactgc
     3541 accattccca agaatgatca aaatggcagt tcccaaaaat tcagtggcat acttcagtgc
     3601 ccatgtgaaa tccatttgct agattctcct taaaattttt tagatattcc ttattttatc
     3661 aatttttacc ctatttagca actgatttct ggaaatattt ttaaaaaaat aggattcata
     3721 gtttcccagt tcaacgtact tgtaagcgtt tttattcttc acgaaagacc tcgttctcaa
     3781 aaccaggaaa aaagcccaca tctgtgagct tttcctggtt cctagattct aaaatctatt
     3841 atttttcatc ttcttttttc ttgaagaatc ctaatactag actagctaac aaggtcatga
     3901 taccagcact agccaaggta gcattagctt ctgtacctgt gtttggcaat tcctctctct
     3961 tacctgtctc ataagtcgga acttctgggt ctggattcac tggagtttca gtttttggag
     4021 tacctggttc tggagttggc tctggtattg gagtctcttg atttggtagt tctgggtttg
     4081 gtgtcggaac acttggatgc tctggatttg gttgtgggat tggtttttct ggagtcggtt
     4141 cacctggagt acctggttcc tgaggacttg gaatttctgg tttttctgga gttggtttat
     4201 ctggtgttga taaacggtca taccttaccg ttatttcttt atcactagag tctgacgtaa
     4261 cttcttgtga ttcaactgtt ggaatatctg gatctttgta cttgtcaatc ttaccagata
     4321 taacctcgtc ccagtttcct gttgtccatt caccgtaggt tacaactccc gtgaccttgt
     4381 tctcagtttt tgtacggctt aaggttacag gttgaacaac atcttctttt acattttggt
     4441 tcgtaacttt atcaacgtaa tgaatgatac gcgttatagt cttcgtctca gtagaggttg
     4501 ctgttttggg aaccactgtt tcctcaacat tctcacggta gtaatagtca actgttgcac
     4561 cgtcttctgg tacgcatttg caggagttgc taccaaggtg tatgttgttt tccttgtgat
     4621 aactcggtct tctttgtcct cagttgttgt tttcccttca atagtttttg attctgtggt
     4681 atactcagaa cctatcgcta aatcagcttt tataacagac tctgccaact tctcttggct
     4741 accttcttta tagtaattgg ctgttactgt agcagtggtt ggcgcttcgc tttctctata
     4801 aactaaggtc actgttctac cttcgcttac aatattccca gttaaacttg cagaatttgt
     4861 atctgcttct ttaaaagtat aatattttcc gtcagtagta gtcatgctac tgagtttttt
     4921 atctgtgaca ttatagctgg taccaatcag ttgtttttta ttggtaatgt aagttccgtc
     4981 actttctttt tctccaattc cagtatcatt tttcaatgat agcaaacgcc cttgttcatc
     5041 aacatagcaa actttcacat tttctgagat tagttctgcc aattctgagg tttttttctt
     5101 tttctcttct tcgggaatat ttagttttgg aatgattttt tcaacaacgg ttcgtgatgg
     5161 ttccacaata tcttggatga ctgaaaagtc agctagaatt gggagattat actgaacacg
     5221 gtgactttga gtgtttactc ctactctttc attattctct gaaaatactt gtacggtata
     5281 agaaacaaca tcttttccta atagaacatc cccagtagag aaatagccgc cttttcctag
     5341 tttgctatct ccagagtcca cttctttcct aatcttatca gatagttttt taccagtcag
     5401 tacattcgtt cgcacaatcc ctttgtctac ccctacaaag tgggagaact ttttgaactc
     5461 ttcagaacca gatctagccc aaccattatt aagggcattt gcttttgtat ttgtattctc
     5521 tctcaaaggt ttggcgatta gaattatatt catcggcact tagagttgct gctatatctg
     5581 actcttgaat accaacttcc ttactaccat ttctagcggc agtatatgtg tatttatctg
     5641 tttctacttc tagctgatta tccttaacat gataggtaat tttctcctgg tataagagtc
     5701 ttcagtagtt tatatgctct gtcatcatct ttagctttag aagcagctga gtttagccaa
     5761 attggggtat taggagtatc tttatcagcc tgtttcaaga cattattcaa gtcatttgct
     5821 aacctattgg ttgtcctcac tgtgaaagtt ttcttccagt ctgaaccact tttattagac
     5881 ttagatatgc tcatgaaatc ctggtcaaca ttcaacacaa tatcgccttg ttttttagca
     5941 tcttccgttg cttctgcttc aaattgatca tggagttttt gttgctctgg tgtatagttt
     6001 ttttatttac acgatttaat gtactatttt ttattttagt attaagaact ccattaatac
     6061 gatttttaaa ttctgcttca aaaaatccct taatttgttg gtgcgcaagt tcaacattca
     6121 aacctttctt atacaagtct tcattctgaa cgatttcggc tacacggtga atggtttgat
     6181 cgtataccgt cttctcttaa ccagcagtat ccttagtttt aatgactact cgataggttc
     6241 ctttagaacc gttatagtca tctagtttta aaaaagcatt ccaaacattc aaaaatagtt
     6301 ggaacttccc ttaataaatc cgtcactttc tttttcaaga tagcccaagc ttgctcaata
     6361 ggattcaaat ccggtgaata aggtggtaga ggtaagaaaa agtgtttatc ttggatgcag
     6421 agttcatcca aaatgttctt gggatgaaaa ctagcattgc ccatgacaat aacatgaggt
     6481 gtcttcaaag caggtaggag ttgcgttttg aaccactcca caaagaaatc gcttgtcatg
     6541 cttttcttgt aaatcatggg agctataaac tctccgtcta cttgtcctgc aacaattgaa
     6601 gttcgctcaa aacgacgtcc gctaatcttt tcatagactt tctcccctct aggagcccct
     6661 gcataaggac gatagaggta gcggtcgatt cctgtttcgt caatatatac gattggtaaa
     6721 ttttttaggt tatccaaaat atcaagaaac tcagcgactt tctctggctc ttgttcctta
     6781 aagctcgtca tcttttttta aagtgacctt aatctgcttt aaagctgccc atactgaagg
     6841 aacagcacaa tcaaaatgtg ccgcaatttc ccgtaaaaaa gcatctggat gagcctctac
     6901 aaaggctttc aattcctcta aaggaatctt tcggtttttg acgactcgct ttttcctctc
     6961 tatgtgtcct tgttcacatc tttcttttcc cacgtgaaga gagttctgac gccaacacca
     7021 aaaaacttgg ctgcctcgac atggctgtgc ccctctttga tgtaatctaa tgctcgctgt
     7081 ttaaaatcag tactatatgc catagcttta ttataatatg cttgtttaaa actaagcaac
     7141 tatatcaatg ttttgttatt agaagactta ctttttttac tgaaatcgaa tttttcctaa
     7201 cctcaacatc atataacccc aaaattcaat ctgacctggt ttgaagagat gttcgaagca
     7261 gataaggttt tactaaaact aaaaaaaatg atataatcaa actgattaaa tgttttaaaa
     7321 ataaaggaga atttgaatgt cttaccaaga aaattaccag aaatgggttg attttgtgga
     7381 gcttcctgac taccttcgtc aagatttgga aaatatggac gaaaaaacta aggaagatgc
     7441 cttctataca aatcttgaat ttggtactgc aggtatgcgt ggcttggttg gtgctggtac
     7501 aaaccgtatc aacatctacg ttgttcgcca agctactgaa ggattggctc gtttgattga
     7561 gtcaaaaggt ggaaacgaga aagaacgcgg tgtagcaatt gcctacgata gccgtcactt
     7621 ctcacctgag tttgcctttg aatctgcggc agttcttgct aaacacggca tcaaatctta
     7681 cgtatttgaa agccttcgtc caactccaga actatcattt gcagttcgtc atctcaactg
     7741 tttcgcaggt atcatggtca cagccagcca caaccctgct ccatttaacg gttacaaggt
     7801 ttacggtgaa gacggtggac aaatgcctcc acacgatgcg gacgctttga ctacttatat
     7861 ccgtgcaatc gaaaacccat ttgcagttga agttgctgat gtggaaactg aaaaagcttc
     7921 tggcttgatt gaagttatcg gcgaagctgt tgacatagaa taccttaaag aggttaagga
     7981 cataaacatc aacccagcct tgattgaaga atttggtaaa gacatgaaga ttgtctacac
     8041 accacttcat ggtactggtg aaatgttggc tcgtcgtgct cttgcccaag caggatttga
     8101 ctctgttcaa gttgttgaag cgcaagcaac tgctgaccca gacttctcaa ctgtaacatc
     8161 tccaaaccca gaaagccaag cagcctttgc ccttgctgaa gaacttggtc gtcaagttgg
     8221 tgcagatgtt cttgtcgcaa ctgacccaga cgctgaccgt gttggtgttg aagttcttca
     8281 aaaagatggt agctacctca acctttcagg taaccaaatc ggtgctatca tggctaaata
     8341 catcttggaa gctcacaaaa acgctggaac tcttcctgaa aatgccgctc tctgcaaatc
     8401 tatcgtttca actgacttgg taacgaagat tgctgaaagc tacggcgcaa ctatgttcaa
     8461 cgtcttgaca ggtttcaaat ttatcgctga aaaaatccaa gaattcgaag aaaaacacaa
     8521 ccacacttac atgatgggat ttgaagaaag cttcggttac ttgattaaac catttgtacg
     8581 tgataaagat gccatccaag ccgttcttgt cgttgctgaa cttgctgcct actaccgttc
     8641 tcgtggtttg acacttgctg acggtatcga agaaatctat aaagaatatg gctactacgc
     8701 agaaaaaaca atctctgtta ctctttcagg tgtcgatggt gctgaacaaa tcaaagcgat
     8761 tatggctaaa ttccgcaaca atgctccaaa agaatggaac gaaacagcta tcactgtcgt
     8821 agaagacttc aaggcacaaa ctgctactgt tgctgacggt actgttacaa acttgacaac
     8881 tcctccaagt gatgtgttga aatacacact tgctgacggt tcatggattg ccgttcgccc
     8941 ttcaggtaca gaaccaaaaa tcaagttcta cattgcagtt gtaggggaaa ccaacgaaga
     9001 atcacaagct aagattgcta acatcgaagc agaaatcaat gcatttgtaa aataaagacc
     9061 tataaaagat gagaccaacc aacctcatct tttttcgtat caaatctaag caattttaga
     9121 aactttatgg catactagac ttatcaatga aagcgaggta atctcatgga acaattttta
     9181 gataacatca aagaccttga agtcactaca gttgtgcgtg cgcaagaagc tcttgataaa
     9241 aaagaaactg caaccttctt tatcggtcgc aaaacttgcc cttactgccg taaatttgca
     9301 gatacattgt caggtgtcgt agctgaaacc aaagctcaca tttacttcat caatagtgaa
     9361 gaaccaagcc aactcaatga tttgcaagca ttccgctcac gctatggaat cccaactgta
     9421 ccaggttttg ttcatattac agatggacaa atcaacgtcc gttgcgactc ttcaatgtca
     9481 gcacaagaaa tcaaagattt cgcaggattg taaaaaatca gctaacaagt cttaaaatca
     9541 caaaaacgca taatgtaagg tgcaaaaacc ttgatattat gcgttttatt gttcctaaaa
     9601 cagttacatc agcatttcat tacagaacat tttaattttg gaagtcaaat caatttttaa
     9661 caatgtttta gaaatcacag tgggctattc catattcaat tatccatatt caatcgctat
     9721 tatcgttttc ctagattaca aaaaaactac gttttgctaa tcaaaacgca gtttcagcca
     9781 ctattttatc ttactgtcct tcttttactt ctttggttgc tacatcttct ccaaaccatt
     9841 tttggctgat ttcttggaac ttgccgtcct tgtaaagact agaaaaagct tcatttatct
     9901 tcttaaccaa ggttgtatct tccttacggg ctccaaccgc aaaagcttct gtttctagtc
     9961 caactgtaaa gacattataa tcgtttaaaa caccttctgc ttctaaataa tagtttgcat
    10021 agacacggtc aatcaataga ccatcaattc gatcgttttt caaatcaatc aaggcttcat
    10081 taaaggtttg gtattgattc gcttccttat tagcgacaat attcttcaaa atttctggat
    10141 ttgcttcaaa gtccgcataa ccagatgaac cagcttgagc tcctaatgtc tttccagtca
    10201 tatcctttgc agtcgtgata ccagatgatt tcttcgtaac caatacctgc tcattcttca
    10261 tatatgagtt actgaaagcc accttttcac ggcgttcgtc tgtagcggaa tagccattcc
    10321 aaatcagatc aatcgttcct tttgtcaatt cagcttcttt caaatcccaa tcaatcggtt
    10381 gccaatttac cgtgattccg tatttttcaa aaacagctgt agctaaatca atatcaaatc
    10441 ctgcataaga accatctttc tgagcaaatc ccattggaac aaaagtacta tcaaatccaa
    10501 tagtaataga cttgttagac tggtactttg accaattatc tccactagtt tcgctagaat
    10561 ttttcccaca agctactaag aacaaagcag tcatcagact gactaataca agcatccatt
    10621 ttttcatcca tttttcctcc tatttaggtt ctactttcaa taatacatct gcgatatttt
    10681 cagcaaactg caaatcatgg gtaaccacaa tctgggtcat cccaagttcc ctattttgca
    10741 agattagctt ctccacttcc aaacgtaatt ctggatccag ggcagaagtt ggttcatcgt
    10801 agccaatgat ttctgggtca atcatcatag cacgcgccaa agccacccgc tgcttttgcc
    10861 caccagatag tgagaaagga taggcctctg cgtgtcctcc tagtcctaac tgttccaaga
    10921 gtccactcgc cttcttctca gcctcttcct gcttcattcc catggtcttc acaggcgata
    10981 aagtcaaatt ttccagaact gatagatgag gaaatagttg aaaatcttgg aagacaaatc
    11041 ccagtaggtt gcgcttctgc aattcatcta gctctaaagg ttgtccatta taaaagattt
    11101 gccctgaatc aatggtttca agacctgcaa gcatacgtaa aagagttgtc ttacctccac
    11161 cagaaggtcc aacgatagcc aggatttgct tttcaggaat acttagactg aaatcagaca
    11221 ggatttgttt gtctccaaag actttattga tatttcgtaa ttctaacata gctgccctct
    11281 atctataata actgtacttt ttctcaactt ttttggaaat aattgtcaca atcccaatta
    11341 aaatcaagta aatggctcct gccaagaaca taggaaccag actagcatcg cggttagcag
    11401 ctgttcgact agccaagata aggtctgaaa ttccgagagc atagaccaaa gaagtatcct
    11461 tgaccaaact cataacttca ttaaagacac taggaagaac gatcttggtc acttggggca
    11521 agataatata gcgcactctg tcaaaagggc taaacttcaa gaccttggca gcctcatact
    11581 gtcctcttgg aatagtgtca attcccccac ggaaaatttc tgcaaagtaa gctgcatagt
    11641 tgagaacaaa ggcaataata gctgcaggaa ggcggtctaa acgaatccca atacttggga
    11701 gcacataata gataaaaatc agttgcaaga gtaagggggt tcctcgcata acccagatgt
    11761 aaatgttaat cagataatgg aggggcttcc aatggacttg caaggcaaag gcaatcaaaa
    11821 cgcccaaggg aatcgaaaat agcaagacca gtgcaaagac atgtacagtc gtgctcgcac
    11881 cattcagtaa actcggtaat atctcaaata aataagacat actgcacctc ctaaaagtaa
    11941 ttgttcctat tatagcatga ataaacaaga ttaccaagta tttttgtaaa aagattctac
    12001 catatacaaa taaaaaccgt agctatcaaa agagataaac tacagttcta tatgtttaaa
    12061 cattcttaca atctctcaaa cagttcttgc atttgcacat catctggaac cagttttaag
    12121 taagtgtgag catggacttt tgcttcttca aaatgtccca attcacgcaa gagatagata
    12181 tagtgttcca gaaattctgg attgtccttc aaatctcctg tcaactcttg ataatgctca
    12241 taagcagtat ccaaatcgtc catttcttga taagaacgag caatcatcca cttggtcaaa
    12301 agattttctg gctcctcact ctgcaagtct agaatatcct cataacgctc ctgctccaga
    12361 taaatagtgg ctaaacgaag caagatttct tctgtatcct cagcgtcttc ttttgcagta
    12421 aggagataat tttctgcacc actagcatca tgcaattcat aagaaaattg tgaagcagct
    12481 agcaagaggc gagtttcaaa gggatttttc tctaatcctt gcttagcgat acgcagggct
    12541 tcttgaactt gatgttcctt atgtaaagcc tgactgtacc catactcata gccttcaaag
    12601 tcaggagaaa tggtatcaag ctgcttaaag tagagggtgg ctttttgata ttcttcttga
    12661 tcaaaataaa gactggccaa ctcaaaagct gttaagtcat cgtattctaa ctccagggct
    12721 ttttctaaaa actcagtagc cgtttcaaat ttccctaact gagcataggc aaagccaatt
    12781 cgttgatagg tggaaatgcc cgtttgctca taaatcgagc gattatctaa ctgggcatag
    12841 gcttgaatag ccgcttggta attttccaac tcactatcca actctgccaa acccaatatc
    12901 aagagagaat cctctgagta ggtcaaggcc tccaataatt tctcacgtgc cacatctgtc
    12961 aaaccttcca gctggtaaag gtctgccttc agagccaaag acgagacata ccagtcactg
    13021 tcagcttgga tttcctcaag ataggtaaag gcttcttcta tttgaccatc ctcgctagca
    13081 attgcagcta gattaagatg aacctctgga aaatcctcta caattttcag gtaaatttcc
    13141 ttggcctgag gatagaaacc aatcccttca agataagttg ccaactcata cagaagatca
    13201 cttgaatcat tttctaaagc tttggcgaaa taatgctcag ccttagttaa atcttgctcc
    13261 tccaaagcct gtaacatctg ttgactattg ttcactcttg acttcctcac cctctaattc
    13321 atatagacca ctgactacct tataccattc gaaaatggct gaaatgacaa ccttagcaga
    13381 ggcataaacc ggaataccaa gtaaaactcc ccagatacca aacatagatc ctgaagttaa
    13441 caaaacaaag agaacattaa tagggtggat gtttaattga cttcccaaaa tcaatggaga
    13501 gacaaaacgg ccttcaatag tttgttctac gataaagaca atcactactt tcaaaagcat
    13561 gactggacca gcaatcaaac ccaatactag agcaggaagc atggctagaa agctaccaag
    13621 ataagggacc agatttaaaa taccagcagt aacccccagc gtaaccgcat agcgtagacc
    13681 aataatcttg aagaagatga taaacattac tgctacaata atagccactg tcacttgccc
    13741 tcgaacatag ttggacaact gttgattcac atctgataga acttgtccaa caggttcctt
    13801 caattttctt ggaatgaatt gggtcaaata gttacgcaag cctttcccat cacgcaagag
    13861 ataaaagagc atgaaaggaa cgataatcaa ggcaacaatc acttgagaag ccccgctaat
    13921 aaaggcactc acccagttga ctgcctgaga tgaaacctta cttgccaaaa ctgtagcctg
    13981 gctagaaaaa ttggtcaaaa cttgctctaa ttgaggtctg aaatcatctg gcagatgctg
    14041 ggctaccaat ccattaacaa tcctatctat atcttctaag taaacaggaa cgtttcttgc
    14101 aaaggtcaaa acctgacgtt gcagatttgg aatggcgact gccaagcccc aaatgataaa
    14161 gagagcgatg ataacaaaga caatagtgat agctataaca cgattaacct tatgcttctc
    14221 catccaatca acaataggat tcaacaaata atataacaaa ccagacaaaa tgactggcaa
    14281 catcacaact gctaaaaagt ctaaaacagg tgaaaataga aaactaatct tacttaaaat
    14341 aaaaagattc agtcccaata ataaggttac taaaaatacc gtaattgcct tgttatctaa
    14401 aaaccacttg aaaaaccaag ataggctaaa atgtttctct ttttgctcca taaatacttc
    14461 ctttctattg ttctctcatt ataccatttt tgaaacaaaa taactctttt ttaaagtgct
    14521 tacatctaat tggatatctt taatttactt gtttttgtga tataatagtc ttatctttac
    14581 acagaggtat agtaatgaaa gaaactgttt attttggaac ttatacacgt cgtacttctc
    14641 aagggattta caaggcagac tttgatacag aaactggtca gctttcaaat ctagaacttt
    14701 ttgcagctga gccaagtcca acctaccttg cctttgacca gcaccaacat ttatacactg
    14761 ttggtagcca agacgataag gggggaattg cagcctatca aactgacggg actgtgttaa
    14821 atcatgttgt tgaagaagga gctccccact gttatgttgc tgtcgatgaa aagcgtgatt
    14881 tggtttacgc agctaactat cacaagggac aagtccttgt ttataaacgc caggaagatg
    14941 gtagtcttct acttagtgat atggatcaac acagtggcca aggtccacat gaaaatcaag
    15001 cttcccccca tgttcactat acagatttaa cacctgacca ctatctagtg acctgcgact
    15061 tgggaactga ccaagtcatc acctatgacc tcgatcaaga aggaaaatta tctaagctct
    15121 atacctatca cagcaagcca ggagcaggct cacgccatat cattttccat aaccactata
    15181 aaatcgctta tctcatttgt gaactcaata gtactatcga agttttaatc tacgatggcg
    15241 ttggcgaatt tgaacgtatg caggtcattt caactttacc ggaagcttac gaaggcttta
    15301 atggaaccgc tgctattcat ctctctaaag acggtaaata cctctacgct tctaaccgtg
    15361 gccatgattc tatcgcagta tataccatcc ttgcggacgg tagcttagag ttattagaaa
    15421 tcgttccaac gcatggtcag actccacgtg attttgattt gacacccgac caaaaatttc
    15481 tcattgttgt ccatcaagac tctgacaatg caactgtctt taaacgtaat tgtgacaatg
    15541 gtcgtctagc agaactctcc aacgacttcc atgttcccga agcagtctgc atccgttttg
    15601 ctccttaaaa caccataaaa aatgaacttg gtattttcaa gttcattttt tcttatagtc
    15661 tatttccgac attaatacgg ttaatagcac gttgcaaagc aatcttagca cgacgttctt
    15721 ggtcaatcaa atgtttgtct tgtgcttctt caattgcacg ttctgcacga agtttggcac
    15781 gttctgcacg actgatatcg atatcacgag cacgttctgc agagtcagcg acgattgtga
    15841 tcatatcatt ggcaatttca ataacgccac cgtttactgc aatccagttc acgtgatctt
    15901 tatcatcgat acgttttacc tttacttcat caactgctaa aaccgcaatc atattttcat
    15961 gtcgtggcaa gatccccatc tcaccatcca gagttcgaac cgatacatag ctggcatggt
    16021 gatcatagac gagaccatct ggtgtcacga tctggacagt taactgagcc atagatcacc
    16081 tcttaaaatc ccattttttc agcttttgca atcacatctt cgatagaacc tacaccacgg
    16141 aaggcatctt ctggcaagtg gtcgtattta ccatcaagga tttccttaaa gccacgtaca
    16201 gtttcagcaa ctggaacata agaacctggc tgaccagtaa attgttccgc aacgttgaag
    16261 ttttgtgaca agaagaactg gatacgacgg gcgcgagcaa ccaaggtctt ttcttcatca
    16321 gaaagctcat ccataccaag gatagcaatg atatcttgca attcatggta acgttgaagg
    16381 acacgtttta cttcagcagc aactgcatag tgctcttctc caacgatttc aggtgccaag
    16441 gcacgtgagc ttgaagcaag tgggtcaacg gctgggtaga tacccaattg taccaactta
    16501 cgttccaagt ttgttgttga atccaagtga gcgaaggctg ttgctggcgc tgggtcagta
    16561 tagtcatccg ctggcacata gatagcctgg atagaggtta cagaaccctt cttggttgat
    16621 gtgatacgtt cttgcaattg acccatttcc gtagcaagtg ttggttggta accaacggct
    16681 gatggcatac gacccaaaag ggcagatact tctgaaccag cctgagtgaa acggaagata
    16741 ttatcgataa agagaagcac gtcttggcct tccacatcac ggaagtattc agcgattgtc
    16801 aaaccagtaa gggcaacacg catacgtgct cctggtggct cattcatctg accaaagacc
    16861 atggctgttt tctcgataac gcctgattct ttcatttccc agtaaaggtc attcccctca
    16921 cgagtacgtt ccccaacacc agtaaatact gaaataccac cgtgctcttg ggcaatgttg
    16981 tgaatcaatt cttggattaa gacggtttta ccaactccgg caccaccgaa aagtccaact
    17041 ttaccacctt taaggtaagg ggcaagaagg tcaataacct tgatccctgt ttcaaggatt
    17101 tcagaagagg tagacaactc atcaaaagtt ggagcttttt tatgaattgg ctgacgctct
    17161 gcgtcttctg taaaaggagc ttccaaatca atggtatctc ccaaaacgtt gaagacacgt
    17221 cccaaagttt ctttacctac tggtacagag attggacgac ctgtgtccaa tacttccatt
    17281 ccacgagtca acccatctgt tgattccatg gcgatagtac gaaccatacc atctcctaac
    17341 tccaaggcta cttcaaggac gatttttgtt tttctttcgt catttttgta gacgacaagt
    17401 gcattgttaa tctcaggaag tttttcccct gctgcaaaca aaacgtctac aacgggaccg
    17461 ataacctgag caattttacc tgaactcatc tccttctcct attctatata agatactgtc
    17521 ggttcctagc tcaactaggt cctaagttca ttttcatacg agctggacta gagcctattc
    17581 taaggcacta gcacctgcta cgatttctgt aatttcttgt gtaatcgccg cctgtctggc
    17641 acggttatac tgaattgtca aatcattgat gactttctta gcattatctg tcgctgtttg
    17701 catggctgtc atacccgcag cattctcagc tgtcttggca tcgataatgg caccgtaaat
    17761 catactttct gcaaactgag gcaacaactg ctccagaatt tcttctcggc tggtttccaa
    17821 ttcaaaagtc aagctgtact cttcatccgc ttcatttgga tccaagtcaa caatcggaag
    17881 catttgttcc acacgcattt gactggttag cgtattgaca tggtggttgt agcaaacata
    17941 aagctcatca aagagttcat tttggtacat ttcaacagtt tttgaaataa tcttacgaac
    18001 ttgatcaaag ctaggttggt ctgccaagcc acgtaattca taaagtggtt gaataccgcg
    18061 agccttaaag aaatcagctc ccatcccacc gatacagatc atttcaaaac ctttaccgtc
    18121 tgggtggtat tcttctttca actccataac agctttcaaa atagaggaat tataacctcc
    18181 aaccaaaccg cggtctgaag tgataacgat atagcctgtc ttcttcacag aacggccaat
    18241 caacatcgga ttagttgaag caccagctcc attaccatga aggatatctg tcaaaagttt
    18301 acgcactttc tgagcgtaaa cttggaagtt gcgagcagct tcttcagaac gacctagctt
    18361 agcagccgat accatttgca tggcattagt gatttgactc gtattttttg ttgaggcgat
    18421 ttttgtttta atatcattta gagatactgc catctgacac ctctattctt attggaagct
    18481 agattgattg agaaactctg taatcgcagc atccaagact gcttcttctg gcaagtcttt
    18541 tgtatcacga atggtttcca aaatctctgg atgttgagca tcaaagaagg tatggaactc
    18601 ttcctcgaaa cgaacaatat catctactgg aacagtatcc aagaaaccat gtgtcaaagc
    18661 ataaagaatg gttacttgtt tctcaacagg taatggtttg tgaacaggtt gtttcaagac
    18721 ctcaacggta cgacgtccac ggttcaactt agcctgtgtt gctgcgtcca agtcagaacc
    18781 aaacttagta aaggcttcca actcacggta tgaagcaagg tcgatacgaa gtgtaccagc
    18841 aaccttcttc atggctttga tttgtgcaga accacctaca cgagatacag atgaacccgc
    18901 atcgatggct ggacgaatac ctgcattgaa gaggccatcg ccaaggaaga tttgtccatc
    18961 agtgatagaa atcacgttgg ttgcgatata ggctgagata tctcctgctt gtgtctcgat
    19021 aaatggtagg gctgtaattg atccaccacc aagttcatca gaaactttag ctgagcgctc
    19081 aagcaaacgg ctgtggagat agaaaacatc ccctgggaag gcttcacgac ctggaggacg
    19141 acgaagcaag agcgatagtt cacgataagc taccgcttgt tttgatagat catcgtatac
    19201 aatcaaaaca tgcttacctt gatacataaa ttcttccgcc atagcaaccc cagtataagg
    19261 agctaggaag agcaatggag atggttgtga agcagaggct gtcacaacga ttgtgtagtc
    19321 caaggcaccg tactgacgaa gtgtttctac ttgcgtacga actgttgatt ctttttgtcc
    19381 aatcgcgacg tagatacaga tcatatcttg atctttttgg ttcaagattg tatcaatcgc
    19441 aatggttgtt ttccctgtct gacggtcacc gataatcaac tcacgttgac cacgaccaat
    19501 cggtacaagg gcgtcaatag ctttcaaacc agtttgcaat ggttctgaaa cagacttacg
    19561 ttgcataaca ccaggagctg gtgcttctac tggacgagtt ttatcagtgt ggatttctcc
    19621 aagaccgtca actggacgac caagcggatc cacaacacga ccaatcagac tttcacctac
    19681 agggacttcc atgattttcc ctgtacggcg gattgtatcg ccttcacgga tatctgtaaa
    19741 gtcacctagg atgataatac caacgtctgt tgactccaag ttttgagcca taccataaga
    19801 gccgttttca aaattcaaca actctccact catgacattt tcaaggccat gagcacgcgc
    19861 gataccgtcc ccgatatagg ttacaacacc tgtttcagtc acatcaaaat tgggtttgaa
    19921 attttcaatt tgttgcttaa ttaaagcgct gatttcttgt gcgttaattg ccaaaagaac
    19981 accactttct atttcaaatt ttctttaaca actttaagtt gttgtttaat actcacatca
    20041 attgtcttgt gattggcaaa aatgacaaaa ccaccaatga gactttcatc gatttgttct
    20101 tttacactcc ttactttcag agacattttt ttctcaatca aagggagcaa acgagtcttc
    20161 tgttcatcag ttagaggatg agcagacgta atcgtcactt caaatcgatt tgtttctttt
    20221 tcaagtcggt tcaagcaatc tacaagcaca tcataaaaaa gatttgctct gtgattgtag
    20281 gccagaacct ggataaagtt ttgtaataaa ggcgacacag aatcttggaa aaaagcaatt
    20341 gttttttcct tatccgactc gtctactgcc acttgtttta aaaaagaagg cagacctgtt
    20401 ttttcaacaa cttgcttgat ttgagtcaag tctgaaaaga tacggtcttc ttctcctttt
    20461 tcaagtacca attggacaaa aggcatgctg tatttttcaa ttacctttac tgttttcttg
    20521 tccattaagc ttctcctagc tgatcgatat actgatcaat gagtgcttta tgggcatgac
    20581 tgtcaaggtt ttgtgagatg attttaccag ctaagctgat ggtcaaatct gcgacctcac
    20641 ccttaacact ctgtaaagct tctactttat tttgagcaat ttcttgattg gctttttctt
    20701 ttaagtgtcc tgcttctagt ttagcatctg ctaagatatt agccttactt tgctcagctg
    20761 tttcctttgc attttcaatg attgtcttag cttctttacg gctaccagcc aattcatctt
    20821 cgcgtttttg agccaatact tctgcttttt gacgggcttc ttcagctctg tcaatatctg
    20881 aagcaatttt ttcagctctt tcttcgaaaa tgcctgtaat attagaccat gcaaattttt
    20941 taatcaagac tagcaaaaga ataaaagagc cagtgattaa aataaaatta ccaattaatt
    21001 cacctactgt tacgtgcatc agttactcct ttctattcct cttcaatatt aatcttattc
    21061 cctaaataca cagatgtcaa aagagtaaaa acataagctt ggatgcagga aataaagaca
    21121 gaaaatgcag tccaagccaa attagctcca aaggctactg gataccaata aatagcttgg
    21181 tgggaaagaa gaagtaacaa actcgtcatg acctctcctg caaagatatt cccaaaaatc
    21241 cgcaaagcca aagataagaa gtttgtaaat tcttccaaga tattcatcgg tatgacaaaa
    21301 acaggactca taaaagattt tatacttttt ttaaatccac gacgacgaac gctttctata
    21361 tgtgtcaaca aaatgacaag aaaagataag gttaagtcat acggtaaatt agcggttggc
    21421 gaactccacc agttagtccc atcgatcgtt tgaagctttg tcattaagcc aaggttattg
    21481 gcaatcacca tgaaaaggaa taaacaaagg aaaaagagtg agtaatcttt catgtagcgc
    21541 gaaccaatgt taggttctgt aaatccaata acaaagtcat agacatactc aagtacattt
    21601 tgctttcctt tgggtttcaa ggtcatattg cggcttgccc aataaataaa gacaaaaata
    21661 actcccacaa tcaacaaagt catggctaac atagtcagat tgaagataac aggaccaata
    21721 gagatgattg gattaatact ttcttccatc taaaatcctc ccttttcttc tcgttccatg
    21781 tatttatttg ataataaatg agaagacaag agttacaaag aaagttcctt caataaaggc
    21841 aacacctaaa aacatcaaac tacgaaactc agaaagcata tctggttggc gtgctactga
    21901 tttaaacagt ccattcatca ataaaccttc accgacagat acgcccatac aggcaataca
    21961 taagcctaaa aatgttaaat tcataacaaa ttctccttta aaataaaatt tacttactta
    22021 gtgtagtcct aaaatttaaa tttgtcaact tttaaccgct attggaagcg tttaataaaa
    22081 attatttcca ttttgctaaa tttcaagttc aagttagcca tccagaagtc ttctctgggt
    22141 gacttgtagt ccaagcattt tttaggatag ttgttaatcc acttttcgat gaatgcgact
    22201 tctttgggag tcattttctt ggttccctta ggtaaccatc tacgaatgaa cctgttgtga
    22261 ttctcattag ttcccctttc ccaaaaggca taggggtgcg cataataaat gtgctcctca
    22321 gaaaatacat caaacaagcg attgaattcc gttccattat ctgccgtgat ggaaagaatc
    22381 ttgtgttgtt ttaagatgag ttttagagcc tgattgacca cctcagcact tttatttgga
    22441 atcaatcgga tgatctgatg tctactcttt cgatccgtca agacaagcaa gcagtagttt
    22501 ttcgctctcg taagtagaac cgtatcaatc tcataatgcc cattctccaa gcgaagattg
    22561 atagcttcag accgctgttc gatggattga ccagcaggtt taaagttggt gctagcctgt
    22621 ttcttaagcg cttttccttt tctagggtaa agcagatcct gtttgcttaa ccccaatttt
    22681 ccatgatgaa tccaatagta aatggttgaa attcccacgt taaccccttt agccatcacc
    22741 atcatttcag gcgaaaattt ttggttatga tagtggagaa tcttttcctt tagttccttg
    22801 gtcacgcttg atttcttgac cgagcgcttg cgattgtttt cataagactg ttgagcatag
    22861 tcggcagaat aaacctcttt gaagcgccct tttccaagac attgtcggac tgtcccacgc
    22921 ttgatttcag tgtggatagt ttgaggagct tttccaagta gagaggcaat ttctctattt
    22981 gatttccctt cttttttcca tctttcgatt aagcgacggc tatcgattgt caaatgtttg
    23041 gcttttgtag tataattgtc ttgcatttct gtgcctttct tgtgtttgtg gttgaacaac
    23101 aagtataaca cagaggtgtt ttcttatgcc tacaagagtt ttcattattt ccattttctt
    23161 tcggatttca ctctattctg aaaaacttgt gtatatttac tgaagctagc aagtcttacc
    23221 tgtaaattta atgaaagcaa cacaaaatcc tagaggggaa tctcggatta atgtcaattt
    23281 aaaaagatag agagttttta gtttaaataa attgttttaa aatatcaaca acatcacttc
    23341 ttttcttaac ctgataagcc ttgattccta attttggagc tacgattata ttgtcctcaa
    23401 tatcgtctag aaagacacaa tttctaggtt ataactggta tttatcgata gttactcata
    23461 tacatcagta cacctccata cttatgtgcg agcctctctt tgtattatac ctccatactc
    23521 accttacaga ttcttttggt aataatatct ttgcctaatg tagagatagt cttgcaaaga
    23581 aaaaacttcc ttgtagccat gtttctgata aaagtccggt gcctggaact gataagtatt
    23641 gacaaaggca aaacaacaat ttcgattctt agcttcactt tctgcctgtt gcaatagttt
    23701 tgaaccgatt ccttgccctc gcagttcctc ttttacaaac aaatactcga tttctagcca
    23761 atttccaaaa gtctctgcta tcaaacccgc aaggagattg cccttttcat cttcgacata
    23821 aagattaagt ggctcacttt cagcctcttc cctttttgaa cggttataaa cacgaatcag
    23881 attccctatt tcttgcgatt tatgtgattc cttattttcc aatctaaagt ataatgaaat
    23941 gaaataaaac atgcgcaaat cgattaagga atttaatcta atttctaata atgtcttaga
    24001 aatcaaagtt tactatttta acttcaatgc actatacatc taatactcaa tgaaaatcaa
    24061 agagcaaact aggaaactag ccgcaggttg ctcaaaacac tgtt
//
LOCUS       DAVAGB010000029        24050 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVAGB010000029 DAVAGB010000000
VERSION     DAVAGB010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24050
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.029"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(81..395)
                     /gene="trxA"
                     /locus_tag="VQO19_001345"
     CDS             complement(81..395)
                     /gene="trxA"
                     /locus_tag="VQO19_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET1349599.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(412..633)
                     /locus_tag="VQO19_001346"
     CDS             complement(412..633)
                     /locus_tag="VQO19_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET1349600.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(732..1112)
                     /locus_tag="VQO19_001347"
     CDS             complement(732..1112)
                     /locus_tag="VQO19_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET1349601.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(1255..2208)
                     /locus_tag="VQO19_001348"
     CDS             complement(1255..2208)
                     /locus_tag="VQO19_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET1349602.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(2276..3484)
                     /gene="sstT"
                     /locus_tag="VQO19_001349"
                     /pseudo
     CDS             complement(2276..3484)
                     /gene="sstT"
                     /locus_tag="VQO19_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            3623..4183
                     /locus_tag="VQO19_001350"
     CDS             3623..4183
                     /locus_tag="VQO19_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HET1349603.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            4240..5148
                     /locus_tag="VQO19_001351"
     CDS             4240..5148
                     /locus_tag="VQO19_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET1349604.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            5100..5690
                     /locus_tag="VQO19_001352"
     CDS             5100..5690
                     /locus_tag="VQO19_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HET1349605.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            5693..6799
                     /gene="yqeH"
                     /locus_tag="VQO19_001353"
     CDS             5693..6799
                     /gene="yqeH"
                     /locus_tag="VQO19_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HET1349606.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKNKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            7013..7324
                     /gene="yhbY"
                     /locus_tag="VQO19_001354"
     CDS             7013..7324
                     /gene="yhbY"
                     /locus_tag="VQO19_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HET1349607.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            7376..8005
                     /locus_tag="VQO19_001355"
     CDS             7376..8005
                     /locus_tag="VQO19_001355"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HET1349608.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            8005..8598
                     /gene="yqeK"
                     /locus_tag="VQO19_001356"
     CDS             8005..8598
                     /gene="yqeK"
                     /locus_tag="VQO19_001356"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HET1349609.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDFDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            8599..9099
                     /locus_tag="VQO19_001357"
     CDS             8599..9099
                     /locus_tag="VQO19_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET1349610.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            9112..9465
                     /gene="rsfS"
                     /locus_tag="VQO19_001358"
     CDS             9112..9465
                     /gene="rsfS"
                     /locus_tag="VQO19_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HET1349611.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            9568..10314
                     /locus_tag="VQO19_001359"
     CDS             9568..10314
                     /locus_tag="VQO19_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET1349612.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKEKKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFSMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            10324..11421
                     /locus_tag="VQO19_001360"
     CDS             10324..11421
                     /locus_tag="VQO19_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET1349613.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILMQARESDLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKVDQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            11659..11889
                     /locus_tag="VQO19_001361"
     CDS             11659..11889
                     /locus_tag="VQO19_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HET1349614.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMDKIRAGH"
     gene            12158..13771
                     /locus_tag="VQO19_001362"
     CDS             12158..13771
                     /locus_tag="VQO19_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HET1349615.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREVDLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTKEIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     REVEGSHVEIGMELARKYKEHPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQNSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     REKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            13901..14527
                     /gene="gmk"
                     /locus_tag="VQO19_001363"
     CDS             13901..14527
                     /gene="gmk"
                     /locus_tag="VQO19_001363"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HET1349616.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            14552..14866
                     /locus_tag="VQO19_001364"
     CDS             14552..14866
                     /locus_tag="VQO19_001364"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HET1349617.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            14932..17328
                     /locus_tag="VQO19_001365"
     CDS             14932..17328
                     /locus_tag="VQO19_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HET1349618.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGKADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            17341..18276
                     /locus_tag="VQO19_001366"
     CDS             17341..18276
                     /locus_tag="VQO19_001366"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HET1349619.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            18269..19582
                     /gene="rsmB"
                     /locus_tag="VQO19_001367"
     CDS             18269..19582
                     /gene="rsmB"
                     /locus_tag="VQO19_001367"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HET1349620.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNALLRRILREGWPDISSIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            19597..20337
                     /locus_tag="VQO19_001368"
     CDS             19597..20337
                     /locus_tag="VQO19_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HET1349621.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIITSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            20334..22313
                     /gene="pknB"
                     /locus_tag="VQO19_001369"
     CDS             20334..22313
                     /gene="pknB"
                     /locus_tag="VQO19_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HET1349622.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            22428..23186
                     /locus_tag="VQO19_001370"
     CDS             22428..23186
                     /locus_tag="VQO19_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET1349623.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            23188..23637
                     /locus_tag="VQO19_001371"
     CDS             23188..23637
                     /locus_tag="VQO19_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET1349624.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            23699..24050
                     /locus_tag="VQO19_001372"
                     /pseudo
     CDS             23699..24050
                     /locus_tag="VQO19_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT         7162 a         4741 c         5612 g         6535 t
ORIGIN      
        1 ctatagtcta gcatattttt tgaaaaatgg caaagggcaa gaaaaaagag accaaagaaa
       61 gtacttggtc tctcgtttga ttagctcaat tcagcaatga tggccttgat ttgttctgct
      121 gtgtgaacac ctgcaacttg tttgacaact tggccgtctt ttttgaagag aagagttgga
      181 atagacatga ttccaaaagc acgagctgtg tttggatttt catcaacgtc cattttaacg
      241 attttcaaga catcttctga aagttcttca gacaatttgt ccaagattgg accttgcata
      301 cgacatggac cacaccaagt tgcccagaag tctactaaga ccaaaccgtc ttttgtttct
      361 tgttcgaatg ttgcatctgt aattgctttt gccattgtat ttctcctttt tttagttata
      421 ttggcttaaa tcttgtttca tgagatagaa gaagatatct ccataagtcc catggtagtc
      481 caaattatga cccttgtaag ttaatttttg gacagggtag tagtctgcga cgccgataag
      541 gcaagcttgt tgcgaacgtt caaagtcttc ataagactcg aaagtcacag ttctttcgtt
      601 cttgctggca tctatatagg taatttcaat catgtttaaa actcctttgt ttaatgctaa
      661 ctttatttta ctccttataa aagagaatgt caagaaaaat gattgcgcac gcaacttttt
      721 ttaaaatcat cttaaatcaa gaaatccaaa cctgcttcca agctttcttc gacagtcttt
      781 tgtagcgagg ccagtgtctt ttgcccatca tttgtcaggc agataaaact agagcgtcta
      841 tcttgatggc aacacatgcg actgagtaga ccgcaatttt tagcttccaa gcgagccacc
      901 atcctagaaa ctgcgctcgg gctcagatga agcttatctg gcaggtcaat ctggcgtaga
      961 gatttttctt cagccaagtc cagatagtag agcaggtaga actctttcaa ggtcagactt
     1021 tgctcgctct gttgggcaat ggtctcttcc aagagacttt caatttcttt ctgacgccga
     1081 ttgaagtcaa accatttttc caaataggtc atagtgtctc ctttcttttt agagtcataa
     1141 atagaagaaa gtccattaac gggcagtctc tgcgtcacaa gatgattgcg catgcaataa
     1201 ttatactact tttcaagaat gctggcaagc tctgtttttt agtggtttta ttttttactg
     1261 tctatatttt tggtaaaaat caacttttac ttggatgaag gttttggctt cacgtaggag
     1321 ttgaagaagg gtggcgcggg tttcaaactc ttctcttgtc ttgggcagac tgcggttccg
     1381 gaagacttcc agataacgtt caatttcatc tagcaaatca gaagcaggat tggtctggct
     1441 cagttgacct gcaatttttg aaaagagttg cgctaagatc aggctttcac tggcggcaag
     1501 gtgacaagtg ttaatctgtt gggccatgtt tctcaggata cgactttgtc gttgtctcat
     1561 ctcaaagtag tggatatggt agtcggtctg gtgaaagagg tggtcagagt gatccaaata
     1621 gaccagtctg agggcttctt tcaaaagcgt gtctaattct gctaccagct gtgctcggtt
     1681 gcgtccgtct cctctggata aatagtattt gaagcgctgg aggatatctt ttaacttttc
     1741 ttccaccagc gtgtggtagt gctggatttc ctcttctcgt gaaggcatat agagattaac
     1801 aagcaaggca aatcctgtac caatagcaaa gagaaggaat tcgttgacta ggaggtctgg
     1861 agaggttgac tcttgaacca agagatggct aaccaaaacc gtgcttggtg tgatgccaat
     1921 ttcccagccc atcttgtagg ctaaaggaac gtagaaggcc agatagaggc cgagactcca
     1981 gatatgaaat ccgctcaagt gaaaagctag aacaccgata gccagagcta gaagcataga
     2041 aaaaagacga ttgcgagcca gttttaaagt acttctacgc gtatcagata ggctcaagag
     2101 agcgataatt ccagccgaaa ctgctgacga aagattgaga aaataagcaa gcaggcaggc
     2161 aagacaggta gctaagatga gcttggtcgt acgttggcta atagacataa gaatttccta
     2221 ataagttaga ataaaagcgt aaaagacaag acatgagcag gcttgccttg atgagttatt
     2281 ttttacgggt tgctgcgtat tcggcaacgg cggtaaagag gacatctgta gaagagttaa
     2341 gggctgtttc acatgagtct tggatgacac caatcacaaa accaacccca acaacttgta
     2401 tggcaatatc gttagaaata ccgaaaaggc tacaagcaac tgggataaga aggagggaac
     2461 ctccggcaat acctgaagca ccacaggctg agatagctgc taccacactg aggacaaagg
     2521 ctgtggcaaa gtcaacagga attccaagag tgttaactgc agcaagggtc aaaaggttaa
     2581 tggtaatcgc tactccagcc atattgatag tagaaccgag tgggatagaa acagaatagg
     2641 tatctgggtt gagtccaagg tcatggcaga gtttcatgtt gacaggaatg ttagtcgcag
     2701 aactacgagt gaaaaaggct gtcacaccgc tgacacggag gcagttccaa actagagggt
     2761 aaggattgcg tctcataaag aagaaggcaa tcaaagggtt gaccacaggg gcaacaaaaa
     2821 gcatagtcgt tactaataga accaataaaa taccgtagtt ggcaaggctt ccgactccct
     2881 tgtcagaaat ggttttaaaa acaagaccaa ggattccaaa tggagccaga ttgatgatcc
     2941 attcgacaat tttagaagtc acgtcagcga tagtttttag caattcttta ctatttttac
     3001 tggcttctct catagcgatt ccaaaaatga ctgcccaaga taagattcta atatagttag
     3061 cagtaagcag ggcgttgact gggttgtcaa ccagtttgag caagaggttg ctgaggacct
     3121 gcccaatccc atctggtggt gcaatttcag tattggcact atttagggta atttcaatag
     3181 ggacgatgaa acttgctagt acagctacaa gagcagcggc gaaagtccct atcataggat
     3241 atacaagaaa acaacagttt tcatattgct atcttgtccc ttttgatgtt ggaaagggca
     3301 ttggcaacga gggcaaagac taggatagga gcaacagctt ttagacctcc aacgaataaa
     3361 tccccgagta gcccaatccc tgagagatta ggaagggtca gtcctaggat tccccacaaa
     3421 gcataccaat caagatacgc ttgacaaggc ttgccttatt ccaagcatga atgattcttt
     3481 tcataataat ctcctttttg tgtagtgatt atgattatag tataaatgat agacaaaatc
     3541 aagaattttc tgtctgtttt ttgaatattt atggagaatg agactgatga aaatatggta
     3601 taatgaaata aaggagtttt atatgcaaaa atttattcag gcttatattg aaaagctaga
     3661 tgtgacaacc attatcgaga atattctaac caaggtcatt tctcttttac tgcttttgat
     3721 tgtattttat attgctaaaa aaatgcttca taccatggtg cagagaattg tcaaaccttc
     3781 tctaaaaatg tctcgtcatg atgtcggacg ccaaaaaacc atctcacgtt tactagaaaa
     3841 tgtgtttaat tatacgctat atttcttttt actctactgc attttgtcga ttttaggttt
     3901 gccagtttct agtttgctgg ctggagctgg tattgctggg gtagcgattg gtatgggagc
     3961 ccaaggcttt ctgtctgatg tcatcaatgg ctttttcatc ctctttgaac gtcaactgga
     4021 tgtgggagat gaggtcgttc tgacaaatgg accgattact gtatcgggta aggttgtcag
     4081 tgtgggaatt cgtacgacac agcttcgtag cgaggagcaa gcccttcact ttgtccctaa
     4141 ccgaaatatc acagttgtta gcaatttctc acgcacagac tagacctgtt attttaagta
     4201 atttgtggta caatagaggg agtttaataa ggagaaaaga tggttttaga aaagcagttg
     4261 ggcaatggtt gtacctggat agacctagac ctaggaaagt tgaataaact agaagacctt
     4321 tctgaaattt acggtttgga caaggaaacc attgaatacg cactggatag aaacgagcgc
     4381 gcccacatgg attaccaccg tgaaagtggg acggttacct ttatctataa tgtcctagac
     4441 gtaaaaaagg acaaggccta ctatgagact tttcccatga cctttattgt cgagcatcgt
     4501 cgcctgatta ccattagtaa taccaagaac gcctatgtca ttgaacagat gactcgttat
     4561 ctggagagcc atgacacgct ttcgatttat aagtttctct ttgccagtct ggaaattatc
     4621 agcaatgcct actatcctgt cattgagcag atggacaaga gtagggatga ggtcaatgac
     4681 ctcttgcgcc agcgaactac caagaaaaac ctctttgccc tgtctgattt ggagactggt
     4741 atggtttatc tgacggcagc tgccaaacaa aatcggattt tgttagagca tattcaaggt
     4801 catgccttgt atcgtagttt tgatgagatt gagagagaac agtttgatga tgccatgatt
     4861 gaggctcatc agctggtatc catgacagac ctaatctctc agattttaca gcagctttca
     4921 gcctcttaca acaatattct aaacaataat ctgaatgaca atttgacaac cttgactatc
     4981 atttcagtct tgctagctgt tttggcagtc gtgacaggct ttttcggaat gaatgttccc
     5041 ttacctttaa cagatgagcc ccatgcttgg ctctatatca gtttggctag tgcaggtttg
     5101 tggattgttt tatccttgtt actaaggaaa attgcgaaaa aaagttaaga aaaggagcca
     5161 gaatggcgat tgaaaattat ataccagatt ttgctgtgga agcagtctat gatctgacag
     5221 tcccaagcct gcaggcgcag ggaatcaagg ctgttttggt cgatttggat aataccctca
     5281 ttgcttggaa caaccctgat ggaacgccag agatgaagca atggctacat gaccttcggg
     5341 acgcgggtat tggcattatc gtagtgtcaa ataacaccaa aaaacgcgtt caacgagcag
     5401 ttgagaaatt tgggattgat tacgtttact gggccttgaa gcccttcaca tttggtattg
     5461 accgtgctat gaaggaattc cactatgaca aaaaggaagt ggtcatggtt ggcgaccagc
     5521 tcatgacaga tatacgagca gcccaccgtg cagggattcg gtcaatttta gtcaaaccct
     5581 tggtccaaca tgactcaatc aaaacgcaga ttaaccgaac tcgtgagcgt cgtgttatga
     5641 gaaaaatcac tgaaaagtac ggaccgatta catataaaaa aggaatttaa ctatggaaga
     5701 aattctctgt attggttgtg gagcaaccat tcagacgaca gataaagctg gtcttggttt
     5761 taccccccag tcggcacttg aaaaaggttt ggagactggc gaagtctatt gccaacgctg
     5821 tttccgtctc cgccactaca atgaaatcac agatgtccag ttgacgaacg atgatttcct
     5881 caagctcttg cacgaggtgg gagacagtga tgccttagtg gtcaatgtca ttgatatctt
     5941 tgattttaat ggatctgtca tcccaggttt accacgtttc gtctcgggca atgatgtcct
     6001 cttggtagga aataaaaaag atatccttcc taagtcagtt aagtctggta agattagcca
     6061 gtggctcatg aaacgtgccc atgaagaagg tcttcgtcca gtcgatgtgg tcctaacttc
     6121 agcacaaaat aaacatgcca ttaaggaagt cattgacaag attgaacact accgtaaggg
     6181 ccgcgatgtc tatgtggtcg gtgtgaccaa cgttggaaaa tcaactctaa tcaatgctat
     6241 tatccaagaa atcacgggtg atcagaatgt catcactact tcacgcttcc caggtacaac
     6301 cttggacaaa atagagattc cgcttgacga cggatcttat atttacgata cgccgggaat
     6361 tatccaccgc caccagatgg ctcactactt gacggccaaa aacctcaagt atgtcagtcc
     6421 taaaaaggaa atcaagccta agacctatca gcttaatcct gagcaaaccc tatttttagg
     6481 tggtttggga cgctttgact ttatagcagg agaaaagcaa ggatttactg ctttctttga
     6541 taatgaactc aaacttcatc gtagcaagct tgaaggagct agtgctttct acgataagca
     6601 cctgggaact cttctgacac caccaaatag caaggaaaaa gaagatttcc caaggctagt
     6661 ccagcatgtc tttaccatta aaaataagac agacctagtc atctcaggcc taggttggat
     6721 tcgtgtaaca ggcatagcaa aagtcgccgt ctgggcacca gaaggcgtcg ccgtcgtcac
     6781 acgaaaagca attatttaaa acaaaatcgc tgagcgaaca aagtgagctc atatagcgat
     6841 agttattgcc gtggtgtgat tgccaatctg tagattggca aggggcacaa ttgagaccaa
     6901 ggctcaattg tgaggtcagg aaatccattt ttcaaagatg aaatctttgg aaaattagtt
     6961 ccgaccgtcc ctcaccacct aaaataacta tccaaaaaca aggaagaaaa ttatgtcatt
     7021 aacatcaaaa caacgtgcct tcctcaacag ccaggcacac accctcaaac ctatcatcca
     7081 aatcgggaaa aatggactca acgaccaaat caaaaccagc gtccgtcaag ctcttgatgc
     7141 gcgtgaatta atcaaggtta ctctcttaca aaacacagat gaaaacatcc acgaagtagc
     7201 tgaaattttg gaagaagaaa tcggtgtgga tacagtccaa aaaataggac gcatcttgat
     7261 tttgtttaaa caatctagca agaaagaaaa tcgcaagatt tctaagaaag tcaaagaaat
     7321 ctaagaccga aactccaaat aactgttttt atagagaaat aaaggggact agcctatgac
     7381 aatcgaacta ttgactccct ttaccaaggt agagttggag ccagaaatca aggagaaaaa
     7441 acgcaaacaa gttgggattt taggggggaa ttttaaccct gttcacaatg cccatctcat
     7501 tgttgcggat caagtacggc aacagttggg actggatcaa gttctgctca tgcctgaata
     7561 ccaacctcct cacgttgata aaaaggaaac catccctgaa caccatcgtc tcaagatgct
     7621 tgagttggca attgagggaa ttgacggcct agtcattgaa accattgagt tggagcgcaa
     7681 gggtatttcc tacacctacg acaccatgaa gattttgaca gagaagaatc cagatacgga
     7741 ttattacttt atcatcggcg ccgacatggt tgactatctg cctaagtggt accgaattga
     7801 tgaactggtt gacatggttc agtttgtggg ggttcagcgt ccacgctaca aggtagggac
     7861 ttcctatcca gttatctggg tggacgtacc gctcatggat atctcgtcca gcatggtgcg
     7921 ggacttcatt gcccaaggtc ggaaacccaa ctttctccta cctcagccag tgctagacta
     7981 catcgagaag gaggggctct actgatgtcc tatcaagact atatcaactg ctcccgtgag
     8041 gccttgttgg aaaaaatggc agagcttcta cctgagaaac gtctaaccca ttgtctaggt
     8101 gtggagcgtg ccgctatgga attagctcag cgctttggtg tagatgttga gaaagcaagt
     8161 ctagcaggtc ttcttcatga ctatgctaaa aagttgtcag atcaggaatt tctagacttg
     8221 attgaccgtt accagctaga tttcgacctc aaaaactggg gtaataatgt ctggcatggt
     8281 atggtcggaa tttacaaaat tcaggaagat ttggatttgc atgattcaga aatcctgcga
     8341 gccattgaag tccatacagt cggtgctggt caaatgacag acctagataa ggtcatctac
     8401 gtcgcagact atatcgagca caatcgagcc tttcctggag tagatgtggc gcgtgagatt
     8461 gcaagtctat cgctcaataa ggcggtggcc tacgaaacag ctcgtaccgt ggagtatcta
     8521 gctcatcagg gattccccat ctatccccaa acccttgaaa cctataacgc ctttgtgcac
     8581 tatttgaaag agaactaaat gaagacggct tttataatca ttgatgttca gaatgtttta
     8641 gtagaaactg ggttccagac aaaaagtcta ttgggaaaaa tttcttattt acaaaaccag
     8701 gctagaagca agaatattga aattatctat gttcaacata ttgagaactc tgaagctcaa
     8761 acatcagaag attggcagtt atctgcgctt ttaaatcgaa aacctgctga aaaggtcttt
     8821 cagaagaagt ataacagtat tttcaaagaa actggcttaa aagaatactt ggataagcag
     8881 gggattgaaa aattagtttt atgtggtatg cagacagaat attgtgtgga tacctctgtc
     8941 aaggttgcct ttgaatatgg ctatcagctt attgttccag aaggtgctgt cacaaccttt
     9001 gatggggatg acattccagc agaaacgatt aatgaatttt atgaggacat ttgggaggag
     9061 cgctttgcag atgtcctaga ttacaaacat attttctaaa aagaggatta aatgaacgaa
     9121 aaagaattac tagaactagt cgtgaaagcg gctgatgaga aacgtgcgga ggatatcctc
     9181 gcacttgatg tacaagattt gactagtgtg acggactact ttgtcatcac tagctcaatg
     9241 aatagccgtc agttggacgc tatcgcagct aatatccgtg aaaaagtagc tcaagcgggc
     9301 tttaaaggta gccatgtcga aggcgatgca gctggaggct gggtcttact ggacctcggt
     9361 gctgttgtcg tgcatatctt ttcagaagaa atgcgtgccc attataatct agagaagcta
     9421 tggcatgagg cgaattcagt agatatttca gaagctcttg cttagaagat gaactcagtt
     9481 gtagtcaact gggtttcttt gcttatttta gaaaaattga tagaaaggta aagggctagt
     9541 ggtgtttacc atggagctct tagtatcatg attatggcga cttatgaaac ctttgcggcg
     9601 gtctatgatg cggtcatgga cgatagttta tacgacaaat ggacaaattt ttctctgcgt
     9661 catttgccta agaccaagga gaaaaagaaa ctcttggaac tggcttgtgg gacaggaatt
     9721 caatcagtgc gcttctctca ggctggtttt gatgtgactg gacttgactt gagtgcggat
     9781 atgttgaaga ttgcggagaa gagagcaact tcagccaagc aaaagattgc ttttatagaa
     9841 ggtaatatgc taaatttgtc caaggcaggg aaatacgatt ttgtcacgtg ttattcggac
     9901 tctatctgct atatgcagga tgaggtggaa gtaggggacg tctttaagga cgtgtacaat
     9961 gcgctgaatg aagagggagt tttcatcttt gacgtgcact cgacctacca gacagatgaa
    10021 gtattccctg gctattccta ccatgaaaat gcggaagatt tttccatgct ttgggataca
    10081 tatgaggacg aagttcctca ctccatcgtg catgagctga ctttctttat caaggaggct
    10141 gacggttcct ttagtcgcca cgatgaagta catgaggaga ggacctatga gatcttgacc
    10201 tatgatatct tgctggaaca ggctggattc aagtccttca aactctatgc agactttgag
    10261 gataaggagc caacagaaac tagcacccgt tggttttttg tggcgcagaa gtaggagatt
    10321 agcatgacca tcacaggtat tatcgcggag ttcaatcctt ttcataatgg ccataaatac
    10381 ctgctggatc aggcagaggg actgaaaatt gttgccatgt cagggaattt catgcagcgt
    10441 ggagagcctg ctattgtgga taagtggaca agggcccaga tggcgctgga aaatggcgca
    10501 gacttggtag tggaattgcc ttttttagtc agtgttcagg cagctgattt ctttggtcaa
    10561 ggagctgtgg atatcttgga tcgcttgggc attgatagtc tagtttttgg gacagaggaa
    10621 gttcgagatt atcagaaaat cgctgactta tacacagaga aaggtgctga gatggagaaa
    10681 tttgtggaaa atctgcctga ttccctttcc tatccccaga aaacccaagc tatgtggaag
    10741 gaatttgctg gtcttgattt ttcaggtaat acccccaatc atgttcttgc tctggcctat
    10801 gcaaaggcgg ttgcaggacg aaatatcaag ctgcatccga ttcagcgtca gggggcaggt
    10861 taccattctg tgaataaaga tgtggacttt gcctcggcga cagccctccg tcaacatcag
    10921 aaggaccaag atttcttaga acgttttatg ccttctgttg ccctatttga gcaggccagt
    10981 aaggtgatct gggaagacta ttttcccttg ctccgctatc aaatcttgtc aaatcccgac
    11041 ctaaccacca tctatcaggt caatcaagaa atggctgtgc gcattaaaga agctattaaa
    11101 acagcccagt ctgtggaaga attggtcgag ttagtgacta ccaaacgtta caccaaggcg
    11161 cgtgtcagac gcctattgac ctatattttg atgcaggcta gagaaagtga cttgccagaa
    11221 gccattcatg tccttggatt tactgaaaaa ggtaggcaac atctcaagtc tttgaaaggt
    11281 caggtcagtc tagtcagccg aattggcaaa gaaccttggg atgctatgac tcaaaaggtt
    11341 gaccagattt accaactagg aaagccaagt atagcagagc aaaattttgg cagagtgccg
    11401 attagaatag aaacaaacta agtctaccga aaggtggact ttttgagatt ttttacgaat
    11461 aatactcttc gaaaatcaaa ttcaaatcgc gtcaacgtcg ccttgccgta ctcaagtaca
    11521 gcctgcggct agtttcctag tttgctcttt gattttcatt gagtataaat agatagaaaa
    11581 gaaaatcttg tacaagttcc tgacaatttc tttcttttcg tgtataatag tggaaaagag
    11641 ctaaaacgag gtatggttat ggaagcagtc ctttactcaa cattccgaaa tcatttaaag
    11701 gactacatga agaaggtaaa tgatgaattt gagcctttga cggtggtcaa taaaaatcca
    11761 gatgaggaca ttgtagttct ttcaaagagc gaatgggaca gtattcagga aaccctgaga
    11821 atcgcccaaa ataaggagtt atcagacaag gttttacgag gaatggataa aattcgcgca
    11881 ggacactagt ctaatttaca gagaatacct gagtgaaatc ttgctgttgt tagaaacaaa
    11941 cttcttgtat ttcataatca ttaggaagtc tactgcaaag taggcttttt ctcaagtctc
    12001 tactaaacta ctatttctaa aaaacaagtt tattttggta aatgtgttcc aaattcccca
    12061 aaacatattc tattttaggt ttgtgaaaat tactttttta tggtagaatg taaaagaatg
    12121 tatgtcattc ggaataacaa taaaatgagg taaaaacatg gaaatcatgt cgcttgcgat
    12181 tgctgttttt gccgtcatca ttggtttagt cattggatat gtcagcatct cagctaagat
    12241 gaaatcatct caggaagctg cagagttgat gcttttaaat gctgaacaag aagcaactaa
    12301 tttacgtgga caagctgagc gtgaagtgga tttacttgtt aatgaagcca aacgtgaaag
    12361 caagtctctt aaaaaagaag cactattgga ggccaaagaa gaagccagaa aataccgtga
    12421 agaagtggac gctgaattca aatcagaacg tcaagaactc aaacaaatcg aaagtcgttt
    12481 gacagagaga gctactagcc ttgaccgtaa ggacgacaat ttgacgagta aagaacaaac
    12541 acttgaacaa aaagaacaaa gtatttctga tagagcgaaa aaccttgatg cgcgtgaaga
    12601 gcaattagag gaagtcgaaa gacaaaaaga agcagaacta gagcgtattg gtgctctgtc
    12661 tcaggcagaa gcacgagata ttatcttggc acagacagag gaaaacttga ccaaggagat
    12721 tgccagtcgt attcgcgaag ctgagcaaga ggtcaaggaa cgttctgaca aaatggccaa
    12781 ggacatcctg gttcaagcta tgcaacgtat cgctggtgaa tatgtagcgg agtcaacaaa
    12841 ctcaacggtt catctgccag acgatactat gaagggacgc attattggtc gtgaaggtcg
    12901 taacattcgt acctttgaaa gtttgacagg ggtcgatgtg attatcgacg atacaccaga
    12961 agtggtgacc ttgtcaggat ttgatccgat tcgtcgtgag attgcccgta tgactatgga
    13021 aatgttgctc aaggatggtc gtatccaccc agctcgtatc gaagagttgg ttgagaaaaa
    13081 ccgtcaagag attgacaata agatccgtga atacggtgag gctgctgcct atgagattgg
    13141 cgcaccaaac cttcatccag acttgatgaa gattatgggt cgcttgcaat tccggacttc
    13201 atatggccaa aatgttttgc gccattcgat tgaggttgct aagttagctg gtattatggc
    13261 cagcgagctt ggtgagaatg cggctcttgc ccgtcgtgct ggattccttc acgacatcgg
    13321 aaaagccatt gaccgcgagg ttgaaggtag ccacgttgaa atcggtatgg aattggcacg
    13381 taagtacaag gaacatccag ttgtggtcaa tacgattgct agtcaccacg gagatgttga
    13441 agctgagagc gtcattgcag ttatcgttgc tgcagcagat gccttgagcg cagctcgtcc
    13501 aggtgctcgt agtgagtctc ttgaaagcta catcaagcgt ctccatgatt tggaagaaat
    13561 tgcgaacggc tttgaagggg tacaaaatag ctttgccctt caagcaggac gtgaaattcg
    13621 tatcatggtc aatccaggaa aaatcaagga cgacaaagtc acaatcttag ctcacaaagt
    13681 tcgtgagaaa attgaaaaca atctcgatta tccaggaaat atcaaggtaa ccgtgattcg
    13741 cgagcttcgt gcagtagatt atgctaaata aataagaaag agcagttgaa aaattactgc
    13801 ttttttgtta cactagatag aaagactgta aaggataatc tggctttttg ccattattct
    13861 agagaaatgt tatttcacag attgactaaa aggagacaca atggcagacc gaggcttact
    13921 aatcgttttt tctggtcctt caggggttgg aaaaggaacg gttagaagag agatttttga
    13981 gagttctgaa aaccaatttc aatattctgt atcgatgacg acacgcgcac aacgtcctgg
    14041 agaagtggac ggtgttgact atttcttccg tactcgtgaa gaatttgaag agctgattcg
    14101 tcaaggacag atgttggaat acgcagaata tgtcggtaac tactatggaa ctcctctgac
    14161 ctatgtcaat gaaaccttgg acaagggaat cgatgttttc cttgaaattg aagttcaggg
    14221 tgctcttcag gtcaagaaaa aggttccaga tgctgtcttt atcttcctga caccaccaga
    14281 tttggatgaa ttgcaagatc gcttggtagg tcgtggaaca gatagtgcag aagtgattgc
    14341 ccaacgaatc gaaaaggcca aggaagaaat tgccctcatg cgtgagtatg attatgcgat
    14401 tgtcaacgat caggtgcccc tagctgctga acgtgtcaaa tgtgtgattg aagcagaaca
    14461 cttctgtgtg gatcgtgtca ttggtcacta tcaggagatg ttaccaaaat ctccaactac
    14521 ccgataaaat ttagaaaata ggtacaagca aatgatgtta aaaccctcta ttgatacctt
    14581 gctcgacaag gttccttcaa aatattcact cgtaatcttg gaagcaaaac gtgcccacga
    14641 attggaagca ggtgccccag caactcaagg tttcaagtct gaaaaatcaa ctcttcgcgc
    14701 tttagaagaa atcgaatcag gaaacgttac aattcaccca gatccagaag gaaaacgtga
    14761 agcagtgcgt cgccgtatcg aagaagagaa acgccgcaaa gaagaagaag aaaagaaaat
    14821 caaagagcaa attgctaaag aaaaagaaga tggtgaaaaa atttaaggtt ggggggactc
    14881 aatcttattt tttctattgc aagaatgtac tgacaaggag gaggtgagaa gatggcccta
    14941 gctaagatta tcgtagatgt gcccttgatg cagacggacc agccctatag ttacaggatt
    15001 ccggaggaat ttgagggaat gctggaagtt gggatgcggg ttcatgtacc ttttggtaag
    15061 ggtaatcgcc tgattcaagg gattgttctt ggtttggagt cccaatcaga tggagaagag
    15121 atggagcaag atttaaaaga tattgcagag gtgctggatt tttctcctgt tctcacgcca
    15181 gaacaactct ggctggctga ggagttacgc aaatctgtct tctcctacaa aatctctatc
    15241 ctcaaggcca tgcttccagg atttctgaat tctagctatg acaagattct ctatcctctg
    15301 gaaggcttga gtcaggaaga acgagtacgc ctgtttggtt cagaagattc gctagccttt
    15361 tcttcactag accttgccaa gcaagctgaa atgatgcgtt tgactagaaa aggcctgctt
    15421 ggtctggaat atcaggcagt cgatcaaaag aaggtcaaga cccagtcttg gtatgaggtt
    15481 gaccatgccc aattagaagg tgttgagatt tctacacgtg ccaagaaaaa gttggaactg
    15541 agagattatc tgctgtctca tccagagagc gcttccttgg ctagcttgtt agagtcctac
    15601 tcgcgagagc aagtcaactt ctttgtggat caaggtgctg ttaccatagt ccaaaaggaa
    15661 gttcaacgct cggctgctta ttttgaagga attgaagcaa gtagaccttt ggagttaaat
    15721 ccagaacaaa gacaggcgcg tgatgcggtt gtgagttcta ttggcagttc tcaacctccc
    15781 tttctacttc aagggattac aggaagtggg aagaccgagg tttacttgca gattatccaa
    15841 ggtgccctgg ataagggcaa gacagctatt ttgctggtac ctgagatttc cttgactcct
    15901 cagatgaccg agcgttttat agcacgtttt ggggacaagg tagccattct tcactcagga
    15961 ttatccaatg gtgaaaagta tgatgaatgg cgcaaggtgg agcgtggcga tgcccaagtt
    16021 gttgttggtg ccagatctgc tatctttgct cctctgaaaa atctgggtgt catgattatt
    16081 gatgaagagc atgaagcggc ttataagcag gacagcaatc cccgttacca tgccagagag
    16141 gtagctattt tacgggctca gtataatcaa gcaactctgg tacttggatc tgcaacgccg
    16201 agcttagaga gccgggcgcg tgctggcaaa ggcgtctatc aacacttacg tctaacccaa
    16261 cgtgccaatc ctttggctac aatccctgag gttcaagtga ttgactttcg agactatatc
    16321 ggacaaaatg agacgtcaaa ctttacgcct cctttgctag aggctatcca agaccgtctg
    16381 gttaaaaaag agcaggtggt tctcatgctc aatcgccgtg gttattctag ctttgtcatg
    16441 tgtcgggagt gtgggacggt ggatacttgt cccaactgcg atatttctct gaccttgcat
    16501 atggatacca agactatgaa ctgccattat tgtggtttct cgaaggatat tcctcaggtc
    16561 tgtcctaact gtaagagcca cagtattcgt tactatggga cgggaactca gaaggcttat
    16621 gatgagctag cagaactctt tccccaagct cgcattctga ggatggatgt ggatacgact
    16681 cgaaaaaaag gcagtcacca agccttgctt gatcagtttg ggcgagggaa agcggatatt
    16741 ttacttggta ctcagatgat tgcaaagggt ttggattttc ccaatgttac cctagtcgga
    16801 gttctaaatg cggatacggc cttgaatctg cctgatttcc gttcttctga gagaaccttc
    16861 cagctcttga ctcaggtggc aggtcgagca ggtcgggctg aaaaagcagg tcaagtcttg
    16921 atacagtcct acaattcgca gcactatgct attcgatttg ccaaggatca agattacgaa
    16981 ggcttttatg cctatgaaat gggaatcaga cgacaactcg gctatccacc ttactatttc
    17041 acgattggta ttaccctttc tcacaagaaa gaagaagagg ttttcaaacg tgcctatgaa
    17101 gtcatgaaca ttttgcggtc aggcttgtca gagaccagtc ccattctggg gccaacgcca
    17161 aaaccgattg cccgtaccca caacctctat cattaccaga ttttaattaa ataccgttta
    17221 gaagatgagc tggggccgac cctcaaccag gtcttggcct tgactcaaga acgggaaaat
    17281 agtgagctcc gtctcagcat tgaccatgag ccgcagcaat ttttataaaa aggagaagat
    17341 atgacaaaac taatctttat ggggaccccc gacttttcag caacagtctt aaaaggactt
    17401 ttgacagatg accgttacga aattctagcc gttgtgaccc agccagaccg tgctgttggt
    17461 cgtaaaaaag ttatccaaga aaccccagtc aagcaggctg ccaaggaagc aggactatct
    17521 atctaccaac ctgaaaaatt atctggaagt ccagagatgg aagatcttat gaagctagga
    17581 gcagatggaa ttgtgactgc tgcttttggg cagtttctcc caagcaaact ccttgatagc
    17641 atggactttg ctgtcaacgt tcatgcctcc ctccttccta gacaccgtgg tggtgcgcct
    17701 atccattatg ccttgattca aggggatgag gaagctggtg tgaccatcat ggaaatggtt
    17761 aaggaaatgg atgcaggaga tatgatttct cgtcgcagca ttccgatcac agatgaggac
    17821 aatgttggca ccttgtttga aaaattggcg ctagttggtc gtgatttgct tttggacact
    17881 ctgcctgcct atattgctgg tgatatcaaa cctgaaccgc aggatacgag tcaggttacc
    17941 ttctctccaa atataaagcc agaggaagaa aaactggact ggaacaaaac caatcgtcaa
    18001 ctctttaacc aaattcgtgg aatgaacccc tggcctgttg cccatacttt ccttaagggc
    18061 gaccgcttta agatttatga agccctacca gtagaaggtc agggaaatcc aggtgagatt
    18121 ctctctatcg gcaagaaaga attgattgtc gcaacggctg aaggggctct atccctcaaa
    18181 caagtgcagc cagctggtaa gcctaagatg gacattgctt ccttcctcaa cggagttgga
    18241 cgtacattga ctgtaggaga acgatttggt gactaaagta gaaacggcta gaagtttagc
    18301 tctagcagtg ctagaggatg tttttgtgaa ccaagcatac tcaaatatcg ccttaaataa
    18361 gcatctaaag ggaagtcaac ttttggcagc agacaagggc ttagtgaccg agctggtcta
    18421 tggaacggta gcccgtaaac tgactctgga atggtaccta tcccacttta tcgaagacag
    18481 agaccagtta gacagctggc tctatgtcct tcttctcatg agtgcctacc aactccgcta
    18541 tttggacaag attccagatc atgctgtggt caatgaagca gtggaattgg ccaaacttcg
    18601 taaaaaaggc agtgaaaaat tggtcaatgc cctccttcgc cgtatcttgc gtgaaggctg
    18661 gccagatatt tctagcatca agcgaaaaaa caagcgtgac tccattgcct attctctccc
    18721 agtttggcta gttgccaaac tcaaggaaga atacggagag gagagagcaa aagccatctt
    18781 tgaaagcttg ttagtgcgaa acaaagccag tattcgtgta acagacctaa gtcgaaaaga
    18841 ggaaatccaa gccttgttgg aggcgaataa ttccctttta gcaaccactg gtctggttaa
    18901 ggagcagggg cattttgcag ggcataattt gtttgcggat ggagccatta ccatccaaga
    18961 cgagtccagt cagctggttg ctccgacgct tgatttacaa ggtgatgagc gagtgcttga
    19021 tgcctgtgcg gctccaggtg ggaaaacagc ccatatagcc tcttatctta cgacaggtca
    19081 ggttactgct ctggacttgt acgaccacaa gttggattta attcaagaaa atgcccaacg
    19141 tctgggagtt gcagatcggg ttcaaactca aaaattggat gccagaaagg tgcatgagtt
    19201 ttttgaccag gattcctttg ataagatttt ggtggatgct ccttgttcag gaatcggtct
    19261 tttgcgccga aaaccagata tcaaatacaa taaagaaacg gcagatttcg cgtccttgca
    19321 ggaaattcag ttagaaatat taggtagtgt ttgtcaaata ctaggcaaag gtggtataat
    19381 aacttatagc acctgcacta tcgtctcaga ggagaatttt caagtcgtta aggccttttt
    19441 agagagtcat cccgagttcg agcaggtaaa actagaacat gaatgtaagg atatcatgaa
    19501 agacggctgt atcctcatta cacctgaatt gtatggaagt gatggattct tcatcagtca
    19561 atttcgcaag atatcggatt aggaaggaac tgacacatgg aaatttcatt attaacagat
    19621 gttggtcaga aacgaacaaa taaccaagac tatgtcaacc actatgtcaa tagagctgga
    19681 cgtaccatga ttattttagc tgatgggatg ggaggtcatc gcgcagggaa tatcgctagt
    19741 gaaatggcgg tcacagacct gggtgtagct tgggttgata ctcagatcga tacagtcaat
    19801 gaagtgcgtg aatggttcgc ccattaccta gaaattgaaa atcaaaagat tcaccagctt
    19861 ggtcaggatg aagcttacag aggcatggga actactttgg aagtccttgc tattattgat
    19921 aatcaggcta tctatgctca tattggtgat tcgcgtatcg gcttgattcg tggagaagaa
    19981 taccatcagt tgacgagtga tcattctttg gttaatgaat tgctcaaggc tggtcaattg
    20041 acaccagaag aggcagaagc tcatccgcaa aaaaatatta tcacccagtc tattgggcaa
    20101 aaagatgaaa ttcagcctga ttttgggaca gttatccttg agtcaggtga ctatctcttg
    20161 ctcaatagtg acggcttgac caacatgatt tcaggcagtg agattcgtga tattataacc
    20221 agtgatattc ctttagcaga taaaacggag acacttgttc gttttgctaa caatgcagga
    20281 ggtttagaca acattacggt tgcccttgtt tctatgaacg aggaggatga agaatgatcc
    20341 aaatcggcaa gatttttgcc ggacgctatc ggattgtcaa acagattggt cgaggaggca
    20401 tggcggatgt ctacctagcc aaagacttaa tcttagatgg ggaagaagtg gcagtgaagg
    20461 ttctgaggac caactaccag acggacccga tagctgtagc tcgttttcag cgtgaagcga
    20521 gagctatggc agatctagac catcctcata tcgttcggat aacagatatt ggtgaggaag
    20581 acggtcaaca gtatcttgca atggagtatg ttgctggact agacctcaaa cgctatatca
    20641 aggaacatta tcctctttct aatgaagaag cagtccgtat catgggacaa attctcttgg
    20701 ctatgcgctt ggcccatact cgaggaattg ttcacaggga cttgaaacct caaaatatcc
    20761 ttttgacacc agatgggacg gccaaggtca cagactttgg gattgctgta gcctttgcag
    20821 agacaagtct gacccagact aactcgatgt tgggctcagt tcattacttg tcaccagagc
    20881 aggcgcgtgg ttcgaaggcg actgtgcaga gtgatatcta tgccatgggg attattttct
    20941 atgagatgtt gacaggccat atcccttatg acggggatag cgcggtgacc attgccctcc
    21001 agcatttcca gaaacccctg ccgtccgtta ttgcagaaaa tccatctgta cctcaggctt
    21061 tagaaaatgt tattatcaag gcaactgcta aaaagttgac caatcgctac cgctcggttt
    21121 cagagatgta tgtggacttg tctagtagct tgtcctacaa tcgtagaaat gaaagtaagt
    21181 taatctttga tgaaacgagc aaggcagata ccaagacctt gccgaaggtt tctcagagta
    21241 ccttgacatc tattcctaag gttcaagcgc agacagaaca caaatcaatc aaaaacccaa
    21301 gccaggctgt gacagaggaa acttaccaac cacaagcacc gaaaaaacat agatttaaga
    21361 tgcgttacct gattttgttg gccagccttg tattggtggc agcttctctt atttggatac
    21421 tatccagaac tcctgcaacc attgccattc cagatgtggc aggtcagaca gttgcagagg
    21481 ccaaggcaac gctcaaaaaa gccaattttg agattggtga ggagaagaca gaggctagtg
    21541 aaaaggtgga agaagggcgg attatccgta cagatcctgg cgctggaact ggtcgaaaag
    21601 aaggaacgaa aatcaatttg gttgtctcat caggcaaaca atccttccaa attagtaatt
    21661 atgtcggccg gaaatcttct gatgttatcg cggaattaaa agagaaaaaa gttccagata
    21721 atttgattaa aattgaggaa gaagagtcga atgagagtga ggctggaacg gtcctgaagc
    21781 aaagtctacc agaaggtacg acctatgact tgagcaaggc aactcaaatt gttttgacag
    21841 tagctaaaaa agctacgacg attcaattag ggaactatat tggacggaac tctacagaag
    21901 taatctcaga actcaagcag aagaaggttc ctgagaattt gattaagata gaggaagaag
    21961 agtccagcga aagcgaacca ggaacgatta tgaaacaaag tccaggtgcc ggaacgactt
    22021 atgatgtgag taaacctact caaattgtct tgacagtagc taaaaaagtt acaagtgttg
    22081 ccatgccgag ttacattggt tccagcttgg agtttactaa gaacaatttg attcaaattg
    22141 ttgggattaa ggaagctaat atagaagttg tagaagtgac gacagcgcct gcaggtagtg
    22201 tagaaggcat ggttgttgaa caaagtccta gagcaggtga aaaggtagac ctaaataaga
    22261 ctagagtcaa gatttcaatc tacaaaccta aaacaacttc agctactcct taaaagcaga
    22321 tggataatca aaatgagtaa tcaatctttg tcatgatttc atggcaaaga ttttttttga
    22381 gtccagattt gtgatagaat agagggagtt gataaaagga ggaaagcatg gaagaatcaa
    22441 aagaattaaa tgccgtcatt gatgtgatta tgctagcggg gactattctc cttaaaagtg
    22501 gctcagaaat ccatcgtgta gaagatacca tgattcgaat cgcgcattcg caggggattg
    22561 tggattgcaa tgtccttgcc atgcctgccg ctatcttttt ctctattgaa aataccaata
    22621 tttcgcgcat gaagcgcgtg acctcctctt cttataacat cgaaaaagtc tgcgatgtga
    22681 accagatttc tcgtcagcta gttggggggc agattgactt agaaacagcc tttaagcaat
    22741 tgacggcctt gcaagctcaa ccccttccct atactaagtt gcaggtaact ctggctgcga
    22801 cctttagtgc tcctttcttt tcagttatgt ttagcggaaa tatctacgac gcacttgggg
    22861 caggagtggc gaccttattt ggttttgcct tttccctcta tgtggaaaaa tttatccgaa
    22921 ttccctttgt gacagccttt gctggagcct ttgtctttgg gataattgcc cagttttggg
    22981 ctcgctacac aggttttcct tcaacggcag atttgattat agctggtgcg gtcatgccgt
    23041 ttgtaccagg tattgccttg accaatgcgg tccgtgatat tatgaccaac cacataaact
    23101 ctggtatgag taagatgttt gaatccctgc tcattaccct cgctttaggg gcaggaactt
    23161 ctgtcgcctt ggtattgatg aactaatatg acactaacaa cctttttatt acaagcagta
    23221 gcaagttttc ttgccattat cactttttta atcgtactca atgtgcaacg gtctatgctc
    23281 ttacctggag ggattttggg catgactgtc tggctaatct atctcttgct caaggaaccg
    23341 accaatgtca ttgtagctac cttcattgca gccattattg gttcttgtgt cagccagatt
    23401 ttaagtattc tttataagac acctgctgtg gtctttatct tggccatttt ggcaccgctg
    23461 gttccaggtt atctctccta ccgaacaact gccttttttg tgacagggga ctataataaa
    23521 gcactggcaa gtgcgacctt ggttgtcatg ttggctttgg taatctctat tggaatggct
    23581 agcggaacag tgattctcag actgtatcat tatataaaaa cacatcgagt atcgtagact
    23641 ttacagaaat aaaagaattt tctgaaaaat gagataaata aattaacaac gctttctata
    23701 tgtgcgagaa taccgcactt atgaagaaat tgcggctgat tttggtatcc acgaaagcaa
    23761 cttactccgt cggagccaat gggttgaagt aactcttgtt caaaggtggt gttacgattt
    23821 caagaactcc tctcagttct gaagacacgg taatgattga tgcgacggaa gtaaaaatca
    23881 atcgccctaa aaaaaacaat tagcgaatga ttctggtaaa aagaaatttc acgctatgaa
    23941 ggctcaagcg attgtcacaa gtcaagggag aattgtttct ttggatatca ctgtgaacta
    24001 ttgtcatgat atgaagttgt tcaaaatgag tcgcagaaat atcggacaag
//
LOCUS       DAVAGB010000030        23495 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVAGB010000030 DAVAGB010000000
VERSION     DAVAGB010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23495
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.030"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(45..893)
                     /locus_tag="VQO19_001373"
     CDS             complement(45..893)
                     /locus_tag="VQO19_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET1349625.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            1045..1323
                     /locus_tag="VQO19_001374"
     CDS             1045..1323
                     /locus_tag="VQO19_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349626.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            1325..3388
                     /locus_tag="VQO19_001375"
     CDS             1325..3388
                     /locus_tag="VQO19_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET1349627.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(3466..4722)
                     /locus_tag="VQO19_001376"
     CDS             complement(3466..4722)
                     /locus_tag="VQO19_001376"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HET1349628.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            4864..7326
                     /locus_tag="VQO19_001377"
     CDS             4864..7326
                     /locus_tag="VQO19_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET1349629.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMTKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNVIQQASPSIWGNEHFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSRARR"
     gene            7391..8302
                     /locus_tag="VQO19_001378"
     CDS             7391..8302
                     /locus_tag="VQO19_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET1349630.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            8532..9230
                     /gene="dapD"
                     /locus_tag="VQO19_001379"
     CDS             8532..9230
                     /gene="dapD"
                     /locus_tag="VQO19_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HET1349631.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            9298..10428
                     /locus_tag="VQO19_001380"
     CDS             9298..10428
                     /locus_tag="VQO19_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HET1349632.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            10440..10979
                     /locus_tag="VQO19_001381"
     CDS             10440..10979
                     /locus_tag="VQO19_001381"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HET1349633.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGRTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            10963..11640
                     /locus_tag="VQO19_001382"
     CDS             10963..11640
                     /locus_tag="VQO19_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HET1349634.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            11654..11731
                     /locus_tag="VQO19_001383"
                     /pseudo
     CDS             11654..11731
                     /locus_tag="VQO19_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(11941..12876)
                     /locus_tag="VQO19_001384"
     CDS             complement(11941..12876)
                     /locus_tag="VQO19_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349635.1"
                     /translation="MENKFVEFIENNKKVIISSVAVGVVLVLGFGWYSYNQQQAEQQA
                     KIVQLEKDSKSDKEQVDKLFESFDASSDESISKLKELSETSLKTDAGKDYLNNKVKES
                     SKAIVDFHLQKGLAYDVKDSDEKFKDKATLETNVKEITKQIDFIKKVDETFKQENLEE
                     TLKSLNDLVDKYQKQIELLKKEEEKAAEKAKESSSQSNSSSGASNESYNGSSNSNVDY
                     SSSEQTNGYSNNYGSQSYSGSGDSSTNGGSSEQYSSSNSNSGVNNGYYKKYKNIGADG
                     HVSYTYDNESNGDVFDENWNYLGNTGGGIAEPPQR"
     gene            complement(13294..14193)
                     /gene="galU"
                     /locus_tag="VQO19_001385"
     CDS             complement(13294..14193)
                     /gene="galU"
                     /locus_tag="VQO19_001385"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HET1349636.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFKGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(14215..15231)
                     /locus_tag="VQO19_001386"
     CDS             complement(14215..15231)
                     /locus_tag="VQO19_001386"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HET1349637.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGNALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            15443..15823
                     /locus_tag="VQO19_001387"
     CDS             15443..15823
                     /locus_tag="VQO19_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET1349638.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVLIR
                     FLKSIMIGYLRKKDLSSQIIHIWH"
     gene            complement(15997..16422)
                     /locus_tag="VQO19_001388"
     CDS             complement(15997..16422)
                     /locus_tag="VQO19_001388"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET1349639.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMIGCLAYNLYLFLKQLAGDEVKSLTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(16490..17140)
                     /gene="phoU"
                     /locus_tag="VQO19_001389"
     CDS             complement(16490..17140)
                     /gene="phoU"
                     /locus_tag="VQO19_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET1349640.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKTLLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLSDLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(17155..17907)
                     /gene="pstB"
                     /locus_tag="VQO19_001390"
     CDS             complement(17155..17907)
                     /gene="pstB"
                     /locus_tag="VQO19_001390"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET1349641.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWDEVKDNLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(17909..18724)
                     /gene="pstA"
                     /locus_tag="VQO19_001391"
     CDS             complement(17909..18724)
                     /gene="pstA"
                     /locus_tag="VQO19_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET1349642.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(18717..19580)
                     /gene="pstC"
                     /locus_tag="VQO19_001392"
     CDS             complement(18717..19580)
                     /gene="pstC"
                     /locus_tag="VQO19_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET1349643.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFIANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(19698..20573)
                     /locus_tag="VQO19_001393"
     CDS             complement(19698..20573)
                     /locus_tag="VQO19_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HET1349644.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(20740..22071)
                     /locus_tag="VQO19_001394"
     CDS             complement(20740..22071)
                     /locus_tag="VQO19_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HET1349645.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(22072..22779)
                     /locus_tag="VQO19_001395"
     CDS             complement(22072..22779)
                     /locus_tag="VQO19_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET1349646.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(22863..23339)
                     /locus_tag="VQO19_001396"
     CDS             complement(22863..23339)
                     /locus_tag="VQO19_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET1349647.1"
                     /translation="MDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALYTSI
                     YFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKSTIWGSTVDKDYALVSCLVAPGFEFEDFELFERADLLATYPEHKEMIEHLTRY"
     gene            23340..23495
                     /locus_tag="VQO19_001397"
                     /pseudo
     CDS             23340..23495
                     /locus_tag="VQO19_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT         6849 a         4457 c         4990 g         7199 t
ORIGIN      
        1 aaccatacgt acggcaaggc gacgttgacg tggtttgaag agtattagaa tgctttccca
       61 accagaatct ctgcttcgat ggtaatctct gtcagttggc tccagtcaat cttgctctgg
      121 tcaacgtgaa agaggagagg agtcatactg agtagggctt ggagttgttc tgctgtgata
      181 gtcttagtca gagaggcagt ttgactagat aggatggtaa agtgttcctg gaaatgctcc
      241 ttgatatctt ggttagaata ctccttgttt gtcagctggt cctgtactct ttgacggatt
      301 tctttgaggt gattttcagt tgggataacc tttatcaaga taccgtcttt ggataaaacg
      361 cgacgaaatt ctccatagtt ggcaggtgag aagatatcaa gcagaatatc catgttagcg
      421 tcttttatag gaaggcgtgc caagtcgcca acgaaccaat tgactgccca gttgggttca
      481 cttttagcag cgatttggac tgaatctttg gagatgtcaa aggcatagaa agttttttca
      541 gagtgacttt cttgtagttt gcgagaatag aatccttcac cacaaccgat atccaaaatt
      601 gttgtggtag tttttgagct tgcaagcaag tcagatacag catctaagat agcttggtaa
      661 aagccggctt ctaggatttg ttgacggttt tgaaaatttt ccttgtcata gttagcagat
      721 tgcttgattt gaggtgctag attgacatag ccaaatttcg ccaagtcaaa agaatgacgg
      781 ttgcagcact tgaaattagt ctctaacaga gtcagatttt cttgacagat aggacaggca
      841 aaggcagtcg cagaagcaaa acgctgaagt ttgggcttga gatttgtatt catagtttaa
      901 gtgtatcaaa agaggcaaat gaaagcaact ttaggaataa gtagatggga gattcagtag
      961 aaataaaact aattctccaa tttatagaat gaaattgctt ttatatctaa attgctatat
     1021 aataatgata aggaggaaat aagtatgtta aaagaagtat taaccgttgc aaaagttgcg
     1081 aaaaaatctt cattattttt gggtggtgtc gcatttggta cccttggttt gaaaatctta
     1141 gcaagtaagg aagctaaaaa aggttattct aaagctttgg ctaaggctta caagttgaaa
     1201 gacgagctag atgcatctgt ttctgttgtg aagcaacatg gagacgatgt cttgcaagat
     1261 gccaaatatt tgtacgagca agagaaaaaa gaagagcaat tagatagcct tataggtgaa
     1321 taatatgtct tttaaagtgc tacatagagg ataccaacat atccgactat catcttcttt
     1381 ttcacttacc ttggatattc aagactatct tcgttccttg gcgagagatg aaaaggggat
     1441 tgagtctatc cagttttaca tggatcaaca gcactttact ctacgcataa aagaaggctt
     1501 ttctgtatta gataatgcag aagccttttt aaaaagaatt gataaaggga aagtttctga
     1561 gttgatgact cttcccattc gtagagaaga gagtgcttat tctattgttt caggtgcagc
     1621 ggttaagcgt gtactttttc gtagttttgt gccgtatcct attcgctata tatggacttg
     1681 ttatcaggct ttgggttata ttagagaagc ctatcaaaca ctagcgcgta aggaactaac
     1741 gatggaagtc ttggactgtt cggctatttt attgtctttg tttatgaacc aatccaagac
     1801 agctagcaat atcatgttta tgcttgattt ggggaatcat ttagatcagt ggtccttgaa
     1861 aaaaactgca acagatttag aacagagtct tcttgcaaaa gagagcgatg tattcctagt
     1921 acagggcgat acggttgtta gtatcaagag ttccgatgtt caaataggag atgtcttgat
     1981 cttatctcaa ggaaatgaaa ttctgtttga tggacaagta gtttcaggtt taggtatggt
     2041 caacgaaagt tccttgacag gagagagttt tccagttgaa aaaagagagt ctgatttagt
     2101 ttgtgcaaat acagtattag aaactggaga gttacgcatt cgtgtaacag ataatcagat
     2161 gaacagccgt attttacagc tgattgagtt gatgaagaaa tctgaagaaa acaagaaaac
     2221 gaaacaacgc tatttcatca agatggcgga taaagtcgtc aaatataatt tcttgggggc
     2281 tgggctgact tacctattga caggttcttt ttctaaggct atttctttcc tattggtcga
     2341 tttctcctgc gctttgaaaa tctctactcc tgtagcttat ttgacagtta tcaaggaagg
     2401 gttgaaccgt gaaatggtga ttaaggatgg agatgttctg gagaaatatc tggaagttga
     2461 tactttcttg tttgataaga caggaacaat cacaactagt tatcctatag ttgaaaaggt
     2521 gttacctttt ggagactata gtgaggaaga tattctcaga atcagtgcct gtcttgagga
     2581 acacatttat catcctattg ctaatgccat cgtcaagcaa gctgagatag agggaattga
     2641 acatgaggaa atgcatggga aactccaata tatcgcaagc aaggggatca aatctcatat
     2701 agatggccaa ccagttctta ttgggaatta tgtcttgatg caggatgagc agattcatat
     2761 cagttcagaa caaaatgctt taattgaaga gtacaagagt cactacaatc tcttattctt
     2821 ggcttatcaa aatgaattga ttggaatgtt ctgcattcat actcctttga gaaaagaagc
     2881 aaaaacagcc ttggataaac ttaaggcaca ggggaaaaaa ttgattctgg caacaggaga
     2941 caccttgatt aggacagagg aattagtcaa agatttgccc tttgatcagg tctatacaga
     3001 cttgaaacct gatgggaaat ttgagttagt agagaaactg cagaaagcag gtcacactat
     3061 tttgatggtt ggagatggat tgaatgactc agcggcttta actctatcag atatcggtgt
     3121 ggtgatgaat gagagtgcag atatttctaa gcagatgagt gatatcttat tgttagataa
     3181 tcgtttggat ttcttccaag agttggattc gttatcatca tctttgcaaa cactcatcaa
     3241 gaaaaatatt caagataccg ttgtcgtaaa tagtagtttg attggcttcg gcttatttaa
     3301 ttggctcagt ccttcaaatc tctctatctt acataatcta acaaccttgc gcattgtcct
     3361 gcgtagcctg tctattaaaa atagatagat gagagttatt aacagcaaaa aggagttacc
     3421 tttctcgagg ttaactcctt tgtttataga taaatgttga atagtttagt aagtcaatac
     3481 aaagtatttt ttcttcccac gacggataac agtcagttca ttttctaact tatcagcgtc
     3541 actcaagaca tagtcaaggt cttggatgcg gtcgccgttt acgtagatgg ctccgttttg
     3601 gacgtcttca cgggcttggc gttttgagtt aactatacca gatgagacga gcagttccac
     3661 gatattgttg ttttcgtctg cctgtacttg gtagtttggc acaccacgaa gtccttgttt
     3721 gagctctttg acagaaaggt ttttgatgtt tcctgcaaag agttgctcag tgatgttaag
     3781 tgcttctttg taggcttctt ctccgtgaac aagtgtaaca acttcacgag ccaagacttt
     3841 ttgagccaag cgttcgtgtg gcgctgcttc aaattgttta cgaatatctt caatctcatc
     3901 aagtgacaag aaagtaaaga ttttcaagaa gcgaacagcg tcagcgtcca tcacgttcat
     3961 ccagaattgg tacatttcgt atggagaagt cttttcggga ttgagccaga cggcatttcc
     4021 ttctgattta ccaaattttt taccagttgc atctgtgatt agtggaacag tgataacgtg
     4081 accagtcttg tccgccttac gacgaagcaa ttcggtacca gctgtcatat ttccccactg
     4141 gtcagaacca ccgatttgaa gagtgacatt atggtcttgg ttaaggacga agaagtcgta
     4201 cccttgcatg atttggtaag cgaactcagt gtaagaaatt cctgtttcga tccgtttttt
     4261 aacagattcc ttactcatca tgtagttgac cgtgaagtat tttccaatat cacggaggaa
     4321 gtcaatgaag ctgatgctgc caaaccagtc gtagttgttg accatgacag ccttgttttc
     4381 gccattttca aagtcaagaa aacgagaaag ttgtccttgg atagacttga cccagccatc
     4441 tactgtgtct tttgtttgga gactacgttc agcatctttg aaggacggat ctccgatgag
     4501 acctgtagca ccgccaacga gcgcataagg tttgtgacct gctagttgca agcgacgact
     4561 tgtcaagatt gcgacaaggt ggcctaggtg aaggctgtca gcagttggat cgtagccagt
     4621 ataataagaa acttgacctt cttctagggc tttacgcaaa gcttcttcat cagtcgtttg
     4681 aaatatcaaa ccacgctctt ttagctcatc aaaaatgtgc atgtgtcttt tctccttttt
     4741 aaaattattg tttctaccta ttgtatcaca aacttgggca atagcctagc agaataggga
     4801 agaaagtggc tattttattg aaaatttccc ttttgtggta taatagataa agtgaggaaa
     4861 tccatgcaaa atcaattaaa tgaattaaaa cgaaaaatgc tggaattttt ccagcaaaaa
     4921 caaaaaaata aaaaatcagc tagacctggc aagaaaggtt caagtaccaa aaaatctaaa
     4981 accttagata agtcagccat tttcccagct attttactga gtataaaagc cttatttaac
     5041 ttactctttg tactcggttt tctaggagga atgttgggag ctgggattgc tttggggtac
     5101 ggagtggcct tatttgacaa ggttcgggtg cctcagacag aagaattggt gaatcaggtc
     5161 aaggacatct cttctatttc agagattacc tattcggacg ggacggtgat tgcttccata
     5221 gagagtgatt tgttgcgcac ttctatctca tctgagcaaa tttcggaaaa tctgaagaag
     5281 gctatcattg cgacagaaga tgaacacttt aaagaacata agggtgtagt acccaaggcg
     5341 gtgattcgtg cgaccttggg gaaatttgta ggtttgggtt cctctagtgg gggttcaacc
     5401 ttgacccagc aactaattaa acagcaggtg gttggggatg cgccgacctt ggctcgtaag
     5461 gcggcagaga ttgtggatgc tcttgccttg gaacgcgcca tgactaaaga tgagatttta
     5521 acgacctatc tcaatgtggc tccctttggc cgaaataata agggacagaa tattgcaggg
     5581 gctcggcaag cagctgaggg aattttcggt gtagatgcca gtcagttgac tgttcctcaa
     5641 gcagcatttt tagcaggact tccacagagt cctattactt actctcctta tgaaaatact
     5701 ggggagttga agagtgatga agacctagaa attggcttaa gacgggctaa ggcagttctt
     5761 tacagtatgt atcgtacagg tgcattaagc aaagacgagt attctcagta caaggattat
     5821 gaccttaaac aggacttttt accatcgggc acggtcacag gaatttcacg agactattta
     5881 tactttacaa ctttggcaga agctcaagaa cgtatgtatg actatctagc tcagagagac
     5941 aatgtctccg ctaaggagtt gaaaaatgag gcaactcaga agttttatcg agatttggca
     6001 gccaaggaaa ttgaaaatgg tggttataag attactacta ccatagatca gaaaattcat
     6061 tctgccatgc aaagtgcggt tgctgattat ggctatcttt tagacgatgg aacaggtcgt
     6121 gtagaagtag ggaatgtctt gatggacaac caaacaggtg ctattctagg ctttgtaggt
     6181 ggtcgtaatt atcaagaaaa tcaaaataat catgcctttg ataccaaacg ttcgccagct
     6241 tctactacca agcccttgct ggcctacggt attgctattg accagggctt gatgggaagt
     6301 gaaacgattc tatctaacta tccaacaaac tttgctaatg gcaatccgat tatgtatgct
     6361 aatagcaagg gaacaggaat gatgaccttg ggagaagctc tgaactattc atggaatatc
     6421 cctgcttact ggacctatcg tatgctccgt gaaaagggtg ttgatgtcaa gggttatatg
     6481 gaaaagatgg gttacgagat tcctgagtac ggtattgaga gcttgccaat gggtggtggt
     6541 attgaagtca cagttgccca gcataccaat ggctatcaga ccttagctaa taatggagtt
     6601 tatcatcaga agcatgtgat ttcaaagatt gaagcagcag atggtagagt ggtgtatgag
     6661 tatcaggata aaccagttca agtctattca aaagctactg cgacgattat gcagggattg
     6721 ctacgagaag ttctatcctc tcgtgtgaca acaaccttca agtctaacct gacttcttta
     6781 aatcctactc tggctaatgc agattggatt gggaagactg gtacaaccaa ccaagacgaa
     6841 aatatgtggc tcatgctttc gacacctaga ttaaccctag gtggctggat tgggcatgat
     6901 gataatcatt cattgtcacg tagagcaggt tattctaata actctaatta catggctcat
     6961 ctagtaaatg tgattcagca agcttcccca agcatttggg ggaacgagca ctttgcttta
     7021 gatcctagtg tagtgaaatc ggaagtcttg aaatcaacag gtcaaaaacc agggaaggtt
     7081 tctgttgaag gaaaagaagt agaggtcaca ggttcgactg ttaccagcta ttgggctaat
     7141 aagtcaggag cgccagcgac aagttatcgc tttgctattg gtggaagtga tgcggattat
     7201 cagaatgctt ggtctagtat tgtggggagt ctaccaactc catccagctc cagcagttca
     7261 agtagtagtt ctagcgatag cagtaactca agtactacac gaccttcttc aagggcgaga
     7321 cgataattct ctaaatgaag tggccaatca atggattgcc acttttttcc tttcgtgtta
     7381 caataagggt atgaatcagt atcagaaaaa gattgttaac ggaaaaattt attcgctcct
     7441 atccggctta atatggggaa tctgtggaat tttaggagag tacttcttta ctcattatca
     7501 ggtgtcttcg ggctggatta cctctatgcg tttgacactg gcagggagtc ttgtactcat
     7561 ttggtctgca atacaattaa aatcgcaagt gctagatatt tggcgagaca agaaaaatta
     7621 cctgcccttt ttagcctatg ctattttggg gattttttca gttcagtatt ttttctatct
     7681 ctgtgtagaa tactcaaatg ctacgacagc aactatttta cagtttatta gccctgtctt
     7741 tatcctcttt tataatcgct tggtttatca aaaacgagcg tcaaaaagcg ctgttttcta
     7801 tgttttggtt gccatgctgg gtgtttgctt gatggcgaca aagggagatc tctctcagtt
     7861 atccatgacg ccgctagctc ttataacagg tttgctgagt gccatgggtg ttatgtttaa
     7921 tgttatcttg ccccaacctt ttgctaagcg ttatggtttt gttcctacgg ttgggtgggg
     7981 gatgattttg gcaggtttgt ttagcaatgt cctctcgccg gtttatcagc tttcctttac
     8041 tcttgatatt tggagtatct tgatttgcct cattatcgct ttctttggaa cggcttttgc
     8101 ttttttcatt tccatgaagg ctgtgtcctt ggtttctcct ttggtggttt ccgttatcag
     8161 tgccagtgaa cctctctctt ctgctctctt gagtgttttg ttcttaggat tagtagtgga
     8221 ttggtccctc cttctagcta tagccttgat tattttaccc atgatatttt tgtctataga
     8281 agaagcgaaa gaaagtagat aaaaagtctt ttcttaattc taaaagtgtg ctatactaga
     8341 atagtcaata aaacacgggg agatagttgt gaagagtgtt tttaggttgt atcggtaggg
     8401 gcttgctttt accgacagca cgttttatct cacaacccta aaaaatcata cctaaaaaca
     8461 gacaaaaagg tttcaaattt gaggcctttt ttggtagaat aggtatcatt ataacgaacc
     8521 aggaggcacc tatgactgct acaaaaatga acgctcaaga aattatccaa tttatcgcca
     8581 atgctgaaaa gaaaaccagt gtcaaagtaa cctttgaggg gcaactcgca actgctgtgc
     8641 ctagctctgt tgtcaaacta ggaaatgtcc tattcggaga ctggaaggac gtggctccgc
     8701 ttcttgaagg tttggtagaa aatcaagatt atgttgtcga gcaagatgct cgtaattctg
     8761 cagttccttt gctagataag cgtgctatca acgctcgtat cgagccaggt gctattatcc
     8821 gtgaccaggt ggaaattggt gacaatgctg ttatcatgat gggagctgtt atcaatatcg
     8881 gtgctgaaat cggtgctgga accatgattg acatgggtgc catccttggt ggccgtgcta
     8941 tcgttggaaa aaatagccac gttggtgcag gtgcagtttt ggcaggtgtg attgagccag
     9001 ctagtgctga accagtccgt gtcggagaca atgttcttat cggtgctaat gcagtggtta
     9061 tcgaaggagt ccaaatcggt agtggttcag ttgtcgcagc aggagctatt gttacccaag
     9121 atgtcccaga aaacgtggta gtagcaggtg ttccagctcg tattatcaaa gaaattgatg
     9181 cccaaactca acaaaaaaca gcgctagagg atgcgcttcg taccttgtaa ttgtaaaagt
     9241 aaaaaagagg cggaaccctt tttccagcct ctttctgcta tatcggagga cagatagatg
     9301 ttagatttga ttcagactag acgagattta caccagatac cagagattgg cttggaggag
     9361 ttcaagactc aggcttattt gctggatgtg attgagaaat tgactacggg caaggatttt
     9421 gttcaaattc gtacttggcg gacagggatt ttggtctacc tgcagggaag tcagccggag
     9481 cgaaccattg gttggcggac agatattgat ggcctgccta tcgtcgaaca aacaggtcta
     9541 ccttttgctt ctcaacacca aggtcgcatg catgcctgtg gtcatgattt tcatatgacc
     9601 attgccttag gctgtcttga gcgcgccctt gaggagcaac ccaagaataa tctgctcttt
     9661 ctatttcagc ctgctgaaga aaatgaagct ggtggtatgc tcatgtatga ggacggtgct
     9721 tttggagatt ggttgccaaa ccaattctat ggtctccatg ttcgtccaga tttgaaagtc
     9781 ggccagattg cgactaatac tcatacactc tttgcaggaa cttgcgaggt gaagatccgt
     9841 ttcaaaggca aaggtggcca cgcagctttt cctcatgaag ccaatgacgc cttggtggcg
     9901 gctagttact ttgtgaccca agtgcagtca gttgttagcc gcaatgtcaa cccaatcgag
     9961 ggagcagtgg tgaccttcgg cgtttttcaa gctggaacca ccaacaatgt catcacagac
    10021 acagcttttt tacatggaac tattcgtgcc ttgacacagg acatgagtct cttggtgcaa
    10081 aagagggtaa aaacagttgc agaaggggtt gcagctgcct ttgatatgga agtcgaagtg
    10141 gaactcaaac aaggtggata cctacctgtt gagaacaatc cagccttggc gcgtgaactg
    10201 atggacttct ttgacgaaaa agacggaatc gagttgattg atatcgaacc tgctatgaca
    10261 ggcgaggact ttggttatct cctttcaaag gttgatggcg tgatgttttg gctaggtatc
    10321 gatagtccct acgctcttca tcaccctcaa atgagtccta aggaagaagt cttagctatt
    10381 ggggtggctg cggtgtctag tttcctgaaa aagaaggcag cagaatagag ggcttgtata
    10441 tgaaatcgga attacgcaag caagtcttgc atgaaatgaa ggctttatct caagaacaaa
    10501 aacaggctat agaccaagct ttaaccgagc gaattttaca acaccccttt tatcaagaag
    10561 ccaaggtcat cgcaacctac ctctcttttt ctcatgagtt tcaaacgcgg gaactgattg
    10621 agcaggcgct gaaggacggc aagaaggttt taatacccaa aacttatccc aaggggcgca
    10681 tggactttgt agtctatgat ccgcagcagt tggtaaaaac tgcctttgcc ttactggagc
    10741 cacagggaga tttggaagtg gtggatgtat ctcagattga tttgattcat gttcctggcc
    10801 tggcttttac gacggatgga tatcggattg gatatggtgg aggttattat gaccgctatc
    10861 tggaacattt ttctggtcgt actttgagta cggttcatcc ttgtcaaatt caggacttta
    10921 tacctgaaaa ccatgatatt cctgttcagg aggtattaat tgatgaagga aatctttgat
    10981 agacgttacc ctgtgacgag tttcttcctc ttagtgacgg ccttggtatt tttactaatg
    11041 ttggtcactg caggcggaaa ctttgacagg gcagatacat tatttcgatt tggagccatg
    11101 tatgggccag ctattcgcct ctttcccgag caggtttggc gtctcttgtc tgccattttt
    11161 gttcatattg ggtgggaaca tttcattgtt aatatgcttt cactttatta tcttggaagg
    11221 caggtagagg agattttcgg ctctaagcag ttcttttttc tctatctctt atcaggaatg
    11281 atgggcaatc tctttgtttt tgtatttagt cctaaatcct tagcagcagg cgcctctacc
    11341 tctctttatg ggctatttgc cgcgattatt gttcttcgct atgcaactcg caatccttat
    11401 atccaacagc tagggcaatc ctatctgaca ctttttgtgg ttaacattat tggaagtgtt
    11461 ctgattccag gaatcagcct agcaggccat atcggtggtg cagttggtgg cgcatttcta
    11521 gcagttatct ttccagttag aggagaaaaa cggatgtata acaccagcca gagattagga
    11581 gcggtagtct tgttcgtagg actcgccatt ttgcttttct acaagggaat gggaatgtga
    11641 cgactaatac tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gttgctcaaa
    11701 gcactgcttt gaggttgtag atagaactga cgaagtcagc tcaaaacatg gttttgaggt
    11761 tgtagatgaa actgacgaag tcagtaacca tatatacggt aaggcgacgc tgacgtggtt
    11821 tgaatttgat tttcgaagag tataatatgt aaacttgaat aagaaaaaag ctacttaaaa
    11881 aatgagtagc ttttaatgtg ttttggaacc attcgaaaca acacagctct aaaatagtta
    11941 ttagcgttgt ggaggttctg caatgcctcc cccagtgttt ccaagataat tccaattttc
    12001 gtcaaacaca tctccattgc tctcattgtc gtaagtataa cttacatgtc catcagcacc
    12061 aatattctta tattttttat agtagccatt atttactccg ctgttggaat tgctagatga
    12121 atattgttct gatgatccac catttgttga actatctcca gaaccagaat aactttgact
    12181 tccataatta ttcgaatatc cattagtttg ttcagatgaa ctataatcta catttgaatt
    12241 ggaagatcca ttataagact cattagaagc accactagaa gaattacttt gactagaaga
    12301 ttcctttgct ttttcagcag ctttttcttc ttctttcttc aaaagttcga tttgtttttg
    12361 atatttatca acaagatcat ttagagattt aagagtttct tccaaattct cttgtttaaa
    12421 agtttcatca acttttttga taaaatcaat ttgttttgta atttctttca catttgtttc
    12481 aagagttgct ttatctttaa acttctcatc agaatcttta acatcataag ccaaaccttt
    12541 ttgcaaatga aaatctacaa ttgctttaga tgattctttg actttgttat taagatagtc
    12601 tttacctgca tcggttttaa gtgaagtttc agatagttct tttaatttag aaatagattc
    12661 atctgaagat gcatcaaatg attcaaatag tttatcaact tgttctttgt ctgatttgct
    12721 atctttttct aattgtacaa tttttgcttg ttgttctgct tgttgttggt tatatgaata
    12781 ccatccaaac cctaatacca atacaacacc aactgcaact gatgaaatga ttactttttt
    12841 attgttttcg ataaattcta caaatttgtt ctccataatc ttttactttg atagtgtccg
    12901 caattacttt aaaattaaaa ttacacctat ctttctccct tattatattt ttattaatag
    12961 cttccacaaa attaaacaac ttatgttcgg ctcggttgat ttaatttaac catgactact
    13021 ccaacagtta agtcaaattt aaaattattt attattttgg aaccattaga aacaacatag
    13081 caaagttaaa ataaggcttt gtccgtacac aacttgaaaa agtgcgcacc gattcggtgc
    13141 ttttttgttt tactatacta atttattcta ctcttatttt aatgaaaaaa caaatacaag
    13201 tatagcgttt tcattagttt ttattaaata ggtagattca agtagagaat ttacttaatt
    13261 tatgtgtggc taatctttat ataaatgatt ttgttattcc ttctcagtca attcttttcc
    13321 aagttggatg aggtaattct tcaaatcatc tttgacttgt ggatgtttga gggcgtagtc
    13381 gatggatgtt ttcatgaagc caaacttgtc tccgacatcg taacgagccc ctttgaactc
    13441 acgagcaaat acacgttgtg ttttattgag ggtgtcgatt gcatctgtca gctgaatttc
    13501 atttcctgca cctggagctt gcttttcgag aatctcaaaa atttcaggcg tgaggaggta
    13561 gcgtccgata atagcaaggt cgctaggagc gtcctctgga gctggttttt caacaaaggt
    13621 ttcaacactg taaagaccat cttttccttc gccttgcgga gcaataaccc cgtaagcaga
    13681 tacttcgtca tgagggactg gcatgacagc gatagtagac gcgtgggtac gctcgtagtc
    13741 atccatgagt tgtttggtaa gtggaacagc cttttcgtct gtgatatcca tcaagtcatc
    13801 accaagcata acgacaaaag gttcatttcc gacgaaagcc ttggcttgca aaacagcatc
    13861 tccgagaccg cgtggatgag tttggcggat aaaatgcaga cgcatgccag ttgtttcatc
    13921 aactagcttc aaaagatctg ttttcccttt ttctttgagg ttatattcca attcgaagtt
    13981 tgaatcaaag tggtcctcaa tagaacgttt tgatttacca gtgacaacta gaatatcttc
    14041 aatacctgat ttgagagctt cttccacgat aaactggata gttggtttgt ctacgattgg
    14101 caacatttct ttggcaaggg ccttggttgc tggtaaaaat cgagttccta gtccagcagc
    14161 agggatgact gcctttctaa cttttgatgt cataaaaatc ctttctatag agggttaaga
    14221 ccactcattt tctgctttaa attcattgtt catgatgtca taaatggcat ctttgatatt
    14281 ggttccgtga taaataactt ggtaaatagc ctgtgtaatg ggcatataga ctccaagttc
    14341 ttgggctagt tcataggctg ctcgagtcgt tgaaattcct tcgattacca tgcccatatt
    14401 agcttctata tcagctaggg attctcctcg tccgagagca tttccagctc tccagttacg
    14461 agagtggatg gaagttcccg ttacgatcaa atctcccaca ccagataagc cgctataggt
    14521 caatggactg gccccgagtg ctacccctag gcgggtgatt tctgctaaac ctcgagcgat
    14581 gatggctgcc ttagcattat caccaaatcc aagaccatgt aaagctccag caccgacagc
    14641 aataatattt ttaagagcac cagcagtttc aaccccgata acatccgtat tggtataaag
    14701 tcggaagtag tgattactaa atagcttctg aacgtattga gctgtttgta aatctttaga
    14761 agcagcagtt attaaagtta ggtcacgcac aatggtctct tctgcatgac taggccctga
    14821 aacaacgacg atatcactac ggagatgttc aggaatttct tcttcaagaa tggttgataa
    14881 tcgtttatgg ctatcaggtt ctaatccctt tgatgcgtgc atgatgataa ccttatggtc
    14941 caaggtttgt gcaacttgct gggcaacaag tcgtgtcact tttgttggga caacaaacaa
    15001 aatcgcatcc acatctttca atgtttctgc taagtcggtg taggcaatga tattttcgtc
    15061 tagaacgaca tctttaaagt agtgcttatt agtatggtgt gtattaattt cattgatttg
    15121 ctcgggaaga tttccccaaa tacgtacctc gtgtccattg tcatttaaga cttgtgaaag
    15181 ggcggttccc caagaaccag gccccaagac ggcgacggtt tgtttttcca tgatttcctc
    15241 cttgatagag ttctttctct tattctatca tattctaggg gattttgcac ttgcattact
    15301 ggggtatggt ggaaaaatac acaaaaaccg agacgaaggg ataaactctt agtctttagt
    15361 taaagtgaga agaaatctga tagatagttt gattcagtat atgcttataa tagaggtaaa
    15421 caactcagga ggttcttgta ggttgcgaga gtttggcgaa aaaattaaaa gattacgttt
    15481 ggctaaaaaa atcagtcgtt cagaattttg tggtgatgag tctgaattaa gtatccgtca
    15541 attaattaga attgaaaatg gagaatccag accaacacta acaaagttaa aatatatcgc
    15601 tgaacgtttg ggggttgagg attacaagtt gatgccaagt tatatagagt tggataagga
    15661 atacctagaa ttgaagtatt ttttgatgag gactcctaca tacgaagatg aaactatcgc
    15721 ccaaaagaaa gagagtgttt tgataagatt tttgaagagt attatgatag gctacctgag
    15781 gaagaaagat ttatcatccc aaattattca tatctggcac taacgaacta cacagttcaa
    15841 aaattaccag aaaagctagt tgaaatactg tccttctggt gattttgctt aatttctgat
    15901 gttcgagaca taattgagga gatttgtctt gattttttcc taaaaaaggg cagacttctc
    15961 ccttggtttg atgctcgatt tttaaaataa ggtgacttat tctgttaggc atgttttccc
    16021 ctgccctcta gctctatatg gaacagggag tatcagattt atctggcaga ttgtatcaaa
    16081 taaggcttga aactgttttg aataggcgta tagacttgag aatttgagaa tatgtcgtct
    16141 agcagtagag acatattttc cggcaatatg aaggaagaga cgtcgaaaac gcttgatagt
    16201 caaggacttt acttcatcac cagctagctg ttttaaaaag aggtagagat tataagccag
    16261 acagcctatc atcatacgta cttcattctt aatcatggtc gaactatctg tcttatcccc
    16321 aaagaatcct gctttccttt ctttgataaa gttttcagca ttccctcgtt cacgatagaa
    16381 ttgaaacagc tcctcactat ctacactgct taaattggtc aaatgaactt ttttacaacc
    16441 ataaaaaaga gcacttaatc gtactcttct cttttaagga ttagttgaat taattcaaat
    16501 ccactagttc tcctgtttct aggtagacta ggcgttcaca aatgttagca atgtaatcag
    16561 cgaagcgttc cagatgccct atgatataaa ggtattgtgt tccattggga attgaggttt
    16621 cttggtcttt cataagtcca atgatttcct ttgataaggc ataataatat tggtcaatct
    16681 gttcatcttt ttgagcaata ctaatagctt ttgaggcttg gtgcaaagga aaggcaacca
    16741 ataaatcgga tagcatgctg agggataatt tacccatttg gtgtaactgt tcttcgtcag
    16801 gggctagttg attttctttt agttgcaaaa cagctttagc aatgcctgcc atatggtctc
    16861 ccatacgttc aaggtctgaa caagaagaca tgatgctaat cacaaatcga aggtcagaca
    16921 cttgtggctg ctgcaaggcc aacaaacggg cacaggtcaa ttcgatagcg ctttgacctt
    16981 ggttgatagc atgatcctta ttgataatta gctctgccat ctccttgtct ttggaggcta
    17041 aggccagtaa ggtttttgaa gctgtttcaa ggacaagttg ccctagtcct aaaaaggatt
    17101 gttctaattc atgcaattct aagtcaaatt gatttctcat aggtttttcc ttccttatcc
    17161 gaaccgtcct gaaatatagt cttctgtgcg ctgatctttt ggattggtaa acacgtcaac
    17221 ggtgtctcca aattcgcaaa tttctcctgt taagaaaaaa gcagttttat ctgaaatacg
    17281 tgaagcttgt tgcatgttat gggtaacaat gataatcgta taatcctttt ttagttgctg
    17341 aatgaggtct tcaattttta aagtggagat agggtctaag gctgaagtcg gctcatccat
    17401 taacagaaca tcaggttcta ctgctaaagc tcgcgcaatg caaaggcgtt gctgctgacc
    17461 gcctgataag gacatggcac tctttttaag attatctttg acttcgtccc aaatggctgc
    17521 cccttttaaa gatttttcca ctaaggcatc taattgtttt ttgtctcgaa taccatgtgt
    17581 ccttgggcca taagccacgt tatcatagat agacatggca aagggattag gctgttgaaa
    17641 aaccatccct acacgcttgc gtagctgatt aaggttgaat ttgctactat aaatatcttg
    17701 ctcatctaag aggacttggc cttcaatatg gcaagaagga accaaatcgt tcatccgatt
    17761 aagggttttt agaaaagttg atttgccaca accagatggg cctatcaagg cagtaatctg
    17821 tctttctggt aattgaatcg aaatattttt taaggcttga aaatccccgt aaaataagtc
    17881 taggtgtctg actgaaaatg ttcccatact aggaagctcc tttcacaagt ttccgagata
    17941 ataagcttga tagagtattt atcattaaaa cagtaataat caaaatcacg ccggtagcat
    18001 aggcttcatt gacatgtagc ccctcacttg acagcatata catatgtagg gctagagaac
    18061 ggcctgaaga catgagacta cttggcgtat tggtagaggt acctaatgta tacatgaggg
    18121 cagctgtttc accaacgata cggccaatag ctagtatcac tccagctaaa atacctggca
    18181 tggcaactgg tagaacaatt ctaaaaacag tccgtaactt acctgcccca agtccataac
    18241 ttgcttgacg catactatca ctaacagata aaagggcttc ttctgttgag cgaataatga
    18301 ctggcaacac catgataact gaggttaaga ttcctgataa cagagagtat tgaaaaccta
    18361 agaagactac aaagaagagc atgccaaaca gaccaaaaac aatggaagga atcccagata
    18421 aggtatctga ggccaatcgc atgattttaa cacaaaggga atcttttttt gtatattcca
    18481 caagataaaa accagcaaaa atccctatgg gcaaggctaa aagaagagca ccaaagacca
    18541 gaataacggt ggaaataatc gctggcataa gggaaatgtt ctcagaagta taagtccaag
    18601 aaaagaggga tagacttaga tgaggtaagc ctttgatgag gataaaacca atgattaaaa
    18661 agagagagcc aaaggttaaa gctgaaaaac aataaacgag aagttttagc aggtatttac
    18721 tcataagatg attttccttt caagtaggca aagtaggcat taatcaagag aataaggaaa
    18781 aagagaactg ctgaggttgc aataagggct tccctatgct gacctgatgc gtaagccatt
    18841 tccagaacaa tattggttgt taaggttctg gttcctgaaa agagtccact tggaataatc
    18901 ggctggttgc ctgccaccaa aataactgcc atggtttcac ctactgcgcg accgattcct
    18961 aaaataactg ctgataaaat accagatctc gcagctggca agatgacact aaaaatactc
    19021 cgttcatgac tagctcctag agccaagcta ccagaataat acgttttggg aactgttcgg
    19081 atagcagatt ctgacaaact gataatggtt ggcaaaatca ttattcctaa tagtaacgaa
    19141 gcggttagga cactcatgcc atttcctaaa aagcttctaa tccaaggcac caataattgt
    19201 aggccgaaaa aaccataaac aatagatgga atggctgcca tcaagttgat agctgatttt
    19261 aagaagccat agacgggctt tggacaataa taaaccataa acaccgatgt caagatgcct
    19321 gttggcaccc caatcacaat cgctcctaag gtaattaata aggaaccaac gatcattggt
    19381 aaaataccat agcttgccgg aatgttcgtt ggcgaccaat cactgcctaa taaaaaacgg
    19441 gcaaagccgt agttagctat gaaaggtaag ccattactaa aaataaagaa acagattagc
    19501 aaaatagcta caacagctac tgttgcactc atgaaaaaaa ttgccctaaa aactgcttct
    19561 ttgaaggctt gttttgtcac atcttgtcct ttctagtgaa gaaagtaagg gagatacgac
    19621 acctccctac ttgccttctt tatcttattg tacgatgaaa cgtctgcatc tctttagaga
    19681 tttatggagc aaacatttta tttaatcttg tcccaggtgg ttaatttgcc actaaaaacg
    19741 tctgcaagtt cagccatact gacttggctt gccttattgt cattattgac cacaacagca
    19801 ataccgtcta aagcaatagc atcatgggtg agactcttac cttcttcagg agttaattcc
    19861 ctagaaacca taccaatatc agcggttttc tccttaacag cggtaatacc tgctgaagac
    19921 ccattagagg taatatcaat cgtaacttct ggattttctt ttttataagc ttctgctaat
    19981 ttttccatta aagaagatac tgaagtggaa cctacaacag acaacttgcc tgataagtgt
    20041 tggcttgtat attctgtggt ttcggtttta gcttcaataa atttattatc agtgaccact
    20101 tgttgacctt gtttggagtg gataaagctg ataaaatctt gacctagctt ggaaagatta
    20161 gaagaccaaa caatgttgaa gggacgttga agagggtatt caccatctaa aactgtgtct
    20221 cgactagcct tgacaccatc aatctctaaa gccttgacag atttcgttaa agatcccaag
    20281 gagatgtagc cgatagcatt agcattccct tgaactgctg agagaacacc ttctgtacta
    20341 ttttgaatca cagctgtttt ggcagtgttg tcaatttttt tatcaccgtc ttttttgaga
    20401 atccctgtga tttctgtgaa ggcaccccgt gttccagagc cattttctcg tgaaatcacc
    20461 tcaatcgttc ctgaagctga ctgtttggaa gcagctgact gattgccaca ggcaacaagc
    20521 ccaaatcctg ataagccaat ggctgcaaga gtaagcattt ttttgaattt cataataatc
    20581 acctttatct ctatgtattt ttcttgtgta ggcttactac atttatagtc taacaagtct
    20641 ttgtaaaggt ttatccctga ttcatgtaaa gattgtgtaa agaatcaaaa aaagccactt
    20701 ttgaaaaatg gctgctccta aaaatagctt taaaaattat tagtcctgtg cgaaagattg
    20761 gttaggaaga aaaatcgtga agcaactgcc tctgccaagc tgactcgtca ccgtgacttg
    20821 gccacctaat aattgactga gttctttgac aatggcaagg ccaagaccag tgccaccagt
    20881 ttgtctgctt cgacctttat taactcggta aaaacgttca aaaatacgat cctgctctaa
    20941 ttgactaata ccaatccctg tatctgatac agaaatctta atgccttcgt tcaccttttg
    21001 ggtcttgacc tcaatttttc ccccttgttc agtgtaacgg atggcattgg ataaaagatt
    21061 gagtaagatt tgggaaagta attgactatc tgatacgagg gtgacatcat ctggcacctg
    21121 cacctttagc tgtaaatcct tcttcttgag ctgaggttgc aagctttgag tcaaatcctg
    21181 tacaaattct gccaaagaaa gggtcgtcca ttgtataggc atttgttgag ccttagataa
    21241 ggtaagaaga tgctcaacaa tatgctcaag acgcaagctt tctttgtaaa taatgtctag
    21301 aaagtcatcc ttgagcgctt cttcttcagc tgacatcccc ttaatggttt cagcaaagcc
    21361 cttaatcgaa gtaactggtg tcctcaattc atgggaggca tttgagacaa aggctaaatt
    21421 taacttttca taagttctaa tcgttgttaa atcatatagc aagacgagca cagcttccac
    21481 agattgggtg gggctaaaaa cgggaactgc tgtcacttct aaaatcaagt caccctcatg
    21541 aaacccactt acttcttgtt ttaaccttgt tttttgatca aaggcttggt gaactaaatt
    21601 tcgaatatcc atccgtttga ggtcatcaag tgaacttatg tcgccgtcca catcgggaaa
    21661 ataatgaggc agagagcgac tggataataa catctgacct tgagcggaaa ctaaaaacgt
    21721 ccccatggtt aggtgcgaca gaagaacctc cattgtttcg gctaggtcct tgtattgctg
    21781 atcctgttgg gagactttgg tttttaggcc agacacatac tgagccaaag actttaagtc
    21841 ttcttgccct ttttctaaaa agtattcact actggtcaag agaggttggt gcaaggtctc
    21901 aaaagcaact tcccatttcc aaaggcaaaa gagccagtag ccaccttgtc ccaaagaaag
    21961 ggctagaaga aagagaccga tgcctttact gatccaagtt aatgccatcc ctgcaatcag
    22021 aatgaggcta acacttagat tgactagcca aaattgaagg tagcgtttca tctataactc
    22081 cttgaactta taaccataac cccgaatggt tcgaataaat tgaggggctt taggattgtc
    22141 ttcaattttt tccctcaact taccaatatg aacgtccacc aaacgtgttt cctgcccaaa
    22201 gtcatacccc cagatacgtt ccaaaagacg ctctctagtt agtgtcatgt tgggatgttt
    22261 cataagatag agcaagagtt caaattcttt tggggtcaaa ctcagtaact tattcgcctt
    22321 gtagacttca tgacgctcag ggtatacttt caaggtccca aatagccaag aatcgtcagc
    22381 gatattatct gaatcatctc cttcttgttc tcctttagtt cgcctgagga cagccttgac
    22441 acgcgccagc aattctctag ggctaaaagg cttggtcagg tagtcatcag cccctaattc
    22501 caaggccaaa accttatcaa attcatcact tttcgcagaa accatcataa ttggagtttt
    22561 gacgcctttg gctctcagtc gcttacaaac ttccatgcca tctaattgtg gtaacatgat
    22621 atcaagcaag ataaaatcaa agggttctgt ttctgccaaa gctaaggcct tccgtccatt
    22681 tgttaccaat tgagtagaaa agccttcctt acttaaatgg tagtcaagca atttcagaat
    22741 gtgttcttca tcatccacta ataagacttg ttttgtcatc tattatctcc tattggtaac
    22801 attataacac aattatcaga aatcctaaca ttgctaaatt agattaaatt tgcttatcaa
    22861 gactagtatc tggtcaaatg ctcaatcatc tccttgtgct ctggataggt cgccagtaga
    22921 tctgcccttt caaataattc aaaatcctca aattcaaaac caggagcaac aagacaagaa
    22981 accagagcat aatccttatc aactgttgat ccccaaatag tgctcttagg aacacagtag
    23041 tgaagttgtt gccctttgga tatgtccagg cctaaagtga ctgcttcgta gtgaccatct
    23101 gctgtaatca tgtgaacagt aagtggggat cctgcatgaa aataccagat ttcatctgct
    23161 gtcaatcggt gaaaatgtga aggattcgtt tcttctaata agaaataaat actggtataa
    23221 agcgcccttc ccttaccagc aaggtttata gtgtctgaag ctttttttgt ttgtctaaaa
    23281 tagccacctt caacatgggg agctaactct agagttctta tcaagtcttc tttatccatc
    23341 ggggccaatg ggttgaagta actcttgttc aaagtggtgt tacgatttca agaactcctc
    23401 tcagttctga ggacacggta atgattgatg cgacggaagt aaaaatcaat cgccctaaaa
    23461 aaagaattag cgaatgattt tggtaaaaag aaatt
//
LOCUS       DAVAGB010000031        23049 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVAGB010000031 DAVAGB010000000
VERSION     DAVAGB010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23049
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.031"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(197..601)
                     /locus_tag="VQO19_001398"
     CDS             complement(197..601)
                     /locus_tag="VQO19_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET1349648.1"
                     /translation="MKTFLAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQLIAYIGAVLCLIIMLLLMWGLKYYKK"
     gene            complement(598..762)
                     /locus_tag="VQO19_001399"
     CDS             complement(598..762)
                     /locus_tag="VQO19_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349649.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            complement(1059..1178)
                     /locus_tag="VQO19_001400"
     CDS             complement(1059..1178)
                     /locus_tag="VQO19_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET1349650.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDNLIRKIFSKFPKKDTDSTP"
     gene            complement(1181..1411)
                     /gene="blpU"
                     /locus_tag="VQO19_001401"
     CDS             complement(1181..1411)
                     /gene="blpU"
                     /locus_tag="VQO19_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET1349651.1"
                     /translation="MNTKMMSQFSVMDNEMLARVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            1692..3739
                     /locus_tag="VQO19_001402"
                     /pseudo
     CDS             1692..3739
                     /locus_tag="VQO19_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
     gene            3750..5111
                     /locus_tag="VQO19_001403"
     CDS             3750..5111
                     /locus_tag="VQO19_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HET1349652.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ETQLQRLEKQKEGLGILKQSLEKATDLFSSEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDAIVNKRARLPTGNPHQSILNRY
                     LIASQEQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPIITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            5168..5323
                     /gene="blpC"
                     /locus_tag="VQO19_001404"
     CDS             5168..5323
                     /gene="blpC"
                     /locus_tag="VQO19_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HET1349653.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDILYSLNIIKHNNTKG
                     LHHPIQL"
     gene            complement(5368..6708)
                     /locus_tag="VQO19_001405"
     CDS             complement(5368..6708)
                     /locus_tag="VQO19_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET1349654.1"
                     /translation="MNIVWILLHTLITNGLEIVIFFKVDGINLTFERIFKAFLLKILL
                     VFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYALFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRREILDTGFQK
                     SLTKINWIMGAYYLVIQSLSYFEYEQGIQSTTVRHLILVFYLLFFMGVIKKLDTYLKD
                     KLHDRLDQEQVLRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYDLVLKDSSKKLQDNKYDLGRLVNVRDRALKSLLAGKFIKAREKDIVFNVEVPEEI
                     QVEGMRLLDFLTIVSILCDNAIEASAEAGQPHVSIAFLKSGAQETFIIENSIKEEGID
                     ISEIFSFGVSSKGEERGVGLYTVMKIVESYPNASLNTTCQDQVFRQVLTMIPTE"
     gene            complement(6722..7459)
                     /locus_tag="VQO19_001406"
     CDS             complement(6722..7459)
                     /locus_tag="VQO19_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET1349655.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(7464..7802)
                     /locus_tag="VQO19_001407"
     CDS             complement(7464..7802)
                     /locus_tag="VQO19_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET1349656.1"
                     /translation="MKHMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEKASFNM
                     VQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            8078..8407
                     /locus_tag="VQO19_001408"
     CDS             8078..8407
                     /locus_tag="VQO19_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET1349657.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(8575..9624)
                     /locus_tag="VQO19_001409"
     CDS             complement(8575..9624)
                     /locus_tag="VQO19_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET1349658.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     QVLYLPYQVKRQMQD"
     gene            complement(9621..10352)
                     /locus_tag="VQO19_001410"
     CDS             complement(9621..10352)
                     /locus_tag="VQO19_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1349659.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            10420..10830
                     /locus_tag="VQO19_001411"
     CDS             10420..10830
                     /locus_tag="VQO19_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET1349660.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            10840..11127
                     /locus_tag="VQO19_001412"
     CDS             10840..11127
                     /locus_tag="VQO19_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349661.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(11449..12585)
                     /gene="dnaJ"
                     /locus_tag="VQO19_001413"
     CDS             complement(11449..12585)
                     /gene="dnaJ"
                     /locus_tag="VQO19_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HET1349662.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGDGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGQGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(12987..13343)
                     /locus_tag="VQO19_001414"
     CDS             complement(12987..13343)
                     /locus_tag="VQO19_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HET1349663.1"
                     /translation="MSVLDDEYLKNTRKVYNDFCNQADNYEAAKGFIDNIPVECLTIY
                     REIILAEHDSCVKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(13345..15168)
                     /gene="dnaK"
                     /locus_tag="VQO19_001415"
     CDS             complement(13345..15168)
                     /gene="dnaK"
                     /locus_tag="VQO19_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HET1349664.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(15648..16172)
                     /gene="grpE"
                     /locus_tag="VQO19_001416"
     CDS             complement(15648..16172)
                     /gene="grpE"
                     /locus_tag="VQO19_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HET1349665.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSKLDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(16199..17233)
                     /gene="hrcA"
                     /locus_tag="VQO19_001417"
     CDS             complement(16199..17233)
                     /gene="hrcA"
                     /locus_tag="VQO19_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HET1349666.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(17397..17834)
                     /locus_tag="VQO19_001418"
     CDS             complement(17397..17834)
                     /locus_tag="VQO19_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HET1349667.1"
                     /translation="MHLKGWRYRTSRFGLFYFDQCQPDDVIYRIYDSRFLKKYKHELQ
                     DFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMSKGLKWEVMRSRLRSCTTTFLGGLV
                     VCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFRLKRKYRVDE"
     gene            18514..20847
                     /locus_tag="VQO19_001419"
     CDS             18514..20847
                     /locus_tag="VQO19_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET1349668.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKVIDYFSSATQIGMTATPKETKN
                     ASNMEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVGGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTSN"
     gene            20894..22357
                     /locus_tag="VQO19_001420"
     CDS             20894..22357
                     /locus_tag="VQO19_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET1349669.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSIM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            22357..>23049
                     /locus_tag="VQO19_001421"
     CDS             22357..>23049
                     /locus_tag="VQO19_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET1349670.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILI"
BASE COUNT         7395 a         4638 c         4192 g         6824 t
ORIGIN      
        1 gaactatagt aaaatgaaat aagaacagga taaatcgatc aggacagtca aatcgatttc
       61 taacaatgtt ttagaagtag aggcgtacta ttctagtttc aatatactat accatatttt
      121 gtttcgcagg gaatctatta taaaagggta agtattgcaa aaacacttac ccttttcttt
      181 tatacttcat taagctctac tttttataat acttcaagcc ccacatgagc agaagcatga
      241 tgattaagca gagaacagcg ccaatataag cgattagttg ttgataagat tctcctgctg
      301 tgatacctct atacaaacaa ataatagaca taaaacctgt caagccgata aacataagtt
      361 gattggttct aggactaacc aaatcatcat cttcaaactc tcttatcctc atttccctag
      421 tgagataaac agtaaccaaa atagaagcca agttaataac tactaaaaga aattggaaaa
      481 ctacggaaaa atttaaaaac tgacgagata gaaatagata agtagaaaca agcaagggca
      541 actgacctaa gaacaatctc gcaaggaaga tgttccgttt tttagcaaga aaagttttca
      601 tttcttttct cctttctttt tattgatagc aaaatagatc ataactgcaa tcacataggc
      661 tatggtataa aatagctgat accaagcact ctccctaagc ggatatagaa agatggacat
      721 gattagatac agaacgaaaa taatcagtat ttttttcttc ataagatttc ctcctaaatg
      781 tgcgatttat cttagttgag caagaacatt tacactgcta gtatagcact tattttgacc
      841 ttggatcact caaatcataa atggtcatca aaacctcttg aattgtaaaa attaaaaaag
      901 caagcatgaa aaacatactt tcctctttat attgtattga taccaacttg tttgtagact
      961 tttcatcctg ctatcacata tcattttgac aggcgaaaca aaattaaaga aactcccctg
     1021 taaattaagc tagcaaatac aggggagaaa tttatttttt agggggtact atctgtatcc
     1081 tttttgggaa attttgaaaa tatttttcta attaaattat ccatataagg accaaatata
     1141 ccaactacta aaccaataat aaaactttta aaatccataa ttaccaccaa catgttgctg
     1201 cataggctac acctccaagt atagctccac ccgcagcacc agttgctgca ccttgccatg
     1261 ttcctgtttt aatgcctagt tgaagacctc ttgctgctcc tcctccaaca cctgctttgg
     1321 caaaatctcc ccaattgcat ccgccacctt caacacgagc aagcatttca ttatccataa
     1381 cagaaaattg tgacatcatt tttgtattca tgacaaatac tcctttttta tttttaattt
     1441 ttgtcttgtt gcaactttga caagtttagt atatcatcgt tttttaaaat ttttcatcca
     1501 gatcttgaat agtcatcgaa acgtcttgaa ttagcttttc atttgaaacc acctctaaat
     1561 tttttaaaaa aagataattt ctaattattt tttaccattc aggaagtttc aatgactatt
     1621 caagatttaa taaaatatga acttattttt atggcataat atacctatct actatatgaa
     1681 aggaattgcc aatgacttct tataaacgta catttgttcc tcaaatagat gcgagagact
     1741 gcggtgttgc tgccttagcc tcgattgcta aattctatgg ttcagatttt tctctagctc
     1801 acttgagaga acttgcaaag accaataaag aagggacgac tgctcttggc attgtaaaag
     1861 ccgctgatga aatgggcttt gaaacaagac ctgttcaagc agataaaacg ctctttgaca
     1921 tgagtgatgt cccctatcca tttatcgttc acgttaacaa agaaggaaaa ctccaacatt
     1981 actatgttgt ctatcaaaca aagaaagact atctgattat tggtgatcct gacccttcta
     2041 taaaaatcac taaaatgtca aaagaacgct ttttctctga atggactgga gtagctattt
     2101 ttctagctcc caaacccagc tatcaacccc ataaagataa aaagaatggt ctactaagct
     2161 tccttcctct gattttcaaa caaaaatctc tcattgctta cattgttctc tcaagcttat
     2221 tggtcactat tatcaatatc ggtggttctt attatctcca aggaatctta gatgaataca
     2281 tcccaaatca gatgaaatca actttaggaa tcatctcagt tggtctggtt atcacctata
     2341 tcctccaaca agtcatgagc ttctccagaa attaagcatt gatgtgattt tatcctatat
     2401 tcgccatatt tttgaacttc ccatgtcttt ctttgcgaca cgtcgtacag gagaaatcat
     2461 ttcacggttc acagatgcta actctattat agatgccttg gcttctaccc ttctttctct
     2521 tatttccatt cctatataca tgttcatcat cttttctttt atgaaacctt tcgaaaaaat
     2581 gaaccatgat gtcatgcaaa gtaattctat ggttagctct gccattatca aagatatcaa
     2641 cgggattgaa actataaagt cgctcacgag tgaagaaaat cgctatcaaa atatagacag
     2701 cgaatttgta gattatttgg aaaaatcctt taagctcagt aaatattcta ttttacaaac
     2761 gagtttaaag cagggaacaa aattagttct gaatatcctt atcctatggt ttggcgctca
     2821 attagtcatg tcaagtaaaa tttctatcgg tcagctgatt acctttaaca cacttttttc
     2881 ttactttaca actcctatgg aaaatattat caacctccaa accaaactcc aatctgcgaa
     2941 gatcgctaat aaccgtttga acgaagtcta tctagtcgaa tctgaatttc aagttcaaga
     3001 aaaccctgtt cattcacatt ttttgatggg cgatattgaa tttgatgacc tttcttataa
     3061 gtatgttttt ggacgagata ccttaacaga tattaatctc acgattaaac aaggagataa
     3121 ggttagccta gttggagtta gtggttctgg taaaacaact ttagccaaaa tgattgtcaa
     3181 tttctttgaa ccctacaaag ggcatatttc catcaatcat caggatatta aaaacattga
     3241 taaaaaagtc ttgcgccgtc atattaatta cctaccccaa caagcctata tctttaatgg
     3301 ctctattttg gaaaacttaa ccttgggcgg taatcatatg attagtcaag aagatattct
     3361 aaaagcttgt gaagtagctg aaatccgtca agacattgaa agaatgccta tgggctatca
     3421 aactcagctc tctgatggag ctggtctatc aggaggacag aagcaacgaa tcgccctcgc
     3481 tcgtgctctt ttaactaaat ctcctgtttt aatactagat gaagctacta gcggtcttga
     3541 tgtcttgact gagaaaaagg ttatagataa tcttatgtcc ctaactgata aaaccattct
     3601 ctttgtagcc catcgtctca gtatagccga acgaactaac cgtgtcattg ttcttgacca
     3661 ggggaaaatc attgaagttg gtagtcacca agagttaatg caggcgcaag gcttctacca
     3721 tcatctattc aataaataag gagaatgtca tgaatcctaa tctttttaga agcgtcgagt
     3781 tttatcagag acgttaccat aactatgcga cagtgttaat tatacctctt tcattactgt
     3841 ttactttcat cttgattttc tcccttgttg ccacaaaaga aattactgtt acttcccaag
     3901 gagaaatcgc ccctacaagt gtcattgcat ctattcagtc gaccagtgat aatcctatcc
     3961 ttgctaatca tttagtggca aatcaagtag ttgagaaagg tgacttactc atcaaatact
     4021 ctgaaacaat ggaagagagt cagaaaactg ccttagaaac tcaattacaa aggcttgaga
     4081 agcaaaaaga aggacttgga atcttgaaac aaagcttaga aaaagcgact gatctttttt
     4141 ctagcgagga tgagtttggc taccataata cctttatgaa ttttactaaa caatcccatg
     4201 atattgaact gggtatctca aagactaaca ctgaagtttc aaatcaagct aatcttacca
     4261 atagcagttc atcagccatc gaacaagaaa ttacaaaagt tcaacaacaa attggagaat
     4321 atcaagagct gagagatgct atcgtaaata aaagagctcg cttaccaact ggcaatccgc
     4381 accagtcaat tttaaatcgt tatcttatag cctctcaaga acaaacacaa ggaacggcag
     4441 aggagccatt tttatctcaa attaatcaaa gtattgcagg tctggaatca tctatcgcaa
     4501 gcctcaaaat tcagcaagct ggcatcggaa gtgtagcaac ttatgataat agtttagcaa
     4561 ccaaaattga agtactccgc actcagtttt tacaaacagc ctctcagcaa caactaaccg
     4621 tggagaatca attaacagaa ttaaaagtac aactagatca agcgacacag cgcttagaaa
     4681 acaatacctt aaccgctcca agtaaaggta tcgttcatct gaacagcgaa tttgaaggta
     4741 aaaatagaat tccaactggt acagaaattg ctcaaatatt ccctatcatc acagatacaa
     4801 gagaagtact aatcacttac tacgtatctt ctgactatct acctctacta gataaaggac
     4861 aaactgtaag attaaaactg gagaagattg gaaatcacgg caccaccatc atcggccaac
     4921 ttcagacaat tgatcaaact cctaccagaa cagagcaagg taatctcttt aaattaaccg
     4981 ctcttgcaaa actatctaat gaggatagta aactcatcca atatggctta caaggtcgcg
     5041 tcactagtgt aactgcaaag aaaacatatt ttgattattt caaagataaa attttaaccc
     5101 attctgatta attttcagat aacactctat aactatttat tatcttatca aaaaggagaa
     5161 tcataacatg gataagaaac aaaacctaac ttcatttcaa gaactaacaa ctaccgaact
     5221 caaccaaatt acaggtggag gactgtggga agatatctta tacagcctta atataattaa
     5281 gcataacaat acgaaaggac ttcatcatcc aatacaacta taaaaaataa gaccgagtaa
     5341 caagaactct cggtcttatt tttttcatca ttctgtaggt atcatagtaa gcacctgacg
     5401 aaagacttga tcttgacagg tagtatttaa actggcattg ggataacttt ccacaatctt
     5461 cataacggta tagagaccga cacctctctc ctccccttta gaactaactc caaaggagaa
     5521 gatttcagaa atatcgatgc cctcttcttt gatggaattt tcgatgatga aggtctcctg
     5581 tgctccactt tttaaaaagg caattgaaac atgaggttga ccggcctctg cactcgcttc
     5641 aatagcatta tcacaaagga tagacacaat ggttagaaaa tcaagcagtc tcatcccctc
     5701 aacctgaatc tcttcaggaa cttcgacatt aaagacaatg tccttttctc tagcttttat
     5761 aaattttcca gctaggagac ttttgagggc acgatcccga acattcacca atcggcccag
     5821 gtcatattta ttgtcctgca attttttact agaatccttt aagaccaagt catagacctc
     5881 ttttatctgc tccatatcct cctcttcaat acccagacgt aaacttgtca agaggttggt
     5941 gtagtcatgg cgaaaactcc ttacttcctt gtaaagttcc tctatatgcc gactatagcg
     6001 ttccatatct ctatagcgca agacctgctc ttggtccagt ctatcatgga gtttgtcctt
     6061 caaataggta tccaatttct tgataacccc cataaaaaat aggaggtaga acactaggat
     6121 gagatggcga acagtcgttg attgaatacc ttgctcatat tcaaagtaag acagactttg
     6181 tatcaccaaa tagtaagccc ccattatcca gttaatctta gtcagggact tttgaaaacc
     6241 tgtatctaga atctcccttc tcaaactagt aaaatcatag tccaaccatt tcaaaaaggc
     6301 tagagaaatg aagaaattga aaattattat acataaccca gtaaatgagt agccatcata
     6361 tacttgccct tgtcccaaaa atggaagcac aaaataggag actcctctat aaaagagatt
     6421 caccaatatc attggaaaga gagcataaaa gaaaaggagt tttttaggaa gccctcttaa
     6481 caataagaaa gacaagccta tgccgtacaa gggttccata aaataagata ggtaaacatt
     6541 tcctactata tagctaatca ttacaaaaac aaagaccaac agtatcttca aaagaaaggc
     6601 cttaaaaatc ctctcgaaag taagattaat tccatccacc ttaaagaaaa tgacaatttc
     6661 tagcccatta gtaataagtg tatgcaataa tatccaaaca atattcataa actctcctag
     6721 ttcagtgtaa gttattaata gcctcagaca cttccctgac cttataacgg gcgattagac
     6781 aacttcctcc attgggaaag aaaagcagtt tttctttctt atccaaatgc accacatttg
     6841 caggattgat gagaaaggag cgatggcact gcaaaagacg aggttcctgc ttaaaaacct
     6901 cctctaaact cgctgtaaat tccagcctgt ctgtcttggt atagagaata acacgatggg
     6961 gtcttgggga tgtttcgaga tagtaaacct ctttaaaagg atactggaat tgggcaaatt
     7021 ttgatttaaa gtaaaagcaa tcttccgcca gacttttact atcttgacta ttggcataga
     7081 ggagggctgt ctcgattcga gattcaaact cctctgccga aagggcctta tcaatatagt
     7141 ccagagcaga cacttggtag cgaaaggaca ggggcataaa ctccgagtga gtcgtcacaa
     7201 agacaatcag ggcatagggg tctcgatccc gaatctttct agccacttcc agccccttca
     7261 tctcctcatt tcgaatctca atatccaaaa agaatagctg atgggccccc ttctcatgca
     7321 cctctgccag cagttggtct ggcttgccaa atacctcaaa agagctggga gtgatatgat
     7381 gttccttcaa gagtttctca atcgtcgttt caatcctagt ctgttgggaa aaatcatcct
     7441 ctaaaacaaa tattctcatc ttcttactct ccctctttca accatttttg acgaatttct
     7501 ctatagcgac gtctggcata cttgacagcg tattgacctt cttctccgag aaaaaggatt
     7561 ctttcttgaa aatcaatcga ttttaattta tcaagattaa ctaaacaatt tcgatgacat
     7621 ctcatcaagg tttccccaca ttggttctca agattactta aattttgaac catattaaaa
     7681 ctagcttttt ctgtaacaat ctgtacggta tgggctttag ttggatgtgt ttggatatag
     7741 tagatatcgt cgatgtttac tttatagact gttttctgtg tctgaataat catatgtttc
     7801 attggattct cctcctaaga aaagaataac agaaaaggtc tagcccaagc ccacccaatc
     7861 ctaaacagtc tttgaaaact cctaaaagga ttattttcta caacatcatg atgagcttac
     7921 aactatttta tcataaaatt cactcagcgc aattcaagac atttcaatga caattaaaga
     7981 tttgaataaa aaaaaagaat taaaagtgat aaactaacag tatcaaaaca cagttgccag
     8041 aagtaagact ggcacccaga ttaaaggagg cattcccatg acagatacag accccatcaa
     8101 aagagctcat actttgatta ctgacttaaa caaagcctac caagcatgca aacaggcaag
     8161 cgctgacgac gtccgctttc aggagcaatt aaactctatt cttggttttc tagccaaggc
     8221 tgaaacagtg gataatcgat tcttgattga attggaaaaa ttttaccaga cttccagtct
     8281 tctcatggga ctcagcgctc ttgatccaga tgctccaact cgcgccgctt ggcgggccta
     8341 tgaccgcttc cactttgacc aagtcaagac caagttaata ctcaatgaaa atcaaagagc
     8401 aaactaggaa gctagccgca agctgtactt gagtacggta agacgacgct gacgtggttt
     8461 gaagagattt tcgaagagta taagtctcta cggaccaacc attatcctgt agtaacaaaa
     8521 aagaagctga gacagactga actcaacttc ttttttagtg tcgtatcagc aatgttagtc
     8581 ctgcatctga cgttttacct gataaggcaa atacaagact tgtaaaacca aaccagctcc
     8641 cagtaaggct agaagggcta gtttttcttg aaaggtaatc aacccaacaa ctaattccac
     8701 aagtaaaaca aaactggtca atcctcgaac tacctcctgt aagccttttt ccttttgccc
     8761 cttgtccagc ggaaagagtt gggtcaaata ctggtagtca aaggcatgat agagggccag
     8821 caactggaag agcaagaggt agttaaagag aactaccact gctgtcgcaa tccaagcttg
     8881 ctcgataaaa acctgcgcca gtacggaaag taagagaaga cgaagactga gagcaaagag
     8941 gtcgccattt cgcagataag aacgcagata gagattttgc caaatcttcc caggcacctt
     9001 ctgaacagcc tttaagataa agtccagata ggcacgacgc ttaacgctgt ttgaaattcc
     9061 cttgacctgc gtaaagaggg caaagaaacg aagcaagact tgcttacgct tgctttcttg
     9121 agaaataaca tagtcccagt ccagtccagt ttcagtgaaa aatttgctgg ccttttgacg
     9181 aaagtggaaa tattttccta cccccaataa aagcacatag agcagaaaaa ctggcaagcc
     9241 ataacccatt gctaaaaata aaggcgcaaa taacagcaag aaaagggtct gtacaaagag
     9301 ccaaaagact agggaaatgc cagtttgacg cttgagatgg agcttgattt cctcttctcc
     9361 aactaagaga aagagcttgt ctggagcctc catataggtg gcaattcctc cccaaagtaa
     9421 aagtaaaaca gacgtaattc ctacaaacaa aaggataggc caatgatttt caggaaaatg
     9481 ttgtaagagt tgactgtact ggtaggctag aaagcccaac aggacaagca ggaacaagac
     9541 aaagtggtca ttgagcacat agcgcagata accaagacac tccttacgaa aggcctgctt
     9601 tctctttaaa aacaagtctt tcataggtcc tcctcttttg tcagagccaa gtaaatatca
     9661 ttcaaactag cctcaggcat atcaaaggct tcgcgtagtt gcaggagatt gcctttggca
     9721 cgcacctctc ccttgtgaag aatgacaaag gcatcacaca tcttctccgc cgaatccagc
     9781 acgtgggtac tcatgagaat agacttgccc ttttgcttct ccacttccaa aagctgaatc
     9841 aaatcagaaa tagctagcgg atcaagacca aggaaaggct catccacgat gaaaagactt
     9901 ggatccacca caaaagcaca gataatcatg accttctgct tcatcccttt tgaaaaatga
     9961 acagggaacc agtctaattt ctggtccaga cggaacatct ttaacaaggg ctctactcgt
    10021 tcgaaagcca ctttttgctc aataccgtaa gccatagcaa ccgtttcgat atgctctctg
    10081 agggtcaatt cctcatacag actaggcgtc tcaggaatgt agccaatctg cttgcggtag
    10141 ctagtcgcat ctccttgcag agtcaggcca ttgatattga tggagccact ataaggtgcc
    10201 aacagaccga taatctcatt gatcgtcgtt gatttcccag caccattgag accaatcaaa
    10261 ccgaccaact gcccactttc aacagtaaag gacacatctt tcaaaacagg aacatgaaca
    10321 tagccacctg tcaggttttt aatttctaac atattttctc caaatctggt ataatgtagc
    10381 tatattatat caaaattcag tacagtagag gtagatttta tgtcagattg cattttttgt
    10441 aaaatcatcg caggggaaat tcctgcttca aaagtatatg aagatgagca ggtccttgcc
    10501 tttcttgata tctctcaagt aacactagga cacaccttgg tcgtgccaaa agaacactat
    10561 cgcaatcttt tggagatgga tgctacgagc gccagccaac tctttgccca agtaccaaaa
    10621 gtagctcaaa aagtcatgaa agtcactaag gctgctggta tgaatatcat ttccaactgt
    10681 gaagaagtcg ctggtcaaac agtttttcat actcacgttc accttgtgcc tcgctacagt
    10741 gctgacgatg acctcaagat tgattttatc gcccacgaac cagactttga caaacttgct
    10801 caagtcgctg aaaccatcaa aaacgcttaa ggagttgcta tgaaattatc caacctactg
    10861 ctatttgcag gagctgcagc cggaagttat ctggttacaa aaaatcgcca aaccatcaca
    10921 gatgaagtct tgaataccac tgaccgcgtt caagctatca aggacgatgt ggatattatc
    10981 caaaacagcc tgcaaatcat taaccagcaa aaagaactta tcaaggaata ccaagaagac
    11041 ttgacttaca agtttaaggt cttggaaaag gatatccaga ctagactagc tgtgataaaa
    11101 gaaatgcagg gaactgaaga taagtaaaaa gagccccccg gctctttttt aaaacgtaaa
    11161 caagttatag tgaattgaat ttagaatagc acaccatagt ttctaaaaca ttgttagaga
    11221 ttactttaaa atcctcttat caatttgttc atattctatt tcaatctatt atatatatcc
    11281 catcaactat gcatcataat ttaggtaact catactcaat gaaaatcaaa aagcaaacta
    11341 ggaaactagc cacgggctgc tcaaaacact gttttgaggt tgtagatacg actcacatat
    11401 atacggcaag ccgacgctga cgtggtttga agagattttc aaagagtatt attctccatc
    11461 aaaggcatct ttaatatgat caaagaagcc ttttttcttt ggatttactt tcaagtcacc
    11521 agcagccgcg aattctttca aggctacttt ttggcggtcg ttcaagcctg tcggtgttac
    11581 gacattaaca gtaacgtatt ggtcaccaac tgcaccgcca cgaaggctcg gtgccccctt
    11641 actacgtagg cggaatttct taccagtctg agttccctct ggaataacca attcaacatc
    11701 accgtgaaca gttggaatat ctactgtatc accaagagcc gcttggacaa agttgaggtt
    11761 gagattgtag aagatagtcg ttccttcacg ttcaaacttg tcgctagctt ccacagaaac
    11821 tactacatac aagtcaccat aaggtccacc gttaaagcct gcttcacctt gaccagcgag
    11881 gcgaatttgt tgacctgttt ccacaccagc agggattttc acatgtacgc tatgagcttg
    11941 tttctcatga cctgttccat gacaggttgt acatggatat ttgatttctt ttccttggcc
    12001 gtgacagaca tcacaggtta cttggcgacg catcatacca agaggagtct gcgtatcgac
    12061 gttaatgaca ccagcgccat gacagcgtcc acaagtgact ggacttgtcc ctggcttagc
    12121 accagagcca ttacatgtac gacagccagc ttcacgatga tacttaactt ccttctcagt
    12181 tccgaagata gcttcttcaa aggtcaaatt gacacgatac tggagatcat ctccttggcg
    12241 aggagcgttt ggattgcgcg aagaaccgcc tccgccgaag aaacttgaga aaatatcctc
    12301 aaaaccaccg aagccacctg ccccattgaa accgccgaaa ccaccatctc caccaaaacc
    12361 accattggcg cctgcagcac catactggtc ataggcagca cgtttttggt cgtcactcaa
    12421 agtctcatag gcttcttgaa cttccttgta cttgtcctca gcaccaggct ccttgttgat
    12481 atctgggtga tattttttgg aaagcttacg ataagccttt ttgatttcgt ctgccgaagc
    12541 gtttttggat acccccagac gatcataaaa ttcagtattg ttcataattc aagatacaaa
    12601 gggcgtcaaa cggacacagc catctaggag ttttgacgac ggacgcttat gtcctagaaa
    12661 aaactatctt tttggcacag tccgtagccc gtgttcagtt acgaacaccc ttattccttt
    12721 ctattgatgt tctgaatcga accaccattt aggtcggatt caattccttt cttttatatt
    12781 tagtaagaaa ttctgaaacc cgtgttcagt tacgaacact ctttgttcct ttctattgat
    12841 gagacaaaac ccaaacaaat gagattccgt ccctttttat cgaaaaacag aggctgggtt
    12901 gcaacctctg caaataagta aattaacttt attttgattt taaatatcct ataagtacag
    12961 aaatatttat atatttttgt ctcttcttag tatttgccta tataattcca attgatcata
    13021 agaaatacaa ctactgtcca aatcatacca attatgaacg gtattacaaa tttatatgtt
    13081 tgtatttcta atgatatcat agctgatacc atcgccgata caaatgcaga caacaatact
    13141 gaagtaacaa aattccttac cgcttcatca tttttgacac aactatcatg ctcagctaat
    13201 ataatttctc tatatatagt caaacattct actggaatat tatctataaa accttttgct
    13261 gcttcatagt tgtcagcttg attacaaaaa tcattataaa cttttcgtgt attttttaga
    13321 tactcatcat ccaatacact catcttattt ttccgtaaac tctccgtcta cgacgtcatc
    13381 gcctgcgttt cctgttgctt gtgcgccttc tgctccttct tgagcttgtt gcgctgctgc
    13441 ggcttgttcg tagagtttca cagcaaggcc ttgagctttt tcgttcaacg cttcaagttt
    13501 cgctttcatg tcgtccaagt tgttgtcttc ttgagctttc ttaaggtcat caagggcagc
    13561 ttgggcagcg tcacgttctg cgtcgaagcc tttaccttca gtttccttga ttgtcttttc
    13621 agtcgcaaag attgcttggt ctacttcatt acgaaggtct acttcttctt tacgtttctt
    13681 atcagcttca gcgtttgctt ctgcatcttt catcatgcgg tcgatttctt cgtcagtcaa
    13741 acctgagttc gattggatga caatagtttg ttctttttga gttccaaggt ctttggcctt
    13801 aacagacacg ataccgttct tgtcgatgtc aaatgttact tcgatttgag gaattccacg
    13861 aggtgcagct gggatatcag tcaattggaa gcgtccaaga gtcttgttat ctgctgccat
    13921 tgggcgttca ccttgaagaa cgtggatatc aacggctggt tggttgtctg ctgctgttga
    13981 gaagacttgt gatttagatg ttgggattgt agtgttgcga tcgataagtt ttgtaaatac
    14041 tccacccatt gtttcgatac caagtgacaa tggcgttaca tcaagaagga caacgtcctt
    14101 gacatcacca gtaatcacac caccttggat agccgcaccc atagcaacta cttcatcagg
    14161 gtttactgat ttgtttggtt ctttaccagt ttcagcttta acagcttcaa caacggcagg
    14221 gatacgagtt gaaccaccaa caaggataac ttcgtcgatt tctgacaagc tcaaacctgc
    14281 atctgaaagg gcttgacgaa ctggaacttt tgtacgttca acaaggtcac gagtcaaatc
    14341 gtcaaatttc gcacgagtca aagtcatttc caagtgaaga ggtccagctt cacctgcagt
    14401 gataaatggc aagctgattt gtgttgaagt tacaccagaa aggtctttct tcgctttttc
    14461 agccgcatct ttcaaacgtt gcattgccat cttgtcagta gacaagtcga taccgttttc
    14521 tttcttgaat tctgctacca agtggtcaat gattttttgg tcaaagtcgt caccaccaag
    14581 tttgttgtcc cctgcagttg acaatacgtc gaagacaccg tcacccaatt caaggataga
    14641 gacgtcgaat gtaccaccac caaggtcaaa taccaagatt ttttcttctt tgtcagtctt
    14701 gtccaaacca taagcaagag ctgctgcagt tggttcgtta acaatacgtt ctacttcaag
    14761 accagcaatt ttaccagcgt cttttgttgc ttgacgttga gcgtcgttga agtaagccgg
    14821 aactgtgata acagctttgg ttactttctc accaaggtag tcttcagcgt agcctttcaa
    14881 gtattgaagg atcatagctg agatttcttg tggagtgtat tcttttccat ttgcagaaac
    14941 tttttcagaa gttcccatct tagatttgat agagataact gtatctgggt ttgtgactgc
    15001 ttgacgtttt gcagcatcac caacgatgat ttctccgttt ttgaatgaga ctacagatgg
    15061 agttgtgcgg tttccttctg ggtttgcgat gattttgctt tcagttcctt caagaactgc
    15121 aactgctgag tttgttgtac ctaagtcaat accgataatt ttagacatgt gtttttctcc
    15181 ttgttagtta attttctatt tttctttttg atactcttct taagtggcga cgccgtcaga
    15241 gcttgacttc gtcagtctct ttgactaaac tttgagccta aggtctcaaa atttgcgcaa
    15301 atagcgccac ggcgaagagt atcgtctttg gttcgcttcg ctcactatta caaagcaaaa
    15361 catattttat ctttcttcat agtttattgt cgtttcggac aagttttcta ttatgtaaat
    15421 tgcgacacga ggagtcgaaa tcgattttat ttcgacgacg agttagtaag gaagctaggc
    15481 aaacgccata gcaattgccg ttttctgacg agttgcttta gctaccgtca gaattgccga
    15541 atcgaacacg ccctaagctc tgagtaaaaa agatagattt tcttgtgttc atcgaacact
    15601 tcgtcaatct cctattttta ctgcgagctt tttacgagct ttgtatctta gttatacacc
    15661 actaccattg ctgggcgtag gatgcggtca tggagtttgt agcctttttg aaagacttgg
    15721 gcgatggtat ctactgggtg ttcatcgtct gctgggagag tttggatggc catatggtag
    15781 ttatggtcaa attcgccatc tgctgcgatt tcttcaattc cttcttcttt caaagcgtga
    15841 atcaagcttt cttgcaccat ccccaagccc ttcttcacat catctgtcaa accttcaact
    15901 gcaagtgcac gctcaaggtt gtcaagagat ggtaagattg cttttgccaa gtcctggcta
    15961 cgataacgtt gcaagttttg acgttcttca ttggcacggc gttggatatt ttgcatttct
    16021 gcatgagcgc gaagatattt gttttcgaac tcatctgcac gttcatttgc caagtccaac
    16081 ttagactttt caggagttgt ttcttcagct gtttccacaa cttcctcttc ttgaacttct
    16141 tctacttctt cattttttat atcttgggcc atgttcgcct cctttaatga tttcaatctt
    16201 aatgtacttc gtaatgatta ctgctgaggt agcggtaaaa atctgtcaac ttcatagtca
    16261 aaacacggtt gaccacattg acttgattga ttagctgttg gtaatccaga ttaactggac
    16321 cgataatggc tagaattcca actcctcgat aaggaatgag gaacttacta ctaatcaccg
    16381 ctaggtcagc taaacaggac tcttgaccgt ctgcaacacg aacattttgc atctgatcct
    16441 cacgcaaccc ctcacgaatc tccaaggcca ccttttgcgg ttggtcaaag aactgatagg
    16501 cttctagatt ggcaaaattc aagagattga ccttgcccgc catcacaatg ttttcgttga
    16561 acatttcctt aaagatgtgt tcaaagagat cgatgacatt atccgttgtt gtaaagtaac
    16621 gctggataat ctgcggaatc tccgtccgaa tcttgtagtg aatatctaaa acggtgtgac
    16681 cgaggaaacg ttcctgaatg atgctcttca gtttcagcaa atcctcctgc aagaagttcc
    16741 ttggaatcag aaactgacta gtaaccgttc gcgactcgtc tagggtaaat accgccaagg
    16801 ctgtatgttg ccccaaaaca acgatatcaa aggctgtcaa acgttgcctg ctcggctcaa
    16861 catccagtgc cactaccgta cagccactca ggtctgttag caagttagca gcctcttgca
    16921 gaatatcctc caatttgaag aattcctgat caaaggcttt gacaatctca tatacctcat
    16981 tttcagccag ccggtgaaaa tccagtgagt gtttcacata gtactgaaaa ccagcaacac
    17041 ttggcatccg accgcttgaa gtatgagcct tctcaagcaa cccttgtttt tctagttccg
    17101 ccatgtcatt acgaatggtt gcactgctag agttaataga ctcttgcaag gcttttgatc
    17161 cgacaggttc gtgcgttttg gtaaagatgt caataatcag atttaaaata tcctgctgac
    17221 gctctgtaac catctcatca ctcctctctg tctgatcaat tagcactcaa tgcatccaag
    17281 tgctaactta tgattctatt atacaccctt aaaagagaat gtcaagacaa aaactcaaaa
    17341 aattagcact cttttatcaa gagtgctaaa aatcaatctg aagacctaga accttgctat
    17401 tcatctactc ggtatttcct ttttagtctg aaataaccat gaattagata agaaatcaga
    17461 aaagcatata aaacaaaaat aagaaagaaa gacatagaaa gatcctctct aaacaaactc
    17521 gtacaaacaa caagaccacc taagaaagta gttgtacagg aacgaagtct agatcgcata
    17581 acttcccatt tgagcccctt actcatatag acttgatcct ctggaagtaa atcagaagac
    17641 gatttacgaa gaatcgaaca agaacctgct cctatcaatt cccaacctct atctctaaaa
    17701 tcttgcagtt catgcttata ttttttaaga aatctagaat catagatacg gtagatgaca
    17761 tcgtctggtt gacattggtc aaaatagaac aaaccaaaac gactcgttct atacctccaa
    17821 cctttcaaat gcatctcatg taaatattct tcttacttgt ccaaatcaac aatggtgaaa
    17881 atccgaaatt ctactctgct attcattgtc ttaccccaaa attagaaaac atgcctggcg
    17941 ttatttatta gataattctt tccacttttg actcaatctc caaaaaatat aagaaatctg
    18001 aatcgcaaaa actatcaata aaacccaatc tattatgaaa atcaaaaaca ctttccaact
    18061 gaaagaacta cctccagtga caaactttga gaaaaacggt agtagagcta aaaagagaag
    18121 taaaatagga agcatccgca ttgttaaaat ccgtttggca taaaaaaatc tttatttaaa
    18181 ctaaaatatt atagcaaaat ttacgccagt ttttgaacgg ctgatgtaga tattttatac
    18241 tttcaaaatg tttaaatgtg attatttatt tttgaaaaat agctcaccag cccgactgaa
    18301 agtgcttata gaatgataat aagtcgcctg ccgaaaacag cgaaaaatag cggtgttatg
    18361 cggagataat ctgacgcgat gcgaaagtat attgcatact tattttcaac aatttagcag
    18421 agtattttta taagtgtgat ataatagaag tataatttgt tctgatagtt tattttatgg
    18481 agaagtagat ttttagaatg cggagggttc aatatggttg agtttataaa gtctaagaaa
    18541 gaaatgagtg aggaggatat taaagcaaat ttcatcactc ctgctattgt atccaaagga
    18601 tggaaaaatg gtgagcatat cgcttacgaa gaatacttca ctgatggtcg aattgaagtt
    18661 agaggagata aggctcgtcg taaagaagga aaaaaatcag actattcact gtattaccaa
    18721 tttggaactc gaattgcaat tgttgaggca aaggataata aacacagcgt tcgagcagga
    18781 ttacaacaag ctattgaata tggagagatt ttagatgttc catttgttta ttcttcgaat
    18841 ggtgatggct ttattgaaca cgaccgtatc acgagagaag aacgtgagct ggagttagac
    18901 gaattcccta ctcgtgaaga attattttct cgtatgacga aggaaaaagg attgacgtac
    18961 gaaattacag aagctatctc aactccatac tatacagacg ccttctcaat gaaaacgcca
    19021 cgctattatc agcaaatagc tatcaaccgt actattgaaa cagttgccag aggacaaaaa
    19081 cgagtaatgt ttgtgatggc aacaggaacg gggaaaacgt tcatggcttt tcaaattatt
    19141 catcgccttc gaaaagctgg tttggctaaa cgagttttat tcttagcaga tagaaacatc
    19201 ttagtagacc aaacgatggc tgaagacttt aggccattcg aaaaggtaat gacgaaaatt
    19261 acaccaaaac ttttgactgc tcctgaaaaa ttaaattctt ttgaaattta tctagggctt
    19321 tatcagcaac taactggtga agatggaact gaaacacatt atcaaaaatt tgacaaagac
    19381 ttctttgatt taatcgtaat tgatgaagcg caccgtggtt cagctaagga aaacagtaac
    19441 tggcgtaagg taattgatta tttcagttct gcgacacaga ttgggatgac cgctactcct
    19501 aaagaaacca agaatgcttc caatatggaa tactttggtg agccaatcta tacttatagt
    19561 ttaaaacagg gaatcgagga tggttttttg gctccatatc gtgttatgag ggttaattta
    19621 gatgtggatg tgggtggtta tcgtccagaa actggaaaag ttgatgctaa cggacaatta
    19681 atagaagata ggtactacgg caggaaagat tttgataaaa ccattgtcat tgatgataga
    19741 acgcaaagag ttgccaagtt tgtttctgat tatatgaagc aaaacaatgc acgatttgat
    19801 aaaacaattg ttttttgtgt tgatattgac catgccgagc gaatgcgtgc tgcacttgta
    19861 aaagagaatc tagacttagt ccaagaagac tatcgttatg tcatgcaagt aactggtgac
    19921 aacgctgaag gaaaagctca actggataac tttatggatg tcaattctaa ttttcccgct
    19981 attgtaacaa cgtctaaatt attaacgaca ggagttaatg ctaaaacatg tcgtttgatt
    20041 gttttagact ctaatatcca atccatgact gaatttaaac aaattattgg tcgtggcaca
    20101 cgtctttatc ctcaaaaggg gaaagaattt tttacgatta ttgattttcg aaatgttacc
    20161 aatttgtttg ctgaccctga ttttgatggt gatccagtga aggtgctgga aacaggtgcg
    20221 aaaacagtca gtggttctac gcccggtttc gtagatgagg aaggtgaccc agtagaaaaa
    20281 tatatcgtta cagacaagca ggttaccatt cttaattcta ctgttcaagt attggatgaa
    20341 aacgggaaac tgattaccga aagcctgacc gactacactc gaaagaatat cttaggtagc
    20401 tacgccactt tgaacgattt tatcacagtt tggcatacgg cagataagaa gaagcttatc
    20461 ttagacgaac tttataaaaa aggagtttat ctagatgcta ttcgagagtc ggagggaata
    20521 tcagaacaag aaatcgatga ttttgattta ctcctaaaac ttgcctatgg tcaaaaagaa
    20581 ttaaccaaaa cggaacgtat caataaactc aaacaaagcg gatatttata taaatatagt
    20641 gaggaagcgc gtgctgtttt ggaaatttta ctgaacaaat acatggataa aggtattgga
    20701 gaactcgaaa gcattgaaac attaaaactt ccagaatttc agatatatgg tggaaccttc
    20761 aaaatcatca atacttattt tggagataaa aaacgatatt tacaagcaat taaagaattg
    20821 gagcaagagc tatttacaag caattaaaga attggagcaa gagctattta cagtagctta
    20881 atgaaaggaa agtatgtcaa ttacatcatt tgtaaaaaga attcaagata tcactcgaaa
    20941 cgatgctggt gttaatggtg atgctcaacg tattgagcaa atgtcttggt tattattctt
    21001 aaaaatttat gatagccgtg aaatggtttg ggaattagaa gaagacgagt atgagtcaat
    21061 tatcccagag gaattaaaat ggcgaaattg ggctcatgct caaaatgggg aacgggtatt
    21121 gacaggcgat gaattacttg attttgtcaa taacaagtta ttcaaagagt tgaaagagct
    21181 tgaaataact tcaattatgc ctattcgaaa aacgattgtt aaatcagctt ttgaagatgc
    21241 gaacaactat atgaaaaatg gcgtcttgtt acgccaagtc atcaatgtta ttgatgaagt
    21301 tgatttcaat agccctgaag atcgtcattc gtttaatgat atttacgaaa aaattcttaa
    21361 agatattcaa aatgctggga actcaggaga attttatacg ccacgtgcag cgactgattt
    21421 tattgccgaa gttcttaacc caaaacttgg agaatcaatg gcagaccttg cttgcggaac
    21481 aggaggcttc ttgacttcga ctctgaaccg tttaagtagt caacgtaaaa ctagtgaaga
    21541 taccaaaaaa tataatacag ctgtttttgg tattgaaaag aaagcatttc ctcatctttt
    21601 agcagttaca aatctgtttc ttcacgaaat tgatgaccct aaaattgttc atggaaatac
    21661 tttggagaaa aatgttcgtg aatatacgga tgatgaaaaa tttgacatta ttatgatgaa
    21721 tccacctttt ggagggtcag aattagaaac aataaaaaat aactttccag cagaattacg
    21781 gagttctgaa acagctgatt tatttatggc tgtcattatg tatcgtttga aagaaaatgg
    21841 tcgtgttgga gttattttac ctgatggttt tctatttggt gaaggtgtaa aaactcgctt
    21901 gaaacaaaaa ctggtagatg agttcaactt gcatacgatt attaggttgc ctcatagtgt
    21961 ctttgcaccg tatacaggaa tccatacgaa cattcttttc tttgataaaa caaagaaaac
    22021 agaagaaact tggttttatc gtttagatat gccagatggt tataaaaatt tctcgaaaac
    22081 taagccgatg aagtcagaac acttcaatcc tgttcgtgac tggtgggaaa atcgtgaaga
    22141 gattctggaa ggtaagttct acaaatctaa atcatttaca cctagtgaat tggctgagtt
    22201 gaattataat ttagaccagt gtggttttcc aaaagaggaa gaggaaatct taaatccctt
    22261 tgagttgatt cagaattatc aagcggaaag agcaacttta aatcataaga ttgataatgt
    22321 attagctgat attttgcagt tgttggagga caaataatga caccagaaca acttaaagca
    22381 agtattctcc aaagagcgat ggaagggaaa ttagtgccgc aaaatcccaa tgacgaacct
    22441 gcaagtgaat tattaaagag aattaaagct gaaaaagaaa aacttatcag tgaaggaaaa
    22501 atcaaacgag ataaaaaaga aactgagata tttcgtggtg atgatgggaa acattatggg
    22561 aagtttgctg atggaagtac tcaagaaatt gatgttcctt atgatattcc tgatacttgg
    22621 gagtgggtga ggttttctac attggttgaa attgtcagag gtggctctcc acgaccaatc
    22681 aaagattatc ttacttctga agtagatgga ataaattgga taaaaatagg tgatactgaa
    22741 aagggtgaaa agtatataaa taatgttaaa gaaaaaatca aaaaatcagg gcttaacaaa
    22801 actagatttg taaaaaaagg tacatttttg ttaactaatt ctatgagttt tggtagacct
    22861 tatattttga atgttgatgg tgcaatacac gatggatggt tggctatttc gaactatgaa
    22921 aactcattaa ataaagatta cctattctat attctttcat caaatgtagt ttattctcaa
    22981 tttctatctc taattagtgg agctgttgtg aaaaacttga atagtgataa agttgcttct
    23041 attcttatc
//
LOCUS       DAVAGB010000032        22995 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVAGB010000032 DAVAGB010000000
VERSION     DAVAGB010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22995
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.032"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            56..238
                     /locus_tag="VQO19_001422"
     CDS             56..238
                     /locus_tag="VQO19_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET1349671.1"
                     /translation="MKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTIL
                     RLESASIASELVAGLR"
     gene            538..1377
                     /locus_tag="VQO19_001423"
     CDS             538..1377
                     /locus_tag="VQO19_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET1349672.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            1395..3233
                     /locus_tag="VQO19_001424"
     CDS             1395..3233
                     /locus_tag="VQO19_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET1349673.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVEAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            3246..4661
                     /locus_tag="VQO19_001425"
     CDS             3246..4661
                     /locus_tag="VQO19_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET1349674.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLLGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     EEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            5253..6299
                     /gene="pheS"
                     /locus_tag="VQO19_001426"
     CDS             5253..6299
                     /gene="pheS"
                     /locus_tag="VQO19_001426"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HET1349675.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            6299..6808
                     /locus_tag="VQO19_001427"
     CDS             6299..6808
                     /locus_tag="VQO19_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET1349676.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GIGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            6885..9290
                     /locus_tag="VQO19_001428"
     CDS             6885..9290
                     /locus_tag="VQO19_001428"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HET1349677.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVESVESPAADLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEARQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPENTVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIGTDK
                     APYYAARILDNVIIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SRVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASMIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTDQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPREELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQVSLEEKVNA
                     EVR"
     gene            complement(9358..10359)
                     /locus_tag="VQO19_001429"
     CDS             complement(9358..10359)
                     /locus_tag="VQO19_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET1349678.1"
                     /translation="MIKTFLSALSVILFVIPIIAYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMASILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVRDLDIVSFQNSDHRCIFTEITF"
     gene            10506..10909
                     /locus_tag="VQO19_001430"
                     /pseudo
     CDS             10506..10909
                     /locus_tag="VQO19_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            11035..11301
                     /locus_tag="VQO19_001431"
     CDS             11035..11301
                     /locus_tag="VQO19_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET1349679.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            11562..13811
                     /gene="metE"
                     /locus_tag="VQO19_001432"
     CDS             11562..13811
                     /gene="metE"
                     /locus_tag="VQO19_001432"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HET1349680.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVVAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYAGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVASDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            13875..14741
                     /gene="metF"
                     /locus_tag="VQO19_001433"
     CDS             13875..14741
                     /gene="metF"
                     /locus_tag="VQO19_001433"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HET1349681.1"
                     /translation="MSCQTPSLSFEVFPPNPAVGNDNIILALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIELIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNEHFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            15426..17639
                     /gene="pnp"
                     /locus_tag="VQO19_001434"
     CDS             15426..17639
                     /gene="pnp"
                     /locus_tag="VQO19_001434"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET1349682.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            17655..18272
                     /gene="cysE"
                     /locus_tag="VQO19_001435"
     CDS             17655..18272
                     /gene="cysE"
                     /locus_tag="VQO19_001435"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HET1349683.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHSFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHAVEEKREYYVNKLEQAKDASHRSSGL"
     gene            18284..19168
                     /locus_tag="VQO19_001436"
     CDS             18284..19168
                     /locus_tag="VQO19_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET1349684.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEILLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSSDT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            19255..20598
                     /locus_tag="VQO19_001437"
     CDS             19255..20598
                     /locus_tag="VQO19_001437"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HET1349685.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            20591..20977
                     /locus_tag="VQO19_001438"
     CDS             20591..20977
                     /locus_tag="VQO19_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HET1349686.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            20981..21865
                     /locus_tag="VQO19_001439"
     CDS             20981..21865
                     /locus_tag="VQO19_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HET1349687.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLTSW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            22002..22601
                     /locus_tag="VQO19_001440"
     CDS             22002..22601
                     /locus_tag="VQO19_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349688.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGYNFSSVSSS
                     SQTAKYEGTGYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEVTVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNHP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            22744..22914
                     /locus_tag="VQO19_001441"
                     /pseudo
     CDS             22744..22914
                     /locus_tag="VQO19_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         7122 a         4117 c         5047 g         6709 t
ORIGIN      
        1 aaaacacccc aaaagttaga ttttttctgt ctaacttttg gggtgtagtt cacagttgaa
       61 gagccagaaa attaaagtgt cttttactca atcaaaaata gtaacgccta ttcttttggt
      121 gaataagact attgtttggt atggtgcaat gccattatta gggaaggtag atgagatgac
      181 catattacgt ttggaatcag ctagtatagc ttctgaacta gtggcaggtt tacgatagag
      241 aaaattttta aaaatttcta tgtatgattt tcatttcttt agtgagactg ttgtcattat
      301 cacattcgaa tcacacaaaa taaaaaaatt tctataagta cttgacaaat agattgaaat
      361 atcttaaaat gaaaatggtt acagagttat taatgattta agcttcatgt caccattaaa
      421 aattgaaata aaaggatgtt atcactaata caagtgagca ggaacctatt taatcacatc
      481 ggaagaagtt tcttgatgtt tttaagtagg ttccttttat tttaaaaggg aaattttatg
      541 atcataaaac gaatactaaa ccacaatgcc gtaattgcgc aaagtaaaaa agatatcgat
      601 attcttcttt ttggaagggg aatagctttt ggaagaaaaa ctggagataa agtaaatcca
      661 attgatattg agaaaagttt ttttctcaaa aatagagata atatgacccg ttttacagag
      721 atgtttatta acgttccttt ggagttggtg tacatcaccg aaaaaataat taacctaggt
      781 aaaataacat tgggtaataa ttttgatgaa attatctata ttaatttaac ggatcatatt
      841 tcttcgagca tagaacgtta taaagaagga gttattattt cgaatcccct acgctgggaa
      901 atctcgaaat attataaaga agaatttgaa cttgggaaaa gggctttaca aataataaaa
      961 aaagagttag gtattgaact tccaattgac gaagctgcat tcatagcgct acattttgtt
     1021 aatgctaatt tagaaaataa ttttcaagag tcgtataaaa tcactgaaat aattatggga
     1081 attgagaaaa tcattcaaga tttctattgt actgagttta accaagattc tattgattat
     1141 tatagattca taactcatat aaaattattt gcccatcgct tggttgaaaa tacaacttat
     1201 tgtgacgatg atgatgaaga cttgttagca ttaatgaaaa ataaatatcc tagagaatat
     1261 gaatgtggtg aacaggtggc aatgtttata caaacggagt acaattattt gctgacttct
     1321 agtgaattag tttatttgat ggctcatatt cgtcgcttaa caaaaaattt agattaatag
     1381 aataggagaa taccatgagt tataaagata cggtacaaaa aatcctcgat gtaattggag
     1441 gtgaaaaaaa tgtcaataga gttacccatt gtgtaacacg tttaagatta gaattaaaag
     1501 atgaaaattt agtcaatgat gatgatgtga agaagatacc aggtgtaata ggtattatga
     1561 aaaagaatgg acaatatcaa attatacttg gtaatgatgt agctaattat tataaagaat
     1621 tcgttaaact tggcaatttt gaatccgatt cagttgttca agggcacaaa gggaatattt
     1681 tagaaagaat cattgagtat atcgctggtt ccatgactcc aatcattcca gcaatgttag
     1741 ggggaggtat gttgaaagtc ttggtaatca ttttaccaat gcttggtata ttgcaatcag
     1801 attctcagac tattgctttt ttgacatttt ttggggatgc tccatattat ttcttaccgc
     1861 tgttattagc ttattctgca tcacaaaaat taaaagtaac atctacatta gctatgtctg
     1921 tagcaggtgt acttctccat ccaaattttg ttcaaatggt gcaatcaggg aatcctctta
     1981 gtttatttgg tgcacctgtg acaccagcta gttatggttc atcagtcgtt ccaattctta
     2041 ttatggtttg gttgatgaaa tatattgaaa aaataattgc taaattaaca ccagctatta
     2101 ctaagagttt tttgcaacct acgctagtat tattagtatc aagctgtatt gccttagttg
     2161 tagtcggacc tattggagta attgttggtg aaggattatc aaatctagtt gggcaaatgt
     2221 atggtgtagc tggatggctt acattagcta ttcttggtgc tattatgcca tttattgtta
     2281 tgactggaat gcattgggct tttgcaccta tttttttggc ggcatctatt gctactccag
     2341 acgtattaat tcttccagca atgttagggt caaacttagc tcaaggggct gcttcgatgg
     2401 ctgttgcatt aaagagtaaa aataataata caaaacaaat tgcttttgca gcaggtttct
     2461 cagccttact tgcagggatt accgaacctg cattatatgg tgtgacttta aaatataaaa
     2521 aaccgcttta tgcagctatg attggtggtg gattagcggg attatttgca ggtcttacta
     2581 gtgttaaagc atatctattt gctgtcccat ctttgatagc gttgcctcaa tttatttatt
     2641 ctgatgtgcc atcaaatatt gtaaatgctt taattgtggc ggtcatttcg gttgttatta
     2701 cctttgtatt agcttatata tttggaatcg atgaagaaga gagttctagc aatttagaag
     2761 ttgaagctgg agtttcaaat aaaaaaatga tattttctcc tatatcagga gaaatcattc
     2821 cgttaagcga tgtccaggat aaaacatttt cagataaact aattggagac ggagtagcga
     2881 ttatcccaag tgaaggtaag gtttatgcac catttgatgg gaaaattaca aatatttttc
     2941 cgactaagca cgcaattgga ttgaagagtg atgagggtgt tgagttacta attcatattg
     3001 gattagatac tgttgagcta aaaggtcaag gttttattag tcatgtagaa gaaggagaca
     3061 gagttttcaa aaatcagttg atttttgaaa tggacttgaa tttaatcaag actaaaggct
     3121 acgaaacagt tacaccagta attgtaacga ataccaatga ttttctagat gtattagtat
     3181 tacctaataa tcagacaatc gagcattcta aggaattact ggtaatatta taatggagga
     3241 aagttatgac catttttcca gatgattttc tttggggtgg agcggttgca gctaatcaag
     3301 tagagggagc atataatgaa gatggtaagg gattatcagt tcaggatgtg ttacccaaag
     3361 gtggattagg agaagcaaca gaaaatccta cagaagataa cttaaaattg ttaggtattg
     3421 atttttatca taaatataag gaagatatat ccttgttttc tgaaatgggc tttaatgttt
     3481 ttcgtacttc tattgcatgg agtagaattt ttccaaaagg agatgaagaa gaacctaacg
     3541 aagctgggtt gaaatattat gatgaattat ttgatgaact acatgctcac gggatagaac
     3601 cacttgtaac tctttcacac tatgagactc cattatattt agcaagaaaa tatcatggat
     3661 ggattgatag gagaatgatt catttttatg aaaaatttgc tcgaacagtt ttagaaaggt
     3721 ataaagataa agttaaatat tggcttacat ttaacgaagt aaactctgtt ttggaattac
     3781 cgtttactag tggaggaata gatataccta aggagaatct ttcgaaacaa gaattatatc
     3841 aagctataca tcatgaatta gtcgcctcga gtttggttac aaaaattgct cgtgagatta
     3901 attcagagtt taaggtgggg tgtatggtat tagctatgcc agcttatcca atgactccaa
     3961 atccaaaaga tgtatgggcg actcatgagt atgagaatct aaattatcta ttttcagatg
     4021 tgcatgttag aggttattat ccgaattatg caaaaagata ttttaaggaa catgacatta
     4081 acatagagtt tgcagctgaa gatgcagagt tattaaaaaa ttatactgta gattttttat
     4141 cctttagcta ttacatgagt gtgactcaat ctgctcttcc aacacagtat aattcaggag
     4201 aagggaatat tattggtggc ttagtaaatc cttatttaga gtcttctgag tggggatggc
     4261 aaattgatcc aattggacta cgtataattt taaatagata ttatgaccgt tatcaaattc
     4321 cattatttat agtggaaaac ggattaggtg ctaaagatca actaataaaa gatgaattta
     4381 ataacttaac agtccaagat gattatagaa ttcagtatat ggaagaacat ttattgcaag
     4441 tagctgaagc tctacaagat ggtgtggaaa ttatgggcta tacatcttgg ggatgtattg
     4501 actgcgtttc tatgtccact gcacaacttt ctaaaaggta cggtctcatt tatgttgatc
     4561 gaaatgatga tggaaatggc acattcaatc gatataagaa aatgtccttt acttggtata
     4621 aaggagtgat tgaatcaaat ggagaatcct tattcaaata gtttgtttat tgatgattag
     4681 atattatcac ggttaaggca acatctcatt aaatatgaaa taaagaggtt tggaagacat
     4741 caaattctaa acctctttat tttatagggg gattaattaa tttaattttg ttacagagag
     4801 ccgattataa atagtaaact taggatagat tggttatata tagcagactg aatctaaaat
     4861 agtacgaaac aattgctaaa acatttatag aaattaattt tactttccca atcgatttgt
     4921 tttcatctta tttcaatccg ctataaagtt agataagaat aagctaacaa gcagaagtaa
     4981 gataggtctt gcaagaatgg taaaaatctg ataaactaag tagtaattga ataggaatct
     5041 gaaagactag tagcccaagg gaagtatatc agggaggaga gccgtgactg caagctctct
     5101 atatgaaagc tgggtgaatt cacttgcgca tggatttaga aatgaaggtc tgacttgtca
     5161 gatgaaaacg gatggtaccg cgtgtcaacg ctccgagtgg agtttttggc atgtggtttt
     5221 ctttttatct acgagagact gatggaggaa atatgtcaac tattgaagaa caattaaaag
     5281 cgcttcgcga agaaacgctg gctagcttga agcagattac tgctggaaat gaaaaagaga
     5341 tgcaagattt gcgtgtctct gtccttggta aaaagggttc gctcactgaa atcctcaaag
     5401 ggatgaaaga tgtttctgct gagatgcgtc caatcatcgg gaaacacgtc aatgaagctc
     5461 gtgatgtctt gactgctgct tttgaagaaa cagctaagct cttggaagaa aagaaagtcg
     5521 cggctcaact ggctagcgag agtatcgatg tgacgcttcc aggtcgtcca gttgcgactg
     5581 gtcaccgtca cgttttgaca caaaccagtg aagaaatcga agatatcttc atcggtatgg
     5641 gttatcaagt cgtggatggt tttgaagtag agcaagacta ctataacttt gaacgtatga
     5701 accttccaaa agaccaccca gctcgtgata tgcaggatac tttctatatc actgaagaaa
     5761 tcttgctccg tacccacacg tctccagttc aggcgcgtgc tatggatgcc catgattttt
     5821 ctaaaggtcc tttgaagatg atctcgccag ggcgtgtctt ccgtcgcgat acggacgatg
     5881 cgacccacag tcaccaattc caccaaatcg aaggcttggt agttgggaaa aatatctcta
     5941 tggctgatct tcaaggaacg cttcagttga ttgtccaaaa aatgtttggt gaagagcgtc
     6001 aaattcgttt gcgtccatct tacttcccat tcacagagcc atctgttgag gtggatgttt
     6061 cttgcttcaa gtgtggtgga gaaggctgta acgtatgtaa gaaaacaggt tggatcgaaa
     6121 ttatgggagc cggtatggtt cacccacgtg tccttgaaat gagtggtatc gatgcgactg
     6181 tatactctgg ttttgccttt ggtcttggac aagagcgtgt agctatgctc cgttatggaa
     6241 tcaacgatat ccgtggattc taccaaggag atgtccgctt ctcagaacag tttaaataat
     6301 gattagaaaa gtagaaatgg cagatgttga ggtgttggct aaaattgcca aacaagcctt
     6361 tcgtgaaacc tttgcgtatg ataatacgga agagcagtta caggaatact ttgaagaggc
     6421 ttatagtctg aaaactttgt caactgagtt gggaaatcct gactctgaaa cctatttcat
     6481 tatgcatgag gaggagatag ctggttttct caaagtcaac tggggaagtg ctcaaactga
     6541 gagagaatta gaggacgctt ttgaaattca acgcctctat gtgctacaaa aattccaagg
     6601 atttggaata ggtaagcaac tgtttgaatt cgcacttgaa cttgctacaa aaaatagttt
     6661 ttcttgggct tggctaggtg tttgggagca taatacaaaa gctcaagcgt tttataatcg
     6721 atatggtttt gaaaaattta gccaacatca ttttatggtt ggtcaaaaag tagatacgga
     6781 ttggttactg agaaagaaat taaggtaaga agaggattct tctattgaaa tgataggaaa
     6841 ggaaaagaac cagtgtggca atggtcattc tggagaacta aattatgctt gtatcttata
     6901 aatggttaaa agaattggtg gacattgatg tgccatcaca ggagttggct gaaaaaatgt
     6961 caaccacagg gatcgaggta gagagtgtcg aatcaccagc tgctgatctc tcaaaaattg
     7021 ttgtcggtga ggtcttgtct tgcgaagatg tgccagagac tcacctccat gtttgtcagg
     7081 ttaacgttgg cgaagaagaa gcccgtcaga tcgtttgtgg tgccccaaat gtgcgtgctg
     7141 ggatcaaggt catggtggct cttccaggag ctcgtatcgc tgataactac aaaatcaaaa
     7201 aaggaaaaat ccgtggtttg gagtcacttg gaatgatctg ttcacttggt gaattgggaa
     7261 tttctgactc agttgtgcct aaggaattcg cagatggcat ccaaatcttg ccagaaaata
     7321 ccgtgccagg tgaggaagtc ttttcttacc tagacttgga tgatgaaatc atcgaacttt
     7381 ccatcacacc aaaccgtgca gatgcccttt ctatgtgtgg agtggctcac gaagtggcag
     7441 ccatctatga caaggcagtc aactttaaag aatttactct aacagaaact aatgaagctg
     7501 cggcagatgc cctttctgtc agcattggga cagacaaggc gccttactat gcagctcgta
     7561 tcttggacaa tgtgattatc gcaccaagtc cacaatggtt gcaaaacctt ctcatgaacg
     7621 aaggcatccg tcccatcaat aacgttgtag acgtgacaaa ctacatcctg ctctactttg
     7681 gtcaacctat gcatgctttt gacttggaca catttgaagg gactgacatc cgtgtgcgtg
     7741 aagcgcgtgc tggtgaaaaa ttggtgacct tggacggtga agaacgtgac ttggacgtga
     7801 atgacctagt catcactgtt gcagacaagc cagtagccct tgcaggtgtc atgggtggtc
     7861 aagcaacaga aatctctgaa aaatctagtc gtgttgtcct tgaagctgct gttttcaatg
     7921 gtaaatctat ccgtaagaca agtggtcgcc tgaaccttcg ttcagaatcg tcttctcgct
     7981 ttgaaaaagg catcaatgtg gcaacagtca atgaagccct tgatgcggca gctagcatga
     8041 ttgcagaact tgcaggtgcg acggtgcgta agggtatcgt ttcagcgggt gagcttgata
     8101 cctctgatgt ggaagtttct tcaacccttg ctgatgttaa ccgtgtcctc ggaactgagc
     8161 tgtcttatgc tgatgtcgaa gacgtcttcc gtcgtcttgg ttttggtctt tctggaaatg
     8221 cagacagctt tacagtcagc gtaccacgtc gtcgttggga tatcacaatc gaagctgacc
     8281 tctttgaaga aatcgctcgt atctatggat atgaccgctt gccaactagt ctaccaaaag
     8341 acgatggtac agctggtgaa ttgactgtga cacaaaaact ccgccgtcaa gttcgtacca
     8401 ttgctgaagg agcaggtttg acagaaatca tcacctatgc tctaacaact cctgaaaaag
     8461 cagttgagtt tacggatcaa ccaagtaacc ttacggaact catgtggcca atgactgtgg
     8521 atcgttcagt cctccgtcaa aatatgattt caggtatcct tgataccgtt gcctacaacg
     8581 tggctcgtaa gaataaaaac ttggcccttt acgagattgg aaaagtcttt gaacaaacag
     8641 gtaatccaag agaagaactt ccaaatgaaa ttaacagttt tgcctttgcc ttgacaggct
     8701 tggttgctga aaaagatttc caaacagcag cagttccagt tgatttcttc tatgctaagg
     8761 gaatccttga agccctattt actcgcttgg gactccaagt aacctataca gcaacatctg
     8821 aaatcgctag ccttcatcca ggtcgtacag cagtcatttc actcggtgac caagttcttg
     8881 gtttccttgg ccaagtgcat ccagtcactg ctaaggctta tgatattcca gaaacgtatg
     8941 tagctgagct taacctttca gctatcgaag ctgcgcttca gccagcgact ccatttgtag
     9001 aaatcaccaa attcccggca gtcagccgtg acgttgccct tctcctcaag gcagaagtga
     9061 ctcatcaaga agttgtagat gctatccaag ctgccggcgt gaaacgtttg acagatatca
     9121 aactctttga cgtcttctca ggtgagaaat tgggacttgg tatgaagtca atggcttata
     9181 gcttgacctt ccaaaatcca gaagatagct taacggacga agaagtcgca cgctatatgg
     9241 aaaaaatcca agtatcgctc gaagaaaaag tgaatgcaga agtgcgttaa acgatagtat
     9301 gatacaaatt ccccctctag tttatgaaca ctagaggggt gattttatat aaaataatta
     9361 aaatgtgatt tctgtaaaaa tacatctatg atcagagttt tgaaaactta caatgtctaa
     9421 atctctaaca tagtagtggt ttttaggcaa taagatatga tctatcgttg cattaaaaag
     9481 ttttggactt tggctattcc aagttcctct ttcaaaaggt ggaagtgcat tcaatgcgtc
     9541 cctatgagag cttatttttg caagtgctcc atgacgcata gttgcattaa aatcacctgc
     9601 aataatagcc tttggatatt ttgaagccaa ttgattatga atgatgttta agtcttgctt
     9661 ccagatttcc attaaacctg gcagaggagg agcagtatgc aaggcaatga tatctggtat
     9721 attttgtttt ctcgaatgta atacaattgt cccgaaccgt gttgtatgaa aagttttagc
     9781 ttctgtatag aaaccataac ttttcttgac aatcacagtc acaggagcta ttccactatt
     9841 ggtaggtgga gaagtgaaaa tatcatagtt ggccatagaa agtccaactt gatgaaacaa
     9901 tagtttgatt ctctggtttt cttgctcacc tctgatattg gtagctagtt cagggaatat
     9961 agccatatcg gcatcaaaat ggctaaaaat tcgctcaata tgttgtgctt ctatttgatt
    10021 agcgacgttc caagttacta attttaaggt tttagtctta tttgatgcag aagaaagggt
    10081 tttatctgtt ccgaataata gtaatatgag cgatagtaag agcaaaatgc cagagtaaaa
    10141 ccgtatttgt ttatttttct tgtaaaaaga tagggaaaaa aatacgaaac ttaaaataga
    10201 agccatagtt gcagtagcta aggggaaggc ataaatctgt gccaagatag gtctggtaga
    10261 tagccaaata ttaagattag aagatggaaa aaaagaataa gctatgatag ggataacaaa
    10321 gagaatgacc gaaagggcag agagaaatgt tttaatcatt gtgtgagtac ctcaatttgc
    10381 aatggttgct cggagctaat gtgactttac ttgattgata ttctttttct tgtcttcctc
    10441 atagattaag tacaacccaa gtaaaaaagt tcaatttaag attgaaatga ttaaaaggca
    10501 cagaaatgca agacaattat actacaaaag gcaaacattt gacaatcgat agccgtcgct
    10561 taatcgaacg atggaaaaaa gaaggaaaat caaatagaga aattgcctct ctacttggaa
    10621 aagctcctca aactatccac actgaaatca agcgtgggac agtccgacaa tgtcttggaa
    10681 aagggcgctt caaagagatt tattctgccg actacgctca acagtcttaa gaaactaaag
    10741 gaaaagattc tccactatac ataaccaaaa attttcgcct gaaatgatgg tgatggctaa
    10801 aggggttaac gtgggaattt caaccattta ctattggatt catcgtggaa aattggggtt
    10861 aagcaagcag gatctgcttt atcctagaaa aggaaaatcg cttaagaaat aggctagcac
    10921 caactttaaa cccgctggtc aatctatcga atcataattc gctcattttt ttaaaaatac
    10981 atagacgtaa aaaaaagagg gttaagtgat gaagaatagt gctattggga gtaattggaa
    11041 ggatgtccat ctgagctctt tagcaaggag gaaatccttg aaagtgatat gcgagtggct
    11101 atcatgagcg agttgattga ggctaggtat gaacaaggaa tcagtcagaa aaagctggaa
    11161 gaagtcagtg gaataagcca gcctgtcata gctaggatgg agacaggaga gagcagtctt
    11221 cagttggata cggtcttaaa agttctaacc agtctaggaa agacactagc agtcgttcca
    11281 cttgaacagg ggaaaagttg actagaatca gttatagtct tttctaataa caggtcatag
    11341 tcacttataa gaattactaa taacatgttt tagtattcta attggaatat agctgtaaag
    11401 taagaattac aaaggatttg agatgtttgc ttcaagtctt tttcttttgt ccgaaacaga
    11461 tatatagttt caaactatat caaaccctaa ttttttacaa ttatacagac gctttctttt
    11521 ctgttaagat agtttcaaca acaaattttg gaggacacat catgtcaact acaatcatcg
    11581 gtttccctcg tttgggcgaa ttccgtgaat taaaatttac aactgaaaaa tactttagaa
    11641 aagaaatctc agaagaagaa cttttagcag cagcaaaaga cttgcgtgct aaacactgga
    11701 acattgtcaa agaaaaaggc atcactgaaa ttccatcaaa tgacttttct cactatgata
    11761 acttcctaga tgcggctttc cttttcaacg tggtgcctgc atccgttcaa aacttggact
    11821 tgtctgacct tgagcgctac ttcgctttgg gacgtggtta ccagggagaa aaaggggacg
    11881 ttcgcgccct tccaatgaag aaatggttca acactaacta ccactacatc gttcctaaat
    11941 ttgaaaaaga cactcaagta aaattggctg gtcacaagat tttcgatgag ttccaagaag
    12001 caaaagaact tggattgaac actcgtcctg ttcttgtagg tcccttcact ttccttcaat
    12061 tgtcagactt tgaagaaggc gtgaaagcag acgacttcgt agatagctta gtagttgctt
    12121 accaagaagt ttttgctaaa ttggctgaac ttggtgcgac tcgcatccaa ttggatgaag
    12181 cggctcttgt aaaagacttg acagctgaag aaaaagctct cttcttgaac ctttacaaca
    12241 aactcttggc tgacaaaaaa ggtcttgaag tcttgcttca aacttatttc ggtgatgttc
    12301 gtgacgtata cgctgacctt gtaaacttac cagtagatgc tatcggtctt gactttgttg
    12361 aaggtaagaa aactcttgaa ctcgttaaag gtggcttccc agctgacaag actctctatg
    12421 caggtattgt caatggtaaa aacatctggc gtaacaacta cgaaaagagc ttggctgttc
    12481 ttgagcaaat cccagctgaa aacatcgttt tgacaagctc ttgctcactt cttcatgtgc
    12541 catttacaac tgctaatgaa gaatttgaac cagcactctt gaaccacttt gcctttgcag
    12601 ttgaaaaatt ggatgaaatc cgtgacttgg atgctatccg caatggtcaa ggttcagaag
    12661 ctcttgcagc caacaaagaa ctctttgcga ctgagcgtgt tggtgaaaat gctgaacttc
    12721 gtgcgcgtat cgctggcttg acagacgcag actacactcg tttgccagcc tttgcagaac
    12781 gtgaagctat ccaagaagaa gcttttaaac ttccagctct tccaacaaca acgattggtt
    12841 cattccctca aacaaaagaa gttcgtgcca aacgtttggc ttaccgtaaa ggtgaattgt
    12901 ctcaaaaaga gtacgacgct ttccttgctg aaacgattga cgaatggatc aagtggcaag
    12961 aagatattga ctttgatgtc cttgttcacg gtgaatttga gcgtaatgac atggttgagt
    13021 acttcggtca aaacttgtca ggatacctct tctctaaaaa tggatgggta caatcatacg
    13081 gtatgcgtgg ggtaaaacca ccaatcatct ggggtgatgt cactcgtctt aaccctatca
    13141 ctgttaaatg gtctagctat gcacaaagtc gtacaaacaa acctgttaaa ggtatgttga
    13201 ctggacctgt taccatcctc aactggtcat tcccacgtga agacatctct atcaaggatt
    13261 ctactcttca aatcgccctt gctatcaagg atgaagtgct tgaccttgaa gctgctggtg
    13321 tgaaaatcat ccaaattgat gaggctgctc ttcgtgaaaa attgccactc cgtcgtagtg
    13381 actggtacga agattacctt gactgggcaa ttcctgcctt ccgcttggta cactcaacag
    13441 tagcgtcaga cacacaaatc cacactcaca tgtgttactc agaatttaca gatatcatcc
    13501 cagctatcga taacatggat gcagacgtta tttcctttga agccagccgt tcaaaccttg
    13561 aaatcttgga cgaactcaaa gcgaaaaact tccaaacaga agtgggacct ggggtttacg
    13621 atatccactc acctcgtgta ccaaatgaag gcgaaatcga caacacaatc gaagccatcc
    13681 ttgctaaagt gccaagcaag aaagtttgga tcaaccctga ctgtggtttg aaaacacgtg
    13741 gtatcccaga aacaaaagaa agcttgatcc gccttgttga agcagctaaa gctgcgcgtg
    13801 agaaattgta agattggatt tctctccata cagtggttgt tcaaaaagaa atcaactaga
    13861 aaaggttatt acatatgtca tgccaaacac cgtcactctc atttgaagtg ttccctccaa
    13921 acccagccgt gggtaatgat aacattattt tagccttgca ggatatgcag gagttggctc
    13981 cccattttat cagtgtaact gccagcaata ataaatttaa tatcaaggaa acgacggttc
    14041 gtttggctga ctttatccaa aatgacttgg cgattccgac cattgcccac ttgccagcta
    14101 tttatctaac taaggacaag gttgctgaaa ctattgctga cttggacaaa gttggggtgc
    14161 agaaaatctt ggctcttcgt ggggatatta ttccagacgt ggaaccacaa aaggatttcc
    14221 gctatgcaac cgacttgatt gagcttatca aggaacaagc ccctcacttt gatattattg
    14281 gagcttgcta tccagaaggg catccagatt cgccaaatca gatttcagat attcaaaatc
    14341 ttaagaagaa agtggatgca ggctgttcga gcctcgtaac tcagctcttc tttgacaatg
    14401 agcacttcta tgattttcag gacaagtgca tcttggctgg gattgatgtt cccattcatg
    14461 caggaattat gccaattctg aatcgaaatc aggctctccg actcttgaag acttgtgaga
    14521 atatccatct tccacgcaaa tttaaagcca tcttagacaa gtatgagcat gaccctgagt
    14581 cgctcagagc agcaggactt gcctatgcag tggaccaaat cgtagacttg gtaactcagg
    14641 atgttgccgg tgtgcatctc tatacgatga ataatgctga tacagcaaaa tacatccatc
    14701 aagcaaccca tgccttgttt aatcaccagt ctctaggata ataaaagcaa accattcttc
    14761 tcaggtgagg ggaatggttc ctttttaatg gtaaagacct cactttttaa gaaaaatatg
    14821 ataaaataaa ttctgtacgt acttgataca aagatgaagg tattaaataa tacaatgcat
    14881 ttaaactgta agatttaacg acacgagtga gtcaaatcga tgttatttga cgagagagtt
    14941 agtaaagcat ttagctaatc gcccgatagc gattagcgtg aaagctttag atactttagt
    15001 attaaacctt tctaatgatg tatcttgaaa actgaacttg cctacaactc tgtggaaaaa
    15061 gataaatctc cctaggagca gtcgctccgt cgttcgattt cctatcttcc tttgagttgc
    15121 ttgacggctt ggtatcttga tgacttgaat tttggtctca tttcttagga aaaaagataa
    15181 gcttcctagc actcgtcgag tgcgaagtca ccttcctatt tttctacaga aatgttcggc
    15241 aagccgaacc gtccaaaata tcttgtgtaa ttgaacacgg ccgaaaagct gtgtaaaaaa
    15301 gataaactgt cttgtcttca tcgaagactt cgtcagtttc ctatttttac tttgcttttg
    15361 acgtccttgg tatcttgatc tttgtaggca aggcgtataa tttcatcaat ccaaagggga
    15421 ttaaaatggc aaaacaagtg tttcaaacga cttttgcggg tcgtgagtta attgtagaga
    15481 ctggtcaggt tgctaagcaa gcaaatggat ctgttgtcgt acgttacggt gagtcaactg
    15541 tcttgactgc tgccgttatg tctaagaaaa tggcaactgg ggatttcttc ccactccaag
    15601 tcaactacga agaaaaaatg tatgcggctg ggaagtttcc tggtggcttt atgaaacgtg
    15661 aaggacgtcc ttcaacagat gcgaccttga cagcgcgttt gattgaccgt ccgattcgtc
    15721 ctatgtttgc ggaaggtttc cgtaatgaag tccaagtcat caatacagtg ctttcttatg
    15781 atgaaaatgc atctgcacca atggctgcta tgtttggttc atctttggca ctgtctattt
    15841 cagatattcc atttgacgga ccaattgctg gggtacaagt gggatatgta gatggccaaa
    15901 tcatcatcaa cccaagtcaa gaacaagcag agcaatctct tcttgaattg acagtagctg
    15961 gaaccaagca cgctatcaac atggtagagt ctggtgccaa agaattgtca gaagaaatca
    16021 tgttggaagc gcttcttaaa gggcacgaag ctgtcaaaga attgattgcc ttccaagaag
    16081 aaatcgttgc tgctgtcggt aaagaaaaag cagaagtgga attgcttcac gtggatgctg
    16141 aattgcaagc tgaaatcatt gcagcctaca acagtgacct ccaaaaggca gttcaagtag
    16201 aagagaaatt ggcccgtgaa gctgcaactc aagcagtgaa agaccaagtg actgccgttt
    16261 acgaagaaaa atatgcggac cacgaagaat ttgaccgtat tatgcgtgat gtggctgaaa
    16321 tcttggaaca aatggaacac gcagaagtgc gacgtttaat tacagaagac aaggtgcgtc
    16381 ctgatggtcg taaggtcgat gaaatccgtc ctttggatgc ggttgttgac ttccttcctc
    16441 gtgtacatgg ttcaggtctc tttactcgtg ggcaaactca agctctttca gtcttgacct
    16501 tggctccgat gggagaaact caaatcattg atggtttgga tccagagtac aagaaacgct
    16561 ttatgcacca ctataacttc cctcaatatt ctgtagggga aacaggtcgt tacggtgcgc
    16621 caggtcgtcg tgaaatcggt cacggtgctc ttggtgagcg tgctcttgct caagtcttgc
    16681 caagcttgga agaattccca tacgctatcc gtctagtagc agaagttttg gaatcaaacg
    16741 gttcttcatc tcaagcttct atctgtgcgg gaactcttgc ccttatggct ggtggtgtgc
    16801 caatcaaggc gccagtagct ggtattgcta tgggacttat ctcagatgga aataactaca
    16861 cagtattgac agatatccaa ggtttggaag atcactttgg agatatggac ttcaaggttg
    16921 caggtactcg tgatgggatt acagcccttc aaatggatat caagattcaa gggattactg
    16981 cagaaatctt gacggaggct cttgctcaag ccaagaaagc gcgttttgaa atccttgatg
    17041 tcattgaagc aaccattcca gaagttcgtc cagaattggc tccaactgct ccgaaaattg
    17101 atacgatcaa gattgatgtg gacaagatta agattgtcat cggtaagggt ggagaaacca
    17161 tcgacaagat tattgctgaa acaggtgtta agattgatat agacgaagaa ggaaatgtgt
    17221 ctatctactc tagtgaccaa gatgctatta accgtgccaa agaaattatt gctggtttgg
    17281 ttcgtgaagc caaagtggat gaagtttacc gtgctaaagt cgttcgtatc gagaaatttg
    17341 gtgcctttgt taacctcttt gataagacag atgcccttgt tcatatctct gagatggctt
    17401 ggactcgtac caatcgtgta gaggatttgg tagaaatcgg ggatgaagtt gatgttaagg
    17461 ttatcaagat tgatgaaaaa ggccgtatcg atgcttctat gaaggctctt ctacctcgtc
    17521 cgccaaaacc tgagcatgat gaaaaaggtg aaaagtctga gcgccctcac cgcccacgtc
    17581 atcacaagga tcacaaacct aagaaagaat ttacagaaac accaaaagat tcagaataag
    17641 aaaaggagaa atgtatgggg tggtggcgcg aaaccattga tatcgtaaaa gaaaatgatc
    17701 cagcggcccg caccactttg gaggttttgc tgacttatcc aggtgtcaag gccttggcgg
    17761 cccaccgtct ctcgcatttt ctctggaagc acagcttcaa actcttagct cgtatgcaca
    17821 gtcagttttg gcgcttttgg actcagattg agattcatcc aggagcccag attgattcag
    17881 gtgtctttat tgaccatggt tctggtctgg tgattggaga gacagcgatt gttgaaaaag
    17941 gcgttcttct ctatcacgga gtgactcttg ggggaacagg gaaagactgt ggcaaacgcc
    18001 atccgactgt acgaaaggga gccctcatat cagcccatgc ccaagttatc ggacctgtgg
    18061 aaattggtga aaatgccaag gtcggtgctg cagcagttgt cgtagcagat gtacctagtg
    18121 atgtgacggt tgtcggtatt ccggccaaga ttgtccgtct tcatggtaag aaagatgagc
    18181 ctgttattca cgcagtcgaa gaaaaacgag agtattatgt caataaactc gagcaggcta
    18241 aagatgccag tcacagatcg tctggtttgt agaggatacc tatatgattc aagcaagaaa
    18301 caagttaagc caagaggagc tatctgaggc gaaaaaagta attaactgtt gccaaaacta
    18361 tgacggtacc tatcgcgatc cctatctctc taacatgctt aattttgacc caaacatgcc
    18421 cgcctttttc ctttattatg aaaaaggcaa acttgttggt ttattaactg tctatgcaga
    18481 tgaccaagat gtagaagtga cgatactggt tcatccaggt catcgccgtc aggggattgc
    18541 gcgtgcattg tttactagtt ttgagagaga aacagcttct ttccctattc ggtcagtcac
    18601 ttttcagaca gaacgtattt ttttagagaa tcatcctgac tttgccagta actggggact
    18661 aatcgaggat gaagagacag aaacttggtt aggtaaggat agaagacctt atccgttagc
    18721 aaatgtttcc catcttgaaa ttttgttagc agatagttcg tatcaggatc aaattagtca
    18781 attaaaattt caggcatttt cagaggaaca tgaatcgaga gaagttgtgg atagatatgt
    18841 cgctgaagct ctgaaagatc cagaaagccg actatatatt ttattaaaag ctggtcaggt
    18901 tattgggact tgcacggttg atttatcgag cgatacgaat tacttctacg gtttagcaat
    18961 atcagaacct gaacgtggga aaggctatgg aagctactta gcaaaatccc ttgtcaacca
    19021 actaattgag caaaatgata aggaatttca gattgcagtg gaagatagca atgtaggtgc
    19081 caaacgtttg tatgaaaaaa ttggctttgt caaacagaca caggtggttt atctgaatga
    19141 gaaaggagca agggattccg aagtgtagag acattcggac tgaaatttac ttgagctctt
    19201 agtttagtga tgaaactaac agttcttgga ttttagcttt cctgattatg atttatgatt
    19261 aaaatctatg acaccatgtc tcgtgatttg cgagaatttg tcccgattga ggacggcaag
    19321 atcaagatgt atgtttgtgg gccaacggtg tacaactata tccacgtggg aaacgcccgt
    19381 tcgacggtag cttttgatac gattcgtcgc tattttgagt accgtgggta taaggttgcc
    19441 tatatttcca attttacaga tgtggatgat aagattatca accgtgccag ggaagaaggc
    19501 atcacgcctc aggaggttgc ggataagtac atcgctgcct ttcgtgagga tgtgacggcc
    19561 ttgggcgtga aacctgcgac tcgccatccg cgtgtagtgg agtttatggc agacatcatc
    19621 cgttttgtgg aagacttgat cgagaaaggc tttgcctatg agagtcaagg ggatgtctat
    19681 ttccgtgtag aaaaatccca caactatgct aaattggcta ataaaacctt ggaagatttg
    19741 gagctaggtg cttcaggtcg taccgatgaa gaaacggctc gtaaggaaaa tcctgtagac
    19801 tttgctctat ggaaatcttc caaaccaggt gagatttctt gggatagtcc ttggggacct
    19861 ggacgtccgg gttggcatat tgagtgttca gtcatgtcga cagagatttt aggtgatacc
    19921 attgatatcc acggtggtgg agctgaccta gagtttccac accacaccaa tgaaattgcc
    19981 caatctgaag ctaaaacagg caaggctttt gctaactact ggatgcacaa tggctttgtc
    20041 aatatcgaca atgtcaaaat gtctaagtcc ttgggtaact tcattacggt acacgatgcc
    20101 cttaaaactc ttgatgggca agtacttcgt ttcttctttg cgacccagca ctaccgtaag
    20161 cctatcaact tcacggaaaa ggcagttcgc gatgccgaga ccaatctcaa gtatctgaag
    20221 aatacttacg aacaaccatt tacaggaaac gtggatgccc aagagttaca aaactttaaa
    20281 gataagtttg tagcagctat ggatgaagat tttaatgctg ccaacggtat cacagttgtc
    20341 tttgaaatgg ccaaatggat caactcaggg aactatgatg caagtgtcaa gcaagctctt
    20401 gcagatatgt tagaaatttt tggaattgtc tttgttgagg aagttttgga tgcagagatt
    20461 gaagacttga ttcaaaaacg ccaagaggcg cgtgccaatc gtgactttgc gacagcagac
    20521 caaatccgtg accaattggt tactcaagga attaagctcc ttgataccaa ggatggagtg
    20581 aggtggacac gtgattgatg tcaatctcat taacgggatt gcgctagcct ttgaggggga
    20641 tgcggtgtat tctatgtata ttcgccgtca cctcatcctc aaaggtatga ccaaacccaa
    20701 taaactccat caagaagcaa ccaagtatgt gtcagccaag gctcaggctc gcctgattgc
    20761 tctcatgttg gaggagcagg tcctaacgga aaaagaagaa gaaatctaca aacgtggccg
    20821 caataccaat agccacacaa aggctaaaaa tgcagatgtc gtgacttatc gtatgtccac
    20881 gggatttgaa gcggttatgg gctatctcca tatgactgag aatctggaac gtcttgagag
    20941 tttggtttca tggtgcatcc aaaaagtgga gggctagaac atgagggaaa aagaactaca
    21001 agactggttt cctgaggctc ggatttcaga ccaaccagta gagaaagagg gctatctcac
    21061 gctcccttta gcttctcagc agtggatttt gctggaggaa gctgggctca gcgagcgtga
    21121 aaagcagttg gttgcccttt tgacccagca ggagcaggct cgttcgctaa acccttggta
    21181 ttcctatctg gttgaaggca agggacaggc accgcaagtt tttaaaaaga ttcagttggt
    21241 ttattgccat ctttcttatt ttcagcagga aaatctgact tcttggctag atatgatgcg
    21301 gactcttttt ccgaattgtc agacagtgct acaggtcgga gctcaggatt atgttttcgt
    21361 gcttcaacaa gacaaataca cttctgtaag agatatttta agtgatacga ttgaagcggt
    21421 tgagtatgat tttggacttc gtctttctat catgttgggt caggtttggt ctcagacagg
    21481 acatcaagcc ctatcagact taatcaaagc tgagcgggat ttgttcaaga catggtggcg
    21541 tcagggtcac caaggtgttc atactttttc tcagctctat ctttggagta tgggagaaag
    21601 actcgtggac ttgaagccaa ttaaagaatg tctacaccag atgattttgg atcaagatca
    21661 gattcaggaa atcattctct ctctttggga aaatagtgct gttctcacta aaacagccca
    21721 gcaactctat ctgcaccgca attctctcca atacaagatt gataaatggg aagagttgac
    21781 agggcttcag ttgaaagagt tgaccgacct gaccttgtgt tatcaattga ttttaggttc
    21841 tttgtcaact atagttggtt tgtaaagaag ttaatatttg gagaagagga ttgccatctt
    21901 ctccattttt atgtgcagag ttatagtggc ttgatgctgg gaaagtacac tgtgactgct
    21961 aaaacattcc tagaagctgc tttgatttcc ctaatctatt tatgcaaatt ttatgttatt
    22021 ttactataac agttgttgct aagccaaata atagtgggga agttcattta gacgtaagca
    22081 ttgaagataa tcagggaggt agtgggtata atttcagttc tgtttcaagt agctcacaaa
    22141 cagctaaata tgaaggaact ggttataata acaattcatc attatatata acgattgata
    22201 aaacgtctga tgcaacagct cttttgaaat taaagttgaa taatgttgat aatcaacctg
    22261 ctactgaagt tcctagttca ggaattactg taaaattaaa tgctaaagat aatgctggaa
    22321 actggacaag tgcttcgaat aaaaaagaag taacagtaaa aattgtttct gctaaaccga
    22381 catatccaga caaaatctta gtgaaaaatc ctgataatat aaaagataca gaaaaaaatg
    22441 ccattattga aaaattgaaa gaggcaaata aaaatcatcc agcaggagct ccaacctttg
    22501 ctaaaggtga aggagagcat gcaaatgata ttgtagcaac ttattcagat ggtacaactt
    22561 attatgtacc gttaaatgat gtgacaaaat atgcgaggta gtggctgtac cactcactta
    22621 ttcacctccc cgtgatttgt agtagtgata ggctttctca ctattattat aaaacaaaat
    22681 aaagatcaca acactttttc attctgtgtt gtgccttgag tgaaacgaaa ggaatgaatt
    22741 ataaatatga aaagtatagt cactagcata gatgagcgct tgcgtactcg cctacgagtg
    22801 attatctgga agcaatggaa gaagaaatcg agacgattat ggggattgct taagttaggg
    22861 gttcctaaat ggatagcaga taaggtatct ggctggggcg accactatca attatagtaa
    22921 aatgaaataa gaataggacg aatcgatcag ggaagtcaaa tcgatttcta acaatatttt
    22981 agaagtagag gtata
//
LOCUS       DAVAGB010000033        22907 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVAGB010000033 DAVAGB010000000
VERSION     DAVAGB010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22907
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.033"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            473..1594
                     /gene="mnmA"
                     /locus_tag="VQO19_001442"
     CDS             473..1594
                     /gene="mnmA"
                     /locus_tag="VQO19_001442"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HET1349689.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKALSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTCDMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1735..2190
                     /locus_tag="VQO19_001443"
     CDS             1735..2190
                     /locus_tag="VQO19_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET1349690.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVREELGVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2200..4113
                     /gene="mnmG"
                     /locus_tag="VQO19_001444"
     CDS             2200..4113
                     /gene="mnmG"
                     /locus_tag="VQO19_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HET1349691.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(4492..6171)
                     /locus_tag="VQO19_001445"
     CDS             complement(4492..6171)
                     /locus_tag="VQO19_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET1349692.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6173..6406)
                     /locus_tag="VQO19_001446"
     CDS             complement(6173..6406)
                     /locus_tag="VQO19_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HET1349693.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDTSSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6686..6901
                     /locus_tag="VQO19_001447"
     CDS             6686..6901
                     /locus_tag="VQO19_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349694.1"
                     /translation="MYNLFAFAIGARLVAFIVFVACVYAGNLLFAKLERRQTKFLWKM
                     TFVTLYSLFLLLVTYVVWFVFYFELNA"
     gene            complement(7224..7376)
                     /gene="cibB"
                     /locus_tag="VQO19_001448"
     CDS             complement(7224..7376)
                     /gene="cibB"
                     /locus_tag="VQO19_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HET1349695.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7378..7563)
                     /gene="cibA"
                     /locus_tag="VQO19_001449"
     CDS             complement(7378..7563)
                     /gene="cibA"
                     /locus_tag="VQO19_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HET1349696.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKVIAGG
                     TALIGSGLAAGYFLGGD"
     gene            7742..8425
                     /gene="tsaB"
                     /locus_tag="VQO19_001450"
     CDS             7742..8425
                     /gene="tsaB"
                     /locus_tag="VQO19_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HET1349697.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8422..8859
                     /gene="rimI"
                     /locus_tag="VQO19_001451"
     CDS             8422..8859
                     /gene="rimI"
                     /locus_tag="VQO19_001451"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HET1349698.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQETLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            8849..9859
                     /gene="tsaD"
                     /locus_tag="VQO19_001452"
     CDS             8849..9859
                     /gene="tsaD"
                     /locus_tag="VQO19_001452"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HET1349699.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(9899..11205)
                     /locus_tag="VQO19_001453"
                     /pseudo
     CDS             complement(9899..11205)
                     /locus_tag="VQO19_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11481..11832)
                     /locus_tag="VQO19_001454"
                     /pseudo
     CDS             complement(11481..11832)
                     /locus_tag="VQO19_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(11939..12232)
                     /locus_tag="VQO19_001455"
                     /pseudo
     CDS             complement(11939..12232)
                     /locus_tag="VQO19_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            12475..13648
                     /locus_tag="VQO19_001456"
                     /pseudo
     CDS             12475..13648
                     /locus_tag="VQO19_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            13680..14593
                     /locus_tag="VQO19_001457"
                     /pseudo
     CDS             13680..14593
                     /locus_tag="VQO19_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833783.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            14603..16219
                     /locus_tag="VQO19_001458"
     CDS             14603..16219
                     /locus_tag="VQO19_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1349700.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            16684..16919
                     /locus_tag="VQO19_001459"
                     /pseudo
     CDS             16684..16919
                     /locus_tag="VQO19_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816181.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            16931..17680
                     /locus_tag="VQO19_001460"
     CDS             16931..17680
                     /locus_tag="VQO19_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HET1349701.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPCVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            17693..18866
                     /locus_tag="VQO19_001461"
                     /pseudo
     CDS             17693..18866
                     /locus_tag="VQO19_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
     gene            19261..20124
                     /locus_tag="VQO19_001462"
     CDS             19261..20124
                     /locus_tag="VQO19_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET1349702.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRKVVDRFAHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKRYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNILSELMERKLFLYIPIFE
                     AELESMLRPYDVFEKVSWQFLKKMSVFLQTKGSNQKEIERFTQSLQVLENPQLTSLFE
                     LRFQQYKELID"
     gene            20410..20610
                     /locus_tag="VQO19_001463"
     CDS             20410..20610
                     /locus_tag="VQO19_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HET1349703.1"
                     /translation="MLNLQFAETMELTEAELETVYGGELGYNAVIPGGSWGGLGTSWS
                     ITNFWKKNFNDRPDFDSDRRRY"
     gene            20678..21343
                     /locus_tag="VQO19_001464"
     CDS             20678..21343
                     /locus_tag="VQO19_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET1349704.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            21415..22641
                     /locus_tag="VQO19_001465"
     CDS             21415..22641
                     /locus_tag="VQO19_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET1349705.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLKHTISIKTALYASLVTQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
BASE COUNT         7008 a         3897 c         4866 g         7136 t
ORIGIN      
        1 ggcttaggtg cccttgcagt caacacaact gtagatggct ataaagtcaa tgccaatggt
       61 gaatgggttt aagccgatta aattaaatca tgttaagaac atttgacatt ttaattttga
      121 aacaaagata aggttcgatt gaatagattt atgttcgtat tctttaggta cctatcttat
      181 gatttcagga aatgtcatta aaaaaacgac tccttttctc taacttgaaa aatagattag
      241 agaaaatggg ttgttttatt tattatagtt atttgaatga agataagaat aaggtatact
      301 cacatcattc acataatctg tatattgact ataagtttta aaaaacaatt tttaagctct
      361 tccttgtctt ctctaaccaa gcgtgttata atgaatactg ctcaagcgac cttcaatcgt
      421 gaagcacaca cgaccttcaa tcgtgaataa acgaatagat gggagactta ccatgagtga
      481 taactctaaa acacgtgttg tcgtggggat gagtggtggt gttgattcgt cggtgacggc
      541 tcttttgctc aaggagcagg gctacgatgt gatcggtatc ttcatgaaga actgggatga
      601 cacagatgaa aacggcgtct gtacggcgac cgaagattac aaggatgtgg ttgcggtggc
      661 agaccagatt ggcattccct actactctgt caattttgaa aaagagtact gggaccgcgt
      721 ttttgagtat ttcctagcgg aataccgtgc agggcgcacg ccaaatccgg acgttatgtg
      781 caacaaggaa atcaagttca aggccttttt ggactatgcc ataaccttgg gggcagacta
      841 tgtagcgact gggcattatg ctcgagtggc gcgtgatgag gatggtaccg ttcacatgct
      901 tcgtggcgtg gacaatggca aggatcagac ctatttcctc agccaacttt cgcaagaaca
      961 acttcaaaaa accatgttcc cactaggaca tttggaaaag cctgaagttc gaaaactagc
     1021 agaagaagca ggtctttcga ctgctaagaa gaaagactcg acagggattt gctttatcgg
     1081 agaaaagaac tttaaaaact ttctcagcaa ctacctgcca gctcagcctg gtcgcatgat
     1141 gactgtggat ggtcgcgata tgggcgagca tgcaggtctg atgtactata cgattggtca
     1201 gcgtggcggg cttggtatcg gtgggcaaca cggtggtgac aatgcccctt ggttcgttgt
     1261 cggaaaagct ctaagcaaga atattctcta tgtaggacaa ggattctacc atgattcgct
     1321 catgtcaacc agcctagagg ctagccaagt ccactttact tgtgatatgc ccgaggagtt
     1381 tacgctagaa tgtacggcta aattccgtta ccgtcagcct gactctaagg tgaccgtcca
     1441 tgtcaaagga gacaaggcag aggtcatctt tgcggaacca caacgcgcca ttacaccagg
     1501 acaggcagtt gtcttttacg atggcgaaga gtgtctaggt ggcggtttga ttgacaatgc
     1561 ttaccgcgat ggacaagttt gtcagtacat ttagattgac aaattttctc aatttgctac
     1621 aataataaca gcaatagaaa tgatggtcaa agctcatgga tgttgcaggc ttttttgtcc
     1681 tgcacttctt tgtagttttg actgtttttg tgtcgtttaa gggaaaggac aagaatgact
     1741 caacaagact ttcggacaaa agtagacaat acggtttttg gtgttcgggc gacagccttg
     1801 attgtccaaa atcacaagct tctagttacc aaagacaagg gcaagtatta cactattgga
     1861 ggtgcgattc aagtcaatga aagcacggaa gacgcggtag tccgtgaagt gagggaagaa
     1921 ctgggtgtta aagctcaagc tgggcagcta gcttttgtgg ttgaaaatcg ttttgaagtg
     1981 gacggcgttt cctatcacaa tatcgagttt cattatctgg tggatttgct tgaagatgcc
     2041 ccgttgacca tgcaggaaga tgagaaaagg cagccctgtg agtggattga cttggataag
     2101 cttgaggata tccagctagt tccagccttt ttaaaaacgg ccctaccaga ttgggaaggc
     2161 caactaagac acattcatct tgaggaatag gagagaaaca tgacttatca ttttactgaa
     2221 gaatacgata ttattgtaat tggtgcggga cacgctgggg ttgaggcttc cttggccgct
     2281 agccgtatgg gctgtaaggt cctgcttgcg accatcaata ttgaaatgct ggctttcatg
     2341 ccttgtaatc cctctatcgg tggttctgcc aaggggattg tcgtgcgtga agtcgatgcc
     2401 ctcggtggcg agatggccaa gactattgac aagacttaca tccagatgaa gatgctcaac
     2461 acagggaagg ggccagctgt ccgtgctctt cgtgcgcagg ctgacaagga actttactct
     2521 aaggagatgc gcaagacagt tgaaaatcaa gaaaatctga cccttcgtca aaccatgatt
     2581 gatgagattt tggtggaaga tggcaaggtt gtcggtgtgc gtacagccac ccatcaagaa
     2641 tatgctgcta aggctgttat tgtgacgaca gggactgctc tccgtgggga aattatcatc
     2701 ggagacctca agtactcatc aggtcctaac cacagcttgg cttctattaa cctagctgac
     2761 aatctcaagg aactgggcct cgaaatcggt cgtttcaaga caggaacccc tccacgtgtc
     2821 aaggcttctt ctatcaatta cgatgtgaca gaaatccaac caggagatga agcgcctaat
     2881 cacttctcat acacttcacg tgatgaggat tatgtcaagg accaagtgcc atgctggttg
     2941 acctacacca atggtaccag tcatgagatt atccaaaaca acctccaccg tgcgcctatg
     3001 tttacaggtg tggtcaaggg agtggggcct cgttactgtc cgtcgattga agacaagatt
     3061 gtgcgctttg cggacaagga acgccaccaa ctcttccttg agccagaagg acgtaataca
     3121 gaggaagtct atgtgcaagg cctctcaacc agtctacctg aggatgtcca gcgtgacttg
     3181 gttcattcca tcaaaggttt ggaaaatgca gagatgatgc gaacaggtta tgccattgag
     3241 tacgacatgg tcttgcctca tcagttgcgt gcgactttgg aaaccaagaa aatctcaggt
     3301 ctcttcactg ctggtcagac aaatggaaca tcaggttatg aagaagctgc tggccaaggg
     3361 attatcgcgg gtatcaatgc ggctttgaaa atccaaggca agcctgaatt gattctaaaa
     3421 cgaagtgacg gttatatcgg ggtgatgatc gacgacttgg tgaccaaggg aaccattgaa
     3481 ccttaccgtc tcttgaccag tcgtgctgaa taccgtctta ttcttcgcca tgacaatgct
     3541 gatatgcgct tgactgagat gggacgcgag attggccttg tggacgatga acgctgggct
     3601 cgttttgaaa tcaagaaaaa tcaatttgat aatgagatga aacgcctaga cagtatcaaa
     3661 ctcaagccag tcaaggaaac caatgctaag gttgaggaaa tgggcttcaa gccgttgaca
     3721 gatgcggtga cagccaagga attccttcgc cgtccagaag tttcttacca agatgtggtg
     3781 gccttcatcg gaccagctgc agaagacttg gatgacaaga ttatcgaatt gattgaaaca
     3841 gaaatcaagt atgaaggcta tatttccaaa gccatggacc aggttgccaa gatgaaacgc
     3901 atggaagaaa aacgcattcc ggccaatatc gactgggatg acattgattc tatcgcaacc
     3961 gaagcccgtc agaagttcaa actcatcaat ccagaaacca tcggccaagc cagccgtatt
     4021 tcgggagtaa acccagcaga tatttctatt ttgatggtgt atctggaagg taaaaatcgt
     4081 agtatttcta aaactcttca aaaatcaaaa tgatacgtcg tcggcttctt acgaatgagt
     4141 tcaaagcttg gctttgattc atctccagcc tcccatagtt tcccgaacta tgggagctaa
     4201 ctcaagttat gctttcgctt agccttctag tctgattttc attgagtttt aatctcaaaa
     4261 gaaagcatag agaaaaacag ctccgaagac ggggctgttt tgttgacttg tactcaatga
     4321 aaatcaaaga gcaaactagg aagctagccg taggttgctc aaagcactgc tttgaggttg
     4381 tagatagaac tgacgaagtc agctcaaaac acagttttga ggttgtggat agaattgacg
     4441 aagtcagtaa catatatacg gcaaggcgaa gctgacgtgg tttgaagagt attattcttc
     4501 atctggtgtg aggatcatcg ggatgatgat cggttcacgt tcggtatttt catagaggaa
     4561 ggggcgaata gcgttgacaa tggcaccatt gacagattgc acgctagcat ccttattttt
     4621 cagtgcgata cgaatggcat tgaagaggat acgctggctt tggcgaatca agtcgccaga
     4681 ctctctcatg tagacaaagc ctcggctgag gatgtctgga ccagatagaa tcatctgcga
     4741 tttgaagtca acagttgcga ctgccagaac gacaccgtct tcagatagat cgcgacgatc
     4801 tttgaggaca gctgcgccaa tttcaccgat acgatttcca tcgacataga tatcttgggc
     4861 gttgaaatga cctgcgatac gagctgagtc agcagtaagg gcaagcacat cgccattgct
     4921 catgataaag atattgtcct tctcaacacc agtatccact gctagtccag cgtggacttt
     4981 ttgcatgcgg tattcaccgt ggacaggcat gaagtatttt ggcttaatca agcagagcat
     5041 gagtttttgc tcttgctgac caccgtgtcc agatgtatgg atattgttca ctttaccgtg
     5101 gataacttcg acaccagctt cagaaatgat gttaatcagc ttgttgacgc tagtagtgtt
     5161 tccagggatg ggactagaag agaagataac ggtatcacct ggttgtaatt gtacttgacg
     5221 gtgggttccg ttggcgatac gagagagggc tgccataggc tcaccctgac tacctgtaca
     5281 gaggataaga acttctcctg caggataatc tttgatttca tttggctcga taaaggttcc
     5341 cttaggggct ttgatgtagc caagatcgat tccgttgaca atggcctttt ccatagaacg
     5401 accaaagacc gcaatcttgc gtccagtctt aacagcagct tctgttgcct gctggagacg
     5461 gaagatattt gaggcaaagg atgcaaagat gatacgtcct tcaatacctt ggataatctt
     5521 cataatggac tgaccaacga ctttttcaga gttggtaaag gttggtactt ccgcatttgt
     5581 cgagtcagac aggagacaga gcacgccttc ttcaccaagc gcagccatac gatgcaagtc
     5641 cgcaggttct ccaactggag taaagtcgaa cttaaagtca cccgtacaga cgattttccc
     5701 ttgaggagta tgaatgacaa tccccaaagg ctctggaata gagtgagtcg ttctaaagaa
     5761 agttgccttg agatttttaa aggtcaactc ggtgttgtgg ttgatttcgt aaagtttggc
     5821 gttgcgcaag aggccgtgtt cttcgagttt cccacggatc aaagccaagg caagcggtcc
     5881 agcgtagata gggacatttg cttgcttgag taggaacgga atcccaccaa tgtggtcctc
     5941 gtgtccgtgt gtgattaaaa cagccttgac gcggtcgata ttgtccacga tgtaagagta
     6001 gtcaggaatg acatagtcga taccaagcaa gtcatcttct gggaatttaa tcccagcatc
     6061 gacgatgata atctcgtctt ggtattcaat tccgtaagtg tttttcccga tttctcctag
     6121 accaccgatg gcaaaaacgc cgacttcttc aggtttaaga gtgtaggcca tattagaact
     6181 ccgtaatttc gaaggcgcca gtttcttttt cgtaatcgag caatttgtca gacaagagtt
     6241 cgatatattc gatattgtac tctgggcgat tttcttcgac aagttggcga gcagtgatac
     6301 ggccctcaag ttctgagctg gtatcgatat ctaagtaaag cgcgcgtgtt gtttcacggc
     6361 gtgggctacg ttcttttgtt tcttgataaa aaactttgta aatcatatag ttcctttcta
     6421 tttacaggtc agcttattcc aaacttttag cagatatttg cttgatttca ttccattttg
     6481 tgtctagatt gaccttgatt cgttacaatt atttcaatta taccacaaaa tgaaaaatta
     6541 gtaaaagacg gaaacgagaa agttagggga cgatttcttt ggtaatcgtt tgcaaaaaca
     6601 aagaaaatgt attatgttga taacggaagt gaaatttatt gcttgtcata attccatata
     6661 gattttaagt caaggaggtt gccctatgta taacttattt gcttttgcta tcggagctcg
     6721 cttggtagct tttattgttt ttgttgcttg cgtttatgcg gggaatcttc tatttgccaa
     6781 actggaacga cgacaaacca agttcttgtg gaaaatgacc tttgtgactc tctactcgct
     6841 ttttctcctc ctcgtgacct atgtcgtttg gtttgtattt tactttgaat taaatgctta
     6901 gatgccctgc ttatgctggg gttttttgtt tggggatgta gagatagtag atttacgaca
     6961 cgaaaattcc accccatcta tcaagatgag gtggtctttg catttttcta acatgacatg
     7021 acaatggaat tttcaaagct tattattttt atgggagtca ttgttctgat caaaaataga
     7081 gttgaagcat aaaaataaaa caatacaaac agataaatcg aatggtaaag ggatggtagt
     7141 aatgttcaaa tcattgagaa tgctgagcaa actgtaagag atgaagacaa taaaatttat
     7201 ccttctaaaa atgtgtttct tatctagcat gacttaccaa actttttacg aaggtctttt
     7261 ccaatggtat aacctgccat aaataaagcg ataccaacac cgacaccaaa gccacccttg
     7321 atttcttgca attccttatt agaaatttca cgataattgt tcaaatcttt catcatatta
     7381 atctcctcct aaaaaataac cagctgccaa accagaacct ataagtgctg ttccacctgc
     7441 aataaccttc caagatactg ctactccaaa gataactaag ggagcgagac cgccatcaat
     7501 atctgataat tcattttcag ataaggataa aaattgattg tcaagaatgt caaaatttgt
     7561 cattgaactt tcctcctttt ttcttgttca cttttatatt cggaaaagaa aaggaaaatt
     7621 gagcattttt tttaaattat ttttagttaa gtgagggcac tcttgtctgg gggcaaagaa
     7681 aattcccatg tgccagcttt tgtagtataa tagtaagcag acaaaaagat aggaatgtgt
     7741 tatgaaagta ttagcttttg atacgtccag caaggctctt tctctggcta ttttagagga
     7801 taagcaggtt cttgccgaga cgacgattaa tattaagaaa aatcacagta ttacccttat
     7861 gcctgccatc gattttttga tggcaagttt ggattggaca cccaaggact tggaccgaat
     7921 cgtggtagct gaagggccgg gtagctatac aggcttacga atcgcggtag ccactgccaa
     7981 aactctggct tatactctga atatcgagtt ggttggtatg tcgagtctct tggctctggt
     8041 gccctaccaa caagaaggtt tgtttgtccc cttgatggat gcgcgtcgca ataatgttta
     8101 tgcaggattt tatgaaaatg ccaaacctgt catggcagaa gcacatctgc cttttgagcg
     8161 agtcattgag ctaatcaagg gcgctagtca ggtaaccttt gtcggagaag ttggcccctt
     8221 tgttgagcag attcaaaaac acttgccaag gactgattac aaagaaacat tgcccaatgc
     8281 agctaatcta gctcttttgg cctgggacaa ggaagcagac tccttgcatg attttgtgcc
     8341 aaattacctc aaacgtgttg aggcagagga aaactggctc aagaaccata ccgagtctgg
     8401 tgagtcctac attaaacgcc tatgatagaa atcaagcgaa ttcaacaaca gcctgaccta
     8461 gctcaagcca tctacgctgt tatggcagct gtttacctag tcagtccttg gactctggag
     8521 caaatccaag cagatctgtc ccaagaccag acttggtatg cattggctta tgatggggca
     8581 gaagtgattg gatttctagc tgtgcaggag actctctttg aagcagaagt cctgcaaatc
     8641 gctgtcaaag gagcttatca gggtcaggga attgcgtcag ccttgtttgc tcaattgccg
     8701 acagataagg agattttcct cgaagtcaga aagtcaaatc aacgagcgca agcattttac
     8761 aagaaagaaa aaatggcggt catcgctgag cgaaaggcct actaccatga cccagtcgag
     8821 gacgccatta tcatgaagag agaaatagat gaaggataga tatattttag catttgagac
     8881 atcctgtgat gagaccagtg tcgccgtctt gaaaaacgac gatgagctct tgtccaatgt
     8941 cattgctagt caaattgaga gtcacaaacg ttttggtggc gtagtgcccg aagtagccag
     9001 tcgtcaccat gtcgaggtca ttacagcctg tatcgaggag gcattggcag aagcagggat
     9061 taccgaagag gacgtgacag ctgttgcggt tacctacgga ccaggcttgg tcggagcctt
     9121 gctagttggt ttgtcagctg ccaaggcctt tgcttgggct cacggacttc cactgattcc
     9181 tgttaatcac atggctgggc acctcatggc agctcagagt gtggagcctt tggagtttcc
     9241 cttgctagcc ctcttggtca gcggcggaca cacagagttg gtttatgttt cggaggcagg
     9301 agattataag attgttgggg aaacccgtga tgatgcggtt ggtgaggctt atgataaggt
     9361 cggccgtgtc atgggcttga cctatcctgc aggtcgtgag attgacgagc tggctcatca
     9421 ggggcaggat atttatgatt tcccccgtgc catgattaag gaagataatc tggagttctc
     9481 cttctcaggt ttgaaatctg cctttatcaa tctttatcac aatgccgagc aaaagggaga
     9541 aagcctgtct acagaagatt tgtgtgcttc cttccaagca gcagttatgg acattctcat
     9601 ggcaaaaacc aagaaggctt tggagaaata tcctgttaaa accctggttg tggcaggtgg
     9661 tgtggcagcc aataaaggtc tcagagaacg cctagcagcc gaaatcacag atgtcaaggt
     9721 tatcatcccc cctctgcgac tctgcggaga caatgcaggt atgattgcct atgccagcgt
     9781 cagcgagtgg aacaaagaaa acttcgcagg ctgggacctc aatgccaaac caagtcttgc
     9841 ctttgatacc atggaataaa gagtggctct ttgtcaagtg tagtgggtag gcgaaaagct
     9901 acaatctgga gagtacgaaa ttcgtactct cttttttgat gttcaaagtc atcaaaatcc
     9961 gttttttaaa attgttaaag ttccggaaac caaaggcttt gcgcttgata accttaatca
    10021 aattattggt cgcttcaagt ttagcgttgg aataaggcag cttaagtgcg ttgataatct
    10081 tatctctatc ccttaaaaaa gtccaaaaga ccgtttgaaa aagcggatga accgttggca
    10141 gttcttgctc aatcaatcca aagaaatggt cggcattctt ctcttgaaaa tgaaagagca
    10201 ggagttgata gagttcgtag tgaacctgta atccctcaga gtaggaaagc agcttatctc
    10261 gtacttcccg atgggttaag tgcattcgaa acgtggactg atagaatcgt ttctgacaga
    10321 gcttgaagct atcctggtgt agtaaatcag tccagtggac tgatttagcc cgagcctaga
    10381 aacgaaaaag cgagggttcc aaaagcgctt gagcgcccga tactccaagg attttcggtc
    10441 aaattggttc atgatttgga ttcgtactcg gttcatagct cggctcagat gttggacaat
    10501 gtggaagcgg tcaagaacaa tcttcgcctt tggaaagagt tgcttagcga gccgataata
    10561 agggctgtac atgtccatgg tgatgacctc gaccagctcc cgaacctctc tctgatagcg
    10621 ttggaaatgg tttcgaatca ccgcatgagt tcgcccgtct aaaattgcga ggatagattt
    10681 ggactcaaaa tcttgggcaa tgaagctcat tttgctcttt ttgaagctat actcatccca
    10741 actcataact tttggcaact tggtccaatc ggtttcaaac ttaaattccc tcagttttcg
    10801 gatgacggtg gaagttgaga ccgccaatct gtgggcaatc tcagtcatag actgcttttc
    10861 aaggaggagc tgagcgattt tttgtctcac catgttggaa atctggcaat ttttcttgac
    10921 aatggatgtt tgagaaacga ccaccttaag gcaattcttg cactgaaagc ggcgcttttt
    10981 gagatgcagt accgtgggta aaccctgaca gtcgagaagc ggaattttag aggctttctg
    11041 gaagtcgtat ttgatcatct tcccttgaca atgaggacaa ggaggagcgg gggaatccaa
    11101 ctttgcctga acgactagat gggtttggta tttcagaaca gacaagattt tgatattttt
    11161 gtcttccaat ccgagcaaat ctgtggtatt cttaagttgt tccatatgga ccctttctaa
    11221 tgagttggtt agacgctttt cattataggt catatggggc tttttttcta caagaaacga
    11281 ccctataatt cctggggtgg gattacccac tacagaaatt atagagccaa agcattccaa
    11341 agtcttgtct gactctggaa tgttttctgt tcacagttgt tttgtaactg cctaataagt
    11401 aaccgcgcta taacgaggta tctaccgaga ttgtcaattc tccagtatac tgttataaaa
    11461 aacaaaactg gaggattttt ttatgtcccc ccatcgtccc atcgactgtt ccgtagctgc
    11521 ccaataacgg agtatagtcg gctgaaacaa gaataggaca aaagtgcctc aagaaaagca
    11581 tcgtaatttg acaatattat tctgagatgt ttttgatgta agcccatatt ttctcaatgg
    11641 gattatactc gggtgaatag gtaggaagtg gtaacagtct atgccctgct ccttacacat
    11701 gttcattctg tgaaaccttg cattgtccat aatgataagg gatggtgtat ctaaagtagg
    11761 tagtaagaat ttttggaagc aagcttcgaa aaagtcactc gtcatcgtat ctttataggt
    11821 catcggagcc atagtatatt gaaacaaaaa agggcattag tacttctata acagtatcgc
    11881 aatctctggt gtgcgttgtc tcgatcttaa ttcaaataat tatatcttct tccagagaga
    11941 ctaactgcct gctcaaggct cgatcatatt cgagataaaa ataggtctca acccctgtct
    12001 cataaatata aataggagtc aggtagctta agtgattcaa ttctttaagg aaccgattta
    12061 ctttttctgg gtcttgttcg cagtaggtac ggctcttttt tagactatat cccatagcct
    12121 ttagagcgta atgaatagtt gttggaggac agttgaattc agcagctatt tcagtcaaat
    12181 aagcatcggg atgagtttca atatagatct ttaatttatc tctatcaact ttttcaatta
    12241 atagtggaag ttttcttaaa gttagtgtgt tgaaacgttt ttatacagtg ctaaaatttg
    12301 aagtgtagtg cagatgtatt tgtaatagta ttatagcaat tctttggaga aggtcgagac
    12361 aagagaaaat aggtatcttt gagatataag catgatttac tataaaatta ttgagttatt
    12421 cataaaaatt tctctatcaa atatcataat gcgtcgttta aggagatggt tacaatgcaa
    12481 tatagttgtg gaaaaataaa tattaatatc cctgatggat atggagacat taaggatata
    12541 gtgttttcgg ctcatattat agttaggtat aataatggac attgtggagg tatagatccg
    12601 catataattg gactttgtaa aaagcagatc agaaggatgt ctctatatcc tattttgata
    12661 atcgtatcta gagattcaaa ggttattgat gattataaaa atttagatat tgcctatgtt
    12721 gattgtactc aatgttcaaa taattttgaa actgccttac acgttaaaaa tattttaaaa
    12781 ttattaaaaa tccaacttat acactgtcat ggctactcaa ctaattattt tttatatatg
    12841 ttaaaaaaac ttgacaagaa tggatttgga aaggttaaga cagtgataac atgccatgga
    12901 tgggttgaat ataacttaaa aaagaaattc ttgacttatt ttgatttttg gacatattct
    12961 atgggagatg cttttatttg tgtatctgaa actatgaaaa aaagattgga gagtataata
    13021 aaaaaataag aagatagttg caataaataa cggaattaat gtatcaaata gcgatttaga
    13081 tgtagtaggt gttcaagact ttaaaaaaga attttgtatt ccaaataaca aaaaaatcat
    13141 ttgttatttg gaaggttgga tccagaaaaa aggccggata gattccttga atttgcagaa
    13201 aaattatttt tagtcagaga agatgtgatt tttattatgg ctggaaatgg tagtatgtgg
    13261 gctgctttga aagaaaaaat ttgccatttg aaatgtagag ataatttcag gttacttggt
    13321 gaaatctatc cagctactat agtttaccaa atatcggatt tattgtatat tccttctgat
    13381 acagaaggaa tacctatgtg tgttttagag tcaatgtcac aaggaactcc ggttttagct
    13441 agtaatgttg gcgggttaag tgaaattatt gaacataggg ttgatggatt tttatttgag
    13501 aaggaagatg ttgagggagt gtgtgcttgt gctaattttt tactcaatga ttctgagtat
    13561 ttgaaatata taggtgagaa tagtaaatca aaaataagaa aacatgagag tatatgatga
    13621 attattagag aagagtagtc atggatagga atatagatta agaattagta agtattataa
    13681 taccaacaca taataggtat gaatctctga ttagagctgt gaaaagttgt ttacatcaaa
    13741 gttataaaaa tatcgaagtt ataattattg atgataatta tagtaatgta aatttaagaa
    13801 ataaaattat ccatcaattt ggctatacca atcatagaat taagttaatt ttaagtaatg
    13861 aagatttagg tgcaactaat gccagaaaca taggtatcaa aaattctaga ggtaagtata
    13921 tatcattttt agacgatgat gatgaatata tgccagatcg aatttttaag ttgatggctt
    13981 gttttaaaaa gagtagaatg aagaatttag ctttagttta tagttatgga ataataattt
    14041 atccaaatgg tacacgagaa gaggagaaga ccgattttgt tggaaatccc ttgtttgttc
    14101 aaatggttca caatatagca ggtacgtcat tttggttgtg taaaaaagag gtgctagaat
    14161 taattaatgg ttttgagaaa atagattcac atcaggacgg tgttgtttta ttaaaactac
    14221 ttgctcaagg ataccaaatt gatatagtgc gagaattctt ggtgaattac tacgctcaca
    14281 gtaaagaaaa cggtatcact ggagtgacac aaaaaacaat taatgcagat gaagaatatt
    14341 ataattactg taggaaatat tttaatttat tgagtttcaa cgagagaata ttggttacaa
    14401 agaaatatta ttctttaaac ataaagcggt tactattaat aggagacaaa tgcaaggctt
    14461 taaaagtaat caagaaggca agagaagaaa aaatttttaa cgaatttctt ttttgaaata
    14521 tatgttatta tatcattttg gctttttcta ttgtatatat gacaactatg ttcaattaaa
    14581 atttagaaag tgagaaacta ttgtgtatac tattataaaa tcaaatataa aaaaatttag
    14641 tttattaacg atatttattg ttgctggtca attattgcta atttatgcag caactattaa
    14701 tgctctggtg ttgaatgaat taattgcgat gaatttagag cggtttttga aattgtcaat
    14761 ctaccaaatg attgtctggt gtgggataat attccttgac tgggtagtga aaaattatca
    14821 ggttgaagtg atccaagagt ttaatctaga gattcgaaat agagttgcca cagacatctc
    14881 taactctacc tatcaagaat ttcatagtaa atcatcagga acatatcttt cgtggctaaa
    14941 taatgatgtt cagactttaa atgatcaggc ttttaaacaa ctttttttag taataaaagg
    15001 aatttctggt actatatttg cagttgtgac tcttaatcac tatcattggt cattgactgt
    15061 agccaccttg ttttcattaa tgattatgct acttgtacca aaaatctttg catcgaaaat
    15121 gcgagaagtt agtctaaatt taactaacca aaatgaagct tttttaaaat ctagtgagac
    15181 tatattgaat ggatttgatg tgttagcgtc cttgaatctt ttatatgtat tgcctaagaa
    15241 aattaaagaa gcaggaattt tattaaagat ggttatacaa agaaagacaa ctgtagaaac
    15301 gttagcaggc gctattagct tctttctcaa tatttttttt cagatatctc tcgttttttt
    15361 aacaggctat cttgcaataa aaggaatagt gaaaattggt actattgaag caataggagc
    15421 actaacaggt gttattttta cagcgctagg tgaattagga ggtcaattat cctctattat
    15481 tggtacgaag cctatttttt taaaattgta ttcaattaat ccaattgagt caaataaaat
    15541 gaatgatatc gaaccaaatg aggtgaatag agattttccg ttatatgaag caaaaaatat
    15601 ttgctataag tatggagata aagaaatatt aaaaaactta aatttttgtt ttcaacgtaa
    15661 tgaaaagtat ttaattttag gtgaaagtgg aagcgggaaa tctacattat taaaattatt
    15721 gaatggcttt ttgagagatt atagtggaga attgcgattc tgcggggatg atataaaaaa
    15781 aacctcctat ttaaatatgg tttcgaatgt tctatatgta gatcaaaaag cttatttgtt
    15841 tgaaggtacg attagagata atattttatt ggaagaaaat tatactgatg aagaaatact
    15901 acagtcttta gagcaagttg gtttgagtgt aaaagatttt cctaataaca ttttagatta
    15961 ttatgttggt gatgatggga gattactgtc aggagggcag aaacaaaaaa ttactttagc
    16021 tagagggcta attagaaata agaaaatagt attaattgac gagggaactt ctgctatcga
    16081 taggagaact tcgttagcga ttgaacgtaa gatattagat agagaggatt tgactgtcat
    16141 tattgttacc catgctccgc atccggaact taaacaatat tttactaaga tatatcaatt
    16201 tccaaaggat tttatttaag aatatagggg agggaaacat gagattctat tgtgaagctt
    16261 atgaggtaat tactgaagag aaaaaagtat cattttttta tgtagatgaa aaacccttaa
    16321 ggtatctgtt atttgactat atatttctac tagttctagc taaaaaaaaa tatcccaatc
    16381 ttatgaactg caccccaaaa gttagattta ttctgtctaa cttttggggt gcagttcatt
    16441 ttgcatagtt ttggcattca tcctagatat ccatataaaa tgtctgagat tgttgaaatg
    16501 tctaaaaaaa tatcaaatct aaacgataaa aaagaatttc acaaaaagaa ctgtgagttg
    16561 aggtttcaag atagtgttct tgataacata aatagtgtcc cgggtacaac tcatttattt
    16621 agttgtttaa atattcaaac attagtaaaa attattttat atatttttcg atacaacagt
    16681 tgtatgaaaa tatttaattt tagagataaa gagcttatct tttttaataa gattgtaaat
    16741 gggctgatac aaaatattga ggagaattta gaggatgata ttgaaaggat attgaaagga
    16801 tattgaaata tttatatata tgtttattta acgaaatatt cattattaag aataaggtga
    16861 atttttttga tgatgtggaa tttaatcaga cacttagtga gtttttagat aaattgtaga
    16921 gggaatggtt atgagtaaca atactaagta tatcttttta tctccacatt tagatgacgc
    16981 aattttttcc tgtggtgatt atatttcaaa attaacttca gaaggagaaa ttgtacttgt
    17041 tattactata ttttctggtt accctttgag ccaacagcta cagccctctg ctaagcaatt
    17101 tcataagttg tgtaaccttg ggaaatatcc gattgaagaa aggaagaaag aagacaggtt
    17161 agcttgtgaa cgtctacaat gtgattttag acacttatcg tactatgaat gtctctatag
    17221 gaaagataga aatggcaatt ttctataccg tcatatctat agtgaattaa aaaatgagga
    17281 cacattaaag aatgatatca taaaagagct gttaatgcat ttagacgaca aatgtgtcgt
    17341 atattgtccg ctttcacttg gtgaccatgt tgatcatgtt tttgtgaata gtattggaag
    17401 ggcgcttgaa tttatgcgtt ataaagtaat atattatgag gacttcccat gtgtaagtga
    17461 tagtagtatg gttagttata tgggaaaaac taaagaatta aaaatgtatc aagaggaact
    17521 tgatgaaaaa cattatattg atagaatatc atcaatattg tgctataaat ctcagatttt
    17581 gataatctgg aaatcagttg aaaaactttt aaacaatatt aaagagttgt atttaaggaa
    17641 tggggcagct tattctatta gattttggat taagaaataa ggaagtagtt ttatgaatat
    17701 agcagtaatt ggtttggggc atgttgggct ggcctacgcg ttactatttg catctaaata
    17761 taaagttgtt gcatatgata tagattctgt aaaaataaat aatttaaaaa aagggcattc
    17821 ttccatctaa aaatgaagag cttatgaagt ttttttgcga gaataactta aatattactt
    17881 tttttgatac attttctgaa attaaaaata atattgatta ttatattatt gcgcttccga
    17941 cagattatga tgagaaaatt ggtagtttta atacatatga aatcgaacaa acggtatcga
    18001 agattctgag ggtaaaacct aatggaaaga ttattttaaa gttaacagtt ccgttcggct
    18061 tttcaaacaa attaaaaagg ctgtttgata caaaaaatat catttttgtc cctgaatttt
    18121 tgagagaagg ttgttctata tatgataatt tatatccaag tcgcatagtt gttggagatg
    18181 agacagttga aggaagaaaa attgcagagt tgttcctttc gattagtact catagtactg
    18241 ccaatattaa aaatgttatg ttagtttctc ctactgaagc agaagcaatt aagctttttt
    18301 ctaacacatt cttagctctc cgtgttgctt tttttaatga actagattct tttgctgaga
    18361 ggagaagttt aaatgctgaa gttgtaataa aaggtgtttg tttagatcca agaattggaa
    18421 aattttataa taatccttct tttggatttg gaggatattg tcttcccaaa gatactaaac
    18481 aattaaaaaa agaatttata gaaataaatg ccccagtgat agaagcgatt gatatttcaa
    18541 acacaaatag aaaacagttc atagttaaac aaatattgga acgaaagcca aagatagtag
    18601 gaatatataa attggggatg aaatataatt cagataatta caaagagtca gctattttaa
    18661 gtataattaa tgaactattg attgtcggta taaaaatttt agtatatgaa ccaaatttaa
    18721 acgttagtat agataacgta atttttgaaa agaattttga actatttaca aaacaaagtg
    18781 atctaattgt tgcaaataga tgggataggg gccttgaagc ttataaagat aaagtttaca
    18841 caagggggat ctggataaga gattaactat tgatattaaa aaggcaataa tttataaaat
    18901 ttgtacaaaa aaatgttaaa ttttcacatt ttcatagtat actgtttaat agaaagtagg
    18961 ttctttgtaa ctgctccatt ataaaatcct ttcactcttc cggtatacta ttaggaaaaa
    19021 cataactgga ggatattttg agctcacacc tcatcgttcc agtggctgtt ccccaagctc
    19081 gtgtactgcc caaaaaagtt agacattcta tttagaacga ggattgagtt ctgtattgta
    19141 caaggctcgg tccttttaga gtcagcttaa ggctggcttt ttcaatcacc aaagtgtcag
    19201 aatgttttga caaatgaaca caaataatga tataatatgc aaaagctagg aggtggtagg
    19261 atgattgaaa aaatggaact gggggaattt tacaaggaat tgcgcttggc tagaaagctc
    19321 aagcagtcag atgtggcttg tgctggacta acagcctctc agttgtccaa gtttgaacta
    19381 ggacagtcta tgctgtctgc agacaagctg atcctagcca tccaagggat caatatgaat
    19441 tttgatgagt ttgggcacaa gctcaacaac tatcaagaat ctccacatat gcgaatcggt
    19501 cgaaaggttg tggatcgctt tgcccatcag gatatagctg ctttagagca gctattggag
    19561 gaagtcgatc aagaacagat ggcgcagacc tatcgtcgtt tgaatgccat tgtgattaaa
    19621 aatgcactcc attccttaga taaaagatac ccgctaacag aggaggatag cgagtttttg
    19681 actacctacc tctacgctat tgagtcttgg acctggtttg aactctatct tttttgcaat
    19741 actatgccct tcttgagcaa tcaagatctg atctttttat caacctcctt actcgaaaaa
    19801 tccaaggaat ttaaagagtt agtacacaat cgattgtata tgaagcaagg actcttaaat
    19861 atcttatcag aactcatgga gcgaaaactt ttcttataca tcccaatctt cgaagccgag
    19921 ttggagagca tgttgcgtcc gtacgatgtt tttgaaaaag tatcgtggca atttttaaag
    19981 aagatgagtg tctttcttca aacaaaggga agcaatcaaa aagagattga acgctttacc
    20041 caatctctgc aggtattaga aaatccacaa ttaacatccc tttttgaatt gcgttttcag
    20101 caatataaag aacttataga ttagttagaa atgggaaaaa gataataata tcagcaacga
    20161 tcgtcaataa tgttaaaact tgtttcttca tattacttcc ctcctcatta gtaataactt
    20221 tattatacca gggaaataat caaatctacc aaaatcgcaa atctgaaatt tctataagaa
    20281 aaaatatcaa atatgcgatt ttctaaaata agccaatttc cgtgttatac tgtccttgta
    20341 aaacatttga agcaaatcct aggtcgcaga agtggtttac aaatgaagat aattgaagga
    20401 gtgtaaaaga tgttaaattt acaatttgca gaaacaatgg aattgacaga agctgagttg
    20461 gagacagttt atggagggga acttgggtat aatgccgtta tcccaggtgg tagttgggga
    20521 ggtttaggaa cgtcttggtc aatcactaat ttctggaaga aaaattttaa cgatagacct
    20581 gactttgatt ctgaccgccg tcgttattaa tatccaaagc ccttgccttt tcttgggtag
    20641 gggctgtctt tatttcatat gtataggagg aaatagaatg aaaaagataa tctcacaccg
    20701 ctactttatt atagtttttc tactagttat tgctgaccag aagttcagtg ttttagtttt
    20761 acgcagcgac cttgttgctg ggctatctga ctttgcctat tatctgtcgg atatgatgtt
    20821 gaattttctt gtggttttat ttgctcttat tgctatgatt tggtcgggga aatggcagaa
    20881 aatcaatagt agaaagttta aaggatccta tcttttctat tccttcctag ctctgcttgc
    20941 ttttgttgct tggaattttg tcaccttttt tcttttccca cctactcgaa atgaaatttc
    21001 ttatcaacat gctgctccta cttttacagg agctacggca tttttgatgt atttttttta
    21061 tcctgtgatt gcaggtccca tttttgaaga catgatttat cgtggattag tgatgactgc
    21121 tctggaaaaa ggaaagaaat gggggctaga tgtacttggt tccgctgttt tatttggggt
    21181 ctcgcacatt agtaatcacg gttgggtctt gacagacttt gtcttctata tgggtggagg
    21241 tcttatattt gcagtcttat ttagaatgac aaagtcaatt tattggccta ttggactgca
    21301 tatagtctac aatggcattg gtcagctttt gatgttactg taattttggt tgttagtagt
    21361 atcgcggtct atccttgggg aaagattccc atttgaactt aagaaggagt tgtgatgaaa
    21421 gtatttcttc aaaatagaga ttttaggcaa ttaactatca accagtggat ttcaacgctt
    21481 ggggatacga ttttttatct ggccttcctg aattatgtgg cagatgcatc ttttgcccct
    21541 ttggcgattt tactcatcac gatttcagaa accctgcccc aagttctaca aatctttctg
    21601 ggagttttgg cggattttca acatcatcgt gtcttgaaat acacagtcat tagttttgca
    21661 aaatttttgc tttactctat agtgtcttta tcactttcag ggcagtcctt ttccttgtta
    21721 ttagtagcat ttatttgtct gattaacctc ttgtctgaca cgttgagtta tttttcaggc
    21781 gccatgctca ctccgatttt cattagaatt attgggcaag accatctggc agaagctatt
    21841 ggatttaaac agtcaactgt tagtttagtg aaaacaatca gtaatattct aggaggagtc
    21901 ttattaggta ttctatccat ccagtttatt tccttgctga acgctcttac ctttttaatc
    21961 gcatttttag gtatcctctt cataaaaact gacctcttga aagtagaaaa aacgattaac
    22021 tatcaagaag gactctctgt aaaatccttt tgccagcatt tgctccaatc atcgaaattg
    22081 atatggaata tgaataaggt gctcttggtt ttgtttatta tctctactag tcaagcagtg
    22141 ataaatgtta cagttcctgt ctctactcta tttttgagga atcaaccctt tttgaattta
    22201 caaacaggtc aatctcttgc cttgctatcc acttttgaac tgtcagccct gattgtcgga
    22261 agccttgtaa gtggctatct gaaacatacg atttctataa aaacagctct ctatgcctca
    22321 cttgtcaccc agttgcttct tctagtagga tttgccacag ttcgttttga ctggattctc
    22381 atctttagta ccttggatgc ctttttcgca ggtgttctct ctcctagatt gcaagaactc
    22441 gtttttaaac aaatacctga ggagtcaatg ggagcagttc aatcctctat cggtgccatt
    22501 acggttgttt tacctagctt atttacaata gctttggtaa ccattgctac tagctttgga
    22561 actctggcag ttagctttgt tttattgcta tttcttctag ttgcctttgt tatgcttctg
    22621 aatattcgtg aaagtattta gtggagaatt tctataatat atgtttgaga ctggattgcc
    22681 agtcttttta tgatggtcaa aatcaacaga ctttttctct tttctgaatg tgttatagta
    22741 aactgaatct aaaatagtat gaaacaattg ctaaaacatt tatagaaatt aattttactt
    22801 tcccaatcga tttgttctca tcttatttca atctgctata taatagtcca tgctgtgact
    22861 ggattctttt cagcctactt atactcttcg aaactctctt caaacca
//
LOCUS       DAVAGB010000034        22246 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVAGB010000034 DAVAGB010000000
VERSION     DAVAGB010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22246
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.034"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            94..557
                     /locus_tag="VQO19_001466"
                     /pseudo
     CDS             94..557
                     /locus_tag="VQO19_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883906.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
     gene            714..1139
                     /gene="lacA"
                     /locus_tag="VQO19_001467"
     CDS             714..1139
                     /gene="lacA"
                     /locus_tag="VQO19_001467"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HET1349706.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1170..1685
                     /gene="lacB"
                     /locus_tag="VQO19_001468"
     CDS             1170..1685
                     /gene="lacB"
                     /locus_tag="VQO19_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HET1349707.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTAFYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1696..2625
                     /locus_tag="VQO19_001469"
     CDS             1696..2625
                     /locus_tag="VQO19_001469"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HET1349708.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYCASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFTKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2627..3607
                     /gene="lacD"
                     /locus_tag="VQO19_001470"
     CDS             2627..3607
                     /gene="lacD"
                     /locus_tag="VQO19_001470"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HET1349709.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQRTATSWKERV"
     gene            3909..5309
                     /gene="lacG"
                     /locus_tag="VQO19_001471"
     CDS             3909..5309
                     /gene="lacG"
                     /locus_tag="VQO19_001471"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET1349710.1"
                     /translation="MRTLPKDFIMGGATAAYQAEGATQIDGKGPVAWDSFLIEKGRYT
                     AEPASDFYHQYPVDIELCKKFNIDSIRLSIAWSRIFPDGFGEVNQLGVDFYHSVFSEC
                     ISNGIIPFVTIHHFDTPKNLFEKGDFLNRENIEHFVNFAKFCFEEFKEIEYWSTFNEI
                     YPLATNQYLTGVFPPEIKFDFEKVITCLHNMMYAHARVVNIFKEGNYRGKIGVVHSLE
                     PKYPYSDKPEDIHAAKVDEALSVRFLLDATYLGEYSSSTWNLVQEILYKNNMSVSIDS
                     NDFIEMRKASERNDFLGINNYVSHWVKAYEEESTLFYNTTGEKGTQVYRIKGVGERVP
                     REDLPKTDWDWIIYPEGLYDLLTFIKEEYPNYKEIYITENGLGFKDEFTDGIILDEPR
                     IDYLRGNFESISRAIDDGVNVKGYFIWSLMDVFSWVNGYDKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSQTKTII"
     gene            5323..6978
                     /locus_tag="VQO19_001472"
     CDS             5323..6978
                     /locus_tag="VQO19_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HET1349711.1"
                     /translation="MNGIIKQIEKHQELFQRISANIYLTAIKDGFLTAMPVILFSSLF
                     ILCAAIPPLVGIKLPESFETWLWKIYDYSMGIVGLLVAGTTARCLAGSMNRKMPSGKV
                     INEVSVMLASIVSFLLLAVTKMDGAFQGDFFGTKGILSSFVAAFITVNVYKFCVIKDI
                     TIKMPKEVPGSISQNFRDVFPFSFSVFFAAIIDIATRYYLNVPFAEVFSKILSPVFQG
                     AETYLGLSIIWFLVPFFWFVGVHGPSVVKPGLAAALYGNTEANLELFRNGQHPFHALT
                     ENFGNFVGELGGTGATFIVPIIFILFMKSKQLKAVGKASIVPVMFAVNEPLLFAAPIV
                     LNPYFLIPFCLAPIVNVILGKFFISVLGMNGYMHVLPWATPGPIGNLMSTHFQPISFV
                     FTVLLLVVDFIIYYPFCKAYDKVLLSEETKNANTEDRFETNNSTKVDESETVQLEKEI
                     KILVLCAGAGTSAMLANALTEGASSLNLPLSSSAGAYGSHYEIMKYYDMVILAPQVKT
                     YYNDIKKDTEKLGIKLIATEGAEYINLTRNPEKAVQFVLEKLN"
     gene            7200..8033
                     /locus_tag="VQO19_001473"
     CDS             7200..8033
                     /locus_tag="VQO19_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET1349712.1"
                     /translation="MFRIVNVINNNVALAKNENHEEVMITGNGIAFQKKKGDIIVQSK
                     IEKVFRLNTEESKNNFLTLLQDVPLDFITVTYDVINSLISKYHYPFQEYLYVTLTDHI
                     YSAYQAIHKGIYEDGKLPDISVDYPLEFEMAEYALDMFKKKLLDSFPDNETERIALHF
                     INAKGGDNQGINLQIDQSKQIIEHIKRELANHNIVRRKENAPLFDRFMIHLNYFLEYL
                     DRSRSDNPSLLDMEGYIETVYPLAYEIGDKIYWIIASETGVALHRSERVYIVLHIQRL
                     L"
     gene            8060..8377
                     /locus_tag="VQO19_001474"
     CDS             8060..8377
                     /locus_tag="VQO19_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET1349713.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            8377..10068
                     /locus_tag="VQO19_001475"
     CDS             8377..10068
                     /locus_tag="VQO19_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET1349714.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIENGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VEAAQNTITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            10283..11689
                     /gene="lacG"
                     /locus_tag="VQO19_001476"
     CDS             10283..11689
                     /gene="lacG"
                     /locus_tag="VQO19_001476"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET1349715.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVSRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVNNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            11732..11989
                     /locus_tag="VQO19_001477"
     CDS             11732..11989
                     /locus_tag="VQO19_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HET1349716.1"
                     /translation="MFKDFIQSIYEKVYIINFEKYSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDDDLEEFKNLFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(12268..13029)
                     /locus_tag="VQO19_001478"
     CDS             complement(12268..13029)
                     /locus_tag="VQO19_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET1349717.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(13211..14173)
                     /gene="nrdF"
                     /locus_tag="VQO19_001479"
     CDS             complement(13211..14173)
                     /gene="nrdF"
                     /locus_tag="VQO19_001479"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HET1349718.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(14361..16520)
                     /gene="nrdE"
                     /locus_tag="VQO19_001480"
     CDS             complement(14361..16520)
                     /gene="nrdE"
                     /locus_tag="VQO19_001480"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HET1349719.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(16602..16820)
                     /gene="nrdH"
                     /locus_tag="VQO19_001481"
     CDS             complement(16602..16820)
                     /gene="nrdH"
                     /locus_tag="VQO19_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HET1349720.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            17171..17434
                     /locus_tag="VQO19_001482"
     CDS             17171..17434
                     /locus_tag="VQO19_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HET1349721.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            17440..19173
                     /gene="ptsP"
                     /locus_tag="VQO19_001483"
     CDS             17440..19173
                     /gene="ptsP"
                     /locus_tag="VQO19_001483"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HET1349722.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFEAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            19427..21877
                     /gene="phtA"
                     /locus_tag="VQO19_001484"
     CDS             19427..21877
                     /gene="phtA"
                     /locus_tag="VQO19_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET1349723.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHF
                     IPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSN
                     SSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKE
                     NVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDL
                     LAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYV
                     TPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVK
                     GEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLF
                     ATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVP
                     QVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKL
                     LALLKGSNPSSVSKEKIN"
     gene            22035..>22246
                     /locus_tag="VQO19_001485"
     CDS             22035..>22246
                     /locus_tag="VQO19_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET1349724.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIV"
BASE COUNT         7153 a         3829 c         4517 g         6747 t
ORIGIN      
        1 attaatttga ttgctggcat tatcaatcat gaactaggat tctagttttg caggaagtct
       61 aataaagaaa ctagcaaggt caggccttac tttattggtg gacatccagg atttaattgt
      121 cctctacttg atgatgaagt ctatgaagat tattatctag agtttgagaa agaagagatt
      181 tgctctgttc cacgtccttt cccagaaaca ggtatgttgg atttccaaga tagaagtcca
      241 tggctagagg gacaaaaaga aatagatctt agttatgatc ttttcagcac agatgcagtg
      301 actttggatg aattgcaatc tcgaacaatt gcccttcgtt ctcttaaaca tgataaggga
      361 ttgaaagtgc attttgcaga atttccaaac ctcatcatct ggtcaacttt gaacaaggga
      421 cctttcatta cctttgaacc atggtctggc ttgtcaacat tcttgaagaa ggagatcatt
      481 tagaagataa gaagaatgtt tgtctcttag aagccaatca ggttgaagaa ttagggtttg
      541 agatagaagt tttataaaaa agtaaaaaat aaataacaaa aacaaacaca aactattgac
      601 ttcttcaaac aatagtagta tattatgttt gtgaggacta attgactgtt ttttaaagat
      661 agccaataca ctgctggaat ccagcataga aaaaataaaa aggagtatac aatatgtcta
      721 ttgttatcgg tgcagatgct gcaggtttga gattgaaaga agttgtgaaa gacttcttag
      781 aaaaagaaaa cttccacctt gtggatgtta cagctgaagg tcaagacttt gttgatgtga
      841 ctctcgctgt tgctgcagaa gtaaacaaag aagaacaaaa ccttggtatc gtgattgatg
      901 cttatggagc tggtccattt atggttgcaa ctaagatcaa aggaatggtt gctgcagaag
      961 tatctgacga acgttcagct tatatgactc gtggccacaa caactcacgt atgatcacta
     1021 tgggggcaca acttgttggt gatgaattgg ctaaaaacat cgctaaagga tttgttaatg
     1081 gtaaatacga cggtggtcgt caccaaatcc gggttgacat gttgaacaaa atgggctaat
     1141 tagattacag taagaaaggt aagttaaaaa tgagaattgc aattggatgt gaccacatcg
     1201 taacagatga aaaaatggcg gtttcagaat ttttgaaatc aaaaggatat gaagtcattg
     1261 actttggtac ctatgaccat acacgtactc actacccaat ctttggtaaa aaagtagggg
     1321 aagcagtaac tagtggtcaa gctgatctcg gggtatgtat ctgtggtact ggtgttggta
     1381 tcaacaacgc tgtaaataaa gttccaggtg ttcgttctgc cttggttcgt gatatgacaa
     1441 cagcctttta tgctaaagaa caattgaacg ccaacgttat cggttttggt ggtaagatta
     1501 ctggtgaatt gcttatgtgt gatatcatcg aagctttcat tcatgctgaa tacaaaccat
     1561 ctgaagaaaa caaaaaattg attgcgaaaa ttgaacacct tgaaagtcac aatgctcaac
     1621 aaacagacgc aaacttcttc actgaattcc ttgaaaaatg ggatcgtgga gaataccacg
     1681 actaagaggt aacctatgat tttaacagtt acaatgaacc catccattga tatttcctat
     1741 cccttggatg agttgaagat tgatactgtc aatcgtgtgg tggatgtaac caaaacggct
     1801 ggtggtaagg gactcaatgt tacccgagta ctttcagaat ttggcgattc tgttcttgct
     1861 actggtttag tgggtggcaa acttggtgag tttttggttg aacatatcga taatcaagta
     1921 aagaaagatt tcttctcaat tcagggagaa actcgtaact gtatcgctat tctccacgga
     1981 gacaaccaaa cagaagttct tgaaaaaggt cctgaagtat tggaacagga aggtcaagac
     2041 tttttggaac atttcaaaaa actcttggag tcagttgaag tagtggccat ctcaggtagt
     2101 ctgccagctg gccttccagt tgattactgt gcgagcttgg tagaacttgc taatcaagct
     2161 ggcaagcctg tagtcttgga ctgctcaggt gcagcacttc aggctgttct tgaatcaccc
     2221 cataaaccaa cagtcatcaa accaaataat gaagaattgt ctcagcttct tggaagagaa
     2281 gtttctgagg atttggatga attaaaagaa gtacttcaag aacctttgtt tgcagggatt
     2341 gaatggatta tcgtttcact tggtgccaac ggtactttta ccaaacatgg tgacactttc
     2401 tacaaggtag atattcctag aattcaggtg gtaaatcctg ttggatctgg agactctact
     2461 gtggcaggaa tttcttcagg acttcttcac aaagaatcgg atgcagaatt actcatcaag
     2521 gcaaatgtcc ttggtatgct caatgctcaa gaaaaaatga ctggtcatgt caacatggcc
     2581 aactatcaag ctctatatga tcaattaata gtaaaagagg tataaaatgg ctttaacaga
     2641 acaaaaacgt gtacgcttag aaaaactttc tgatgaaaat ggtatcatct cagctcttgc
     2701 atttgaccaa cgtggtgctt tgaaacgcct catggctcaa caccaaacag aagaaccaac
     2761 tgtggcccaa atggaagaac ttaaagtttt ggtagcagat gaattgacta aatacgcttc
     2821 atctatgctt cttgaccctg agtatggact tccagcaact aaagctcttg atgaaaaagc
     2881 tggtcttctc cttgcttatg aaaaaacagg ttatgacaca acaagcacaa aacgcttgcc
     2941 agactgcttg gatgtttggt ctgcaaaacg tattaaagaa gaaggtgcag atgcagttaa
     3001 attcttgctt tactatgatg tagatagctc agacgaactc aatcaagaaa aacaagccta
     3061 catcgaacgc atcggttctg agtgtgtggc tgaagatatc ccattcttcc ttgaaatcct
     3121 tgcttacgat gaaaaaattg cagacgcagg ttctgtagaa tacgctaaag taaaaccaca
     3181 caaagttatc ggcgctatga aagtcttttc agacccacgc tttaacattg atgttttgaa
     3241 agttgaagtt cctgttaaca ttaaatatgt tgaaggcttc gctgaaggtg aagtagttta
     3301 tacacgtgaa gaagcagcag ccttcttcaa agcgcaagat gaagcaacga acttgccata
     3361 catctacttg agtgctggtg tatcagctaa actcttccaa gatactcttg tatttgctca
     3421 tgaatcaggt gcaaacttta acggagttct ttgtggccgt gctacatggg caggatcagt
     3481 tgaagcttac atcaaagatg gtgaagcagc agctcgcgaa tggcttcgca caactggatt
     3541 tgaaaacatt gacgaactca acaaagttct tcaaagaaca gcaacttcat ggaaagaacg
     3601 cgtgtaagaa ctattaattt caatagttca aaatttagtt attaagtttc tataaaagtg
     3661 atacttcata tctgaaaaga taatggacta tcgctttttt tcttctcaaa attttcaatt
     3721 ttctattgac aaacagaata aatagcgata caatatagtt ataataaata aactaataat
     3781 agtggatcgt aacttaaagg cgaaaccgca aataatctta gcttttgcta gactatttgc
     3841 ggttttttgt ttagaaagga ggaaaaacaa gatctacaat gttattagaa aaaagaaaag
     3901 gagaacaaat gaggacatta ccaaaagatt ttatcatggg tggagctact gctgcatatc
     3961 aagctgaagg tgcaactcaa attgatggga agggaccagt agcatgggat agttttttaa
     4021 ttgaaaaagg acgctataca gcagaaccag ctagtgattt ttatcatcaa tatccggttg
     4081 atattgaatt atgtaaaaaa tttaacatag atagtattag actatctatt gcatggagta
     4141 gaatttttcc agatggtttt ggagaagtaa atcagcttgg agtagatttt tatcattccg
     4201 ttttctcgga atgtataagt aatggtatta taccatttgt aacgattcat cattttgata
     4261 caccaaaaaa tttatttgaa aaaggagatt ttctaaatag ggagaatatt gaacatttcg
     4321 taaattttgc taaattctgc tttgaagaat ttaaagaaat tgaatattgg agcactttca
     4381 atgagattta tccacttgca actaatcaat atttgacggg agttttccct ccagaaataa
     4441 aatttgattt tgaaaaggta attacgtgtc ttcacaacat gatgtatgct catgcaaggg
     4501 tagttaatat ttttaaagaa ggtaattata gaggtaaaat aggcgttgta cattctctgg
     4561 aaccaaagta tccatatagt gataaaccag aagatattca tgctgcaaag gttgatgaag
     4621 ctttatcagt ccgttttcta ttagatgcaa catatttagg ggagtatagt tcttcaactt
     4681 ggaatcttgt tcaggaaata ctctataaaa ataatatgtc tgtttcaatt gatagcaatg
     4741 attttataga gatgagaaaa gcttcagaaa gaaatgattt cttaggtatt aataactatg
     4801 ttagtcattg ggtaaaagcc tacgaggaag agagtacttt attttataat acgacaggtg
     4861 aaaaaggaac tcaagtttat cggattaaag gagttggaga aagagtacca agagaagacc
     4921 ttcctaagac agattgggat tggattattt atccggaagg tttatatgat ttgttgacgt
     4981 ttataaaaga agagtatcca aactataagg aaatctatat tactgagaat ggtcttggtt
     5041 ttaaagatga attcactgat ggaattatat tagatgaacc tagaattgac taccttcgag
     5101 gaaacttcga atcaatttca agagcaattg acgatggtgt caatgttaaa ggatatttca
     5161 tttggtcttt aatggatgta ttttcttggg ttaacggcta tgataaaaga tatgggttgt
     5221 tctacgtcga ctttgaaact cagaaacgat accctaaaga atcagcttat tggtataagt
     5281 tagttagtca aactaaaact ataatttaga ggaggaaata aaatgaatgg aattattaaa
     5341 caaattgaaa aacatcaaga attatttcag cgtatttctg caaatatata cttgactgct
     5401 ataaaagatg gttttctaac agctatgcca gtaatattat tttctagcct tttcatctta
     5461 tgtgcagcaa tacctccttt agttggtatc aagttgccag aaagttttga gacatggtta
     5521 tggaaaatat atgattattc aatggggata gtaggcttat tagtagctgg tacaacagct
     5581 agatgtttag ctggaagtat gaatagaaaa atgccttctg gaaaagttat aaatgaagta
     5641 tcagttatgc tagcttctat cgtcagtttt ctattattag ctgtgactaa aatggatgga
     5701 gcatttcaag gggatttctt tggaactaaa ggtattcttt catcatttgt agcagcgttt
     5761 ataacagtaa atgtttataa attttgtgta ataaaagata ttacaattaa aatgcctaag
     5821 gaagttcctg gtagtatctc acagaatttt cgagatgttt tcccgttttc tttttcagta
     5881 ttttttgcag cgataataga tattgcaacc agatattact tgaatgtgcc atttgcagaa
     5941 gttttttcaa aaattttatc gcctgttttt caaggtgctg aaacttatct tggattatca
     6001 attatctggt ttttagtacc attcttttgg tttgttggtg ttcatggtcc atccgtagtt
     6061 aaaccaggat tagctgcagc gttatatggt aatacagaag ccaatttaga attatttaga
     6121 aatggacaac atccgtttca tgctctgacc gaaaattttg gtaatttcgt gggagaattg
     6181 ggaggtacag gtgcaacttt tatcgttcca attatattta ttctttttat gaaatctaaa
     6241 cagttaaaag ctgtaggaaa ggcatcaatt gtaccagtaa tgtttgcagt aaatgaacct
     6301 cttctgtttg ctgcaccaat tgttctaaat ccatattttc tgattccatt ctgtttagca
     6361 ccaattgtaa atgtaatttt aggtaagttt tttattagtg tattaggaat gaatggatat
     6421 atgcatgtat taccatgggc tacgccaggg ccgattggaa atctaatgag cacacatttt
     6481 caacctatta gctttgtctt cacagtgtta ttattagttg ttgattttat aatttattat
     6541 ccattttgta aagcgtatga taaagtgtta cttagtgaag aaacaaaaaa tgctaataca
     6601 gaagatagat ttgaaactaa caattctact aaagtagatg aaagtgaaac tgtgcaactt
     6661 gaaaaagaga ttaaaatctt agtattgtgt gctggtgctg gaactagtgc aatgttagct
     6721 aatgcactta cggaaggtgc aagcagttta aatttaccat taagctcatc agccggtgct
     6781 tatggctcac attatgaaat tatgaaatac tacgacatgg taattttggc accacaagta
     6841 aaaacctatt ataatgatat caagaaagac acagaaaaac tgggtattaa attaattgcg
     6901 acagagggag cagaatacat aaatcttaca agaaatccag aaaaggctgt tcaattcgta
     6961 ttggaaaaac taaactaaaa aatgtttgaa atgaacaaaa aaaaacgaag taagggttta
     7021 caatggttct tatttttgat ataatactat caaagattga atagagtgga tcgttactga
     7081 gtaatattag gcgagactgc aaatgaggaa agtaactttc actctggtga gttatgccca
     7141 tttgtggtct cttttatttc atttagttca atttaaattt tataggaaag gagaagtgga
     7201 tgtttcgtat tgttaatgtt atcaataata atgttgcttt agcgaaaaat gaaaatcatg
     7261 aggaagtaat gataacagga aatggtatcg cttttcagaa gaaaaagggt gatatcattg
     7321 ttcaaagtaa aattgaaaag gtttttagat tgaatacaga agaatctaag aataattttc
     7381 taactttatt acaggatgtc cctcttgatt ttattacggt aacttatgat gttattaatt
     7441 ctctaatatc taaatatcat tatccttttc aagagtatct atatgtaact ttaacagatc
     7501 atatttacag tgcttatcaa gctattcata agggaattta cgaagatggt aaacttccag
     7561 atatttctgt tgattaccca ctagaatttg aaatggctga atatgcactt gatatgttta
     7621 agaaaaagtt gttggatagc tttccagata atgagacgga aagaattgcg ttacatttta
     7681 tcaatgcaaa aggtggagac aatcaaggta taaatttaca gattgatcaa tcaaagcaaa
     7741 ttattgagca tatcaagcgc gaacttgcaa accataatat tgtaagaaga aaggaaaatg
     7801 ctcctttatt tgatcgcttt atgattcatc taaattactt tctagaatac cttgaccgat
     7861 ctagaagtga caatccttcc ctgttggata tggaaggata tattgagaca gtttatccct
     7921 tggcctatga aataggcgat aaaatttatt ggataattgc tagtgagact ggggttgctc
     7981 ttcatcgaag tgaaagagtt tatatagtct tacatattca aagattactt taaaaaattt
     8041 ttataaggag aattctatca tgaatagaga agaagtaaca ttgttaggtt ttgaaatcgt
     8101 agcctatgct ggcgatgctc gttcaaaact attggaagcc ttgaaggctg ctgaagctgg
     8161 tgattttgaa aaagcggacg ctctggtaga ggaagctggt agctgtattg cagaggctca
     8221 ccacgcgcaa acaagtctat tgactaagga agcttcaggt gaggacttgg cttatagtgt
     8281 aaccatgatg catggccaag accacttaat gacaactatc ttgttaaaag atttgatgca
     8341 tcatttaatt gaactctaca agagaggagt taaataatga ataaactaat tgcatttatc
     8401 gagaaaggaa agcctttctt tgaaaaacta tctcgtaata tctatcttcg tgctattcgt
     8461 gatggtttca ttgcaggtat gcctgttatt ctcttctcaa gtatctttat cttgattgcc
     8521 tttgtaccaa actcatgggg ctttaaatgg tctgatgaag ttgtagcctt tctgatgaaa
     8581 ccttatagct attctatggg tattctggct ctcttggtag ctggtacaac agctaagtca
     8641 ttgaccgact cagtaaaccg gagcatggag aaaaccaatc aaatcaacta tatgtcaacg
     8701 ctgttagcag cgattgttgg tttgttgatg ttggcagctg atcctatcga aaatggtcta
     8761 gctactggat tcttggggac aaaaggtttg ctttcagcct tccttgctgc ctttgttact
     8821 gtagccatct ataaggtttg tgttaagaac aacgtcacta ttcgtatgcc tgacgaagtt
     8881 ccaccaaata tctcacaagt ctttaaagat gtgattccat tcactctatc tgttgtttct
     8941 ctttatgctc ttgacttatt agcacgtcat tttgttggct ctagtgtggc agaatcaatc
     9001 ggtaaattct tcgcaccact cttctcagca gcagacggat accttggtat taccattatc
     9061 tttggtgcct ttgccttctt ctggtttgtt gggattcatg gtccatctat cgttgaacct
     9121 gctatcgcag cgattaccta tgcaaatgct gaagtcaact tgaaccttct ccaacaaggt
     9181 atgcacgctg acaagattct tacttctggt acacaaatgt ttatcgttac catgggtggt
     9241 actggtgcga cactggttgt tccattcatg tttatgtggt taacaaaatc aaaacgtaac
     9301 cgtgcaatcg gacgtgcttc agtagttcct accttcttcg gtgtaaatga accaatcttg
     9361 tttggtgcac cacttgtatt aaatccaatc ttcttcattc catttatttt tgctcctatc
     9421 gcaaacgtat ggattttcaa attctttatt gaaacacttg gaatgaattc atttactgct
     9481 aatctaccat ggacaacccc agctccacta ggtctagttc ttggtactaa cttccaagtt
     9541 ctatcattca ttcttgctgc ccttctaatc gtggttgacg ttgtcattta ctatccattc
     9601 cttaaggtct atgatgaaca aattcttgaa gaagaacgtt caggtaagtc taatgatgaa
     9661 ttgaaagaaa aagttgctgc aaacttcaac actgcaaaag cggatgctat tcttgaaaaa
     9721 gcaggtgtag aagcagcaca aaatacaatc actaaagaaa caaatgtcct cgttctttgt
     9781 gcaggtggag gaacaagtgg tctccttgca aatgctctaa acaaggcagc agcagaatac
     9841 aatgtccctg tgaaagcagc agcaggtggc tatggtgctc accgtgaaat gttgccagag
     9901 tttgatttgg ttatccttgc tcctcaagtt gcttcaaact ttgaagatat gaaggcagaa
     9961 acagataagc tcggtattaa acttgctaag acagaaggcg ctcaatacat caaattaact
    10021 cgtgatggaa aaggtgccct agcattcgta caagagcaat tcgattaagg ctaggaactg
    10081 tgaaacagtc tcccatcgtt acggaaatcg ctatggcgaa tttcctaatc gccttattaa
    10141 ttcgtcggta aaaagatatc gtttttacct cctcatgtca caattcggtg acttggtaca
    10201 agaagtgaga tggagaagga tggctcactg actcctctcc tctcactttt actttattta
    10261 aatcaagaaa taggtgaaaa aaatgacaaa aacacttcca aaagacttta tttttggtgg
    10321 cgcaacagct gcctatcaag cagaaggtgc tacacatact gatggtaaag gaccagtagc
    10381 gtgggataaa tatcttgaag ataactactg gtacactgca gaaccagcca gtgattttta
    10441 caatcgatat ccagttgacc tcaagctagc agaagagtat ggtgtcaatg gtattcgaat
    10501 ttctattgct tggtcacgta ttttcccgac tggttacggc caagtaaatg ctaaaggtgt
    10561 tgagttttat cataatttat ttgcagagtg tcacaaacgt catgttgagc cttttgtaac
    10621 tcttcatcac tttgacacgc cagaagctct ccactcaaat ggagacttct taaaccgtga
    10681 aaatatcgaa cattttgtag actacgctgc cttctgtttt gaagaatttc cagaagtaaa
    10741 ctattggaca acctttaatg aaattggacc aatcggtgat ggtcaatatt tggttgggaa
    10801 attccctcca ggtatccagt acgaccttgc caaagtcttt caatcacacc acaatatgat
    10861 ggtgtctcat gcacgcgcgg taaaattgta caaagagaaa ggctataaag gggaaattgg
    10921 tgttgttcac gccctgccta ctaaatatcc tctagatcct gaaaatccag cagatgttcg
    10981 tgcagcagag ttggaagata tcatccacaa taaattcatc ttagacgcaa cttatctagg
    11041 tcgctattca gctgaaacca tggaaggtgt caaccatatc ttatcagtca atggtggtag
    11101 tttggatctt cgtgaagaag attttacagc attagaagct gcaaaagact tgaatgattt
    11161 cctaggaatc aactactata tgagtgactg gatggaagcc tttgatggag aaactgaaat
    11221 tatccataat ggtaaaggtg aaaaaggaag ctctaagtat caaatcaaag gtattggtcg
    11281 tcgtgtagct cctgactatg tatcacgcac ggattgggat tggattatct accctcaagg
    11341 tttgtatgac caaatcatgc gtgtgaagaa agattatcct aactacaaga aaatttatat
    11401 cactgaaaat ggtctcggct ataaagatga gttcgttaat aacactgttt acgatgatgg
    11461 tcgtattgat tacgtgaaac aacacttgga gatcttgtct gatgcgattg cagatggagc
    11521 taatgtaaaa ggttacttca tttggtcatt aatggatgtc ttctcatggt caaacggtta
    11581 tgagaaacgt tatggtctct tctacgtaga ttttgaaact caagaacgtt atcctaagaa
    11641 atcagctcac tggtacaaga aagtagcgga aactcagatt atagactagt agaattagtc
    11701 attagatata gaattttagt gagtcaaaaa gatgttcaaa gattttatcc aatctattta
    11761 tgaaaaagtt tatattataa atttcgaaaa atactctcaa ataccgtgtt tgacgagtga
    11821 agaattgaaa agtcttggaa aatggtatgt ctcgactggt aaagaatgga tttgtcattc
    11881 agatgatgat ctggaagaat ttaaaaatct atttttaaat tttatcaatc ctgaagaatg
    11941 ggatactatc tcctttgatt cagattttat gccgtttcaa caatcgtaac caatttctca
    12001 aaaaagttaa atcttatatt tagtactctg taaaactctt atctaatcac gttgcttata
    12061 ctcaatgaaa atcaaagagc aactttaaac taggaagcga gtcgcagatt tctcaatgta
    12121 tagctttgag gaattgggca aaaagtcttt gatatagaaa aaagcatagt atcaggtgtt
    12181 tcaacacctg atactatgct ttttattgtg ggaagattta ctttttttct tctgaaattg
    12241 agttgttacc caggctcttt cagtttatta aggcttgatg actttaatgt gtttagatag
    12301 cttaaaaagg attgaatcac ttagtttaga atctgaaaca atagtatcaa gatttgatat
    12361 attataaaaa gtataaaaat caaacttatt gaacttacta tgatctgcga gtaaatattt
    12421 tttattagaa ttatttaaag cgatgcgttg agcctctccc tcttcctcgc taaaagtagc
    12481 tagagctccg ttttgaatac cattacagct aacgaaagct ttagaaaatt ggagattaga
    12541 gagattttgt agggtcaatg tgccaacaaa agcacctgta atatcgcgat aatttccacc
    12601 tatcaaaatc aaatctgtta attttcgttc gcttaaaatc agaaaaacag gtagactgtt
    12661 ggttacgacg cggatattgt caataggcaa ctcacgcgca aaaaactcta atgttgttcc
    12721 tggtccaatg aaaatagttt ctctttcttc tactagactg cctgcaaaat gggctatttc
    12781 ttgtttttct gccgtttgga gggcttgttt ttcaatattt gatcgctcat tagtcaaaag
    12841 ggagttggtt cgaagttttt cagctccacc atgcacacga atcagcaaat ctttatcagc
    12901 taattcctgt aaatagcgcc ttgcagtcat atctgaaacg gctatttcgt ccataatctg
    12961 tttaactgtt atggttcctt tactatttac tatctctaaa attttggtta atttttcttg
    13021 tttgagcata ttatcacctc gtttcctact actatcttac cataaacaaa ctcatcattc
    13081 aaatacaaaa acaacaaaat gaaacaaaaa caaaaatatc gaagtttgtt ttcaaaactt
    13141 tcgatatttt tgttgggtta taactttgat gtttctagtt tactttttga tgattgagag
    13201 tgatggagaa ttagtctaaa ccgtagttat agtcatcgtc ttgcatggct tcaacttcgc
    13261 caagaaggta accatttccg acttgagaga agaagtcatg gttggaagtt cctgttgaaa
    13321 taccgttcat aacgattggg ttgacatctt cagctgaatc tgggaaaagt ggatcttgtc
    13381 ccatgttcat gagagcttta ttggcattgt agcgaaggaa ggttttaacc tcttcagtcc
    13441 aaccaacacc gtcataaaga ctctctgtgt agccttcttc attttcataa agagtataga
    13501 gtaggtcgta catccattct ttgagttttt cttgctcttc ttcaggcaat tcattgaaac
    13561 caagttggaa tttgtaacca atgtaggttc cgtgaacaga ctcgtcacga ataatcaatt
    13621 taatgatttc tgcaacgttg gctagtttgt tgttaccgag atagtagagg ggagtgaaga
    13681 aaccagagta gaagaggaag gtttcgagga agacgctggc aactttcttt tcaagtgggc
    13741 tgccgtttag gtagatttcg ttgacaatct cagccttctt ttgtaggtaa ggattggtat
    13801 tggtccattc gaaaatttct tcaatctcag ccttagtatt caaggtagaa aagattgatg
    13861 agtaagattt agcgtggaca gattccataa attggatgtt attgaaaaca gcttcctcat
    13921 gtggtgtacg gatgtctgcg cgaagggctt gaaccccagt ttcagattgc atagtgtcaa
    13981 gaagggttaa accaccaaaa acttttccga ccaagtcttt ctctttgtta gatagctttc
    14041 tccagtcatc caagtcgttt gataagggaa tacgtgtatc gagccaaaat tgctccgtca
    14101 gtttttccca agttgatttg tcgatgacat cttcgatggc attccagtta atggctttgt
    14161 agtaagtttc catttaaaat ctctttctgt gtttagtatt gcgaactcac aattatttct
    14221 actttaccat aattctatag gagtatcgca caaaaagtcg gaagcccgac ttttaaaatg
    14281 ttacataaat tatgttatga catagtagat ttgattttat ctgtgctgct tagggaaaaa
    14341 taatgtttct atgctagaaa ctaaatcaca cagctttcac attggttggc gccgacttct
    14401 ccaccgtcat ctgtaaaggt acggacgtag tagatagact tgattccctt gttaaaggca
    14461 tagttacgaa ggatggacaa gtcacgtgtc gtttgtttat tttccctctt ccattcgtaa
    14521 aggccttttg gaatgtcact acgcatgaag agggtgagtg aaagtccttg atccacgtgt
    14581 tcagtcgcag cagcgtaaac atcgatgact ttacgcatat ccatatcgta ggcagaagtg
    14641 tagtaaggaa tggtttctgt agacaagcca gcagcagggt agtagatttt accaattttc
    14701 ttctcttggc gttcttcgat acgttgcgta atcgggtgga tagaagcaga aacgtcgttg
    14761 atatagctga tagaaccatt tggcgctaca gcaaggcgat tttggtggta aagaccatct
    14821 tcttgaacct tgtcgcgaag ttcagcccaa tcagcaacac cagggataaa gacatttttg
    14881 aagagttctt taacacggtc tgatgttgga acaaattcac cagttacata cttgtcaaag
    14941 taacttccgt tagcatagtc tgatttttca aagttgtgga aggtaatacc acgttcacgc
    15001 gcaatattgt ttgactctac caaggtccag tagttcataa gcataaagta gatgcttgta
    15061 aattcaacag actcaggtga accatattca atgagttgtt gggcaaggta gctgtgcagt
    15121 cccatggcac cgagaccaaa ggtgtgggct tggctatttc catggtcaat cgttggtaca
    15181 gctacgatat gtgaactatc tgtaacgaaa gtaagggcac gaaccatagc acggatagaa
    15241 cgaccaaaat caggtgaagt catcatgtta accacgttgg ttgaacccag gttacatgaa
    15301 acatctgttc ccatttgaag gaattcttga gcatcgttga tcaagcttgg ttcttgaact
    15361 tgaagaatct cagaacacaa gttactcatg ataatctttc catcaacagg atttgcacgg
    15421 ttagccgtat ctatgttgac tacataagga tagccagact cttgttgcaa tttagagatt
    15481 tcagtttcca aatcccgcgc cttgattttt gtcttgcgaa tatttggatt tgcgaccaat
    15541 tcatcgtatt tttcagtaat gtcgatgtaa ttgaatggca caccgtattc tttttctaca
    15601 gagtaagggc tgaagaggta catttcttca tttttacgag ccaattcgta gaatttatca
    15661 ggtactacaa caccaagtga tagagtcttg acacgtactt tttcatcagc gttttctttc
    15721 ttagttgaaa ggaaagcgat gatatctggg tgaaagacgt tgaggtagac aacaccggca
    15781 ccttgacgtt gccccaattg gttggagtaa gagaagctgt cttcaaaaag cttcataaca
    15841 ggaacgacac ctgaagcagc tccttcatag cctttgatag gtgcaccagc ttcacgaagg
    15901 ttgctgaggg taattcccac accaccacca atacgtgaaa gttgaagagc tgagttgata
    15961 gaacgtccga tagagttcat atcatccgtc acttggatta ggaaacaaga taccaactcc
    16021 ccacgacgag cacgtccagc attcaagaag gaaggagtag caggttggta gcgttggtgg
    16081 atgatttcat tggcaatatc gattgcaaca gcttcattcc catcagcgaa ataaagggcg
    16141 ttgaagaaga cacggtcttc catattttca agatagtatt caccgtcatt agtctttaag
    16201 gcatattgat tgtaaaattt ataagctgcc atgaatgact tgaattggaa gttttggtct
    16261 ttgataaatt gagccaattc ttccaagaac tctggacggt atttcttgat aaaggctgtt
    16321 tcgatgtagt tgtgttcaat gaggtaattg attttgtctt tgattgaatc aaaaaccata
    16381 gtgtttggaa ctacattttc tttaaagaaa gcatccaagg cttccttatc tttatgaagc
    16441 atgatttgtc cattaacagg acggttaatt tcgttattaa gacggaagta agtcacgtct
    16501 tcaagatgtt ttaatcccat aaaatttccc ttatctaatt acaaaagaaa ggcttctaag
    16561 ttagccctaa aagcagtttc ttctggatga tgtacataag attatgctaa ttgtttcagt
    16621 tttcctggtt ggaaacctga aaagacttca gttggtgttt ggataacagg agctgcgcta
    16681 aaaccgagct ctttaacttg atcgacgtac tcaggttgct catcaagatt gatttcacga
    16741 taagagacat tattactgtc caagaaacgc ttggtcattt tacattggac acaattgttt
    16801 ttagaataaa cggttaccat tgtgtaactc ctcttcaaaa tttaatacta tcttagtata
    16861 tcagaaaata aaattttgtc aatgatttga actaaatata gtggtgttct tttgttgttt
    16921 ttatatataa acacaatata tagtgtttat attgtgaaat agcaatgatt atcctataaa
    16981 ttgtttttaa agaaactata tcctgtgttt tgttatctag gatagaagat tttcagcaag
    17041 ttatctgaaa ggaaattgaa ggaaaatcca gaaaatgctt gaaaaaaatc ctagaagatg
    17101 gtataatact aaattgtaag ggttatcaca tataactcaa aaaaagaaag aacaaaagga
    17161 gagtcaaact atggcttcta aagatttcca cgtagtggca gaaacaggta ttcacgcacg
    17221 tccagcaaca ttgttggtac aaactgctag caaatttgct tcagatatca ctcttgagta
    17281 caaaggtaaa tcagttaacc ttaaatcaat tatgggtgtt atgagtcttg gtgttggcca
    17341 aggtgctgac gtaactatct cagctgaagg tgcagatgca gatgacgcta tcgctgcaat
    17401 ctcagaaaca atggaaaaag aaggattggc ataagggaaa tgacagaaat gcttaaagga
    17461 atcgcagcat ctgacggtgt tgcagttgca aaagcatatc tactcgttca gccggatttg
    17521 tcatttgaga ctattacagt cgaagataca aacgcagaag aagctcgcct tgatgccgct
    17581 ctacaggcat cacaagacga gctttctgtt attcgcgaga aagcagtagg tacgctcggt
    17641 gaagaagcag ctcaagtttt tgaagctcac ttaatggttc ttgctgatcc agaaatgatc
    17701 agccaaatca aggaaactat ccgtgcgaag aaagtgaatg cagaagcagg tctgaaagaa
    17761 gttacagata tgtttatcac tatctttgaa ggcatggaag acaacccata catgcaagaa
    17821 cgcgcagcgg atatccgcga cgtgacaaaa cgtgtattgg caaaccttct tggtaagaaa
    17881 ttaccaaacc cagcttctat aaatgaagaa gtgatcgtga ttgcacatga cttgacacca
    17941 tctgatacag ctcaattgga caaaaacttt gtaaaagctt ttgtaaccaa cattggtgga
    18001 cgtacaagcc actcagctat catggcacgt acacttgaaa ttgctgctgt attaggtaca
    18061 aacaacatca ctgaaatcgt taaagacggt gacatccttg ctgttaacgg gatcactgga
    18121 gaagtgatta tcaacccaac agatgaacaa gcggcagaat ttaaagcagc tggtgaagct
    18181 tatgcgaaac aaaaagctga atgggcactt ttgaaagatg ctcaaacagt gactgctgac
    18241 ggtaaacact tcgagttggc tgctaatatc ggtactccaa aagacgttga aggtgttaac
    18301 aacaacggtg cagaagctgt tggactttac cgtacagagt tcttgtacat ggattctcaa
    18361 gacttcccaa ctgaagatga gcagtatgaa gcatacaagg ctgttcttga aggaatgaac
    18421 ggtaaacctg ttgtcgttcg tacaatggat atcggtggag ataaggaact tccttacttc
    18481 gatatgcctc acgaaatgaa cccattcctt ggattccgtg ctcttcgtat ctctatctct
    18541 gagactggag atgctatgtt ccgcacacaa atccgtgctc ttcttcgtgc gtctgttcac
    18601 ggtcaattgc gtatcatgtt cccaatggtt gcgctcttga aagaattccg tgcagcgaaa
    18661 gcagtctttg atgaagaaaa agcaaacctt cttgctgaag gtgttgcagt tgcggataac
    18721 attcaagttg gtatcatgat cgagatccct gcagcggcta tgcttgcaga ccaatttgct
    18781 aaagaagttg acttcttctc aattggtaca aatgacttga tccaatatac aatggcagca
    18841 gaccgtatga acgaacaagt ttcatacctt taccaaccat acaacccatc aatcctacgc
    18901 ttgattaaca atgtgatcaa agcagctcac gctgaaggta aatgggctgg tatgtgtggt
    18961 gagatggctg gtgaccaaca agctgttcca cttcttgtcg gaatgggctt ggatgagttc
    19021 tctatgtcag caacatctgt acttcgtaca cgcagcttga tgaagaaact cgacacagct
    19081 aagatggaag agtacgcaaa ccgtgccctt acagaatgct caacaatgga agaagttctt
    19141 gaacttcaaa aagaatacgt taattttgat taatcgaaaa gtccctgcaa ctcagttaca
    19201 gggacttttt tgatatttta aaaagaattt tcaagaaaat ctttcttata gaaagtccaa
    19261 ccttgaaaaa gtagtagtca gaacaaaaaa tacttaaatg gttcataaaa ttcttgacaa
    19321 gttggagatt taggagtaaa ctgttaacca gttaagtaat agagaggagt ttctgcaatt
    19381 tagaaatgaa ttgcaactag aaatatcaaa tagaaagaga gtttcgatga aaattaataa
    19441 gaaatacctt gttggttctg cggcagcttt gattttaagt gtttgttctt acgagttggg
    19501 actgtatcaa gctagaacgg ttaaggaaaa taatcgtgtt tcctatatag atggaaaaca
    19561 agcgacgcaa aaaacggaga atttgactcc tgatgaggtt agcaagcgtg aaggaatcaa
    19621 tgctgagcaa atcgtcatca agataacaga ccaaggctat gtcacttcac atggcgacca
    19681 ctatcattat tacaatggta aggttcctta tgatgcgatt ttcagtgaag aattactcat
    19741 gaaagatcca aactataagc taaaagatga ggatattgtt aatgaggtca agggtggata
    19801 tgttatcaag gtagatggaa aatactatgt ttaccttaag gatgctgccc acgcggataa
    19861 cgtccgtaca aaagaggaaa tcaatcgaca aaaacaagag catagtcaac atcgtgaagg
    19921 tgggactcca agaaacgatg gtgctgttgc cttggcacgt tcgcaaggac gctatactac
    19981 agatgatggt tatatcttta atgcttctga tatcatagag gatactggtg atgcttatat
    20041 cgttcctcat ggagatcatt accattacat tcctaagaat gagttatcag ctagcgagtt
    20101 ggctgctgca gaagccttcc tatctggtcg gggaaatctg tcaaattcaa gaacctatcg
    20161 ccgacaaaat agcgataaca cttcaagaac aaactgggta ccttctgtaa gcaatccagg
    20221 aactacaaat actaacacaa gcaacaacag caacactaac agtcaagcaa gtcaaagtaa
    20281 tgacattgat agtctcttga aacagctcta caaactgcct ttgagtcaac gacatgtaga
    20341 atctgatggc cttgttttcg acccagcgca aatcacaagt cgaacagcta gaggtgttgc
    20401 agtgccacac ggagatcatt accacttcat cccttactct caaatgtctg aattggaaga
    20461 acgaatcgct cgtattattc cccttcgtta tcgttcaaac cattgggtac cagattcaag
    20521 gccagaacaa ccaagtccac aaccgactcc ggaacctagt ccaggcccgc aacctgcacc
    20581 aaatcttaaa atagactcaa attcttcttt ggttagtcag ctggtacgaa aagttgggga
    20641 aggatatgta ttcgaagaaa agggcatctc tcgttatgtc tttgcgaaag atttaccatc
    20701 tgaaactgtt aaaaatcttg aaagtaagtt atcaaaacaa gagagtgttt cacacacttt
    20761 aactgctaaa aaagaaaatg ttgctcctcg tgaccaagaa ttttatgata aagcatataa
    20821 tttgttaact gaggctcata aagccttgtt tgaaaataag ggtcgtaatt ctgatttcca
    20881 agccttagac aaattattag aacgcttgaa tgatgaatcg actaataaag aaaaattggt
    20941 agatgattta ttggcattcc tagcaccaat tacccatcca gagcgacttg gcaagccaaa
    21001 ttctcaaatt gagtatactg aagacgaagt tcgtattgct caattagctg ataagtatac
    21061 aacgtcagat ggttacattt ttgatgaaca tgatataatc agtgatgaag gagatgcata
    21121 tgtaacgcct catatgggcc atagtcactg gattggaaaa gatagccttt ctgataagga
    21181 aaaagttgca gctcaagcct atactaaaga aaaaggtatc ctacctccat ctccagacgc
    21241 agatgttaaa gcaaatccaa ctggagatag tgcagcagct atttacaatc gtgtgaaagg
    21301 ggaaaaacga attccactcg ttcgacttcc atatatggtt gagcatacag ttgaggttaa
    21361 aaacggtaat ttgattattc ctcataagga tcattaccat aatattaaat ttgcttggtt
    21421 tgatgatcac acatacaaag ctccaaatgg ctataccttg gaagatttgt ttgcgacgat
    21481 taagtactac gtagaacacc ctgacgaacg tccacattct aatgatggat ggggcaatgc
    21541 cagtgagcat gtgttaggca agaaagacca cagtgaagat ccaaataaga acttcaaagc
    21601 ggatgaagag ccagtagagg aaacacctgc tgagccagaa gtccctcaag tagagactga
    21661 aaaagtagaa gcccaactca aagaagcaga agttttgctt gcgaaagtaa cggattctag
    21721 tctgaaagcc aatgcaacag aaactctagc tggtttacga aataatttga ctcttcaaat
    21781 tatggataac aatagtatca tggcagaagc agaaaaatta cttgcgttgt taaaaggaag
    21841 taatccttca tctgtaagta aggaaaaaat aaactaatga aaaatgaaag tctcgataaa
    21901 gaggctttca tttttattat gtatatatgt aaaattcttg acaagcaata ttaaaaagag
    21961 taaactatta actagttaat taaccggttt attactttat agtgaatcaa atatacttaa
    22021 gaaaagagga aagaatgaaa atcaataaaa aatatctagc aggttcagtg gcagtccttg
    22081 ccctaagtgt ttgttcctat gagcttggac gttaccaagc tggtcaggat aagaaagagt
    22141 ctaatcgagt tgcttatata gatggtgatc aggctggtca aaaggcagaa aacttgacac
    22201 cagatgaagt cagtaagagg gaggggatca acgccgaaca aattgt
//
LOCUS       DAVAGB010000035        21258 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVAGB010000035 DAVAGB010000000
VERSION     DAVAGB010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21258
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.035"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            <1..288
                     /locus_tag="VQO19_001486"
     CDS             <1..288
                     /locus_tag="VQO19_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET1349725.1"
                     /translation="ETMTSDFFEAWFQKFLLPTLTTPSVIIMDNARFHRMGKLELLCE
                     EFGHKLLPLPPYSPEYNLIEKTWAHIKKHLKRVLPSCNTFYEALLSCSCFN"
     gene            188..634
                     /locus_tag="VQO19_001487"
     CDS             188..634
                     /locus_tag="VQO19_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET1349726.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFTRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVDHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(772..2076)
                     /gene="eno"
                     /locus_tag="VQO19_001488"
     CDS             complement(772..2076)
                     /gene="eno"
                     /locus_tag="VQO19_001488"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HET1349727.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2240..2686
                     /locus_tag="VQO19_001489"
     CDS             2240..2686
                     /locus_tag="VQO19_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HET1349728.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2683..3798)
                     /locus_tag="VQO19_001490"
     CDS             complement(2683..3798)
                     /locus_tag="VQO19_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HET1349729.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENRYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3807..4452)
                     /gene="serB"
                     /locus_tag="VQO19_001491"
                     /pseudo
     CDS             complement(3807..4452)
                     /gene="serB"
                     /locus_tag="VQO19_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084485.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase SerB"
     gene            complement(4511..5944)
                     /gene="glgA"
                     /locus_tag="VQO19_001492"
     CDS             complement(4511..5944)
                     /gene="glgA"
                     /locus_tag="VQO19_001492"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HET1349730.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(5941..7080)
                     /gene="glgD"
                     /locus_tag="VQO19_001493"
     CDS             complement(5941..7080)
                     /gene="glgD"
                     /locus_tag="VQO19_001493"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HET1349731.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7070..8212)
                     /locus_tag="VQO19_001494"
     CDS             complement(7070..8212)
                     /locus_tag="VQO19_001494"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HET1349732.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVTTDED"
     gene            complement(8202..10130)
                     /gene="glgB"
                     /locus_tag="VQO19_001495"
     CDS             complement(8202..10130)
                     /gene="glgB"
                     /locus_tag="VQO19_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HET1349733.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTCQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDIYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNIEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
     gene            complement(10613..12037)
                     /locus_tag="VQO19_001496"
     CDS             complement(10613..12037)
                     /locus_tag="VQO19_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HET1349734.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEATSKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVAEKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(12582..14861)
                     /gene="pulA"
                     /locus_tag="VQO19_001497"
     CDS             complement(12582..14861)
                     /gene="pulA"
                     /locus_tag="VQO19_001497"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HET1349735.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(14973..16931)
                     /gene="ligA"
                     /locus_tag="VQO19_001498"
     CDS             complement(14973..16931)
                     /gene="ligA"
                     /locus_tag="VQO19_001498"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HET1349736.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTNLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(17024..18202)
                     /locus_tag="VQO19_001499"
     CDS             complement(17024..18202)
                     /locus_tag="VQO19_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET1349737.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLQSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(18282..19145)
                     /locus_tag="VQO19_001500"
     CDS             complement(18282..19145)
                     /locus_tag="VQO19_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET1349738.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGLALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(19148..21049)
                     /locus_tag="VQO19_001501"
     CDS             complement(19148..21049)
                     /locus_tag="VQO19_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET1349739.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTDKQLR
                     QMELEMGEKSGEDLDKLMSDYDHLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKVTAEMSQTEEASTSNQAKEASPVNDYQVQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
BASE COUNT         6426 a         4660 c         3757 g         6415 t
ORIGIN      
        1 gagacgatga cgagcgactt ttttgaagct tggtttcaga agtttctctt accaacatta
       61 accacaccat cggttattat tatggataat gcaagattcc atagaatggg gaagctagaa
      121 cttttatgcg aagagtttgg gcataaactt ttacctcttc ctccctactc gcctgagtac
      181 aatcttattg agaaaacatg ggctcatatc aaaaagcacc tcaaaagggt attaccaagt
      241 tgcaatacct tttacgaggc tcttttgtct tgttcttgtt tcaattgact atataaattg
      301 tctaagcgaa acaaccgata agaattggca caaaagcgac cgtatttttg ttaccaatac
      361 aggaaaacca gttcatagtt ctatcttgag caagtctctc cagcgagcaa acgaacgcct
      421 taaaaaacca attcccaaac atctgtcccc tcacatcttc agacacacca ctattagcat
      481 cttatcagaa aataaaattc ctttaaaaac aatcacggac agggttgatc attccgactc
      541 tgaagtcact acttccatct acacccacgt cacaaagaac atgaaagatg aagcaatcaa
      601 tgtactggat aaagttatga aaaagatttt ttaaaaagtt ttgtcccttt tttgccctct
      661 aaatacaaaa atagcccttc ggataaaatc cgaggggcta gaaacgttgt taaatcaacg
      721 gccgaacttt tgaatttcat ggttcgggat aaaatagttc actgaactat tttatttttt
      781 aaggttgtag aatgatttca atccacgata ttcagctact tcaccaagtt ggtcttcgat
      841 acgaagcaat tggttgtatt tagcgatacg gtctgtacgt gaaagtgaac cagtcttgat
      901 ttgtcctgcg ttagttgcaa ctgcgatatc agcgattgtt gaatcttcag tttcacctga
      961 acggtgtgat acaacagcag tgtaaccagc ttctttagcc atttcgatag cttcaaaagt
     1021 ttcagtaaga gtaccgattt ggttaacttt gataaggatt gagttagcag caccttcttg
     1081 gataccacgt gcaaggtagt cagtgtttgt tacgaagaag tcgtcaccaa caagttgtac
     1141 tttcttacca agacgttcag taagagcttt ccaaccatcc cagtcgtttt catccatacc
     1201 atcttcaata gtgatgattg ggtatttgtt aaccaattct tcaaggtagt cgatttgttc
     1261 tgcagatgta cgaacagcag caccttcacc ttcaaattta gtgtagtcgt aaactttacg
     1321 ttctttatcg tagaattctg atgaagcaca gtcaaatccg ataaatacgt ctttacctgg
     1381 tacatatcca gcagcttcaa tcgcagcaag gatagtttca acaccatctt cagttccttc
     1441 gaaacgagga gcgaatccac cttcgtcacc tacggcagtt tccaaaccac gtgatttaag
     1501 gattttctta agagcgtgga agatttcagc accgtaacga agggcttctt taaatgttgg
     1561 cgcaccaact ggcaagatca tgaactcttg gaaagcaatt ggagcgtcag agtgagaacc
     1621 accgttgatg atgttcatca ttggagttgg aagaacttta gtgttgaatc caccaagata
     1681 gctgtaaagt gggatttcaa ggtagtcagc agcagcacga gctacagcga tagacacacc
     1741 gaggattgca ttcgcaccca atttaccttt gttaggagta ccgtcaagtg cgatcatagc
     1801 acggtcaata gcttgttgat cacgtacatc gtagccaatg atagcttcag caatgatgtt
     1861 gtttacgttg tcaacagctt tttgtgtacc aagaccaccg taacgagatt tgtcaccgtc
     1921 gcgaagttca actgcttcgt gttcaccagt agaagctcct gatggaacca taccacgtcc
     1981 gaaagcacct gattcagtgt aaacttctac ttcaagtgtt gggttaccgc gtgagtctag
     2041 gacttcgcga gcgtaaacat cagtaataat tgacattttt tactctcctt atgagttaaa
     2101 ttttttacac ctctataata ccttaaaacc cctccttttt caagaaaaaa cgttatcttt
     2161 gtgcaacttt tccttaactt tataaagtaa tcgctttctt ttgtctgttt tattctaact
     2221 tttatgatat actgttttca tgacagattt atcaaaacaa ttacttgaaa aagctcatgg
     2281 tgggttaaaa ataaatccgg atgagcaaag acgctatctt ggtacttttg aggaaagagt
     2341 tcttggatat gtagatattg acacagcaaa tagccctcag ttagaaaaag gctttttatt
     2401 tattttagaa aaccttcagg aaaaagcaga gccactattt gtgaagattt caccaactat
     2461 cgaatttgat aagcaagttt tctacttaaa agaagcaaaa gaaactgata gtcaagccac
     2521 catagtatct gaagagcata ttacttctcc ttttggcctg gttattcata gcaatgcacc
     2581 agttcaagta gaagaaaaag accttcgact tgcttttcca aaactttggg aagttaaaaa
     2641 ggaagaacca gccaaaacat ccttatggaa gaaatggttt agctaaatct tgcacatatt
     2701 taataagtgc ccaatattgg cagccgtgcg ctccagatag agactggcat ttttcaaact
     2761 atcttctaaa ggttcacttt tctccaaaat agaaaagaca gcttggatat tttcaaatgg
     2821 taggggaggt aaatcttcag caagactacc gcaaatagca ataacaggaa ctccaacagg
     2881 ggttcttttt gcaacaccta taggcgcttt cccagcaaag ctttgactat caagtcttcc
     2941 ttctccaaca acaaccaagt cagcatctga aactttctta tcaaagttga ttaagtccaa
     3001 gcaggtatca attccagaca cgatacttgc ctgagcaaag gcacacaaac caccagcaag
     3061 gcctccacct gctcctgctc ctttaatttc taatgttgca ggtgagaatt tttcataaaa
     3121 atcttggatc gcctgatcta ctactgcaaa catagtcgga tgtagacctt tttgattgcc
     3181 aaaagtgtaa gtcgcacctt gatgaccaca taagggactc acgacatctg ctaaaatatg
     3241 aatttgaaca ccttcaggaa ttttatagcg attttctgtt gaaacagaag ctaagtttaa
     3301 taaggattga ccggaagcag gcaagacatt tccatcccta tcataaaatt gataacctaa
     3361 accagcagca atccccagtc ctccatcatt actggccgtg ccaccaacac cgatataaat
     3421 atctttaatc cctttagaaa tgagatggag aatcaactct ccaataccac aagtttggat
     3481 ttgaagtgga tttcgtttct ctagcggaat ttttccaaga ccaaccaagt cagctacttc
     3541 aaatagtgcc agttcccctt tttgaaaata gcgcatggct tctttttgtc caaaagggtc
     3601 tgtcacttgg atccattttt cttttaggtc aagagaatgt cggatagcat ctacagtacc
     3661 ttctccccca tcaccaacag ggcagaggag acattctaca tctgctatcg attgttggaa
     3721 gcctcttttt attgcttcag ctacctgttg agctgtcaag ctttccttaa acgaatccgg
     3781 tgcaattaca atcttcatat tttccctcat tctaaacagt caatcaaagg aagaacttct
     3841 aaaaaatccc tcttgtcaac atgatgtggt atttcttttt tgagcatttc tttggaacaa
     3901 aaggcgattc ctaactccgc cgacttcaac attaatagat tattgacccc atcaccgatt
     3961 gccaccgttc tttctttaga aagttttagt ttctttctcc atttttccag agtttctttt
     4021 ttgacctggg gacttataat ttgtccaact aattttcctg ttaaaagacc ttctttgact
     4081 tcaagctggt tggcagtgaa ataggcaata ccaagggatt ttgctaatct ctccaactat
     4141 tggtgtaaat ccaccaggca ccagaccaac taggatgcca ttcttttgga gaatagagat
     4201 gaactctggg acatttagcg atagatgaat tgagttgaag acgttatcaa agaccaaaat
     4261 aggaagacct tccaacaagg acactctttt tcttaaactg ctttcaaaga ccaactctcc
     4321 tcgcattgct cgacttgtaa tctgcgaaat ttccgcctca tgacctgcct ctctccctaa
     4381 aagatcaatc acttcttcta ggattaaggt tccatctaca tccaaaacac acaagccttt
     4441 tacttgagac atcagttctc ctctctaaac agcctaaaaa tcgtatgaag tcatcatacg
     4501 attttatcta ttaattaact aaactatggt acaagtcaag gtatgacttg caggctgtat
     4561 cccatgagaa gtcactctcc atagcttgtt tttgtaggtt tctccaaatg tctggatggt
     4621 ttctatacaa gtccaatgct gtttggaaag tccaatttaa ccaataagga gatagattgt
     4681 caaagctaaa gccagtaccg cttccttcga ttggattgaa agcgcgaact gtatctcgca
     4741 agcctccaac ttcatggacc aatggcaagg ttccataacg catagccatc atttgagaca
     4801 agccacacgg ttcaaaacga cttggcatga ggaagaggtc acaagcagcg tagatttcct
     4861 gagcaagttt gacatcaaaa gtgatatttg ttgatagctt gtctgggtaa atctgagcaa
     4921 accatgagaa agctccttca aaggctggat cgccagttcc caaaagaaca atctgaacat
     4981 cttcttgcaa gatatggtga agactttcga ccaccacatc aaaacctttt tgacgtgtca
     5041 aacgagaaac aattcccacc agtggaacgt ctgctctaac aggcaagcca actctttctt
     5101 gcaattttgc cttatttttg gctttcccag acaaatcttc ctgattgaaa tgatagtcta
     5161 aaagagcatc cgtctgagga ttataaagat cagcatcaat cccattcacg ataccagata
     5221 ctttaccaga ctccatttta agaatctgat ccaaattaca tccaaactga ctagtcataa
     5281 tttcatgagc atagctaggt gaaacggttg aaacacggtt cgcatagaga atacctgcct
     5341 tcatccagtt cagacagttg ttccatcgaa gggtgccatc agcgtaacgt tcaaggccaa
     5401 ctccaaacaa atcacccaac attccttctg aaaattgtcc ttggaattct aaattatgaa
     5461 tggttaaaac tgtttcaatg tcctcatagg cttgaatcca acggtatttt tccttcaaca
     5521 agaaaggaat catagctgta tggtagtcat gaacatggag aagatcagga ataaagtcaa
     5581 tcctttccat agcctcaatg gcagccagtt ggaaaaaggc aaagcgttct ccgtcatcaa
     5641 aatcaccgta aacatgacca cggaagaaat aatattgatt gtcaataaag tagaaggtta
     5701 caccatttaa tactgttttc ttaattccac aatactgtct gcgccaacca acgctcacct
     5761 caaaatgaag cacatcttca atctgatttc caaatttagc ctctaccata tcatagtagg
     5821 gtaaaatcac tgcaacttcg tgcccagctt ttaccagtga ttttggaaga gcgccaatga
     5881 cgtctcccaa accacctgtt tttgaaaagg gtgcaccctc tgctgctaca aataaaattt
     5941 tcatgaatga atatcctctg ttactttagc acctttctta accacaactg gatgttctgc
     6001 agttcctcga atcacaacac caggctcaac ttcaacccct ttgtccaaga tagcatattc
     6061 gacctgagcc ccttctccaa taacaacacg agggaagagc aggctatctt taaccaagct
     6121 atccttatgg acatgaatat tacgtgatag aacagaatta gctacttgac cttcaataat
     6181 actaccagag gcaaactgag aagtgcttac cttagatgta ttagcatagt aagttggctc
     6241 ttcgtttttg acctttgtat aaatcttttg gtttggtgag aaaagagaat agaatttttg
     6301 tgattcaagc atatcgatat tcgcttgata ataagattta acagagtgaa tattggctag
     6361 atagcccgtg tactcgtagg cgaaagctcc ctcttttaca gccaaatccc gtaaaacata
     6421 gcgcaatttc tttggatgtt cttttttagc ttcttcttcc aagtgttcaa tcaaccaagg
     6481 tgtatcaacg acaaagatat ctgtagacat attgaacgtt tcagctgttg acttgctatc
     6541 aaagagttta tgagaaagaa catggtctgt ttcatctaca tccaagattg catttacttc
     6601 tgaaatatct ttcttagcta gttttttata aactacagtg ataggctctt ttgttgtact
     6661 atgtaggtgg aaaacttggt tcaaatcaat gttaataaga acatcgcagt tgagggcaac
     6721 cgtttggttt gagccagaac gtttcaaata agtaagaagc tgttggtagt attcttttcc
     6781 aactgtacta ctttctacac gggtattgta aattcctaga tagtaatgac taagaagggt
     6841 tgataagccc cactcgcgtc ctgaacgaat atggtcaaat actgagctga tattatcctg
     6901 ctggaaaata ccaaagacac tacgaacacc tgcattagca aggcttgaaa gtgggaagtc
     6961 aatcaaacga tatttcccac caaatggcaa acttgctact ggacggtggt ccgtcaatgt
     7021 cgacatattg tgaaaaccaa ctgtatttcc taaaatggca gaatatttat caatcttcat
     7081 ctgttgttac ccccactact tcattatatc ctacaacttg tacttcatct gttccatcaa
     7141 tttcgacacc gtcagaaata atcgcacctt caccaataat ggcacgttta atcttagctc
     7201 cttgaccaat gatagctcca ctcatgataa ctgaatcaag gacttccgct ccttcgcgaa
     7261 cttgcgcgcc tgttgaaagg atagaatgtt taacagttcc atcaacgaaa catccgtcta
     7321 caactaatga gtcttctaca tgagcatttg ccccgaggaa gtttggtggt gaaatcaagt
     7381 ttcttgagta aatcttccat tgacggttac gactatccaa ggcattttct ggagaaatat
     7441 actccatgtt cgcttcccaa agtgactcaa tagtaccaac atctttccaa taaccactaa
     7501 attcgtaagc ataaacactt tcacctgact caaggtaatt tggaatgaca tttttaccaa
     7561 agtctgacat gccaaccttg ctcttttcag cagcgactaa catattacga aggcgttgcc
     7621 aatcaaaaat gtagattccc atagaagctt ttgtagattt aggttgagct ggcttttctt
     7681 caaattcaac aatacgattg ttagcatctg tgttcatgat accaaaacgg cttgcttctt
     7741 taagagggac gtctaaaact gctactgtca agctggcatt attatcctta tgagactgga
     7801 gcatatcatc atagtccatt ttgtagatgt gatccccaga caaaatcaag acatactcag
     7861 gattgacact gtcgatatag tcgatatttt ggtaaatagc gtgactagtc ccctcaaacc
     7921 aacgatttcc ttcacttgca gaataaggtt gaagaataga gacacctgaa ttaataccgt
     7981 ctagtcccca gcttgaacca ttcccaatat ggttgttgag agcaagtggt tgatactgtg
     8041 taacgacccc aacattatga atccctgagt tggcacagtt tgatagggca aagtcaatga
     8101 tacggtagcg cccaccaaat tgcacagctg gttttgcgat gctttgagtg agtttaccga
     8161 gacgagttcc ttgcccacca gcaagaatca aagctaacat ttcatttttc attttctact
     8221 cctttttggt ttttatttgt gacggtttta gtagatttca agcgacgttt gattttccat
     8281 acacttgctc ccatagccgg tagagtaaag gttaaggtct gctcataatc tttccatagt
     8341 ccttcttgcg tttgaacagt ttgattatgt tctttccaaa cgcctcccca ctcttccaac
     8401 tcagtattcc atacttcttc gtaaattcct gcaacgggta gtccgattgt aaaatctttc
     8461 cgctcaacag gtaccatgtt aaagatacag actaacattt ctcccttttt acccttacga
     8521 ataaaggaaa gaacactctg gtctcgatta tccgcatcaa tgatttcaat accatcatag
     8581 ctggtatcga tttcccacag acagcgatga tctttgtaaa actggtttag ctgagaagtg
     8641 aaatacttca tcttagcatt cattgggtct tctatgttag accattccaa ctgttcttca
     8701 gatttccatt ctaggaattg accgtattcg ctacccatga agagcaattt cttaccaggg
     8761 tgacaaattt ggtacgtata gagattgcgc aagcctgcaa attgattgta acgatctccc
     8821 cacatcttat gcatcatact cttcttgcca tgaaccactt catcgtgcga gaatggcaag
     8881 agataattct ccttgaaaac atacataaag ctgaaagtca ccaggttaaa gtcatattta
     8941 cgataaatcg gatcttcttc gtagaaacgg aggatatcat tcatccagcc catgttccat
     9001 ttgtagtcaa atcctagacc accaatctct ttcattcccg taatcttggt tgcagacgaa
     9061 ctttcttctg caatcatcat cacatctgga tattctaact taataacttc attcaagcgt
     9121 tgaaggaaat aataaccttc atagttgaga tttccgccat ctttattagg tgtccatgga
     9181 gcatcatcat agtccaaata gagcatgttg ctaacagcat ccacacgaat accatccaaa
     9241 tgatagatat caatccaatg cttaatgcaa gaaattaaga aggactggac ttcatttttt
     9301 ccaaggtcaa aattaagggc accccaacca tggttatgag ccttattatg gtcttggtat
     9361 tcaaaagtcg gtgtcccatc ataataggct aaggcatcat cattgatggt aaagtgacct
     9421 ggtacccagt ccacaataac cccaatatta tgggtatgac actcctcgac aaaatcttga
     9481 aactcctctg gtctaccata ggcatgctct aaagcgaagt aacccataag ctggtacccc
     9541 caactcaaac ctagtgggtg ggacatcaag ggcataaact caatatgagt atagttcatc
     9601 tcaactaggt aaggaatgag ttcatctttc aattgggcaa aactataagg actgccatca
     9661 gaatttcttt tccatgatcc agcgtgaact tcataaatat tgacaggacg ctcttcaaag
     9721 ccccaacgtt ttcttcgtgc cagccaaagt ccatccttcc atttcttctc aggaagctct
     9781 gttaagattg cccctgttcc tggacgagcc tcatacctga cagcaaaagg gtcaatcttc
     9841 atcagttgat gaccattttg acatgtgaca tgatatttgt aaatatgccc ttcttgagcc
     9901 atattggtaa agacttccca gaccccaaaa tcatttctta ccattggaat ctgattttca
     9961 atccagttgg taaaatcacc aaccaagtga acagcctgag cattaggtgc ccaaacacgg
    10021 aaggtatagc catgctctcc atttagttct tccctatgtg ctcctagata atgttggaga
    10081 taaaaatttt cacccgtcat aaaggttttt aatgcttctc tattatccat atactccctt
    10141 tctcctgtaa gcgttttcta tgtttttatt atactacctt tttagagaag attcaagtaa
    10201 attactatac ttctttaatt attttgaaaa tctacaacaa gttcacttac tcgttcaatt
    10261 gtaaatcaat attttttcaa aaaattgcga aaacaccttt ctttttctac tatagtgaaa
    10321 tgaaataaaa catgcgcaaa tcgattaagg aatttaatct aatttctaac aatgtcttag
    10381 aaatcaaagt gtactatttt aacttcaatg tactatatat agtaaaatga aataataaca
    10441 ggacaaatcg atcaggacag tcaaatcgat ttctagcaat gttttagaag tagagctgta
    10501 ctattctagt ttcaatatac tataatacca aaaagttcgt attttttcta taattattat
    10561 tattttatag caaaaaaata aaaccaggaa aacaatttcc tgattttaca cgttatttca
    10621 catcaaaaac aatggatttg acatttgtca tcgcttcaat gctatattta attccttgca
    10681 ctccagctcc agaacctttg acaccaagga atgggaaatt atctggacca cgctgggttt
    10741 tattattaat gtggactgta cctacttcaa gtttttcagc aatttcaaag gcttttttga
    10801 aatcatttgt aaagactgat gattgaaggc cgaattcaga ttcgttggca aaggcaatag
    10861 cttcctctac actagccaca cgaatgattg gtaaaacagg accaaatggc tcttcccatg
    10921 ccactttcat atcttttgta acttggtcaa aaagcactgg ccagaggaga ttgccctcac
    10981 gtttgattgg tgtaagagcc tgagcctctt tttcttgtgc atcctcaatc aagccccaaa
    11041 tgaagtcggc tgaagcattg tcaataacag gtgtaatatc agcattgtca aatggatcac
    11101 caactgttaa tttagaaact tcttcctgaa gcaaagtagc taatttctct gctacacttt
    11161 cgagaacaat gacacgttta atggccgtgc aacgttgtcc tgagtagcta aaggctcccg
    11221 caacaatttg cttggcagca tgttccaaat ctgcatcttc tagtacaaga gctgcatctt
    11281 tcccaccaag ttccaacatg ataggacgca taccagctaa acgaccaata cgttctccaa
    11341 taggagttga acctgtaaag ttgatgaagt tgacttcttt gtgctcaatg atataatccc
    11401 caatttctga accacgacct gtaatggtgt tgaaaacacc tgccggaatc cctgcttctt
    11461 caaatgcttt agccaacaag agtccagaaa tggaaccttg tgttggtggc ttaaacatga
    11521 ccacattccc tgcaatcaag gcaggtgcaa ttttagaagc agataaatta actggataat
    11581 taaagggagc aatcgctagc acgataccaa ctggttcacg acggacaaca gccagtttgt
    11641 ttttacttgt tgcctcaaaa ccaccacctt ccattgcttg tccagtgata cggagacctt
    11701 cctcagcagc ataacgaatc aagtctgctg tacgcactac ttctccaatt gctgctttaa
    11761 tcccttttgc tacttctttg gcaaggatag taccaatttc ttccttatcg cgttctaaaa
    11821 tagctgctgt tttatgcaaa taagccgcac gttcaactgc tgataaagct cgccatgctg
    11881 gcagggctgc acgcgcagct tgcatagcct catcagcttc agtctgagtc atggctggaa
    11941 ctgtacccaa ttcttcttga ttgattggtg aataaatcgt aatttcttgt tcagatgatt
    12001 tccattttcc atttactaaa ttctgatatc ttgtcaaatt cttgtcctcc tgaaaatgat
    12061 taagatatat tttaccaaat tttcagaaaa tcacaaccct ttttgcaaaa tttttgagat
    12121 tattttcaca aacttgattt ttcaaagtat actcaataaa aattaaaaaa atccactacg
    12181 tcaaggcgag gctaatgtgg tttgaagaaa ttttcgaaga gcgtgaatga gtatcatcta
    12241 tagtaaaata aaaaaactga acaatttggt tggggacagc caaaccaatt tctcacaatg
    12301 ttttagaaac aagggtgtgc tattccaatt tcaggctact ataactgtca tagattgctg
    12361 aaacaaagtc taggtaaaag tcttcataat aaaaagaccc cctatcaagt gttcaaaaac
    12421 tttgatagga ggtcttgttt tgtgaaaata tttatcaaat tttctataca agtgagctgt
    12481 tagccaggtt ctttctattc tttcaatttc aatgaatgga ttttttacta atactcataa
    12541 ctgggaattt gtctgtgtaa aaatagcgag atagatggta tttataaaac actcaagaca
    12601 gctagactaa tatcatttaa aacattatct tcttttgagc gactgttggt taccaacata
    12661 gctaaatttc ctgcattttc aaattgatag ggttctgatt tagcattcac aaccaccaag
    12721 agatgttctt tgccgtgaac ttcatagata aggtagccgc tatgttcaat cgcagaatgc
    12781 acaaagacat gatggtaaat ttcatcatag ctagagtaag aaaaggcacc agtttttgtc
    12841 ttcaatcgga tgacttgacg gataaactca atactgtctt gacgctcatt aatcaagttc
    12901 cagttcactt ggttcacact gtcaggagca ttatagctat tcatcgcacg ctctctatca
    12961 tcatgggtca actcaccatt ttcaccagtc gcaaccagtt tggtacgacc aaattcttga
    13021 ccgatttcca taaaggccat cccctgcatg agcagattca tggctgtggc agtttcgacc
    13081 ttgcgcatga tttgctctga actttggtct ggatgaaggg ttgccaataa atcgtgaaga
    13141 ttgtaattgt catgggcttc tacatagtta agcacctgat ttggatgtgt atagcttcct
    13201 aattcacgac ttcctaggat tgctttagct agaattggct ctgtcgcagc accactgaca
    13261 aaacctgact tgatagcacc ataaacttct ccccctttga cagcatcgcg ctgattgtca
    13321 ttaaagaaac caatatttgg catctggtag gcattgtcct tcttggcctt atcataaggg
    13381 gcaagacctg ttcccatatc ccatccttct ccatagagga taatgttgga gtcgatttca
    13441 tccaagcttt gacgaatcat ctgcatggtc ttgacatcat gaatccccat caagtcaaaa
    13501 cggaagccgt caatattata ttcctgcacc cagtatagaa gagaatcaat catatacttg
    13561 cgaaacattt cgtgttcact ggctgtttca tttccaacac ccgttccatt ctggaaggta
    13621 ccatctggat tcatacgata atagtaatca gggactgttg tttggaatgg tgcatcaaca
    13681 actgagaagg tatggttata gactacatcc ataatgactc caatacccgc atcgtgataa
    13741 gcttgaacca tcaccttcaa atcacgaatg acctgagctg gatcatctgg attagttgaa
    13801 aaactagttt ctggcgcgtt atagttttgt ggatcataac cccagttgta ggttacattt
    13861 ccatcctcat cgtattcttt atgacggtct gcaattggtt gcaattgaac ataattgtag
    13921 cccagcttct tgatgtaatc aaaagcagtt gactggccgt attggttaac tgttccagcc
    13981 tgagcagcac ccaagaaagt tcctcgaaga tgttcatcta cacccgatgt aggtgattta
    14041 gtcaaatcac gaatatgcat ttcacagata actgccttac atggattttc caagcgccaa
    14101 gtagcctccg aaccgtgctt aacctcgaag ttttcaactt gcttttctac atggctcaga
    14161 atagctgaac gtttgccatc agggctggtc gcgattgtat aaggatcacg tgtcagtgtt
    14221 tggtgatgag ggaattggac ttgatactga taagtcttac ctaccaaatc ttcttcaaca
    14281 tccaaactcc agacaccgat tgtattgtcc ttatgattat aagagtagct attgcctctt
    14341 ttcatctcaa aagtcttcca aacgggtgca tcattagcag ctgattcata aacgacaact
    14401 tgcacttctg tcgctgtagg tgaccagagg gaaaaatgag cctgattgtc ctctacacgg
    14461 caacccaatt ctccttggta accccaatga tgatcaaaac tagcactgtt aatggcctta
    14521 tcaaaggcaa aaggattttg atttttatag aaaggactgg caatagcagg attttcagag
    14581 taataaatcc tatcatcgcc ttccaaaatc cagacctctg ttaatagggg atagtgatta
    14641 aaacggatag aatattcttt actagtttga cctgtatgaa ccacaaaatt caagctttct
    14701 ataacatgtg aacttgggtg ttcaaagcta aataaagctc caaaataatc ttctttgtag
    14761 gttagcaaat caattcgttg atcctgactt tttacaaagg agcaagtgtc atattctcca
    14821 ttcttacgat ggtaatgaat gcgcataggg tagttataca ttttttattt ttccttttta
    14881 ctttgtttct atttcactaa taaatttttg tcaatctcgt ctcaattaac agacatagtc
    14941 atattctcta aactctgttt ttaaacgatc cattacaaac tttctagcca tgcctcatct
    15001 ctgacctgga taccaagttc ttgtgctttt tgcagcttac ttccagcgtc tgcacctacc
    15061 acgacgaggt tggtcttttt agaaacacta cctgtcactt tggcacccag actttcgagt
    15121 ttacttttag cttctgagcg cttgagtcgt tccaattttc ctgtcaatac cacggtcaaa
    15181 cctgacaagg ccgcatccgc tactaccgtc tgtcctttat agtccagatt gaccccagtt
    15241 tctttcaatt ctctgagcag aatttcagag ccttctgtcg caaaataagt ctgaagactt
    15301 ttggcaatca cgccacctag actttcaata ctagccactt cctctgaatc tgcctgatac
    15361 agattttcaa ttgaatggaa atattgaagt aaaagctgac tagccttgct tccgacatga
    15421 cgaattccca aaccaaataa gagcttctcg gcagaatttt cctttgacgc ttggatagcc
    15481 tgatacagtt tagcagcgga cttttcctta accccctcta aaaggaggaa atcctcttct
    15541 tgcaaacgat aaatatccgc cacatccttg actaaattag cagcaaaaag cttctcaaca
    15601 atagatggac caaggcctgt aatattcata gcatcacgag aagcaaagtg aatcaagcct
    15661 tccatgattt gagcagggca acgcggattg atacaacgta gggccacttc atcttcaaag
    15721 tgcaacaagt cagagttaca acttggacag tttgtaggga tatctagttt ttcttcagaa
    15781 acccgtttgg actctaccac acgtaaaacg gcagggatga tgtcaccagc cttatataca
    15841 atgaccgtat cgtcttttcg gatatctttt tcagcaatat aatctacatt gtgcagggtc
    15901 gcacggctaa cagtcgtacc ggcaagttgt actggtgtta gattagcagt tggagttaca
    15961 acaccggtac ggccaactgt ccagtcaact gataagagtt gagcttcttt ttcttcagca
    16021 gggaacttgt aggctactgc ccactttgga gccttaacgg taaaaccaag ttcttcttga
    16081 cttgctaggt cgttgacctt gattaccact ccatcaatat cgtaaggtag attttcccgt
    16141 tcctgtccta cttcttggat aaaattccag atttcatcta tgttttcagc caagattcgc
    16201 ttaggattga ccacaaaacc tagttgttct aggtacttca aacccttttc ttggctatca
    16261 cgagttgaag ggctggcttc ttgatagaga aacgttgcaa gattacgctt ggcaactact
    16321 gctgtatcca actgacgcag agttcctgct gccgcattac gaggattagc aaattcaggc
    16381 tctccatttt cttggcgcgc ttggttaact tggtcaaagg aagcgcgtgg catgtaacat
    16441 tccccacgaa ctgtgatatc tagttcttct ggcaaagtca aagggatgtc cttaacacgc
    16501 ttgaggtttt ctgtgatatt ttcaccaatt gaaccatctc cacgtgttac cccagcaacc
    16561 aaaatcccct tttcataagt cagcgagata gataagccat cgattttcag ctcacaaata
    16621 taggtcggat gagccacttc cttacgaaca cgcgcatcaa aagcatctag ctcctcacgt
    16681 gaaaaagcat cctgcaaact ataaagagga tactgatgac tgtatttttc aaaaccatct
    16741 aaaaccttgc caccaacacg atgagtcgga ctgtctgcta gcacttgctc tggataagca
    16801 gtttctaact cgaccaactc acggtaaagg cggtcatact cactgtctga aaccgaggga
    16861 ttatcgctgg tatagtactc agtcgcatag cgattgagca aagcgactaa ctcattcatt
    16921 cttttattca taagaccatt ttaccataaa acaagccctc ctcacaaacg agaagggcgg
    16981 aaaaaacact tagtttgaaa ttatttttga aactcaagca accttatatc aatttttcaa
    17041 aatgagttcg aacataaata aacgatatac aagacaagat gataacacca cttccaatta
    17101 tcaggaaaga agagagatgt acactttgca agactgtcat aaatcctttt gcaataggca
    17161 taaatagaat agctaaggta aaaattgtac tcagtactct cccaagaaat tcgctctcaa
    17221 ccttggtttg tacttgagta aaaaagtgaa tattaaaaat cgtcataaac aattcacaaa
    17281 ctaaatttcc agaaaaggaa agaaaagttg gaagtggtaa tcccatcata aaaactccaa
    17341 cacctgtcaa agccagtaaa atcaaaagat tataaatatt agctttaatt ttactagcta
    17401 gaagagcccc aatgatggaa ccaatagccc ccatagttaa aatacttgca taggctcctt
    17461 ctgacccgta aagctgattc gaaaagggaa gtagaaattc aaaagctgca aaaaagaaat
    17521 taacgctgga agctaccagc aaaaggaaga aaatttcttg ctgatgccag atatagtgta
    17581 acccatcctt gatatctaca aaaatatctc tcccagtaaa agcctttttc tcttgaactt
    17641 ttgcttcctc ttttggaagg aaagccacta gaacaaaagc aatgaaaaaa gtcagcgagt
    17701 ctagcagtag cgtcatatgg agacttgcaa actgtaaaac aaggaaggaa agaacaggag
    17761 agctaacacc tacaacctgc aaaaccagct ctaagcgaga attatagatc acaatctcat
    17821 ctttctccac cacttcagtt atgatagctt tattggctgt gcgagaaaag gcaaaagcaa
    17881 tagcctgcac aatgttagca acaatcaaag cgccaatcat ccagctatca ttccttatga
    17941 aagaaatagc cagacaaaga atcccacaaa caagatctgc cgtcattaaa atcttacgac
    18001 gagaaaaacg gtctgaaata actccaccaa agggattgac gagaatagat gtgacgagct
    18061 cagaaatctg atacattcct aaaactgtct gtcctatagt ccccatagaa gccaaccaga
    18121 cactatttcc ataatcatag agcatatttc ccattttatt gatagcccca cggctaatca
    18181 actgcactgc atagcgattc atattaaagc tcctctcaaa ttttgaaact attgtatcaa
    18241 aaccgaaagg agctttttat tttttccctt atttgggaaa attaactttt gacaaatttt
    18301 tcgtagtgtt cctgataata ggctacttgc tctggaagac ctaacacatc aaaaatatgc
    18361 atggcctctt gcatctgctt acagccttct ttacactgtc ctttttgata taaggccaaa
    18421 ccttttaaat aatggaaaac attacgctca taaagcttaa tacctttgtc aataatcttc
    18481 tctgtataag cctcaaaata gttggcatta taaaaagaag aatgctctaa acaatgctgg
    18541 taacaattga gggccaaaat taacactaat ctcttatggc gactaatctc ttggtaaaat
    18601 tcctccctct ccataacttc tctaccaatc cgagtgacat agtctacatc gtagaaacta
    18661 tagaggttac cgaaaagaat caactcatac atggtccatt cttctgtttt gaagagataa
    18721 tctgctacct tatccaaatc atcctgcttc atatcataac tcgcatctct ttgacaaatc
    18781 agaccttgta gcaaaatcca gttcagctca aaataaaggg gagtcgtcga actcttagac
    18841 ttttcaagtt gttctctttg aagcttttga aaacctgcaa tatcgtttga atagtaaagt
    18901 gggataatct gtgccatcat agacacatgt tcatgattat gaaaattcct tgccttatcc
    18961 atgaaatttt cgattgttac atgaatgtta tccaaaatct caaagaaacg ggagactgcc
    19021 aggtcagact ccccaagctc aaagcgagat aactgagagg tagagcagga ttcgcctgct
    19081 gcttccttta aagaataatt tccacttgtt cgaaattcac gaaatacttt tccaagatgt
    19141 tccatcttta cacctgctct gataattctt cccactcaag catagcttct tcctgacgat
    19201 ggctgatttt gtccagctca gcctgtaatt ccatgagttt gtcggcatcg tttgtttcca
    19261 acatttgttc agaaatggct tggctttgac tttctagctc ttcaatttca gcttctagac
    19321 tttcgatttg tcgcatgagt ttgcgaactt ctttttgact ttctttctgg acctgatagt
    19381 cattgactgg acttgcttcc tttgcttgat tgctagttga agcttcctca gtctgactca
    19441 tttctgctgt tactttcttc tcaacatagt agtcgtaatc tccaaggtag agagttgaac
    19501 cattctcaga caattccaaa acatgagttg ccacacgatt gataaagtaa cgatcatgac
    19561 tgacaaacag caaggtacca tcaaagtcaa tcaaggcatt ttctagcact tccttactat
    19621 caatatccaa gtggttggtc ggctcatcca gaatcaaaaa gttattgttt tccatagaca
    19681 atttagctaa aagcaaacga gctttttcgc caccagatag catgccgact gattttttaa
    19741 catcatctcc tgagaaaagg aaggctccaa gacggttgcg gatttcaact tctggtgtca
    19801 gtttgaaatc attccagagt tcatccagca ccgtattact tggtgtcagc ttgctttggg
    19861 tttggtcata gtaaccaacc tcaacattag cgccaaagcg cttttctccc ttgataaacg
    19921 gaatttgatc cacgattgat ttgataaagg ttgattttcc gataccattg ggaccaacga
    19981 tagcgacagc attcatctta cgaagatcta ggttgatagg ttgtgacaag acttccccgt
    20041 cataaccaat agcagtattt tcaacagtca aaacaacatt gcccgacgtt ttttcagact
    20101 ggaaggtcat gttggctgct ttcttgccag cttcaggctt gtccaaacgc tccatttttt
    20161 ctagttgttt acggcgagat tgagcacgtt tagtcgttga agcacgaact agattgcgat
    20221 tgacaaagtc ttccagagca gcgatttcct tctgttgctt ttcatagttt tttgcctcag
    20281 tagctagctt ttgctccttc aattcgacaa aacgagagta attccccaca tagcgatcca
    20341 aggaatgctt ggtcaaatct agcgtaattg tcgcaacctt gtccaagaaa taacggtcgt
    20401 ggctgacgat aatgagggca ccgctatagt ttaccaagta attctctagc caggagatgg
    20461 tttcaatatc caagtggtta gttggctcgt ccaagaccaa gagattgggc ttttcaagga
    20521 gcattttagc tagagccaaa cgagtatttt gaccacctga aagttcagct attttcatct
    20581 gccacataga ctcgtcaaac ttgaatccat tcaaaatcgc tcgaatatca gcttcatagg
    20641 taaagccgcc tgcttggcga aaattctcag ataagtggtc gtaatctgac atcagtttat
    20701 ccaaatcctc accagacttt tcacccatct ccaactccat ctgacgaagt tgtttatctg
    20761 tccgacgtaa gtcattaaag acatgaagca tttcatcgta gatggtattt tcagactcaa
    20821 aacggctatc ttgggctagg taagacagag aaatatcttt tttcttattg atttctccgc
    20881 tagttggctc ctcttctcca actaaaatct tcaaaagagt agacttacct gcaccatttt
    20941 tcccaacaag ggcaatccga tctcgttcat caacctgcag gttgatatta tcgaaaagaa
    21001 cctctcctgc aaaagaacgt tcaattttat tagcttgtaa aataatcata agagtagtat
    21061 agcatgtttc cctaaggcat tcaagataat cgtaagtctt ttagtacaac ttttataaca
    21121 taaaataaac taaattatgt atattttata ttagattctt cactatcttg ttggattttc
    21181 taaccagcta atcttgtttc aaatagttat cgcacaagcc tattatttaa ttcttttcat
    21241 tatttacgta cgtatagc
//
LOCUS       DAVAGB010000036        20773 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVAGB010000036 DAVAGB010000000
VERSION     DAVAGB010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20773
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.036"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            <1..339
                     /locus_tag="VQO19_001502"
     CDS             <1..339
                     /locus_tag="VQO19_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET1349740.1"
                     /translation="KPSEEKPQTEKPEEETPREEKPQSEKPESPKPTEEPEESPEESE
                     EPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAE
                     KLLALLKESK"
     gene            761..1141
                     /locus_tag="VQO19_001503"
     CDS             761..1141
                     /locus_tag="VQO19_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HET1349741.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLVFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQIQLAELEINK"
     gene            1600..2313
                     /locus_tag="VQO19_001504"
     CDS             1600..2313
                     /locus_tag="VQO19_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HET1349742.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAEFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2371..2974
                     /locus_tag="VQO19_001505"
                     /pseudo
     CDS             2371..2974
                     /locus_tag="VQO19_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3110..3763
                     /locus_tag="VQO19_001506"
     CDS             3110..3763
                     /locus_tag="VQO19_001506"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HET1349743.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3773..4237
                     /locus_tag="VQO19_001507"
     CDS             3773..4237
                     /locus_tag="VQO19_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET1349744.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAVREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4250..5518
                     /locus_tag="VQO19_001508"
     CDS             4250..5518
                     /locus_tag="VQO19_001508"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HET1349745.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKVPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5532..5792
                     /locus_tag="VQO19_001509"
     CDS             5532..5792
                     /locus_tag="VQO19_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349746.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5803..7164
                     /gene="pdrM"
                     /locus_tag="VQO19_001510"
     CDS             5803..7164
                     /gene="pdrM"
                     /locus_tag="VQO19_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HET1349747.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAVFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            7318..8286
                     /locus_tag="VQO19_001511"
     CDS             7318..8286
                     /locus_tag="VQO19_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HET1349748.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8302..9294
                     /locus_tag="VQO19_001512"
     CDS             8302..9294
                     /locus_tag="VQO19_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HET1349749.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFDPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKNAIRKTYNKE"
     gene            9512..10555
                     /locus_tag="VQO19_001513"
     CDS             9512..10555
                     /locus_tag="VQO19_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HET1349750.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDIIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10619..12304
                     /gene="lpdA"
                     /locus_tag="VQO19_001514"
     CDS             10619..12304
                     /gene="lpdA"
                     /locus_tag="VQO19_001514"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HET1349751.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EENGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVSGMESSLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVAAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            12368..13357
                     /locus_tag="VQO19_001515"
     CDS             12368..13357
                     /locus_tag="VQO19_001515"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HET1349752.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDALRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13430..14500)
                     /gene="xerS"
                     /locus_tag="VQO19_001516"
     CDS             complement(13430..14500)
                     /gene="xerS"
                     /locus_tag="VQO19_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HET1349753.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETAGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(15084..16634)
                     /locus_tag="VQO19_001517"
     CDS             complement(15084..16634)
                     /locus_tag="VQO19_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HET1349754.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16650..17429)
                     /locus_tag="VQO19_001518"
     CDS             complement(16650..17429)
                     /locus_tag="VQO19_001518"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HET1349755.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(17416..18267)
                     /gene="ylqF"
                     /locus_tag="VQO19_001519"
     CDS             complement(17416..18267)
                     /gene="ylqF"
                     /locus_tag="VQO19_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HET1349756.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQEIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(18349..19815)
                     /locus_tag="VQO19_001520"
     CDS             complement(18349..19815)
                     /locus_tag="VQO19_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET1349757.1"
                     /translation="MYYVTKTNSKGQPLYQVVEKCKDPLTDKWRTVTVSYTRNTSRAR
                     KQAEREVMDKIEKLTSSLESQYNPEMITTFGELKESWFQTWCVSVKPQTIKREELVIE
                     RLGKIIGDEFLLDRITPLLMKNCLNKYLDKYDASPSTMTHIKSTCNKIFNHGVLYNVI
                     KYSPMTAVKIDVPLEKKREARKRLDAKFLEIHELQAFFDVLGQCRNASYYDLAIVLLL
                     TGIRIGEAAFLPSDVDFDKGILHIDKALQYHDLKVDEFYFDTTKTVNADREVALPIAA
                     SEAIQRAIKRNQEFEAYMEQNPSPAFKKCDSVFQTEYGSPITSHSFRQVLKRVEWVKH
                     VTPHSFRHMHISYLQSNEMHIAVKDIMTRVGHANFETTMGYTHNISRSQENTVTALNQ
                     FVEKHNFHFKELKSYTCKYSRMIEQFIETCDDNNKVELSVDEFKDLLHLGSRYSPKHI
                     VSNLLLKIKKDIVKYHPQFDIKIVKLSENQIKGFSISW"
     gene            complement(19891..20124)
                     /locus_tag="VQO19_001521"
     CDS             complement(19891..20124)
                     /locus_tag="VQO19_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000693750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET1349758.1"
                     /translation="MEIKYVSVENSVAEWADKKSILKRWEGLNLYTLNRWIKEMRENK
                     RFSLYVINPTHKLVFINLEGFECFLRWKQKRTK"
     gene            complement(20426..20649)
                     /locus_tag="VQO19_001522"
                     /pseudo
     CDS             complement(20426..20649)
                     /locus_tag="VQO19_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
BASE COUNT         6303 a         3887 c         4270 g         6313 t
ORIGIN      
        1 aaaccaagcg aggagaaacc tcagacagaa aaacctgagg aagaaacccc tcgagaagag
       61 aaaccgcaaa gcgagaaacc agagtctcca aaaccaacag aggaaccaga agaatcacca
      121 gaggaatcag aagaacctca ggtcgagact gaaaaggttg aagaaaaact gagagaggct
      181 gaagatttac ttggaaaaat ccaggatcca attatcaagt ccaatgccaa agagactctc
      241 acaggattaa aaaataattt actatttggc acccaggaca acaatactat tatggcagaa
      301 gctgaaaaac tattggcttt attaaaggag agtaagtaaa ggtagcagca ttttctaact
      361 cctaaaaaca ggataggaga acgggaaaac gaaaaatgag agcagaatgt gagttctagt
      421 tctcattttt ttcatgaaaa tgtgcaaaat atagtagatt gaaactagaa tagtatacct
      481 ctacttctaa aacattgtta gaaatcgatt tgactgtcct gttcttattt cattttacta
      541 tatcttaaca gatagtgtaa ataaagataa actatttact ggctaattaa tcagttaaac
      601 actagttaag gagtaatgat gaaaaaaaga acaatactat tattgacggc cagtctgtta
      661 gctcttgtct taggagcatg tggtttcttg gacatattga tcctggatca ttctcatcag
      721 gattactctt tactgctatt ttagaaactg gagtggtttg atggaaagta ttggtattgg
      781 tcttgttatc gtttcacatt ccaaacacat tgcagaaggt gttgttgaac tgattagtaa
      841 agtagctaaa gatgttccga ttacttatgt aggaggaacc gagggcggag gaattggaac
      901 gagttttgat caagtagata gggttgtttc cgaaaatcca gcagatactt tacttgtatt
      961 ttttgaccta ggttctgcta aaatgaactt aaaaatggtg actgatttca gtgataaaag
     1021 tatcatcatc aacagggttc caattgtaga aggtgcctat aatgcagctg ctcttcttca
     1081 ggctggtgca gaactgtcag ttattcaaat acagttagcg gagcttgaaa tcaataaata
     1141 aggaatttta ctataactct ttttataggt aagctattga ttatctcaac tataaaatgt
     1201 taagtaaatg atttcaaaat cagaaaggga ttgctttatg cagttccttt ttattttaac
     1261 aggagtgaaa ctatagtgtt tctaaattgt gaatcaatca aaactgattg tgatgggact
     1321 attctagctt tagaatcctt caaaaattaa aatttaaggc aatcaattac ttggaagagt
     1381 atgaaagcat ttagtttata agaattctag gtctagaatt acacatatat ttatgaagac
     1441 ggggtgctcg atagttagta ttgttctatt ctgaaagatt tgagctgtca gttgtataga
     1501 aagtgttcga atttttttta agtgattaaa ttagttaatt gtatgaggtg ctttatgata
     1561 taatgttctt aatgaatttt cagaaaggaa aacctcaaat tgttctacaa atttctactc
     1621 ttcgacctcg accacactct tcttgatttt gatgctgctg aggatgtggc tttgacccaa
     1681 cttctaaaag aagaaggagt tgcggatatt caggcttata aagattatta cgttcctatg
     1741 aacaaggctc tctggaaaga cttggagctg aagaaaatca gtaaacaaga gctggttaac
     1801 acgcgctttt ctcgtttatt tgctcatttt ggacaggaaa aagacggtag ttttcttgcc
     1861 cagcgttacc aattttacct cgcccagcag ggacaaacac tatcgggcgc tcatgatctc
     1921 ttggacagcc tcattgagcg tgattataac ttgtatgctg cgacaaatgg cattactgcc
     1981 attcagacag gacgtttggc tcaatctggt ctagcacctt atttcaatca agtctttatc
     2041 tcagaacagt tgcaaactca aaagccggat gctctctttt atgaaaagat tggccagcaa
     2101 attgctgaat ttagtaaaga aaagacgctg atgattggag attctctaac tgccgacatt
     2161 caaggtggca ataatgcggg gattgacact atctggtata atcctcatca cctcgaaaat
     2221 cacacacaag cccagccgac ttacgaagtc tattcttacc aagacttgct ggattgttta
     2281 gataaaaata ttcttgaaaa gatcacattt taaaggagac gagctaatga ctacaaaaaa
     2341 gctaatatta ctattgaaga gtacattgaa atgtctgaag ttgattttaa tgaagctgtt
     2401 acttatgaat ttacatctga cacttgtcaa ttagcaaata gtatttatca atctcttttt
     2461 aagttttttg ataagaaaaa tttctctggc gatttaattt ttacttggaa atctccatca
     2521 ttagtcaaag aaggggatta tattgggaga agggattcac aagtagataa tcttagagta
     2581 ataggaaata tatttccgaa ttatcttact aatcgaaaat atagcctcaa tatgaatcgt
     2641 aatggctgta tgggagattt tcctcatgac tttttttgat atatacctag atcatgtagc
     2701 aaaatatgcc tacgaacaaa aagttaataa tattaaagag tattatcctt taaaaagagc
     2761 gattttacac caagagaatg cattgtattt tcgatttttt tctaattttg acgacttttt
     2821 agaaaaaaat tatttaaaga ctatatggca agtttctaaa gaaactcctt tttctgaaat
     2881 ggattttaat atgtttaaaa atatttcaga aaagataatc ttcgaaagag gtagtaaaat
     2941 gcttaatgat ttaaaaagta attataaaaa atagccagtc tttataaact gtattcacgt
     3001 attcaaatcg tatatagtcg atttattaaa tctttagata aattgtaaaa agtggtttcc
     3061 atagccactt tttgctataa tagaggcagt aaaaatgaag gagtcagcta tggaacactc
     3121 gtcttggcat gctttgatta aggcgcaatt acctgagggt tatttcggga aaatcaatca
     3181 gtttatggag caggtctatt ctcaggggat tatttatcca cccaaggaaa aggtttttca
     3241 ggctctcttg acaacactgc ttgaagaagt taaggtggta attctagggc aagaccccta
     3301 tcacggacca ggtcaagcgc agggcttgag tttttctgta cctgactcta tcccagctcc
     3361 accatccttg caaaatatct tgaaagaatt gtcagatgat atcggagtta agaaatctca
     3421 tgatttgaca gcttgggctg agcaaggagt cttgcttctt aatgcttgtt tgactgttcc
     3481 tgctggacag gccaatggtc atgctggtca aatctgggag ccttttactg atgctgtgat
     3541 tcaggtggtc aatcatctag atagaccagt cgtttttgta ctctggggag cttatgcacg
     3601 taagaagaag gccttagtta ccaatcctca tcacttgatt atcgaatcag cccatccaag
     3661 tcctttgtcg gtttatagag gattttgggg ttccaagccc ttttccaagg ccaatgcatt
     3721 cttaaaagag acaggacaag agccaatcga ttggcttaga taaggagaaa atatgcctca
     3781 gttagcgacg atttgctaca ttgataatgg gaaagaactg ctcatgctcc atcgtaataa
     3841 gaaacccaat gatgtccatg aagggaaatg gattggtgtg ggtggtaagc tagagagagg
     3901 agagacgccc caggaatgcg cggtgcgtga aatccttgaa gaaacagggc tcaaagccaa
     3961 gccagttcta aaaggtgtca tcacttttcc tgaatttaca ccagatttag actggtacac
     4021 ctatgttttt aaggtgacgg agtttgaggg cgacttgatt gactgcaatg aggggacgct
     4081 agaatgggtt ccctatgatg aggttttgag caagccgact tgggaaggtg accacacctt
     4141 tgttgagtgg cttttagagg ataaaccctt cttttcagcc aagtttgttt atgatgggga
     4201 taaattgttg gatacccaag ttgatttcta tgaataaagg agaaagcaga tgctactaat
     4261 caaaaatggt cgtgtaatgg atcctaagtc tggtttggat caagtttgtg atgtcttagt
     4321 tcaagatggg aaaattatca aaattgcgcc tgagatcacg gaagaaggag cagaaacgat
     4381 tgatgctact ggtcttgtgg ttgctcctgg tttggtcgat attcatgtgc atttccgtga
     4441 acctggtcaa acacataaag aagacattca tactggtgcc ctagcagccg ctgcaggtgg
     4501 ttttactact gtcgtcatga tggctaatac cagtccaacc atttcagacg tggagacttt
     4561 gcaagcagtc ctccagtcag ctgccaaaga gaagattaat gtcaagacag ttgcgaccat
     4621 tactaaaaac tttaatggta aaaacttgac tgactttaag gcacttttag aagctggtgc
     4681 ggttggtttc tctgatgacg gtattccgct tgagagcagt aagattgtca aggaagccat
     4741 ggaggaagcc aaaaaactca atacctttat cagccttcat gaggaagatc caggtttgaa
     4801 cggtgttctt ggctttaatg aaaatattgc tagagaacat ttccatatct gcggtgctac
     4861 tggggtggct gagtacgcta tgatggcgcg tgatgtcatg attgcctatg caactaaagc
     4921 ccatgttcac atccagcatt tgtctaagga agaaagtgtt aaagtagtgg agtttgctca
     4981 ggggttaggt gcagaagtca cagcagaagt agcgccacag catttctcta agacagaagc
     5041 acttctttta acacaaggta gcaatgctaa gatgaatcca ccgcttcgtt tggaatcaga
     5101 ccgtcgtgcc gttatcgaag gtctcaaatc aggtgtcatc acagttattg cgactgacca
     5161 cgcgcctcat catgtagatg aaaaaaatgt tgaggatatt accaaagtac catctggtat
     5221 gactggctta gaaacatccc tgtctctcgg cttgacctat ttagtagaag ctggtgagtt
     5281 gagcttgatg gaattacttg aaaaaatgac atacaaccca gccaagcttt acaactttga
     5341 agcaggttac ttggctgaga atggtccagc agatatcact atttttgatg ccaaggctga
     5401 ccgccttgtg gactcccatt ttgcttccaa agcagctaat tcaccattca tcggtgaaac
     5461 cttaaaaggg caggttaaat ataccatctg taagggacaa atcgtctatc aagcttgata
     5521 ggagttagaa tatgaattat tttcgaaaac gtagggagag acaagcgaaa tctaatagtg
     5581 gaatttactg tcccgcagct aatcgttcca aaattcaata tgaaactaaa gaaaaagctg
     5641 accatgcggt tcaatatgat aacggaggtt tagttagaag ctattattgt cgtacatgtg
     5701 cgtgttggca tactacttca aaatctaata aacctccgct aagtttgaaa aactatggtc
     5761 tgaaactctt tggtttagat aaatcagaat agaaagagaa gtatgtataa gacaaagtgt
     5821 ttacgagaga agttagtatt atttttaaaa attttcttcc caatcctgat ctaccaattt
     5881 gccaattatt ctgcctcttt tgttgatact gcaatgacag gtcaatacaa cactatggac
     5941 ttggctggtg tatctatggc aaccagtatc tggaatcctt tctttacatt tctaacaggg
     6001 attgtgtcag ccttggtgcc tatcattggt caccatcttg gtcgaggcaa aaaggaagaa
     6061 gttgcgtctg atttttacca atttatttat ttggccttgg gcctatctgt ggtcttgctg
     6121 gggatggtac ttttcttggc accaacaatc ttgaatcata ttgggttaga agcagcagta
     6181 gcggcagtag cggttcgcta tctttggttt ttatctatcg ggattatccc cttgttgctc
     6241 tttagcgtca ttcgttcctt gctggattcg ctgggcttga ccaaactgtc catgtacctc
     6301 atgcttttgt tactccctct caatagcgga tttaactatc tcttgattta cggtgccttt
     6361 ggtgttccag aactgggagg ggctggtgct ggtttaggaa catccttggc ctactgggtc
     6421 ttgcttggga tttctgttct ggttttattt aaacaggaga agctcaaagc cttacacctt
     6481 gagaaacgaa ttccacttaa tatggataaa attaaggaag gagttcgttt aggtctgcct
     6541 attgggggaa ctgtcttcgc ggaagtggct gtcttttcag tggttggctt gattatggct
     6601 aagttttcgt ccttgattat agctagtcac cagtcagcta tgaacttttc aagtcttatg
     6661 tacgcctttc ctatgagtat ctcatcggct atggctattg tcgtttccta tgaagtggga
     6721 gccaagcgat ttgatgatgc gaaaacctat attggtctag gaagatggac tgccctcatt
     6781 tttgcggcct tcaccttaac cttcctttac atttttaggg gaaatgtggc cagtctttat
     6841 ggtaacgacc caaaatttat cgatttgaca gcgcgttttt taacttatag tcttttcttc
     6901 cagttagcag atacctttgc ggcgccgctt cagggaattt tgcgggggta taaggataca
     6961 gttattcctt tttaccttgg tttgcttggt tattggggcg tagcaatccc tgtggctacg
     7021 ctatttgatt ccctaacaga ttttggagct tattcttact ggatcggctt gattattagt
     7081 ttgattgtga gtggggcgct ctaccgttgg cgtttaactg tgattatgaa gagatttgaa
     7141 tctttagcaa aatccaaacg ctaaaaagtt tgtgaaaaaa tatccttgac aagaaaatcc
     7201 cttgttttca cggggttttc ttttttattt tgtgaaattt cttttagaaa aactttgaca
     7261 gtatttgcca aaagcggtaa aatagtaagg taagaagaaa gttagaaagg caagaagatg
     7321 tcaactttag ataaaaatct tttgctagaa atgttccgta agatggaaga aatccgtcgc
     7381 atggacttaa aaattgcaca attagtaaag aaagggaaag tgccaggaat gacgcacttt
     7441 tctgttggtg aagaggcagc taacgtgggg gctatgttag ctctcaatcc agatgatctg
     7501 attacctcaa accaccgtgg acacgggcaa gctattgcta aagggattga cctcaacgga
     7561 atgatggctg aaatccttgg taaatacact ggaacctgta aagggaaagg tggatctatg
     7621 catatcgctg accttgatgc tgggaacctt ggtgccaatg gtatcgtagg tggtggtatg
     7681 gggatcgctg tcggtgcagc cctcagtcag caaatgcaaa ataccggtaa aatcgttgtc
     7741 tgcttctttg gagatggtgc gaccaatgaa ggtgttttcc acgaagcagt gaacatggct
     7801 tctatctgga acctgccagt cattttctat tgcattaaca acggttacgg tatctctgcg
     7861 gatatcaaga aaatgaccaa tatagaacat atccatcaac gtagcgccgc ttatggaatt
     7921 cctggaatgt tcatcgaaga tggtaacaat gtcatcgatg tctatgaagg atttcagaaa
     7981 gctgtggacc atgttcgcag tggcaatggt ccagtcttga ttgaaagtgt aacttatcgc
     8041 tggctcggtc actcatcatc tgaccctggt aaatatcgta cgcgtgaaga agtggaattg
     8101 tggaaacaaa aagatccaat cgaaaacctc cgcaattacc ttattgaaaa taacattgca
     8161 agtgccgaag aattggaaga aatccaagcg caagtaaagg aagcagtaga agcttctgtt
     8221 aaatttgcag aggaaagccc attcccaccg cttgaatcag cctttgaaga tatttacgca
     8281 gactaaggag aaagagataa aatggaaaca aaaacaatgt ccttccgtga caccattatc
     8341 cttgctatgt ctgaggaaat gcgtcgcgat gaaaatgtgt tcttgatggg agaagacgtc
     8401 ggtgtcttcg gaggagactt cggtacttct gttggaatgc ttgaagaatt tgatccagaa
     8461 cgtgtccgtg actgtccgat ttctgaagct gccatctctg gagcagcagc aggagcagcc
     8521 atgacaggac ttcgtccaat cgtcgatatg accttcatgg acttctctgt tattgccatg
     8581 gacaatatcg tcaaccaagc tgctaaaaca cgttacatgt ttggtggtaa aggtcaggtt
     8641 ccaatgactg ttcgttgtgc agctggtaac ggagttggct ctgccgccca gcactcacaa
     8701 tctctagagt cttggtttac tcacattcca ggacttaagg ttgtggcacc tggaacacct
     8761 gcggacatga aaggcctgct taagtcttct atccgtgata acaacccagt tattatactt
     8821 gagtacaagt cagaatttaa ccaaaaaggg gaagtgccag ttgatccaga ctacacaatt
     8881 ccacttgggg ttggtgaaat caaacgccaa ggaacggatg taacagttgt tacttatgga
     8941 aaaatgcttc gccgtgtggt tcaagctgct gaagaattag cagaagaagg aatttcagtt
     9001 gaaattgttg acccacgtac ccttgttccg cttgataagg atatcatcat aaactcagtg
     9061 aagaagactg gtaaggttgt tctggtcaac gatgcccaca aaacaagtgg ctatatcggt
     9121 gaaatttcag ctattatttc agaatcagaa gcatttgact atctagatgc accaattcgc
     9181 cgttgtgcag gagaagatgt gccgatgcct tatgcacaaa acctagaaaa tgcaatgatt
     9241 ccaacagttg aaagtatcaa aaatgcaatc cgaaaaactt ataacaaaga atagagttac
     9301 ataagataag ttatgtaaat aaaataaagc tgacgagaaa ctttgtatct tttaggtgca
     9361 gagctcttcg tcattaatat cttagattag agcacgggct aaaagctcgg aaaaaagata
     9421 aatctccttg gcttcatcga agccatcgtc gatttcctat ttttcagtcg cttttgacgc
     9481 cctttgtatc ataaatagaa ttggagaggt catggctgat gacaagctaa gagcgactcc
     9541 tgcagctaga aagttagcgg atgatttagg gataaacctc tacgacgttt ctggctcagg
     9601 tgcaaacggt cgtgtccaca aagaagacgt ggaaacttat aaagacacaa acgtggttcg
     9661 catttcgcca cttgcaaaac gaattgccct cgaacataac attgcttggc aggaaatcca
     9721 aggaaccggt catcgtggta aaatcatgaa gaaggatgtt ttggccctgc ttcctgaaaa
     9781 tatcgaaaac gatagcatca aatctcctgc tcagattgaa aaagtggaag aagtccctga
     9841 taacgtaaca ccatatggtg aaatcgagcg tattccaatg acaccaatgc gtaaggttat
     9901 tgcccaacgc atggttgaat cttacttgac tgcgccaacc ttcaccctca actatgaagt
     9961 tgatatgact gaaatgttgg ctcttcgtaa gaaggttctt gagccaatca tggaagcaac
    10021 tgggaagaag actactgtaa cagaccttct ttcgcttgca gttgttaaga ctcttatgaa
    10081 acacccatac atcaatgctt cattgacaga agatggcaag actattatca ctcacaacta
    10141 tgtcaatctt gccatggcag ttgggatgga taatggattg atgacacctg ttgtttacaa
    10201 tgctgagaag atgagtcttt cagaactggt tgtagccttt aaggatatta ttggccgtac
    10261 cttggatggt aaattggctc caagtgagtt acaaaattca acattcacaa tcagtaattt
    10321 gggaatgttt ggtgttcagt cctttggccc gattattaac caacccaact cagctatcct
    10381 tggtgtcagt tcgacaatcg agaagccagt tgtcgtcaat ggtgaaattg tgattcgccc
    10441 aatcatgagt ttaggattaa ccattgacca ccgtgtcgta gatggtatgg ctggtgctaa
    10501 gtttatgaag gacttgaaag agttgattga aacgccaatc tcaatgttaa tttaagagca
    10561 agagtattca tttttaagat atagataaag gaaggaagac atggccttag aagtaattat
    10621 gccaaaagcc ggcgtggata tgacagaagg acaaatcgtc caatggaata aaaaagtcgg
    10681 agaatttgta aaagaaggag aaatcctttt ggaaatcatg actgataaag tcagcatgga
    10741 attggaagcc gaagaaaatg gatacttgat tgccattctc aaaggagatg gtgaaactgt
    10801 ccctgtaacg gaagttatcg gttaccttgg tgaagaaagg gaaaacatcc caacagctgg
    10861 agcagcatcg ccagaagcta gccctgtacc tgtagcaagt acctcaaacg atgatggtaa
    10921 gagcgatgat gcttttgata tcgttgtgat tggtggaggt cctgctggtt atgttgcagc
    10981 cattaaagct gcccaactcg gcggtaaggt tgcccttgtt gagaaatctg aacttggtgg
    11041 aacctgctta aaccgtggat gtattccaac caagacctac cttcataacg ctgaaattat
    11101 tgaaaatatc ggtcatgctg caaatcgtgg tatcgtgatt gaaaatccta acttcactgt
    11161 tgatatggaa aaacttttag aaactaaatc taaagttgtt aatactcttg ttggtggtgt
    11221 tgcaggactt cttcgtagct acggagttac tgttcataaa ggaattggta caatcactaa
    11281 agacaagaac gtcttggtaa atggttctga attgcttgaa accaagaaaa tcattcttgc
    11341 tggtggttca aaagtcagca agatcaacgt ctctggtatg gaatcttcac ttgtcatgac
    11401 tagtgatgac attcttgaaa tgaacgaagt gccagaaagc cttgttatca tcggtggtgg
    11461 agttgtcggt atcgaactcg gtcaggcctt catgacattt ggttcaaaag tgactgttat
    11521 cgaaatgatg gaccgtatag ttccagctat ggatgcggaa gtttctaaga accttcgctt
    11581 gatccttgag cgtaaaggaa tgaccatctt gactggtact aaactgcaag aaatcattga
    11641 ggaaaatggt caacttcgta tcaaggttga aggaaaagac gatatcatcg caagcaaagc
    11701 tcttctttca attggtcgta tgccagacct tgaaggtatt ggagaggttg agtttgaatt
    11761 ggatcgtggt tgtatcaagg tcaacgaata catggaaact tcagttccag gcatttatgc
    11821 accaggtgac atcaacggta ctaagatgtt ggctcacgca gctttccgca tgggtgaagt
    11881 tgccgctgaa aatgccctta aaggaaatca tgcagttgcc aaattgaatt tgactcctgc
    11941 agccatctac actctccctg aagtagcagc agtaggtttg acagaagaac aagcccgtga
    12001 gaaatacgat gttgccatcg gtaagtttaa ctttgctgct aacggtcgtg ctattgcatc
    12061 tgacgcagct caaggtttcg taaaagttat cgctgataag aaatacggag aaatccttgg
    12121 tgtacacatt attggtcctg cagccgcaga attaataaac gaagcatcaa gcatcatcga
    12181 aatggaaatc actgttgagg aaatgctgaa gaccatccac gggcacccaa cttactctga
    12241 agtgatgtac gaagcgtttg cagatgttct aggaatggcc atccattcac ctaagaaaaa
    12301 ataaaacgaa gatagattag actggaaggt tatttccagt ttctatcata taaagtaaag
    12361 ggatatcatg aaatacatta tcaatcattc aaatgacact gcttttaata ttgccttgga
    12421 agaatacgcc tttaaacacc ttttggatga ggatcaaatc ttcctacttt ggattaacaa
    12481 gccatctatc attgttggtc gtcaccagaa cactatcgaa gaaatcaacc gtgattatgt
    12541 tcgcgaaaat ggtattgagg tagttcgccg tattagtggt ggtggagctg tttaccacga
    12601 tttaaataac ctcaactaca cgatcatctc caaagaagat gaaaataagg catttgactt
    12661 caagagcttc tcaactccgg ttatcaatac cctggctcaa ctcggggtta aagctgagtt
    12721 cacaggtcgt aatgaccttg agattgatgg taagaagttc tgtggcaatg cccaagccta
    12781 tatcaacggc cgtatcatgc accacggttg cttgctcttt gacgttgatt tgtcagtcct
    12841 cgcaaatgcc cttaaggttt caaaagataa atttgaatca aaaggtgtga aatccgtccg
    12901 tgcccgtgta actaatatta tcaatgaatt accaaaaaaa atcacagtcg aaaaattccg
    12961 tgatttactc ttggaataca tgaaaaaaga gtacccagag atgactgaat acgtcttttc
    13021 agaagaagaa ttggccgaaa tcaatcacat caaggatact aagtttggaa cttgggactg
    13081 gaactatggt aaatcacctg aatttaacgt ccgtcgtgga accaaattca ctagtggtaa
    13141 ggttgaagtc tttgctaacg ttactgaatc aaaaatccaa gacatcaaga tttatggtga
    13201 cttctttggt attgaagacg ttgctgcagt agaagatgcc cttcgtgggg tgaaatacga
    13261 acgcgaagat gttcttaagg cgctaaaaac cattgatatc acacgctact tcgctggtat
    13321 tagccgtgaa gaaatcgctg aagcggtagt tggataaatc aaaaagaagt tggccaacta
    13381 accaacttct ttttttgata tttatttaca taatttaaaa tacgtaaaat tataaactat
    13441 ctagagcatt cttttgttca tcattaacaa tatgggtata gaggtcagtg acttgtgtgc
    13501 tagcatgtcc tagttggtga ctgactaaaa cttgtgattt agttgcatca tagagcctag
    13561 ttgctagtgt atggcgcagt ttatggggtg ttacacgcac tttaaaatcc tctgagtatt
    13621 tagcaaccat tttctcaacg ctagaagcat cgatacgatt aggaacacct ctgtagagag
    13681 ttaaaaaaag ggctgtatct gttttttccg ttttatagcg ttgattccga atggccagat
    13741 aattctctaa ataaggttta gcaaaagcag cgacattgac tgagtcacgt ttgccacctt
    13801 ttcgagtaac atcaataacc atcattttta gattgagatc tcttagatct agattaacag
    13861 cttcagataa gcgaacacca gatgccaaga gaagggcaat aatggctaaa tctcgttctt
    13921 tatttttgtt gaatgatgag agagctcgat ttgaaagctg ttgtgggtgc tcttgatcga
    13981 tataagttag aaaacctgct gtttcatcac ctagaaagag tttttgcttg atattttcag
    14041 ctctggcagc aagggtttct ttctttttct tggttgaaac ttttttcatt acattacgat
    14101 agaaataagg ttccccctga tcattttcaa cctcctcggt tagatacttg taaagactag
    14161 aaagtgctga taaggttcga ttgatagttg tctgtgaaac accttgtttt gttgtattag
    14221 cattcagcaa gggacgttca cgtagataaa ggataaagga ttccatgtct ttcttagaca
    14281 tattttccaa aactgataaa ggaatatcgg atattttatc agcgtttgaa ataccagact
    14341 ccaaaaccca gctgaaaaat cggtcatatt ccttaaggta ttcgtacagg gttgtaaaac
    14401 tgtagggcac agccagctta gattggtagt attccagaac ataccagggc atgagttgtt
    14461 ttagtttgtc aattcgttcc agtaaaatct cacgtttcat gtattttctc cataagtaag
    14521 tatactagta gtatagcata gacttgtata tttttcaaga aaattatagt ttttcagaaa
    14581 gatgttatag gagtttttca aagtgataaa aagacttaga cctacaaaca aaacagaata
    14641 aggaaaataa taaaaatctc acccactaaa cttctgttaa tactacataa ctgaagagct
    14701 atataaggag ctatgagata caaaacacat tgtataatag attgaaacta gaatagtaca
    14761 tctggacttc taaaacattg ctagaaattg atttgattgt cctgattgtt ttatcctatt
    14821 tctatttcat ttcactatat aattgctatt gttttctttt tcatgatttt aatcttactg
    14881 tacagatttg atacagtaaa ctcctttcca gctttatgct ttatcatttc taacttaatt
    14941 atagtcttat ttttaataaa gttcaattat ttatatgtaa aattcctcat cagtaaaaaa
    15001 taaccgatct catttctgag aatcggtttt ctaaataaat caagctgagt gtttacataa
    15061 cataaattat gtgaatgatc atgctacaac aacaaatctt tgacttttcc aatttcactt
    15121 tttggaataa ccaggtgaat catatcaccc agatacattc tggttgagcc gttaactgtt
    15181 tggctcttgc cattatggac ttgagttgtg atgaggacgt tgtgtggtaa gttgagttca
    15241 tgaacttgtt tcccagcaat tttatcagaa actggtattt cgataagtgt aacttctcct
    15301 tcgctagata cttcttctgg aagcattttt tccagcatgg cttcatagac tggcgtacct
    15361 ttgagcaaat ccatgataat ataagaaaca agagtgacaa gaccaagtgg catgaggttg
    15421 cgaatatctc ctaccatctc agttacgagg atcatagcgg ttaagggagc ttttgatatg
    15481 gctccaaaat agccactcat tcctagaatg acaaatatag ggaattgctc ttgactgaca
    15541 agtccaagat tgacacagat aacaccaact aaggcaccaa gcaaagaacc aagagctaaa
    15601 atggggagga aaattcctcc tggcagtcca cttccatagc taatcatact ccaaataaag
    15661 cggatcaaaa agtaagctaa taaaacttgg aaactaaaat tttgttcagt taaagaaagg
    15721 acaagctgat ttccgccacc aatgatttga ggtaagaaga ttccgactgg tatgataagg
    15781 ataaaagcca agatgggata ataagctcta tccaaatgga ttttttgacc aatcaagtca
    15841 taaactcttc caacgtttaa tacagctttc tcatagagaa agcctgaaaa tccaaggaaa
    15901 attcccatga cgagatatat ccaatactga tctagggtca tgggaggaat gttatctggc
    15961 atatccaata ctggtgtcaa accgaacatg agtagagaca caaagtttgc tacgatgctg
    16021 gctgctagag ttgagaccca gaaaaagcgc gaaaaatggt gatagacttc ttctacaaca
    16081 aagagaagtg ctgcaatagg agcattaaag gctgcggcta aacctgctgc agctccactg
    16141 gcaatcaagg aacgttcctc tactggactg gatttgagcc acttggcaat tcctttacca
    16201 ccaactgctc caagttgaat actgggtccc tctcgaccca gcatgagtcc actggcaata
    16261 gcaagaatac ctagcacata ttttttccaa agaatgcccc accagttgag ggacatgagg
    16321 cctttcagtt cggcttcgac ttgaggaatt cctgagcctt taatatcttt ttctgaccgt
    16381 gttagtttgg cactgagcca acagatgagt atataaaaca aaaccagtac aaaaagattg
    16441 cgcactaagt acccttgatc ttgataaact ccttgtatca ggtggaagcc tttttcaatt
    16501 aagaaacgaa aggatccgac gataattcca acgatgaggc cgacaatgat tcctcgacca
    16561 acttgggata gtatagtgct ggatgcaaag gcgaattctt tcttagaacg gactatttcc
    16621 gactgttcct ccatggtatt tcctttcaat taactttctt ttttacctaa aaccagtgat
    16681 ttaacgggtt caaagctggt tcggtgaatt ggggtaactc ctagttttgt gaggccttcc
    16741 agatgtttag ctgtgccata tcctgcatta gtagcgaaat catagccagg gaactgctga
    16801 tcgtattctt tcatcaattc atcacgtgtt accttggcta ctatagatgc tgctgcgata
    16861 gagagggagt tggcatctcc tttgataatg gaggtttgtg aaatgggcaa gtccagtttc
    16921 atggcatcaa tcaaaaggtg ctctggttga gggctgagct gggagattgc ttcttgcatg
    16981 gctagtttgg ttgcttcata gatgttgact tggtcgatga cctgattatc tatgatgcca
    17041 attccaatcg acaaggcttg gtcttgaacg gcttggaaaa tctccagatg tttcttttta
    17101 ggaattttct tgctgtcgtt gagaccttta atcttacaat ttttaggtaa aataacggcc
    17161 gcagcgacta caggaccagc aagaggacca cgaccaacct catcaatacc tgcaattaag
    17221 gtcaatcctt gcttataaag ttctttttca taagaaagca tggattccaa gcgcaaattt
    17281 tcatctaatt cagcttgaat ggctctttta cgcttgctga tttccttttg aactcctgag
    17341 cgattatcct tttcaagctc taaaaaaata gggctttcta actccttgac tgtcacaagg
    17401 agttctttga tttctttaat cgttgccatc gaggtcttcc aatgtatcta aggtatagtt
    17461 accgagtttg ccatcacgga cttccttcac gaagagactg taaaaacggt catagtcatc
    17521 acggaaaccg agggcgcggg tcatatccat aataatcaca ggcgcttctt cttcaatttt
    17581 catttgtttg aagcgttcag ccagcttttc tggataatgt tctttgaaat aattgatacc
    17641 aaaaatggta acctcatcca taggaagcaa ctgatccttg atagctccag tcaatgccaa
    17701 cttaagtgca acagtttcat cctcaaactt aggccagaga atccccggtg tatccaagat
    17761 ttccagatct ttattggttt taagccattg ttgacctttt gtgacccctg gcttgtttcc
    17821 aacaacagca atctttttac cagccaaacg gttcatcaga gttgatttac cagcgtttgg
    17881 aatcccgata atcatggtac gcaaggtttc aatctgaatc ccacgttctt tctggcgagc
    17941 aatcttatca gccatgagct tcttggccgc atctgttaca acttttacag tcacttgctc
    18001 tttggagttg atagctagcg tctggatttc ttgtgattca aaatactgac gccattcctt
    18061 ggtcattgct ggatcagcca agtcggcctt gtttaaaatc aagagttttg gtttatcacc
    18121 aacaatcttg gtcaacatag gattttgact agatagaggc aagcgtgcat ctactaaaat
    18181 cgtcacaaaa tcaacaaatt ttaaattttc ctgcacctgt cgacgagctt tagacatgtg
    18241 accaggaaac cattgaatag tagccattgc atttttttcc tttcgtagca agggtttagc
    18301 acccctcatt tattttacta tcgtctaaac accaagcgaa caccaaaact accacgaaat
    18361 ggaaaaacct ttgatttgat tctcgcttaa tttcacaatc tttatatcaa actgtgggtg
    18421 atatttgaca atatcttttt tgatttttaa cagtaaattt gaaacaatat gtttgggtga
    18481 gtaacgtgaa ccaaggtgta ataagtcttt aaattcatca acacttaact ctactttatt
    18541 gttatcatca caagtttcaa tgaattgttc aatcattctc gaatatttac aggtgtaact
    18601 cttcaattct ttaaagtgaa aattgtgctt ttctacaaat tgatttaaag cagttacagt
    18661 attttcttgt gaacgactga tgttatgggt gtagcccatc gtggtttcaa aattcgcatg
    18721 accaactcta gtcataatat cctttacagc tatgtgcatt tcattacttt gaagataact
    18781 aatgtgcata tgtctgaaag aatgaggggt cacatgcttg acccattcaa ccctcttcaa
    18841 aacttgacga aatgagtgag aagttatcgg agaaccatac tcagtttgaa atacactatc
    18901 acactttttg aaagcaggac taggattttg ttccatatag gcttcaaatt cctgatttct
    18961 ttttatagct ctctggattg cttcactcgc tgctattggg agggctacct ctctatcagc
    19021 attgacggtc ttagtcgtat caaaataaaa ttcatcaact tttaaatcat gatattggag
    19081 agccttatca atatgtaaaa tccccttatc aaaatcaaca tctgatggta aaaaagcagc
    19141 ctctccaatc cgaatccctg tcagtaataa tacaatagca aggtcataat agctagcatt
    19201 tctacactgc cctaaaacat caaaaaaggc ttgcaattca tgaatttcaa gaaatttagc
    19261 atcaagcctt tttcttgctt ctctcttttt ctccagaggc acatctattt taacagcggt
    19321 cattggagag tacttaatga cattgtatag cacaccgtga ttaaatatct tgttacacgt
    19381 actttttata tgtgtcattg ttgaaggtga agcgtcgtat ttatccagat atttattaag
    19441 acaatttttc atcagtagtg gtgtaattcg atcgagtaaa aattcatcac cgataatttt
    19501 accaagccgt tctatcacca actcttccct ttttattgtc tggggcttga cagatacgca
    19561 ccaagtttga aaccaactct cttttaactc tccaaaagtt gtaatcattt caggattgta
    19621 ctgactttca agggaagagg tcagtttttc tattttatcc attacctctc tttcagcttg
    19681 ctttcgtgct ctactagtat ttctagtata gctgacagtt actgttctcc acttatcagt
    19741 aagtggatct ttacattttt caaccacttg atacaagggt tgtccttttg aatttgtttt
    19801 agttacataa tacataattt aattcctcga aaagaaataa atcattgttg tatagaataa
    19861 ataactactc tatattatac catgacttcc ttattttgtc cgcttttgtt tccatctcaa
    19921 aaagcattcg aatccctcaa gatttataaa caccagctta tgtgtaggat tgatgacgta
    19981 taaagaaaat ctcttatttt ctctcatttc tttgatccat ctgttaagag tgtagagatt
    20041 caaaccttcc catcgtttca gtatgctttt cttatccgcc cactcagcta ccgaattttc
    20101 aacagatacg tattttatct ccatattatc atcctttcga ataatttctt ctccctccat
    20161 ggcatgactg atggggtcat cataagaatc tcacttactg ctcttttacg acggcagcct
    20221 gaacgttcag aagtatcatt gtatatcatt tgcatcatgg cagatagagt atcgctctat
    20281 tttattggtg attgtccccg ctcctatctt ggcgaatcaa gcaaaactgc tccacaaatg
    20341 aggaaagtac cattttaggc tattcagttg tcaaagggca aataaaaaat ctcactcatt
    20401 ttcaaactct atgaaattga ggagattatt ttctaaagcg aattttatca ggaaaatcac
    20461 agttaatccc aataaatagt ctgtactgac gtcatagaaa tctgagagtt taaccaatac
    20521 atcagccgtc aacgcatgct caccccgttc aattttggca taagctgaat ttgtaaacga
    20581 aagtattgta gctatttgct tttggggcag atcatgatcc tccctcaaat ctctcaaacg
    20641 tctgtacatc tagctttctc ctaagaaaaa gtatagacca tatattgtaa ctatttagga
    20701 tattgtccaa atcggacaac aggaatttta ccatccttta tatagacttt tatttttatg
    20761 tatcaagttt ttt
//
LOCUS       DAVAGB010000037        20170 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVAGB010000037 DAVAGB010000000
VERSION     DAVAGB010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20170
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.037"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(<1..1409)
                     /locus_tag="VQO19_001523"
     CDS             complement(<1..1409)
                     /locus_tag="VQO19_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HET1349759.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPVASQSKAEK
                     DYDAAMKNAEDAKKAVEDAQKALDDAKAAQKKYADDQKKTEEKAKKEKEASKAEQAAN
                     LKYQQELVKYIKYIRENNPKKTEAQKAMDEAEKEHKKKQAEFKKVRLEVIPSAKELEE
                     TRQKAKEAKEKEPELTKKVAEAKAKLEEAEKKVTEAKQKVDAEHAEEVAPQVKIAELE
                     NQVHKLEQKLKEIDESDSEDYVKEGLRAPLQSELDTKKAKLLKLEELSGKIEELDAEI
                     AELEVQLKDAEGNNNVEAYFKEGLEKTTAEKKAELEKAEADLKKAVDEPEKPAEESEN
                     PAPAPKPAPAPAPKPEQPAPAPAPKPEKSADQQAEEDYARRSEEEYNRLTQQQPPKAE
                     KPAPAPAPKPEQPAPAPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMA
                     TGWLQYNGSWYYLNANGAMA"
     gene            complement(1695..1973)
                     /locus_tag="VQO19_001524"
     CDS             complement(1695..1973)
                     /locus_tag="VQO19_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349760.1"
                     /translation="MYNDVIERISLYEFIGDIFYSKIISCCIVASDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            complement(1958..2197)
                     /locus_tag="VQO19_001525"
     CDS             complement(1958..2197)
                     /locus_tag="VQO19_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349761.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            complement(3333..4061)
                     /locus_tag="VQO19_001526"
     CDS             complement(3333..4061)
                     /locus_tag="VQO19_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349762.1"
                     /translation="MSNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IRKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVANHVLTLI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIVYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEYELFKNSK"
     gene            complement(4058..4390)
                     /locus_tag="VQO19_001527"
     CDS             complement(4058..4390)
                     /locus_tag="VQO19_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET1349763.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICAALAMSPGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGKIAYCIGYGALNRGCDISGNPYPWD
                     GFISATVR"
     gene            complement(4446..5348)
                     /locus_tag="VQO19_001528"
     CDS             complement(4446..5348)
                     /locus_tag="VQO19_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349764.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFVIIMLTTIFFWNIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTNTLKDKIQKSDLSYSDLMSLQLYDAMNQSTFLTDSELFEDILSKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIIINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            complement(5556..5930)
                     /locus_tag="VQO19_001529"
     CDS             complement(5556..5930)
                     /locus_tag="VQO19_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HET1349765.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLGRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            complement(6307..7263)
                     /locus_tag="VQO19_001530"
     CDS             complement(6307..7263)
                     /locus_tag="VQO19_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001857891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349766.1"
                     /translation="MGEIGIILLLISTIFCVSPVFIKLDILGTPSHAILTFVLAIPLF
                     YILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFSPGVAVFY
                     KESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLIPFSIIIALVQKLYRIEN
                     QQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIKPYLSESV
                     REQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLNKILEVRPDFV
                     LIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            complement(7445..8503)
                     /locus_tag="VQO19_001531"
     CDS             complement(7445..8503)
                     /locus_tag="VQO19_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349767.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPFSVFTFMFSYILLFVQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNFTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            complement(9384..9596)
                     /locus_tag="VQO19_001532"
     CDS             complement(9384..9596)
                     /locus_tag="VQO19_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349768.1"
                     /translation="MLIVLISVIVALLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIEISGANLLLSFLKKLQIK"
     gene            complement(9604..9975)
                     /locus_tag="VQO19_001533"
     CDS             complement(9604..9975)
                     /locus_tag="VQO19_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0218 family bacteriocin-like peptide"
                     /protein_id="HET1349769.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WIFTNIIDGWDGRRDNQLRIG"
     gene            10612..11475
                     /locus_tag="VQO19_001534"
     CDS             10612..11475
                     /locus_tag="VQO19_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET1349770.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKIHHDLPIEEIRDMLEVVIYIRQHGAGELSDHAEQVVKKLWRKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVEIYYQAKER"
     gene            complement(11661..12131)
                     /locus_tag="VQO19_001535"
                     /pseudo
     CDS             complement(11661..12131)
                     /locus_tag="VQO19_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
     gene            complement(12097..12903)
                     /locus_tag="VQO19_001536"
     CDS             complement(12097..12903)
                     /locus_tag="VQO19_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET1349771.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(13110..13751)
                     /locus_tag="VQO19_001537"
     CDS             complement(13110..13751)
                     /locus_tag="VQO19_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1349772.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(13748..15856)
                     /locus_tag="VQO19_001538"
     CDS             complement(13748..15856)
                     /locus_tag="VQO19_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET1349773.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATVLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(15908..16195)
                     /locus_tag="VQO19_001539"
     CDS             complement(15908..16195)
                     /locus_tag="VQO19_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET1349774.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTVMEYFYGFE"
     gene            16626..16946
                     /locus_tag="VQO19_001540"
     CDS             16626..16946
                     /locus_tag="VQO19_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET1349775.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDNAKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            complement(16999..17571)
                     /locus_tag="VQO19_001541"
     CDS             complement(16999..17571)
                     /locus_tag="VQO19_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET1349776.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            17813..18484
                     /gene="sdaAB"
                     /locus_tag="VQO19_001542"
     CDS             17813..18484
                     /gene="sdaAB"
                     /locus_tag="VQO19_001542"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HET1349777.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            18493..19365
                     /gene="sdaAA"
                     /locus_tag="VQO19_001543"
     CDS             18493..19365
                     /gene="sdaAA"
                     /locus_tag="VQO19_001543"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HET1349778.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            19387..20019
                     /locus_tag="VQO19_001544"
     CDS             19387..20019
                     /locus_tag="VQO19_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET1349779.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
BASE COUNT         6539 a         4043 c         3089 g         6499 t
ORIGIN      
        1 gccatagcgc cgttagcgtt taggtaatac catgaaccgt tgtattggag ccaacctgta
       61 gccatagcgc cattgctgtt gaggtagtac catgaaccgt tgttttgtag ccaacctgta
      121 gccattgaac catcagtatt gtagaagtac cacataccgt tttcttgttt ccagcccgtt
      181 tttggtgcgg gagctggttg ctctggtttt ggtgcaggag ctggagctgg tttttctgct
      241 tttggcggtt gctgttgagt caagcggtta tattcttctt ctgatctacg agcatagtct
      301 tcttcagctt gttgatctgc tgacttctct ggttttggtg caggagctgg agctggttgc
      361 tctggttttg gtgcaggagc tggagctggt tttggtgcag gagctggatt ctcagactct
      421 tcagctggtt tttctggctc atcaactgct ttcttaaggt cagcttcagc tttttctaat
      481 tcagcttttt tctcagcagt agttttctct aaaccttctt taaagtaggc ttctacatta
      541 ttgtttcctt cagcatcttt aagttgaact tcaagttctg caatttcagc gtctaactct
      601 tcaatcttac cactcaactc ttcaagtttc aatagtttag cttttttggt atccaattca
      661 gattgaagag gagcacggag accttcttta acataatctt ctgaatcaga ctcatcaatc
      721 tctttgagct tttgttctag tttatgaact tgattttcca attcagcaat tttaacttga
      781 ggagcgactt cttcagcatg ttctgcatcc actttttgtt tggcttcagt aacttttttc
      841 tcagcttctt ctaattttgc tttagcttct gctacttttt tagtaagttc tggttctttt
      901 tctttagctt cttttgcttt ttgtctagtc tcttctaact ctttcgcgct aggaattacc
      961 tctaatctaa ctttcttaaa ttctgcttgt tttttcttat gctctttctc agcctcatcc
     1021 attgctttct gagcttcagt tttttttgga ttattttcac gtatatattt aatatattta
     1081 accaactctt gttgatattt tagatttgca gcttgttccg ctttagaagc ttctttctct
     1141 tttttcgctt tctcctcagt tttcttttga tcatcggcat actttttctg agcagctttt
     1201 gcgtcatcta aagccttttg agcatcttct actgcttttt tcgcatcctc agcatttttc
     1261 attgctgcat catagtcttt ctcagcttta gactgactag ctacgggagc ttcttctgct
     1321 cttacaaaag taggctgaga cgtaacaaaa ccagccccta agatagcgac gctggctaga
     1381 cttgttaaaa tcattttttt cttattcatc taaatttacc tcttttctga tagtcatttt
     1441 tagactatac ttatattaag tatactcccc ccgtaaatat ttgtcaaatg ttttatatta
     1501 catttttatt acaaatttct atatcataag cttctactcc aaaaagataa agacactact
     1561 tttgcccttt tcgattctct ttttaaacat agcatcatct tccttcattc ctataaaaac
     1621 atttccgatg agagagcttg ttttttaatt tcgttaaaca acaaaaaacg caagcttaag
     1681 cctgcggaca atctttatag ccatttcatt tctttcacat ctgttttacg aactttagca
     1741 tatttcttag cgcttgtaaa atgtagagta actggtttaa atactccgct tttgtctctt
     1801 cgtaaaccta aaactgcgga tcttttattt ttatcctcaa aaaatatgac gtccaatttc
     1861 atagtatttt tagataaatc gctagctacg atgcaacaac ttattatttt agaatagaaa
     1921 atatcaccga taaactcata taaagatatc ctttcgatta catcattgta cataggatat
     1981 ttctaaaatc ttctaaaata aaaacaccag cttgaatagc aggttttgtt tgactagcat
     2041 aatctcgtgt gattttgtat aagtcaaata aatgatgtaa atcagtcaaa caaaaattca
     2101 ctttgaaaat ctctaaatac ttataattcg ttgatacttg acatgttttt ccattgaatc
     2161 tttcttgata gtccaaaata caatcaagta atttcaacga caaactccat attttctcaa
     2221 aataaaaaag cacggggcag ttctcactat tgcccaaagt ggttgattag agtcggcttc
     2281 tctaactccc tatgttgtgc ttattaggct tatcgcaagg gaacagtttt tagctctgcc
     2341 aagccacata gtgtgcttac tactatgtgt ccatgtcacc atgaattgcc gaacggttta
     2401 acgagaaagt atagtagatt gaaacaagat gtgaacaaat cgattaggaa agtcaaatta
     2461 atttctagaa atattttaac agtcataacg gactattcca gattcaatct actatattac
     2521 ttttaggttt atcccaactc aattatgaca tctttttttc aaaagtcaat atatctcact
     2581 cttttcaacg acaagaaaga ggctgataat cgaccaacct ctgtttttag atacagttca
     2641 agtccaaact attctttata gaaaagtccg ataaattcga gcaatagtta acatacttac
     2701 aaatataact cccaaaatag ataacactat tttcacaaaa ctcagttccg aacctatgac
     2761 atatatatga aaaagagggg ctagtcctac acatatatac aataagtagc caacaagttt
     2821 tatctcacca attcctgcaa aaaaaatgtt tcatataacg attctccatt tactccatta
     2881 aatcagtttt attttagact atcataaaac aatcacctct tcaataaaaa ccattggcga
     2941 aatactattc tgaagcattg atagctcaga tttctcagaa taaagctgtc ctaactatcg
     3001 agcagctcaa atacatatat atgagcaatt ctaagcctag aattgctaca aaataaatgt
     3061 tttcaggcta ttctaagtct ttgactgctt aaaattttac attctgaagg attctaaacc
     3121 tagaatagct caaaatcacg agaactaagg tattcgaaac ttcagagtaa tacaatcccc
     3181 ataggaattc tccattctta ttaagcatga ttaaaatgta atcctaacaa gtgatcctcg
     3241 attgtgtttg tagcacttag ttacctagat aagactattt ccctttatca tatctgattt
     3301 taagccgttc taagatttaa cctatgtttc tattacttgc tatttttaaa taattcgtat
     3361 tccttttctt tgataaatgg aactgaaaaa ttagaaaaaa gaagtaaaac cgaaaacaaa
     3421 tagcctgctt tttgaatcac taaaagatat cctaaaaata agtaaactat aacatccaat
     3481 gcgaaaagaa aaaatattct cctcttcatt aaagtgcttg tgtcaaataa tctgatgaat
     3541 aaaaatttta tcgtggtatc tacacaaatt tttatcaaaa agataagagt cagtacatga
     3601 ttagcaactg taccataaag aatagatgga aatatagtta atataaaact agaaatctct
     3661 aaatatttta tccaaggaga ttgagacacc ttgcttctaa actgactaat tttcttatat
     3721 tcgttagtca atttaatatc aaaatctttc ctaattaaat gaaagattgc taactctagg
     3781 ataaaaacac ttattaatac ggtataagtc aaaaaacttt ctgggaaaaa cttattgatt
     3841 aaaatgggga aactcattaa cagaatcgaa tttatggcta gacagataga tactatttta
     3901 tttttcacag aatatagagg tagtgatact attgagtaga taaaagctaa aaaaataagc
     3961 aaaaaatact ccgtgtcatt tataatcgcc ctgaatgata aaaatatata catccaacat
     4021 acgataatgt gtatttttcg aatcttatct acattactca tcttactgtc gcagatatga
     4081 atccatccca aggataaggg ttcccgctaa tatcacaacc tctattaaga gcaccatatc
     4141 caatacagta agctattttt cctgctgctg caccaataag ccaacctcca aggcctccaa
     4201 ctttaatata gtttattagt tttttggtta aaactgcagc tccagctaat gctataaaag
     4261 ttcctggact catagctaaa gctgcgcaaa ttccttgaca agcacgcttg cttaaataag
     4321 ctcccccatc aagatacatc atttcttctt catcaatcac aacataatta tttggtaata
     4381 caagttccat ttgttttctc ctccttagtt gaaattgttt catttgtttt acaaatagga
     4441 tgaacttaaa ctatcttttt attactcagt aataatttcc gagatttcat tttatgatac
     4501 tctctattca tacagaaatc aaaattttgc cttaaccaac ttgtataata gaaaaaatct
     4561 aattgattta ttatgatgag ctgtattcta attttatcaa ccttttcttg ccagttgtta
     4621 ttgttactaa tagaaatctc atacagcagt aactcgacaa gacctgtaca cagaagggtg
     4681 ttatgagaat cttcaatttt actcagaata tcctcaaaga gttcactatc cgttaaaaag
     4741 gtggattggt tcatcgcatc atacagctga agagacatta agtcagaata actgagatct
     4801 gatttttgta ttttatcctt taacgtattt gtcaaatcac tttcaaacga atcttctttt
     4861 tcccatttat tttgattgaa aagaaattcc gtcttattaa aaacgagatg attgatatcc
     4921 attatattcc aaaaaaatat tgtagtaagc ataatgatga caaaaggaat ttttaaaata
     4981 aatactagga taatagcaat ttcaagaata aaactccata taatcctaga tcttaaatca
     5041 tcaggcgaca aacttttacg atggaatgaa aaatagggcg agaacctcac atttactttc
     5101 ttcctgccta taaaaataaa aggaaaaatc gtaataagag cttctttctt gtacaaatct
     5161 ttcaatgcgt atagtatgtc taaaactatt tttgataaaa tcaaactaca gaaagcaaga
     5221 ctcatactaa tcacaaaatc aaggggagat tctagattca atagtaagtt attcactagg
     5281 acatgcaact ctagccacaa gacaaaaaga gggagcatta ataaaaaaat gattagttta
     5341 cgtatcataa ttttacagtg tccttatcat tttcttaatt ttggataaat tatcattgct
     5401 atgattaaaa tcaaaaaaac gacattcatc caaataatca acttttttat ttcttcgcta
     5461 acaaaatcat aggctaaaaa agttatggat gatataaata gacatacaaa aaaaataata
     5521 acaaaaattt tttccatttt aatacccata tctagttacc acaaggcgtt taaatttggg
     5581 tctctcctat ttacatcatt gttggcccag attgttgtaa tagcatcgcc aattgacatc
     5641 caagctgcaa atccattaat agcagacagt gcaaatcctg ccactctatt tgcaactcgt
     5701 accccaacat atcttgcagc tgctccagca attgcgcttg taactcgccc caaaccataa
     5761 ttacgaatat aatttctaac tagactgatt gctcctccac ctaaaacacc attaaaagct
     5821 atattaatgg ctgttgcaac aggccatctc agaatagaaa atcccccatc aagatacatc
     5881 atctcttctt gctcaagagc aacataatta tttggtaata cgagttccat ttattttctc
     5941 cttttttatt aagcatagtt aggatagttt cctaacaagt gatagacgac tgtgttttta
     6001 tcacttagct acctagataa gatatccttt ctctacctta tttgttttta taggttacct
     6061 aaggtttaaa atcaattatt gtttgaaact taacagttct aaaccactag caataaatga
     6121 ttgcgaactc actaatacta tttcaaaatt tatttttttt gacttagtaa cgcaattcca
     6181 attagcaata cacctaatat aaataaaagt atttcccaaa atttattctc agttttaata
     6241 agtggaataa gatacatact gactaatatg caacttgccc ctataatggc aaatattatt
     6301 ctggttttat ctcctaattg aaacatgttt gatccccata tacacttcaa gcaaaagttg
     6361 gatttctgaa atggctaaag ataaagataa tggttgcgag ctatttaaac tatcatcaat
     6421 attctgctcg attaaaacaa agtctggtct tacctctaaa attttattta acattgattc
     6481 atatttattt ttttcattat aatgccgtaa atatagattt aattttataa catccaacat
     6541 accataaagt gatattggat gatttatttt tttaaatcgc ttaacttcta ataaatcaat
     6601 ttgttcacgc acactctctg aaagatatgg cttgattaaa ctgatataag ataaagccac
     6661 gcatggcaac tcagattttg attgcaattt ccaaatttca tgataatcct gaagattaaa
     6721 ctcacaattc ttcttagatt ccagtattgt tagtaccttt gattttaaca gaaataattg
     6781 ctgattctca attctataaa gtttttgtac taatgctatg ataatagaaa atggaataag
     6841 aggcaaaagc aacggtttgt catacacaaa agtaaagaaa aaatagtatg aaattagtgt
     6901 tgtaaagtac aagaagtagt aaaatttaaa cagattctta gttgtttgac tctccttata
     6961 aaacactgct actcctggac taaatcccat tagttggtga aagagaattc gatagtattt
     7021 cctagctcct ataatgatca caaatataaa ataaaaataa attggtctta atttacaaaa
     7081 gattgaggaa actagtaata gcaaagtatg taagcattga gacaaaatat agaataacgg
     7141 tatcgccaat acaaaggtta agatggcatg agagggagtt cctaagatgt ccaattttat
     7201 aaatactggg ctgacacaaa atatcgtgct tataagcagt aaaattattc caatctcccc
     7261 catcaagata gcttatttat cctagacaac gcctactgca acagtataaa taagattcat
     7321 cagccatctt ttctggcaat catatgggta gactaatgat atttctagtt actcaaaaat
     7381 atctagctat actagagtta tttctaatcc ctaggacact tgttaatcca aatgtaacaa
     7441 attttcaccc cttaatagga ctctttctgg aaaaaatata aggtctatct ttataaaaaa
     7501 atctatcata ttgggatggc acgcatctgg aatttaaaca agctataaat tcatttataa
     7561 ctactatttg tttagaggca acagcatctt gtataccgcc ctcgaaagaa ccatcttgta
     7621 attccgaaat atttttgttt aaatattgtt ttgacaaatc tcttaatgct tcattatcgt
     7681 aaatgattcc caaaaatcca accttatata gtaaataatt taaacttaca aagtaattga
     7741 atcccatagt atatttttct ttataaagca aaggtaaaac tttataaaaa atatctaagt
     7801 caacctcact ctgattctga agcaagtagg agtcaagcaa attttcaaaa atagctaaca
     7861 atatgattgg tgtaaagttt ttgtattcac atgtcaagta ttctgagtat cgtgcagatg
     7921 atatttcttt tatataactt tttgaaagca agattttttc aaattcatca tctattatta
     7981 atcttctatt tccaatccaa gcggtattac cacccaaata agattgtaca aatagcaata
     8041 tataagaaaa catgaacgta aatactgaaa aaggtagaat tctatgcgta aaaaaataga
     8101 cgataatggt agccaggagt aaagatatct ctcgtgacaa tcgaattctt ttcagcatct
     8161 tttttaacag tccgtaaggt tgtccttggc aatattcttg aactaaatta atcggaatga
     8221 catctctcac catttctgga aagtagagta agtttatagg ttgaaatctc cagctcccat
     8281 cataagtaaa tggatataga accaaatact taaaagattt ttttcttata aacttaatta
     8341 tcacaatatg aatgactgtt gcaatgaagt atattaaata taaaagtaaa accgccatca
     8401 atatacttac aaaaatcccc ttggaatcaa tcaatggaaa ataaaatatt gcaactagaa
     8461 gcgaataaag tcccgctaat aaatatttct gatcatcttt cattcaaaac accatattat
     8521 ttactaagaa tgcatcaata caatagagca actctgtaag tcaatatttg ataaagcaaa
     8581 gctttaaccc cttccccaga cgttagcttt tcttcaaccc actacagttg acaaggagcc
     8641 caaattattg ataaaaactt tagtcatcat cgtctctata aaatattttc tatacactct
     8701 tgataatacc aaaattaatg ccaatatcat accaagagct ataataatag aatttattag
     8761 atttatttta gtatatccaa tcactagtcc aataattgga ctagcagaca tgcttagata
     8821 taataaaaat aacaaaaaat gaatttcacc aattcctgca aaaaaatgtt tcatagctat
     8881 agttttacgc ccataaatac ccatcaaatt taccgtctac gatatctaaa ccatatgcaa
     8941 tggctcctcc taatgagaag acttcagcaa cagtagccgc aatattaaga gcattagtaa
     9001 tagttgccat actaactcca ccaatatatc ttgttataac acttagttac ctagataaga
     9061 tatcctttag cttgcttcca aaatttaagt ctgcacctat aatatgagtt catattaata
     9121 ctgctaaatc ctatctatag taatgtcaaa cacccaaata aagtcatctc tccaattcat
     9181 tcaagaaatg aagaaaggca aaaaatcttt aaaataagaa aaatgcatat tatcaggtgt
     9241 tcaaaaatat tgatgatata cgttatatag atagaaagat ttactcaatc tcattttcaa
     9301 attgagtttt ttcccagcct cgtttttaat ttatatcttc aatagaatct aatgacctag
     9361 ttgatatgtt atatggaata atattattta atctgtaatt tttttaaaaa acttaatagt
     9421 aaatttgctc cactgatttc tatcaatatt tcaattggta aaaaatagta attccaaata
     9481 aaatgagaaa tcagcaatga tagaaaaata acaatatcaa ttttcctgtt gttgacatac
     9541 tctgtaattt tatgatacag taatgcaaca ataactgaaa ttaaaacaat caacataaga
     9601 ttattaacct attctcaatt gattatcacg tcgcccatcc cagccatcaa taatattggt
     9661 aaaaatccaa tcagctccag caccaattcc agcagatgca atacttctaa taacagtatt
     9721 tgcaaaagca tttccaatat gaattcctaa tactcctaaa cctttaacaa tcccagctac
     9781 cagtgcggag cgtaatccat aagatgcaag aactagttga aggcctccac ctcctgctgc
     9841 tgctaatgct gcatatgctg caccagtaat ggctcctgta attgcccacc tgggtatata
     9901 tatagccccc ccatcaaggt acatcatctc ttcttcatca atcacaacat aattatttgg
     9961 taatacaagt tccatttatt ttctcctttt ttattaagca tgcttaggat ggtttcctaa
    10021 caagtgatcg caggctttgt ttagttacct aaattagact tccttccttt atcttatttt
    10081 aaatatttaa aaccagttac tgcttgaagc ttaacagttt acttaattca aataacagct
    10141 aatcactgat tccctgattt tatcaaatat actaataaca acaattgtga tacgatcatc
    10201 attataagaa caacatttaa cgaatcaaag tttttccgag ataataataa agcaacagca
    10261 agcagtatta ttactaaaga ttgaataact actattactc ttaacatttt atcctccact
    10321 aacaactcaa gctcccttac attatatcga ccagccccat ggaaagatta tagctagact
    10381 aatcaatgat ataatacata ctagaataca aaatattttt ttattcatac tttttctcct
    10441 atctttattt tctacctaca tagtacctct tattaagctc atttcaaaat tacgttaact
    10501 tttttcacaa atttatttcg actttctttt ttacttttta cattgctatg atacaatatt
    10561 tttaacaaga ttttattatt tgttaacttt tttcacagaa aggagaaaat catgcgttat
    10621 gatttcggaa aggtctataa agaaatacgt gagtcaaagg ggctgaccca agaagaggtc
    10681 tgtgggggtg ttctctcaag aaccagctta tcaaaaatcg aaagtggcaa gacaacccca
    10741 aaatatgaaa atatggaatt tcttctccgt caaatcaata tgagttttga agagtttgaa
    10801 tatatctgtc aactttatca accaagtcaa cgcacagaga ttatgcaaac ctatctcaat
    10861 atgcgttcca ttatcgggac cagcgatctt gtcaatttat ttcaaaaatg ccaagactac
    10921 ctcaagatcc accacgatct ccctatagaa gaaatcagag atatgcttga agttgtcatt
    10981 tatatccgtc aacacggggc aggggaacta tcagatcacg cagaacaggt tgtcaaaaaa
    11041 ctttggagaa aaattgaaaa acaagataca tggtatgaga gtgatctaaa aatcctcaat
    11101 accattcttt tcagttttcc cattgaatac ctccatctca tcactggaaa aatattgcaa
    11161 cgcctagaag tctataaaaa ctatcaacat ttatatgact tgcgaatagc aatcctgctc
    11221 aacctttcca cactctatct atacaatcaa gataaaaaca tgtgtaagca aatctgctac
    11281 actttactgg aggacgccaa gaataagaaa agctacgata ggctggctat ctgctatgtc
    11341 cgcattggga tttgtacaga cgattctaaa cttatccaaa aaggtttctc actcctagag
    11401 ctgaccgagg aaacttctat gctgtctcat ctcaaaaaag aagtagagat ctattaccaa
    11461 gcgaaggaaa gataaaaaag ccgagggagc tcctcgacct tttcatagaa tcgccgaacg
    11521 atttaacgag aaagtatgac ttttacgttt atcccaactc aattatgaca tttttttcaa
    11581 aagtcaatat atctcacttt ttcaacgaca agaaagaggc tgccaatcga ccaacctctt
    11641 attctgaacc catcactcca tcacttttta gcttcattcg ttttcttagc gactgcaatc
    11701 tggtattcga cttggtcaaa ccccttaccg gtacaaccat gagcaattgt agtcgctcct
    11761 atctgatgcg ctatttcaac caatttttta gaaatcagag ggcggctcaa ggcagatacc
    11821 aagggatact tttgttcata ataggcatgt gactaatgag ccactagcac ataatctgta
    11881 gcaaattcgt ccttaacatc aatgacataa gattctactg cccaaacctt aagagcctta
    11941 tcatggatga aatctaagtc tttcccttca cccacatcca tacaaactga aacaacatca
    12001 tagtctttct ttaaccaggt aatagcaact gatgtgtcca aaccgccaga ataggccaaa
    12061 attacttttt ctttactcat gttcttttcc ttctttctat ttttcaatgg atgctttaaa
    12121 ggcatcctca atgagtttgt ctaattcccc agactccttc aacttttgaa tggttttatc
    12181 gactgcctct ttcaattcct tgctatcttt tttcatggct accgcatagg aatcatcttg
    12241 ctctttttca aaattgaggt ctgcgattgc taaatcagga ttattttcca caaatccctt
    12301 ggcaacgggt tcttcaaaaa taacggcatc cacttgccct gattttaaat ctgtgattaa
    12361 attcccattt ttaggcagag atacgaggga agaattttgt agcaaatctt tcgccatcgt
    12421 ctcttgaatc gaacctttct gcgctccgac ctttttctgc gccaaatcgt tgacagactg
    12481 ataagtggct aaatcagatt ttttgacaat gagtttattt tttgcagtat agtagggagt
    12541 tgaaaaatca aacaccttgc tccgttcatc tgtcttagaa acacctgata tggcaaggtc
    12601 agcttttcct gattgaacgc tagccagtac attgtcaaaa ctcataggag atagttccaa
    12661 ttcgacacct agttctgttg cgatagcctt ggctaattcg atatctgaac ccacaatctg
    12721 atttttccca tcaaccactt tttgatattc aaatggagca aaatctggat tgagggctac
    12781 aaccaatttt cctttggact tgatggcttc aattccagcc gattgattgt tactacaagc
    12841 aaatagtagg gggagcatca ctaaaccaaa catcgtcatc aacaccttct tcatcttatt
    12901 cataacaaag cctcctttat gtttattctt ttttattgta taaacaatac tcctatactc
    12961 atcctttgtc aagcctaaat tgaaaaaatt ttcaatttga aacaaaaaaa acctagaaat
    13021 actacataaa atgtcattcc taggcgtatt tatgctattt ttctctggaa aacatgagta
    13081 ttcagccagt caaaaggagc tgaatgaact cattttccct cgcccaattc aatgacacga
    13141 tgacattgtt gggctacata agcatcgtgg gtcacaataa tgactgtttt cccttctcga
    13201 ttcatctcta agagaaactt caagaccaaa tctctatttt caggatccag cgaacctgta
    13261 ggttcatcgg ctaaaatcag ctggctgggt tttaagatgg ctctagcaac tgcaattcgt
    13321 tgttgttcgc ccccagacaa ctcggagacc ctttgatgca aagtagctga caaacctact
    13381 ctctctaaaa tctcttccac ctttttgagc ttgtctttct taggcaattt cacatatttc
    13441 agcgccagca tgagattgta ctcgaccgtt tcatcatcaa tcagggcaaa attttgaaac
    13501 agataagaga tatgttcacg gattattgtt tgcgacttag cagaattaac cgctagattt
    13561 gtctgaccaa aaatctcata ccgtccgcta taatcaccat ctatcaaacc caataaattt
    13621 aacaaggtcg acttcccact accactctta ccaacaatag ctaccaaatc cccctgatca
    13681 atcctgagag ataagttatc caaaatcact tttcccccaa tggttttggt aatatttttc
    13741 aactcaatca taagatgccc cctttcaata actctactag acttcttttc tccatcctag
    13801 aagctaagcc tagcacaaat agtatatcca gacatgtaaa acctgcaaac agtagaagtg
    13861 gtaagaacgc atgggcaaag aaaatcaaga ctagaagagg gaaactatag cccagcaaga
    13921 gcagaacgag gagaggacgg tagcgatcga ccagtttcca ccccataaac ttcttggtaa
    13981 tgatatccct gcgcttcaat aagaaagttg ttactagtaa gaagtaggaa atcatcatgc
    14041 taaggagacc aaacaaagca aagagtaggt taaaattccg aacagcatct ctataagaat
    14101 ccactttctc ttgttgaatg gcttgaatag atgaaaattt taaataattt ccatctgaca
    14161 atttctcaac taactctgta atctcttttt gatgttgaac cgtattttca attttaatcg
    14221 gattatttaa gccagttgtt gacagggagg ctttctcatc ccacatcata tcagaatcat
    14281 tgaccaagct aataattgga ttggagagat tttcctttcg cttatcacta tatgggaaaa
    14341 atgaccaatc tccttcataa taggcaatct cgacatccat ctcctctatc gttcgttttt
    14401 gctgctcttc atacttcatc gaatgaaagg caattaactt ccccaagagc tgatttttat
    14461 cttcttcacc tttcgtactt gctggcatca aaataacttt tttaataccg gtatctggta
    14521 gcttgaatcc cttgctcttt agaaaattgc gattggcata gtaaacatcc accgtatctg
    14581 ttaactgata ttgctgaatc tgttctgatt ggacaaaatt ttttacagga agactgctac
    14641 tctgcacata gcccgcctgc gttttttcta ccaaatcctg ataaaatcga tagaaataat
    14701 ctgtagattt ccctgaccct gctagctctt cttgccacag attatcattg agtttgaagg
    14761 tttctaaggt caggtaatta ccttgactta cccactgttg ctgataagca agttctttgt
    14821 tttcttgttc taaacttctg cccaccccaa tcagtaaggc cgtcagtaaa atagttgtcc
    14881 ctattttcat cacataattg aagataagac caaatttgaa agatgaaaaa cctttcagca
    14941 gagagctgat tgtcattttt tggattaaga ggtaagtcaa ccaactgata aagagataaa
    15001 gctgcaacag caaaaaatga gacaaccaca gcataggaaa caaatctttt ggcttataat
    15061 caagcaagaa aaacacgcct agattgatca caagagcccc acctaggagg aggtaaaggt
    15121 tgccttttac aacatcagct aaaacagccc tatcttgaaa accaagtaat ttttgtaccc
    15181 caactctttt catctccatc atcggttgat atactgtcac taacacaaga agcaaaatag
    15241 ccaagacaaa aacaatggca gataaaagca aatctcgatt tatgacttcc actgcacttt
    15301 tgtaggtcgg ctctagcacg gtagcctggt ctatcttgaa aaaatcgctc catttctgta
    15361 caatcctatc cttgtccatc tcttgtgtag aagttatcgt atagcgacca tttaaactac
    15421 gagatgtatc cttgatatag gtttgaaaag tcataagctg aataggtttg gcttttagaa
    15481 aggtcggaat cgtaccaagt ttattggaaa tttctttatt actatagact ccttcaccat
    15541 ctgtggtaaa atcaagagaa gaaatcccaa actcttggta ggggaaggta tctttatcaa
    15601 aaacaccaga cttgaccacc tcatcaccac tgtctgtttt gatgatggag actttatact
    15661 cctttgatac atcctcaaaa aatcgaagaa cagacgctgc aggttcgtta atatctttca
    15721 aatacaaatc caaagaatct acagtctttc ccatttcttg aatccgaacc acttctcgtg
    15781 tatagtttac attaaaaaca aaaaaagtgg tacacagaag caggagtaac atacagaaat
    15841 tactgatttt tttcataaaa gtgcctccac tacagttttc cctctccaaa taggagaggg
    15901 aagaatttta ctcaaatcca tagaaatatt ccattactgt tggcggaatc ttggtgaggg
    15961 aagctctagc ccatgcctca ggttttgcat aatccttaga ggttctaccc ccatgtctaa
    16021 cagttgctgt atgatatcga gtagaatgta agtaatcaga atatccaaaa gttcctgtcc
    16081 aacctactcc atagttccat tgaccaccct caacccatac tgctaaagca tttgtagtag
    16141 caagtatacc acataccatt aaagatgcaa caccaatttt aactaatttt ctcatgattt
    16201 atttctccta ttatcgagag ctgttccgta aaaacagcta tagtaattta tcaacaagta
    16261 tcgtagtcca ttggactcac cttccttcta tctcatttca ttttttaaca acgaacttac
    16321 tcttaaccgg gagaatggtg cgcttctgta tcaggtcctt gaacaaccag agtagtatta
    16381 agcacactct aactattact caagaatcag tccaataaac aatatggata gcgctttcaa
    16441 atttttaaac tcctatcccg tccttttatc tatataataa gcataagcga aaatataata
    16501 actgtcaagt atctgaagtg aattttataa aaaaattaca agccaaattt gtaaagttta
    16561 cactaagccg ctagggcaat cgtctatcag aatgtccgtt tatttgtcaa taatccgaga
    16621 aaatcttgca acgcttagaa gtctataaaa actatcaaca tttatatgac ttgcgaatag
    16681 caatcctgct aaacctttcc acactctatc tatacaatca agataaaaac atgtgtaagc
    16741 aaatctgcta cactttactg gaggacgcca agaataagaa aagctacgat aggcttgcta
    16801 tctgctatgt ccgtattggg atttgtacag ataatgctaa acttatccaa aaaggtttct
    16861 cacttctgga gctgaccgag gaaacttcta tgctgtctca tctcaaaaaa gaagtagaga
    16921 cccattatca accaaagaaa ttataaaaaa agtcgaggga gctcctcgac cttttacata
    16981 ttatttgttc gttagttctt aataccagcc attgttaagc cagaagtttt tagcagcagt
    17041 ccatgaaccg taacgtcctg caacgtaggc atctgctaca cgttcttggt tttcagctga
    17101 gtagtcaccg ttcaggtatg aatctgttaa ttggtaacgt ccgatataac gtccatttgt
    17161 agctgtatag ctaccacctg attctttttg agcgatccat tctttggctt ctgcttcaga
    17221 tccgcttaca gttgaaacaa ctgtttcact tactactgga gctgaaacag tttcatcttg
    17281 agcggctggt gccgcataag tagctggcgc tggtgttgca acaggcgcta cagggccatc
    17341 gataaccaac tcttgatcaa cataaatcaa atgaatgtta tcaatgtggt tgttttctgc
    17401 caatttttca actgttgtgt tgtgagtttc agcgatttct gaaagtgtat caccttcttt
    17461 aacagtgtaa gttgatgatt cttgagcaga tacaaatgat ggagcaaata ctgcaaacaa
    17521 ggcagctact cctgcaagag ttgctttaat ctttttagtt attgatttca tattcgaaaa
    17581 ttctccttct ttctatagtt ctatcatacc ctttaaatat taccgtttct tgacactttt
    17641 atgtagaaat attacaaaat tattttttat ttccctaaat aaggtgtttt ttgtcataaa
    17701 agatactatt tttatgctat ttgaggtatt agaaaggttt tcatccacaa ttaaagccaa
    17761 gcccctcatt ctttgatata atagagataa gaatttttat aaggggaaac tgatgaaatc
    17821 acttcgtttt caatctgtct ttgatatcat cggaccagtt atgattggcc catctagtag
    17881 ccataccgct ggtgctgttc gtattgggaa gattgtctct tccatttttg atgatactcc
    17941 gacagaagtt gaattccaac tttttaactc atttgccaag acctatcgtg gtcacggaac
    18001 agacctagcc cttgttgcag gtattttagg aatggataca gatgatcctg aaattccaaa
    18061 tagtctggaa attgcccaca agcgtggtat caagattgtc tggaccattc agaaagacag
    18121 caatgcccct caccctaaca ccactaaaat tactgttaaa aatgcccaca agaccatcag
    18181 cgtgactggt atttctatcg gtggaggaaa tattcaggta accgaactca atggttttgc
    18241 cgtctctctc aatatgaata caccgactat catcatcgtt catcaagata ttccaggtat
    18301 gattgccctt gttacagagg cgctttcccg ctatggtatc aatatcgccc agatgaatgt
    18361 cactcgtgaa aaagctggtg aaaaagccat tatgattatc gaagttgaca gtcgcaactg
    18421 tgatgaggct atcgaagaaa ttcgaaaaat ccctcatctc cacaatgtca atttctttaa
    18481 ataggaggaa gcatgtttta ttctatcaaa gaattggtcg agcaagcaga tctagacttt
    18541 caaggaaatg tcgcagaact catgattaca acagagtttg aattgaccgg tcgcgaacgt
    18601 gaagaagtct tccttctcat ggaacgcaat ctggaagtta tgaaagcctc tgtccaactt
    18661 ggcctcaatg aaaataaatc tcgtagtggc ctgacaggtg gagatgctgc caaattggat
    18721 cactacatcg aaaacggaaa aactctgtca gattatacga ttctctcggc tgcccgaaat
    18781 gccatcgcag tcaatgaaca caatgccaaa atgggcttgg tctgtgccac tccaaccgct
    18841 ggaagtgctg gctgtctgcc atccgttctc actgctgcta ttgaaaaatt agacctcagc
    18901 cacgagcaac aattggattt cctctttgct gctggtgcct ttggactagt catcgcaaac
    18961 aatgcctcca tctcaggtgc tgagggtggg tgtcaagctg aagttggttc agcctctgct
    19021 atgagtgctg ccgccttgac tctggctgca ggtggaacac cttatcaggc cagtcaagct
    19081 attgcctttg tcattaaaaa tatgctaggc ctcatctgtg accctgttgc aggtttggtc
    19141 gaagttccct gtgtcaaacg taatgccatg ggagctagct ttgctttcat cgcagcagac
    19201 atggccttgg caggtatcga atctaaaatc cctgtggatg aagtgatcga tgccatgtac
    19261 caagtaggag caagcatgcc aactgccttt cgtgaaacag ctgaaggtgg actcgctacc
    19321 acccctactg gtcgtcgcct ccaaaaagaa attttcggag aataagctta tcaaatagga
    19381 gaaaccatga cctctatcac agcgattttt ttcgatttgg atggaaccct cgttgatagt
    19441 tctatcggga ttcacaatgc ctttacctat acctttaaag agctgggggt gcctagccct
    19501 gatgccaaaa ctattcgtgg ttttatggga ccacctctcg aaagtagttt tgcgacctgc
    19561 ctgtccaaag accaaatttc tgaagccgtg cagatatatc gttcttacta taaggcaaaa
    19621 ggcatctatg aagctcaact ctttcctcag attatagact tgcttgagga gttatcgagc
    19681 agttatccac tctacatcac cacgacaaag gatacatcta ctgctcaaga catggcaaaa
    19741 aacttggaaa tccatcattt ctttgatggc atttatggtt ctagccctga agcaccccat
    19801 aaggcagatg tcattcacca agccttgcag acacatcaac tagcaccaga acaagccatc
    19861 atcatcggag ataccaagtt tgatatgctg ggagctcgag aaacaggtat tcagaaattg
    19921 gccatcactt ggggatttgg agagcaagca gatctactaa actatcaacc tgattatatc
    19981 gctcacaaac ccttagaagt tttggcgtat tttcaatagc atagactggg taacaattcc
    20041 atttcagaag aaaatgaagt aatactcaat gaaaatcaaa gagcaaacta ggaaactagc
    20101 tgcgggctgc tctaaacact gttttgaggt tgcagataga actgacgaag tcagctctaa
    20161 acactgtttt
//
LOCUS       DAVAGB010000038        19508 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVAGB010000038 DAVAGB010000000
VERSION     DAVAGB010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19508
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.038"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            120..929
                     /locus_tag="VQO19_001545"
     CDS             120..929
                     /locus_tag="VQO19_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET1349780.1"
                     /translation="MLLQKELIPMIEANLPNMAYAEKDIAKFFLKQQPLNDYSSKALC
                     EYLNVSKATLTRFAKKCGFKGFRQFIFKYQEMIHEKEKLALYTEATEKVLSDYEEMLR
                     KTYTVLDEVQLERIAEMIETAERVYLYGKGSSVLALQEMKMRFMRLGVIGEVLSDEDM
                     ILWSSLLLNENCLVIGASISGQTDIVLEGLQKAADKGAKTVLMTTRKFDEEDCFFDEL
                     LLLASTDHLSYGNRISPQFPILLITDCLFSNYLESPERQYYYNQTIIHKEE"
     gene            934..1635
                     /locus_tag="VQO19_001546"
     CDS             934..1635
                     /locus_tag="VQO19_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET1349781.1"
                     /translation="MSQIWTKEKFISQVQGGVIVSCQALPGEALYNEEFSLMPFMAKA
                     ALEAGAVGIRANSVRDIKAIQKVVDLPIIGIIKRDYPPQEPYITATMKEVDELVECGT
                     TVIAFDATLRPRYDGLVVSEFIKKIKEKYPNQLLMADVSNLDEGLYAFKSGVDFVGTT
                     LSGYTSTSVQSDEPDFELMKKLADFNIPVIAEGKIHYPEQLKKAYSLGVTSVVIGGAI
                     TRPKEIAQRFINVIK"
     gene            1660..2577
                     /locus_tag="VQO19_001547"
     CDS             1660..2577
                     /locus_tag="VQO19_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HET1349782.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQDRVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHIACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAASNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            2605..4146
                     /locus_tag="VQO19_001548"
     CDS             2605..4146
                     /locus_tag="VQO19_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HET1349783.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGSSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGVVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLIANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLATATVFYLIGTGLYVFYQVQNADSAASNIPQDQIFMYFIAYQLPVGITGL
                     ILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDNRRTKIAQFVSLAVGLFSIG
                     VSIVMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDITEIKADSS
                     WEVRH"
     gene            4165..4623
                     /locus_tag="VQO19_001549"
     CDS             4165..4623
                     /locus_tag="VQO19_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET1349784.1"
                     /translation="MIISEQSDFKRYASVNKYFSKVCDFLENTNLTDLVDGKIDIDGE
                     NVFANCMTYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDETVKKLVIKVLNEEK"
     gene            4625..6847
                     /locus_tag="VQO19_001550"
     CDS             4625..6847
                     /locus_tag="VQO19_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HET1349785.1"
                     /translation="MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPKLVQPV
                     APTTPISEVQPTSDNSSEVTVQPRTVETTVKDPSSTAEETPVLEKNNVTLTGGGENVT
                     KELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNNLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPVPLEWPREVGGRDLQISGGATYIDSVIVEKKNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLRKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFENNKKTEYRNGTKVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            6887..7996
                     /locus_tag="VQO19_001551"
     CDS             6887..7996
                     /locus_tag="VQO19_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET1349786.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEFEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            8153..9043
                     /locus_tag="VQO19_001552"
     CDS             8153..9043
                     /locus_tag="VQO19_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET1349787.1"
                     /translation="MKIIGIDIGGTTIKADLYDEFGTSLNHFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYTLNHSIDGVGISTAGVVNANTGEIIYAGYTIPGYIGVNFTAEIEKRF
                     GLYTFVENDVNCAALGELWKGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLRSGDKVAEETFEIFVE
                     NLTKGLLTISYLLNPEILILGGGILDSKDILLPEIQSSLAKNAMDNRFLPKNLVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            9068..9391
                     /locus_tag="VQO19_001553"
     CDS             9068..9391
                     /locus_tag="VQO19_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349788.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELVSIESNLEMKQQNLIDEVNKTIKENDANIQYISSSRRGEFVEKIIGRVV
                     EKYGH"
     gene            9381..11372
                     /locus_tag="VQO19_001554"
     CDS             9381..11372
                     /locus_tag="VQO19_001554"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HET1349789.1"
                     /translation="MAISQMKRISLLFSKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFPTIQIFHTSNSNHGVIEGNDALTYLMNQQQHLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNHQINRVHELERHIQSNNEEIERLIKW
                     EKLEIVPANLEQFSFCKGKVGTIPRTEDNRLYNSLLENNIEVQEIFSNDREYGVVVFY
                     QSSYSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKKYLID
                     LQWQIDYILSIYARQISKNNFLCTPHLVALEGWIEETRILYFIKVMDEHFGHSIYIYE
                     SETLTDNQDEIPIKLTNHSLIEPFELLTEMYALPKYYEKDPTPVLAPFYFTFFGMMVA
                     DLGYGLLLFLGTMLALKIFHLPSATKRFLKFFNILGVAVAIWGGIYGSFFGYELPFHL
                     ISTTSDVMTILVVSVVFGFITVFAGLLASGLQKVRMKKYAEAYNSGFAWCVILLGLLF
                     IAVGMLMPDMRPLFVLGKWVSIFNAVGILIVSIIQTKSLSGIGAGLFNLYNISSYIGD
                     LVSFTRLMALGLSGASIASAFNLIVGLFPGILAKLTIGLVLFILLHAINIFLSLLSGY
                     VHGARLIFVEFFGKFYEGGGKPFQPLKASEKYIKVITKN"
     gene            11388..11864
                     /locus_tag="VQO19_001555"
     CDS             11388..11864
                     /locus_tag="VQO19_001555"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HET1349790.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            11898..12479
                     /locus_tag="VQO19_001556"
     CDS             11898..12479
                     /locus_tag="VQO19_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349791.1"
                     /translation="MSNLENLRESVIEQAHEKGRMKLLDSKKKIDDEFEMQKSLIIKK
                     KEAEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALLEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNYLFSEQPISNESGLLI
                     SIGKIDDNYLYKTLIGSISKEESSSIANQIFIN"
     gene            12544..13551
                     /locus_tag="VQO19_001557"
     CDS             12544..13551
                     /locus_tag="VQO19_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HET1349792.1"
                     /translation="MDTNLFSKINTTISVKENDFITEEKFQKIIQSKDTETLAFILES
                     TPYHLSIDILEDPSQTEISLMTKLVNDYRWAYAESPSDIIVTLFALRYVYHNIKVLLK
                     SKAAIKKDFSKLLIPIGIFDIESLKHLVSSLHSDTLPDFMVREVESIWNEYETFNNIR
                     VLDVGADLAYFKHLKLLSNELDEVLSQVIVEMIDFYNIITVKRGLSQNKSHGDILQLL
                     SDEGSISAKEFIYIVENQEIFVWFNKINPSLDSIFSTYELKMQDATISSSELEFLCDL
                     LLYKTLDQGRYNVEGPLVLARYLLGCEFEVKNLRMIISALQNTIPFESIKERIRPHYG
                     S"
     gene            13541..13861
                     /locus_tag="VQO19_001558"
     CDS             13541..13861
                     /locus_tag="VQO19_001558"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HET1349793.1"
                     /translation="MEANKYKIGIIGSRDIILPFSMIGFDIFPAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            13924..15699
                     /locus_tag="VQO19_001559"
     CDS             13924..15699
                     /locus_tag="VQO19_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HET1349794.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTISIGQKVSTGDILGTVKETEVVNHKIMVPYGISGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQALGLPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGTYIDDKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSENERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIIEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIQLILETGGL"
     gene            15700..17085
                     /locus_tag="VQO19_001560"
     CDS             15700..17085
                     /locus_tag="VQO19_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HET1349795.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLPSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVKFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            17108..17719
                     /locus_tag="VQO19_001561"
     CDS             17108..17719
                     /locus_tag="VQO19_001561"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HET1349796.1"
                     /translation="MVRLNVKPTRMELNNLKERLKTAERGHKLLKDKRDELMRRFISL
                     IRENNQLRKEVESYLIDNLKAFAVAKSLKNSLMVEELFSIPSKEIELFVEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIDKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
     gene            17795..17998
                     /locus_tag="VQO19_001562"
     CDS             17795..17998
                     /locus_tag="VQO19_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1349797.1"
                     /translation="MTVSGYLFQNFGLLDNENVSTDLDLGLISRKCNFKEKDKLKKDV
                     LARVGLTHIHLEQKIYELSGGEA"
     gene            18095..18205
                     /locus_tag="VQO19_001563"
     CDS             18095..18205
                     /locus_tag="VQO19_001563"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1349798.1"
                     /translation="MKLLLDMKNENRLIIIATHNPDIWNQADEVINLNQL"
     gene            complement(18305..19508)
                     /locus_tag="VQO19_001564"
                     /pseudo
     CDS             complement(18305..19508)
                     /locus_tag="VQO19_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element ISSpn4 family transposase"
BASE COUNT         6512 a         2874 c         3837 g         6285 t
ORIGIN      
        1 gttctgttat gaaacgaaag aaattggaaa ctagtttcta atttatgaaa aatattgaaa
       61 aaaaaaaaaa aagtgttaaa ataaagaatg taaacgttta cttcaactaa ggagctcata
      121 tgttactgca aaaagaacta attccaatga tagaagctaa cttaccaaat atggcatatg
      181 ctgaaaaaga cattgctaaa ttcttcttaa aacagcaacc tctgaatgat tattcatcta
      241 aagcattgtg cgaatacctt aatgtatcca aagcaacatt gactcgattt gcgaaaaaat
      301 gtggttttaa aggttttaga caattcattt tcaaatacca agagatgatt catgagaaag
      361 aaaagttggc attatataca gaggcaacag aaaaagtttt atccgactat gaggaaatgt
      421 tgagaaaaac ttacacggtt cttgatgaag ttcaacttga gcgtattgct gagatgatag
      481 aaactgctga gcgtgtatat ctctacggta aaggaagttc tgttcttgct ttacaagaaa
      541 tgaagatgag atttatgcgt ctcggagtga ttggtgaagt attatcagac gaggatatga
      601 ttttgtggag tagcttacta cttaatgaaa attgccttgt cattggagca tccatttcag
      661 gtcaaactga tattgtacta gaaggtctac aaaaagctgc agataaaggc gctaaaacag
      721 ttttaatgac tacaagaaaa tttgacgaag aagattgttt ctttgatgaa ctattgttat
      781 tagcttcgac cgatcatctc tcgtatggca atcgcatatc acctcagttt ccaatacttt
      841 taattacaga ctgcttattc tctaattatc tggaaagtcc agagagacaa tattattaca
      901 atcaaactat tatccataag gaggaataat aaaatgagcc aaatttggac taaagaaaaa
      961 tttataagcc aagttcaagg tggagtcatt gtttcttgtc aagctttacc tggtgaagcc
     1021 ctttataatg aagaatttag cttgatgcct tttatggcta aagcagcttt agaggcagga
     1081 gcagtgggca ttcgcgcaaa ttctgtgcgt gatattaaag caattcagaa agtagtagat
     1141 ttaccaataa ttggaattat caaaagggat tatccacctc aagaaccata tattactgct
     1201 acgatgaaag aagtagatga acttgtagaa tgcggaacaa cagtcattgc atttgatgca
     1261 actttaagac caagatatga tggcttagtt gtcagtgaat ttatcaaaaa aataaaagaa
     1321 aaatatccga atcaattgct gatggcggat gtaagtaatt tagatgaagg tctctatgca
     1381 tttaaatcag gcgttgattt tgttggtaca acattatcag gttacacaag tacaagtgta
     1441 caatcagatg agcctgattt tgaactaatg aaaaaattgg ctgattttaa tattccggta
     1501 attgccgaag gaaaaattca ttatccagaa caattaaaaa aagcttatag tttaggtgtt
     1561 accagtgtag tcattggtgg agcgattaca cgtccaaaag aaattgctca gcgatttatt
     1621 aatgtcatca aataaaaaac aatataaagg agaaatctga tgaaagattt aactaaatac
     1681 aaaggcgtta tccctgcatt ttatgcttgc tatgatgaaa atggtgaaat tagccaagat
     1741 cgtgtaaaat ctctggtaca atatttcatt gacaaaggtg taaaaggtat ctatgtaaat
     1801 ggttcttcag gtgaatgtat ttaccaaagt gtagaagatc gtaaacaaat tattgaagct
     1861 gttatggaag ttgctaaagg taaattaaca gttatcaacc atattgcatg taataacacg
     1921 aaagatagta tcgaattggc aaaacattca gaaagtgttg gagtcgatgc tattgcagct
     1981 atcccaccta tttatttcaa attgccagag tattcaatcg cagcatattg gaatgcaatg
     2041 agtgaagctg cgtcaaatac agattttatt atctataata ttccacaatt ggcaggggtt
     2101 gcgttgactg gtagtttgta tgcaacaatg cgtcaaaatc ctcgtgtgat tggagttaaa
     2161 aattcttcta tgcctgtaca agatattcaa atgtttgtag ctgcaggtgg agaagattac
     2221 attgtattca atggtccaga tgaacaatat cttggtggtc gcttgatggg agcagaagct
     2281 ggtattggtg gtacttatgg cgttatgcca gatttgttct tgaaattgga aagtttgatt
     2341 caagaacgag atttagatac agctaaaaaa cttcaatatg ctatcaatga agttatctat
     2401 aagatgatat caggtaaggc aaatatgtat gctgtagcaa aagaagtttt gcgtctaaat
     2461 gaaaaacttg atttaggttc tgttcgtcaa cctttagaag cattggcaga aggtgacttg
     2521 gaagttgcaa aacaagcagc agaacttatt caacaagcac gaaaagaatt tttataataa
     2581 ataaaatcaa tatggagata tgttatgggc acaacaggat ttacaataat tgacttaatt
     2641 atcttgattg tttatttact tgcggtgttg gttgcaggta tctatttctc taaaaaagag
     2701 atgaaaggaa aagagttctt taaaggagat ggttcggttc cttggtatgt tacttcggta
     2761 tccatttttg ccacaatgct cagtccgatt tccttcttgg gactcgctgg tagctcttat
     2821 gcaggtagct ggattttatg gtttgctcaa ttagggatgg tagtagctat tccactgaca
     2881 attcgtttta tcttacctat ctttgcacgg atagacatcg atacggcata tgattacttg
     2941 gataaacgtt ttaattctaa agcacttcgt attatttcag cactcttgtt tattatttat
     3001 caattgggac gtatgtctat cattatgtac ctcccatcag ctggtttatc agtattgaca
     3061 ggaattgaca tcaatatttt gattattttg atgggtgtag ttgcaattgt ttattcttat
     3121 actggtggtc taaaatccgt attatggaca gactttattc aaggtgtgat tctgattagt
     3181 ggtgtcgttt tagctttatt tgtactgatt gctaatatta aaggtggctt tggtgcagta
     3241 gcagaaacat tagcaaacgg gaaattcctt gctgcaaatg aaaaactttt cgatcctaac
     3301 ttgctttcaa actccatctt tttaattgtg atgggttcag gctttacaat cttgtcttcc
     3361 tatgcttcat ctcaagattt ggttcaacgt tttactacaa cacaaaatat taagaaactt
     3421 aataagatgt tgttcacaaa cggtgttttg tcacttgcaa ctgcaacagt cttttacttg
     3481 attggtacag gcttgtacgt attctatcaa gtacaaaatg cagatagtgc agctagcaat
     3541 atccctcaag accaaatctt tatgtacttt attgcatacc agttaccagt aggtatcaca
     3601 ggtttgatct tggcagcgat ttatgcagca tctcaatcaa ctatttcaac aggtttgaac
     3661 tctgttgcaa cttcatggac attggatatt caagatgtca tttctaaaaa tatgtcagac
     3721 aatcgtcgta cgaaaattgc acaattcgta tctctagcag taggtttatt ctcaattggt
     3781 gtttccattg tcatggctca ctcagatatt aaatctgcat acgaatggtt caatagtttc
     3841 atgggacttg tacttggtct acttggtggt gtatttattc ttggatttgt ttctaaaaaa
     3901 gcaaataaac aaggtgctta tgcagcgctg attgtatcaa ccatcgtcat ggtatttatt
     3961 aaatacttcc ttcctccaac agctgttagc tactgggcat attcattgat ttcaatctct
     4021 gtatcagtag tttcaggtta tattgtatct gttcttactg gaaataaagt atctgcacct
     4081 aaatatacaa cgattcatga tattacagaa attaaagcgg attcaagttg ggaagttcgt
     4141 cactaataga aaagagaaaa taatatgatt atttctgaac aatctgattt taaacgatat
     4201 gcttctgtca ataaatattt ttcaaaagtc tgtgattttt tagaaaatac aaatttgaca
     4261 gatttagttg atggaaaaat tgatattgac ggggaaaatg tttttgcaaa ttgtatgact
     4321 tatctagctg atggagttcc aggagatatt tttgaaactc ataagaaata tttagatatt
     4381 catattgttg ttgaaaatac tgaaaaaatg gcagtaactt ccccagttcg tgcccagtca
     4441 cgtgtacctt ttagcgaaga gaaggatatt gctttttacg atagcaaaga ctatcaaatt
     4501 gttgaattgc ttccagggaa tatgttggtg acttttgaag aagatcttca ccaaccaaag
     4561 attcattgca atgatgaaac tgttaaaaaa cttgttatca aagttttaaa cgaggaaaaa
     4621 taaaatgaaa aaaaatatta aacaatatgt aaccttaggt actgtagtgg tattatcagc
     4681 atttgttgct aactcagttg cagctcagga gactgaaact tctgaagtat caacaccaaa
     4741 gttggtgcaa cctgttgcac caacgactcc gatttcggaa gtacaaccta catcggataa
     4801 ctcttcggaa gttactgtac aacctcgaac agttgaaact actgttaagg atccatcttc
     4861 tacagcggaa gaaactcctg tcttagaaaa aaataatgtt actttaacag ggggcggaga
     4921 aaatgttact aaagagttaa aggataaatt tactagcggt gactttactg tagtgattaa
     4981 gtacaatcag tcaagtgaga aaggcttaca agctctgttt ggaatatcta attccaaacc
     5041 cggtcaacaa aatagttatg tagatgtgtt ccttagagac aatggtgagt tggggatgga
     5101 agcgcgtgat acttcttcca ataaaaataa cctagtatcc agacctgctt cagtttgggg
     5161 taagtacaaa caagaggctg tgactaacac tgttgcagta gtagcagatt cagtcaaaaa
     5221 aacatattct ttatacgcaa atggtacaaa agtagtagaa aagaaagtgg ataatttcct
     5281 aaacatcaag gatattaaag gtattgatta ctatatgctt gggggagtga aacgtgcagg
     5341 aaaaacggcg tttggtttta acggaacact agaaaatatc aaattcttta atagtgcatt
     5401 ggatgaagaa actgttaaaa agatgacaac aaacgctgtt actggacatt taatttatac
     5461 ggctaatgat acaacaggtt ctaactattt ccgtattcca gttctgtata cttttagcaa
     5521 tggtcgggta ttttcaagca ttgacgctcg ttacggtgga actcatgatt tcttgaataa
     5581 aattaatatt gctacaagtt atagtgatga taatggtaag acatggacta aaccaaaatt
     5641 aacattggca ttcgatgatt ttgcgccagt accattagaa tggcctcgtg aagttggtgg
     5701 acgtgactta caaatcagcg gtggtgcaac ctatattgac tctgttattg ttgaaaaaaa
     5761 gaacaaacaa gtactcatgt ttgctgatgt gatgcctgct ggagtaagtt ttagagaagc
     5821 aactagaaaa gattcaggtt ataaacaaat tgatggtaat tattacctta aattaaggaa
     5881 acaaggtgat actgattaca attatactat tcgtgagaat ggtactgtat acgacgatcg
     5941 taccaacaga ccaactgaat tttcagtaga taaaaatttc ggtattaaac aaaatggtaa
     6001 ttatttgacg gtagagcaat attcggtttc atttgaaaat aataaaaaga ctgaatatcg
     6061 taatgggact aaagtccata tgaatatctt ctacaaagat gcattgttta aagtagtgcc
     6121 aacgaactat attgcatata tttctagcaa tgatcatggc gaatcttggt ctgcaccaac
     6181 tttattacct cctataatgg gacttaatcg gaatgcgcca tatttaggtc ctggacgtgg
     6241 aatcattgaa agctcaactg gacgtattct tattccgtct tacactggta aagagtctgc
     6301 gttcatttat agtgacgata atggagcatc ttggaaagtt aaagtagtgc cacttccttc
     6361 tagttggtca gcagaagcac aatttgtaga attgagtcca ggagtaattc aagcatatat
     6421 gcgtacaaat aatggtaaaa ttgcatattt aacaagtaaa gacgcaggta ctacttggag
     6481 tgcaccggaa tatttgaaat ttgtttcaaa tccaagttat ggaacacaat tatcaatcat
     6541 caattatagc caattgattg atggtaaaaa ggctgtcatt ttaagtactc caaactccac
     6601 aaatggtcgt aaacacggac aaatttggat tggtctaatt aatgatgata atacaattga
     6661 ttggcgttat catcacgacg ttgattatag taactatgga tactcatatt caacattgac
     6721 agagttacca aatcatgaaa ttggattgat gtttgaaaaa tttgattcat ggtctcgtaa
     6781 tgaacttcat atgaaaaatg ttgtaccata tataacattt aagattgaag atctgaaaaa
     6841 gaattaaagc tgaaatttga aaatatataa aaagaggata aaaattatgg taaattacgg
     6901 tattgttgga gctggatatt ttggagctga tttagctcgc tcaatgaaca aaattgaaga
     6961 tgcaaaagtg gttgcggtat ttgacccaaa tcatggagaa gaagttgctc aagagttggg
     7021 atcagatgtt tgtgcaagtt tagatgaact tgtagcacgt gaagatattg attgtgtgat
     7081 cgtagcttca cctagctacc ttcaccgtga accagttgtg aaagctgctc aacatggcaa
     7141 acacgtattt tgtgaaaagc caattgcatt gtcttatgaa gattgtaaag ccatggttga
     7201 cgcatgtaaa gaaaataatg tcatctttat ggctggtcac atcatgaact tctttaacgg
     7261 tgtacaccat gctaaagaat tgattactca aggtaaaatc ggtaaagttc tttattgcca
     7321 tgctgctcgt acaggttggg aagaacaaca accaactgta tcatggaaga aacttcgttc
     7381 tcaatctgga ggacatttgt accaccatat tcatgaatta gattgcattc agtttatcat
     7441 gggaggactt cctgaaaaag cgacaatggt aggaggcaat gtatatcata aaggtgaaaa
     7501 ctttggtgat gaagatgata tgctcattgt aaacttagaa tactctgatg atcgttatgc
     7561 tgttttggaa tatggtaatg ctttccgttg gggtgaacac tacgtcttga ttcaaggaac
     7621 tgaaggagct atcaaacttg acttgttcaa tactggcggt actcttcgtg ttaaaggtga
     7681 aggagaatca cacttcttag ttcatgaaac tcaagaggaa gatgatgatc gtacagctat
     7741 ctataccggt cgtggtatgg atggagcaat tgcgtacggt aaaccaggag tacgttgccc
     7801 attatggttg caaacatgta ttgataaaga aatggaatat ctacatgaca tcattaaagg
     7861 tggagaaatt acagaagaat ttgaaaaact tctcaatggt gtagctgctt tagaatcaat
     7921 cgctaccgct gatgcatgta ctttatcagt taaagaagat cgaaaagtaa gtctttcaga
     7981 aatcacaaat gcttaacttt tgtaaaacag aatagtaaat tcttgtcatt atataatttc
     8041 taaagttctg tgatacaact cattgaataa agaaatagag atgggactgg gataatgccc
     8101 agtcccattt tttatcaaaa agtaatgaga tcaaaaatgt gggagtgttg aaatgaagat
     8161 tataggtatc gatattggcg gaacaacaat taaggcagat ttatacgatg agtttggaac
     8221 gagtttgaat catttcaaag agatagaaac aattattgac tatgatttgg gaacgaatca
     8281 gatattaaat caggtctgtg atttaattgg tgagtatact ttaaatcatt caattgatgg
     8341 tgttgggatt tccactgctg gagttgttaa tgctaatact ggagaaatca tctatgcagg
     8401 ctatacaata ccagggtata tcggagtaaa ctttactgcc gaaatagaaa aacgttttgg
     8461 gttgtatact tttgttgaaa atgatgttaa ttgtgctgca ttaggtgaat tgtggaaggg
     8521 acaagccaaa gataagaaaa atgtagtaat ggttactatt ggaacaggta taggaggcag
     8581 tattattgtc aacggacaaa ttgttaacgg atttaactat actgctggtg aagtaggtta
     8641 tattcctgta ggtaattcgg attggcaaag taaagcctca acaaccgcat tgattcattt
     8701 atatcaaaaa aagagcttga aaactaatca aactggacgt actttcttca ctgatttaag
     8761 atctggagat aaagttgctg aagaaacttt tgaaattttt gtagaaaatc taacaaaagg
     8821 tttattaacg atttcttatc tacttaatcc agaaattctc atattaggag gtgggattct
     8881 ggatagtaag gatattttgt tacctgaaat tcaaagttct ttagctaaaa atgcaatgga
     8941 taataggttt ttacctaaaa atcttgtggc agctacatta ggaaatgaag ctggtcgtat
     9001 aggagctgta aaaaatttct tagatagaat ttctaataaa tagtatgtaa gataaggagg
     9061 tgtcacaatg actaactctg tattttcgac aatgcaagat attgagaatg ttgcaaccga
     9121 tattataaaa tcatatgata atgagattta tacttataaa gctgtttccc aagaagaatt
     9181 ggaaaaacta gaaaaaagtt atgatgaaaa aagtcacgaa gaattagttt caatagaaag
     9241 caatttagaa atgaaacaac agaaccttat tgatgaggtt aataaaacaa tcaaggaaaa
     9301 tgatgcaaat attcagtata tttcatcaag taggagagga gaatttgtag aaaaaattat
     9361 tggtagggtg gtagaaaaat atggccatta gtcagatgaa aagaatctct ctactatttt
     9421 ctaaaagtag tcttgatgat gttttaaaaa ctattcaaga actagagtca gtgcagttcc
     9481 gtgatttaaa ggttcaggat aattggtcag aagctctaga aaaagatgaa gttgtatttc
     9541 caactattca aatttttcat acttctaatt ccaatcatgg ggttattgag ggaaatgatg
     9601 ccttgactta tttgatgaat caacaacaac atttagaagc aactgtagag aaattacaag
     9661 aatacctacc gaaagaaaac acgtttaaat tattgcagca acctccgata actacctctt
     9721 atgaagaatt agagaaattt ggtaaagcta atgttgctga gggtgttctt aaaaaagtga
     9781 atcatcaaat taacagagtt catgaattag aaagacacat tcaaagtaat aatgaggaaa
     9841 tagagcgatt aataaagtgg gaaaaattag aaattgttcc tgcgaattta gaacaatttt
     9901 ctttctgtaa aggaaaagtc ggaacaattc caaggactga agataatcgc ttatacaata
     9961 gtcttttaga aaacaatatt gaagttcaag aaatattttc taatgataga gagtacggtg
    10021 ttgttgtttt ctatcagtct agttactcta tagattttga tgaatactta tttgaaccat
    10081 ttgattattc tagaaaggaa ttaccgaagc agcgagtagt agatttagat caagaaaaca
    10141 tgcagttaat aactgaaaaa gagaatatta tcgcatcgtt gcaagattca aagaaatatt
    10201 tgatagattt acaatggcaa atagactata ttttatctat ctatgctcgt caaatctcta
    10261 agaataactt tttgtgcact ccgcatctag ttgcattaga aggatggata gaagaaactc
    10321 gtattttata ttttataaaa gttatggatg agcattttgg acattctatt tatatttatg
    10381 aatcggaaac attgacggat aatcaagatg aaatacctat caaattaacg aatcattctt
    10441 taattgaacc atttgaatta ttgacagaaa tgtatgctct gcccaaatat tatgagaaag
    10501 atcctacacc tgtattagca ccattttact ttacattttt tggaatgatg gttgctgatt
    10561 taggctatgg tttactattg tttttaggaa caatgttagc attaaaaatt tttcatctac
    10621 cttcagcaac taagagattt ttaaaattct ttaatatatt aggggtagcc gttgcaattt
    10681 ggggtggaat ctatggctca ttttttggat atgagttgcc atttcatctg atatctacaa
    10741 cctctgatgt tatgactata ttagtagtgt cagttgtgtt tgggtttatt acagtatttg
    10801 caggtttgtt agcttcagga ctacaaaaag taagaatgaa gaaatatgca gaagcatata
    10861 attcaggatt tgcgtggtgt gttattctgc ttggcttgtt atttattgct gttggaatgt
    10921 tgatgcctga tatgagaccg ttatttgtat tagggaaatg ggtatctatt tttaatgctg
    10981 tggggatttt gattgtttct attattcaaa ccaaaagctt gtcaggtatt ggagcaggat
    11041 tgtttaatct atataacatt tcatcttata taggtgattt agttagtttc actcgattga
    11101 tggcattagg attatctgga gcaagtatag catcagcttt caatttaatt gttggtttgt
    11161 ttccgggaat attggctaaa ctgacaattg gattagtatt attcattctt ttacatgcga
    11221 tcaatatttt tctatcgtta ctatcaggat atgttcatgg agcacgtctg atatttgttg
    11281 aattttttgg taagttttat gagggtggag gaaaaccatt tcaacctttg aaggcttctg
    11341 agaaatatat taaggttatt acaaagaatt aatggaggat atatataatg gaacatttag
    11401 caacttattt ttcaacctat ggaggagctt tcttcgctgc attgggaatt gtattggcgg
    11461 ttggattaag cggtatgggg tctgcttatg gagttggtaa ggctgggcaa tctgccgcag
    11521 ctttactgaa agaacagcct gaaaagtttg cctcagcttt gatattgcaa ttattgcccg
    11581 gaacacaagg attatatggt tttgttattg gaattttaat ttggttgcaa ttaactccag
    11641 aacttccttt agaaaaaggc gttgcttatt tctttgtagc tcttccaatt gctattgtag
    11701 gatacttttc agctaagcat caaggaaatg tagcagtagc gggaatgcaa atcttggcta
    11761 aaagaccaaa agaattcatg aagggagcaa ttttagctgc catggtagaa acctatgcaa
    11821 ttcttgcttt tgtcgtatca ttcattttga cccttcgtgt ataagaaata aatttgcaat
    11881 tcaaaggagg tgtctaaatg agcaatttag aaaacttacg agagtctgtt attgaacaag
    11941 ctcatgaaaa agggcgtatg aaattattgg attccaaaaa gaagattgat gatgaatttg
    12001 aaatgcaaaa gtcgctcatt ataaagaaaa aagaagctga acatgaacga aagttaaaag
    12061 aattgcaaca gaaatatcaa ataatttttc aacaattaaa aaataaggaa cgccaatcaa
    12121 cgttagtatc aaaacagaaa atattaaaag aactttttca atctgcttta ctagaaatgg
    12181 aatcttggag tgcagataaa gaaatggagt tcatctatcg aattctggaa cgatattcac
    12241 aacaagaggt catagtaacc tttggggaac ggactttagc taaattcaat ttggaacaat
    12301 tagagaaatt gaaattctct tttccaaatt atttatttag tgaacaacct atctcaaatg
    12361 aatcaggctt acttatttca ataggtaaaa ttgatgataa ctatttgtat aaaacattaa
    12421 ttggatcgat ttctaaggaa gaaagttcaa gtatcgcaaa tcaaattttt atcaattaag
    12481 gatgaaattg gttaatcctt cttagaaatt tggagtattc caataaaatt agaaaggtat
    12541 tttatggata ctaatctttt ttcaaaaata aatacgacga tttcggtaaa agaaaacgat
    12601 tttattacag aagaaaaatt tcaaaaaatt atacaatcca aagatacgga gacattggca
    12661 tttatcttag aatcaactcc ctatcattta tcgattgaca tcttagaaga tcctagtcag
    12721 acagagattt cgctaatgac aaaattagtc aatgattata gatgggccta tgctgaaagt
    12781 ccgtctgata taattgtgac tttatttgct ttacgatatg tttatcataa tatcaaagtt
    12841 ttattaaaat ctaaggcggc aattaagaaa gatttttcta aattattaat tccaataggg
    12901 atttttgata tagaaagttt aaaacattta gtttcttcct tacattcaga tacacttcct
    12961 gattttatgg ttcgtgaagt agaatcaatt tggaatgagt atgaaacttt taataatatt
    13021 cgtgtacttg atgtcggagc tgatctagca tattttaaac atctgaaact tttatctaat
    13081 gagttagatg aggtactgtc tcaggttatt gtcgaaatga ttgactttta taatattatt
    13141 actgtaaaac gtggtttatc tcaaaataag agtcatgggg atattttaca attactttca
    13201 gatgaaggaa gtatttctgc taaagaattt atatacattg tagaaaatca agaaatattt
    13261 gtgtggttca ataaaataaa tccaagctta gattcaatct tttcaactta tgaattgaag
    13321 atgcaggacg caacaatttc atcttctgag ttagaatttt tatgtgattt actattgtat
    13381 aaaactttag atcaaggaag gtacaatgta gaggggccgt tagttcttgc tagatattta
    13441 ttgggatgtg agtttgaagt aaagaatctc agaatgatca tatcagctct tcaaaataca
    13501 attccctttg aatcaataaa agaaaggata cgcccacatt atggaagcta ataagtataa
    13561 aattggcata attggtagcc gtgatattat tttaccattt agcatgattg ggtttgatat
    13621 atttcctgcc taccaagaac aagaagctat aaatacacta agaaaattag ctcaatctga
    13681 ttatggtgtc atttatatca ctgaagacat tgcttcaatg atattagata caattcgcca
    13741 ttatgattcc caagttgtgc ctgctattat tttattaccg actcataaac aaggtttaaa
    13801 tttaggatta aaacgtatag aggataatgt agagaaagca gtaggacaca atattttata
    13861 ataatgtaca aaattgtctg taatattatt ctataatttt tggacttagt aaggagaata
    13921 actttgactc aagggaagat tataaaagta tcgggacctc tagttattgc atcaggtatg
    13981 caggaggcta atattcaaga tatttgccgt gtaggtaagc tagggttaat cggtgaaatt
    14041 attgaaatga gaagagatca ggcatctatc caagtctatg aagaaacatc tggtcttggt
    14101 ccgggagaac ctgttgttac aactggagaa cctctctcgg ttgaattagg gcctggattg
    14161 atttctcaaa tgtttgatgg catacaacgc ccattagatc gatttaaatt ggctactcat
    14221 aatgattttc tagttcgtgg ggtagaagtt ccaagtttgg atagagatat taagtggcat
    14281 tttgattcca ctatatcaat tggtcaaaaa gtgagtacgg gtgatattct tggaactgtc
    14341 aaggaaaccg aagtagttaa tcataaaatt atggttcctt atggaatatc tggcgaagtc
    14401 gtttctattg cctctggcga ttttacaatt gatgaagttg tatatgaaat aaaaaaattg
    14461 gacggtagtt tctataaagg aacacttatg caaaaatggc ctgtccgcaa ggcgcgtcct
    14521 gtttctaaac gtttaatccc agaagaacca ttaatcacag gtcaacgagt tattgataca
    14581 ttctttccag taaccaaagg gggagcagca gctgttcctg gaccgtttgg agcaggaaag
    14641 acagttgtac aacaccaagt agctaaattt gccaatgttg atattgttat ttatgtcggt
    14701 tgtggagaac gtggaaatga aatgacggat gtactgaatg agtttcctga gttgattgac
    14761 cctaatacag gacaatcaat tatgcaacgg acagttctga ttgctaatac ttcaaatatg
    14821 cctgttgctg ctcgtgaggc ttcaatttat acaggaatta ccatggctga gtattttcgt
    14881 gatatgggct actctgtcgc cattatggct gattcgactt cacgttgggc agaagcgcta
    14941 cgtgaaatgt caggacgtct agaagaaatg cctggtgatg agggttatcc tgcttatctt
    15001 ggaagtcgta tcgctgaata ttatgaaaga gcgggacgtt ctcaggctct agggcttcca
    15061 gaacgtgaag gaacgattac tgctattgga gctgtatcgc cacccggtgg agatatttca
    15121 gaaccagtta ctcaaaacac tttacggatt gtgaaagttt tttgggggct tgatgctccg
    15181 ttggcacagc gacgtcattt tcctgcaatt aactggctta cctcttattc actctataaa
    15241 gacagtgtgg gaacttatat agatgataaa gagaagacag attggaatag taaaataact
    15301 cgtgcgatga actacttaca acgggaatct agtttagagg aaattgttcg tcttgttgga
    15361 attgattctc tgtctgaaaa tgaacgacta acgatggaaa ttgctaaaca aattagagaa
    15421 gattatttgc aacagaacgc ttttgattcg gtagatacat tcacttcgtt tgcaaaacaa
    15481 gaagcaatgt taagtaatat cctaactttt gctgatcagg caaatcatgc tttagagttg
    15541 ggttcttact ttacagagat tatagaaggt accgtggcag ttcgagaccg tatggcgaga
    15601 agtaaatatg tttcagaaga tagattagat gaaatcaaaa ttatttcaaa tgagattaca
    15661 catcaaattc aattgatatt agaaacagga ggtctataaa tgagtgttat aaaagaatat
    15721 agaactgcta gtgaagttgt tgggcctctt atgattgttg aacaagttaa taatgtgtct
    15781 tacaatgagt tagttgaaat tcaacttcat aatggagaaa ttcgtcgtgg acaagtttta
    15841 gagatccacg aagataaagc aatggttcag ctttttgaag gatctagtgg aataaattta
    15901 gaaaagtcta aaattcgttt tgctggtcat gcactagaat tggctgtatc tgaggatatg
    15961 gttggtagaa tttttaatgg gatgggaaaa ccaattgatg gtggaccaga tttaattcca
    16021 gagaaatatt tagatattga tggtcaagct attaatcctg tatctagaga ttatccagat
    16081 gaatttattc agacagggat ctcctctatt gatcatttga atactcttgt acgtggtcaa
    16141 aaattaccag tattttcagg ttcgggctta cctcataatg aattagcagc tcagatagca
    16201 agacaagcga ctgttttaaa ttctgatgaa aattttgcgg ttgtatttgc agcaatgggt
    16261 attacttttg aagaagctga gttctttatg gaagaactca gaaaaacagg agcgatcgat
    16321 cgttcagtct tatttatgaa cttggcaaat gatcctgcaa ttgagcgtat tgcaactccc
    16381 cgcattgctt taactgcggc agagtatcta gcttttgaaa aagatatgca tgttctagtt
    16441 atcatgacgg atatgactaa ctattgtgaa gcgttacgtg aagtctcggc agctcgccgt
    16501 gaagttccag gtagacgagg ctatccggga tatttatata caaatttatc aactctatac
    16561 gaaagggctg gtcgcttagt tggtaaaaaa ggttcagtga cacagattcc tattttaaca
    16621 atgccagaag atgacataac acatccaatt cctgatttaa ctggatacat tactgaaggg
    16681 caaattattt tgtcgcatga gttgtataat caaggttatc gtccaccaat caatgtttta
    16741 ccttctctct ctcgattaaa agataaggga tctggagaag gtaaaactcg tggagatcat
    16801 gctccaacta tgaatcaact gtttgcagcc tatgcccaag ggaaaaaggt tgaagagtta
    16861 gcagtagtat taggagaatc ggctttatct gatgtagata aattgtatgt gaagtttaca
    16921 aagcgttttg aagaagagta catcaaccaa ggattttata aaaatcgaaa tattgaagat
    16981 acgttgaatc ttgggtggga attactatca attcttccta gaacagagtt aaaacgtatc
    17041 aaagatgatt tgcttgataa atacttacct ttggtagaag tttaatccag aaatggagtg
    17101 attatctatg gtgcgtttga atgtaaaacc aactcgtatg gaattgaata acttaaagga
    17161 acgtttgaaa acagctgaac gtggacataa gttattaaag gataaaagag atgaattgat
    17221 gaggcgattt atttctttga ttcgtgagaa taatcaactt cggaaagaag tagaaagtta
    17281 tctaattgat aatctaaaag cctttgcagt tgctaaatca ttaaagaact ctctaatggt
    17341 ggaggaatta ttttcaattc catcgaaaga aattgaatta tttgttgaga aagaaaatat
    17401 catgagtgta acagttccta gaatgcatat gaatattact tctcaaaatg agaacagtga
    17461 atacagctat ttatcttcta atagtgaaat ggatgatgta tttgctacaa tgaatagttt
    17521 aattgataaa ttactaagac tggcagaagt tgaaaaaacg tgtcagttaa tggctgatga
    17581 aatagaaaaa acacgtagac gtgtaaatgg attagaatat tcgattattc caaacttgtc
    17641 agaaactatt cattatatag aattgaaact agaggaggca gaaagagcca atttagttcg
    17701 gattatgaaa gtgaagtaga tcctttattt agattttaat tagatgaacc aatatcagct
    17761 tggataaggc ggtaagcctt tctaagcttt tttattgaca gtatcaggat atctttttca
    17821 aaattttggt ttgttagata atgaaaatgt ttctaccgat ttagatttag gattaataag
    17881 tcgtaaatgt aattttaaag aaaaagataa gttaaaaaaa gatgtattag caagagttgg
    17941 tctaactcat attcatctag aacaaaagat atatgaattg tctggcggtg aagcataacg
    18001 tgttgcttta gcgaaaatca ttcttaaaaa tccaccatta atactcgcgg atgagctgac
    18061 tgcatcactc gatccgacga cttcacaagg aattatgaaa ttattattag atatgaaaaa
    18121 tgaaaatcgt ctaatcatca ttgcaactca taatcccgat atttggaatc aagcagatga
    18181 agttataaat ttaaatcaat tatagttaca gccaatatat attttctata ttttaaagtt
    18241 attttatctg aatccgtaaa agcagttcaa tcttgtactg acccccaaaa gttagacaat
    18301 taatttatcc gaaggattta gttctgtatt gcacaggact aagtcctttt agttttatct
    18361 taattcgttt gttgttgtaa taatcaatat agtctacaat agcttgttcc aattgattaa
    18421 gcgactgaaa tgtcttctca taaccataaa acatttcgga tttcaaaatg ccaaagaagg
    18481 actccatcat gccattgtct gggctgtttc ccttgcgtga catggatgct tgaattccct
    18541 tactctctag gaaccgatga taagaatcgt gttggtattg ccagccttga tcgctatgga
    18601 gaatggtatt ctcataatgt ttctctgtaa aggcctggtt taacatagct ttcccttgtt
    18661 ctaagtttgg tgaagttgaa agattatagg cgataatttc gctgttaaag ccatctaaaa
    18721 ctggcgataa atagagcttt tgactgcttg ctggaatggc aaactctgtc acatccgtat
    18781 agcacttttc cattggtctc gatgcttcga actggcgttg aatgagattc tctgctttct
    18841 tgccaatctc tccttggtag gaggaatact ttcgtttccg acgaattcga gctgttaaac
    18901 caagaacttt catcagacgt tgaactttct tatgattcac cacaaaacca cgatttctta
    18961 gttcaagagt aactctacga tagccataat ttcctttgtg ctcagtaaaa atagcttgaa
    19021 tttcagcttt aagatcttta tctttgtcaa gcccacctag tcccttcaac tgatagtagt
    19081 aagtcgagcg agctaaacgt gctgtttcaa gaagtaaatc taattgaaat cctcctgaag
    19141 ccatttctct aactatctct gcctttctcg ctctagggct tcgtccctgt cttccagctc
    19201 ttttaacttt tttaagtaag ccacctcggt acgtaagcgt tcattctcct cttgaagtcg
    19261 ctctagttct gtcatttctt cccaagtttt cttacgttta cgtcccattt taggtactct
    19321 ctctcttgtt ttctcaacaa tagtataccc gtttttcttg tattgcgcca gccaatttgg
    19381 aagcatacca cgatttggga gagcatattt gagagaaact ctatcttgag accagttttc
    19441 atgtaaaact ttatcaatca tttcttgttt tagttctgga gaatagtatc gatttttccc
    19501 ttttttga
//
LOCUS       DAVAGB010000039        18975 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVAGB010000039 DAVAGB010000000
VERSION     DAVAGB010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18975
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.039"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(66..428)
                     /locus_tag="VQO19_001565"
     CDS             complement(66..428)
                     /locus_tag="VQO19_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349799.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNIEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(719..2599)
                     /locus_tag="VQO19_001566"
     CDS             complement(719..2599)
                     /locus_tag="VQO19_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET1349800.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVMGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAGTIADIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(2593..3462)
                     /locus_tag="VQO19_001567"
     CDS             complement(2593..3462)
                     /locus_tag="VQO19_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET1349801.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLYRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(3546..6191)
                     /locus_tag="VQO19_001568"
     CDS             complement(3546..6191)
                     /locus_tag="VQO19_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HET1349802.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEVTIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGEQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(6282..7562)
                     /locus_tag="VQO19_001569"
     CDS             complement(6282..7562)
                     /locus_tag="VQO19_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HET1349803.1"
                     /translation="MIYPKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            7733..9817
                     /locus_tag="VQO19_001570"
     CDS             7733..9817
                     /locus_tag="VQO19_001570"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HET1349804.1"
                     /translation="MKPLLETIDTRFGTASKHAFSWGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLVSSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKSSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKTCQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(9857..11536)
                     /locus_tag="VQO19_001571"
     CDS             complement(9857..11536)
                     /locus_tag="VQO19_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HET1349805.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYNQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQQVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PELSKKEVVQELAFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQ
                     DEIYVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            12292..13521
                     /gene="arcA"
                     /locus_tag="VQO19_001572"
     CDS             12292..13521
                     /gene="arcA"
                     /locus_tag="VQO19_001572"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HET1349806.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            13579..14595
                     /gene="argF"
                     /locus_tag="VQO19_001573"
     CDS             13579..14595
                     /gene="argF"
                     /locus_tag="VQO19_001573"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HET1349807.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            14760..15707
                     /gene="arcC"
                     /locus_tag="VQO19_001574"
     CDS             14760..15707
                     /gene="arcC"
                     /locus_tag="VQO19_001574"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HET1349808.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            15918..17429
                     /locus_tag="VQO19_001575"
     CDS             15918..17429
                     /locus_tag="VQO19_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HET1349809.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSDL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            17451..18782
                     /locus_tag="VQO19_001576"
     CDS             17451..18782
                     /locus_tag="VQO19_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HET1349810.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICQDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNDLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIHIDIRTPVLADKE
                     ELVELLRRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
BASE COUNT         5331 a         4294 c         3904 g         5446 t
ORIGIN      
        1 aactaggatt ctagttttgc aggaagtcta ttgaaatact aagcctacac agactgattt
       61 caattttacc attcttcata gtcaaaacca tcataatctg gatattgttc tggcgacgtt
      121 ccaaccgaac gtacgagata agcttcttcg tcctctgtct cgatttctct cagcacttgg
      181 cattcaaaac gccattcatc accgaagtcg aaaataaact taaatttttg tttgacactt
      241 aggctatcca gatagacatt ttctgtgtaa cgttcttcaa catcgtcact aacaaagcta
      301 agaaagtaag aatctgcatg actccactca atattatcca tgaaaaatgc gtgagcatga
      361 tcatttgcaa aatcaaaact ccataaaatc acatctgcta gttccgctaa cgtttttgtt
      421 tttggaatct atatatgtcg gtagcaacct tttttaaatt tgacggaaat gatccaagcc
      481 tctacagatg ctggcttttc agcttctatt tcttgtttta ctaattttaa ctgtagcatt
      541 tgaaaccaga taattcttct gtttcacgcg aaacaccctg cgccaagcaa ggtgttcttg
      601 tttttatact caatgaaaat caaagagcaa actaggaagc tagctgcagg ctgctcaaaa
      661 cactgttttg aggttgtaga tggaagctga cgtggtttga agagattttc gaagagtatt
      721 aagtcgtata aatcgtcgaa gctgtcgcaa tggtatgcca ctggttagct gtagttgctg
      781 cgaaatcctt gtctgcgtag aagtcagtaa atggtaggat ttcaacttcc agctcgtcga
      841 tgcggtcaag ctggccagcc agataaacct cgatacggct ttctgctcgt ttgatgcgtt
      901 gcaagagtcc gcccatacgg atgtcaactg tatccaaacc aaagaccttg ttttctttca
      961 gccattggtg actaaagagg gcatggaagt cttcaatttg gcttctaagt tctggtaatt
     1021 cttgtctggc gatttgttgt aaactttctt tatcatccgc ttggtaggcc tgacgaatgc
     1081 gtcgtcccac atctactttg ctacttaaaa tagcattcaa ctgggcctga gtttcaaaga
     1141 gataagcata gtttccagct ttttctttaa tgtcagcaat agttcccgcc gcctgagcga
     1201 agtgtggctt gtcctgttca ggtgtcatgt gtcggtcaag tatcggacag agaacatcct
     1261 gataaaagac atagcggttg ggattgatgc cactgagatt acctggtagg tctggtaaga
     1321 ggttggcaag gtcaatctgc ataaaatcct caaccgttag accagtattg gtcttgaaat
     1381 gcgcagacaa actatctagg tcattgcgat agctgagttc tgcccagatt tgcaagcttg
     1441 gtaggataga gaactgggca gtttcaccac cattgtctcc ccaacccatt acgatgactt
     1501 ctttaatctg attggcacgg caggctttat tagcctcgat agccactaga cggctaaaat
     1561 ggttgtgagg tgtaaagcca atccacttcc aagctccccc tgcaaatgca aggtcatggc
     1621 taatcttgtg atgattgcgg aaattacggt tgtatttttc ctcgctatcc tgataataat
     1681 cccagtaaac cagagtcaca cggtctttga gacggtctag gtagacacga gtttcctctg
     1741 gaatttccac atcacgatcg tactggccat ccgctgacat gagtttgaag aacatatcac
     1801 tccacatctg gcagtggaaa ccatatttgt cagcaatatc cagcacgcgc tccaagtgtt
     1861 ggcacatgag gagactacga tccacaacac cgttcaaaat caggtagcgt cccaaaccaa
     1921 ccaagtgggc ttcgtccatc ccgatattga ccttgcgagt cttcagttta gacaacgtgg
     1981 caaacatgcc atcaatcagg tcataaacct tttcttcgcc aatgagaaga atgtcctcta
     2041 catcacggag ctcctgcact tccttgacac cccatttgac aaaggccgac aagtgggcca
     2101 aggtctggat gcatggtaca aaggtcatgt caaactgttg agcataggct tcgatttcct
     2161 gcaactcctc tgctgaataa gctccacgga aatagccaaa gtaaggctgt ccttcaatct
     2221 ggtaagtgtc ttccatgtaa agctcaaagg ttgagtagcc catgagagcc aagacctcaa
     2281 tcatctgctt ggcagaagcc acattcagca ccgcatttcg agaacagtca accatgtaag
     2341 ccaaatcttc gtaagctgct tgttcctcaa tctctacttt atcagcttct gctagaactg
     2401 ttaccaacaa ggataaggca cgataaagtt ggtgaggttt gcggtaggtc aattgatagt
     2461 gaccttcctc accctcgata gagatagagg cttggtcaga ctgagtgaca gccacttcca
     2521 catctggtag agaaatgtga ccttttaaaa cctcaatagc ttgcgtttgt ttgggactaa
     2581 gtcctgtaaa tcttaccatt gcttttcctc ctgtagccag ttgacaaggg caccgtagag
     2641 attggcatct gcgtgatagg tgcaggcctg gataactggt gcgaccgtgt attcttcgta
     2701 ggcatcgaca aagtcttcaa cagccttctt aacaccttgg ataaaatctg gattttgact
     2761 gatagagcca cccagactga tgacatctgg atcgatcaga tactggatat tgagcaagcc
     2821 ttgcgtcaga ttgcggttca tgcgctcaat ggcttcttga caaagagcat taccagctgc
     2881 ggcctcttgg taaatcttgc gaccgtccca atcagtatga ccagattttt caatcacgta
     2941 tcgtaccata ttcccagttg atgctagttg cgaccagtta ttaagttttt cagcaggggc
     3001 aagggttgtc atgtagccaa attctccacc cagaccgtgg cgacctcgat aaagtctacc
     3061 attgataatc atggctccgc caatccctgt cccaatcacg acacaggctg cattttcaag
     3121 ctctggatga gctagtagtt cactgagtcc aacgcagttg gcatcatttt ctaaatggac
     3181 aggtagctga taagagctaa gcgcctcata ccaagaaaag ccatggatgt agggcaccgc
     3241 actgaagcca tcaatcacac ctgtctcttg attgaccgca cctggaacgc tcatagcaat
     3301 cccactgtaa tcctgttctg acaagcgttg atctagccac gctagtaaat cctccaagtt
     3361 ttcaggcgtt gaaatacttg tcttatccag tattttccca tcaggagtca gactggcaaa
     3421 cttaatccca gtccctccga tatcaatcgt tgcaatggtc attgttttta ccataaaaag
     3481 gggcgaatca gcagttagtt cttacttttt cgcccctcct ttcttttgat gtttactttt
     3541 tgaaattaaa tttcttcttt tttgatgaat tctgtacgaa tctcttgtgg agccaatagt
     3601 cctgaatgaa ctggatatgg tcgctcaagt aagtcaagaa tggtttgttg atgttctgat
     3661 atgcgcacat tttcttgact catattatag taacggagga catagccttc ttcattttcc
     3721 gccactttaa aggctgttgg acaaacttgc ggtatgctga gaacagaatg gctcaagagg
     3781 ctaccagtcg caaccacgct tccttcctgt ctagcaagct gaaggctggt aaacggtgtc
     3841 tgcaaggctt tggcacgacg ataggctgag aagcgttctt gggcttggtg gcattcaatc
     3901 gcaaattcga cttcaaactc acgcaagcat tgtgcttctg gcgttgggaa gtagccccag
     3961 tcacctagct cacctgatgc acgcaaaatg gtcacggcaa tggtgttatc cccaaggatt
     4021 tcgtattcat tcaatccctt gttggataca gtcacccctt tttcatcgtc atacagactg
     4081 acaaaagctt gttggtgttg aggattttca ggattttccc atgaagcagc tggtttgttt
     4141 ggtcgtgtca ccacctcata gatactttca gaatcattgc ttggacgcgt gttatgagtc
     4201 ttgaccaaga gacggatacg gtgatccttg gcagtgttag taaagcgagt cttgaagcgg
     4261 atttgtggat tgtcaacaaa gacaatcaac tcagtttcca gaggaatgtt tgtcaattct
     4321 tctgaccgtc cagcctcacg cttcataaac tcgatgatac cttgttgctc ttcttctagc
     4381 ttttcatccg cactgacagg cacggtcaat tcatgtttga gcaagatttt agcatagcga
     4441 tctgtgtttt ccaagacctc gtggccctta agctctgcaa agattggctc tgttcctttt
     4501 ggttggaaat agatatactc gtttccgatg tcaccccggt cttcgaagcg gataaaatct
     4561 tcataggctt cgtgagttgt cttatcatag actgtgatgt tgtcatccac actcaccgtt
     4621 acgaatggtg tatcaatcac tccgttttgg taaataccct cacggtgttc ttgttctcct
     4681 tccagcaatt ggaaggttgt ccaagaaagc ggtgctaggt gaactggaat ggtcacgcgc
     4741 acttgtcgag caatacgagc ttggcggaac ttatcttttg gtaaatcgta ttcaaaatta
     4801 gctccgaggt cttcgattgt aacctctaca ggacgaccat ccaagtcctc cacacggtaa
     4861 cttggcaaga taagagcagc catctttttg tagccttctg ttgggtgcaa ttccttgaaa
     4921 tcacaagtcg ccacatcaat cactgtgctg acagtatcga ccttatcatg caagcctgtg
     4981 ttaatgacag taaagagata gtcactttga gccttatccg tagcaatttt acccttccac
     5041 tcgttgagca aattactttt aacaaagttt cctacttggt tgaccttggc aaaacgcgtt
     5101 tccatctcgc ggtgaacttc gtccacgcta cagccacaga tactatcatg tggcgcattc
     5161 tgcaaaagtg ttttccaagc ataggtcaac tggtccttgt ggttgtgtcc accagtgata
     5221 atagtcaagg gttctaccac ttgctctagg aggttgctat tttcttggaa ggcttgtttt
     5281 aggtaaatgc gggatgaaga agtgttggca agtgtgtacc agccatctgt ttcctgactg
     5341 gtcaactcgc ctgtaacagt tgataagtgt tcaggaagcg caccttctac agcttgaaca
     5401 tattcatcaa aagaactatg aacaaagatt acatccggga agagttcatt tgccacacga
     5461 atggcttcgc tcagattttt ctgtacaggc tggtggtcac agccgttcat catcaaccat
     5521 tggttggtcg aagcgtaggc acgcacatct gacaattttt gtttccagaa ggtcaaggcc
     5581 tcatctttgt caactgggat ttcattccca ttactgtacc agttggcaaa gagaatacct
     5641 aaaacacgac taccatccac accctgccag tacatttctg aaaactggga tgtaaactgc
     5701 tcatcttcaa ggacttggtt gtcaaatcca atcggcttca caccacgacc aaaggccgcc
     5761 acgtgaatgc ctgatttttg aagaatttga ggcgcttgtc ccatatttcc aaaggtatct
     5821 ggaaagtagc caatctgggt tgatttaccc catttggcag cttcttgttg accaatcaag
     5881 gtattgcgga cattggcttc actggagatc aagtagtcat cctgcaagat gtaaaaggga
     5941 ccaattttaa gtttgccctc gtcaatgtag cgttggacct tgtcgcgatt ttcagggcga
     6001 atttgtaagt agtcatcaag gacaatagtt tgtccatcca agtggaaact cttgaactca
     6061 gggtcatttt caaagagatc aaagagattg tcaaacaatt ccaccaactg catacgatgg
     6121 ctttcaaaag gcaagtacca ctcacggtcc cagtgactat gtgagataat atgtacaaca
     6181 acattttcca tgaagtaaaa cctcattcta aatttaaatt ttaacgtttt aaatgtaaac
     6241 ttgtgattct gataagaatc ggttgagcta aagcgagccc cttagcgaat atccaagtaa
     6301 tccaagacca actcacagaa catcatgtta gcccaggaga accattcacg agagtagagg
     6361 gtcggatcat ctacgtggaa gctttcgtgc atgacacctg taccaccatc gcaggcaacc
     6421 agctgatcca gcaagaattt tttctctgcc ttatctcttg ttgtcaatcc ttggatagaa
     6481 agggcgattg gccagatata gcgatagaag gtatgagaac ttccgagacc gctagcgtat
     6541 tctccttggt agaagtatgg attttcagag ctcagaatgg tacggcgagt ggcttgatac
     6601 acttcatcat cgatcgaaca gtagcccaga tagggcgcag ctagtagact tggtacattt
     6661 ggatcatcca tgatgctggc atttcctagg ccatctactt caaaagcgta aatcttttcg
     6721 cccttgctgt tggtggtgta agcgtagttt tcgattcctt cttggatttc atcctgaaga
     6781 cgcttggcat cagcaataac actctggcta tcagctaggt ttaatgctgc gaagatttct
     6841 tgcacataac ccaagactac tacagcaaac atatttgacg gaatcaagta actatactgg
     6901 caacagtcat cactcggacg aaaggctgac caagtcatac ctgtcactgc aaagtcaggt
     6961 ccaaagccat catttaccaa ggtgtcttcc ttacggtccg tatctcggac aaaacgataa
     7021 ggagagttct tgtggtcttg ttcaactgtc catagatgga gaatttcctt agtcgctgcg
     7081 acaaaagtct catcaaactg actagtctcg ccagtttctt tccagaggag ataagccaac
     7141 tgcaaaggat agcaaagcga gtccacctca tacttgcgtt cccaaatcca gccattaagg
     7201 tcggtgtggt cggtctcgtg gtgccccttc cagttttcct ctatgttgaa ggaattggca
     7261 taaggatcct tgagtaccaa ggtcatctga cgtttgacca aacctgcaat ggtctgacgc
     7321 aggagggcat ctcttttagc tacatgcagg tagggtctga gttgggctgt cgaatcccga
     7381 agccacatag caggaatatc cccagtcaag acaaaagttg aaccatcttc taagatttca
     7441 accgtattgt ccaaggtatc ggtgtagcaa cgctcgaaaa catccaccca ctctggatgg
     7501 tccttagccc gctctgctac ttcatctagc cattctctaa caatttcttt cggataaatc
     7561 atcgtgcaat tccctctttc aaacaagttt catgttcagt atatagcttt tgagacagaa
     7621 aatacataca caaatgatag tcatttttct acaaaatagt tatttttgaa actccttttc
     7681 taaaggccct ctttttctga tataatgtag aaaaacagct aaaggaaaga ctatgaaacc
     7741 actacttgaa accatcgata cccgctttgg tactgctagc aagcatgcct tctcttgggg
     7801 aaataccctg ccatacacag gcgtgccttt tgggatgaat tactttgtgc cccagaccag
     7861 tgaccaggat ggatcttggt tttttgatcc gcatctgcct atctttcagg ggattcgatt
     7921 aactcaccag cccagtcctt ggattgggga ctactcttgg ctccttctga cacctgtcac
     7981 cagtcaactg gggggagaca gcctctttca ccgccagtct tcttatgata tagataaagc
     8041 ttgcttccag cctcactatt tgaagctctt ttctctgcgt tatcagattg aaacccagct
     8101 cacaccaact tgctatggtg cttctattcg tttgaatcaa aagcaaggca aagccctctc
     8161 cctctatctt cacgcagcag atgaactgac agtagagcaa gtagataagc ggactcttgc
     8221 cctgcgacaa gaaggtaaaa ctgaaactaa caaaaattcg ctaacgatgt tcactgccct
     8281 gcaaatgaac acggatattc ttgctatcag ccaagaagct ggagactggc gaattgactt
     8341 agtaagtagt caaaccgaga tgcaactagc cacttctttc atctctcctt ctcaagctct
     8401 aatcaatcta cctcaagaag attttgatag ctgtaaatca agtgcccaag cggattggga
     8461 aaatctcctc catcgttttg acattataga gacaggagag gctgaccgaa ccttctttga
     8521 ccactgcctc tacagactct tcctcttccc acagactttt tatgaggttg atgagtcagg
     8581 gcaagccatc cacatggatc tggctactgg tactgtcaag cctggtgtcc tctttagcaa
     8641 caatggtttc tgggatacct tccgcaccac cttccccctc tttgccctta tcataccgga
     8701 gcactatcaa cgctttttag aaggtttcct caatagctac cgcgatactg gtttccttcc
     8761 aaaatggctg gctccagatg aacggggtat gatgccaggt acacttttag acggtattat
     8821 cgcagatagc gcctgcaagg acatggcccc tgacctagaa ggagaactct tccaagccat
     8881 gctcgaaaca gccagcaaag ccgaccctct cggcatcaat ggccgccacg gactagccca
     8941 ataccaagaa ctaggttacc tctctaccga ccaccacgaa agtgttagcc atactctaga
     9001 ctatgcctat agtgactttt gtatcgccag ctgtgccaaa aaactagaga acatagaaat
     9061 cgctgaaacc tacaaggctg cttcacaaaa ttaccgccag ctatttgacg ctgagacagg
     9121 ttacatgcga gcacgagaca atcaaggaaa ctttcaccct gacttctctc cttatagttg
     9181 ggggcgagac tacgctgaat gctctgccat tcaagctact ttaggcgttc tccacgacat
     9241 ccctggctta atccaactga tgggtggaaa agaaaccttt agcaactatc ttttgaaaac
     9301 ctgtcaagat gctcccctct ttgaaacaac aggctatggt tacgaaattc acgaaatgag
     9361 cgagatggct actgctcctt ttggacaaat agccatttcc aaccagccta gtttccacat
     9421 tccttatctc ttccgttaca gcgattaccc tgactacact gcccttctta tcaagacgct
     9481 ccgtcagaaa gcttttcacc caagttggga agcctatcct ggagatgaag acaatggtag
     9541 tctctctgct tggtacatct ggtcagctct cggattttat ccaacctgtc caggaaaacc
     9601 aagctatgac ctcggaatcc ctctctttga ccatctacga gtctacctcg ctaaagaaga
     9661 taaatggctg gatatccata ctaaacaaaa ccacaaccat tttaactttg tcaaagaatg
     9721 ccgactggac aaaacactcg tatcaactat tcaacaccaa gacctcttaa aagctgaaca
     9781 actaactttc accctcagct ggttaccaag tcactaataa ccaaaagaac ctttgcatcg
     9841 cgcaaaggtt cttcttttat gaaacttgga cttgaagttg atccacaagc tgaccatcca
     9901 ccgttaggtt cagatagaaa tccaaggttt tatctcctgc gaaatacagg gttggtagat
     9961 gcaaatcttt tttgctttcc cctgcttgga attgaaggac ataaatctcg tcctgatagg
    10021 cgacaccatg gacacctgtc cccggttgaa tcgaaatctt agcttctaaa ggaccactac
    10081 attctctgcg cttaactgta aaataggcat tttctccctt tgccacagct aggctttttt
    10141 ctgcaaatgc tagttcctga acaacttctt tttttgataa ttcaggagtt ttataaaggg
    10201 aaatcttggt caatacagga atagattgtg cctcggtaat catcacgcgc accttctgtg
    10261 cctctactag cggacctcgc aagaggcgct tatgaccaac tgtgaagccc ctgccaaatt
    10321 cctgccagac accatccacc tctacttgca catgaaaagc agcgattcgt tgccctagct
    10381 tcaaatcttc tcttaactca attacatcaa aagttttagg agaacctaag tcgagttcta
    10441 actggatggg caagtctgca tcgtttgccc aagagctggt ctcaaggccg tctgtcaaat
    10501 ggcgacaagc aaagtctgcg gaaagagctg gaccagatac ctcagctccc agagccaaat
    10561 cttctttata gagctcattg cgataggtcg caaattcata aagtcgttca atatcctttg
    10621 catcaaagag cccagcttga ttcggcggaa tattaagcaa gagtggagtt cctcgcccta
    10681 ctgagtgaaa gtagatttcg accaactcct cgagagactt aggatcctga tcctcatggt
    10741 agaaccagcc tggacggatg gaaacatctg cctctccgat tgaaaaaatc gtgcccgagg
    10801 gatccccgtg ctgaagatag tccagctctg cttctgttcc tagtttatca ggattcacct
    10861 tttgccacag tggatcacct gcataccctc gttcattgcc aatccagcgg atactggtgc
    10921 cttctgttga aaaaatcaaa caatcgccct gcaagtcacg aatggtttca aaccattttt
    10981 caaattcata attgacctgc tgggcccctt cccctctagc accatccatc caaacctcag
    11041 cgaacttacc agcattccca tagttaggat ttgataagat ttccttcaac tgagccagat
    11101 aataggcatt gtagtccgct tctcggtcca catgatagag gggactatgg gcatcccacg
    11161 gtgacaggta gacccccata tccatatcaa actctgtggc agcttgggat acttcaagga
    11221 gcaagtcgcc ctttcctctc ctccaaggac tgaccttaac cgaataatct gtgtgagctg
    11281 tcggataaag gacaaagcca tcgtggtgct tgaccaccaa aatcaacttt ttgaagcccg
    11341 tttccttgag cacacgaacc cactcacgcg catccaactg actcgggtta aagcgctcag
    11401 gatcctcctg acctgttccc cattcctgat tataaaaagt attaggtcca aaatggataa
    11461 aggctgctag ttcatctccc agataagcta gctgagtctg acttggtaac ggtccatgcg
    11521 gtttgatttt cttcatcgtt atatatctcc ttcttttgca acttctcttg ttcacaaggt
    11581 tatccacagg ttgtggataa taaaccatga tctaacagcc agctctttcc aactccaact
    11641 ggtaggctca ggatttttct cctcaatatt ccctcttcaa acagctctgt catatggttc
    11701 tgctaacacc tctcagaatg ctactctcca taattattct caggcttctt tcaggtcatt
    11761 gtgtgaagac cattcactct ccagactttt ccacagattg tgaataagtg attattctaa
    11821 actatcacct cgtcgactat aacaaaaaat aaaaagaggg tcaataagat aattatctct
    11881 tcctaaatac tcagaaaaga ttctataatt tgtacaattg aacaagaaat gcttctccaa
    11941 aatctatctt caaaagaatg ttgcatcttt ttatcctttc acacaaacat ttctctttat
    12001 acagatccaa gtgataacca gatgataatt ggacactttt tggttatttg tgtatttttt
    12061 gaaaaatttt ttaaaaaaat tttatatcct ctttaataga agtttatgaa tttgtatata
    12121 tgtattccat cctatgttgt gtataataac ataaaattgt gctaaatatc ataatttata
    12181 ttattttccg agaaattata gccattgaca ttacctagga attgcgttat aacatacatg
    12241 taagcggtac ccaaaatggt gccaagtcaa aatttttaag gaggaaaata catgtcttca
    12301 catccaattc aggtcttctc agaaattggg aaactgaaaa aagttatgtt gcaccgtcca
    12361 ggcaaggagt tagaaaactt gttgccggac tatcttgaaa ggcttctttt tgatgatatt
    12421 cctttcttgg aagatgctca aaaagaacat gatgcatttg cccaagctct tcgcgatgaa
    12481 ggaattgagg ttctctacct agaacaactc gctgctgaat cattgacctc tccagaaatc
    12541 cgcgatcaat ttatcgagga atacttagac gaagccaaca tccgtgatcg tcaaactaag
    12601 gttgctattc gtgaattgct tcacggcatc aaggacaacc aagaattggt tgaaaaaaca
    12661 atggctggga ttcaaaaagt tgaattgcca gaaattcctg acgaagctaa agatctaact
    12721 gacttagttg aatcagatta tccatttgca attgacccga tgccaaacct ctatttcact
    12781 cgcgacccat ttgcaacaat tggaaacgcc gtatcgctta accacatgtt tgcagacact
    12841 cgtaaccgtg aaacactcta cggtaagtat atcttcaaat accacccaat ctatggcgga
    12901 aaagtggatt tggtctacaa ccgtgaagaa gatacgcgta tcgaaggtgg agacgagcta
    12961 gttctttcta aagacgtcct tgcagtaggt atctctcaac gtacagacgc agcttctatc
    13021 gaaaaacttt tggtcaacat cttcaagaaa aatgttggct tcaagaaagt tttggccttt
    13081 gaatttgcta acaaccgtaa attcatgcac ttggatactg tcttcactat ggtagactat
    13141 gacaagttca ctattcaccc agaaatcgaa ggcgaccttc acgtttactc agttacttac
    13201 gaaaacgaaa aacttaaaat tgttgaagag aaaggtgact tagctgaact tcttgctcaa
    13261 aaccttggtg tagaaaaagt tcatttgatt cgttgcggtg gtggcaatat cgtagcagct
    13321 gcgcgtgaac aatggaacga cggttctaac actttgacca tcgcacctgg tgtggtagtt
    13381 gtttatgacc gcaataccgt gaccaataag attttggaag aatacgggct tcgcttgatt
    13441 aagattcgcg gaagtgaatt ggttcggggc cgtggtggac ctcgttgtat gtctatgcca
    13501 tttgaacgtg aagaagtgta atcgctgttc ggtattcgtc aatagaaaat gtaaaaaata
    13561 gaaagaggaa ataataaaat gacaaattca gtattccaag gacgcagctt cttagcagaa
    13621 aaagacttta cccgtgcaga gttagaatac cttattggtc tttcagctca cttgaaagat
    13681 ttgaaaaaac gcaatattca acaccactac cttgctggca agaatatcgc tctcctattt
    13741 gaaaaaacat ctactcgtac tcgtgcagcc tttacaactg cggctatcga ccttggtgct
    13801 cacccagaat acctcggagc aaatgatatt cagttgggta aaaaagaatc tactgaagat
    13861 actgctaaag tattgggacg tatgtttgac gggattgaat tccgcggatt cagccaacgt
    13921 atggttgaag aattggcaga attctcaggc gttccagtat ggaacggtct aactgacgaa
    13981 tggcacccaa ctcaaatgct cgctgactac ttgactgttc aagaaaactt cggtcgcttg
    14041 gaaggcttga cattggtata ctgtggtgat ggacgtaaca atgttgccaa cagcttgctc
    14101 gtaacaggtg ctatccttgg tgtcaatgtt cacatcttct caccaaaaga actcttccca
    14161 gaaaaagaaa tcgttgaatt ggcagaagga tttgctaaag aaagtggcgc acatgttctc
    14221 atcactgaag atgctgatga agcagttaaa gatgcagacg ttctttacac agacgtttgg
    14281 gtatcaatgg gtgaagaaga caaattcgca gaacgtgtag ctcttcttaa accttaccaa
    14341 gtcaatatgg acttagttaa aaaagcaggc aatgaaaact tgatcttcct acactgcttg
    14401 ccagcattcc acgatactca cactgtttat ggtaaagacg ttgctgaaaa atttggtgta
    14461 gaagaaatgg aagtaacaga cgaagtcttc cgcagcaagt acgctcgcca cttcgatcaa
    14521 gcagaaaacc gtatgcacac tatcaaagct gttatggctg ctacacttgg taacctttat
    14581 attcctaaag tataatttta gataataaac cgtctaccaa cagctatgag ggctgcgact
    14641 aatagcttta gtccggtcct cttttatgta atggtaatct attatttctt ataaaatatg
    14701 tgaaaaatca ttaaattgaa atctaaacgc attctattga gtgtgataaa ggagaattta
    14761 tggcaaatcg taaaattgta gtagctttgg gaggaaatgc gattctttct tctgacccat
    14821 cagcaaaggc tcaacaagaa gctttagttg aaacagctaa gcatcttgta aaattgataa
    14881 aaaatggaga tgatctgatt atcactcacg gtaatggacc tcaagttggg aatctcttgc
    14941 tccaacattt ggcatcagac tctgaaaaga accctgcctt cccactcgac tcacttgtcg
    15001 ctatgacaga aggtagcatc ggtttctggt tgaaaaatgc tttgcaaaat gctctcttgg
    15061 atgaaggcat cgaaaaaaat gttgcctctg ttgtaacgca agttgtcgta gataaaaatg
    15121 atccagcttt tgttaacttg agtaaaccaa tcggtccttt ctattcagaa gaagaagcaa
    15181 aagcagaagc cgaaaagagc ggagcgactt tcaaggaaga tgctggccgt ggctggcgta
    15241 aggtcgttgc ctcaccaaaa cctgttgaca tcaaagaaat tgaaaccatc cgtactcttt
    15301 taaataatgg tcaagtcgtc gtagctgcag gtggtggcgg tattcccgtc gtcaaagaaa
    15361 acaatggaca tttgactggt gtcgaagcgg ttattgataa agacttcgct tcccaacgtt
    15421 tggcagaatt ggttgatgca gacctcttca tcgttttgac aggtgtagat tatgtatttg
    15481 ttaactacaa caagccaaac caggaaaaat tggaacatgt gaatgttgcc cagctagaag
    15541 aatatatcaa acaagatcag tttgcaccag gtagcatgct tccaaaagta gaagcagcta
    15601 tcgcttttgt caatggtcgt ccagaaggaa aagcagttat tacttccctt gaaaatctag
    15661 gcgccttgat tgaatctgaa agcggaacaa ttattgaaaa aggataagtt gttttactaa
    15721 taagatgtat tctatttcta gtatctttat atcaaattag aaattattct tgaaaacatg
    15781 tacaatattt caaaagatat tagtttttta gactttaata tggtaaaaca aatataaata
    15841 gaaagcgttt tcttaaatgt ttatttaaga aagtagttgg ttttttacac tttgttagac
    15901 atcaggagga aaaacaaatg agtgaaaaag ctaaaaaagg gtttaagatg ccttcatctt
    15961 acaccgtatt attgataatc attgctatta tggcagtact aacttggttt atccctgcgg
    16021 gggcctttat agaaggtatt tacgagactc agcctcaaaa tccacaaggg atttgggatg
    16081 tcctcatggc accgattcgg gctatgctag gtactcatcc agaggaaggt tcgctcatta
    16141 aagaaacgag cgcagcgatt gatgtagcct tcttcatcct tatggttggt ggtttccttg
    16201 gcattgtcaa caaaactggt gctcttgacg tagggattgc ctctatcgtg aagaagtata
    16261 agggccgcga aaaaatgtta attttggtac taatgccttt gtttgccctc ggtggtacaa
    16321 cttatggtat gggtgaagaa acaatggcct tctatccact ccttgtgcca gttatgatgg
    16381 ccgttggttt tgatagcctg actggtgttg caattatttt gctcggttct caaatcggct
    16441 gtttggcatc tactctgaat ccatttgcga caggtattgc ttcagcgact gcgggagttg
    16501 gtacagggga cggtatcgta cttcgtctga ttttctgggt taccttgact gctcttagta
    16561 cttggtttgt ttaccgttat gcggataaga ttcaaaaaga tccgactaag tcactggttt
    16621 atagtactcg caaagaagat ttgaaacact ttaacgtaga agaatcttca tctgtagaat
    16681 ctacacttag cagcaaacaa aaatcagttc tcttcttatt tgtgttgaca ttcatcttga
    16741 tggtattgag cttcattcca tggacagacc ttggcgttac catttttgat gactttaatg
    16801 cttggttgac tggtcttcca gttattggta atattgtcgg ttcatctact tctgcactag
    16861 gtacttggta cttcccagaa ggcgcaatgc tctttgcctt tatgggtatc ctgattggtg
    16921 ttatttatgg tcttaaagaa gataagatta tctcttcctt catgaatggt gctgctgact
    16981 tgctcagtgt tgccttgatc gtagcgattg ctcgtggtat tcaagttatc atgaacgacg
    17041 gtatgattac cgatacaatc ctcaactggg gtaaagaagg cttgagcgat ctatcttcac
    17101 aagtctttat cgttgtaact tatatcttct atctacctat gtcattcttg atcccatctt
    17161 catctggtct tgccagcgca actatgggta tcatggctcc acttggagaa tttgtaaatg
    17221 tccgtcctag cttgattatc actgcttacc aatctgcttc aggtgtcttg aacttgattg
    17281 caccaacatc tggtattgtg atgggagctc ttgcacttgg acgtatcaac attggtactt
    17341 ggtggaaatt catgggcaaa ctcgtagtcg ctattattgt agtgaccatc gcccttcttc
    17401 tccttggaac cttccttcca ttcctataaa atagtgagtg aggtgattcc atgaaaatag
    17461 atataacaaa tcaagttaaa gatgaatttc ttatatcatt aaaaaccttg atttcctatc
    17521 cttcagtact caatgaagga gaaaatggaa caccttttgg acaagcaatc caagatgtcc
    17581 tagaaaaaac tttagagatt tgtcaagaca taggtttcac tacctatctt gaccctaaag
    17641 gttattacgg atatgcagaa atcggtcagg gagcagagct tctggccatt ctctgtcatt
    17701 tggatgttgt tccatcaggt gatgaagcag attggcagac accgccattt gaagcaacta
    17761 tcaaagacgg ctgggtattc ggacgtggtg tccaagatga taaaggccct tcgctcgcag
    17821 ctctttatgc agtaaaaagc ttgctggacc aaggtattca gttcaaaaag cgcgtacgct
    17881 ttatctttgg taccgatgag gaaaccctct ggcgctgcat ggcacgctac aataccatcg
    17941 aagaacaggc cagcatgggc tttgcacctg actcatcttt tcctctgacc tatgctgaaa
    18001 aagggcttct acaggtcaaa cttcatggcc ctggatcgga tcaactagag cttgaagtag
    18061 gaggcgcctt taacgttgta ccagacaagg ccaactacca aggtcccctc tatgaacagg
    18121 tttgtaacga tctcaaagaa gctggttatg attaccaatc cactgaacaa accgtaacgg
    18181 ttctcggagt gccaaagcat gctaaggatg ctagtcaagg tatcaatgct gtcatccgac
    18241 tagctaccat tcttgctcct ctccaagaac accctgctct cagctttctt gcaacacaag
    18301 caggtcaaga cggcacagga agacaaatct ttggtgatat agcagatgaa ccttctggtc
    18361 acctatcctt taatgtcgca ggtctcatga tcaatcatga acgttctgaa atccatattg
    18421 acattcggac tcctgtctta gctgataagg aagaactagt agagttgctt agaagatgtg
    18481 cacaaaacta ccaactccgc tacgaagagt ttgactatct agcgcctcta tacgtcgcaa
    18541 aagacagtaa actcgttagc acactgatgc aaatctacca agaaaagact ggcgataaca
    18601 gtcctgctat ttcatccggt ggtgccactt ttgctcgcac catgccaaat tgtgtagcct
    18661 tcggcgcctt attcccagga gcaaagcaga cagaacatca ggcaaatgaa tgtgccgttc
    18721 tagaagattt gtaccgtgct atggatattt atgccgaagc cgtctatcga cttgcaactt
    18781 aatcaggcaa ctgtttctac caaaaaaaat cgaccgatta atgaactgca ccccaaaagt
    18841 tagacagaat aaatctaact tttggggtgt tttattatga aattgagtta tgaagataaa
    18901 gttcagatct atgaactaag aaagcaagga caaagcttca aacagctttc aaaaagattt
    18961 ggtgtggatg tttct
//
LOCUS       DAVAGB010000040        18226 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVAGB010000040 DAVAGB010000000
VERSION     DAVAGB010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18226
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.040"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(32..277)
                     /locus_tag="VQO19_001577"
     CDS             complement(32..277)
                     /locus_tag="VQO19_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET1349811.1"
                     /translation="MEQSPKKKKGTTLEHIILLRGVTPNGKNAIPKMSYLVDILTEAD
                     FQQVRTYIQSGNIILESNLALEEIREQVHTLLDFLQN"
     gene            complement(292..1464)
                     /locus_tag="VQO19_001578"
     CDS             complement(292..1464)
                     /locus_tag="VQO19_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET1349812.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITELEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSNPI"
     gene            complement(1523..2368)
                     /locus_tag="VQO19_001579"
     CDS             complement(1523..2368)
                     /locus_tag="VQO19_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET1349813.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            2493..3050
                     /locus_tag="VQO19_001580"
     CDS             2493..3050
                     /locus_tag="VQO19_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET1349814.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            3069..3536
                     /locus_tag="VQO19_001581"
     CDS             3069..3536
                     /locus_tag="VQO19_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HET1349815.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            3625..4254
                     /gene="upp"
                     /locus_tag="VQO19_001582"
     CDS             3625..4254
                     /gene="upp"
                     /locus_tag="VQO19_001582"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HET1349816.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            4428..5018
                     /gene="clpP"
                     /locus_tag="VQO19_001583"
     CDS             4428..5018
                     /gene="clpP"
                     /locus_tag="VQO19_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HET1349817.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            5097..5345
                     /locus_tag="VQO19_001584"
     CDS             5097..5345
                     /locus_tag="VQO19_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HET1349818.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            5447..6607
                     /locus_tag="VQO19_001585"
     CDS             5447..6607
                     /locus_tag="VQO19_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET1349819.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            6875..7744
                     /locus_tag="VQO19_001586"
     CDS             6875..7744
                     /locus_tag="VQO19_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET1349820.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            7748..8704
                     /locus_tag="VQO19_001587"
     CDS             7748..8704
                     /locus_tag="VQO19_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET1349821.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            8704..9468
                     /locus_tag="VQO19_001588"
     CDS             8704..9468
                     /locus_tag="VQO19_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1349822.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKDKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            9468..10178
                     /locus_tag="VQO19_001589"
     CDS             9468..10178
                     /locus_tag="VQO19_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1349823.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            10485..11141
                     /locus_tag="VQO19_001590"
     CDS             10485..11141
                     /locus_tag="VQO19_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET1349824.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            11249..12344
                     /gene="prfB"
                     /locus_tag="VQO19_001591"
     CDS             join(11249..11320,11322..12344)
                     /gene="prfB"
                     /locus_tag="VQO19_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HET1349825.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            12362..13054
                     /gene="ftsE"
                     /locus_tag="VQO19_001592"
     CDS             12362..13054
                     /gene="ftsE"
                     /locus_tag="VQO19_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HET1349826.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            13047..13973
                     /locus_tag="VQO19_001593"
     CDS             13047..13973
                     /locus_tag="VQO19_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET1349827.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLRI"
     gene            14259..16439
                     /locus_tag="VQO19_001594"
     CDS             14259..16439
                     /locus_tag="VQO19_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET1349828.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     NAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            16491..17306
                     /locus_tag="VQO19_001595"
     CDS             16491..17306
                     /locus_tag="VQO19_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET1349829.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAVLNWK"
     gene            17512..>18226
                     /locus_tag="VQO19_001596"
     CDS             17512..>18226
                     /locus_tag="VQO19_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000465984.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET1349830.1"
                     /translation="MFFQDRKIKYSIRKLSVATVSLAIGFLFAPAALGVAQVAQADEL
                     STTEQVENKAENQVSVVSFATEQEESETTYVDTTNKVTWTFAGYDKEKIVVGKGRQTF
                     LGSWVPTPNPEYVFKSSKAGVPLPQSILGMLPKDEASYKVGDTIVAKQPAVESVVEEE
                     KDYVWTFKGYDQKNATYNGKRVTFTGIWEVTPRPHHVSYTFVSVTSGVDLPKFIQKKA
                     PKDGSTYFNRTRVFAEEPTT"
BASE COUNT         5534 a         3334 c         3953 g         5405 t
ORIGIN      
        1 ttgctggcat tatcaatcat gaactaggat tttagttttg caggaagtct aatagagtat
       61 gaacctgttc tcgtatttct tcgagagcta agttactttc aagaataata tttccacttt
      121 gaatataagt tcgaacttgt tgaaaatcag cttctgtcaa gatatctact agataagaca
      181 ttttagggat agcatttttt ccattaggag tgactcccct tagcaagata atatgttcca
      241 aagtagttcc tttctttttt ttgggggatt gttccattta gtaatgtata tttagattgg
      301 atttgatccc gccacccagc cggtacagag agcagaagtg atgttaaagc cacccgtgtg
      361 ggcattgata tccataactt cgcctgcaaa gtggaggcca ggtaccagct tactttcaag
      421 ggttttagga ttgatttcct tgagactgac tccacccttg gtaacaaagg actttgcaag
      481 ggacattttt ccagttacag gaattttaag ttctttaatg gactggacaa gttgttctcg
      541 ttccttttca gtcagctgtt tgactttttc aggatatcct tgtacaaaaa attcggccaa
      601 gcgttctggt aacaaggttt ttaaagcgtt tttcaaggat ttttcccgat tttcttctag
      661 aaatgtaacc aagtccttct cagaaagttg aggcaaaaca tcgagtgaga gaacctcccc
      721 acctttgaca aagctagaca tgcgtagggc agcaggacct gacaaaccaa agtgggtaaa
      781 gagtaaatca tgagtgatga catgcttacc ataacttagg gtcacatcgt ccaaagaaat
      841 cccttgtaag gctttatgtg gaaaatctgt taataaagga ctttcagcag cctcaagctc
      901 ggtgatggta tgcttaaaat ggcgagcaat ctcgtgacca aaaccagtcg aaccagtcga
      961 aggataagac ttaccacctg ttgtgacaat gagtttctca caagtgaagg tttgatccgc
     1021 tgacttaagg acaaactggt catctacttt tttaacagaa acgatttcta tttgagtagc
     1081 aacttgacca cctagttcag tgattttctt ttccaaagct tcgataatag tccgagactt
     1141 gtcactggct ggaaagacgc gtccgtggtc ttcgacctta agtttaacac cattttctgt
     1201 aaaaaagttg atgatgtcat gattatcgaa ctgggagaaa acactgtaaa gaaagcgtcc
     1261 gtttccagga attccagcta gcaggttgtc taagctacca ttgttggtca cattgcaacg
     1321 tcccccacca gtcccagcta atttttttcc aagtttccga tttttttcga tgaggagggt
     1381 tttctgtcca taaaagctac tggaaatcgt agccatcata ccagcaggtc ccccaccgat
     1441 gacaatagta tcaaaatgtt tcatagctct attgtaccac aaaaaaacaa gagatgatgg
     1501 tcacctcttg tcaagaatgc aattaatcaa tttcatagcc catcagcaaa ccgccctctt
     1561 ctgcatagaa actgcagaga ccagaggttg gtagaatttt aatatccgct tgtgggaagg
     1621 tttcacggat tcgctctgag agctgttgac aacatttttc gttattgcgt tgggccatga
     1681 caatacggcc accagcatat ccagctttta ctaactcatc ataggcagct tgaactgatt
     1741 tctttgatcc ccttgctttt tgtagcaatt cgagagttcc agtttcacta gcttttccga
     1801 ccatacgaat gttgagaagg ccaacgaccg taccgataag cttgctcaaa cggccgttct
     1861 tcaccaagtt atcgactttg gctaggacaa agagcaactt agttttttct tgataggcgg
     1921 tgatagcttc aaccacttct tcaaaagaca agccctggtc aatcaagtca ttcaattttt
     1981 ctacgagtag gtcaacttca ccaccagcag ataaactatc aatcacatga atcttagtgt
     2041 caggatggtc ttccagataa atattctttg ctagttgagc actattgtga ctgccagaaa
     2101 gggtacctgt gatggttact aggaaaatgt ttttggcacc ttcaaatgct cgcaaatagt
     2161 catctgggct tggacaagcc gattttgaag cttctgcagt tgcatacatg gtttccatca
     2221 tttggtcaat atcgagactg gcgtcatcaa caaagacctg atcagctact tgaatggtta
     2281 aggggacact tacaaaggtt gtgttaatag ctggtgttgg cagttgacga taatcacaac
     2341 cagagtcagc aataatcttc caagtcatag aaattctcca tctttgtcag ttatacattg
     2401 acaaaggttc tgtctttttt tacaattata tcatgaaaac ccttgaaaca aaagcatcat
     2461 ccgtctgttg tgacaagtag aaagaaaatg ttatgtctga acgtagaatc tctgaaaagt
     2521 ctcttgaaaa tctcagaaaa tcaaaccaag aatccaattt attaaccaga gaagccattg
     2581 aaacagccct cttgcaactc ttggaaaaaa aggaactgac caagattagt atttctgaat
     2641 tggtcaaacg tgcaggtgtt tcgcgtgcgg ccttttatcg caattatgac tccaaagagg
     2701 aaattttaga gagcgtcttt aaacgaactg tccacaatat tatggaacag ctgcatcatt
     2761 acgatttaaa gacagacctt tatttggttt gggttcacct tttccgggag gccagaaagg
     2821 aagctagagt gattcaattg gccttggatt accatctgga aaaaatcttt gtccaagcca
     2881 tgcaggaatt tctagaaaaa taccatggga aatcaaaagg tgtcagctct tatcttcatt
     2941 ccttctggag ctcagccatc gtctctgtcc ttctaaaatg gatcaaggat ggcatgaagg
     3001 taccagctga aaagattgca gatttaggtt taccattttt taaaaaatag agaaaaagga
     3061 gaaaagagat gactgaaaaa agactggcct gggatgagta ttttgcagcc caagccctac
     3121 taattgcgaa tcgttccact tgtaaacgtg ctaaagtggg cgcgattctg gtaaaagata
     3181 ataaggttat ttccactggt tacaatggtt cggtgtcagg gactgagcat tgtattgatc
     3241 acgaatgttt ggtcattgaa ggccactgtg ttcgcaccct tcacgctgag gtcaatgcta
     3301 tccttcaagg tgctgagcgt ggtgttccca aaggctttac agcctatgta acccattttc
     3361 cttgtctcaa ctgtacaaaa caattgcttc aggtcggctg caagcgtgtg gtttatatca
     3421 accagtaccg aatggacgac tacgcccaat acctttatca agaaaaaggg acagaattga
     3481 cccatttacc acttgagaca gtacagacag ctcttaaaga ggctgatcta atgtaaaaat
     3541 tatcaaaaat aaatggttta gaaagatttt taaaccgttt tttggtataa taagaagaat
     3601 aaattgaaag aaggaattcc aaaaatggga aaaattgaag ttattaatca cccactgatt
     3661 caacacaaat tgtcaatctt gcgtcgtaca gatacttcta caaaagcttt tcgtgagcta
     3721 gtagatgaga ttgcaatgtt gatggggtat gaagtacttc gtgatcttcc actagaagat
     3781 gtggaaatcg aaacaccaat tacaaaaaca gttcaaaaac aattggcagg taagaaattg
     3841 gccatcgtcc caatcttgcg tgcaggtatc gggatggttg atggtctctt gagcttggtt
     3901 ccagctgcta aagttggcca catcggtatg taccgtgatg aagaaacact tcaaccagtt
     3961 gaatacttgg tgaaattgcc tgaggacatt gaccaacgtc aaatttttgt agtagaccca
     4021 atgttggcaa caggtggctc agcaatcttg gctgttgatt ctcttaaaaa acgtggcgca
     4081 tcaaatatca aatttgtctg ccttgtatct gctccagagg gtgtaaaagc ccttcaagaa
     4141 gctcatccag atgtagaaat ctttacagca gccttggatg aacgtttgaa cgaacacggt
     4201 tatatcgttc caggtcttgg agatgctgga gaccgcttgt tcggtacaaa ataagatcga
     4261 aaagaagaat gacttggaaa agtatttcca gtcacgaaag gaggttgggt ttttgtttct
     4321 gtctaatgaa agcagagcaa aaatttgacc ttttttgacc aagatattat aatagtctta
     4381 tcttcagtca tttgaccaac aaaattaaaa ctcaaaagga gaaatgaatg attcctgtag
     4441 ttattgaaca aacaagccgt ggagaacgtt cttacgatat ttactcacgt cttctcaaag
     4501 accgcatcat tatgctgaca ggtccggttg aagacaatat ggctaactct gttattgccc
     4561 aattgctttt cttggatgcc caagatagta caaaagatat ttacctttat gtcaatacac
     4621 caggtggttc tgtttcagct ggtttggcaa tcgtagatac catgaacttt atcaaggcag
     4681 atgtccaaac cattgttatg ggaatggctg catctatggg gactgtcatc gcatcaagtg
     4741 gagcaaaagg caaacgtttc atgcttccaa atgctgaata catgattcac caaccaatgg
     4801 gcggtacagg tggtggtacc caacaaactg atatggctat cgctgcagaa cacttgctca
     4861 aaactcgtaa taccttggaa aaaatcttgg ctgaaaattc aggtcagtca atggaaaaag
     4921 tccatgcaga tgcagaacgt gataactgga tgagcgccca ggaaacactt gaatatggct
     4981 ttattgatga aattatggcc aacaattcat tgaactaatg atgatagaag gcaaactcga
     5041 ctgggtttgc tttttttggt ataataggga gagatttctt agaaagagga tttatcatgt
     5101 ttgaaaaagt caatcgctct ggcttgatta tctatcttta ctataatcgt gatgccaaaa
     5161 aactgcagga ttatggagat attacctatc attccaagaa acatcgttac ttacaactct
     5221 atgttccaac tcaagaagtg gagcaattgg tcggacgctt gagcaaggaa aaatttatta
     5281 aaaaagttag ggtttgtcat atccaagagt tggaaacacc ctttgtgggc aatctttatc
     5341 gataggaaaa cgttatcatc gaaaaaagct caaggaaaac attgacaatt ttctgataat
     5401 tcggtatatt cttaacagac tatttaagaa ataaggagac aaaaagatga agaaaaaatt
     5461 tgccctatcg tttgtggcgc ttgcaagtgt agcacttctt gcagcctgtg gagaagtgaa
     5521 gtctggagca gtcaacactg ctggtaactc agtagaggaa aagacaatta aaatcgggtt
     5581 taactttgaa gaatcaggtt ctttagctgc atacggaaca gctgaacaaa aaggtgccca
     5641 attggctgtt gatgaaatca atgccgcagg tggtatcgat ggaaaacaaa tcgaagtagt
     5701 cgataaagat aataagtctg aaacagctga ggctgcttca gttacaacta accttgtaac
     5761 ccaatctaaa gtatcagcag tcgtaggacc tgcgacatct ggtgcgactg cagctgcggt
     5821 agcgaacgct acaaaagcag gtgttccatt gatctcacca agtgcgactc aagatggatt
     5881 gactaaaggt caagattacc tctttattgg aactttccaa gatagcttcc aaggaaaaat
     5941 tatctcaaac tatgtttctg aaaaattaaa tgctaagaaa gttgttcttt acactgacaa
     6001 tgccagtgac tatgctaaag ggattgccaa atctttccgc gagtcataca agggtgaaat
     6061 cgttgcagat gaaactttcg tagcaggtga cacagacttc caagcagccc ttacaaaaat
     6121 gaaagggaaa gactttgatg ctatcgttgt tcctggttac tataatgagg ctggtaagat
     6181 tgtaaaccaa gcgcgtggca tgggaattga caaaccaatc gttggtggtg atggattcaa
     6241 cggtgaggag tttgtacaac aagcaactgc tgaaaaagca tcaaacatct actttatctc
     6301 aggcttctca actactgtag aagtttcagc taaagctaaa gccttccttg acgcttaccg
     6361 tgctaagtac aatgaagagc cttcaacatt tgcagccttg gcttatgatt cagttcacct
     6421 tgtagcaaac gcagcaaaag gtgctaaaaa ttcaggtgaa atcaaggata accttgctaa
     6481 aacaaaagat tttgaaggtg taactggtca aacaagcttc gatgcagacc acaacacagt
     6541 caaaactgct tacatgatga ccatgaacaa tggtaaagtt gaagcagcag aagttgtaaa
     6601 accataatag aaaaatgttg aaatagggaa tgagcctttg actcactccc tgtttcgata
     6661 tttaatactc ttcgaaaatc tcttcaaact gcgtcaacgt cgccttggat tatatatgtg
     6721 actgacttcg tcagtcttat ctacaacctc aaagcagtgc tttgagcaac ctgcggctag
     6781 tttcctagtt tgctctttga ttttcattga gtataagaac ctatcaaaaa gtgagggaaa
     6841 accctcggaa ttataaatag aaagagtgaa tcttatgctc caacaactcg taaatggttt
     6901 gattctaggt agtgtttacg cgctgttagc cctaggatat accatggttt acggaattat
     6961 caagctcatc aacttcgccc atggtgatat ttatatgatg ggagccttta tcggttattt
     7021 cttgatcaat tctttccaaa tgaatttctt tgtagcgctt attgtagcta tgctagcgac
     7081 agctattctt ggtgtcgtga ttgagtttct tgcttaccga cctttgcgcc actctactcg
     7141 tattgctgtt ttgattacgg ctattggggt ttctttccta ttggagtatg gaatggtcta
     7201 tctggttggt gccaataccc gtgccttccc tcaagcgatt caaacagttc gatatgattt
     7261 gggaccaatt agcttaacaa atgtgcagtt aatgattttg gctatttcct tgattttgat
     7321 gattttgtta caagtcattg tccaaaagac taagatgggg aaagccatgc gtgcagtatc
     7381 agtagatagc gacgcggcgc aattgatggg gatcaatgta aaccgtacga ttagctttac
     7441 cttcgctttg ggttctgctc ttgcgggtgc ggctggtgtt ctgattgctc tttattataa
     7501 ctctcttgag cctttgatgg gggttactcc aggtcttaaa tctttcgttg ccgcagtact
     7561 tggtggtatc ggaattattc ctggtgcggc tcttggtggc tttgtgattg gtctattgga
     7621 aacctttgcg acagcctttg ggatgtcaga tttccgtgat gccattgttt atggaatctt
     7681 gttgttgatc ttgattgtcc gcccagctgg tatccttggt aagaatgtga aagagaaggt
     7741 gtaagcgatg aaggaaaatt taaaagttaa tattctatgg ttactccttt tgttagctgg
     7801 ctatagcttg attagtgtac tggtttcagt cggagtactt aatctattct atgtacagat
     7861 tttacaacaa attggaatta atattatttt ggctgttggt ctcaacttaa tcgttggttt
     7921 ttcaggacaa ttttcacttg gtcatgctgg tttcatggcg attggtgcct atgcagcagc
     7981 tattattggt tctaaatcac caacctacgg tgccttcttt ggagctatgc ttgtaggagc
     8041 tttgctttca ggagcagttg ccttacttgt cggcattcca accttgcgct tgaaggggga
     8101 ctatcttgcg gtagcaactc taggtgtttc tgaaattatc cgtatcttta tcatcaatgg
     8161 tggaagcctt acaaatggtg cggcaggtat tttagggatt cctaacttta caacttggca
     8221 aatggtttac ttctttgtcg tgattacaac cattgcaacc ttgaacttct tgcgtagccc
     8281 aattggtcgt tcaaccctct ctgttcgtga agatgaaatc gctgctgagt cagttggggt
     8341 taatacgact aaaattaaaa tcatcgcttt tgtctttggt gccattactg caagtattgc
     8401 tgggtcactt caggcaggat ttatcgggtc tgttgtaccg aaagattaca ccttcatcaa
     8461 ctcaatcaac gttttgatta ttgttgtatt tggtggactc ggttccatta caggtgcgat
     8521 tgtttcggct attgttctgg gaattttgaa tatgcttctc caagatgttg ctagtgtgcg
     8581 tatgattatt tacgctttgg ccttggtatt ggtaatgatt ttcagaccag gtggactcct
     8641 tggaacatgg gaactgagcc tatcacgttt ctttaaaaaa tctaagaagg aggaacaaaa
     8701 ctaatggcat tacttgaagt aaaacagtta accaaacatt ttggtggtct aacagctgtt
     8761 ggagatgtga ctcttgaatt gaacgaaggg gaactggttg gattaatcgg tccaaacgga
     8821 gctgggaaaa ccaccctttt caaccttttg accggtgttt atgaaccaag cgagggaaca
     8881 gtaaccctag atggtcacct tttgaatggg aaatcacctt ataagattgc ctctttggga
     8941 cttggacgta ctttccaaaa tatccgtctc tttaaagatt taacagtttt agataatgtt
     9001 ttgattgctt ttggaaacca tcacaaacag catgttttta ctagtttctt acgcttacca
     9061 gctttttaca agagtgaaaa agaattaaag gataaagctt tggaattgtt gaaaatcttt
     9121 gatttagatg gtgatgcaga gactcttgct aaaaatcttt cctacggaca acaacgtcgt
     9181 ttggaaattg ttcgtgccct tgctacggaa cctaaaattc tcttcttaga tgaaccagca
     9241 gcaggtatga acccacagga aacagccgaa ttgactgagt taattcgtcg tatcaaagat
     9301 gagtttaaga ttacaatcat gttgattgaa cacgatatga atctggtcat ggaagtaaca
     9361 gaacgtatct acgtacttga atatggccgt ttaatcgctc aaggaactcc agacgaaatt
     9421 aagaccaata aacgcgttat cgaagcttat ctaggaggtg aagcctaatg tctatgttaa
     9481 aagttgaaaa tctttctgtg cattacggta tgatccaagc agttcgtgat gtaagctttg
     9541 aagttaatga aggagaagtt gtttccctta tcggtgccaa cggtgcaggt aagacaacta
     9601 ttcttcgcac cttgtcaggt ttggttcgac caagttcagg aaagattgaa tttttaggtc
     9661 aagaaatcca aaaaatgcca gctcagaaaa tcgtggcagg tggtctttca caagttccag
     9721 aaggacgcca cgtctttcct ggcttgactg ttatggaaaa tcttgaaatg ggagctttct
     9781 taaagaaaaa tcgtgaagaa aatcaagcaa acttgaagaa ggttttctca cgctttcctc
     9841 gtcttgaaga acgtaagaac caagatgcag ctactctttc aggaggggaa caacaaatgc
     9901 ttgccatggg acgcgctctt atgtcaacac caaaacttct tcttttagat gaaccatcaa
     9961 tgggacttgc cccaatcttt atccaagaga tttttgatat cattcaagat attcagaagc
    10021 aaggaacaac cgtcctcttg attgaacaaa atgccaataa agcactcgca atctctgacc
    10081 gaggatatgt actggaaaca gggaaaatcg tcctatcagg aacaggaaaa gaactcgcct
    10141 catcagaaga agtcagaaaa gcatatctag gtggctaaaa caatccagtg gattgtttta
    10201 gtcggcagat gaagattacg aagtaatcat caatatagtc cgggggacct ttttagtcgg
    10261 tagattgaga ttgcaaacaa atctgcatct acattgaaag ctgaatttct aataattgaa
    10321 aaaatcgaat gaaaagtttc ttaccttcat tcacagaact cgatttcaga gctcttttgc
    10381 tagcttattc atacttttct gaatttcgaa aaagaaatgt aagcgtttga tagatttgca
    10441 aaaagattgt ataataggga taagaataga aaaggagaag tctcatggca gttaaagatt
    10501 ttatgacccg caaggtagtt tatattagtc cagatacaac agtatctcat gcagcagatt
    10561 tgatgagaga gcaaggtttg caccgtctgc ctgttatcga aaatgatcaa ttagttggtt
    10621 tggtgactga gggaaccatt gcacaagcaa gtccatctaa agcaacaagt ctttctatct
    10681 atgagatgaa ttatcttctg aataagacaa aagtaaaaga tgtcatgatt cgcgatgttg
    10741 tcactgtctc aggctatgct agtctagaag atgcaactta tctgatgttg aaaaataaga
    10801 ttagtattct ccctgtcgta gataaccatc aagtatacgg agttattact gaccgtgacg
    10861 ttttccaagc ctttcttgaa attgcaggtt atggcgaaga agggattcgt gtacgctttg
    10921 ttacagaaga tgaagttggt gttcttggaa aaattgtttc tttgattgta gaagaaaatt
    10981 tgaatatctc ccatacagtc aatattccgc gtaaggatgg taaggtgatt atcgaagtgc
    11041 aaatcgatgg atcaattgat ttaccagcct tgaaagaaaa atttgaagca aatggtattc
    11101 aagtggaaga aatcgctcgc acttcagcaa aagtcttgta agaagggaag cccaaaggct
    11161 tcttttttca tgaaaagggg attagagaaa aagatggaaa gaaatgataa aatatgctat
    11221 aatgaaataa tgtaaaaaag gagtatttat ggacatttca gtaattcgtc agaaaattga
    11281 cgcaaatcgt gaaaaattag cttctttcag ggggtctctt tgacctcgaa gggctagagg
    11341 aagagattgc catcttggaa aacaagatga cagaacctga tttttggaac gataatattg
    11401 cggcccaaaa aacgtcgcaa gaattaaatg aattaaaaaa cacttacaat accttccata
    11461 agatggaaga gttgcaggat gaagtcgaaa ttttattgga ttttttggct gaagacgagt
    11521 cagtgcatga tgaactggta gcgcagttag ccgaacttga taagataatg accagctacg
    11581 agatgactct actcttgtca gaaccttatg accacaacaa tgccatcttg gaaatccatc
    11641 caggttctgg tggtactgag gcgcaggact ggggtgatat gttgcttcgt atgtatactc
    11701 gttatggtaa tgctaaaggc tttaaagtgg aagtgttgga ttaccaagca ggtgatgagg
    11761 ctggtattaa gtcggtaact ttatcatttg aagggcctaa tgcctatggt ctcctcaagt
    11821 cagaaatggg tgttcatcgc ttagtgcgaa tctcaccatt tgactctgcc aaacgtcgcc
    11881 atacctcttt cacatctgta gaagtgatgc cagaattgga tgatactatt gaagtggaaa
    11941 tccgtgaaga tgatatcaag atggatacct tccgttcagg tggtgccggt ggacaaaacg
    12001 tcaataaagt ttcaacaggt gtacgtttaa cccacattcc aactggaatt gttgtccaat
    12061 caacagtgga tcgtacccag tatggaaata gagatcgtgc catgaagatg ttgcaggcta
    12121 agctctatca aatggagcaa gataagaagg ctgcggaggt agattctctc aaaggtgaga
    12181 aaaaggagat cacttgggga agccaaatcc gttcttatgt cttcacgcct tatactatgg
    12241 taaaagatca ccgaactagc tttgaggttg ctcaggtaga taaggttatg gatggggacc
    12301 tagatggttt tatcgatgct tatctcaagt ggcgaattag ctaagataga aaggaactca
    12361 catgtcaatt attgaaatga gagatgtcgt taaaaaatac gacaacggaa cgactgctct
    12421 acgcggtgtt tcggtcagcg ttcaaccggg ggaatttgct tacatcgtag gaccttcagg
    12481 agcagggaag tcaactttta ttcgttctct gtatcgtgaa gtaaaaatcg ataaaggaag
    12541 tctatcagtt gctggtttta atctggttaa gatcaaaaag aaagatgtcc cgcttctacg
    12601 tcgtagtgtt ggggttgtct tccaagatta taaattgtta ccaaagaaaa ctgtctatga
    12661 aaatattgct tacgctatgg aagtaatcgg ggaaaatcgc cgtaatatca aaagacgagt
    12721 gatggaagtt ttggacttgg ttggattgaa gcataaggtt cgttctttcc caaatgaact
    12781 ctcaggtggg gagcaacagc gaattgcgat tgcgcgtgca attgtaaata atcccaaagt
    12841 attgatagct gatgagccaa caggaaatct ggatccggat aattcatggg aaattatgaa
    12901 tctcttggaa cggattaacc tacaagggac aactattttg atggcgactc ataatagcca
    12961 gattgtaaat accttgcgcc accgtgtcat tgccattgaa aatggccgtg tcgttcgtga
    13021 cgaatcaaaa ggagagtatg gatacgatga ttagtagatt ttttcgccat ttatttgaag
    13081 ccttaaaaag tttgaaacga aatggttgga tgacagtagc tgctgtcagt tcagtcatga
    13141 ttactttgac cttggtggca atatttgcat ctgttatttt caatacagcg aaactagcta
    13201 cagatattga aaataatgtc cgtgtagtag tttatatccg aaaggatgtg gaagataata
    13261 gtcagacaat tgaaaaagaa ggtcaaactg ttacaaataa tgactaccac aaggtatatg
    13321 attctttgaa gaacatgtct acggttaaaa gtgttacctt ttcaagtaaa gaagaacaat
    13381 atgaaaaatt aaccgagata atgggagata actggaaaat ctttgaagga gatgccaatc
    13441 ctctctatga tgcctatatt gtagaggcaa acactccaaa tgatgtaaaa actatagccg
    13501 aagatgctaa aaaaattgaa ggtgtctctg aggttcaaga tggcggtgcc aatacagaaa
    13561 gactcttcaa gttagcttca tttatccgtg tttggggact agggattgct gctttgttaa
    13621 tttttatcgc agttttcttg atttcaaata ccattcgtat taccattatt tcccgcagtc
    13681 gcgaaattca aatcatgcgc ttggtcggag ctaaaaacag ttatatccgt ggaccgttct
    13741 tgttagaagg agcctttatc ggtttattgg gagctatcgc accatctgtt ttggtcttta
    13801 ttgtttatca aattgtttac caatctgtca acaaatcgtt ggtagggcaa aatctatcca
    13861 tgattagtcc agatttattt agtccgttga tgattgccct actatttgtg attggggttt
    13921 tcattggttc attgggatca ggaatatcca tgcgccgatt cttgaggatt taggtaaaat
    13981 agctgctttt atgaggagat tgtaaaatct ccttttttgc tacaagagtt tttgaaaaga
    14041 gatgcgtaga agaaaagagc ttccaaagaa gtcccccaga gaagacttct tgatggctaa
    14101 tttgaacttg aaatttggcg cactagaaat tttttagaaa aaagtgtaat ttttttataa
    14161 aagcctttac aaaaaaaatt aaagtggtat aattaaatca tagaaggtgc aaacgttttc
    14221 gtaaaacgtt tgcctaaata aaaataaagg agatttgaat gatgaaagat acattcaaaa
    14281 atgtcttgtc tttcgaattt tggcaaaaat tcggtaaggc tttgatggta gttatcgcgg
    14341 ttatgccggc tgctggtttg atgatttcaa tcggtaagtc tatcgtgatg attaacccaa
    14401 cctttacacc acttgtcatc acaggtggaa ttcttgagca aatcggttgg ggggttatcg
    14461 gtaaccttca cattttgttt gccctagcca ttggaggaag ctgggctaaa gaacgtgctg
    14521 gtggtgcttt cgccgctggt cttgccttca tcttgattaa ccgtatcact ggtacaattt
    14581 ttggtgtatc aggcgatatg ttgaaaaatc cagatgctat ggtaactact ttctttggtg
    14641 gttcaatcaa agttgctgat tactttatca gtgttcttga agctccagcc ttgaacatgg
    14701 gggtattcgt agggattatc tcaggttttg taggggcaac tgcttacaac aaatactaca
    14761 acttccgtaa acttcctgat gcactttcat tcttcaacgg gaaacgtttc gtaccatttg
    14821 tagttattct tcgttcagca atcgctgcaa ttctacttgc tgctttctgg ccagtagttc
    14881 aaacaggtat caataacttc ggtatctgga ttgccaactc acaagaaact gctccaattc
    14941 ttgcaccatt cttgtatggt actttggaac gtttgctctt gccatttggt cttcaccaca
    15001 tgttgactat cccaatgaac tacacagctc ttggtggtac ttatgacatt ttaactggtg
    15061 cagctaaagg tactcaagta ttcggtcaag acccactatg gcttgcatgg gtaacagacc
    15121 ttgtaaacct taaaggtact gatgctagtc aataccaaca cttgttagat acagtacatc
    15181 cagctcgttt caaagttgga caaatgatcg gttcattcgg tatcttgatg ggtgtgattg
    15241 ttgctatcta ccgtaatgtt gatgctgaca agaaacataa atacaaaggt atgatgattg
    15301 caacagctct tgcaacattc ttgacagggg ttactgaacc aatcgaatac atgttcatgt
    15361 tcatcgcaac acctatgtat cttgtttact cacttgttca aggtgctgcc ttcgctatgg
    15421 ctgacgtcgt aaacctacgt atgcactcat tcggttcaat cgagttcttg actcgtacac
    15481 ctattgcaat cagtgctggt attggtatgg atatcgttaa cttcgtttgg gtaactgttc
    15541 tctttgctgt aatcatgtac tttatcgcaa acttcatgat tcaaaaattc aactacgcaa
    15601 ctccagggcg caacggaaac tacgaaactg ctgaaggttc agaagaaacc agcagcgaag
    15661 tgaaagttgc agcaggctct caagctgtaa acattatcaa ccttcttggt ggacgtgtaa
    15721 acatcgttga tgttgatgca tgtatgactc gtcttcgtgt aactgttaaa gatgcagata
    15781 aagtaggaaa tgcagagcaa tggaaagcag aaggagctat gggtcttgtg atgaaaggac
    15841 aaggggttca agctatctac ggtccaaaag ctgacatttt gaaatctgat atccaagata
    15901 tccttgattc aggtgaaatc attcctgaaa ctcttccaag ccaaatgact gaagcacaac
    15961 aaaacactgt tcacttcaaa gatcttactg aggaagttta ctcagtagca gacggtcaag
    16021 ttgttgcttt ggaacaagta aaggatccag tatttgctca aaaaatgatg ggtgatggat
    16081 ttgcagtaga acctgcaaat ggaaacattg tatctccagt ttcaggtact gtatcaagca
    16141 tcttcccaac aaaacatgct tttggtattg tgacggaagc aggtcttgaa gtattggttc
    16201 acattggttt ggacacagta agtcttgaag gtaaaccatt tacagttcat gttgctgaag
    16261 gacaaaaagt tgcagcagga gatctccttg tcacagctga cttgaatgct atccgtgcag
    16321 caggacgtga aacttcaaca gtagttgtct tcacaaatgg tgatgcaatt aaatcagtta
    16381 aattagaaaa aacaggttct cttgcagcta aaacagcagt tgctaaagta gaattgtaat
    16441 atacttgagg ttggaagctg tattccaacc tcttattttg ggagaaaaga atgaaatttt
    16501 taacactcaa tactcacagt tggatggaga aagaagcaga ggaaaaattc cagattttgc
    16561 ttgaagatat tcttgaaaag gactatgatt tgatttgttt tcaagaaatc aatcaggaga
    16621 tgacctcgtc agaggtggag gttaatgacc tttatcaagc tttgccagca gctgagccta
    16681 ttcaccaaga ccattatgtt agactcttgg ttgaaaagtt gttagagcaa gggaaaaatt
    16741 actactggac ctgggcttat aaccatatcg gctatgaccg ctaccacgaa ggtgtggcta
    16801 tcttgtctaa aacacctatt gaagccagag aaattttggt ttcagatgtg gatgatccaa
    16861 cagactatca tactcgccgt gttgccctag ctgaaactgt agtcgatggc aaggagctag
    16921 cagttgccag tgttcatctc tcttggtggg ataaaggttt ccaagaagaa tgggcacgat
    16981 ttgaggctgt cttgaaaaaa ttgaacaagc cacttttact agctggagat tttaacaacc
    17041 cagcaggtca ggaaggttac caagctattt tagctagtcc attaggctta caagacgcat
    17101 ttgaagttgc tcaagagaaa agtggtagct atactgttcc gcctgaaatt gatggctgga
    17161 aagggaacac tgaacccctt cgaatcgatt atgtctttac taccaaagag ttagcggtgg
    17221 aaaatttaca tgtcgtattt gatggtaaca agagtccaca agtgagtgat cactatggct
    17281 tgaatgcggt attaaattgg aaataaaatc aaaaaatgaa agggagcgag tcctttcatt
    17341 tttttacaaa aatccctata attactattt tggagaagga gttttttgta tatttgtata
    17401 ttatgaggaa atatccacaa ataagttttt aaaactttac ggtcaaaaaa aaatcgctaa
    17461 tattaactat ttatgataga atgaaaatta tgaaataaaa ggaggactgg aatgtttttt
    17521 caggatagaa agataaaata ttcaatccgc aaattgtcag ttgctactgt gtcccttgcg
    17581 attggatttt tgtttgcgcc tgcggcgctt ggagtcgctc aagtagctca agctgatgag
    17641 ctttcaacta ctgaacaagt ggagaataaa gcagagaatc aggtctcggt ggtctctttt
    17701 gcaacagagc aagaagaaag tgaaacgact tatgttgata cgacgaataa agtgacttgg
    17761 acatttgcag gatacgataa agaaaaaatt gttgtaggaa aaggcagaca gactttcctt
    17821 ggaagctggg tacctactcc aaatccagaa tatgtattca aatcatctaa agcaggtgtt
    17881 ccattaccac aaagtatttt gggaatgctt ccaaaggatg aagcttctta taaggttggt
    17941 gacaccattg tagccaaaca acctgctgta gaatcagtag tcgaagaaga aaaagactat
    18001 gtctggacct tcaaaggtta tgatcagaag aatgcgacgt acaatggcaa gcgtgtgaca
    18061 tttacaggta tctgggaagt aacgcctaga ccgcatcatg taagctatac ttttgtaagt
    18121 gttacatctg gtgttgattt gcctaaattt atccagaaga aagcaccaaa agatggctca
    18181 acttacttca ataggacgag agtttttgca gaagagccga caacaa
//
LOCUS       DAVAGB010000041        18161 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVAGB010000041 DAVAGB010000000
VERSION     DAVAGB010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18161
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.041"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(196..2046)
                     /locus_tag="VQO19_001597"
     CDS             complement(196..2046)
                     /locus_tag="VQO19_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET1349831.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(2088..3245)
                     /locus_tag="VQO19_001598"
     CDS             complement(2088..3245)
                     /locus_tag="VQO19_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET1349832.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML"
     gene            3303..4469
                     /locus_tag="VQO19_001599"
     CDS             3303..4469
                     /locus_tag="VQO19_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HET1349833.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            4608..4934
                     /locus_tag="VQO19_001600"
     CDS             4608..4934
                     /locus_tag="VQO19_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET1349834.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            4921..5514
                     /locus_tag="VQO19_001601"
     CDS             4921..5514
                     /locus_tag="VQO19_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HET1349835.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTILAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            5507..6418
                     /locus_tag="VQO19_001602"
     CDS             5507..6418
                     /locus_tag="VQO19_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HET1349836.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTDNHFHAEN
                     IQVHGKVELTAKDYLRIILDQKENQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            6480..7544
                     /locus_tag="VQO19_001603"
     CDS             6480..7544
                     /locus_tag="VQO19_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349837.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEDSEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(7615..8461)
                     /locus_tag="VQO19_001604"
                     /pseudo
     CDS             complement(7615..8461)
                     /locus_tag="VQO19_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
     gene            complement(8736..9722)
                     /locus_tag="VQO19_001605"
     CDS             complement(8736..9722)
                     /locus_tag="VQO19_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HET1349838.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(9994..11469)
                     /locus_tag="VQO19_001606"
     CDS             complement(9994..11469)
                     /locus_tag="VQO19_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HET1349839.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(11727..12650)
                     /locus_tag="VQO19_001607"
     CDS             complement(11727..12650)
                     /locus_tag="VQO19_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET1349840.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(12664..13593)
                     /locus_tag="VQO19_001608"
     CDS             complement(12664..13593)
                     /locus_tag="VQO19_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET1349841.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(13912..14133)
                     /locus_tag="VQO19_001609"
     CDS             complement(13912..14133)
                     /locus_tag="VQO19_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349842.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQEELQKAVLF
                     LADEKGSEHTEAELIDNLKEVIAKLKANA"
     gene            complement(14087..14347)
                     /locus_tag="VQO19_001610"
     CDS             complement(14087..14347)
                     /locus_tag="VQO19_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349843.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKALADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            complement(14678..14833)
                     /locus_tag="VQO19_001611"
                     /pseudo
     CDS             complement(14678..14833)
                     /locus_tag="VQO19_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(15010..15621)
                     /gene="rpsD"
                     /locus_tag="VQO19_001612"
     CDS             complement(15010..15621)
                     /gene="rpsD"
                     /locus_tag="VQO19_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HET1349844.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(15816..16868)
                     /locus_tag="VQO19_001613"
     CDS             complement(15816..16868)
                     /locus_tag="VQO19_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET1349845.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(16865..17563)
                     /locus_tag="VQO19_001614"
     CDS             complement(16865..17563)
                     /locus_tag="VQO19_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET1349846.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(17730..>18161)
                     /locus_tag="VQO19_001615"
     CDS             complement(17730..>18161)
                     /locus_tag="VQO19_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HET1349847.1"
                     /translation="GTQTYSATVNVYGNKDGKPDLDNIVATKKVTIKINVKETSDTAN
                     GSLSPSNSGSGVTPMNHNHATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSE
                     DKAMLPNTGETQTSMASIGFLGLALAGLLGGLGLKNKKEEN"
BASE COUNT         5364 a         3915 c         3386 g         5496 t
ORIGIN      
        1 aggttgtgga tagaactgac gaagtcagct ctaaacactg ttttgaggtt gtggatagaa
       61 ctgacgaagt cagtaaccat atacggcaag gcgacgttga cgtggtttga agagattttc
      121 gaagagtata agtctctaca taataaaacg catagtacca aggttaacaa acttgatact
      181 atgcgttttt cttttttatt caatgtgggt tgtttgatta gcaaaggcga taatagcttg
      241 cttcaactca tctccactga gagtgcggaa ctctccaatc ttttgattga tggattctaa
      301 aggcatgaca ttaaccttac caacgaaaat cttatccata acttgattgt caacgagttc
      361 ggttgatacc aagagttctt cgtagagttt ttcacctggg cggattccaa cttcaacgat
      421 tggaatttca ctttcagtgt ggccacttag aagcaccatc ttcttggcca agtcataaat
      481 cttgactggt ttgcccatat caaggataaa gacttcccca tctttggcat aagcaccagc
      541 atggataacc agacggctag cttctggaat ggtcataaag taacgggtca tgcggaagtc
      601 tgtcaccgtt acaggcccac cttcagcaat ctgacgttca aagactggaa tgacactacc
      661 acggctacca agaacattcc caaaacgaac tgcacagtag gttgattggc tacgttggtt
      721 aaagccagtg acaatcaact ccgccacgcg cttggttgct cccataacat ttggtggatt
      781 aactgcctta tctgtcgaaa tcataaccat cttaggcacc ttggcttcat caacggctct
      841 agcaacattg taagttccac ggatattgtt tttgaaggct tcttttggat tgcgctccat
      901 cataggaaca tgcttgtggg ctgccgcatg ataaacaata gcaggtttgt actgctcaaa
      961 gacttgcaac aaacgatcat agtcttgaat gtccgcaatc acaggtacat aatcaatccc
     1021 ttggaactta cgaatcaatt catgataaac aaggtagatt gagttttccc catgaccgag
     1081 caagacaatg cgttcaggat tgaagcgact aacttgacga cagatttcag aaccgattga
     1141 acctccagct cctgtgacta agatggtctt acctgtcagt tcggcaccca gacgcgattc
     1201 gtcaagacgg atttcctgac gacccaaaag gtccgtaata tcaatttttt ggaagccagt
     1261 acctgcttgg tgaaggccct gaacaacagt ttcaacctta ggcatcttgt aacatttgac
     1321 acccagctta ttacacatct gcaagatacg ctcatattct gacggatcca gcgacggaat
     1381 cgcaacgatg acacgctcga tttgatggcg tttggctaat tcaggcagat tgtcataaga
     1441 gcccaaaaca ggaataccac caagtttttg accctttttc ttagaatcct tatccaaaat
     1501 accgaccagt tctaattcac tggttggatg ttggtaacta tccataaaga gagccccacc
     1561 atcaccggca ccaatcaaga aggtccgacg gtgttctcca tcaccactac cttttttgcg
     1621 tctggagtag attaactgcc aagtaatccg tggcaataaa atcaagaagg tactcaacaa
     1681 gataaagaga atgatgaaac ggatggagaa gagtggcaag aaggcataac agatactata
     1741 tgacaagaca ctgctagcag tcacaccaaa aaagattttc atgaaatccg taatcttgct
     1801 gtaacgacta atgctcgcgt tcaaccccca aaaaccaatc atcaattgat agaacaagaa
     1861 ggccaaactc gtatagataa tgtagtcaac aggtgctgga ttaatcagcc cataaaataa
     1921 aatataagat acaatgatgg aaaccaccat actgaaaata tcaaatattc cccagaaaac
     1981 ctgcttttgt tgtttattta aaatttccac cagatcaatc acataatctg ttagtttttt
     2041 attcatagaa atctactcct ccttaaaaga gttttactat attgttatta tagcatattt
     2101 ttatttattt ggcttatttt atccaaataa attattgttc tcttgtactc cttcttccat
     2161 ttaaatcctc taattaaacc tacaatcgtc ccaaggccat aagcaaagtg aatggaaaat
     2221 aaaagaaagg gcatcacaat tagaaatcca tttttatgtt ttaataaagt cagcaaagtg
     2281 agtaatgaca aaagtagaaa ataggcacct aatagtaaag ttatgaatac gaatgtgatc
     2341 ggtaacaatg ctagactaaa cacaagactc aaaacaaata aacaaggaac atagtgaaat
     2401 aatgataaac acttaaactg aacatgactt gtcaagccaa tccacaaacc atttgaatac
     2461 ttttgatgca gcattttctt gaatgttggt cgaatatact gataagatag aatacttggg
     2521 ctatagcgga ttttataacc atgttctcga attctataat gaatatcatt atcttcagtt
     2581 cggccaagtt gctcatttac taaaccaacc ttctggaaaa cctctcgttt atacatccca
     2641 tgaaaaatag aagaaacata tctatcctcg gaactatttc gataattggc aatgctactg
     2701 ccaaacatat tttcctcaac aagatgcaag gtctctgccc attttccttt tccttcgaca
     2761 atcgtcggtc taggcccccc acagacaaat tcaccttgtt gaataatagc cacattgttc
     2821 attacaaaac tctcagtaac ttttgaatga gcatcaattt ttaaaataag gtcccctaca
     2881 gaatgtttaa ctcccaggtt aaaaccacta gcttgatttt tcttaggatt gttatacaat
     2941 ctaattgagt taaactctgt atcttccttt ataaattgct gaatgatagc tgtggtccca
     3001 tctgtggaca tagcatttat aaatagaatt tcaatattct ctttaggata ggtttgattt
     3061 tttaagtctt caattagacc aggcagatat ttttcttcat tgtatgcact gattacaatg
     3121 gatacgagaa gactttcaac attttgagtc actactactc tcctgaattt ttccttccac
     3181 cattctatca taattttcaa gactttccca tttttatctt gaaagccaga aaccttactt
     3241 gacattatag tgaaaaagcc ttaaaataag ctgttattaa aatcagctag aagaggtatt
     3301 atatgaaaaa gcaatcactc ttttttgttc caggtattat cctgattggt gtttccttgc
     3361 gaactccttt tactgtttta cccattattt tgggaaatat ttcgcaaggt ctggaggtag
     3421 aagttagttc gcttggtgtc ttgaccagcc tgcctctcct tatgtttacc ctcttttcac
     3481 cattttctac ccgactggct cagaaaatcg gcttggagca tctcttcacc tacagcctct
     3541 tcttcttgac catcggctca cttattcgac taatcaatct gcccctgctc tatctaggaa
     3601 ccttgatggt tggggcaagt gtcgcagtca tcaatgtcct gcttcctagt cttatccaag
     3661 ccaatcaacc aaagaaaatt ggttttctga ccaccttata tgtaacgtct atggggattg
     3721 caacggctct ggcttcctat ctagctgtgc ccattacaca agccagttct tggaaaggac
     3781 ttatccttct cctcacgtta ctctgtctag caactttttt ggtctggctc ccaaatcacc
     3841 gctataatca tagactagct ccacaaacca aacaaaaaag tcaaataaag gtcatgcgta
     3901 ataaacaggt ttgggcaatt attatctttt caggttttca atccttgatc ttttacaccg
     3961 tcatgacctg gttacctacc atgtctatcc atgcaggtct atccagtcac gaagctggct
     4021 tgctgacttc tatcttatct ctgattagca ttcctttttc aatgaccatc ccaagcctga
     4081 caaccagttt atctactcgc aaccgtcagc tcatgctcac tctggtttca ctagctggtg
     4141 tggtcggcat ttccatgctc tttttcccaa tcaataattt catttactgg cttgccatcc
     4201 atctcctcat cggaaccgca accagcgccc tcttccctta tctcatggtc aacttttcac
     4261 tcaagacaag cgcccctgaa aagacagccc aattgtccgg cctatctcaa acaggaggct
     4321 atatcctagc agcctttggg ccaaccctct ttggttacag ttttgacctg ttccactctt
     4381 gggtaccatc tgtagctgcc ctcttgctca tcgatatcct gatgactgtg gccctcttta
     4441 cagtggacag agcggataag atcctttaaa cttctagttt tagctagaag ttttttatat
     4501 ataaaaattt tacacatttc tcttgacagg gctttctttt agatgtacaa tgtatgtgta
     4561 gaaaaattat atataaaaat cttacacatt agaaaaggag gtttcccatg tactttccaa
     4621 catcctctgc cttgattgaa tttctcatct tggccgtact ggagcagggt gattcttatg
     4681 gttatgagat tagccaaacc attaagctga tcgctaatat caaagaatcc acactctatc
     4741 ccattctcaa aaaattggaa ggcaatagct ttctgacaac ctattctaga gagttccaag
     4801 gtcgcatgcg caaatactac tccttgacaa acggtggtat agagcagctc ttgaccctaa
     4861 aagatgaatg ggcactctat acagacacca tcaatggcat catagaaggg agtatccgcc
     4921 atgacaagaa ctgaatacct gactcagcta gaactctatc tcaagaaact acctgaagct
     4981 gaccgtatcg aagccatgga ctatttcaga gagctctttg acgatgctgg agtcgaagga
     5041 gaagaagaac tcatcgctag tttgggaact cccaaagaag cggcccacga agttctatcc
     5101 aatcttctcg ataaaaaaat caatgaagca cccgctcaaa aaaataaccg acaaatttta
     5161 catatcgcct tgttagccct ccttgcagca cctatcggca ttcctctggg aatcgccatc
     5221 ctcgtgaccc tgttcgcaat ccttgtagcc gctttgactg tcattctggc tttctttgca
     5281 gtttccatac tgggtatcat cggcggattc ctatttttag ttgaaagttt cactatcctc
     5341 gcccaagcca aatcagcctt tatcttgatt tttggttctg gtttactggc tatcggtgct
     5401 tcttcgctag ttttacttgg catttcctat gtagctcgct tcttcggtct actcattgtt
     5461 cgtctggtac aatttgttct taaaaaagga aagagaggta atcagcatgc gtaaatggac
     5521 aaaaggattt ctcatctttg gtgtggtgac taccgttatc ggctttatcc tgctttttgt
     5581 aggtatccaa tctgacggga ttaagagcct actttccatg tccaaagaac ctgtctatga
     5641 tagccgtacg gaaaagctaa cctttggcaa ggaagtcgaa aacctagaaa ttactctcca
     5701 ccaacacacg ctcaccatca cagactcttt cgatgatcaa atccacattt cttaccatcc
     5761 atctctttct gctcaccatg atcttatcac caatcagaac gatagaactc tgagtctcac
     5821 tgataagaaa ctgtctgaaa ctccgtttct ctcttctgga attggtggga ttcttcatat
     5881 cgcaagtagc tactctagtc gttttgaaga agttattctc cgactaccaa aagggagaac
     5941 tctaaaaggg atcaacatct cagccaatcg cggacaaacc accatcataa atgctagcct
     6001 tgaaaatgcg accctcaata caaacagcta tatcctccga attgaaggaa gtcgtatcaa
     6061 aaacagtaaa ctcacaacgc ccaatatcgt taatatcttt gatacagttc ttacagatag
     6121 tcagctagag tcaacagata atcacttcca cgctgaaaat atccaagtcc atggtaaggt
     6181 tgaactgact gccaaagatt atctcagaat catcctagac cagaaagaaa accaacgaat
     6241 taactgggac atctcaagca actatggttc tatcttccaa ttcacaagag aaaagcctga
     6301 atcaagaggt acggaattaa gcaaccctta caaaactgaa aaaaccgatg tcaaggatca
     6361 actcattgcg agatctgatg ataatattga tctaatatcc acaccaagca gacgttgaca
     6421 aaaacgctta catctgctac tatggaagca tatttatcta accaaaagga ggttctacca
     6481 tgaaacaaga atggtttgaa agtaatgatt ttgtaaaaac aacaagcaag aacaagcctg
     6541 aagagcaagc tcaagaggtt gcagacaagg ctgaagaaac gatagccgat ctcgatacac
     6601 caattggaaa aaatactcaa gtagaggagg aagtctctca agctgaagtc gaactggaaa
     6661 gccagcaaga agagaaaatt gaaactcctg aagacagtga agcgagaaca gaaatagaag
     6721 aaaagaaggc atctaattct actgaagaag agccagacct ttctaaagaa acagaaaaag
     6781 tcactatagc tgaagagagc caagaagctc ttcctcagca aaaagcaacc acgaaagagc
     6841 cacttcttat cagtaaatct ttagaaagtc cttatatccc cgaccaagct ccaaaatcta
     6901 gggataaatg gaaagagcaa gtgcttgatt tttggtcttg gctagtggaa gcgatcaaat
     6961 ctcctacaag taagttggaa acaagtatca cacacagtta cacagccttt ctcttgctca
     7021 ttctgttttc tgcatcttcc tttttcttta gtatctatca catcaaacat gcttactatg
     7081 gacatatagc aagcattaac agtcgcttcc ctgagcagct agctccttta actctttttt
     7141 ctatcatctc tatcctagta gcgacaacac tcttcttctt ttcattcctc ttgggtagtt
     7201 tcgttgtgag acgatttatc caccaggaaa aggactggac gctagacaag gttctccaac
     7261 aatatagtca actcttggca attccaatct tcctcactgc tattgctagt ttctttgctt
     7321 tctttgatag cctacgattt acagccctct tgtgtgtgat tagcattgga atcattctgc
     7381 ttgccagtct ccatatcatt acaagaccaa gtcaagcaag tgaaaccgac tccttctatc
     7441 aattattctt gtctgtcctt gtgaacggag ttattatcct cctcttcttt gtagctgaag
     7501 tggcactgat tggagattat cttcgtatct tggcctttct ttaaaattca atcctgtcat
     7561 ccttggcagg atttttctat ttcaaaaaag caagtcgatt gacctgcttc tgctttactt
     7621 ttcttgtgct aatgttttaa aatcttgtcc taggatgggt tgtacttcta attgattggc
     7681 gtctagttgg tggtaaaatg ctgatggtag tgactctagg aattttgcat agtccaagcg
     7741 ggcgatggct tcatagtctt ctggtttaga gccatctcct gtgatttgaa ccaagtcgat
     7801 ctcccactgc acttccttat ccaccaattg ctccatatag gcagcaggaa caaatggttc
     7861 tctcggtaaa acggtcttga cgccttgagc caaatgataa acaccgtgca cttgcccttc
     7921 tccatcctga tagaaggaaa ctcttgcaaa gtaggcatct gtctcttgaa ccgcacgcac
     7981 acgcgcttca aactgggcca agccatctgc ctctaaaaag cttttcaagt tctcacgact
     8041 aaagaaaata ggattaaaaa ttccttggca aatcgtaaaa cgagctacag ggtctgctag
     8101 ataggcttga atacttgctt ggaaataagc ttcaaaatca aaaccatcta gcccttcaat
     8161 atcagtccct gtataagcaa gcaaagcatc taaaaatgac ttgataatct gccagtctgt
     8221 ctttgttagt aggtcaggaa gatcgacacg gtaagccttt tgaccatcag cataactgac
     8281 cttaaaaaga aattgtgatt gccccattat cgcacagacg attaagaggc tgacggagat
     8341 agactacatc atagctatgt gactccaaac cgtctagcaa ggccaagatc gacttggcat
     8401 tcaaaatctc ttgttctcct aaaatgctct gtttatttgg aataaaaaat gtttttgcca
     8461 taactggact cctttgaaat cgtttacata cagtatacct tatttttctg aaagatacaa
     8521 aaacaaactt tatattcttc gaaaatctct tcaaaccgcg tcagcttcgc cttgccgtag
     8581 atatatgtaa ctgacttcgt cagtcttatc tacaacctca aagcagtgct ttgagcagcc
     8641 tgcagctagc ttcctagttt gctctttgat tttcattgag tattagattt ttgagtacaa
     8701 agcatagaaa aacagcccct gaggactgtt tgatcttata cagtagctgc ctgatccaag
     8761 ctttcaccga tagcggctag gcgctcaatc acttcagctt gtgtcaattc attttttgaa
     8821 acatagcggt tacgtgggtg aacacggcac tcgtgtgagc atccacgaag gtacttgtct
     8881 tcattttctt ctgatgtcaa gatacgacgg ttacagaagg gatttccaca gttgacataa
     8941 cgttcacatg gtgttccatc aaaccagtct ttccctacga tggttgggtt gacatggttg
     9001 acatcaacgg caatacgctc gtcaaagacg tacattttcc catcccaaag ctcaccttga
     9061 acttctgggt ctttaccgta agttgcgatt cctccgtgca attggccaac atctttgtaa
     9121 ccttcacgaa ccatccagcc tgagaatttc tcacagcgaa caccacctgt acagtaaacc
     9181 acgacacgct tgtccatgaa tttttctttg ttgtcacgga cccattgtgg taactcacgg
     9241 aagttgcgaa tatctgggcg aatagcccca cggaaatgtc ctaggtcgta ctcataatcg
     9301 ttacgtgtgt caaggacaac ggtatcttta tcaagaagcg cttctttgaa ctcttttgga
     9361 gacaagtaag cacctgttgt ttcaagtggg ttgatgtcat tgtcaaagtc gttgtcttcc
     9421 aaaccaaggt ggacaatttc tttcttgtag cgaacaaaca tcttcttgaa ggcttgttca
     9481 ctttcttcgt caatcttgaa ccagagatct tccattcctg gaaggctgtg aacgtagtcc
     9541 atgtattttt gagttgtttc atagtcacct gaaactgttc cgttaattcc ctcgtcagcg
     9601 actaggatac ggcctttaag gccgattgat ttacagaaag ccaagtggtc tgcagcaaat
     9661 tgctctgcat tttcaattgg agtataaagg tagtaaagta agacacgaat atcttttgcc
     9721 ataagatttg ttctcttttc tattcttaaa ttttctaaat tttttattta tctacactag
     9781 tatacctgct tgagaaaacg aatgcaattt atttgactgg aaattgtaga ggattctcga
     9841 aatttcctga atggttaaaa taaggacaag agaaaacagg gatatctata tccttgtgcc
     9901 caaaaaacca ctgccctccc cagaccaatc tgaggaaagc agtgattctt attttaggag
     9961 ttaggaatga atacacgaaa tcaatttagc tgattatttt ttgtttttca agaattcatc
    10021 gtattgtttt tgcatttcgt tcaatacttt ttcgtaggca ccttcagatt tcaatttttc
    10081 catcaattct ggaatcgctt tatctgggtc tacagtacca gtgttgatag ctgtatcaaa
    10141 ttgttgcatt gtgttagcaa tagctgagat ttcagatttc acattgtcag tattaaagat
    10201 aaatccaagc gctggagatt ctttagcttc tgccaattct ttcttagaat tttcgatttg
    10261 ttggtctgta acgttttcgt tgatgtaaag gatccagttg ttaccagtgt tccatccacc
    10321 catgtgagtg tttcctttgt agccatcaag aacgcgaaca cggttttctt taccttcaat
    10381 tttttcccag ttcttgcctt ctggaccgta aacaagaccg ttcaagagtt ctgggttcgt
    10441 attcaagagg ttcaagattt ccattgattt ttctttgttc ttagagttgt ttgagatgac
    10501 aaagttagca acttgtgttg tttggttttt cttgatgaag ttagtaattg gtttgatttg
    10561 gatatctttg ttggcaacac gtgaaagcaa gctgttaccg tagtcagctg gtcctactgt
    10621 ttcttcacga acgaaccaag tatcttgttg aaggtcaaag gaagtatcgc ttgttgcgac
    10681 gtcttttgga atgtagccag cttcatagaa tttgtgaaga gtcttcaagt gttctttgaa
    10741 acgaggtact tcgtaacggt ttacaacttt agtagtatcg ccttcaaggt caataacgaa
    10801 tggaagaccg tttgctactg ggtagtcaaa gttatcagat gggatgaaaa ctttaccaat
    10861 agcaaatggt actacgtctg gagctttttc tttgatttgt ttcaagactg gctcaagagt
    10921 ttcgtaagaa gtaacacctg aaatatcgat accatatttg gcaaggagag ttccgttgaa
    10981 ggcaaagttt tgagatgatg ctacgttggc tgcaactggt acagcgtaaa tcttaccatt
    11041 tacagtatta cccttgatat aagctggatc aagtgccttg taaaggtctt taccttcttt
    11101 tttgtacaat tctgtcaagt cagcataagc acctttttga gcatttacaa tatagttatc
    11161 tgcaaaggcg atatcatagt tttcaccaga tgatgtgata actgacattt tcttaccata
    11221 gtcaccccag ccaaggtatt ggatatccaa tttagcacca actttttctt cgatgatttt
    11281 gttggcattt gctaacaatt catccaagtt atctggtttg tcaccgattt ggtacatttt
    11341 gataacaggt ttgtcacctg aatcagcagc ttttttgctg ttacctgtca aatttccaca
    11401 agcagcaaga cctgcagcca gagcgactac actagcagat gcaaaagcat attttttcca
    11461 gtttttcatg ataaaaactc ctttttttat ttttaaactt ataaacaatg taatgatctt
    11521 atactcaatg aaaatcaaag agcaaactag aaaactagtc gcaggctgct caaagcactg
    11581 ctttgaggtt gtagataaga ctgacgaagt cagttacata tatctacggc aaggcgacgt
    11641 tgacgcggtt tgaatttgat tttcaaagag tattaacttc acacaaggga agttgggaac
    11701 tgagaaatgt tctttttcaa taagcactat tctttcacac caccgatagt caaacctttt
    11761 acaaagtagc gttggaagaa tggatataaa atcgcgattg gaagggtcgc aaccacaacc
    11821 atggccatac gacctgtttc tttcggtaga gcaactccca gttgaccagt caagccgacc
    11881 gctttggcaa tgtagtccat attttgttgg atttgcatga gcaaatattg caatggatac
    11941 aagttgtcac tcttgatgta aagaagggcg ttgaaccagt cattccagaa accaagagct
    12001 gtcaaaagcg tgatggttgc gatacctggt agtgacaatg gcaaacagat ttggaagaaa
    12061 atccgggcct cactggcacc atcgatacga gccgattcga gaatggcttc tggaatggtc
    12121 ttcttgaaga aggaacgcat caagatgata ttgaatggtg agagaagcat tggaacaatc
    12181 aaggcccaaa cagtgtcacc aagctgaagt acacgggtca ccatgatata acctggtacc
    12241 aaaccagcgt tgaacaacat actgagaagg acgaagatgg taaaaaatct gcgatactta
    12301 aaggttgtcc gtgaaatagc gtaggcatag gttgttgtga taaagacatt tgtcaatgtc
    12361 ccaactacgg ttacaaagac agagatgaag agggcttgta ggattttatc cttaaactgt
    12421 gccaaaaact caaaaccgtc taagccaaat tgggatggga agaagctata gccgtattgg
    12481 aggaggcttt tctcgtctgt cactgaaata atgataacga atacaaaagg taggatacaa
    12541 gagagggcaa tcaaacccga aatgatactg aagaagatat ctgctttctt actgaaggag
    12601 tgaatgccga cattatcaat tttttctttt ttaattttct tttttgccat attctcctcc
    12661 tttctagaac aaagctgagt ttggatcgac tcgtcttgca agcaagtttg ataggataac
    12721 cagaatcaaa ccaacaacgg attggtaaag accggctgct gcagccatac cgatatctgc
    12781 tgtctgagtc aaaccattaa aaacatatac gtccaaaacg ttggttacat tgtaaagctg
    12841 accagcattg tgtgggattt gatagaagag accgaagtct gcgcggaaga tatttccgac
    12901 tgcaaggatg gtcaatacag ttacaagcgg agtcaactga ggaatggtta cgttgcgaat
    12961 acgttgccac ttgctagctc cgtccactgt cgctgcttcg tagtaggttg gatcaattcc
    13021 catgatcgtc gcatagtaca tgacactgct atatccaaaa cctttccaaa tacctaggaa
    13081 aagtaggaga tagggccaga tgcccaggtc agcgtagaaa ttgacttctt tgagaccaag
    13141 actttccaat agatgattga acaccccttt atcaatattt aggaaggcat ctgtaaagaa
    13201 actgatgata acccaagaca agaagtaagg gaacaacata gaagtttgga aaatcttcac
    13261 cattctctta gaacggagct cgctgaggat aatggcaatc cctacagata caactaaacc
    13321 tagaaagata aagccaagat tgtagaggac agtatttcgt gtgataataa aggcgtctct
    13381 tgaactaaat aagaatctga aattatcgag tccgacccat ttactattta tgatactatc
    13441 tatgaaacca ttactggtca tgtggtagtc tttgaaggca accacgttcc caaatactgg
    13501 aatgtaaaag aatagaatca accagagtgc ccctggcaaa accatcaaga gaaagatcca
    13561 gttgtctctc aatgtttttg aaaacttttt cataatttcc tcccttttta ttttgatatc
    13621 catctaaaaa ttctttttta gacttttgat aacgattaca ttattagtat actcctattt
    13681 gcaggttagg ttaaactcct aattatagaa aaaactccac aaattatgta gcagatttaa
    13741 aactttatca ccactataaa acaaatgtcc taaatcaatt gtttatttta tctctattag
    13801 cccagtgatg gcgtcactct gttataagca tccaacaacg gggtatactg aaaaatctcc
    13861 agactaggga actcagcgat agttcctaat ctggagattt ttaatatgtt attaggcgtt
    13921 tgctttcaac ttagcaataa cctctttaag attatcaatc aactctgctt cagtatgctc
    13981 agagcctttt tcatctgcca agaacaaaac tgctttttga agttcttctt gagagttttc
    14041 aaggacatcc ttatctactg tttcaaggtt tgagtcttta agaagtttac ttaattcctt
    14101 ggctaatttc ttgagtttga tttgcagact catcttctcc tgctgtttct ttgcccgctg
    14161 tttgtcctcc atccttagtt gctgactggc tttccttaat ggactctagg gaagcaatgg
    14221 catctttgac tgtttgcaag atatcacgta aaccttgctc tgtcaaacta tcatctgcaa
    14281 gagctttctt agcctctgcc aaaaccagac gtgctgaatc tgtggtagga ttcgatacac
    14341 ctgtcaatga tctcaaaaga ttttctaagg tttgagtctg cttactaata ctagactaaa
    14401 atcaaaaagc attacataac agtgatatga aatcaactaa agaagaaatc caaaccatca
    14461 aaacactttt aaaagactct cgtacagcta aatatcataa acgccttcaa atcgttctat
    14521 agtaaaatga aacaagaaca gggcaaatct tataaagaga ttatagaact tttatagtag
    14581 tttgaaataa gatgtgaaca actctatcag gaaagtcaaa ttaatttata gaaatatttt
    14641 agcagccaag gtgtactgtt atagattcaa tacactatac ttggtggttt agctctcctg
    14701 ttttctcttt tagctttaac cagccataaa tggtattacg tgagatttgg aaaacgtgtg
    14761 atgcttctgt tatactacct gttcgctcac aataagagag aactttttta cgaaaatcta
    14821 ttgaatatgc cataaaagat tataccacat tgtgtactat ttttggttca ttttactata
    14881 tcactttgga ctatatcggt ctagttatgt ctaaacgatt atagctggat actaagagaa
    14941 atcaaaaaag cactaaggga gaacgtccca aagtgcttaa tatcaaagcc tatcttattc
    15001 aataaaatat tacaacattt tgttgtagaa ttcaacgaca agtgcttcgt tgatttctgg
    15061 gttgatttcg tcgcgttctg gcaagcgagt caatgaacct tccaattttt cagcgtcgaa
    15121 tgatacgaat gctggacgtc caagagtagc ttctactgct tcaaggattg ctggaacttt
    15181 caatgatttt tcacgaactg agatcacttg acctggagtt acgcggtatg atgggatatc
    15241 aacgcgtttc ccgtcaacaa ggatgtgacc gtggtttacg aattgacgag cttgacgacg
    15301 agtagtcgcg agaccaagac ggtaaacaac gttatccaaa cgacgttcca aaagaagcat
    15361 aaagttgaaa cctaggattc cgcctttgat ttttgtagct tgtacgaaca agttacggaa
    15421 ttgtttttca cctacaccgt aagtgaaacg aagtttttgt ttttcagcca attgcaaacc
    15481 gtattctgac aatttagaac ggttgtttgg tccgtgttgt cctggtacgt agttacgacg
    15541 tgccaattct ttacctgtac ctgtaagtga aaggccaagg cgacgagctt gtttccaaga
    15601 tggtcctgta taacgtgaca tatgaatgtc ctcctgatat aaataatatt tcggtggaaa
    15661 tagtcactta gaaagccctg attcgtgcag atgcccttcg cctaaacagc caaggttact
    15721 tgtcataaga cacctgttga cgagcttcat gctttcctgc tgatatttca cacaaaatct
    15781 attctaccat gaatagctgg atttgtaaag gggttttagg ctttattttc actaccagag
    15841 aggttgagaa cgagggtaaa ggtacttcct agaccgtact ggctgctgac tgtgatttcc
    15901 ccacccaatt gatgggccaa ttcacgcgca atcgcaagtc ctaatccatg accacctgtc
    15961 ttcatgttac gcgaagtttc gacacgataa agacgtttga aaatattttc caaatcctct
    16021 ggggcaatac cctgcccttc atcggtcaca ctgattgaaa gctggtcctt ctccagctta
    16081 gccaccactt ccagcttggt tcctggagca gaatatttaa aagcgttatc gaccagattc
    16141 accaagatac gagaaagctt agcataatct ccctcaatcc gggcagactc tgggattacc
    16201 tgcaagtgga catctcttct ctcctgctca atcaaaaact gaaattcact catgcactca
    16261 attaagagct tgtccagaaa aatactgtct ttactggtag tttccacctg atttctagct
    16321 gtgtttaggg tcaaaaaatt caactcctca accagtttat tgagcctctc cgtctggcgt
    16381 ccaatggttg ctagataatg agcttgctcc gactccttga taatcccatc caaaatccct
    16441 tctaccgtcg cttgaatcga agtgataggg gtcttaatat catgcgacaa ctgggcaatc
    16501 atcaagccct tttctcgttc gctttcttcc aaggaatcaa agcttacctg caaatcatgg
    16561 gacatctcat taaaagtttg ccctaattgc tgaaattcta caggaccttg aacctccaaa
    16621 tttgaaggaa aatccttggc cgctacccgc ttggcatgct ccttgagttt gcccaacgac
    16681 gtaaagactg gcaataggag aaagagacta atcccagcac cgacaaggct ggcaacgatg
    16741 gtcatcccaa gcaaaaagta aatctcgcct ttcgcaatca gcattttttg aacagcccaa
    16801 aaaacaacca aaatggttaa gagggttgaa ataatatatc caaccaaaat ataacttttt
    16861 agtttcatgt ttgtcctctc ggtttctcta tcttatatcc caacccccaa actgtcttaa
    16921 tagtgggcgt ttggtcacta ctatattttg ccagctcctg tcgaagagca tggatatgca
    16981 cattcaaggt attggtgtca tccacgtagt cttctttcca gatcttttca tagaggtctg
    17041 tcttggagaa aactcgctct ggattgctag ctaaaatcca cagcaattca aatgatttaa
    17101 cagttaaatc cagcatttct tctcctattt gaacttcatg actactatga ttcattttta
    17161 gattgccaag ggaaatcagc tctgtttcgc ccccacgatg aaggcggcgc aaaatattgt
    17221 ggacacgcaa aaccagctca cgtgggctaa aaggcttagc aataaaatca tctgctccca
    17281 agctcaggcc gtaaatcttg tcctgttcac tggtcttagc agtaataaat aggaaaggct
    17341 gctctggtga taagtattga acctcactga ttaaatcata accatccatc cgaggcatca
    17401 tgacatctgt gataatcaaa tcaatcggtt ttttcttgaa cagctctagc gcttccagtc
    17461 catcatgggc taccaagacc tgataacctg cctgaattaa gtatctctga tgaatatctg
    17521 tgatttctac ctcgtcgtca acgagtaaaa ttgtctttcc catctgtctc tcctttgata
    17581 aaaacagtgc tatactgctt taagtataac actattttta ttgttttacg atgattttaa
    17641 tctgctattg aaagaaagtc ctgattgctg attgagttgt taaactaatc ttagtcagcc
    17701 cactatccat catttatttc cttagctgat tagttttctt cttttttgtt tttcaaacct
    17761 agaccaccga gtaaacctgc aagcgcaagc ccaaggaaac caatacttgc cattgatgtt
    17821 tgagtctcac cagtatttgg tagcatagct ttatcctctg acatcatcgt atcagacatc
    17881 ttgttagcag aagcagccat gttttcacct gccatcgtgt tggtagaact tgtcatggtg
    17941 tcagcaggca tgctatctgt agtacctgta gcatgattgt gattcatcgg agtcacgcca
    18001 gaaccagagt tagaaggtga taatgaacca tttgctgtgt ctgatgtttc tttaacattt
    18061 atcttaatag tgactttttt agttgctacg atgttgtcca agtctggttt accgtctttg
    18121 ttaccataga cattgactgt agcgctgtaa gtttgagtac c
//
LOCUS       DAVAGB010000042        17838 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVAGB010000042 DAVAGB010000000
VERSION     DAVAGB010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17838
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.042"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(160..363)
                     /locus_tag="VQO19_001616"
     CDS             complement(160..363)
                     /locus_tag="VQO19_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET1349848.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(356..1438)
                     /locus_tag="VQO19_001617"
     CDS             complement(356..1438)
                     /locus_tag="VQO19_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET1349849.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1564..2346)
                     /locus_tag="VQO19_001618"
     CDS             complement(1564..2346)
                     /locus_tag="VQO19_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HET1349850.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2346..3689)
                     /locus_tag="VQO19_001619"
     CDS             complement(2346..3689)
                     /locus_tag="VQO19_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HET1349851.1"
                     /translation="MNLKTTLGLLAGRSSHFILSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(3788..5104)
                     /locus_tag="VQO19_001620"
     CDS             complement(3788..5104)
                     /locus_tag="VQO19_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HET1349852.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQNLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAANLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5297..6523
                     /locus_tag="VQO19_001621"
     CDS             5297..6523
                     /locus_tag="VQO19_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HET1349853.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSASGKEKTDSLTQGMTANQALKS
                     NRFYILWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            6722..8296
                     /locus_tag="VQO19_001622"
     CDS             6722..8296
                     /locus_tag="VQO19_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET1349854.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LNEKQTGFVIRNKGDK"
     gene            8561..9349
                     /gene="codY"
                     /locus_tag="VQO19_001623"
     CDS             8561..9349
                     /gene="codY"
                     /locus_tag="VQO19_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HET1349855.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9349..9924
                     /locus_tag="VQO19_001624"
     CDS             9349..9924
                     /locus_tag="VQO19_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET1349856.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10006..10091
                     /locus_tag="VQO19_001625"
     tRNA            10006..10091
                     /locus_tag="VQO19_001625"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10040..10042,aa:Leu,seq:aag)
     gene            10375..11505
                     /gene="ugpC"
                     /locus_tag="VQO19_001626"
     CDS             10375..11505
                     /gene="ugpC"
                     /locus_tag="VQO19_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HET1349857.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            12006..12764
                     /locus_tag="VQO19_001627"
     CDS             12006..12764
                     /locus_tag="VQO19_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET1349858.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAIDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            12851..13363
                     /locus_tag="VQO19_001628"
     CDS             12851..13363
                     /locus_tag="VQO19_001628"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HET1349859.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13545..14489
                     /locus_tag="VQO19_001629"
     CDS             13545..14489
                     /locus_tag="VQO19_001629"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HET1349860.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            14498..15175
                     /locus_tag="VQO19_001630"
     CDS             14498..15175
                     /locus_tag="VQO19_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HET1349861.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELFFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            15273..16031
                     /locus_tag="VQO19_001631"
     CDS             15273..16031
                     /locus_tag="VQO19_001631"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HET1349862.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16069..17574
                     /gene="lytC"
                     /locus_tag="VQO19_001632"
     CDS             16069..17574
                     /gene="lytC"
                     /locus_tag="VQO19_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HET1349863.1"
                     /translation="MSVTFFIGEERLKIKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            complement(17663..>17838)
                     /locus_tag="VQO19_001633"
     CDS             complement(17663..>17838)
                     /locus_tag="VQO19_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000530076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET1349864.1"
                     /translation="NALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALN
                     IKKERTKFVLSQA"
BASE COUNT         5349 a         3200 c         3977 g         5312 t
ORIGIN      
        1 ctgtgcagta cagaactaaa tcctttggat aaattaattg tctaactttt ggggggcagt
       61 acattttaac acttgataat atgcgtttta ttgtgggaag attttcctca ttttctagtg
      121 aaattgaact ttttctaaca tcttttgata gatgacttct taatcaatta tcatttccat
      181 tgttgtttct tggggtttca tcccttgtct ttgataaaag cggagagcac cctcgttatc
      241 attccagaca cttagggtta gattattgca gccaatttct ttagcataat agcagaaaaa
      301 tgacaataaa atagccccta gatattttga aaggaaagca taggggctat atagtttaat
      361 caaaataaag caaatctttg ctggtgcttg taaagaggtc gaagccatcc ttggtaacaa
      421 caccgcagtc ttcaatacga acaccgactt taccagggat atagatacct ggttcaacag
      481 agaagcacat gccttcttcg atgaccatgt cgtttccttc catgatagat gggaattcat
      541 ggacatccat accgatacca tgcccgagac ggtggttgaa gtactcacca taaccagctt
      601 tttcgatgac ctcacgggca gcgcggtcca cttcatgagc agtcacacct ggcttgataa
      661 agtcaagagc agcttgttgg gcttcaagag tcaagttgta aatatctttc ttgaattggt
      721 ctggtttgcc gacagcgact gtacgagtca tatctgacgc atagccattg accagaacac
      781 ccaggtcaaa gaggagaaga gcatcatttt caaccttatt agctgctgga atgccgtgtg
      841 gattcgcagc attatcacca gtcaagacca tggtatcaaa gctcatttcg taaccttcac
      901 gtttcatggc aaagtcaatt tgtgcgatga tatctgtctc agtcttatca agagaaatat
      961 tgtcaaaacc aacatgaaca gccttgtcag cataaagacc tgcaaccatc attttttgca
     1021 cttcatcagc tgatttgatg aggcgcatgc gttggatacg aggagtgagg ttgtcaaact
     1081 cagcagtctc aaaaactgtt ttcaaaccat ggtatttggt caagatgaga ttgtcaaact
     1141 caacagcgac acgtttgaag tcaagttgtg gaagagcatg tttgattttt tgccatggat
     1201 tttcagaatc gacatagccc actactggga aggaaacggt gctacttgca cgttctactt
     1261 caagagctgg gacaaagagg agaggttcct gatccgctag gacaaagagg aacatttggc
     1321 gttcatgggg atcactgtaa aaaccagtga ggtaattgat tgtgacgggg tcagatacga
     1381 cagcgacgtc tagtttttct gattcaagat atgttaggat ttgttgtaat ttagacatat
     1441 gctaccttct ttctacccct ctattttggc aaaaaatgag agaaaatgca agggagaagg
     1501 gtaaaagaaa agacaaaaaa ctccgacaag ataacggagt tctttgatat cattttcctt
     1561 tgtttaagaa aagtcagcct tgcttttgac gtcactgtac tcttcagcga tttcttggct
     1621 gagaatgtcc tcataggcag ggagttggat gtcctgacca tatttcttct tgagggcagt
     1681 agtaactagg cgataagcca gattggcatt acgagagagg ataggcccgt ggaagtagga
     1741 accaaagaca ttcttataat gaaccccttc accgaccttt tcttcgttgt ttccatttcc
     1801 atagacaacc tgtcccagcg gtttttggtc atcagagagg aaggtacgac cttggtgatt
     1861 ttcaaatcca tagtaggttt catcgaaatc ttcattgtga atcttgatgt caccgataaa
     1921 acggttattg gtctggttga gcgtgtagtg tcccatgacc cctagccctt cgatacgttt
     1981 tcctgaagct tcaacataat attgacccaa tagttggaaa ccaccgcaga tagccagaac
     2041 tacaccgtcg ttttggatgt agttgtcaat gctctctttt ttagcaggta ggtcgtctgc
     2101 aatgatactt tgttcaaagt cttgaccacc accgaaaaag gcgatgtcgt agtgattttc
     2161 atcaaagtca tcatggagag aaacgatgtc aacggtcaca tgggctccca gtttttcagc
     2221 cacatacttg agcatgagga tgtttccatt gtccccgtag gtattcatga gatttccgta
     2281 gaggtgggca atgttgagct gataggggta attgctatct tttgaggaaa gtgaagtata
     2341 aaccattagt tcatctcctt tctaacaatc tgacgactag ccagcagttc acgaaattcc
     2401 agcatggcag tataagttgc cagaatatag gcatgcttgc agtcttgatt ctcaatggtc
     2461 ttgagaactt gctccagatt actcgtttca gtgattttct cagctggata gccagtcact
     2521 cggaggcgac gagcgatttc agaatgacga acaccgccag cgttgatttc aggaatgtcc
     2581 atgtcagtga tttgctcaaa gtctgcatcc cagatccagc tagtgtcaat tccatctgca
     2641 tagttggcat taaggaggac agataggcta aatggataag gtgctagttt gatcatttcg
     2701 atagcttggg ttgcaccgac tggattttta atcaagacaa gggtacattc cttgtcaccg
     2761 atatgaaagg tttcttggcg tccaaagaca gcacggctct tgtcaaatcc ctgtttgatg
     2821 agttgcgaat cggcacctag gaaacgggcg atggccacag cagctagggc gttatagata
     2881 ttatagagcc cgccgatttg gataccgtat tcttggccgt ctatgacaaa gcgagagcga
     2941 ttgttggtca actcaaccaa ttttgtcaaa cgatagtcga gatcaggacg tttacatcca
     3001 caaccttcac agatataggc acccaagttt gcataggtat tatgctcata tttgaggatg
     3061 ccttggcagt caggacagag aatcccttcg gtattgtagt gagccagttg ggctggtcct
     3121 ttttccaagt caaaaccaaa atactctata gggtttggaa tagttggctt gtagaaaagt
     3181 ggactgtctc cgttaaggag aacagtagca gttggaactt tccgaatggc atccaatatc
     3241 atgttatagg tagtatagat ttcaccgaaa cggtccatct ggtcacggaa gatattagta
     3301 atgacaaaaa gactaggctg gatatagtca cagatacgag atagactggc ttcgtcaatt
     3361 tcgaggacgg caatattttt tccagtttta gaagatttgg ctgttaggaa ggttgttgca
     3421 atccctgtaa tcatgttggc accgcttgga ttggttagaa cttgaccata gacctctttt
     3481 aaaatgccga cagtgagggc agttgtcagg gtttttccat ttgttccagt gacaacgaca
     3541 atctcgtagt tcttagctag gttttgtaaa atatctttat caaattgaag ggcgacttta
     3601 cctgggagcg tacttccacg gccaagacgg cttaaaatga agtgggaaga acgcccagca
     3661 agaaggccca aagtagtttt taagttcatg tttctattat atcataaaag aggagaaaga
     3721 cagatttgag attccgcaga agtaaaaaca gcccaaagag ggctgttcga tacgattaaa
     3781 tctcaactta aatcgcaaac aagtcattca agttctcagc caaggttggg tgagtgaaga
     3841 tttgttttgt gaagtaagtg taaggaatct tgttgtccat agcaacagta ataatgttga
     3901 tgatttcttg agaaccttct gagaagatgc ttgcaccaag aatttctttt gtttcagtat
     3961 taacaacagc tttgaaagct ccgcgaaggt ctccatttac gtgaccacga ggcatggctg
     4021 caacagggat ttctttcact gcgtatggaa gtttcaaatt agctgcttgg ctttcagtca
     4081 aaccaacttg tgaaagtgca ggtgtgatga acatagtatt tggcacattg agacggtcct
     4141 caagtgtgta gctgccatct ccagcaaggt agctgtaaac aacacggaag tcatcaagtg
     4201 aaatgtaagt aaattgaaga ccaccgttga catctccaac tgcaaagaca ccaggaacgt
     4261 ttgtttgaca gtgtttatct actttaatag cgccacgttc agttagttca atatctgtat
     4321 tttcaagttg aagtggttct acatttggtt tgcgtccagt tgcgtagaga agggcgtcga
     4381 aacggtaagt ttcgtcttca gttacgacaa gcacttggtc accgtcgttt ttaatttcag
     4441 tagtatggat attttgaagc aattcaatgc catcttcttc catgtattgt ttagcaagag
     4501 ctgcgatgga aggttctgca cgaggaagga aagtatccaa ggcatctagg actgtgacct
     4561 tgcttccaag tttgttgtaa aggccggcaa attcaagacc gatatttccg ccaccaagga
     4621 ttccaagttt ttcaggtaat ttgtccaagt tttggatacc tgttgagtca aagatgtttt
     4681 tgcttgtagc aagtccaggg attggcaaga cgtttgaaac agcaccagtg ttgatgacga
     4741 ttgtttcagc agtcagttct ttcttttcat caccagcttg gatttcgatg actttatttg
     4801 aaaggaagtg agcttccgca tcaaagatat ctacgcctgt accagcaaca gtcgcatagt
     4861 ttttaccgtt gaggcgacca gtgatcgtgt ttttagtagc aatcacttct tcaaaagaca
     4921 agtccttttc agcagcaact agcaaggttt tagttgggat acaaccaatg ttgatacaag
     4981 ttccaccgta catagccttg ctgcgttcaa cgagggcaac ttttttgcca gctgaagcca
     5041 atttacctgc tagtgtttta ccagctttac caaatccaat aacaattaaa tcgtatgtta
     5101 acatttatct tcctcctatt cgaatttcat tctagcacaa gaaaaaaact tttgcacaat
     5161 tctgctacgg aaaagacaga aaaagataaa aacgctttcc agacaaaaaa ctagtaattt
     5221 tttgacaagc ttgataaact aaaatcctat ctatttttat ataagataga ataaatgttc
     5281 gaaaatagga ggttttatga aatcgaatcg ttatattatt gcctttgctg gggtcatttt
     5341 acacttaatg ctgggttcga cttatgcttg gagtgtttat cgtaacccta ttattgaaaa
     5401 aacgggatgg gatcaggctt ctgttgcctt tgcctttagt ctagcaatct tttgtttggg
     5461 cttatcggct gcatttatgg ggcgtttggt agaaaaattt ggtccgagag tcatggggag
     5521 tctatctgct tttctatacg caggtggaaa tatcttaaca ggatttgcaa tagaccgtca
     5581 ggaactgtgg ttgttgtatc tagcttatgg cattttaggt gggcttggtt tgggagcagg
     5641 ctatattacc cctgtgtcaa cgattataaa atggtttcct gataaacgtg gtctcgcaac
     5701 aggtttagcg attatggggt ttggttttgc ttctttattg actagtccca tagcgcaaca
     5761 tctcatcgca ggggtagggc ttgtagaaac tttttatatt ttaggtgcaa gttactttat
     5821 tatcatgctc ctagcttcac aattcattaa gcgtccaaat gagcaagagc ttgcaatttt
     5881 atctgcttca gggaaagaaa aaacagactc tctgacgcaa gggatgactg caaatcaggc
     5941 tctaaaaagc aatcggtttt atatactttg gattattttc tttatcaaca tagcttgtgg
     6001 tttaggctta atttcagcgg catcgccaat ggcacaggag atggctggct tgtctacaag
     6061 tcatgcagca gtaatggtgg gcgttttagg gattttcaat ggatttggtc gcttgctctg
     6121 ggcgagctta tctgactata tcggtcgccc tctaaccttt agtatattac tgcttgttaa
     6181 tcttttcttt tctctctcac tttggctctt tacagattcc gttttatttg tagtcgctat
     6241 gtctattttg atgacttgct atggagctgg tttttcattg atcccagctt atctcagtga
     6301 tatttttgga accaaggaat tggccgctct gcatggatat attttaacag cttgggcaat
     6361 ggctggttta gcgggaccta ttttattagc agagacttat aaaatggctc attcgtacac
     6421 acaaaccttg ttcgtttttc tcattttata cagtatcgcc ttggctttgt cttattatct
     6481 aggtcgttca atcaaaaaag aaagtcaaaa accgcttaca tgattttctg tagaaatggg
     6541 gctatctttt gctctggtct tgtgttatac tagataggtt gcaaagaaaa cagtactttt
     6601 cttttgtgga aaagaagcaa cacgatttta tatctagtta tatgaaaata cgtcataaaa
     6661 agaaaagtat aaactaagcc ctatagggtg gcttcgcacc acctttagaa agaagaataa
     6721 cgtgaaattt aatgaattaa acttgtctgc tgatttgcta gcagaaattg aaaaagctgg
     6781 ttttgtagaa gctagtccta tccaagaaca aactattcct ttggcccttg aaggcaagga
     6841 tgttatcggt caagctcaga ctggtacagg aaaaactgca gcctttggct tgcctaccct
     6901 tgaaaaaatc cgtacagaag aagcgactat ccaagctttg gtcatcgctc caactcgtga
     6961 actagctgtc caaagtcaag aagaactctt ccgctttggt cgtagtaagg gagtcaaagt
     7021 ccgttcagta tatggcggat caagcattga aaaacaaatt aaggctctta aatctggtgc
     7081 ccatatcgtg gtgggaactc caggtcgcct cttggacttg attaaacgca aggccttgaa
     7141 attacaagac attgaaaccc ttatccttga cgaagcggat gaaatgctta acatgggctt
     7201 ccttgaagac atcgaagcca ttatttcccg tgtacctgag aaccgtcaaa ctttgctttt
     7261 ctcagcaact atgccagatg ccatcaaacg tatcggtgtt cagtttatga aagcccctga
     7321 acatgtcaag attgcggcta aggaattgac aacagaattg gttgaccagt actatatccg
     7381 tgttaaggaa caagaaaaat ttgacaccat gactcgtctc atggatgtgg cacaaccaga
     7441 actcgctatt gtatttggtc gtaccaaacg ccgtgtggat gaattgactc gtggtttgaa
     7501 aattcgtggc ttccgtgcag aaggaattca tggcgaccta gaccaaaaca aacgtcttcg
     7561 tgtccttcgt gactttaaaa atggcaatct tgatgttttg gttgcgacag acgttgcagc
     7621 gcgtggtttg gatatttcag gtgtgaccca tgtctacaac tacgatattc cacaagatcc
     7681 tgagagttat gttcaccgta tcggtcgtac aggtcgtgct ggtaagtcag gtcaatctat
     7741 tacttttgtt gctccaaacg aaatgggtta ccttcaaatc attgaaaact tgactaagaa
     7801 acgcatgaaa ggtctcaaac ctgcaagtgt agaagaatcc ttccaatcaa aaaaacaggt
     7861 agctctcaag aaaatcgaac gtgattttgc agatgaaacc attcgtgcca actttgagaa
     7921 atttggtaag gatgctcgca aattggctgc tgagtttact ccagaagaat tggcaatgta
     7981 tatcttgagt ctgacagtcc aagacccaga tagccttcca gaagtggaga ttgcacgtga
     8041 aaaaccacta ccgtttaaac catcaggtaa tggtttcggt ggtaaagcta agggaggtcg
     8101 tggaggccgt cgtggggatg accgtcgaga gcgtgatcgc cgtggcaatg gtcgccgtga
     8161 tgagttcaaa aaaggaagtc gtggcaacga tcgttttgat aaggaaaaac gttaccgtaa
     8221 ggataataaa aaaccacgca atactttaaa cgaaaagcaa acaggctttg ttattcgtaa
     8281 caaaggtgat aaataagaaa aagcggttca aaatgaatcg cttttttata taaggagacc
     8341 gaatgtgaaa aagacaaata aaattattat attatctttt ataatattat gatacaaaaa
     8401 aataggcaac ttgtcaatag aaaaggaaca atttaattaa aaatattctg gtttttaatt
     8461 aaattgtaag tcaatgcaag tcaataagga attttcagat aattattgaa aaagagacgt
     8521 ttttatgtta taatgatagc gattaaattc gaggtgaaaa atggcacatt tattagaaaa
     8581 aactagaaaa attacatcaa ttttgaaacg ctcagaggag cagttgcagg atgagcttcc
     8641 ttacaacgct attacgcgtc agttagcgga tattattcat tgcaatgcct gcattatcaa
     8701 tagtaaggga cgtctgcttg gctattttat gcgttataaa acaaatacag atcgcgtaga
     8761 gcaattcttc caaactaaga ttttcccaga tgactacgtt caaggggcta atatgattta
     8821 cgaaacagaa gcaaacttac ctgttgagca tgatatgagt attttccctg ttgagagtag
     8881 agatgatttt ccagatggct tgacgactat tgcaccgatt catgtatcgg ggattcgcct
     8941 tggttctttg attatttggc gtaatgataa aaaattcgaa gatgaggact tggttcttgt
     9001 tgagattgcc agtaccgttg ttgggattca gcttcttaac ttccaacgtg aagaagatga
     9061 gaaaaatatt cgtcgtcgta ctgctgtcac catggcggtc aatacccttt cttactccga
     9121 actccgtgct gtttcagcaa ttttagggga attaaatgga aatgaaggga agttgactgc
     9181 gtcagtgatt gcagatcgta tcggaatcac tcgctctgtg attgtcaatg ctcttcgtaa
     9241 acttgagtct gcggggatta ttgaaagtcg ctcacttgga atgaagggaa cctatcttaa
     9301 ggtcttgatt tcagatattt ttgaagaagt gaagaaaaga gattactaat gacaaaggct
     9361 ttaatttcga ttgattatac agaagatttt gttgctgata gtgggaaact aacagcaggt
     9421 gctccagctc aggcgatttc ggatgccatc agcaaggtaa ctcgattagc ttttgaacga
     9481 ggagattata tcttctttac tattgatgct catgaagaaa acgattgttt ccatccggaa
     9541 agtaagttat ttcctcctca taatctgatt gggacgagtg gacggaattt atatggagat
     9601 ttggggatct tttatcaaga gcatggttca gacagtcgtg tcttttggat ggataaacgc
     9661 cattactcag ctttttcagg gactgaccta gatattcgtt tgagagagcg tagagtgtct
     9721 accgttatct taacaggtgt cttgacggat atctgtgtcc tacatacagc tatagatgcc
     9781 tataatctag gatatgacat cgagattgtt aaaccagctg ttgcttccat ctggcctgaa
     9841 aatcatcaat ttgccctagg tcatttcaaa aatacactcg gagctaagtt agtagatgaa
     9901 aatctaaatg aactttctga gtaacctggt tggtgaaaat gaaaaaattt gaaaaaaagt
     9961 gttgacaagc atcccaaaag ttgatatact agtaaagtaa tcgacgcggg gatggcggaa
    10021 ttggcagacg cgcaggacta aggatcctgt gaccgcttta ggtcgtgagg gttcaagtcc
    10081 ctctctccgc ataggaaaag agctagctaa agctagctct tttgtatttc tctaaaaaat
    10141 tagaatccag tcaaatgtag tggagaatca gcgaaaatat gggaaaactg atccttgttt
    10201 ctgcttttgt ctatagaaga ataataaaga ttatcttctt caaattctcc gatattctct
    10261 aaagttttgt gcaagttgca cagaactttt ttattttttt ggtcatcttg ccatagaaat
    10321 ataaagcgtt ttcatctata atataattat caaaagacaa aaggagttca cctcatggta
    10381 gaattgaatc ttaaaaatat ttacaaaaaa tatccaaaca gcgaacacta ttcagttgaa
    10441 gatttcaact tgaacatcaa agataaagaa tttatcgttt tcgtaggacc ttcaggatgt
    10501 ggtaaatcaa ctacactccg tatgattgct ggtcttgaag acattacaga aggtactgca
    10561 tctatcgatg gcgtggttgt caacgacgta gctccaaaag accgtgatat cgccatggta
    10621 ttccaaaact acgctcttta cccacacatg actgtttatg acaacatggc tttcggtttg
    10681 aaattgcgta aatacagcaa agaagacatt aacaaacgtg ttcaagaagc agctgaaata
    10741 cttggattga aagaattctt ggaacgtaaa ccagctgacc tttcaggtgg tcaacgtcaa
    10801 cgtgttgcca tggggcgtgc gattgtccgt gatgcgaaag tattcttgat ggacgaacct
    10861 ttgtcaaact tggatgccaa acttcgtgta tcaatgcgtg ctgaaatcgc taaaattcac
    10921 cgtcgtatcg gagctacaac tatctatgta actcacgacc aaacagaagc gatgacactt
    10981 gcagaccgta tcgttattat gtcagctact aagaaccctg ctggtacagg tactatcgga
    11041 cgtgtagaac aaatcggtac tcctcaagaa gtttacaaaa atccagttaa caaattcgtt
    11101 gcaggattca tcggaagccc agctatgaac ttcatcaacg tgaaattggt tggtagcgaa
    11161 attgtttctg acggtttccg tttgaaagtg ccagaaggag cattgaaagt tcttcgtgaa
    11221 aaaggctacg aaggaaaaga attgatcttt ggtatccgtc cagaagacgt gaatgcagaa
    11281 cctgctttcc ttgaaacatt cccagactgt gttgtaaaag cgactatctc tgtatcagaa
    11341 ctgcttggtt cagaatctca cctttactgc caagttggta aagacgagtt tgttgcaaaa
    11401 gttgatgctc gtgactactt gcaaacaggt gcaacagttg agcttggatt tgacttgaac
    11461 aaagcacact tcttcgatgt agaaactgaa aaaacaatct actaaaataa ataaaattca
    11521 aagcactaca agaaaagata tctctttatc aattgtagtg gagagatatc agttaatcta
    11581 gggagagaaa caaaatgctt ctctcctttt tgctagggaa gtcatattat gcatctatat
    11641 tgtgatgctc tttaatactc ttcgaaaatc tcttcaaacc acgtcaacgt cgccttgccg
    11701 tacgtatgat tactgacttc gtcagtttta tctgcaacct caaagctgta ctttgagcag
    11761 cttacggcta gttttctagt tttctctttg atttccattg agtattattt gtgggtacca
    11821 tctacaagtg aagctatatg cgtaaactac gtgagcaatt gaattcgaac tagagaggta
    11881 ataataaatt tatgctatag ttatggtgac ttgtatgctt ttgattctag tttatcaaat
    11941 aatagattag aattgtcaga taatatcatt ttgtgttata atgaagaaaa aacagaggtg
    12001 ttcaaatgtc agaagcaggt cataagtttt tagcaaaatt ggggaaaaaa cgcttacgtc
    12061 caggtggaaa gcgtgccaca gattggttaa ttgcagaagg aggattttca aaagaaaaga
    12121 gaatactaga ggttgcgtgt aataggggaa ctacagcaat tgagttggca cagcgttttg
    12181 gttgcaagat aactgctatt gatatggatg ctcaagcttt agaagtggct aaaaaatctg
    12241 ctggaacggc aggtgttgct catttaatca gttttgaaag agcaaatgca atgaaacttc
    12301 cttatcaaga tgctagtttt gatattgtta taaatgaagc tatgctgact atgcaagccg
    12361 atcaagctaa gaaaaaatgt gtaatggaat atctaagggt attaaaacct ggaggtcttc
    12421 tcttgacaca tgatgtgctt cttaaggaag ctaaagagtc tatcagacag gaattatcac
    12481 aagcaattca tgtaaatgta ggtcctttaa ctcaagatgg ttgggaacag gtgatgatag
    12541 aatcaggtta ttgtgatgtg aaagcattga ctggtgaaat gacattaatg aaattatcgg
    12601 gtatgattta tgacgaaggt ttgctaggaa ctttgaaaat ttgtgtaaat gcttgtaaaa
    12661 aggagaatag aaagcagttt ttaactatgt ataaaatgtt tgctaagaat aaacagaaat
    12721 tgggctttat tgcgatggct agttataaat cgtcaaaacg ttagataatt attgaagtta
    12781 acttttcctt ttttctttct taaaaaatat gctataatag agagtaaaaa actttgaaag
    12841 aaagaaaaag atgaatttaa aagattacat tgcaacaatt gaaaattatc caaaggaagg
    12901 cattaccttc cgtgatatta gtcctttgat ggctgatgga aatgcttata gctacgctgt
    12961 tcgtgaaatc gttcagtatg ctactgacaa gaaagtcgac atgatcgtgg gacctgaagc
    13021 tcgtggattt atcgtgggtt gtccagttgc ctttgagttg ggaattggtt ttgcgcctgt
    13081 tcgtaagcca ggtaaattgc cacgcgaagt tatttctgct gactatgaaa aagagtacgg
    13141 tgtcgatacc ttgactatgc acgcggatgc cattaagcca ggtcaacgtg ttcttattgt
    13201 agatgacctt ttggcgacag gtggaactgt taaggcaact atcgagatga ttgaaaaact
    13261 tggtggtgtt atggcaggtt gtgccttcct tgttgaattg gatgaattga acggccgtga
    13321 aaaaattggt gactacgact acaaagttct tatgcattat taatgaaaac agtccctagg
    13381 gctgttttct ctacactagg atataaaaat agactataac tagttagaga aaaactataa
    13441 ttgaaaacta tatcttctta cagtataata aaaggactaa gtgtttgaga tttgtcttca
    13501 aacatatgca attattcctg aaagagtaca gttaggagag ggttatgccg attcgaattg
    13561 ataaaaaatt gccagctgtt gagattttac ggacagagaa tatctttgtc atggatgatc
    13621 aacgtgctgc ccaccaagat atccgtcctt tgaagatttt aattttaaat ctcatgccac
    13681 agaaaatggt cacagagacc cagttgttgc gccacttggc taatacaccc ctacaactgg
    13741 atattgattt tctctatatg gagagccacc gttctaaaac aactcgttca gagcacatgg
    13801 agaccttcta taaaactttt cctgaagtca aggatgagta ttttgatggg atgatcatca
    13861 cgggtgctcc agttgagcat ttaccatttg aggaagtgga ctattgggag gaatttagac
    13921 agatgcttga gtggtctaag actcatgtct attcgaccct tcatatctgt tggggggctc
    13981 aggctgggct ttatctgcgc tatggtgtag aaaaatacca gatggacagt aagctatcag
    14041 gtatttatcc tcaggacacc ctaaaagagg gtcaccttct atttagaggc tttgatgata
    14101 gctatgtatc ccctcattca cggcacacgg agatttctaa ggaagaggtc ttaaacaaga
    14161 ccaatctcga gattttatca gaaggacctc aggttggggt ttctattttg gccagtcgtg
    14221 atttacgaga aatttatagt tttggtcatt tggagtatga ccgtgatacc ttggcaaaag
    14281 agtattttcg agatcgtgat gcaggtttcg acccacatat tccagaaaat tactttaaag
    14341 atgatgatgt taatcaggta ccttgtcttt gttggtcttc atctgcagcc ctctttttca
    14401 gtaattgggt aaaccatgcg gtctatcagg agacgccttt tgattggaga aagatagaag
    14461 atgatgcatc tgcatatggg tatttataag aggaattatg acatatttag acgcttttaa
    14521 atcaggtacc ttggttttac cgagtgccct gctcttgcat tttaaggaac tctttccttc
    14581 tagcgacgat tttctggttt ggcaattttt ctatttgcaa aatacgacag gcttagaaga
    14641 aatgtcgcca agccagattg ctgaaaggat tggcaaggaa atttcggatg tcaaccagtc
    14701 catttctaat ctgacggaaa ggggactgct ccagtatcgt actatcgaat taaatggcga
    14761 aattgaattg ttctttgatg ctagtttggc cttggaacgt ttggatgacc tgtttggagc
    14821 agttcgttca agttcagacc agctaacacc tcaaaaccag ctcaaggatt tggtggaaac
    14881 cttccagcag gagttgggac gattgttgac gccttttgag attgaggatt tgaccaagac
    14941 actaaaggaa gatggaacca gtgctgactt gattaaggag gctcttcgtg aagctgtttt
    15001 gaatggaaaa ccaaactgga agtacattca ggcaattttg agaaactggc gccatgaagg
    15061 aatcaagagt gtggctcaaa ttgaggccaa gagagcagaa agagaagcaa gcaatcctca
    15121 gttgacacag gtatctgcag atttcagaaa tgccatggat ctctggaagg attaatccat
    15181 gcaagtaggc ttgaaatccg agtaagattt gcaagctgtg tataattgtg atagaataaa
    15241 tagaaaataa attgaaaaaa gaggtatgtg aaatgtcacg taaaccattt atcgctggta
    15301 actggaaaat gaacaaaaat ccagaagaag ctaaagcatt cgttgaagca gttgcatcaa
    15361 aacttccttc atcagatctt gttgaagcag gtatcgctgc tccagctctt gatttgacaa
    15421 ctgttcttgc tgttgcaaaa ggctcgaacc ttaaagttgc tgctcaaaac tgctactttg
    15481 aaaatgcagg tgctttcact ggtgaaacta gcccacaagt tttgaaagaa atcggtactg
    15541 attacgttgt tatcggtcac tcagaacgcc gtgactactt ccatgaaact gacgaagata
    15601 tcaacaaaaa agcaaaagca atctttgcga acggtatgct tccaatcatc tgttgtggtg
    15661 aatcacttga aacttacgaa gctggtaaag ctgctgaatt cgtaggtgct caagtatctg
    15721 ctgcattggc tggattgact gctgaacaag ttgctgcctc agttatcgct tatgagccaa
    15781 tctgggctat cggtactggt aaatcagctt cacaagacga tgcacaaaaa atgtgtaaag
    15841 ttgttcgtga cgttgtagct gctgactttg gtcaagaagt cgcagacaaa gttcgtgttc
    15901 aatacggtgg ttctgttaaa cctgaaaatg ttgcttcata catggcttgc ccagacgttg
    15961 acggtgccct tgtaggtggt gcgtcacttg aagctgaaag cttcttggct ttgcttgact
    16021 ttgtaaaata atcagtaagt agcaaaagct aggtggaaca gcattcagat gtctgttaca
    16081 ttttttatag gagaggaaag attgaaaata aaaattggat tagcaagtat ctgtttacta
    16141 ggcttggcaa ctagtcatgt cgctgcaaat gaaactgaag tagcaaaaac ttcgcaggat
    16201 acaacgacag cttcaagtag ttcagagcaa aatcagtctt ctaataaaac gcaaacgagc
    16261 gcagaagtac agactaatgc tgctgcccac tgggatgggg attattatgt aaaggatgat
    16321 ggttctaaag ctcaaagtga atggattttt gacaactact ataaggcttg gttttatatt
    16381 aattcagatg gtcgttactc gcagaatgaa tggcatggaa attactacct gaaatcaggt
    16441 ggatatatgg cccaaaacga gtggatctat gacagtaatt acaagagttg gttttatctc
    16501 aagtcagatg gggcttatgc tcatcaagaa tggcaattga ttggaaataa gtggtactac
    16561 ttcaagaagt ggggttacat ggctaaaagc caatggcaag gaagttattt cttgaatggt
    16621 caaggagcta tgatgcaaaa tgaatggctc tatgatccag cttattctgc ttatttttat
    16681 ctaaaatccg atggaactta tgctaaccaa gagtggcaaa aagtgggtgg caaatggtac
    16741 tatttcaaga agtggggcta tatggctcgg aatgagtggc aaggcaacta ctatttgact
    16801 ggaagtggtg ccatggcgac tgacgaagtg attatggatg gtgctcgcta tatctttgcg
    16861 gcttctggtg agctcaaaga aaagaaagat ttgaatgtcg gctgggttca cagagatggt
    16921 aaacgctatt tctttaataa tagagaagaa caagtgggaa ccgaacatgc taagaaaatc
    16981 attgatatta gtgagcacaa tggtcgtatc aatgattgga aaaaggttat tgatgagaac
    17041 gaggtggatg gtgtcattgt tcgtctaggt tatagcggta aagaagacaa ggaattggcg
    17101 cataacatta aggagttaaa ccgtctggga attccttatg gtgtctatct ctatacctat
    17161 gctgaaaatg agaccgatgc tgagaatgac gctaaacaga ccattgaact tataaagaaa
    17221 tacaatatga acctgtctta ccctatctat tatgatgttg agaactggga atatgtaaat
    17281 aagagcaaga gagctccaag tgatacagac acttgggtta aaatcatcaa caagtacatg
    17341 gacacgatga agcaggcggg ttatcaaaat gtgtatgtct atagctatcg tagtttatta
    17401 cagacgcgtt taaaacaccc agatatttta aaacatgtaa actgggtagc ggcctatacg
    17461 aatgctttag aatgggaaaa cccttattat tcaggagaaa aaggttggca atatacctct
    17521 tctgaataca tgaaaggaat ccaagggcgc gtagatgtca gcgtttggta ttaagcgatg
    17581 atttgaaaga gggatgtgat agtagcaccc tctttttctt tgttttatgg gctctttgtc
    17641 aactgtagtg ggttgaagtc agctaagctt gagaaaggac aaatttcgtc ctttcttttt
    17701 tgatgttcaa agcgataaaa atccgttttt tgaagttttc aaagtttcga aaaccaaagg
    17761 cattgcgctt gataagtttg atgagattat tggtcgcttc cagtttggca ttagaatagt
    17821 gtagttgaag ggcgttga
//
LOCUS       DAVAGB010000043        17599 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVAGB010000043 DAVAGB010000000
VERSION     DAVAGB010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17599
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.043"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(127..1062)
                     /locus_tag="VQO19_001634"
     CDS             complement(127..1062)
                     /locus_tag="VQO19_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HET1349865.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAGSLFKATAPITRNELIIEIWRTFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GFAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1059..1919)
                     /locus_tag="VQO19_001635"
     CDS             complement(1059..1919)
                     /locus_tag="VQO19_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET1349866.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2027..4189
                     /locus_tag="VQO19_001636"
     CDS             2027..4189
                     /locus_tag="VQO19_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HET1349867.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIYKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLEHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQFLSYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKNLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4281..5540
                     /locus_tag="VQO19_001637"
     CDS             4281..5540
                     /locus_tag="VQO19_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET1349868.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADDTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5554..6420
                     /locus_tag="VQO19_001638"
     CDS             5554..6420
                     /locus_tag="VQO19_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET1349869.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6434..7267
                     /locus_tag="VQO19_001639"
     CDS             6434..7267
                     /locus_tag="VQO19_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET1349870.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7578..9020
                     /gene="gtfA"
                     /locus_tag="VQO19_001640"
     CDS             7578..9020
                     /gene="gtfA"
                     /locus_tag="VQO19_001640"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HET1349871.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9158..10351
                     /locus_tag="VQO19_001641"
     CDS             9158..10351
                     /locus_tag="VQO19_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HET1349872.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11037..13016
                     /locus_tag="VQO19_001642"
     CDS             11037..13016
                     /locus_tag="VQO19_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET1349873.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13083..14579
                     /locus_tag="VQO19_001643"
     CDS             13083..14579
                     /locus_tag="VQO19_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET1349874.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14579..15505
                     /locus_tag="VQO19_001644"
     CDS             14579..15505
                     /locus_tag="VQO19_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET1349875.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15514..16581
                     /locus_tag="VQO19_001645"
     CDS             15514..16581
                     /locus_tag="VQO19_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1349876.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKEWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16592..17518
                     /locus_tag="VQO19_001646"
     CDS             16592..17518
                     /locus_tag="VQO19_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1349877.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQTELARYQKGLN"
BASE COUNT         5177 a         3129 c         3691 g         5602 t
ORIGIN      
        1 gttttaatga gagtttgtaa ctctcttttt tgtttttaga gacaataaaa cttcagatcc
       61 gtaaaactta attgaattac taatctgaag ttatttttat atcgtttata ttataattgt
      121 gttattttac ttccaactat tgagagaaat ttcgccacta tttagccaga tttcttttcc
      181 gttatcacat tgaactaaaa gttttccatt ttctgagatg tctttagcaa atcccttgta
      241 gtctttttgc tctagtgtga aagtgacttc ttttcctaga atgaatgact gttttttgta
      301 taggtataat agctcttctg ctggtgtttc gaagaaagta cgccagattt ctatgatcaa
      361 ttcattcctt gttataggag ctgtagcttt aaataagctg ccagcttttt cttttaattc
      421 ctgagggaag tctttaatag tgaaattgat acctactcca ataatgatat ctgtgactaa
      481 gccagtttct acagaggtca ttgcttcagt aaggattcct ccaattttat gattgtttag
      541 atagatatca ttgacccatt ttatgtcgac atctattaaa gttaggttct taatggcttt
      601 gtagacagct ccagctacaa gtagtgtgta ggatggtaat ttgtcatagg ggagatttgg
      661 tttaagatgg agtgtcatat aaataccacc ttgtggtgag tagaaggaac gttgaaaacg
      721 gcctcggcct gctgtttgat aggaagctag atagagggta tttgcttcat ggcctaaatc
      781 aattgcttct tttgcatcta gttgtgttga ttttgtttcg ggtttaaagc tgactttaat
      841 tggaagattt tcttctagaa tctctggaag aataaggtca ccattcatca gtttatatcc
      901 tctatttttg atactatcaa tttcaatgcc ttcttgttct agtcgcttga tggctttcca
      961 aattgatgtt cggcttaggg atagtttttc tgcgattttt tctccgctga tatagtcggt
     1021 ttctttagat aggatttggt agacagcttg gtaggatttc ataatgttgc ctttcttact
     1081 agttggtatt gagagtattc ttttcttgta tgacttggag tctgattaaa gtattgttta
     1141 taagctttcg aaaaatggag tggatctgaa aaacctaccg agtatgcaat taccttgatg
     1201 gactcttggg tattttcgag aagttgtcta gctcggtgca ttcgaacgta gagtaggtat
     1261 tctttgggtg ataaggtatt aaattctttg aatacgcttg ataagtagct tctgtgaacg
     1321 gatagttctt ttgctaaatc ttgaattgta agtgattgag gatagtggct atcaattaat
     1381 cgtttgcatt caagatagag ttggtgggtt gatgaaatat tctttttttt ctgattggga
     1441 gcaatagttc ccagatgaaa catcagttca tgaagttgtc ccatgatatg gagttgagct
     1501 aattcacttg attttgtaat ctgagcgaag cggacaatgt ctgagatgag ttttgcagta
     1561 gtctgggtat gacaagtttc agattggatg agataggatt gatcagaaat ttgagaaaga
     1621 gcaaaataat caggggattt ccctccagtg attcctaacc agtagtaggc ccaaggttct
     1681 ttactatctg cttgataaaa ggttagttcc tctggtttta atagaaagaa atctccttct
     1741 tttaaatcaa caattttacc cttgtaatga aattttcctt gtcctttagt aatgtaatgt
     1801 aggacgtatg tatcacgaat ggctggacca aaagagtaat taggtgtgca ttcctcatat
     1861 ccataaaagc ttagggcaag gtcgattgtt ccagtctggt attctgaaaa aactaacatg
     1921 tgctacctcc tacctaacat tttaccatat tcttgagaca tttttctatt ttagaaagcg
     1981 atttcaggtg ataaaatata atcaataaag tgatgaggtg aagtaaatgg gagttaggat
     2041 agagaataat ctattttatg ttgagagtaa aaatctaagt ttgattattg aaaatcgaaa
     2101 tggctactta cttttgaaac atttaggaaa gactattaag aactataaag gttccaatag
     2161 tgtttatgaa cgagaccatg ccttttcagg aaatccaaca gctactaatc gaacctttag
     2221 tttagatact caacgtcaaa tttttggaca acatggctta ggagatttta ggaaaccaac
     2281 catacaggtt cagcataatg taactgaagt aacagacttt cgatttgtag aagcaaagat
     2341 tttaaaaggt cagaatggtc cacagggctt accttctcca catagcatgg acgatacaga
     2401 gactcttgtc ttaatgttag aagattctaa ggctcaactt agtctgactt tgtattatac
     2461 tacttttaat aatgatgcga ctattgctag ctacagtaaa ttagataata atagtaatca
     2521 ggaagttgtc atctataaag atttttcttt tatggctgat tttccagctg cagattacga
     2581 aatagtaact ctgcagggtg cttatgctcg tgaaaagact gttagacgtc aacaggtaga
     2641 acaaggaatc ttttcgatta gttcaaaccg aggtgcttct ggtcatgctc aaacaccagc
     2701 tcttctacta tgcgaacaag gagtcacaga ggatgctggg aatgtgtttg ctattcaact
     2761 aatgtatagt ggcaactttg aagcttttgt tcaaaaaaat caattgaatg aagttcgggt
     2821 ggctattggc attaatccag aaaacttttc ttggaagtta gcccctgagg aatactttga
     2881 aacaccggta gctttagtga ctcattcaga tcagggatta actggtatta gtcatgaaag
     2941 tcagaatttt gtactggagc acattatgct aagtgaattt tctaaaaaag aacgtccaat
     3001 tctaatcaat aactgggaag ctacttactt tgactttcag agagaaaaac tgttagagtt
     3061 agcagatgaa gctaagaaag ttggcattga actttttgta ttagatgatg gttggtttgg
     3121 caatcgtttt gatgataatc gtgctttagg tgattgggtt gttaatgagg aaaaactggg
     3181 tggaagtcta gaaagtctga tttcagctat ccatgaaaga ggtttgcagt ttggactttg
     3241 gttagaaccc gaaatgattt ctgtagatag tgatttgtat cgtcaacatc ctgactgggc
     3301 tattcaggtt cctggctatg agcatactta ttctcggaat caattagtac ttaatcttgc
     3361 caatcctcag gtagtagaat acttgaaaag tgtcttagat caattcctat cttatcatga
     3421 tattgattac attaaatggg atatgaaccg caatatcact aagctaggga atggattaac
     3481 ttatctagag acacagatgc aatctcatca gtacatgctg gggctttacg aactcgtttc
     3541 ttatctgaca gagaagcaca gccatattct ctttgagtcc tgctctggtg gtggtggacg
     3601 aaatgatctt ggtatgatgc gctatttccc acaagtctgg gctagtgata atactgatgc
     3661 cattgcacgt ttaccaattc aatacggttc atcctatctc tatccaacca tttctatggg
     3721 ggctcatgtg tcagcagtac cgaatcatca gatgggacga atgacaccat tagaaacacg
     3781 tggccttgta gcaatgatgg gaaatttggg ctatgaactt gatttgacaa atttatcaga
     3841 tgaagagaaa gctacgattg ctaatcaggt gaacttgtat aaagaattac gaccagtagt
     3901 tcagttagga cagcagtata gactaattaa tcctgatact gtatccaatg aagcagctgt
     3961 acaatttaat tacggaaatc aaacgattgt aacctacgtt cgcgttttat ctgttgtaga
     4021 gaccatggaa acaactttaa aattaaaaaa tttggatgaa gagggactat ataaattaca
     4081 ggaaaatggc gaagtttact caggtgcaga actaatgtat gcgggcctaa ctgttatctt
     4141 atcccaagga gattttttga gtagacagta tatttttaga aaactatgat atgtactgac
     4201 ctcaaaagtt agatttattc tatctaactt ttgaggtgca gtttgataag ggtgtataaa
     4261 tttataaagg aggctttcta atggaatggt ataaaaaaat cggacttctt gcaactacag
     4321 gtttagcttt gtttgggctc ggtgcttgct ccaactatgg taaatctgcg gatgacacag
     4381 tgaccatcga gtatttcaac cagaaaaaag aaatgaccaa aaccttggaa gaaatcactc
     4441 gtgattttga gaaggaaaac cctaagataa aggtcaaagt cgtcaatgta ccaaatgctg
     4501 gtgaagtatt gaagacacgc gttctcgcag gagatgtgcc tgatgtggtc aatatttacc
     4561 cacagtccat cgaactgcaa gaatgggcaa aagcaggtgt ctttgaagat ttgagtaaca
     4621 aagactacct gaaacgcgtg aaaaatggct acgctgaaaa atatgctgta aacgaaaaag
     4681 tttacaacgt tccttttaca gctaatgctt atggaattta ctacaacaaa gataaattcg
     4741 aagaactggg cttgaaagtt cctgaaacct gggatgaatt tgaacagtta gtcaaagata
     4801 tcgttgctaa aggacaaaca ccatttggaa ttgcaggtgc agatgcttgg acactcaatg
     4861 gttacaatca attagccttt gcgacagcaa caggtggagg aaaagaagca aatcaatacc
     4921 ttcgttattc tcaaccaaat gccattaaat tgtcggatcc gattatgaaa gatgatatca
     4981 aggtcatgga catccttcgc atcaatggct ctaagcaaaa gaactgggaa ggtgctggct
     5041 ataccgatgt tatcggagcc ttcgcacgtg gggatgtcct catgacacca aatgggtctt
     5101 gggcgatcac agcgattaat gaacaaaaac cgaactttaa gattgggacc ttcatgattc
     5161 caggaaaaga aaaaggacaa agcttaaccg ttggtgcggg agacttggca tggtctatct
     5221 cagccaccac caaacatcca aaagaagcca atgcctttgt ggaatatatg acccgtccag
     5281 aagtcatgca aaaatactac gatgtggacg gatctccaac agcgatcgaa ggggtcaaac
     5341 aagcaggaga agattcaccg cttgctggta tgaccgaata tgcctttacg gatcgtcact
     5401 tggtctggtt gcaacaatac tggaccagtg aagcagactt ccataccttg accatgaact
     5461 atgtcttgac cggtgataaa caaggcatgg tcaatgattt gaatgccttc tttaacccga
     5521 tgaaagcgga tgtggattag gagtagagag actatgaaaa aagtattaca aaaatattgg
     5581 gcatgggctt ttgtggtcat ccccctcttg ttacaagcaa ttttcttcta tgtgccgatg
     5641 tttcaaggag ccttttacag ttttaccaac tggacaggat tgacttacaa ctacaaattt
     5701 gtcggcttaa acaactttaa gctcctcttc atggatccaa aattcatgaa tgcgattggc
     5761 tttaccgcaa tcattacgat tgccatggtg gttggtgaga ttgcactcgg gatcttcatt
     5821 gcgcgtgtct tgaactctaa aatcaaaggc caaaccttct tccgtgcttg gttcttcttc
     5881 ccagctgttt tatctggttt gacagtggct ttgatcttca agcaagtctt caactacggt
     5941 cttccagcga ttgggaatgc ccttcatatt gaatttctcc aaaccagtct tttagggact
     6001 aagtggggag caatctttgc ggctgtcttt gtccttcttt ggcaaggggt ggctatgccc
     6061 atcatcatct tcctagctgg tttgcaatct attccaactg agattacaga ggcagcaagg
     6121 attgatggtg cgactagcaa gcaagttttc tggaacattg aattgcctta cttgctacca
     6181 agtgtctcta tagtctttat cctagcccta aaaggtgggc tgactgcctt tgaccaagtc
     6241 tttgccatga ccggtggtgg tccaaacaat gccacaacct cacttgggct cttggtttat
     6301 aactatgcct ttaaaaacaa ccaattcggt tatgccaatg ccattgccgt aatcttgttc
     6361 ttcttaattg tagtgatttc gatcatccaa ttgagagtat ctaagaaatt tgaaatttaa
     6421 gaggagaagc atgatgaaac aagatgaaag aaaagccctg attggcaaat acattctatt
     6481 gattctagga tcggttctga ttttagtgcc gctccttgct accctcttta gttccttcaa
     6541 acccactaag gatattgtag ataatttctt tggctttcca accaacttca catgggacaa
     6601 ctttagccgt ctcttagctg atgggattgg aggctattat tggaactctg tcgtcatcac
     6661 tgtcttgtct ttacttgcag taatgatctt tatccctatg gcagcctact ccatcgctcg
     6721 caatatgagt aaaagaaaag cctttaccat catgtatacc ctcttaatcc tcggaatctt
     6781 cgtacctttc caagtcatca tgattccgat tacggttatg atgagtaaac tcggtttggc
     6841 taataccttt ggtttgatct tgctctactt gacctatgcg attccacaga ccctctttct
     6901 ctatgttggc tatatcaaaa tctcgattcc agaaagtctg gatgaagcag cagagatcga
     6961 tggggctaat caatttacaa cctatttccg catcatcttc ccaatgatga aaccgatgca
     7021 tgcgacaacc atgattatca atgccctttg gttctggaat gacttcatgt tgccactcct
     7081 tgtcttgaac cgggattcca aaatgtggac tctgcctttg ttccaataca actacgcagg
     7141 ccaatatttc aacgactacg gaccaagctt tgcctcttac gtggtcggca ttatcagtat
     7201 caccattgtc tatctcttct tccaacgcca tatcatttca ggaatgagca acggggcagt
     7261 gaagtaatac tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gctgtacttg
     7321 agtacggtaa ggtgaagctg acgtggtttg aagagatttt cgaatagtat aagaagagct
     7381 catggaatct atagtctttg acacagagga agagttcagc ttgttgataa ttctatgtag
     7441 aaaacaagaa agtagtactt tgtttatcac agtctatatt agtacgagtt tgatgataaa
     7501 tagagattta aaatgaattt tatttatgaa gccagatcat atgagacttg gcttcaatta
     7561 gaaaaaggag agtaatgatg ccaattcaaa ataaaaccat gttgattacc tattctgata
     7621 gccttggaaa taatcttaaa gacttatatg ataatttgga agagcatttt ggagatgcta
     7681 ttggaggagt tcacctttta ccatttttcc catcaacagg tgatcgtgga tttgcgccag
     7741 ttgactacga cgaagtggac tcagcttttg gtgattggga ggatgttaag cgtttaggtg
     7801 agagatatta tcttatgttt gattttatga ttaatcatat ttctcgtcaa tccaagtatt
     7861 ataaggacta tcaagaaaaa catgaagcca gtgaatttaa agatctcttt ttaaactggg
     7921 ataagttttg gccagaaaac cgtccgacac agtctgatgt agatttaatt tacaagcgta
     7981 aggatcgtgc accaaagcaa gagattgtgt ttgaagatgg ttcagtggaa catttgtgga
     8041 atacctttgg tgaggagcag attgatcttg atgtgaccaa agaagtaact atggaattta
     8101 tccgtaagac cattcagcac ttggcaagta atgggtgtga tttgattcgt ctagatgcct
     8161 ttgcttatgc agtgaagaaa ttggatacta atgatttctt tgtggaacca gatatttggg
     8221 atttattgga caaagttcga gatatcgctg ctgagtatgg gacagagctt ttacctgaga
     8281 ttcatgaaca ctattcgatt cagtttaaaa tagcagacca tgattactat gtttatgatt
     8341 ttgctcttcc aatggtgaca ctttatactc tttacagttc cagaacagag cgtttggcta
     8401 agtggttaaa gatgagcccg atgaagcaat ttacgacgct agatacccat gatgggattg
     8461 gagtagtaga tgtcaaggat atcctgaccg atgaggagat tgactatgct tcaaatgaac
     8521 tctataaggt tggagccaat gtcaaacgta agtactctag tgccgagtat aacaacttag
     8581 atatctacca aatcaattca acctactatt cagcgcttgg agatgatgat gtcaagtatt
     8641 ttctcgctcg tctaattcaa gcttttgccc caggtattcc tcaggtttac tatgtgggtc
     8701 tattagcagg caagaatgac ttgaaattat tagaagaaac taaagaaggt cgaaatatta
     8761 atcgtcatta ctatagcaac gaggaaatag caaaagaagt gcaacgacct gttgtgaagg
     8821 cccttctcaa tctattttct ttccgtaacc gttcagaagc ctttgatcta gaagggacta
     8881 ctgagataga gacaccaaca gctcacagca ttgtaatcaa acgtcaaaat aaagataagt
     8941 ccgtaacagc agtagcagaa attgatttgc aaaatcagac ttatcgggta attgagaatg
     9001 gagttgaagt aacattttga agccttgata tggtggataa aatagggttt ttattttgga
     9061 aaacgtttcc tttgttttca aattgctaaa aaagtggtac aatataggat agcttactat
     9121 tatctgaatc agctgatttg gagagaaagg attcattttg aaatcaatag gctttattga
     9181 aaagctgaag gggttgtcta gtaaagagct gattttattg ggaattatcc taagtatctt
     9241 tttacccttt tatctttttg tagttgtact ctgtttatat attatcagtt tgatttttac
     9301 aggagacatg aaaagtattc ttcagaaaat gggggagcat ccgatgctgc ttctttttct
     9361 tagctatagt actgttatat ccattcttgc acaaaattgg atgggtcttg tggcttcagt
     9421 aggaatgttt ctatttacta ttttcttttt gcactatcag tcgattttat cccataaatt
     9481 ctttcgattg attttgcagt tcgtcttgtt tggtagtgtc ttgtcagctg cttttgccag
     9541 tttagaacat ttccaaattg tgaagaaatt taactatgct tttctttcac ccaatatgca
     9601 ggtgtggcat cagaaccggg cagaagtgac cttctttaat cctaattatt atggaattat
     9661 ttgttgtttc tgtattatga ttgctttcta tctgtttaca acgaccaagt tgaattggtt
     9721 gaaagtattc tgtgtgattg caggctttgt taatctcttt ggtttgaact ttactcaaaa
     9781 tcgaactgcc tttcctgcta ttatcgctgg agcaattatc tatctcttta cgactattaa
     9841 aaactggaag gccttttggc ttagtattgg ggtcttcgcg attggtttga gtttcctctt
     9901 ttctagtgat ttgggagttc gaatgggtac tttagactct tctatggaag aacgcatttc
     9961 tatctgggat gctgggatgg ccttgtttaa gcaaaatcct ttttggggtg aagggccatt
    10021 gacctatatg cactcttatc ctcggataca tgctccttat catgaacatg cccacagtct
    10081 ttatattgat acgattctga gttacggaat tgtgggtacc attttattag ttctgtcttc
    10141 tgttgctcct gttcgcttga tgatggatat gagtcaggag tcggggaaac gtccgattat
    10201 cggcctttat ctatctttcc ttacagtggt tgctgtgcac ggaatttttg acttggctct
    10261 cttctggatt cagtcaggct ttattttctt gctagttatg tgcagtattc cattggagca
    10321 tcgaatgttg gtatcggaca tgacggatta agttttataa gtttgaaatc ttctaccttg
    10381 ggtaggagat tttttatacg atgggcatgt cgtggatctg aggtgtaagt cctctgtagg
    10441 gatccactac cggtgaatac aatagcgctc cccaagcctg actatcgtga ggtagcggat
    10501 taaaatggtc tggggataga tcgttttaag tctgacgcag gaaataagaa ttgtcagaga
    10561 aagcaatagt gaaatcgtag gctatgaata gaaacgtgat agcgaggagc atatagtgga
    10621 caaggtagcg agaaatttta aagtataaaa gatagtctta atctatatgt gtaaatcacg
    10681 aaagtaattg aattcggaat aaggttggtg tgaaaagaca tagtaaactg aatcttgaat
    10741 actagaatga tacttctaca atattgttat aatttaattt gaattccaaa atcacattgt
    10801 tccgtccgta tttcatttta ctgtatgtct tcctaagctc caaaatttct gtgtcaaatt
    10861 tcctattttc actgtagtct ttgacacttc gaacgacaat ttgaatcata tattcaaaaa
    10921 aaaatgaaaa atttgtgcca acaagcctaa atattctgaa aatttgtttg atttttaatg
    10981 gataatgtga tataatggtt gtcaatctat aattcacata aacagaggag tagaaaatga
    11041 aaaaaaatcg tgtatttgct acagcaggtc ttgttttatt agcagcaggt gtacttgcag
    11101 catgcagttc ttcaaaatca tctgattcat cagcccctaa agcttatggc tatgtttata
    11161 cagcagaccc agaaaccttg gactacctga tttcaagtaa aaatagtaca acagtagtga
    11221 cttcaaatgg gattgatggt ttattcacta acgataatta cggtaatctt gctcctgcag
    11281 ttgcagagga ttgggaagtc tctaaggatg gtttgaccta cacttataag attcgtaaag
    11341 gggttaaatg gtttacctct gatggagaag aatatgcaga ggtgacggct aaagatttcg
    11401 tgaacggttt aaaacacgca gcagataaaa aatcagaagc tatgtattta gctgaaaatt
    11461 cggttaaagg cttggcagat tatctatcag gaacttcaac agatttttca acagttggtg
    11521 tcaaggcggt tgatgattat acgttacaat acactttgaa ccagcctgaa ccgttctgga
    11581 actctaagtt gacctattct attttctggc ctctgaatga agaattcgaa acatcaaaag
    11641 gaagcgattt tgctaaacca acagatccga catccttgct ttataatggt ccattcttgt
    11701 tgaaagggtt gactgcaaaa tcttctgtag agtttgtaaa aaatgagcaa tattgggata
    11761 aagaaaatgt ccacctagat actatcaatc tagcttacta tgatggatca gatcaggagt
    11821 cgctagagcg taacttcact agtggagctt atagttatgc ccgtctttac cctaccagct
    11881 ccaactattc taaggttgca gaagaataca aggacaatat ctattacaca caatcaggct
    11941 ctgggattgc tggtctgggt gtgaatattg atcgccaaag ttacaactat acctctaaaa
    12001 ctacagattc agagaaagta gctactaaga aggcattgct taacaaagat ttccgtcaag
    12061 ccttgaattt tgctcttgat cgctcagctt actcagctca aatcaatggt aaagatggag
    12121 cagctttagc agttcgtaat ttatttgtaa aaccagactt tgtttcagct ggtgagaaga
    12181 cctttggtga tttagtcgct gctcaacttc ctgcttatgg tgatgagtgg aaaggtgtga
    12241 atttagctga tgggcaggat ggtttattca atgctgacaa ggccaaggca gagtttgcga
    12301 aagctaagaa agctttagaa gcagacggcg ttcagtttcc tattcatctg gacgttccag
    12361 tagaccaagc atcaaaaaac tacatatctc gtattcagtc ttttaaacaa tctgtagaaa
    12421 cagttcttgg tgttgaaaat gtcgttgttg atattcaaca aatgacaagt gatgaattcc
    12481 ttaatattac ttactatgct gccaatgctt catctgagga ttgggatgta tcaggaggag
    12541 tttcatgggg tccagactat caagacccat ctacttacct ggatatttta aaaacaacta
    12601 gcagtgaaac tacaaaaaca tatttaggat ttgataatcc aaatagccct tcagtagttc
    12661 aagttggttt gaaagaatac gataaattag ttgatgaagc tgccagagag acaagcgact
    12721 tgaatgtccg ttatgaaaaa tatgcagcgg ctcaagcatg gttgacagat agttcactct
    12781 ttattcctgc tatggcttct tctggtgcag caccagtgct ttcacgaatt gttccattta
    12841 ctggagcttc tgcgcaaaca ggctctaagg ggtcagatgt ttacttcaaa tatttgaaat
    12901 tacaagataa agtggtgact aaggaagagt atgaaaaagc tcgtgaaaaa tggttgaaag
    12961 aaaaagctga atcaaatgag aaagctcaaa aagaattggc aagtcatgtg aagtaaataa
    13021 tttctaatag aactttctct ccatgaggag aaggttcttt tgggattttt aaaggaaata
    13081 atatgaaaaa atatattttt atgcgtgttt tgcggtcatt ggtttcgatt ttcttagtaa
    13141 cgactttgac ctacacgatt atctatacct tggttcctcg aaaattgatt ttcaagcagg
    13201 atcctaacta taataaaatt gcgacaacgg ctgataaacg tgataactat gaaaatactg
    13261 tgtttgagcg tatgggctac attgagtatt acgatactaa agagttgcaa gaaaaggcaa
    13321 gtagcatgga ttcttctgta acagtagaag caaatgcgac taataaagct atttatgaaa
    13381 agtacatcaa tcaattaggt catggttgga ctttgggaga atttactgaa agtggtcaat
    13441 tctatgctac tcgtgaaatt ccaatttttg aacgtgtttt tcacttctat gctaacttga
    13501 ttgacattga ccatacaaat aaaatccaag accctgaaaa tccagacttg aaacgctacc
    13561 ttcgttttga aaatgatcca gctatcggat ggtcattggt cggttcagga actaaacata
    13621 aatatctctt gtactttaac agtcagttcc catttgttca tcaaaacttt gtgaacttga
    13681 atttaggtga ctcttaccca acctatgcta atacaccagt tcttcaggtt attactcaag
    13741 gtcaaggaca aaccaaaact gcccaagttc agttcccaac aggtaagaaa acgtcttctg
    13801 taaatattta ctcaagaacc tacaagtcac ctagtcaggc tgactctcgt gaagtagcta
    13861 gctatgggaa agatgatcct tatacagcga ctgaaagtaa ttaccaatat ccatctatga
    13921 ttgtcagctc tgctattact ggtttgattg gtttggttct tgcctatgct cttgccgtgc
    13981 cacttggttc agccatggct cgtttcaaga acacttggat tgatagcctc tcaacaggga
    14041 ctttgacctt cttgcttgct cttccaacga ttgccttggt ttacatcgtt cgattgattg
    14101 gatcatctat tgcccttcca gattcattcc ctatcttggg agctggagat tggcgttctt
    14161 acgttttacc agcagtcatc cttggtttgt tgggtgctcc tgttacagcc atttggattc
    14221 gtcgttacat gattgacttg caatctcaag actttgttcg tttcgctcgt gcaaaaggtt
    14281 tgtctgaaaa agaaatttca aacaaacaca tctttaaaaa tgccatggtt ccgctggttt
    14341 caggaattcc tggtgccatt attggggtta tcggtggtgc aacccttact gaaacagtct
    14401 tcgccttccc aggtatgggt aaaatgttga ttgactctgt aaaagcatct aataactcta
    14461 tggtcgttgg tcttgtcttc atctttacat gtatttctat cttctcacgt cttttgggag
    14521 atatttggat gactattatt gacccacgta ttaaattgac tgagaaagga ggcaaataat
    14581 gtctacaatc gataaagaaa aatttcagtt tgtaaaacgt gacgattttg cctctgaaac
    14641 tattgatgcg ccagcatatt cttactggaa atcagtgttt aaacaattta tgaagaaaaa
    14701 atcaactgta gtcatgttgg gaatcttggt agccatcatt ttgataagtt tcatctaccc
    14761 aatgttttct aagtttgatt tcaatgatgt cagcaaggta aacgacttta gtgttcgtta
    14821 tatcaagcca aatgcggagc attggttcgg tactgacagt aacggtaaat cgctctttga
    14881 cggtgtctgg ttcggagctc gtaactccat cctcatttct gtgattgcga cagtgattaa
    14941 cttggttatc ggtgtttttg tcggtggtat ttggggtatt tcaaaatcag ttgaccgtgt
    15001 catgatggaa gtttacaacg tcatctcaaa catcccacct cttttgattg ttattgtctt
    15061 gacttactca atcggagctg gattctggaa tctgattttt gccatgagcg taacaacatg
    15121 gattggtatt gccttcatga tccgtgtgca aatcttgcgc tatcgtgact tggaatacaa
    15181 cttggcgtca cgtactttgg gaacaccaac cttgaagatt gttgccaaaa atatcatgcc
    15241 tcaattggta tctgttattg tgacaaccat gactcaaatg cttccaagct ttatctcata
    15301 cgaagccttc ttgtctttct tcggtcttgg attaccgatt acagtgccaa gtttgggtcg
    15361 tttgatttcg gattattcac aaaacgtaac aaccaatgct tacttgttct ggattccatt
    15421 gacaaccctt gtcttggtat ccttgtccct tttcgtagtt ggtcaaaact tagcggatgc
    15481 tagtgatcca cgtacacata gataggagta gaaatgacaa aagaaaaaaa tgtaattttg
    15541 actgctcgcg atattgtcgt ggaatttgac gttcgtgaca aagtattgac agccattcgc
    15601 ggcgtttccc ttgaactagt tgaaggagaa gtattagcct tggtaggtga gtcaggatca
    15661 ggtaaatctg ttttgacaaa gaccttcaca ggtatgctcg aagaaaatgg tcgtattgcc
    15721 caaggtagta ttgactaccg tggtcaggac ttgacagctt tatcttctca caaggagtgg
    15781 gaacaaattc gtggtgctaa gattgcgact atcttccagg acccaatgac tagtttggac
    15841 cccattaaaa caattggtag tcagattaca gaagttattg taaaacacca aggaaaaaca
    15901 gctaaagaag cgaaagaatt ggccattgac tacatgaata aggttggcat tccagacgca
    15961 gatagacgtt ttaatgaata cccattccaa tattctggag gaatgcgtca acgtatcgtt
    16021 attgcgattg cccttgcctg ccgacctgat gtcttgatct gtgatgagcc aacaactgcc
    16081 ttggatgtaa ctattcaagc tcagattatt gatttgctaa aatctttaca aaacgagtat
    16141 catttcacaa caatctttat tacccacgac cttggtgtgg tggcaagtat tgcggataag
    16201 gtagcggtta tgtatgcagg agaaatcgtt gagtatggaa cggttgagga agtcttctat
    16261 gaccctcgcc atccatatac atggagtctc ttgtctagct tgcctcagct tgctgatgat
    16321 aaaggggatc tttactcaat cccaggaaca cctccgtcac tttatactga cctgaaaggg
    16381 gatgcttttg ccttgcgttc tgactacgca atgcagattg acttcgaaca aaaagctcct
    16441 caattctcag tatcagagac acattgggct aaaacttggc ttcttcatga ggatgctcca
    16501 aaagtagaaa aaccagctgt gattgcaaat ctccatgata agatccgtga aaaaatggga
    16561 tttgcccatc tggctgacta ggaggaagga aatgtctgaa aaattagtag aaatcaaaga
    16621 tttagaaatt tccttcggtg aaggaagtaa gaagtttgtc gcggttaaaa atgctaactt
    16681 ctttatcaac aagggagaaa ctttctcgct tgtaggtgag tccggtagtg ggaaaacaac
    16741 tattggtcgt gctatcatcg gtctaaatga tacaagtaat ggagatatca tttttgatgg
    16801 tcaaaagatt aatggtaaga aatcgcgtga acaagctgcg gaattgattc gtcgaatcca
    16861 gatgattttc caagaccctg ccgcaagttt gaatgaacgt gcgactgttg attatattat
    16921 ttctgaaggt ctttacaatc accgtttatt taaggatgaa gaagaacgta aagagaaagt
    16981 tcaaaatatt atccgtgaag taggtcttct tgctgagcac ttgactcgtt accctcatga
    17041 attctcaggc ggtcaacgtc aacgtatcgg tattgcccgt gccttggtca tgcaaccaga
    17101 ctttgttatt gcagatgagc caatttcagc cttggacgtt tctgtacgtg cccaagtctt
    17161 gaacttgctc aaaaaattcc aaaaagagct cggcctgacc tatctcttca tcgcccatga
    17221 cttgtcggtt gttcgcttta tttcagatcg tatcgcagtt atttacaagg gtgttattgt
    17281 agaggttgca gaaacagaag aattgtttaa caatccaatt cacccatata ctcaagcctt
    17341 gctttcagcg gtaccaatcc cagatccaat cttggaacgt aagaaggtct tgaaggttta
    17401 cgacccaagt caacacgact atgagactga taagccgtct atggtagaaa tccgtccagg
    17461 tcactatgtt tgggcgaacc aaaccgaatt ggcacgttat caaaaaggac taaactagta
    17521 atggttttat aatttccatg tcaattttta tggaaattag gctctttgtc aactgtagtg
    17581 ggttgaagtc agctaagct
//
LOCUS       DAVAGB010000044        16422 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVAGB010000044 DAVAGB010000000
VERSION     DAVAGB010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16422
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.044"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            <1..937
                     /gene="lytB"
                     /locus_tag="VQO19_001647"
     CDS             <1..937
                     /gene="lytB"
                     /locus_tag="VQO19_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HET1349878.1"
                     /translation="QAWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNKNAAYYQV
                     VPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDA
                     SKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLYFDGFKLENPFL
                     FKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALES
                     NWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLG
                     NKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(998..2653)
                     /gene="pavA"
                     /locus_tag="VQO19_001648"
     CDS             complement(998..2653)
                     /gene="pavA"
                     /locus_tag="VQO19_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HET1349879.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     ILNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2758..3255
                     /gene="ybeY"
                     /locus_tag="VQO19_001649"
     CDS             2758..3255
                     /gene="ybeY"
                     /locus_tag="VQO19_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HET1349880.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3236..3631
                     /locus_tag="VQO19_001650"
     CDS             3236..3631
                     /locus_tag="VQO19_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HET1349881.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3648..4547
                     /gene="era"
                     /locus_tag="VQO19_001651"
     CDS             3648..4547
                     /gene="era"
                     /locus_tag="VQO19_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HET1349882.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEKEY"
     gene            4595..5419
                     /gene="mutM"
                     /locus_tag="VQO19_001652"
     CDS             4595..5419
                     /gene="mutM"
                     /locus_tag="VQO19_001652"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HET1349883.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5419..6024
                     /locus_tag="VQO19_001653"
     CDS             5419..6024
                     /locus_tag="VQO19_001653"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HET1349884.1"
                     /translation="MRKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            6011..7210
                     /locus_tag="VQO19_001654"
     CDS             6011..7210
                     /locus_tag="VQO19_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HET1349885.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSIMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7210..7359
                     /gene="rpmG"
                     /locus_tag="VQO19_001655"
     CDS             7210..7359
                     /gene="rpmG"
                     /locus_tag="VQO19_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET1349886.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7399..7632
                     /gene="secG"
                     /locus_tag="VQO19_001656"
     CDS             7399..7632
                     /gene="secG"
                     /locus_tag="VQO19_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HET1349887.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7734..10088
                     /gene="rnr"
                     /locus_tag="VQO19_001657"
     CDS             7734..10088
                     /gene="rnr"
                     /locus_tag="VQO19_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HET1349888.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEAKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKKYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERIIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLCIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGCSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKL
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10051..10518
                     /gene="smpB"
                     /locus_tag="VQO19_001658"
     CDS             10051..10518
                     /gene="smpB"
                     /locus_tag="VQO19_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HET1349889.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10534..11394
                     /gene="tehB"
                     /locus_tag="VQO19_001659"
     CDS             10534..11394
                     /gene="tehB"
                     /locus_tag="VQO19_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HET1349890.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIGQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11467..12420
                     /gene="coiA"
                     /locus_tag="VQO19_001660"
     CDS             11467..12420
                     /gene="coiA"
                     /locus_tag="VQO19_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HET1349891.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQYFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12439..14241
                     /gene="pepF"
                     /locus_tag="VQO19_001661"
     CDS             12439..14241
                     /gene="pepF"
                     /locus_tag="VQO19_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET1349892.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYNFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKIGLA"
     gene            14243..14956
                     /locus_tag="VQO19_001662"
     CDS             14243..14956
                     /locus_tag="VQO19_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HET1349893.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGSLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            15023..15964
                     /gene="prsA"
                     /locus_tag="VQO19_001663"
     CDS             15023..15964
                     /gene="prsA"
                     /locus_tag="VQO19_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HET1349894.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKSNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16083..>16422)
                     /locus_tag="VQO19_001664"
     CDS             complement(16083..>16422)
                     /locus_tag="VQO19_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET1349895.1"
                     /translation="VGTAFKEKHYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRK
                     GNSQDNGRMESFFGILKSEMFYGYEQTFKSLNQLEQAIIDYIDYYNNKRIKIKLKGLS
                     SVQYRTKSFG"
BASE COUNT         4937 a         3078 c         3680 g         4727 t
ORIGIN      
        1 tcaagcctgg tactacttca aatctggtgg ctacatggcg aaaaatgaga cagtagatgg
       61 ttatcagctt ggaagcgatg gtaaatggct tggaggaaaa gctacaaata aaaatgctgc
      121 ttactatcaa gtagtgcctg tcacagccaa tgtttatgat tcagatggtg aaaagctttc
      181 ctatatatcg caaggtagtg tcgtatggct agataaggat agaaaaagtg atgacaagcg
      241 cttggctatt actatttctg gtttgtcagg ctatatgaaa acagaagatt tacaagcgct
      301 agatgctagt aaggacttta tcccttatta tgagagtgat ggccaccgtt tttatcacta
      361 tgtggctcag aatgctagta tcccagtagc ttctcatctt tctgatatgg aagtaggcaa
      421 gaaatattat tcggcagatg gcctgtattt tgatggtttt aagcttgaga atcccttcct
      481 tttcaaagat ttaacagagg ctacaaacta cagtgctgaa gaattggata aggtatttag
      541 tttgctaaac attaataata gccttttgga gaacaagggc gctactttta aggaagccga
      601 agaacattac catatcaatg ccctttatct ccttgcccat agtgccctag aaagtaactg
      661 gggaagaagt aaaattgcca aagataagaa taatttcttt ggcattacag cctatgatac
      721 gaccccttac ctttctgcca agacatttga tgatgtggat aagggaattt taggtgcaac
      781 caagtggatt aaggaaaatt atatcgatag gggaagaact ttccttggaa acaaggcttc
      841 tggtatgaat gtggaatatg cttcagaccc ttattggggc gaaaaaattg ctagtgtgat
      901 gatgaaaatc aatgagaagc taggtggcaa agattagtac tataagtgaa tatgatttga
      961 gtgaatagta agttaaaaat cctgatttca agtaaaatca ggattttttc atggatgcaa
     1021 tttttttgga gtctggtgtg acgcggaggg tcttttgtcc tgtgtaagtg acaaagccgg
     1081 gttttccacc agttggttta ttgagttttt tgacttcaat catatctacc tgcaccagat
     1141 tcgacaggcg cccttgagag aagtaggcag ctaactctgc tgcgtctgtc ttgactgcat
     1201 cagatgggtc aagatttcct gagatgacaa catggcttcc aggaatgtcc ttagcatgga
     1261 accaaagttc ctccttgcgg gccattttaa aggtcaattc ctcattttga agattgtttc
     1321 gtccgacata gatgatggtt ttgccatcgc ttgctagata ttgttctagt tttttgcgtt
     1381 tctggatttt ctcccgttgt cttctgcgga taaaacctgt ttgaatcaat tcttcgcgga
     1441 tttcagcgat ttcttccagt ccagcttggt tgaggatggt ttctacactt tccagataga
     1501 gaatagtggc tttggtttct tcaatcaaat cagtcaagta tttgacagct tctttgagtt
     1561 tctgataccg tttaaaatag cgttgggcat tctggttggg agtcagagcc ttatcaagcg
     1621 caatcatgat aggttggttg gtatagtagt tgtctaggat aacctggtct tggtcgttag
     1681 gcacttggtg taggaaggtt gtcagcaatt ctcctttttg acgaaattct tcagcgttgt
     1741 ctgtcgccag taactctttt tcctgttttt tgagtttgtg tcggtttttc tgaagttcat
     1801 tttcaacacg acgaatcagt tcactggcct gctgtttgac gcggtcgcgc tcagccttat
     1861 ccttatagta ggtgtccaac aaatcagaaa gatttgcaaa aggctctccc acctgatttg
     1921 caaaaggaac tggactgaag gaagtctcag tcaagcatgg cttggtttcc tgattgaaaa
     1981 aatttcggaa agcggaaagt ttttcactaa ccagtatcct ttccaattca tttgccgtat
     2041 cgcgtcccag accttgaaag aggctttgaa gattttttgc tgttagttct tgggtttgca
     2101 ggatttcaaa gagcttttca tccttgatag taaaaggatt gagagattct gtacttggcg
     2161 gagcgatata ggtcgatcct ggaagtaagg tgcggtagct attttgtgaa aagccgacgt
     2221 gtttgataac ttcgaggatt ttatgactgc ttttatcgac cagtagaata ttactgtgtt
     2281 tccccataat ttcgataatc aaggtagcct ggatatggtc tccaatctcg tttttattgg
     2341 aaactgtaat ttccacaata cggtcatttt ccacttgctc aatcgactca atcagggccc
     2401 cctgcaaata ctttctcaaa accatgataa aggtagaagg ttgggctgga ttttcaaaag
     2461 tcgtttgggt cagctgaatg cgtccaaaaa ctggatgggc agaaaggagc aggcgatggc
     2521 tttggcgatt gctgcggatt tgcaagacca actcttgttc aaaaggctga ttgattttct
     2581 ggatgcgacc attcactaat tcgcttcgca attcctcaac tatgtggtgt aaaaaaaatc
     2641 cgtcaaatga catcgttccc tccttgtgat tgtattccat agtattatat caaaaaggta
     2701 gaataaaatc atggaaatgt ggtataataa agccaagtaa agagaaacga gaagcacatg
     2761 tatattgaaa tggtagatga aactggtcaa gtttcaaaag aaatgttgca acaaacccaa
     2821 gaaattttgg aatttgcagc ccaaaaatta ggaaaagaag acaaggagat ggcagtcact
     2881 tttgtgacca atgagcgtag tcatgaactt aatctggagt accgtgacac cgaccgtccg
     2941 acagatgtca tcagccttga gtataaacca gaattggaaa ttgcctttga cgaagaggat
     3001 ttgcttgaaa atccagaatt ggcagagatg atgtctgagt ttgatgccta tattggggaa
     3061 ttgttcatct ctatcgataa ggctcatgag caggccgaag aatatggtca cagctttgag
     3121 cgtgagatgg gcttcttggc agtacacggc tttttacata ttaacggcta tgatcactat
     3181 actccggaag aagaagcgga gatgttcggt ttacaagaag aaattttgac agcctatgga
     3241 ctcacaagac aataaacgaa aatggaaaaa tcgtgacttg atatccagtt tagaatttgc
     3301 catcacaggg atttttactg ctatcaagga agaacgaaat atgcgaaaac atgcagtgac
     3361 ggctctagtg gtcatccttg caggttttgt ttttcaggtg tcacgaatcg aatggctctt
     3421 tcttctattg agtattttct tggtagtagc ctttgagatt atcaactctg ctattgaaaa
     3481 tgtggtggat ttggccagtc actatcactt ttccatgctg gctaaaaatg ccaaggatat
     3541 ggcggccggc gcggtattag tggtttctct tttcgcagcc ttaacaggcg cattgatttt
     3601 tctcccacga atctgggatt tattatttta aacagtaaga ggaaattatg acttttaaat
     3661 caggctttgt agccatttta ggacgtccca atgttgggaa gtcaaccttt ttaaatcacg
     3721 ttatggggca aaagattgcc atcatgagtg acaaggcgca gacaacgcgc aataaaatca
     3781 tgggaattta cacgactgat aaggagcaaa ttgtctttat cgacacacca gggattcaca
     3841 aacctaaaac agctctcgga gatttcatgg ttgagtctgc ctacagtacc cttcgcgaag
     3901 tggacaccgt tcttttcatg gtgcctgctg atgaagcgcg tggtaagggg gacgatatga
     3961 ttatcgagcg tctcaaggct gccaaggttc ctgtgatttt ggtggtgaat aaaatcgata
     4021 aggtccatcc agaccagctc ttgtctcaga ttgatgactt ccgtaatcaa atggacttta
     4081 aggaaattgt tccaatctca gcccttcagg gaaataacgt gtctcgtcta gtggatattt
     4141 tgagtgaaaa tctggatgaa ggtttccaat atttcccgtc tgatcaaatc acagaccatc
     4201 cagaacgttt cttagtttca gaaatggttc gcgagaaagt cttgcaccta actcgtgaag
     4261 agattccgca ttctgtagca gtagttgttg actctatgaa acgagacgaa gagacagaca
     4321 aggttcacat ccgtgcaacc atcatggtcg agcgcgatag ccaaaaaggg attatcatcg
     4381 gtaaaggtgg cgctatgctt aagaaaatcg gtagcatggc ccgtcgtgat atcgaactca
     4441 tgctaggaga caaggtcttc ctagaaacct gggtcaaggt caagaaaaac tggcgcgata
     4501 aaaagctaga tttggctgac tttggctata atgaaaaaga atactaagta gaggtgggct
     4561 catgcctgct tcttgtttta cagaaggagg acttatgcct gaattacctg aggttgaaac
     4621 cgtttgtcgt ggcttagaaa aattgattat aggaaagaag atttcgagta tagaaattcg
     4681 ctaccccaag atgattaaga cggatttgga agagtttcaa agggaattgc ctagtcagat
     4741 tatcgagtca atgggacgtc gtggaaaata tttgcttttt tatctgacag acaaggtctt
     4801 gatttcccat ttgcggatgg agggcaagta tttttactat ccagaccaag gacctgaacg
     4861 caagcatgcc catgttttct ttcattttga agatggtggc acgcttgttt atgaggatgt
     4921 tcgcaagttt ggaaccatgg aactcttggt gcctgacctt ttagacgcct actttatttc
     4981 taaaaaatta ggtcctgaac caagcgaaca agactttgat ttacaggtct ttcaatctgc
     5041 ccttgccaag tccaaaaagc ctatcaaatc ccatctccta gaccagacct tggtagctgg
     5101 acttggcaat atctatgtgg atgaggttct ctggcgagct caggttcatc cagctagatc
     5161 ttcccagact ttgacagcag aagaagcgac agctattcat gaccaaacca ttgctgtttt
     5221 gagccaggct gttgaaaaag gcggttccac cattcggacc tataccaatg cctttgggga
     5281 agatggaagc atgcaggatt ttcatcaggt ctatgataag actggtcaag aatgtgtacg
     5341 ctgtggtacc atcattgaga aaattcaact aggcggacga ggcacccact tttgtccaaa
     5401 ctgtcaaagg agggactgat gagaaaaatc atcggaatca ctgggggaat tgcctctggt
     5461 aagtcaactg tgacaaattt tctaagacag caaggctttc aagtagtgga tgccgacgca
     5521 gtcgtccacc aactacagaa acctggtggt cgtctgtttg aggctctagt acagcacttt
     5581 gggcaagaaa tcattcttga aaacggagaa ctcaatcgcc ctctcctagc tagtctcatc
     5641 ttttcaaatc ctgaagagca aaaatggtct aagcaaattc aaggggagat tatccgtgag
     5701 gaactggcta ctttgagaga acagttggct cagacagaag agattttctt catggatatt
     5761 cccctacttt ttgagcagga ctacagcgat tggtttgctg agacttggtt ggtctatgtg
     5821 gaccgagatg cccaagtaga acgcttaatg aaaagggacc agttgtccaa agatgaagct
     5881 gagtctcgtc tggcagccca gtggccttta gaaaaaaaga aagatttggc cagccaggtt
     5941 cttgataata atggcaatca gaaccagctt cttaatcaag tgcatatcct tcttgaggga
     6001 ggtaggcaag atgacagaga ttaactggaa ggataatctg cgtattgcct ggtttggtaa
     6061 ttttctgaca ggagccagta tttctttggt tgtacctttt atgcccatct tcgtggaaaa
     6121 tctaggtgta gggagtcagc aagtcgcttt ttatgcaggc ttagcaattt ctgtctctgc
     6181 tatttccgcg gcgctctttt ctcctatttg gggtattctt gctgacaaat acggccgaaa
     6241 acccatgatg attcgggcag gtcttgctat gactatcact atgggaggct tggcctttgt
     6301 cccaaatatc tattggttaa tctttcttcg tttactaaac ggtgtatttg caggttttgt
     6361 tcctaatgca acggcactga tagccagtca ggttccaaag gagaaatcag gctctgcctt
     6421 aggtactttg tctacaggcg tagttgcagg tactctaact ggtcccttta ttggtggctt
     6481 tatcgcagaa ttatttggca ttcgtacagt tttcttactg gttggtagtt ttctattttt
     6541 agctgctatt ttgactattt gctttatcaa ggaagatttt caaccagtag ccaaggaaaa
     6601 ggctattcca acaaaggaat tatttacctc ggttaaatat ccctatcttt tgctcaatct
     6661 ctttttaacc agttttgtca tccaattttc agctcaatcg atcggcccta ttttggctct
     6721 ttatgtacgc gacttagggc agacagagaa tcttcttttt gtctctggtt tgattgtgtc
     6781 cagtatgggc ttttccagta taatgagtgc aggagtcatg ggcaagctag gtgacaaggt
     6841 gggcaatcat cgtctcttgg ttgtcgccca gttttattca gtcatcatct atctcctctg
     6901 tgccaatgcc tctagccccc ttcaactagg actctatcgt ttcctctttg gcttgggaac
     6961 cggtgccttg attcccgggg ttaatgccct actcagcaaa atgactccca aagccggcat
     7021 ttcgagggtc tttgccttca atcaggtatt cttttatctg ggaggtgttg ttggtcccat
     7081 ggcaggttct gcagtagcag gtcaatttgg ctaccatgct gtcttttatg cgacaagcct
     7141 ttgtgttgcc tttagttgtc tctttaacct gattcaattt cgaacattat taaaagtaaa
     7201 ggaaatctag tgcgagtaaa aattaatctc aaatgctcct cttgtgacag tatcaattac
     7261 ctaaccagta aaaattcaaa aacccatcca gacaagattg aggttttaaa gtattgtccc
     7321 aaggaaagaa aagtaaccct acatcttgaa tctaagtaga ttttatggta aaataatagg
     7381 gattttaagg agtttgatat gtataaccta ttattaacca ttttattagt attatctgtt
     7441 gtgattgtga ttgcaatttt catgcaacca accaaaaacc aatccagcaa tgtatttgat
     7501 gccagttcag gtgatttgtt tgaacgcagt aaagctcgcg gttttgaagc tgtaatgcag
     7561 cgtttgacag ggattttagt ctttttctgg ctagccattg ccttagcatt gacggtatta
     7621 tcaagtagat aagaaaataa tgggcaggac taggtctttg cctcttttta tttttaaagg
     7681 atgtttgaga aggttttaca gtaaaagaaa attaaaaaat ctagaaagaa aatatgaaag
     7741 atagaataaa agaatattta caagacaagg gaaaggtgac tgttaatgat ttggctcagg
     7801 ctttgggaaa agacagttcc aaggattttc gtgagttgat taaaaccttg tccttaatgg
     7861 aaagaaagca ccagattcgc tttgaagaag atggcagtct gaccttggaa gccaagaaaa
     7921 aacatgagat taccctcaag gggatttttc atgcccataa aaatggtttt ggttttgtca
     7981 gcctagaagg ggaagaggac gacctttttg tagggaaaaa tgatgtcaac tatgctattg
     8041 atggtgatac cgtcgaggta gtgattaaga aagtcgctga ccgcaataag ggaacagcag
     8101 cagaagccaa aattattgat atcctagaac acagtttgac aacagttgtc gggcaaatcg
     8161 ttctggatca ggaaaagcct aagtatgctg gctatattcg ttcaaaaaat cagaaaatca
     8221 gtcaaccgat ttatgttaag aaaccagccc taaagttaga aggaacagaa gttctcaagg
     8281 tctttatcga taaataccca agcaagaaac atgatttctt tgtcgcgagt gttctcgatg
     8341 tggtgggaca ctcaacggat gtcggaattg atgttcttga ggttttggaa tcaatggaca
     8401 ttgtatccga gtttccagaa gctgttgtta aggaagcaga aagtgtgcct gatgctccgt
     8461 ctcaaaagga tatggaaggt cgtctggatc taagagatga aattaccttt accattgacg
     8521 gtgcggatgc caaggacttg gacgatgcag tgcatatcaa ggctctgaaa aatggcaatc
     8581 tggagcttgg ggttcacatc gcagatgttt cttattatgt gaccgagggg tctgcccttg
     8641 acaaggaagc ccttaaccgt gcgacttctg tttacgtgac agaccgagtg gtgccaatgc
     8701 ttccagaacg actatcaaat ggcatctgct ctctcaatcc ccaagttgac cgcctgaccc
     8761 agtctgctat tatggagatt gataaacatg gtcgtgtggt caactatacc attacacaaa
     8821 cagttatcaa gaccagtttt cgtatgacct atagcgatgt caatgatatc ctagctggcg
     8881 atgaagaaaa gagaaaaaaa tatcataaaa ttgtaccaag tatcgaactc atggccaagc
     8941 ttcatgaaac tttagaaaac atgcgtgtga aacgtggagc tctcaatttt gataccaatg
     9001 aagcgaagat tttagtggat aaacaaggta agcctgttga tatcgttctt cggcagcgtg
     9061 gtattgccga gcggattatt gagtctttta tgttgatggc taatgaaaca gttgccgaac
     9121 atttcagcaa gttggatttg ccttttatct atcgaattca cgaggagcct aaggctgaaa
     9181 aggttcagaa gtttattgat tatgcttcga gttttggctt gtgcatttat gggactgcca
     9241 gtgagattag tcaggaggca cttcaagaca tcatgcgtgc tgttgaggga gaaccttatg
     9301 cagatgtatt gtccatgatg cttcttcgct ctatgcagca ggctcgttat tcggagcaca
     9361 atcacggcca ctatggacta gctgctgact attatactca ctttaccagt ccaattcgtc
     9421 gttatccaga ccttcttgtt caccgtatga ttcgagatta cggctgttct aaggaaatag
     9481 cagagcattt tgaacaagtg attccagaga ttgcgaccca gtcttccaac cgtgaacgtc
     9541 gtgccataga agctgagcgt gaagtcgaag ccatgaaaaa ggctgagtat atggaagaat
     9601 acgtgggtga agagtatgat gcagttgtat caagtattgt caaattcggt ctctttgtcg
     9661 aattgccaaa cacagttgaa ggcttgattc acatcactaa tctacctgaa ttttatcatt
     9721 tcaatgagcg tgatttgact cttcgtggag aaaaatcagg tatcactttc cgagtgggtc
     9781 agcagatccg tatccgtgtt gaaagagcgg ataaaatgac tggagagatt gatttttcat
     9841 tcgtacctag tgagtttgat gtgattgaaa aaggcttgaa acagtctagt cgtagtggca
     9901 gagggcgtgg ttcaaatcgt cgttcggata agaaggaaga caagagaaaa ttaggacgct
     9961 caaatgataa gcgtaagcat tcacaaaaag acaagaagaa aaaaggaaag aaaccttttt
    10021 acaaggaagt agctaagaaa ggagccaagc atggcaaagg gcgagggaaa ggtcgtcgca
    10081 caaaataaaa aggcacgcca cgactataca atcgtagata cgctagaggc agggatggtc
    10141 ctgactggaa ctgaaatcaa gagtgtacga gctgctcgaa ttaatctcaa ggatggcttt
    10201 gctcaagtga aaaatggaga agtttggctg agcaatgttc atatcgcgcc ttacgaagag
    10261 ggcaatatct ggaaccagga accagaacgt cgtcgtaaac tcctgctcca taaaaagcaa
    10321 attcaaaaat tggaacaaga gaccaaaggg acaggaatga ccttagttcc ccttaaggtc
    10381 tatataaaag atggctacgc taagcttctt ttaggacttg ccaaagggaa gcatgactat
    10441 gacaaacggg agtctatcaa acgtcgtgag caaaatcgag atatcgcgcg tgtgatgaaa
    10501 gctgttaatc agcgataaaa agaggaattg aaaatggaaa aattagttgc ctataaacgc
    10561 atgcctttgt ggaataaaca aacaatgcct gaagctgttc agcaaaagca caatacaaaa
    10621 gttgggactt gggggaaaat tactgtcttg aagggagctc tcaagtttat tgaattgaca
    10681 gaagaagggg aagttctagc tgaacacctc tttgaagcag gggcagacaa tccaatggcc
    10741 caacctcaag cctggcaccg agtggaagct gccacagatg atgtggaatg gtacttggaa
    10801 ttttattgta aacctgagga ttattttgct aaaaaataca ataccaatcc tgttcattca
    10861 gaggtcctag aggccatgca gacagtgaaa caagggaaag ctttggattt gggttgtggt
    10921 caggggcgta attctctttt tctagcccag caagattttg atgtgacggc tgtagatcaa
    10981 aatggactgg ctcttgaaat cttgcaaagc attgtggagc aggaagattt ggacatgcct
    11041 gttggccttt acgatatcaa ttcagctagc attggacaag aatatgattt tatcgtttca
    11101 acagttgttc tcatgtttct acaagcggac cgcattccag ctattattca aaatatgcag
    11161 gagaaaacca gtgttggtgg ttacaacctt atcgtttgtg ccatggacac ggaggattat
    11221 ccttgctcgg ttaatttccc attcaccttt aaagaaggag aactggcaga ctattacaag
    11281 gattgggaat tggttaagta caatgaaaat ccaggccatt tgcatcgtcg cgatgagaat
    11341 ggcaatcgta ttcaactacg ctttgcgacc ttactagcta agaaaatcaa gtaaacacac
    11401 atgaagatta ggaattttcc tgatcttttt tcttttttac gaatgatata gaaaaggagg
    11461 gaattcatgt ttgttgcgag agatgctagg ggagaattgg taaatgtgtt agaggataaa
    11521 cttgagaagc aagcatacac ctgcccagct tgtggaggcc agctccattt gcgtcaagga
    11581 ccaagtgtac ggacgcattt tgcccataaa tccttaaaag actgtgattt tttctttgaa
    11641 aatgaaagtc cagaacacct ggccaataag gaatccctct atcactggtt gaaaaaagag
    11701 acaaaggttc aattagagta cccgctttca gaacttaaac agattgcgga tgtatttgta
    11761 aatggcaatc tagctctaga agttcagtgt agtcccttgc ctcagaaagt ccttaaagag
    11821 cgaagtgagg gatatcgtag tcagggttac caagtactgt ggttgctggg tcaaaaactg
    11881 tggctcaagg agcgtttgac tcgtctacag caaggttttc tttatttcag tcaaaacatg
    11941 ggcttttatg tttgggaatt agacaaggaa aaacaagttt taagactcaa atacctgatt
    12001 taccaggatc tccgcggtaa actccattat caaatcaagg aattttccta tggtcaaggt
    12061 agtttattgg aaatattgcg tcttccctat aagagacaaa aaatatctca ttttacagtt
    12121 tctgaggaca aggacatctg tcgctatatc cggcaacaac tttattatca aaatctcttt
    12181 tggatgaaag aacaagcaga agcctatcaa aagggagaaa atatcctgac ttatggactg
    12241 aaagaatggt atccacaaat tcgaccaata gtgggcaaat ttttccagat tgaacaagac
    12301 ttgactagct attatcagta cttttatacc tattaccaaa aaaatcctca aaatgattgg
    12361 caaaagcttt atccaccagc cttttatcag caatatttct tgaaaaatat ggtagaataa
    12421 aaaggatgga ggaatctaat ggtattacaa agaaatgaaa taaatgaaaa agatacatgg
    12481 gatctatcaa cgatctaccc aactgaccag gcttgggaag aagccttaaa agatttaaca
    12541 gaacaattgg agacagtagc ccagtatgaa ggccatctct tggatagtgc ggataaccta
    12601 ctagaaatca ctgaattttc tcttgaaatg gaacgccaga tggagaagct ttacgtttat
    12661 gctcatatga agaatgacca ggatacacgt gaagctaagt atcaagagta ctatgccaag
    12721 gccatgacac tctacagcca gttagaccaa gccttttcat tctatgatcc tgaatttatg
    12781 gagattagcg aaaagcagta tgctgacttt ttagaagctc aaccaaagct gcaggtttat
    12841 caacactatt ttgacaagct cttgcaaggc aaggatcacg ttctttcaca acgtgaagaa
    12901 gaattattgg ctggagctgg agaaatcttt ggttcagcaa gtgaaacctt cgctatcttg
    12961 gacaatgcgg atattgtgtt cccttatgtc ctagacgatg atggtaaaga agttcagcta
    13021 tctcatggga cttacacacg tttgatggag tctaaaaaac gtgaggttcg ccgtggtgcc
    13081 tatcaagctc tttatgcgac ttacgaacaa ttccaacaca cctatgccaa aaccttgcaa
    13141 accaatgtta aggtgcaaaa ttaccgtgct aaagttcgta actacaagag tgctcgtcat
    13201 gcagccctcg cagcgaattt tgttccagaa agtgtttatg acaatttggt agcagcagtt
    13261 cgcaagcatt tgccactctt acatcgctat cttgagcttc gttcaaaaat cttggggatt
    13321 tcagatctca agatgtacga tgtctacaca ccgctttcat ctgttgaata caattttacc
    13381 taccaagaag ccttgaaaaa agcagaagat gctttggcag tcttgggtga ggattacttg
    13441 agccgtgtca aacgtgcctt cagcgagcgt tggattgatg tttacgaaaa tcaaggcaag
    13501 cgttcaggtg cctactctgg tggttcttac gataccaatg cctttatgct tctcaactgg
    13561 caggacaatc tggacaatct ctttactctt gttcatgaaa caggtcacag tatgcattca
    13621 agctatactc gtgaaactca gccttatgtt tacggagatt actctatctt tttggctgag
    13681 attgcctcaa ctaccaatga aaatatcttg acggagaaat tattggaaga agtggaagac
    13741 gacgcaacac gctttgctat tctcaataac ttcctagatg gtttccgtgg aacagttttc
    13801 cgccaaactc aatttgctga gtttgaacac gccattcacc aagcagatca aaatggggag
    13861 gtcttgacaa gcgatttcct aaataaactc tacgcagact tgaaccaaga gtattatggt
    13921 ttgagtaagg aagacaatcc tgaaatccaa tacgagtggg ctcgcattcc acacttctac
    13981 tataactact atgtatatca atattcaact ggctttgcgg ccgcctcagc cttggctgaa
    14041 aaaattgtcc atggtagtca agaagaccgt gaccgctata tcgactacct caaggcaggt
    14101 aagtcggact atccacttaa tgtcatgaga aaagctggtg ttgatatgga gaaggaagac
    14161 tacctcaacg atgcctttgc agtctttgaa cgccgtttaa atgagtttga agcccttgtt
    14221 gaaaaaatag gattggcata aaatggttga atcgtatagt aagaatgcta accataacat
    14281 gcgtcgtcct gtcgtcaaag aagaaattgt agacttgatg cgtcagcgtc aaaagcaagt
    14341 cacaggttcc ttgaaagaat tggaagactt tgcccgcaag gaaaatattc ctattattcc
    14401 ccatgaaacg gttgcttatt tccgttttct tatggaaacc atgcagccta aaaatattct
    14461 ggaaattggg acggctatcg gtttttcagc tctcttgatg gctgaacatg cgccaaatgc
    14521 taagattaca actattgatc gtaatccaga aatgattggt tttgccaagg aaaattttgc
    14581 ccagtttgac agtcgcaagc aaatcactct cctagaggga gatgcggtgg atgtcttatc
    14641 tacactgaca gagtcttatg atttcgtctt tatggattct gccaagtcta aatacatcgt
    14701 ctttctgcca gaaatcctca aacatttgga agttggtggt gtggttgtct tggatgatat
    14761 ttttcaaggt ggtgatgttg ccaaggatat tatggaagtc cgtcgtggtc agcgaaccat
    14821 ttatcgaggc cttcaaaaat tatttgatgc aaccttagac aatccagaac tcaccgcaac
    14881 attagtgcct ttaggagatg gtattctcat gcttcgtaaa aatgtagcag atgttcaact
    14941 gtctgaaagc gaatgatttt cagaaaaatt taagaaaaaa tagtaaaata gatagagtaa
    15001 cacttatctc aaaggagtag acatgaagaa aaaattattg gcaggtgcca tcacactatt
    15061 atcagtagca actttagcag cttgttcgaa agggtcagaa ggggcagacc ttatcagcat
    15121 gaaaggggat gtcatcacag aacatcaatt ttatgagcaa gtgaaaagca acccttcagc
    15181 ccaacaagtc ttgttaaata tgaccatcca aaaagttttt gaaaaacaat atggctcaga
    15241 gcttgatgat aaagaggttg atgatactat tgccgaagaa aaaaaacaat atggcgaaaa
    15301 ctaccaacgt gtcttgtcac aagcaggtat gactcttgaa acacgtaaag ctcaaattcg
    15361 tacaagtaaa ttagttgagt tggcagttaa gaaggtagca gaagctgaat tgacagatga
    15421 agcctataag aaagcctttg atgagtacac tccagatgta acggctcaaa tcatccgtct
    15481 taataatgaa gataaggcca aagaagttct cgaaaaagcc aaggcagaag gtgctgattt
    15541 tgctcaatta gccaaagata attcaactga tgaaaaaaca aaagaaaatg gtggagaaat
    15601 tacctttgat tctgcttcaa cagaagtacc tgagcaagtc aaaaaagccg ctttcgcttt
    15661 agatgtggat ggtgtttctg atgtgattac agcaactggc acacaagcct acagtagcca
    15721 atattacatt gtaaaactca ctaagaaaac agaaaaatca tctaatattg atgactacaa
    15781 agaaaaatta aaaactgtta tcttgactca aaaacaaaat gattcaacat ttgttcaaag
    15841 cattatcgga aaagaattgc aagcagccaa tatcaaggtt aaggaccaag ccttccaaaa
    15901 tatctttacc caatatatcg gtggtggaga ttcaagctca agcagtagta catcaaacga
    15961 atagtccaaa tcaatgagtc agggaaaaaa ctcgacttca ggaaaaaatg aagcaaacat
    16021 tcccacaata aaacgcatag tacaaggttt gtactgcccc ccaaaaaagt tagacaatta
    16081 atttatccga aggatttagt tctgtattgc acagagctaa gtccttttag ttttatctta
    16141 attctcttat tgttgtaata atcaatatag tctataatgg cttgttccaa ttgattaagt
    16201 gatttaaatg tttgctcata gccataaaac atttcggatt ttaaaatgcc aaagaaagat
    16261 tccatcctac cgttgtcttg gctgtttcct ttgcgtgaca tagatgcttg aattccctta
    16321 ctctctagga agcgatgata agaatcgtgt tggtattgcc agccttggtc actatggaga
    16381 atcgtattct cgtagtgctt ctctttgaat gctgttccaa ca
//
LOCUS       DAVAGB010000045        16035 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVAGB010000045 DAVAGB010000000
VERSION     DAVAGB010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16035
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.045"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     regulatory      75..163
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            378..1046
                     /locus_tag="VQO19_001665"
     CDS             378..1046
                     /locus_tag="VQO19_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HET1349896.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            1334..2116
                     /gene="thiM"
                     /locus_tag="VQO19_001666"
     CDS             1334..2116
                     /gene="thiM"
                     /locus_tag="VQO19_001666"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET1349897.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEIAEKHPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            2118..2747
                     /locus_tag="VQO19_001667"
     CDS             2118..2747
                     /locus_tag="VQO19_001667"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET1349898.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFGTQSKDDAGGTIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      2956..3044
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            3306..3866
                     /locus_tag="VQO19_001668"
     CDS             3306..3866
                     /locus_tag="VQO19_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET1349899.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            3867..5252
                     /locus_tag="VQO19_001669"
     CDS             3867..5252
                     /locus_tag="VQO19_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1349900.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSNGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILLQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDYMVELRDGKLREVFQIPS
                     YEMTQVASKEVAASPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            5254..5904
                     /locus_tag="VQO19_001670"
     CDS             5254..5904
                     /locus_tag="VQO19_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HET1349901.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            5915..6607
                     /gene="tenA"
                     /locus_tag="VQO19_001671"
     CDS             5915..6607
                     /gene="tenA"
                     /locus_tag="VQO19_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HET1349902.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            6612..7136
                     /gene="thiW"
                     /locus_tag="VQO19_001672"
     CDS             6612..7136
                     /gene="thiW"
                     /locus_tag="VQO19_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HET1349903.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            7136..7939
                     /locus_tag="VQO19_001673"
     CDS             7136..7939
                     /locus_tag="VQO19_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET1349904.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     SREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSKNQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            7932..8555
                     /locus_tag="VQO19_001674"
     CDS             7932..8555
                     /locus_tag="VQO19_001674"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET1349905.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(8764..9555)
                     /gene="thiD"
                     /locus_tag="VQO19_001675"
     CDS             complement(8764..9555)
                     /gene="thiD"
                     /locus_tag="VQO19_001675"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET1349906.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEGMQRA
                     GRLILKEFGPESVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(9639..9737)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            9921..10316
                     /locus_tag="VQO19_001676"
     CDS             9921..10316
                     /locus_tag="VQO19_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HET1349907.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLL
                     ARLVEKECLTRKKEGKFFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            10327..10698
                     /locus_tag="VQO19_001677"
     CDS             10327..10698
                     /locus_tag="VQO19_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HET1349908.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            10708..12951
                     /locus_tag="VQO19_001678"
     CDS             10708..12951
                     /locus_tag="VQO19_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET1349909.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            13158..14933
                     /gene="spxB"
                     /locus_tag="VQO19_001679"
     CDS             13158..14933
                     /gene="spxB"
                     /locus_tag="VQO19_001679"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HET1349910.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            15044..15391
                     /locus_tag="VQO19_001680"
     CDS             15044..15391
                     /locus_tag="VQO19_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET1349911.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEIEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(15508..16035)
                     /locus_tag="VQO19_001681"
                     /pseudo
     CDS             complement(15508..16035)
                     /locus_tag="VQO19_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         4750 a         2947 c         3505 g         4833 t
ORIGIN      
        1 tataaagata tttttcggtc aaatatcttg ctagggcttt cattttttgc tatactggtt
       61 cagtaattaa ataatagaga catttggggt gctttaagct gagatgatac ccattgaacc
      121 tgatacagtt aagactggcg aagggaaatg tgaaacgttt tttcgtatgg cgaaatgaac
      181 gatctaatct tgtaagtcaa ctctaattct tgattgtaat tggagttttt tgtttatata
      241 aactggatag gcttgtttag ttagctctct gcaaatactc tcgatgtgtt ttaaaaggat
      301 caagtggaat tacgattttg cttgatattt cttggtgttt tattaattac taacaagtaa
      361 agagaggaga agtaaatatg gaaacacaag actatgcatt tcagccaggt ttgactgttg
      421 gagaattatt aaaaagcagt cagaaggatt ggcaggctgc aatcaatcat cgttttgtta
      481 aggaactttt tgcggggaca attgagaata aggtcttaaa ggactatctg attcaagatt
      541 atcacttctt tgatgccttc ttatccatgc tgggtgcctg cgtagctcac gcagataaac
      601 ttgaatccaa gcttcgtttt gccaagcaac taggctttct tgaagcagat gaagatggtt
      661 atttccaaaa ggcttttaaa gagttaaaag tagcagagaa tgactatcta gaagtgactt
      721 tgcaccctgt aacaaaagcc tttcaggatc taatgtattc ggcggtggct tcatcagact
      781 atgcccatct tttggtcatg ctggtcattg cagaaggtct ctatttagac tggggttcta
      841 aagatttggc tttacctgaa gtctatattc attcggaatg gatcaatctc cacagaggtc
      901 ctttctttgc agagtgggtt caatttctgg ttgacgaact caatcgtgtc ggtaaaaatc
      961 gagaagattt gacagaactt cagcaacgct ggaatcaagc agtcgcttta gaattagctt
     1021 tttttgatat tggttacgat gtctagagaa ggctcatgat atttacaaat ttgatgaggt
     1081 aagactcttc gaaaatctct tcaaaccacg tcagttctat ccacaacctc aaaacagtgt
     1141 tttgagctga cttcgtcagt cttatctaca ggctcaaagc agtgttttga gcaacctgcg
     1201 gttagcctcc tagtttgctc tttgattttc attgagtata aatcattcaa tgtaaatgaa
     1261 aaaaattctt aacgaaagat agaaataaat cgaaatcagt agatcgtata aagtgaaaag
     1321 gaaggatttc aatatgacaa gtttaaaatt attaaaagaa aaagcaccat tggtcatttg
     1381 tataaccaat gatgtagtaa aaaatttcac agcaaatgga ttagtagcac tgggcgcctc
     1441 accagccatg agtgagtttc cagcagattt agaggatttg ttaaagtatg ctggtggttt
     1501 attaataaac ataggaacat tgacagatga aaattggaaa ttataccaag ctgctctgaa
     1561 aattgcggag aaatataatg tcccagcagt tttagatcct gtagcctgtg gagcaggaga
     1621 atatagaaaa aaagtagcag atgatctaat caacaattat aaactagcag cgattagagg
     1681 aaatgctggc gagattgcct ctttagtagg aatagatgtg gcatctaaag gagtagatag
     1741 tgcgggcgta gataatattg acgaaattgc tctagcagca aatgagaagt tcaatattcc
     1801 aatagtagta acaggtgaag tggatgccat tgctgttaat ggagaagtgg taacgattca
     1861 taatggtagt gctatgatgc cgaaagtcat tgggacagga tgcttattag gagctgtagt
     1921 agcaagcttt atcggactag aaaaaggtca agaattgaaa tcattagaaa cagcaatgtt
     1981 ggtttacaat atcgctggag aaatagcaga aaaacatcca aatggacatc ttcctgggac
     2041 atttaaagtt gaatttataa atgccttata cgagattaca gatgaagatg taaaggaatt
     2101 caaaagagtg aagtaagatg tttcataaag aattactaaa actatatttt atttgtggaa
     2161 cgactacttg ccaaggaaaa aatctatata cagtcgttga ggaagcctta aaaggtggta
     2221 taaccttatt tcaatttcga gaaaaaggtg agggtgcttt agaaggctta gaaaaacttg
     2281 agctagctat ccaaattaaa gaactttgta aaaaatacaa tgttccattt atcgttaatg
     2341 acgatataga tttagcaatg gaaattgacg ccgatggcgt acatgtaggt caagatgata
     2401 ttggtgttga tgaaattaga aaattgatgc cagataaaat aattggtctt tctataagaa
     2461 acgaagaaga atttcaacaa tcaaaagttg aatatgtaga ttatgtaggt gttgggcctg
     2521 tatttggtac ccagtcaaag gatgatgctg gtggtactat aggttatgaa ggtcttgaat
     2581 tgatgagaaa actattgcca caaatgcctt tagttgcaat tggtgggata cagacgaaac
     2641 atattaaaga cattataaag accaatatgg atggcgtttc aatcatttcg gcaatatcgt
     2701 atgcaaaaaa tatagaaaaa actgttcggg aaatgagtga acaatagata tctatccttg
     2761 gattctaagt aagtaggatt ttcctttttt aaaaagctat gtccagattc agcttgaatg
     2821 gctaattcat caaacaggtc atttgttttt tgcaaaagaa aaatctgctg tctttgtgag
     2881 tgcaaggctg tatttccagt tcaatttctt gaactagtat aaaatgtgtg ttataataat
     2941 cacataatta aataataaag acatttgggg tgctttaggc tgagatgata cccattgaac
     3001 ctgatacagt taagactggc gaagggaaat gtgaaatgtt tttttcgtat gtcgaaaaga
     3061 actgtctaat cttgtaagct gaactctaat tcgtatctgt aattagagtt ttttctttta
     3121 cgaaactgga tgaagatgat atagtagatt gaaataagat gcgaacaaat caattataaa
     3181 attcaaatta atttctagaa atattttagt gttcttgtgt actgttctaa attcagtctg
     3241 ctatacaaag tatttaggtc tgtcttcttg agtgccccac ttttctttaa aaaaaggagt
     3301 tttttatgtt gaaaaaatgg cagttaaaag atgttatctt gcttgctttc ttgtctatct
     3361 tttttggtgg ggttttcgtt ggttcaggat atgtgtataa tattctcagt ctactcttaa
     3421 cacctcttgg tttgcaggcc tttgccaatg aaatcctctt cggtctctgg tgtatggctg
     3481 cgcccattgc tgccatcttt gttccgagag tcggaagtgc aacgattgga gaagtgctag
     3541 ctgcgcttgc tgaagtcctt tatggtagcc aatttggtct aggagctctt ttgtctggct
     3601 tggttcaagg tttgggaagt gaatttggtt ttatcgtaac taagaatcgc tatgaaagtt
     3661 ggctctctct aactgctaat agtattggga ttacgcttgt tagctttgtc tatgaataca
     3721 ttaagttagg ctactacgcc ttttcccttc cgtttgtcct ttccttgctt gtggtacgtt
     3781 ttatttctgt ttatttcttc tgtaccatct tggttcgtgc cattgtcaaa ctctatcatc
     3841 agtttgcaac tggaggaaaa gcatagatgg gtctggaact acgagcgatt cagtccccaa
     3901 tcttctctga gccgtttgat tttacttttc atgcgcaagc ctttaccttg ttagttggga
     3961 gcaatggttc aggaaaatcc agcctctttc aaatgattgc ccaagtcagt tctcttccct
     4021 atagtggtca agtcctgata gatgggagcg aggtcagtca gctttctatc atcgcacgtg
     4081 tccagaaggt tggcattctc ttgcaaaatc ccaatcatca atttaccatg gagaacttgt
     4141 ttgaggagct gattttcacc ttggagaata tcggctatca ccttcaggaa attgattcta
     4201 aaatagcaga ggttgtccag caatgtcgtt gcgaggcaat cttacaccgt cccattcatc
     4261 acctatcagg tggggaaaag caaaaagcag cgctggctgt cctctttgcc atgaatccta
     4321 gggtctatct cttggatgag cccttcgctt ccattgaccg caagagtaga atcgagatat
     4381 tggagattct aaaagagttg gctcttgatg ggaagacagt cattttgtgc gaccatgatt
     4441 tatctgacta taaagcctat atcgactata tggttgagct aagagacgga aaactaaggg
     4501 aagtgtttca aatcccttcc tatgagatga cacaggttgc ttcaaaggaa gttgctgcta
     4561 gcccggaatt attccatatg aaccgtgtga ctggtgagct tggtaatcgc cccctctttt
     4621 caattgctga tttcacattc tatcaaggga tttcctgtat cctgggtgac aatggtgtcg
     4681 ggaaatcaac cctctttcgg tctattcttc aatttcaaaa gtataagggg cgcattgcat
     4741 ggaaggggac agtcctgaaa aagaaaaaga gtttgtaccg tgatctgacg ggtgttgttc
     4801 aggaagctga gaagcagttt atccgagtca gtctgcgaga ggagcttcaa ttagatggac
     4861 ctgattctga aagaaatcag cggatttttc aagctttacg atattttgat ttggagcagg
     4921 cagtcgataa gagtccctat caattaagtg gtggtcagca aaaaattctt cagctcctga
     4981 ccatcttgac cagtaaggct tccgtgatct tgctagatga accttttgca ggtttggatg
     5041 atagagcctg ccattatttt tgcaagtgga ttgtggagga gaggaaccaa ggaagaagtt
     5101 ttctgctcat tagtcatcgt ttagaccctt tgatttctgt ggttgattat tggattgaga
     5161 tgactagtca gggtcttcgg catgtgaaag aagtgaccat taccaaacca cttacatctc
     5221 agagtagcaa tacccaaggg gaggtgagat agtatggtca aagtagcaac ccagacaccg
     5281 attatcagtc tcttcttgct gattttatcc ttggaaacat ctttcattcc ttcgattgct
     5341 ctgaatcttt cggtagtcgc attttgtatt ctctttatgc tctattaccg tcgatttaaa
     5401 atgttagctt ggatgatcat acttgccatt ttaccatctt ttgccaacta ctgggcagtt
     5461 cagttacacg gagatgcttc acaggcagtc atgcttggaa cgagggcttt tgtgacagtt
     5521 tgtatcggcc ttgtctttgt ttcctctatt tcactaaaag agcttctctt gtacttggct
     5581 caaaaggggc tatcacgctc ttggtcctat gccttgattg tggtattcaa ttcctttcct
     5641 ctcattcagc aagaaatcaa gtccctcaaa gaagcttgcc tattacgtgg tcaagaacta
     5701 catttttggt cgcccttgat ttacagtaag gttctgatga cagtctttag gtggcgccat
     5761 ctttacctga gagctctatc tgctcacgga tatgacgaac atgcacagtt gaagaatagc
     5821 tatcggactt tttatattcc taaaaaaaca aaattaatct acctgctttt ctttttattg
     5881 cttcaaacca gtctattttt ataaaggagt tattatggaa tttacagata ttgcgatgga
     5941 attatccaag aaagcttggc aggcttcctt tcatcatccc tttattttac aattacaaga
     6001 ggggaattta gaacctgcca ttttccgcta ttacctgatt caggatgcct actatctgaa
     6061 ggctttctca gaaatctatc atctgttggc tgataagact tcaaaccaag agatgaaaag
     6121 actcttgaaa caaaatgctc agggtttagt ggagggtgag ttatttattc gccaacaatt
     6181 tttcaaggaa ttggaaatca acgaccagga aatggagcaa catccaatcg ctccaacctg
     6241 ttatcattac atttctcata tttataggca atttgcagaa ccgaacttag ccatagcttt
     6301 tgcaagcttg cttccttgtc cttggttata ccatgatata ggcaaatcac ttaatcttaa
     6361 accatcacca aatcctctct atcaacaatg gattgaaact tatattacgg atgagttaga
     6421 gcaacagatc agagaggagg gagcactggt caatcagctc tatcgagaaa gtgatgagac
     6481 agataagcaa aaaatgctag atgccttcca catcagtgtt catatggaag ccaagttttg
     6541 ggagatggct taccaacacc agacatggaa gagcgattta cagtctttag aaaaaggaga
     6601 agaatagaaa catgagaaag caccaactac aagttcacaa attgaccatt ttatctatga
     6661 tgattgccct tgatgtagtc cttacaccta tctttcggat tgagggaatg gcaccgatgt
     6721 ccagtgtagt caatattcta gcgggaatca tgatgggacc tgtttatgcc ttggctatgg
     6781 ctacagtgac agcctttatc cgtatgacga ctcaagggat tccgccttta gctctcacag
     6841 gagcgacttt tggagccctt ctagcaggtc tcttttataa gtacggtcga aaattttact
     6901 tttctgcctt gggagaaatt gtgggaacag gtattattgg ttctattgtt tcctatcctg
     6961 ttatggtact ctttacagga tcagctgcta agcttagctg gtttatctac acgcctcgat
     7021 ttttcggagc aaccttgatt ggtacagcga tttcctttat tgcctttcga tttttaatca
     7081 agcaggaatt ctttaaaaaa gtgcagggat atttctttag tgaaaggata gactgatgca
     7141 ggaatttaca aatccctttc ctataggctc tagttccctc attcactgta tgaccaatga
     7201 gatttcttgt gagatgctgg caaatgggat tttggctctg ggatgcaaac ctgtcatggc
     7261 agatgattcc cgtgaagttc ttgattttac taagcaaagt caggctctct tcatcaattt
     7321 aggtcatttg tcagctgaga aggagaaagc aatccgcatg gcagcttcgt atgcaaacca
     7381 atcttctctc ccgatggtag tagatgcggt tggcgtaacg acttcatcca ttcgtaagag
     7441 cttagttaaa gaccttttag actatagacc tacggtcctt aaaggaaaca tgtcagaaat
     7501 tcgaagtctt gttggattaa agcaccacgg cgttggggtc gatgcgagtg ctaaagatca
     7561 agaaacggag gatttgcttc aagtcttgaa agactggtgt cagacctatc ctggtatgtc
     7621 attcttagtt actggcccca aggacctcat cgtttcgaaa aatcaggtcg ctgtactgga
     7681 gaatggctgt actgaattag actggataac agggacagga gatttggttg gagccttaac
     7741 agccgttttt ctcagccaag gaaagactgg ttttgaagct tcttgcttag cagtctctta
     7801 tctcaatatc gctgctgaga aaatagttgt tcaaggaatg ggattggaag aatttcgtta
     7861 ccaagtactc aatcagcttt cgctcctaag aagagatgaa aattggctag ataccatcaa
     7921 aggagaggtt tatgaataga gaagcactta gactatatct ggtaaccaat cgctatcaag
     7981 attccgtgga aagctttctt gcaaaagttg agacggcctg ccgttcaggg gttaccatag
     8041 tccaattgcg agaaaaaaat ctcacaacca atcaatatta tcaactggca aaacaagtca
     8101 aggaaataac agatgcttat caggtaccct tgataatcga tgatcggttg gatgtttgtc
     8161 ttgcggttga tgctgctggt ctgcatattg gagatgacga actcccagtt tcggttgccc
     8221 gacaagtctt gggtcctgaa aaaatcctcg gtgtcaccgc taaaacggtt aaaagagctc
     8281 tggaagcgga gaaatcaggt gcagattact tggggacagg agccattttt ccgacaacca
     8341 ccaaggaaaa tgcacccatc accctgattt caaccttgaa aacaatttgc caaacggttg
     8401 ccattccaat agttgctatt ggcggcttga cttcggagaa tattgatcag cttatgggca
     8461 ctggcatagc tgttgtacgt gatttgatgc aagcagaaga tattgaggca aaaacgcaag
     8521 cctttttaac aaagttgcat gacattcttt cctaattaat actcaatgaa aatcaaagag
     8581 taaactagaa agctagtcgc aggttgctca aagtactgcc ttgaggtttt agataagact
     8641 gacgaagtca gctcaaaaca gtgttttgaa gttgcagatg gaagctgacg tagtttgaag
     8701 agattttcga agagtataaa aactctctaa ttcccttaaa gtgggaacta gagagttttt
     8761 ttcttaatct ttaaaagttg tatggttgac tggaccagaa ccatgaccga gttgaggggc
     8821 atcttgaata gcttttgtga taaaggcctt ggccttatca actgcctggt aaagactctt
     8881 gcccttggct agttcagcag taatcactgc agcaaaggta catccagtac catgggtgtg
     8941 acaggtttga attcgtgggc tttcccagac aaattgttca ttcttggtaa agaggaaatc
     9001 tttagcacca cctttgagat gtccgccttt gataaccaca gactcaggac caaattcttt
     9061 taaaatcagg cgaccagcac gctgcatgcc ttcggggtca tggattgaaa aaccaacaat
     9121 ctcttctgct tcaggaagat ttggcgtaat aatagttgct agaggtagta agtttgtttt
     9181 gagatagtct ctagcacttg agtcaatcaa ggcatctcca cttgtagcaa ccataacagg
     9241 atcaaggaca tagggacaat ccagtttttt aagatagggt tggatgattt ccatgatttc
     9301 agtagtagcc aacattccag tttttacagc ctgaggtgga atatcagaaa agacactctc
     9361 caattgggct ttcaacattt gaggagaaac atgctcgatt agctgaacac ctctggtatt
     9421 ttgagcgaca agactggtta caacagccat tccatagaca tctctcgctt ggaatgactt
     9481 taaatctgcc ataatgccag caccaccact agggtcagtc cctgcaatgg tcaaagcaac
     9541 gggtaaataa gtcatctaaa acctcccaac caactgaagt ttgtattctt aagaacaagc
     9601 tagtctgttt tagaaaggca atagaagact gctagtcccc attatcattt ccacttccat
     9661 cagctagtat tacctagatt gagtcagagg gatctaacag tcgttaatct cagctttacg
     9721 cacccctagt ggttgttttc ttttttcttt agtatagcat atttttattg tttatatagt
     9781 aatatttgac tgcaaatcgt ttttcaaatg attaaaattc tatttttcga agaaaatatt
     9841 atttctataa ttgacaaatg tagattttaa gagtatactg atgagtgtaa ttgacaaatg
     9901 tagattttgg aggtatggta atgcagattt cagatgcaga atggcaggtc atgaagatta
     9961 tttggatgca gggggagcag accagtacag atttgattag ggttttggca gagcggttcg
    10021 actggtccaa gtcaaccatt caaactcttt tggctcgttt ggttgagaaa gagtgtctga
    10081 ctcggaaaaa agaaggcaag ttctttgttt attcagccct tttaactcta gaccaaagtc
    10141 gggatttact tgtccaagat atcaaagaca aggtttgttc ccgtaggatt aggaatttgt
    10201 tggctgactt gattgtagaa tgtgaattta ctcagactga cttggaagac ttggaagctg
    10261 tgatttcaga gaagaaatca agtgctgtaa cagaagtaag atgtaattgt atgtaaagga
    10321 gacgtcatgt taaatagtat tgtaaccatt atttgtattg cccttatcgc gtttatcttg
    10381 ttttggtttt tcaaaaagcc tgaaaaatct ggacaaaaag cccagcaaaa aaacggatac
    10441 caagagattc gagtggaagt catgggaggc tatactcctg agttgattgt cctcaagaaa
    10501 tcagtgccag cccgcattgt ctttgaccgc aaggatcctt caccatgtct ggatcaaatt
    10561 gtttttccag attttggtgt acatgcgaac ctgccaatgg gggaagagta tgtagtggaa
    10621 atcacgcctg aacaggctgg agagtttggc tttgcttgtg gtatgaacat gatgcacggc
    10681 aagatgattg tagagtaggt ggagactatg acagaaattg tgaaagcaag cttagaaaat
    10741 ggcattcaaa aaatccgtat ccgagctgaa aaaggctatc atccagccca tatccagctt
    10801 caaaagggaa ttccagctga gattaccttt catcgtgcta ctccttcaaa ctgttataag
    10861 gaaattctgt ttgaagaaga aggtatcttg gaaccaatcg gcgtagatga ggagaaagtc
    10921 attcgtttta cacctcaaga attagggcga catgaatttt cttgtggcat gaagatgcaa
    10981 aagggaagct atatagtcgt tgagaagact cgaaaatctc tatctctcct gcaacgtttt
    11041 tggattacta gtatctttac tgtgcctctt gtgattctca tgattgggat gttgacaggt
    11101 agcattagtc atcaagtcat gcattgggga acctttctag caacaacgcc tattatgtta
    11161 gttgcaggta agccatatat ccagagtgct tgggccagtt ttaaaaagca caatgccaac
    11221 atggatacct tggttgcgct gggaactcta gtggcttatt tctatagcct agttgctctc
    11281 tttgctggtc tccctgttta cttcgaaagt gctggattta tcctcttttt cgttcttttg
    11341 ggagcagttt ttgaggaaaa aatgagaaaa aatacgtccc aagctgtgga gaaattactg
    11401 gacttgcaag ctaaaaccgc agaagtcttg agtgatgata gttatgtcca agttcctttg
    11461 gaacaagtca aggtaggcga cctgattcga gtgcgtcccg gtgaaaagat tgctgttgat
    11521 ggtgtcgtag tagaaggtgt ctctagtatt gacgaatcca tggtgacagg tgagagtctg
    11581 cctgtggaca agacagttgg agatactgtc attggctcaa ccatcaatca tagtggaacg
    11641 cttgtcttta gagcagaaaa agttggctca gagactgttt tggctcagat tgtggatttt
    11701 gtgaagaaag ctcagacaag tcgtgcgccg attcaggact tgacggataa gatttcaggg
    11761 atttttgtcc cagtagttgt cattttagga atcatgacct tttgggtttg gttcgtcttg
    11821 ctcagggata gtgtggtcgt gcttggagct agctttgtgt cctctcttct ctacggagtg
    11881 gcggttttga ttatcgcctg tccttgtgcc ttgggacttg caacaccgac agcccttatg
    11941 gtggggacag gacgtagtgc caagatgggg gttctcctca aaaatggaac tgtcttacag
    12001 gaaatccaga aagttcaaac tcttgtcttt gataagaccg ggactttgac ggaagggaaa
    12061 cctgtggtaa cagatatcat cggcgacgaa gtagaagtgt ttggattggc agcctccttg
    12121 gaagatgctt ctcaacaccc actggctgag gctatcgtta agcgagcgag tgaagctgga
    12181 cttgagtttc aaactgttga aaattttcag gccttgcacg ggaaaggtgt ttcagggcga
    12241 atcaatggaa aacaagtttt acttggaaat gctaaaatgc tggatggcat ggatatttct
    12301 aatacttatc aagataaact agaagaacta gaaaaagaag ctaagacagt tgtgttttta
    12361 gctgttgaca atgaaatcaa aggcttgctt gctttgcaag atattcctaa ggaaaatgct
    12421 aagctagcca tcagtcagct aaaaaaacgt ggtctccgaa cagtcatgct gacaggagac
    12481 aatgctggtg tggcgcgtgc tattgcagat caaatcggaa ttgaagaggt cattgcaggc
    12541 gtcttgccag aagaaaaagc ccatgaaatc cataaactgc aacagtcagg gaaagtagcc
    12601 tttgttgggg acggtatcaa tgacgctcct gcccttagtg tagcagatgt ggggattgct
    12661 atgggagctg gaacagatat cgccatcgag tcagcagatt tggtgttgac aaccaataat
    12721 cttttaggag tggttcgtgc ctttgatatg agtaagaaaa cctttcatcg aattctactc
    12781 aatcttttct gggcttttat ctacaatgtt gtcggaattc cgattgcagc aggagtcttt
    12841 tcaggtgttg gactggctct caacccagaa ttggcaggtc tagccatggc ctttagttct
    12901 gtatctgttc tgaccagttc ccttctgtta aattttagta aaatagacta aaagtaatga
    12961 ctagatttct ttgttataaa acagaaatga cagaacttta aaaactgtat tagaatagag
    13021 aatagagagt tttgagcaga tttttagaaa agtcagcata aatatgatac agtggaatag
    13081 taaaaatttg gagaacgttt ccaattctat gtaatcgtat tctccaaatc taaaaaaatt
    13141 gaaggagagt tatcattatg actcaaggga aaattactgc atctgcagca atgcttaacg
    13201 tattgaaaac atggggcgta gatacaatct acggtatccc atcaggaaca ctcagctcat
    13261 tgatggacgc tttggctgaa gacaaagata tccgcttctt acaagttcgc cacgaagaga
    13321 caggtgctct tgcagcggtt atgcaagcta aattcggcgg ctcaatcggg gttgcagttg
    13381 gttcaggtgg tccaggtgcg actcacttga ttaacggtgt ttacgatgca gctatggata
    13441 acactccatt cctagcgatc cttggatcac gtccagttaa cgaattgaac atggatgctt
    13501 tccaagagct taaccaaaac ccaatgtaca acggtatcgc tgtttacaac aaacgtgtag
    13561 cttacgctga gcaattgcca aaagtaattg acgaagcctg ccgtgctgca gtttctaaaa
    13621 aaggtccagc tgttgttgaa attccagtaa acttcggttt ccaagaaatc gacgaaaact
    13681 catactacgg ttcaggttca tacgaacgct cattcatcgc tcctgctttg aacgaagttg
    13741 aaatcgacaa agctgttgaa atcttgaaca atgctgaacg cccagttatc tatgctggat
    13801 ttggtggtgt taaagctggt gaagtgatta ctgaattgtc acgtaaaatc aaagcaccaa
    13861 tcatcacaac tggtaaaaac tttgaagctt tcgaatggaa ctatgaaggt ttgacaggtt
    13921 ctgcttaccg tgttggttgg aaaccagcca acgaagtggt ctttgaagca gacacagttc
    13981 ttttccttgg ttcaaacttc ccatttgctg aagtttacga agcattcaag aacactgaaa
    14041 aattcatcca agtcgatatc gacccttaca aacttggtaa acgtcatgcc cttgacgctt
    14101 caatccttgg tgatgctggt caagcagcta aagctatcct tgacaaagta aacccagttg
    14161 aatcaactcc atggtggcgt gcaaacgtta agaacaacca aaactggcgt gattacatga
    14221 acaaactcga aggtaaaact gagggtgaat tgcaattgta tcaagtttac aatgcaatca
    14281 acaaacatgc tgatcaagac gctatctact caatcgacgt aggtaacact actcaaacat
    14341 ctactcgtca ccttcacatg acacctaaga acatgtggcg tacatctcca ctctttgcga
    14401 caatgggtat tgcccttcct ggtggtatcg ctgctaagaa agacaatcca gatcgccaag
    14461 tatggaacat catgggtgac ggagcattca acatgtgcta cccagacgtt atcacaaacg
    14521 ttcaatacga ccttccagtt atcaaccttg tcttctcaaa tgctgagtac ggcttcatca
    14581 agaacaaata cgaagataca aacaaacact tgtttggtgt agatttcaca aacgctgact
    14641 acgctaaaat tgcggaagct caaggagctg ttggattcac agttgaccgt atcgaagaca
    14701 tcgatgcagt tgttgcagaa gctgttaaat tgaacaaaga aggtaaaact gttgtcatcg
    14761 atgctcgcat cactcaacac cgtccacttc cagtagaagt acttgaattg gatccaaaac
    14821 ttcactcaga agaagctatc aaagccttca aggaaaaata cgaagcagaa gaactcgtac
    14881 cattccgtct cttcttggaa gaagaaggat tgcaatcacg cgcaattaaa taattcctct
    14941 cgccgaaaat caaatatgaa acttgtagac tttattcttt gattttcata gagcagaact
    15001 ttaaaagatc ggagcaatcc ggtcttttta tggaggagag taaatgaatt taaatcaatt
    15061 agatattatc gtttcaaatg ttccccaagt ctgtgctgac ttggagcata tcttggataa
    15121 aaaggcagat tatgctgatg atggttttgc tcagtttacg attggtagtc actgccttat
    15181 gttgtcacaa aatcatttgg ttcctttgga aaactttcag tcaggaatca ttattcatat
    15241 cgagattgag gatgtagacc agaactacaa acggttgaac gagcttggta taaaggtttt
    15301 acacggacca actgtaaccg attggggaac agagtcctta ttagttcaag gacctgctgg
    15361 tctagtgctt gatttttatc gtatgaaata ggtcgcgtag tcatttgacg ttaaccttag
    15421 ctatttttaa aatagaaatt gagaatatga actattgaaa gatcggagca atccggtctt
    15481 tttatataaa gaaattgcat ataatactca tctgctttca aaaagcattc tagtccatct
    15541 ccgattaacg atggacttta tcacctcctt ctccaatcct tgtatgacat cttggagttg
    15601 attcatgaca tcttccaaag ttcgaaaggc tttattctta aatccacgtt tacgaatctc
    15661 tttccacact tgttcaatgg gttcatctct ggtgtgtatg gaggaataaa tgcaaaacca
    15721 atattagtcg gaatctttaa ggtacttgat ttatgccata tagcattgtc tataacgagt
    15781 aaaaaataat catatggata agcttgtgaa agctcttcta aaaaggcgtt catccactca
    15841 gtattacatc taccagctat taagaaaaat gattcgcctg tatgggcatc aacagctcca
    15901 taacaatagc gaaattctcg tatatagtga ctatggacat gtggacctac tcctattgga
    15961 gaccaacaag atcccagttt actgattcta ccgaaaccag cttcatcttg gtacatcaag
    16021 cgaaccttat gaaaa
//
LOCUS       DAVAGB010000046        15684 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVAGB010000046 DAVAGB010000000
VERSION     DAVAGB010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15684
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.046"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(1..245)
                     /locus_tag="VQO19_001682"
                     /pseudo
     CDS             complement(1..245)
                     /locus_tag="VQO19_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            370..828
                     /locus_tag="VQO19_001683"
     CDS             370..828
                     /locus_tag="VQO19_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HET1349912.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            841..1449
                     /locus_tag="VQO19_001684"
     CDS             841..1449
                     /locus_tag="VQO19_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349913.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            1520..1852
                     /locus_tag="VQO19_001685"
     CDS             1520..1852
                     /locus_tag="VQO19_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349914.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            1863..3278
                     /gene="ply"
                     /locus_tag="VQO19_001686"
     CDS             1863..3278
                     /gene="ply"
                     /locus_tag="VQO19_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HET1349915.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            4159..4875
                     /locus_tag="VQO19_001687"
     CDS             4159..4875
                     /locus_tag="VQO19_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET1349916.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEALETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            4999..5469
                     /locus_tag="VQO19_001688"
     CDS             4999..5469
                     /locus_tag="VQO19_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET1349917.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGRQGQVVHFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQIQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQANIKGIGGENKEISQKN"
     gene            5486..6307
                     /locus_tag="VQO19_001689"
     CDS             5486..6307
                     /locus_tag="VQO19_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1349918.1"
                     /translation="MILLAILFTCFSVYLELEVPTYISKITDLLGSQGTNLDELWQPA
                     SMMMGMPFLAFLSVVAVGFFASRVAASYTSRLRSDIFNRVLDYSQTEIKKFSIPSLLM
                     RTTNDITQVQMLITMGLQVVTCGPIMAIWAIGKILGHSEYWLWAVLVAVIVNVLMTTV
                     LMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNL
                     FVNRLMAILNPIMMGISSGLSVAIYWIGAYVINDAAPIARLPLFSDMIVFMSYAM"
     gene            6314..7345
                     /locus_tag="VQO19_001690"
     CDS             6314..7345
                     /locus_tag="VQO19_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET1349919.1"
                     /translation="MDFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQNPVQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSTGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATAHAGQKVAIVGPTGTGKTTIVNLLMKFYEIDKGSIHI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNS
                     QFTEDEAEE"
     gene            7411..7773
                     /locus_tag="VQO19_001691"
     CDS             7411..7773
                     /locus_tag="VQO19_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HET1349920.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            7770..8273
                     /locus_tag="VQO19_001692"
     CDS             7770..8273
                     /locus_tag="VQO19_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET1349921.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSAGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            8387..8833
                     /locus_tag="VQO19_001693"
     CDS             8387..8833
                     /locus_tag="VQO19_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET1349922.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            8839..9513
                     /locus_tag="VQO19_001694"
     CDS             8839..9513
                     /locus_tag="VQO19_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349923.1"
                     /translation="MKKKAFGIVLLVLAALILVQGNFGIPSLGGHIWPLIGIAFFAYQ
                     SVGALLRRHLTSASFTALVSLMIANHFYGILPIPNQTLIWAGVLIVLGVNMLTHSNRT
                     WNGKKWWYDGEKNILIDKEVAFGTGTFYKQDQELVEDQVEVGFGNAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGTAKADAPVAPTSKTLIIRGDVAFGKL
                     ELVYVK"
     gene            9769..9957
                     /locus_tag="VQO19_001695"
                     /pseudo
     CDS             9769..9957
                     /locus_tag="VQO19_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647592.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein A"
     gene            10207..10506
                     /locus_tag="VQO19_001696"
     CDS             10207..10506
                     /locus_tag="VQO19_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HET1349924.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDHKLMKTQEELTA
                     IVRDHFSDMGEIATLYVQVYESSLESLLGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            10503..10820
                     /locus_tag="VQO19_001697"
     CDS             10503..10820
                     /locus_tag="VQO19_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HET1349925.1"
                     /translation="MIQPASLEELASLVEKDGKKVFLFVADWCGDCRYIYPALPEIEE
                     SNPEFTFIRVDRDQYIDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKQQINDFLA
                     GLK"
     gene            10836..11462
                     /locus_tag="VQO19_001698"
     CDS             10836..11462
                     /locus_tag="VQO19_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HET1349926.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKDKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            11495..12256
                     /locus_tag="VQO19_001699"
     CDS             11495..12256
                     /locus_tag="VQO19_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET1349927.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            12334..12729
                     /locus_tag="VQO19_001700"
     CDS             12334..12729
                     /locus_tag="VQO19_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HET1349928.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            12999..13283
                     /gene="groES"
                     /locus_tag="VQO19_001701"
     CDS             12999..13283
                     /gene="groES"
                     /locus_tag="VQO19_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HET1349929.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            13299..14921
                     /gene="groL"
                     /locus_tag="VQO19_001702"
     CDS             13299..14921
                     /gene="groL"
                     /locus_tag="VQO19_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HET1349930.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISNRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(15020..>15684)
                     /locus_tag="VQO19_001703"
     CDS             complement(15020..>15684)
                     /locus_tag="VQO19_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET1349931.1"
                     /translation="IRDHFLKYDRAVRCRVKIITMDMFSPYYGLAKQLRFHIVQHLSR
                     AMSRVRVQIMNQFHRKSHEYKAIKRYWKLIQQDSRKLSDKQFYRPTFRMHLTNKEILN
                     KLLSYSEDLKHHYQLYQLLLFHFQNKEPEKFFGLIEDNLKQSHPIFQTVFKTFLKDKE
                     KIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLS
                     RA"
BASE COUNT         4649 a         2850 c         3618 g         4567 t
ORIGIN      
        1 ggttacaggc tttatcttca actgttagcg gcttgagttt gctggattta cgtggagttt
       61 gtgcttgagg atatatcttc atgagccctt gataaccact gtcagccaag attttaccag
      121 cttgtccgac ttttttgata agctgttttt aatccagcta acatctcttc aaaagtggta
      181 cgctgaacac taacaagacg cttaaatcgt gcatcagtta gttgtttact tgcttcatca
      241 ttcatagaac tactatacca tattttgttt cgcaggaagt ctaataagtt atagtccagt
      301 ttttactata ctttgatatt caaatatgtt atactatggt tatcaaagta aatgaaagga
      361 gttacgaata tgacgccaga agaaatgtac ctgacagagc gattagacgt acagatagct
      421 cattttttaa agaaaagcgt tcaacatcgt agacgctata aggtattaaa aataacagaa
      481 atcgtggcag gtttcctcat agctgtcttt tgtgctattc ctatgccagg tgatcgctac
      541 cgtttgattt cggttgcctt atccagtctc ggcttgctgt gtgaggggat tatcaatttg
      601 tataatgcaa aggaaaattg gatttcttac caaaaaactg cgcaactcct ggagaaagaa
      661 aaattcctct atcaatgcca aacggagaaa tatgcaggaa agaccaaggc ttttgcccta
      721 tttgtcaaga catgcgaagg tcttatctca gaggagatta accagtggga aagtatccag
      781 tcaaaagaag tggcagctag tgcagatgct ccagttaaaa aagagtagga ggtagaggaa
      841 atgtctcaat ccagctacct gtcgcccttg ctctggttaa aaaaagaagc cgataaggaa
      901 aagatgagcg cgacccagtg ccagatattt ttcttttact atcaaatgtt tgagctctta
      961 tttgctagag aaagcgacat gaaagactta tgtctgggaa cgaaaggttt ttatttctcg
     1021 cagttagaga aaaatttgct ttctggagtt tcccgatttc taaaaaactt ggaggggaaa
     1081 gtaactctca aggctaacca agaagtatca gctcgcaaag ccctttttct agccttgaca
     1141 actagccaat cagattggca ggagttagct cctgtttttg atttttatca gactatcggg
     1201 aggcttgaaa atccttctct cttgagttct caggacagac aacatctgat gtggatttac
     1261 cagtcagctt tggagaagga ttatattgtc aaggttattg gcgacaagca ttttgtattg
     1321 aagagacaag atgctactaa attgacagcg cgccaaactc aaactttgga aattctgagt
     1381 caatcagaag acttggtcaa tcctgtctat gttacattag gagaaaaggg ggtgctcttg
     1441 cttgattaag agaggagatg ttgtagctct ttatttgcct tttccgacta ttagtagcga
     1501 tttggctgtg aagaatcata tgtatatctg tattgacaac agcatgacta aaaacaaaga
     1561 gttggttaaa aatcagacct tcaaaccagc tctcttgacc agacgtttgg tcaagaactt
     1621 tatgatagaa gagccggatc tagctcgtaa tccttttaca agaccaacct tgattgactt
     1681 agataaggta tttatgttgg ataatacggt tattccgact tcttatctag ccagacggcg
     1741 acgcaatgtc tcagaagaat tgtacgagga aattttggat cacttagtcc aaccacggct
     1801 gatttcgctg aacaagtctg agtttatgca actcaatcca ggaacttatt aggaggtaga
     1861 agatggcaaa taaagcagta aatgacttta tactagctat gaattacgat aaaaagaaac
     1921 tcttgaccca tcagggagaa agtattgaaa atcgtttcat caaagagggt aatcagctac
     1981 ccgatgagtt tgttgttatc gaaagaaaga agcggagctt gtcgacaaat acaagtgata
     2041 tttctgtaac agctaccaac gacagtcgcc tctatcctgg agcacttctc gtagtggatg
     2101 agaccttgtt agagaataat cccactcttc ttgcggtcga tcgtgctccg atgacttata
     2161 gtattgattt gcctggtttg gcaagtagcg atagctttct ccaagtggaa gaccccagca
     2221 attcgagtgt tcgcggagcg gtaaacgatt tgttggctaa gtggcatcaa gattatggtc
     2281 aggtcaataa tgtcccagct agaatgcagt atgaaaaaat cacggctcac agcatggaac
     2341 aactcaaggt caagtttggt tctgactttg aaaagacagg gaattctctt gatattgatt
     2401 ttaactctgt ccattcaggc gaaaagcaga ttcagattgt taattttaag cagatttatt
     2461 atacagtcag cgtagatgct gttaaaaatc caggagatgt gtttcaagat actgtaacgg
     2521 tagaggattt aaaacagaga ggaatttctg cagagcgtcc tttggtctat atttcgagtg
     2581 ttgcttatgg gcgccaagtc tatctcaagt tggaaaccac gagtaagagt gatgaagtag
     2641 aggctgcttt tgaagctttg ataaaaggag tcaaggtagc tcctcagaca gagtggaagc
     2701 agattttgga caatacagaa gtgaaggcgg ttattttagg gggcgaccca agttcgggtg
     2761 cccgagttgt aacaggcaag gtggatatgg tagaggactt gattcaagaa ggcagtcgct
     2821 ttacagcaga tcatccaggc ttgccgattt cctatacaac ttctttttta cgtgacaatg
     2881 tagttgcgac ctttcaaaac agtacagact atgttgagac taaggttaca gcttacagaa
     2941 acggagattt actgctggat catagtggtg cctatgttgc ccaatattat attacttggg
     3001 atgaattatc ctatgatcat caaggtaagg aagtcttgac tcctaaggct tgggacagaa
     3061 atgggcagga tttgacggct cactttacca ctagtattcc tttaaaaggg aatgttcgta
     3121 atctctctgt caaaattaga gagtgtaccg ggcttgcctg ggaatggtgg cgtacggttt
     3181 atgaaaaaac cgatttgcca ctagtgcgta agcggacgat ttctatttgg ggaacaactc
     3241 tctatccgca ggtagaagat aaggtagaaa atgactagga gaagagaatg cttgcgacaa
     3301 aaagaggcga tgatctctct gcggatatct gaaagtttat ctcttgccta gcgatttcca
     3361 ttggagtatg ctcgtgatgt taaaatgagt ctatcaaaca ggatgtgtaa aaaagtaaaa
     3421 agggtagcca attccttgat atacagggga ttgattatcc tttacttgtt ttagatgatt
     3481 ggaaattcaa gaatgacacg tatcggaaat attttgctgt ttatatctaa tacccattta
     3541 tggaaaaaat gaaattaaat atgaacaaat caattgctag caatggttta gaagtgccag
     3601 tgtactagtc taacttctcc atcttgggaa cacgtaaatt atactcttcg aaaatctctt
     3661 caaaccaggt cagccctatc cgcaacttca aaacagtgtt ttgagcaccc tgcggctagc
     3721 tttctggttt gttctttgat ttttattgag tattagaggt ttgcttagaa actcttctat
     3781 tgatttctta gaatacaata gcgcctataa gaactgttgg atttcaaagt atttacttga
     3841 actatgatat gtctggagta gactgtcaac aaaaggtgca gtatgattgt ttttgtcgct
     3901 tatatctaca aacttcaaac agtaatttga gctgactttg tcaaacttgg ctgaaacttt
     3961 ctatttgcag ataatggtct agtttgtttt ttgaatgtgg atgagtgtct gttgataaag
     4021 atagaaaggc aagaccgtct tagcaggtaa agtgctatcc tagcttgatt tgctaataaa
     4081 atccatttcc tctagtgaaa atcaaaaaaa cttgtgttat aataagaaag attaaaatgt
     4141 gaaaaaagga gattcctaat gggacgtaaa tgggccaata tcgtagccaa gaaaacggct
     4201 aaagatggag ccaactctaa agtatatgca aaatttggtg tagaaatcta tgtagcagct
     4261 aaaaaaggtg atccagatcc agaatcaaac tcagctttga aattcgttat cgaccgtgct
     4321 aaacaagccc aagtgccaaa acacattatc gataaagcga ttgataaagc caaaggaaac
     4381 acagacgaaa cctttacaga aggacgttac gaaggttttg ggccaaatgg ctctatgcta
     4441 attgtggata ctttgacttc taacgttaac cgtacagcag ccaatgtccg tgcagccttt
     4501 ggtaaaaacg gcggaaacat gggcgcttca ggttctgttt cttacctttt tgacaacaaa
     4561 ggtgttattg tatttggagg tgaagatgcg gacgcagtct ttgagcaatt gctcgaagcg
     4621 gatgtggatg tggatgacgt agaagcacaa gaaggtacaa tcacagttta cacagcgcca
     4681 actgaccttc acaaggctat cgttgccctc cgtgagtctg gtattgaaga attccaagtg
     4741 actgaattgg aaatgattcc tcagtcagaa gtggaattgt caggcgaagc ccttgaaacc
     4801 tttgaaaaac tttacagcgt tcttgaagac gacgaagacg tccaaaagat ttatacgaac
     4861 gtagatgggt tttaatttaa cctatagaac atgatcctaa gtgagaaaat cacttgggat
     4921 ttttttaatc aagaaaatag ttctcataga aatttaatta ttctccagag aactattttt
     4981 atttagaagg gggagattat ggataaaccg atgttagtct ttaagcgttt tggtcatcaa
     5041 attcacctga tggtgcaaaa ggaagccaaa cgttgcggca ttgaatttat gggtgggcgg
     5101 caaggtcagg ttgtgcattt tttggataat cgcgagaaaa accaagactt ggtcttgatt
     5161 aaagatatcg agcaggaact caatattacc aagtctgttg ctagtaatct ggttaagcgt
     5221 atagtgcaaa atggtttggt ggaattggag gcgagtcctg ttgataagcg ggctaagttt
     5281 gttcgtctga cggacaaagc acgttctcag atacaacagg ttaaggcttt ttttgaacgc
     5341 atagacaagc agttgatgga agacattgat gaagatgaat tactgatttt tgagaaagtt
     5401 ctcggtcaac tacaggcaaa tatcaaggga ataggaggag agaataaaga aattagccaa
     5461 aagaattagt agaaaagaat gggggatgat tttactagcc attctcttta cttgcttttc
     5521 ggtctatcta gagttggaag tgccgaccta tatctcgaaa attacggatt tgctaggtag
     5581 tcaaggaact aatttagatg agttgtggca gccggcaagc atgatgatgg gaatgccctt
     5641 tcttgccttc ttgtccgtag ttgcagttgg attttttgca tcccgagtgg cggcttctta
     5701 tactagtagg ctgagaagtg atatttttaa ccgagttttg gattactcgc agacagagat
     5761 taagaaattt tcaattccta gcctcttgat gcgtactacc aatgacatta ctcaagttca
     5821 aatgttgatt actatgggct tgcaagtggt aacgtgtggt ccaattatgg ctatctgggc
     5881 tattgggaag attttaggtc attcagaata ctggctctgg gccgtacttg tggcagtgat
     5941 tgtcaacgtc ctgatgacga ccgttttgat gacgctagcc tttccaaaac agtccttgat
     6001 tcaggggctg acagataaac tgaacagtat cactcgtgag agtttaacag gtattcgtgt
     6061 cgttcgtgcc tacaatgcag aggattatca aaatgaaaaa tttgcagcag taaatgatga
     6121 attgacccgt ttaaatttgt ttgtcaaccg tcttatggct attttgaatc ctatcatgat
     6181 ggggatttca agtggtttga gtgtggcgat ttactggatt ggggcctatg tgattaacga
     6241 cgctgctccg atagcgcgtc tgcctctctt tagtgacatg attgttttca tgtcttatgc
     6301 catgtaggtt gtcatggact tccttctcat gggagcactc ttcatcgttc ttccccgaac
     6361 tatggtctct gctaagcgga ttaatcaagt tttagatttg cattcttcta tccaaaaccc
     6421 tgttcaagta cagctgactg atgaaaactt caaaggtcag gtcgagttta aggatgtgac
     6481 cttccgctat gcggcaaatt cggaggcagt tattgaacat gttagcttta aagcagaaac
     6541 tggtcaaaca gtggccttta ttgggtcaac aggttctggt aaatcaactc tggtcaatct
     6601 gattccacgt ttctacgacg tgtcagcagg agaaattctg gtggacggtg tcaatgttca
     6661 agactatgac ttctctgcga cagctcatgc tggtcaaaag gttgccattg ttgggccgac
     6721 tgggactggt aagacaacca ttgtcaatct tttgatgaaa ttctatgaga ttgataaggg
     6781 aagtattcac attgatggtg tggataccaa ggctatgacg cgttcagaag tgcatgatgc
     6841 cttttcaatg gtcttgcagg atacctggct ctttgaagga actattcgag acaatctcat
     6901 ctataatcaa atagggatta gtgatgaacg aatgatggaa gctagtaagg ctgtgggaat
     6961 tcaccacttt attatgacct tgccagatgg ctatgatacc atcttggatg acaccgtgac
     7021 cttgtctgta ggacaaaaac aactattgac tattgctcgt gcccttctta aggatgcacc
     7081 gcttttgatt ttggatgagg cgacttcttc tgttgacaca cggacagagg aattgatcca
     7141 aaaagccatg gaccgtttga tggaaggacg cacatccttt gtcattgccc accgcttgtc
     7201 aaccatccga aatgcagact tgatcttggt catgaaagat ggaaatatca tcgagcaagg
     7261 caactatgag gaactgatgg cgcaaggtgg cttctacgct gacttgtaca atagtcaatt
     7321 tacagaagat gaagcagaag aataaatcaa aagaaggctt gacggccttc tttttcttat
     7381 ttatactagt acacatagaa agagagaagt atgagtcaga aattatacaa tatgaaattt
     7441 gctgctgtct acttagcctt gattgcaaaa gttgagcgaa agggtggaaa ggcagagtca
     7501 gttcaccaag tgaccagttg gttgacaggg tatgaagtga gtgatgttct tgcttgtctg
     7561 gatagggatg ttacttacgg agattttttt agacaagcac catattatgt ccctgaacga
     7621 attgcaatta cagggaagat ttgcggtgtc cgtattgagg aaattgatga tcctctgatg
     7681 caggaaatac gtcgcttgga caagctagtg gattggcttg ccaaggggaa aacatctcaa
     7741 caagttctag aaaagtatga gaagcataaa tgaaaaatta tcaagaatgg tatcgaaata
     7801 tcagctccag actaactagt cgtccaattc ttttattcct attacgcagt ttcaatcgtt
     7861 tgatgacagt cgccatgccc ctggtctatc tgatcttgct agtcaccact tacctgcaac
     7921 taggacttgg tcagcaagtt ggggtttatg tgcttattcc tgcatcaggt tttgtggcct
     7981 tgtccctgtt tcgtaagaaa atcaatcacc cgagacctta tgaaacttgg gatatctgtc
     8041 cccttcttga taaggatagt gcgggacggt cgatgcccag tcgccatgtc ttttcggcaa
     8101 ctatcatctc catggcctgt ctgcatgcta gtctacctat tggcttagta tgcttgatct
     8161 tttcagcttt gctggggttg gtgagggttt tagggggtgt tcattatccc aaggatgtct
     8221 tggttggcta tgcttgtggt ttggtgtggg gattcctttt cttcctattc tgacatgtaa
     8281 gttaagctag tcctacaacc acttactgct tcaaattgac cacttgcttt tttgcccttg
     8341 tattcctaac ttagctttga tatagtagag tcagaaagga gatgtgatga agttacgaat
     8401 tgagattgac ggcaatttag aggagactga aattgtcatc aagaccccca ctttgacaga
     8461 tgaaattgca gacttgcaac ggctcttgca agagtcaaag gctccgaggt tgacttttta
     8521 caaggggaca ggtgaatatt atctagacct gtcagaaatt ctcttctttg aaacagaagg
     8581 gagcaagatc tacgctcata accagaagga agcttatgag gttcgcctca agctctatga
     8641 gttggagtct atcttgcctc gctattttaa tcgagtttcc aagtcaacga tcgcaaacat
     8701 ccgtcagatt tactcagtgg acaagtcctt ttcaggaacg ggcaccattt ccttttatca
     8761 gacgcacaag gaggttcatg tctcacggca ttaccaatcc ctcctaaaag aaaatctaag
     8821 aaacatgagg taaaaaacat gaaaaagaaa gcatttggta ttgtgttact tgtactagca
     8881 gctttaatat tagtacaagg aaattttgga atcccttctc taggagggca catttggccc
     8941 ttgattggta ttgctttttt tgcctaccaa tcagttggag ctttgttgcg tcgccactta
     9001 acttcagcct cttttacagc tctagtatcc ttaatgattg ctaaccactt ttatggcatt
     9061 ttaccgattc caaaccagac actaatctgg gcaggagttc taatcgttct cggagtaaat
     9121 atgttgactc attctaacag aacttggaat gggaaaaaat ggtggtatga tggtgaaaaa
     9181 aacattctta tagataagga agttgctttt gggacaggga ctttctacaa gcaagaccaa
     9241 gaattggtag aagaccaagt agaagttggt tttggcaatg caaaaatcta ctatgacaat
     9301 gcagagatgt taggtgattt tgcaacttta aatattgaag tagcttttgg taatgcaact
     9361 gtctatgttc cgcaacactg gcgtgtcgat ttgaaagtag aaacatcctt tggtacagcc
     9421 aaggcggacg ctcctgtagc gccaacaagc aaaaccttga ttattcgtgg agacgtggcc
     9481 tttgggaagt tggagcttgt ctacgttaaa taaaaaaatc ttcacttaaa ccatcaaaat
     9541 agacgtacta agagtaggaa attgatgcct tgctctgatt tcagttctat ggttgttaga
     9601 ctttaaaaaa tgaaatgttg cctttaaaag ttgtatattt ttcgatattt tgactcttac
     9661 gtttgatgta tctatgtcct acagcgtgga tgatgtagtg taaaatgctt taaaaaaaaa
     9721 atgaatgata ttggacagtt tttttgaact tttaattgct caggagccat gaaagcaagc
     9781 gcttgggttt atgacaaggg agaatggtat tatgtaagtt cttctggttc catgattgcg
     9841 aatgattggg tcaaagacaa tggcaagtag tattatctgg cttcatcagg taagatgctt
     9901 cgcaatacct acacacctga tagttactac gttggcaact taggtgcctg gcaataagaa
     9961 taatactctt cgaaaatctc ttcaaaccac gtcagcttca tccacaacct caaaacagtg
    10021 ttttgagctg acttcgtcag ttctatctac aacctcaaag cagtgctttg agcagcctgc
    10081 ggctagcttc ctagtttggt ctttgatttt cattgagtat aagaagtcct tttccttaaa
    10141 ggaagaggct ttttacttgc ttttttgctg tttcctcatt tgtcctaaag ccttttttgt
    10201 gttaaaatga atggtatgaa agctaaaaaa atgtggatgg caggtctggc tctgcttggt
    10261 attgggagcc ttgcccttgc tacgaaaaaa gttgcagatg accataagct catgaagact
    10321 caggaagagt tgacagcgat tgtacgagac catttttcag acatggggga aattgcgacc
    10381 ctctatgttc aagtctatga aagcagtcta gagagcttgc ttggtggcgt tatttttgag
    10441 gatggccgtc attatacctt tgtctatgaa aatgaagacc tagtctatga ggaggaagtc
    10501 ttatgataca accagcaagt ttagaagaat tggcatcttt agtagaaaaa gacggtaaga
    10561 aggtcttcct ttttgtggcg gactggtgtg gcgattgccg ttatatctat cctgccttac
    10621 cagaaattga ggagagtaat ccagagttta cctttattcg agtggataga gaccagtata
    10681 tagatttggc caaactctgg gatgtatatg gaatccctag ccttgttgtt ctagaaaagg
    10741 acaaggaaat cggtcgtttt gtcaatcgcg accgtaaaag caagcaacaa attaacgatt
    10801 ttttagcagg attgaaatag gagaaaaagg aaacaatgat ttttacatat aacaaagaac
    10861 atgtcggtga tgtccttatg gtcatcgtga aaaatagcgg agatgctaaa ctgaatgtgg
    10921 aacgcaaaga caaggtagcc cgtgttttcc tcaaagaaaa tggggaaaca gtagcttgga
    10981 acatttttga ggtttcgagc ttgtttgaaa ttgcagagcg cggtcaagtc tttttatcag
    11041 atgagcaagt cgctcgtttg aaccaagaat tacaggcgga aggttttaca gaagaaattg
    11101 ttaatgataa ggaacctaag tttgttgttg gtgaaattgt cgagatggta gctcatccag
    11161 acagtgacca cctcaacatc tgccaagttg cagtcgcaag tgacaagata gtgcaaatcg
    11221 ttgcaggagc acctaatgcg cgtgttgggt tgaaaaccat tgtggctctt cctggtgcca
    11281 tgatgccaaa agggaatttc attttcccag gcgaacttcg tggtgaaaag agttttggga
    11341 tgatgtgtag tcctcgtgaa ttgcatttgc caaatgctcc gcaaaaacgt ggggtgcttg
    11401 aattatcaga agaccaagtt gtcggaacac cgttcgaccc agcgaaacac tggactgcct
    11461 aggaacttgt cagcatctga tagaaggaaa taagatggca aaaaatgtag tgattacggg
    11521 agcaacctca ggaatcggtg aagcgattgc gcgtgcttat ctggagcagg gtgaggatgt
    11581 cgttctaaca ggacgacgga tagacagatt agaaatcctc aagtcggagt ttgcagtaag
    11641 ctttccaaat caaaccgtct ggacttttcc actagatgtg acggatatgg tcatggtgaa
    11701 gactgtttgc tctgatattc tagaaacgat agggaggatt gatatcttgg tcaacaacgc
    11761 cggactggct cttgacttgg ctccctatca agactatgag gagttggata tgttgaccat
    11821 gttggatacc aatgttaaag gtctgatggc ggttactcgc tgtttcttgc cagcaatgat
    11881 aaaagtcaat caaggtcata ttatcaatat ggggtcaacc gcaggaatct acgcctatgc
    11941 tggtgccgct gtttactcag ctaccaaggc agcggttaag accttttcgg atggactgcg
    12001 aattgatacc atcgcaacgg atatcaaggt gacaaccatt cagcctggga ttgtcgaaac
    12061 agatttctca actgttcgtt ttcatggtga taaagagcgg gctgcgtccg tttaccaagg
    12121 aatagaagcc ttgcaagctc aggatattgc agacacagta gtctatgtga ccagtcagcc
    12181 tcgccgtgtt cagattacag atatgaccat tatggccaat caacaggcga caggtttcat
    12241 gattcataaa aaataagaaa tttcctcgaa aagttacaaa tttctgtaac tttttttgat
    12301 ttcctacgaa tagataagta ggaggaagaa aatatgtata ataaagttat catgattggg
    12361 cgtttaacgt ctacaccaga attgcacaaa accaacaatg acaagtcggt agcgcgagca
    12421 actatcgctg tgaaccgtcg ttacaaagac caaaacggtg aacgtgaagc tgattttgtc
    12481 aatatggtcc tatggggcag actagcagaa actttggcaa gctacgcaac caaaggtagt
    12541 ctcatttccg ttgatggaga attgcgtacc cgtcgctttg agaaaaatgg ccaaatgaac
    12601 tacgtgaccg aagtacttgt cacaggattc caactcttgg aaagtcgtgc tcaacgtgct
    12661 atgcgtgaaa ataatgcagg ccaagatttg gcagatttgg tcttggaaga ggaagaattg
    12721 ccattttaat actcttcgaa aatctcttca aaccacgtta gctttatcca caacctcaaa
    12781 gcagtgcttt gagcagcctg cggctagctt cctagtttgc tctttgattt tcattgagta
    12841 taaacattaa aaagtctgag ttggtctcag gctttttatc ttgagaaagt cagacttttt
    12901 tcttgactat ttctgaccaa gtgatacaat agaattatga attagcactc aagttcaaag
    12961 agtgctaata atatctatct cattatggag gaaatcagat gttgaaacca ttaggggacc
    13021 gtgtggtctt aaaaatagaa gaaaaagaac aaaccgttgg gggctttgtc cttgcaggct
    13081 cagcccaaga aaaaaccaaa acagctcaag ttgtggctac tggacaaggt gttcgtacct
    13141 tgaacggtga cttggttgct ccaagtgtta aaactggaga tcgtgtctta gttgaagccc
    13201 acgcaggtct tgatgtcaaa gatggcgatg aaaagtacat catcgtaggc gaagctaaca
    13261 ttttggcaat cattgaggaa tagaaggaga aagtaagtat gtcaaaagaa attaaatttt
    13321 catcagatgc ccgttcagcc atggttcgtg gtgtcgatat tcttgcagac actgttaaag
    13381 taaccttggg accaaaaggt cgcaatgtcg ttcttgaaaa gtcattcggt tcacccttga
    13441 ttaccaatga cggtgtgacc attgccaaag aaatcgaatt ggaagaccat tttgaaaata
    13501 tgggtgctaa gttagtatca gaagtagctt ctaaaaccaa tgatatcgca ggtgacggga
    13561 ctacgactgc aacagtcttg acccaagcta tcgtccgtga aggaatcaaa aacgtcacag
    13621 caggtgcaaa tccaatcggt attcgtcgtg ggattgaaac agcagttgcc gcagcagttg
    13681 aagctttgaa aaacaacgcc atccctgttg ccaataaaga agctatcgct caagttgcag
    13741 ccgtatcttc tcgttctgaa aaagttggtg agtacatctc tgaagcaatg gaaaaagttg
    13801 gcaaagacgg tgtcatcacc atcgaagagt cacgtggtat ggaaacagag cttgaagtcg
    13861 tagaaggaat gcagtttgac cgtggttacc tttcacagta catggtgact gatagcgaaa
    13921 aaatggtggc tgaccttgaa aatccgtaca ttttgattac agacaagaaa atttccaata
    13981 tccaagaaat cttgccactt ttggaaagca ttctccaaag caatcgtcca ctcttgatta
    14041 ttgcggatga tgtggatggc gaggctcttc caactcttgt tttgaacaag attcgtggaa
    14101 ccttcaacgt agtagcagtc aaggcacctg gttttggtga ccgtcgcaaa gccatgcttg
    14161 aagatatcgc catcttaaca ggcggaacag ttatcacaga agaccttggt cttgagttga
    14221 aagatgcgac aattgaagct cttggtcaag cagcgagagt gaccgtggac aaagatagca
    14281 cggttattgt agaaggtgca ggaaatcctg aagcgatttc taaccgtgtt gcggttatca
    14341 agtctcaaat cgaaactaca acttctgaat ttgaccgtga aaaattgcaa gaacgcttgg
    14401 ccaaattgtc aggtggtgta gcggttatta aggtcggagc cgcaactgaa actgagttga
    14461 aagaaatgaa actccgcatt gaagatgccc tcaacgctac tcgtgcagct gttgaagaag
    14521 gtattgttgc aggtggtgga acagctcttg ccaatgtgat tccagctgtt gctaccttgg
    14581 aattgacagg agatgaagca acaggacgta atattgttct ccgtgctttg gaagaacccg
    14641 ttcgtcaaat tgctcacaat gcaggatttg aaggatctat cgttatcgat cgtttgaaaa
    14701 atgctgagct tggtatagga ttcaacgcag caactggcga gtgggttaac atgattgatc
    14761 aaggtatcat tgatccagtt aaagtgagtc gttcagccct acaaaatgca gcatctgtag
    14821 ccagcttgat tttgacaaca gaagcagtcg tagccaataa accagaacca gtagccccag
    14881 ctccagcaat ggatccaagt atgatgggcg ggatgatgta agctttctat agaaaacaac
    14941 ttataaaaaa cacaaaagga gggaatgact aacccttctt tttataggct ctttgtcaac
    15001 tgtagtgggt tgaagtcagc taagctcgag aaaggacaaa ttttgtcctt tcttttttga
    15061 tattcagagc gatgaaaatc cgttttttga agttttcaaa gtttcgaaaa ccaaaggcat
    15121 tgcgcttgat aagtttgatg agattattgg tcgcttccag tttggcatta gaatagtgta
    15181 gttgaagggc gttgacaatc ttttctttat ctttgaggaa ggttttaaag acagtctgaa
    15241 aaataggatg agactgctta agattgtcct caataagtcc gaaaaatttc tctggttcct
    15301 tattctggaa gtgaaacagc aagagctgat agagctgata gtgatgtttc aagtcttccg
    15361 aatagctcaa aagcttgttt aaaatctctt tattggttaa atgcatacga aaagtaggac
    15421 gataaaattg cttatcactc agtttacggc tatcctgttg aatgagtttc cagtagcgct
    15481 tgatagcctt gtattcatgg gattttcgat gaaactgatt catgatttgg acacgcacac
    15541 gactcatagc acggctaaga tgttgtacaa tgtgaaagcg aagctgttta gccaagccat
    15601 agtaagggct aaacatatcc atagtaataa ttttgacgcg acatcggacg gctctatcat
    15661 atttaagaaa gtgatctcgg atga
//
LOCUS       DAVAGB010000047        14037 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVAGB010000047 DAVAGB010000000
VERSION     DAVAGB010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14037
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.047"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            81..878
                     /locus_tag="VQO19_001704"
     CDS             81..878
                     /locus_tag="VQO19_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HET1349932.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLIHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1026..1148
                     /locus_tag="VQO19_001705"
     CDS             1026..1148
                     /locus_tag="VQO19_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HET1349933.1"
                     /translation="MTRDFKFETLQLHAGQVVTPATKSRAVPIYQTTSFVFDDT"
     gene            1170..2210
                     /locus_tag="VQO19_001706"
     CDS             1170..2210
                     /locus_tag="VQO19_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HET1349934.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETLG
                     NPLINIPDLEKLAEIAHKHQIPLVSDNTFATPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFPQFVDEGPSCHNLSYTRDVGAAAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETSSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKGVGSIFTFHVKGGEEEARKVIDNLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            2381..3655
                     /locus_tag="VQO19_001707"
     CDS             2381..3655
                     /locus_tag="VQO19_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HET1349935.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLAHNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3665..4543
                     /gene="truB"
                     /locus_tag="VQO19_001708"
     CDS             3665..4543
                     /gene="truB"
                     /locus_tag="VQO19_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HET1349936.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGLITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4784..5086
                     /locus_tag="VQO19_001709"
     CDS             4784..5086
                     /locus_tag="VQO19_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET1349937.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5194..5832
                     /gene="udk"
                     /locus_tag="VQO19_001710"
     CDS             5194..5832
                     /gene="udk"
                     /locus_tag="VQO19_001710"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HET1349938.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5960..7300
                     /locus_tag="VQO19_001711"
     CDS             5960..7300
                     /locus_tag="VQO19_001711"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HET1349939.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RIATAVRNVLSKKQETLKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESIVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7278..7490
                     /locus_tag="VQO19_001712"
     CDS             7278..7490
                     /locus_tag="VQO19_001712"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HET1349940.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7487..8362
                     /locus_tag="VQO19_001713"
     CDS             7487..8362
                     /locus_tag="VQO19_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HET1349941.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8355..9170
                     /locus_tag="VQO19_001714"
     CDS             8355..9170
                     /locus_tag="VQO19_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HET1349942.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEV
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9163..9594
                     /locus_tag="VQO19_001715"
     CDS             9163..9594
                     /locus_tag="VQO19_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET1349943.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIDTFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9601..11268
                     /gene="recN"
                     /locus_tag="VQO19_001716"
     CDS             9601..11268
                     /gene="recN"
                     /locus_tag="VQO19_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HET1349944.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDSEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNKMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11270..11998
                     /locus_tag="VQO19_001717"
     CDS             11270..11998
                     /locus_tag="VQO19_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HET1349945.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12077..13900
                     /gene="lepA"
                     /locus_tag="VQO19_001718"
     CDS             12077..13900
                     /gene="lepA"
                     /locus_tag="VQO19_001718"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HET1349946.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
BASE COUNT         4149 a         2568 c         3351 g         3969 t
ORIGIN      
        1 ttttatgaaa tacagaaaac gcttcctaaa acctaaagtt tgtgatataa ttatcaagaa
       61 aaaagattta ggagtttatt atggtttctt cggaatttat ctcaaagatt gaatttgctt
      121 gcaataagaa agaaagtctt tatagtcaaa gcaaatttaa gtatgcgatt cgttcgatgt
      181 tcgcaggtgc atttttaacc ttcagtactg ctgcaggtgc agttggagct gacttgatta
      241 ataaaattgc accaggtagt ggacgcttcc tctttccatt cgtttttgct tggggcttgg
      301 cctacattgt ttttttgaat gccgagttgg tcacttcaaa catgatgttc ttgactgctg
      361 gtagtttctt aaaaaaaatc tcttggagaa aaacagctga gattttacta tactgtacct
      421 tgttcaacct tatcggagcc ttgatagcag ggtggggctt tgctcattcg gcagcctatg
      481 cgaatctgat acacgatagt ttcatctcag gtgttgttga gatgaagtta ggccgctcaa
      541 atgaattggt cttgcttgag gcgattttgg caaatatttt cgtaaatatt gcgattctgt
      601 catttatttt ggtcaaagat ggtggtgcca aactttggct tgtgttgtca gctatttaca
      661 tgtttgtatt cttaacaaac gagcacattg cggcgaactt tgcttctttc gcgattgtga
      721 aattcagtgt tgctgcggat tcaattgcca acttcggtgt tggaaatatg cttcgccact
      781 ggggtgtgac tttcatcgga aactttatcg gaggaggcct cttgatgggt cttccatatg
      841 ccttcctcaa taaaaacgaa gatacttatg tagattaaga aaatgagcac gattgagtcg
      901 tgcttttttc attttcaaaa taagataata gctatttctt atatcaaaat atagaaaact
      961 gatatttgta aactataact caaggtgcta caatatcctt aataaaataa tatggaggtc
     1021 accttatgac tcgtgatttt aaatttgaaa ctctacaact acatgctggt caagttgtga
     1081 ctccagctac taagtctcgt gcagtgccga tttatcaaac aacatctttt gtttttgatg
     1141 acacgtagga aggtgctgat ctgtttgcct tgaggaaacc agggaacatt tatactcgta
     1201 tcaccaatcc tacaacagct gcccttgaag gtggtgttga agcgctagca acagcatcag
     1261 gtatgactgc agtgacttat acgattttgg cgcttgccca tgctggtgac catgtagtgg
     1321 ctgcttcgac tatttacggt ggaaccttca atcttttgaa agaacccctt cctcgttatg
     1381 gtatcacaac aacctttgtc gatgttgata atttggagga agtagaagca gctatcaaag
     1441 acaataccaa gcttgtcttg attgaaacct tgggtaaccc cttgattaat attccagacc
     1501 tggaaaaact ggcagagatt gctcataaac atcaaatccc acttgtgtca gacaatactt
     1561 ttgcaacacc ttatttgatt aacgtcttct ctcatggcgt tgacattgcc attcactctg
     1621 cgactaagtt tatcggtggg catggtacaa ctattggagg aataattgtc gatagtggtc
     1681 gttttgactg gacggcttca gggaaattcc ctcaatttgt tgacgagggt ccaagctgcc
     1741 acaatttgag ctatactcgt gatgtgggtg cagcagcctt tattatagct gttcgagttc
     1801 aattgcttcg tgatacaggt gcagccttgt caccattcaa tgctttcctc ttgctacaaa
     1861 gacttgaaac ctcttcactt cgtgtggaac gccatgtaca aaatgctgag acaattgttg
     1921 attttcttgt caaccatcct aaggtagaaa aggtaaatta tccaaaactt gcagatagtc
     1981 cttatcatgc cttggctgag aaatacttgc caaaaggtgt cggttcaatc tttaccttcc
     2041 acgtcaaagg tggcgaggaa gaagcacgca aggtcattga taatttagaa atcttttctg
     2101 accttgcaaa cgcggcagat gctaaatcgc ttgttgtcca tccagcaaca accactcacg
     2161 gtcaattgtc agaaaaagac ctagaagcag caggtgtcac accaaactaa attcgtttgt
     2221 caatcggtct tgaaaatgta gaagatttga ttgaagactt gcgcttggcc ttggaaaaaa
     2281 tttaaagtaa aagaagataa acagtgggct tcgactcact gtttttgatt ttccctcagg
     2341 catgatataa tggttaaaga agtctagaaa gaggaacgat atgaacgaaa tcaaatgtcc
     2401 caactgtggg gaagtcttta cagtaaatga gagtcagtat gccgaactct tgtcccaagt
     2461 gagaacggca gagtttgata aggaactaca cgataggatg aagcaggaac tggccttggc
     2521 tgagcaaaag gccatgaatg agcaacagac taaactggct cagaaggatc aagaaattgc
     2581 gcaattgcag agtcaaatcc aaaactttga tacagaaaaa gaattggcca agaaagaagt
     2641 tgaacagaca agccatcagg ccttattggc taaggacaag gaagtacagg ccttggaaaa
     2701 ccagttggcg accttgcgtt tggagcatga aaatcaactg caaaagaccc tttctgacct
     2761 agaaaaagaa cgcaatcagg tcaaaaatca gctcctactg caagaaaagg aaaatgagtt
     2821 gtctttggct tctgttaagc aaaactacga agcccagctc aaagcagcca gtgaacaagt
     2881 cgagttttat aagaatttta aggctcaaca atctacaaaa gcgattgggg aaagcctaga
     2941 acagtatgca gagagtgagt ttaacaaggt ccgtagtttc gcctttccaa atgcttactt
     3001 tgagaaggat aacaaggtct cttcgcgtgg gtctaaaggg gactttatct tccgtgagtg
     3061 tgatgaaaat ggagttgaaa tcatttctat catgtttgag atgaaaaacg aagcggacgg
     3121 aacagagaag aagcacaaga atgcagattt ttacaaggaa ttggacaagg accgtcggga
     3181 gaagaactgt gagtatgccg ttttggtgac catgcttgag gccgataatg actactttaa
     3241 cacagggatt gttgacgtca gccacgagta tgaaaaaatg tatgttgttc gtcctcaatt
     3301 ctttatccag ttgattggtc tcttacgtaa tgcggcgcta aattccctaa aatacaagca
     3361 ggagttggcc ttggttcgcg agcaaaatat tgacattacg cattttgagg aagatttgga
     3421 tgcctttaag ctagcttttg ctaagaacta taattcagct tcgactaact ttggaaaagc
     3481 tattgatgaa atcgacaagg ccatcaaacg catggaagag gttaagaaat tcctgactac
     3541 atctgaaaac caactccgtc tagctcacaa caaattggaa gatgtctctg ttaaaaaatt
     3601 gacccggaaa aatccaacaa tgaaagcgaa gttcgaagca ctgaaggggg agtagaaagc
     3661 aaaaatgaac ggtattatca acttaaaaaa agaagcagga atgacctcgc atgatgcggt
     3721 ttttaaactg cgtaagattt tgggaaccaa gaaaattggt catggtggaa ccttggatcc
     3781 ggatgtggtg ggtgttttgc cgattgcggt tggcaaggcg acacgcatgg tcgagtttat
     3841 gcaggacgag ggtaagatct atgaggggga aattactctg ggctattcca cgacgactga
     3901 ggatgctagt ggggaagtga tcgcagaaac ccctgttttg tctcccttgg atgaaaagct
     3961 tgttgatgaa gcgattgcta gcttgactgg gcttattact cagattcccc ctatgtattc
     4021 ggcagttaag gttaatggtc gcaagctcta tgagtatgcg cgtgctggtc aggaagtgga
     4081 gcgtccagaa cgtcaggtga ccatttatca atttgagcga acaagtccga tttcttatga
     4141 tggccaactt gctcgattca cttttcgtgt aaaatgcagt aaagggactt acatccgtac
     4201 tttgtcagtt gatttgggtg aaaagcttgg ttatgcggct catatgtccc atttgactcg
     4261 tactagtgct gctggcttac aattagaaga cgctcttgcc ttggaggaaa ttgctgaaaa
     4321 agtagaggct gggcaattag attttctcca tcctttagag attgggacag gtgaccttgt
     4381 caaagttttc ctaactccag aagaggctac agaagttcgc tttggtcgtt ttattgagct
     4441 agaccaaacg gacaaagaac tggctgcctt tgaagatgat aaattgttag ccattctaga
     4501 aaaacggggc aatctctata agccaaggaa ggtttttagc tagatcgttt aggaataaaa
     4561 atcgggtgat agataacaat tgcttgataa aacctcatac taatagtaga atggttttgg
     4621 gaattataat attccaattg ttgcgagttg taggtactca aataatctat atagaaattt
     4681 agaggtgtga aatgaagcaa tttaaaattc tttcagataa atatttagag tccattacag
     4741 gttctggtgg gaacttaggc ccaggatttg gtgtgataat tccatgatgc gaaatgagtt
     4801 tcgagaaagg gtggagcaac ttcttcaaca aaaagaaata aatgaaaata gtgagttgag
     4861 tcacctgttt cgtcttgcta tacaaaattt agacagaaat gaaaaatacc aatcggtcat
     4921 ggccaatttg agtcaagggt tgtcacttta cctcatgacg catcattacc aggcacctaa
     4981 gtctgtcatt gattttggtt tatggattgc caaagctcct agccaggaaa gagggagatt
     5041 ggctttcttg cagatgcttg ctcaaaccct acagggcttt cgttaaaact gtcgaacatc
     5101 agagggaaga ctctggtgtt ttttgctgat gagactataa attttgtaaa aaatgtgata
     5161 gaatagacga cggataaaat aacggaggat agcatgcaaa atagaccaat cattattgga
     5221 gtgacaggtg gttctggtgg tggtaaaacc agtgtttcaa gagccatttt atcgcatttt
     5281 cctgatgaaa agatttccat gattgagcat gattcatact acaaggatca gtctcatttg
     5341 acctttgaag agcgtgtcaa aaccaactat gaccatcctt ttgcctttga tacagacttg
     5401 atgatcgagc agattaagga attgttggca gggcgtccgg tggacatccc gacctacgac
     5461 tatacagagc atacacggag tagcaagacc tatcgtcagg agcctcaaga tgtctttatc
     5521 gttgagggca ttttggtctt ggaggacaag cgtctgcgcg atttgatgga tatcaagatt
     5581 tttgtggata cggatgacga tgtgcgtatt attcgtcgta tcaagcgtga tatggaggag
     5641 cgtggccgta gccttgatag cgttattaac cagtacttag gtgtggtcaa accaatgtac
     5701 caccagttta tcgagtcaac taagcgttat gctgatatcg tcattcctga aggggttagc
     5761 aataccgtgg ctatcgacct gttgacgacc aagattgcaa agattttgga agaagctcga
     5821 aacagcaaat aatcacatgt ggaggccttg cctccttttt ctatttttcc ctcataatgg
     5881 tacataaatg gagattttta ggcatatttt tggtataata atacccatga aagagcaagt
     5941 aaatgaatag taggtggaga tggaaaagta tttatcggta acaactttga ccaagtatct
     6001 gaaaatgaaa ttcgataaag acccatactt ggaacgggtc tatttaactg gtcaagtttc
     6061 caactttcgt aaacgaccta ctcaccaata tttctcccta aaggatgacc atgcagttat
     6121 tcaagcgacc atctggtctg ggatttatca gaaattaggg tttgacctgg aagaaggaat
     6181 gaagatcaat gtgattgggc gtgtacaggt ctatgaacca agtggtagct actccatcat
     6241 cattgaaaaa gctgagcctg atggggttgg ggcgcttgcg attcagtttg aacaacttaa
     6301 gaaaaaattg acagaagaag gcctgtttca agaacgcttc aagcaagctc tgccccaatt
     6361 ttctaagaga attggtgtag taaccagccg tagtggagcc gttattcgag atattatcac
     6421 gaccgtcagc aggcgattcc caggtgttga catccttctt tatccgacca aggttcaagg
     6481 tgaaggggct gcggaggaaa ttgctagaaa tattgcgcgt gctaatcaac gggacgattt
     6541 ggatttgctc attattggtc gtggaggtgg ttctattgag gatctctggg cctttaacga
     6601 agaaattgtg gtacgagcta tttttgaatc tcgtttgcca gttatctcta gtgtggggca
     6661 tgagacggat gtgaccttgg cagattttgt ggcagatcga cgcgctgcaa cgccaacagc
     6721 ggcggctgaa ctggcaacac ctgtgaccaa gttggatgta ttagctcatt tgcaaaatca
     6781 ggaaaaacgg atagcaacgg cagtccgaaa tgttctatct aagaaacaag agactttgaa
     6841 aaaatgcagt cagtctgtta tctttagaca acctgagcgc ttgtatgacg gttatttgca
     6901 acgcttggac caactgcaac tgcgtttgaa acaaagtttg cgaactcgga tttctgataa
     6961 caaacaatta gttcaagcaa gaactcatca attagtacaa ttatcacctg ttaccaaaat
     7021 ccaacgctat caagaccgtt taggacagtt ggacaagctc ttaggtagcc aaatggcgtt
     7081 agtttatgac gccaaggttg ctgaggccaa gcgactttcg gaagctttgc tcatgttgga
     7141 tactagccga atcgtggcgc gtggttatgc tattgtcaaa aaagaagagt ccattgtaga
     7201 ttcggttgag agtttgaaga aaaaagacca agtaacgctt ttgatgcgag atggtcaagt
     7261 agaattagag gttaaagatg tcaaaacaaa agaaatttga ggaaaatcta gcagaactgg
     7321 aaaccattgt ccaaagtttg gaaaatggtg aaattgctct ggaagatgcg attactgcct
     7381 ttcaaaaggg catggtcttg tcaaaagagc tccaagctac gctggacaag gctgaaaaga
     7441 ccttggtcaa ggtcatgcaa gaagacggaa cagaaagtga ttttgaatga aaaagcaaga
     7501 aaaattagct cttgtcgagt cggctttgga agatttttat ggagaccagc agtttgcctc
     7561 tagtttacgg gagtctgttc tctattctat tcatgctggt ggcaagcgta ttcggccttt
     7621 tctcttgtta gaagttctgg aagccttgca ggttgccatc aaacctgctc acgcgcaggt
     7681 agctactgcc ttggagatga ttcatacagg gagcttgatt cacgatgacc ttcctgctat
     7741 ggatgatgac gattatcgaa gagggcggtt aaccaatcac aagaaattcg gtgaagctat
     7801 ggccattttg gctggagatg ccttattctt agacccatat gccttgattg cgcaggcaga
     7861 tttgccaagt cagatcaagg tggacttgat tgccaactta tcccttgctt caggtagtct
     7921 gggtatggtg gcagggcaag ttttggatat ggagggcgaa caccagcact tgtctctgga
     7981 agaacttcag actattcatg ccaataagac tgggaagtta ctagcctatc ccttccaagc
     8041 ggcagctatt atagctgaat tgtcacctga aatgcaggtg aagctgaaaa ctgtgggtga
     8101 attgattgga cttgcttttc aagtcagaga tgatgtactg gatgtgacag ctagttttga
     8161 ggaaatcggc aagacacctc aaaaggattt gcaggcagaa aaatcaacct atcctgcctt
     8221 gttgggcttg gaagagtcca ttgccttttg taaccaaacc ctggatcaag ctaatgaaaa
     8281 attagaagaa attgcccagc agcttccctt tgaaacagaa tcgattgtaa gtgtagtaga
     8341 aagtttgaga atcaatggct aaggaaagag tggatgtact agcttataaa caggggttgt
     8401 ttgaaacgag agagcaggcc aagcgaggtg tgatggctgg cctagtcgta gcagtcctta
     8461 atggagaacg gtttgacaag ccaggagaga aaattccaga tgataccgaa ttaaaactca
     8521 agggggagaa actcaagtat gtcagccgtg gtggtttgaa actggaaaag gccttgcagg
     8581 tctttgattt gtcggtggat ggcgcgacta cgattgatat cggggcctct actggaggtt
     8641 ttaccgatgt catgctacag aatagtgcca agttggtctt tgcagtcgat gttggtacca
     8701 atcagttggc ttggaaatta cgccaagacc cacgagttgt cagcatggag cagttcaatt
     8761 tccgctatgc tgaaaagact gatttcgagc aggagccgag ctttgccagt attgatgtga
     8821 gtttcatttc ccttagtctg attttgccag ccttgcaccg tgtcttggct gatcaaggtc
     8881 aggtggtagc acttgtcaaa cctcagtttg aggcaggacg tgagcagatt gggaaaaatg
     8941 gaattattcg agatgctaag gttcatcaga atgtccttga atctgtaaca gctatggcag
     9001 tagaggtagg tttttcagtc cttggcttgg acttttctcc catccaaggt ggacatggaa
     9061 atattgaatt tttagcgtat ttgaaaaaag aaaagtcagc aagcaatcag attcttgctg
     9121 agattaaaga agcagtagag agggcgcata gtcaatttaa aaatgaataa aaaagagaga
     9181 cttgaaaaaa ttagaagatt ggtgacagat tatcaaatcg gcacgcaaga agaaattgta
     9241 gaacatttga aagaagcagg tatcactgcc actcaggcga cggtatcccg agatatcaaa
     9301 gagttaggta ttgtcaaaat tcctttgaga gacaacacct atgtctacga attaccaaaa
     9361 tcaatcgtaa aaagtctgca actggctgaa gacaatatcg aatcggctga attgatggat
     9421 aagatgatca atctccaagt tattccagga aatacggctt ttgtaaaagc tcagttaatc
     9481 gatacttttg cagacaagat ttttagttgt ttgactgatg atagctcgat tttagtcatt
     9541 gccagaagtg gaagtctagc agaggaaatc tttgaacaag taaaaaattg gtaggtctat
     9601 atgttacttg aaatttcgat aaaaaacttt gccattattg aggctatttc cctcaatttt
     9661 gaaaagggga tgactgtcct gactggtgaa acgggtgcag ggaagtcgat tatcattgat
     9721 gccatgaata tgatgttggg agctcgtgcg acgacagatg ttattcgtca tggtgcacca
     9781 aaggcagaga ttgaggggct tttctcagtt gagaatagtc gtcttttaca ggaaattttt
     9841 gatgagcaag gtttagaatt aggtgatgaa attatcatcc gtcgggaaat cttgcaaaat
     9901 ggtcgtagta tcagccgtgt aaatggtcag atggttaatc tgtctgtttt gcgagctatt
     9961 gggcaacatc ttgtagatat tcatggtcag catgaccatg aggagttaat gcgtccccaa
    10021 ctgcatatcc agatgttgga tgaatttggt gatgccgctt tttgggactt gaaagaaacc
    10081 tatcaaacga gttttgatgc ctatcggaaa atgcgcaagc aggttctgga agtcaagaaa
    10141 aaccaacagg aacacaaggc acgtatcgaa atgttggaat ttcaaatggc agagattgag
    10201 gcagcaaact tgcaggctgg agaagacttg gctctcaatc aagagcgaga taaactcctc
    10261 aaccacaaaa atattgcgga tacactgacc aatgcctaca gtatgttgga caatgaagat
    10321 ttttcaagtc tggccaatgt tcgttcagcc atgaatgaca tggaaagtgt cgaagagtat
    10381 gattctgaat accgtgaaat ttcaagctct ctgtctgaga cctactatgt tttagaagac
    10441 attagcaaac gtttggaagc tatcattgag gaccttgatt ttgatggcaa tcgcctgatg
    10501 caggttgaga atcgtttgga cctccttcat actattactc gtaagtatgg tgggactgtt
    10561 gatgatgttt tgctttattt tgccaagatt acggaagaat acaatctctt gacaggcaat
    10621 aatctttcgt ctgaggacat ggaagcagag cttaagaagt tggaagtcaa tcttgtcaat
    10681 ttggcaggtc aacttgcttc tgctcgtcat aatttggctc agcaactcga agctgagatt
    10741 aaacaagaac tgcaagatct ttatatggaa aaagcccagt ttcaggttcg ttttagtaag
    10801 ggaaaattca gtcgtgaggg aaataaaatg gttgagtttt atatttcaac caaccctgga
    10861 gaagacttta aacccttggt taaggttgct tctggagggg aattatctcg tctcatgtta
    10921 gccattaagt ctgccttttc acgtaaagaa ggcaagacta gcattgtctt tgatgaggtg
    10981 gatacgggag tttcaggtcg tgttgctcaa gctattgctc agaaaattca taaaattggt
    11041 cagcatggtc aggttttggc tatctcccat ttgccacaag taattgcgat tgcagattat
    11101 caattcttta ttgagaagat tagtaatgac cattcaacgg tttcgactgt tcgtctcttg
    11161 acggtcgaag agcgagtgga ggaagttgcc aagatgttgg caggtgatga tgtgacagaa
    11221 gcagccctga cgcaagccag agaattgttg agaaacaggg agaaataaga tgacagatta
    11281 ttatgtaatt ggagatgttc acggaaaagc tgggatgctg gaagaccttc ttaaaacctg
    11341 ggatggtcag acccagttgc tctttctagg tgatttgatt gacagaggtg aggatagtca
    11401 ccgtgttctt gaaatggtca aggacttggt ggacaatcaa ggggctatct gtttgtctgg
    11461 aaaccacgag tatatgtttt tgacttggct agatgaccca gaagaaagtt atgaccatta
    11521 tcgtcgcaat ggtggagata caaccattaa ctctatccta ggtcgtccct tggatgcacc
    11581 agttgatgga gtagaagatg ccaagcgggt tgccgctgaa gcggcagact tggtcgaatt
    11641 cattcgtcaa atgccatttg tagtagagac agacaagtat atctttgttc acgcaggtat
    11701 tgatttgact ttggacgact ggcatgaaac aacagattat aaaaaagtat ggcttagaaa
    11761 accattccac ggagctgaaa atcatactgg aaaaaccatt gtcttcggtc atacaccggt
    11821 ctatggtttg ttacagcaag aacgcggtac atctgagctt tggactacag aagatggcaa
    11881 gattggaatg gatggaggag ctgtttatgg tggtgtcctt cacgggattg tctttacaga
    11941 ccaaggaatg acagaacacc actttatcga aaatgacggc tttgtcgctg aagattagta
    12001 ctcctagcag ggtatggtct tgtcaaaata tcaaaaacaa tttataataa atagataccc
    12061 tgaaaggaag agaatcatga acttagaaga attgaaaaaa cgacaggaga agatccgtaa
    12121 cttctctatt atcgcccata ttgaccacgg aaaatcaact ctagcagacc gcattttgga
    12181 aaaaacagag acggtttcaa gtcgtgaaat gcaggcccag cttttggata gcatggagct
    12241 agagcgggaa cgtggaatta ctattaagtt gaatgccatc gagttgaatt acactgcaaa
    12301 agatggggaa acttatattt tccacttgat tgacacacca gggcacgttg actttaccta
    12361 tgaagtttca cgttcgctag ctgcctgtga gggtgctatt ttggtggtcg atgcggctca
    12421 aggaattgag gctcaaactc ttgccaacgt ttatctggct ttggataatg atttggaaat
    12481 catgcctatc attaataaaa ttgacctgcc ggctgcagat ccggagcgcg tgcgtacaga
    12541 gattgaagat gtgattggtt tggatgccag tgaagcagtt ttggcttctg ccaaggctgg
    12601 tattgggatt gaagaaatcc tcgagcaaat tgtagaaaaa gtaccagcac caacgggtga
    12661 tgtgacggcg ccacttaagg ccttgatttt cgactctgtt tacgatgctt accgtggggt
    12721 tatcctccaa gtacgtgtca tggacggagt ggtcaaacct ggtgataaga ttcagctcat
    12781 gagcaatagt aagacctttg atgtggccga agtcggtatt tttacaccaa aagcggttgg
    12841 tcgtgatttc cttgcgactg gtgatgttgg ttacattgcg gcgtctatca agacggttca
    12901 ggatactcgt gtgggtgata ccgttacctt ggcaaccaat cctgcggcag aaccattaca
    12961 tggttataag cagatgaatc ctatggtctt tgcgggtctc tacccaatcg aatcaaacaa
    13021 gtacaatgac ctgcgtgaag cgcttgaaaa attgcaactg aatgatgcta gtcttcagtt
    13081 tgaaccagaa acatctcagg cacttggatt tggtttccgt tgtggatttc ttggacttct
    13141 ccatatggat gttattcagg aacgtttaga gcgtgagttc aatattgacc tcatcatgac
    13201 agctccgtct gttatttaca aagttaattt gaccgacggt gagtctatgg atgtgtctaa
    13261 cccatctgag tttccagacc caactaagat tgcgaccatt gaagagcctt atgtcaaggc
    13321 gcaaatcatg gtaccacagg agttcgtcgg agcagtaatg gagctagctc agcgtaagcg
    13381 tggggacttt gtgactatgg actatattga tgataaccgt gtcaatgtta tctatcaaat
    13441 tcctcttgct gaaattgtct ttgacttctt tgataaactt aagtcttcga cacgtggtta
    13501 tgcaagcttt gactacgaat tgtcagaata tcgcccatct aagctggtga aaatggatat
    13561 ccttctcaat ggagataagg tggatgccct cagctttatc gttcacaagg actttgccta
    13621 cgaacgtggg aaactcatcg ttgataaact caagaaaatc atccctcgcc aacaatttga
    13681 agttccaatc caagcggcta ttggacacaa gattgtcgct cgtactgata tcaaggccct
    13741 tcgtaagaac gtacttgcta aatgttatgg tggtgacgtt tctcgtaagc gtaaactcct
    13801 tgaaaaacaa aaagctggta agaaacgcat gaaatccatc ggatcagttg aagttccgca
    13861 agaagccttc ctcagcgtct tgagtatgga tgaagaataa gttatcagaa atgcctttcc
    13921 ttgttcacag gaaatttata taaaaatcaa tagtaaagca ggcttagatg gtctgctttt
    13981 ttagttttta tactcttcga aaatctcttc aaaccacgtc agcgtcgcct taccgta
//
LOCUS       DAVAGB010000048        13201 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVAGB010000048 DAVAGB010000000
VERSION     DAVAGB010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13201
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.049"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            113..586
                     /gene="tnpA"
                     /locus_tag="VQO19_001719"
     CDS             113..586
                     /gene="tnpA"
                     /locus_tag="VQO19_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISSpn6 family
                     transposase"
                     /protein_id="HET1349947.1"
                     /translation="MREDNQSLSHTTWNCKYHIVFAPKYRRQIIYGRYKASIGRIIRD
                     LCERKGVIIHEANACSDHIHMLISIPPKLSVLSFMGYLKGKSSLMIFDKHANLKYKYG
                     NRKFWCRGYYVDTVGRNQKVIAEYIQNQLQEDRVADQLTLFESVDPFTGEINKRK"
     gene            complement(839..926)
                     /locus_tag="VQO19_001720"
     tRNA            complement(839..926)
                     /locus_tag="VQO19_001720"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(890..892),aa:Ser,seq:gga)
     gene            1089..1829
                     /locus_tag="VQO19_001721"
     CDS             1089..1829
                     /locus_tag="VQO19_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET1349948.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPYSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGINGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            1826..2737
                     /gene="pfkB"
                     /locus_tag="VQO19_001722"
     CDS             1826..2737
                     /gene="pfkB"
                     /locus_tag="VQO19_001722"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HET1349949.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDVVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            2734..4686
                     /locus_tag="VQO19_001723"
     CDS             2734..4686
                     /locus_tag="VQO19_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET1349950.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGSSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            4850..7075
                     /locus_tag="VQO19_001724"
     CDS             4850..7075
                     /locus_tag="VQO19_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET1349951.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(7120..7548)
                     /locus_tag="VQO19_001725"
     CDS             complement(7120..7548)
                     /locus_tag="VQO19_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349952.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            7686..8828
                     /locus_tag="VQO19_001726"
     CDS             7686..8828
                     /locus_tag="VQO19_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET1349953.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWLIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRHDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     NYPDIFVFSDEENFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            8837..10051
                     /gene="thiI"
                     /locus_tag="VQO19_001727"
     CDS             8837..10051
                     /gene="thiI"
                     /locus_tag="VQO19_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HET1349954.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            10186..11010
                     /locus_tag="VQO19_001728"
     CDS             10186..11010
                     /locus_tag="VQO19_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET1349955.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPGQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYFECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            11032..11771
                     /locus_tag="VQO19_001729"
                     /pseudo
     CDS             11032..11771
                     /locus_tag="VQO19_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            11784..12950
                     /locus_tag="VQO19_001730"
     CDS             11784..12950
                     /locus_tag="VQO19_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET1349956.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLKTEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFLASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
BASE COUNT         3850 a         2540 c         2997 g         3814 t
ORIGIN      
        1 ctatgctagt ggttccatag agcttttagc gtggtaacaa aaagaacctc ctaaaatgat
       61 aagatagaag tggtttctcc gccactacaa catatcatac aggaggtacc tcatgagaga
      121 ggataatcaa agtttatcac ataccacatg gaattgtaaa tatcatattg tttttgcacc
      181 caaatatcgt cgtcaaatca tttatggcag atacaaagct agtatcggaa gaatcatacg
      241 tgacttatgt gagcgtaagg gtgtaataat ccatgaagcg aatgcttgtt cagaccatat
      301 tcacatgctt atcagtattc ctccgaaact tagtgttttg tcctttatgg gctatttaaa
      361 gggcaagagc agtttgatga tttttgataa gcatgcgaat ttaaaataca aatatggcaa
      421 tcgcaagttt tggtgtagag gctattatgt agatacggta ggccgtaatc agaaagtgat
      481 agctgaatat attcagaatc aattacaaga agacagagta gcagaccagc tcacgttatt
      541 cgagtcagta gatccgttta ctggcgaaat aaataagagg aagtaactaa ggtgctttag
      601 cacctgctcg ggaaagtggt gcgcgaggaa gctatttcgg tgggcctttg gccctggccg
      661 gtagaagcgg cttatagccg cagaacaaac caccagttca cactggtggt tttgattatc
      721 tttggtattc ctttgcattc ttttgctaaa aagggagtca caaacagacc ctattttaaa
      781 aaaaggatag aaaaaaggat acaacatttg tcgcatccta aaaataatct tttttcgacg
      841 gaagacatgg gattcgaacc cacgcacgct attacacgcc taccgcgttt ccaacacggc
      901 ctcttaagcc tcttgagtaa tcttccaata cttactcaaa tagtctacca taaaggctct
      961 tatcttgcaa taaaaattct agaaataaga aaaaatgata gattttgaaa gaaaatgata
     1021 aaaaatgctt gacttcgaaa gaaagtatga tagaatgaat agtgtaaacg ataacaggag
     1081 gtgattcagt gttaaaaaca gaacgtaaac aactaatttt agaggagtta aatcaacatc
     1141 atgtagtttc tctagaaaaa ttagttagtt tgctagaaac gtcagaatca acggttcgaa
     1201 gagacttgga tgagttggaa gcggaaaaca agcttcgtcg tgtgcatggt ggagcagaac
     1261 tcccctactc cttacaggaa gaagaaacca ttcaagaaaa atctgtcaaa aaccttcaag
     1321 aaaagaaatt gctggctcag aaagcagcct ctctcattaa agaaaaagat gtcatcttta
     1381 tcgatgctgg aacaacaact gcttttttga ttcatgaatt ggtcaataag aatgttacag
     1441 ttgtgaccaa ctccattcac catgccgctc agttggttga aaagcagatt ccaactgtca
     1501 tggttggagg aaacgtcaag acggcgacag atgctagtat cgggggcgtt gctcttaacc
     1561 agattaacca attgcacttt gaccgtgcct ttatcggaat aaatggtgtt gacgatggct
     1621 attatacgac tcctgatatg gaggagggag ctgtgaaaag agctattttg gagaatgcca
     1681 agcagaccta cgtcttggtg gattcgtcaa aaattggaca aacttgcttt gccaaggtag
     1741 ccccactcaa acgcgctatc gttatcacta gtcaagggca tgagctcttg caggttatta
     1801 aggagaaaac ggaggtaata gaagtatgat ttatacagtc acactcaatc catccattga
     1861 ctatatcgtt cgtttggacc aagtcaaagt tggtagtgtc aatcgtatgg acagtgatga
     1921 taagtttgct ggtgggaaag gaatcaatgt cagccgtgtc ttgaaacgtt tgaatatacc
     1981 aaatacagcg acgggattta tcggtggctt tactggtaaa tttatcacag atactttagc
     2041 agaggaagaa atcgagacac gttttgtcca ggtggcagaa gatactcgta tcaatgttaa
     2101 aatcaaagca gaccaagaaa cagaaatcaa cggaacgggt ccaactgttg aatcggttca
     2161 gctagaagaa ttgaaagcta ttttatctag tctgacagca gaagatacag ttgtctttgc
     2221 aggttcaagt gctaaaaatc taggcaatgt tatctataag gatttgattt ccttgacgcg
     2281 ccagactggt gcgcaagtgg tctgtgactt tgaaggacag accttaattg atagtttgga
     2341 ctaccagcct cttcttgtaa aaccaaacaa tcatgaactt ggagcgattt ttggggttaa
     2401 actcgaaagt ttagatgaaa ttgagaaata cgctcgtgag ttactggcta agggtgctca
     2461 aaatgttatt atctctatgg ctggtgatgg tgcccttctt gtcacatctg agggagctta
     2521 cttcgctaaa ccaatcaaag gaacagtcaa aaattcagtt ggagctggtg attctatggt
     2581 tgctggattc acaggtgaat ttgtcaaatc aaaagacgta gtagaagcct tcaaatgggg
     2641 agtggcttgc ggaacggcaa ctaccttctc agatgacttg gcaacggcgg aatttattaa
     2701 agaaacatat ggaaaagttg aggtagaaaa acgatgaaaa ttcaagacct attgagaaaa
     2761 gatgtcatgt tgctagattt gcaggcaact gaaaaaacag ctgtcatcga cgagatgatt
     2821 aaaaatttga cagaccacgg ttatgtaaca gattttgaaa catttaaaga aggaattttg
     2881 gcgcgtgaag ctttgacttc tactggtttg ggtgatggaa tcgcaatgcc tcacagcaaa
     2941 aacgctgctg tcaaagaagc gacagttcta tttgctaagt caaataaggg tgttgactac
     3001 gagagcttgg atggacaagc aactgacctc ttcttcatga ttgcagctcc agaaggtgcc
     3061 aatgatactc acttggcagc cttggcagaa ttgtctcaat acttgatgaa agacggtttt
     3121 gcagacaaac ttcgtcaagc aacatctgca gaccaagtta tcgaactttt tgaccaagct
     3181 tcagaaaaaa ctgaggaact tgttcaagca cctgctaatg actctggtga ctttatcgta
     3241 gctgttacag cttgtacaac aggtattgcc cacacttaca tggcccaaga agcccttcaa
     3301 aaagtagctg ctgaaatggg ggttggtatc aaggtcgaaa ccaacggtgc tagcggtgtt
     3361 ggaaatcaac taactgcaga agatatccgt aaggctaaag ctattatcat tgcagcagac
     3421 aaggccgttg aaatggatcg atttgatgga aaaccattga tcaatcgtcc agttgctgac
     3481 ggtatccgta agacagaaga gctaattaac ttggctcttt caggagatac tgaagtctac
     3541 cgtgccgcta atggtgccaa agctgcaaca gcctctaacg aaaaacaaag ccttggtggt
     3601 gccttgtaca aacacttgat gagtggtgta tctcaaatgt taccattcgt tatcggtggt
     3661 ggtatcatga ttgcccttgc cttcttgatt gacggtgctt tgggtgttcc aaatgaaaac
     3721 cttggcaatc ttggttctta ccatgagtta gcttctatgt tcatgaaaat tggtggagct
     3781 gcctttggtt tgatgcttcc agtctttgcg ggttatgttg cctactctat tgctgaaaaa
     3841 ccgggtttgg tagcaggttt cgtggctggt gctattgcca aagaaggttt tgcctttggt
     3901 aaaattcctt atgccgcagg tggtgaagca acttcaactc ttgcaggtgt ctcatctggt
     3961 ttcctaggtg cccttgttgg tggatttatc gcaggtgcct tggttcttgc catcaagaaa
     4021 tacgttaaag ttcctcgttc actcgaaggt gctaaatcaa tccttctatt gccacttctt
     4081 ggaacaatct tgacaggatt tgttatgcta gctgtgaata tcccaatggc tgcaatcaac
     4141 actgctatga atgacttcct aggcggtctt ggaggaagtt cagctgtcct tcttggtatc
     4201 gtccttggtg gaatgatggc tgttgacatg ggtggaccag ttaataaagc agcttatgtc
     4261 tttggtacag gtacgcttgc agcaactgtt tcttcaggtg gttctgtagc catggcagca
     4321 gttatggctg gaggaatggt gccaccactt gcaatctttg tcgcaactct tcttttcaaa
     4381 gataaattta ctaaggaaga acgtaactct ggtttgacaa acatcatcat gggtttgtca
     4441 tttatcactg agggagcgat tccatttggt gccgctgacc cagctcgtgc gattccaagc
     4501 ttcatccttg gttcagcagt agcaggtgga ctcgttggtc ttactggtat caaactcatg
     4561 gcgccacacg gaggaatctt cgttatcgcc cttacttcaa atgctctcct ttacctcgtt
     4621 tctgtcttgg taggagcaat cgtaagtggt gtggtttatg gttacctacg caaaccacaa
     4681 gcataaaaaa tagaaaaatg aaaagattgg accgtttggt gcagtctttt tctcttcccg
     4741 aaatgcctgt gaaatatggt ataatagaag aatggcaaac aagaatacaa gtacaacaag
     4801 acggagaccg tctaaagcag aactggaaag aaaagaagcg attcaacgaa tgttgatttc
     4861 gttaggaatt gcgattttat tgattttcgc agccttcaaa ttaggggctg caggtataac
     4921 cctttataat ttaattcgct tgctagtggg tagcctagct tatctggcga tattcggcct
     4981 attaatctat ctcttctttt tcaagtggat acgaaaacag gaaggactct tatctggctt
     5041 tttcaccata tttgctggct tactcttgat ttttgaggcc tacttggttt ggaaatatgg
     5101 tttggacaag tccgttctaa aagggaccat ggctcaggtt gtgacagatc tgactggttt
     5161 tcgaacgact agctttgctg gagggggctt gatcggggtc gctctttata ttccaacagc
     5221 ctttctcttt tcaaatattg gaacttactt tattggttct atcttgattt tagtgggttc
     5281 tctcctagtc agcccttggt ctgtttacga tattgctgaa tttttcagta gaggctttgc
     5341 caaatggtgg gaagggcacg agcgtcgaaa agaggaacgc tttgtcaaac aagaagaaaa
     5401 agctcgccaa aaggctgaga aagaggctag attagaacaa gaagagactg aaaaagcctt
     5461 actcgatttg cctcctgttg atatggaaac gggtgaaatt ctgacagagg aagctgttca
     5521 aaatcttcca cctattccag aagaaaagtg ggtggaacca gaaatcatcc tgcctcaagc
     5581 tgaacttaaa ttccctgaac aggaagatga ctcagatgac gaagatgttc aggtcgattt
     5641 ttcagccaaa gaagcccttg aatacaaact tccaagctta caactctttg caccagataa
     5701 accaaaagat cagtctaaag agaagaaaat tgtcagagaa aatatcaaaa tcttagaagc
     5761 aacctttgct agctttggta ttaaggtaac agttgaacgg gccgaaattg ggccatcagt
     5821 gaccaagtat gaagtcaagc cggctgttgg tgtaagggtc aaccgcattt ccaatctatc
     5881 agatgacctc gctctagcct tggctgccaa agatgtccgg attgaagcac caatccctgg
     5941 gaaatcccta atcggaattg aagtgcccaa ctccgatatt gccactgtat ctttccgaga
     6001 actatgggaa caatcgcaaa cgaaagcaga aaatttcttg gaaattcctt tagggaaggc
     6061 tgttaatgga accgcaagag cttttgacct ttctaaaatg ccccacttgc tagttgcagg
     6121 ttcaacgggt tcagggaagt cagtagcagt taacggcatt attgctagca ttctcatgaa
     6181 ggcgagacca gatcaagtta aatttatgat ggtcgatccc aagatggttg agttatctgt
     6241 ttacaatgat attccccacc tcttgattcc agtcgtgacc aatccacgca aagccagcaa
     6301 ggctctgcaa aaggttgtgg atgaaatgga aaaccgttat gaactctttg ccaaggtggg
     6361 agttcggaat attgcaggtt ttaatgccaa ggtagaagag ttcaattccc agtctgagta
     6421 caagcaaatt ccgctaccat tcattgtcgt gattgtggat gagttggctg acctcatgat
     6481 ggtggccagc aaggaagtgg aagatgctat catccgtctt gggcagaagg cgcgtgctgc
     6541 aggtatccac atgattcttg caactcagcg tccatctgtt gatgtcatct ctggtttgat
     6601 taaggccaat gttccatctc gtgtagcatt tgcggtttca tcaggaacag actcccgtac
     6661 gattttggat gaaaatggag cagaaaaact tcttggtcga ggagacatgc tctttaaacc
     6721 gattgatgaa aatcatccag ttcgtctcca aggctccttt atctcggatg acgatgttga
     6781 gcgcattgtg aacttcatca agactcaggc agatgcagac tacgatgaga gttttgatcc
     6841 aggtgaggtt tctgaaaatg aaggagaatt ttcggatgga gatgctggtg gtgatccgct
     6901 ttttgaagaa gctaagtctt tggttatcga aacacagaaa gccagtgcgt ctatgattca
     6961 gcgtcgttta tcagttggat ttaaccgtgc gacccgtctc atggaagaac tggagatagc
     7021 aggtgtcatc ggtccagctg aaggtaccaa acctcgaaaa gtgttacaac aataaaaaaa
     7081 tagcttcttt ccaagtttgg agggaagcta ttttagtggc tattgattgc ttttattttc
     7141 tgaagttggc gcattggact gtttttcgtt ttcagtagca ggtttacttg aagcaggagt
     7201 agaagagtcc tgagttgctg ttttctgatc ttcttttttc tcttccttga cgctagattt
     7261 tggtgtttcc tcttgctgtg ttttttcttg actagtgtta gtctctttag ttggactggt
     7321 gttttcctta ggggattcct tttggatttc tttgacaatg gttgtcgtct ggcttgtcgt
     7381 aggttctttt ttaatatttt tgttattatc caaggcgttc ataatcgtga tacttgcggt
     7441 aatcaagcca aggatactag cgattgtagc aacggttttt tgaaagactg taaagccttt
     7501 tttgatgtgt tctgtttttg gttttgaagt tctacgatag ttagacatac attctctcct
     7561 ttgattatga tttattatac tctgtttctt taaaaaaatc ttaaaaaaag agaaatttcc
     7621 ctttcttgtc gcaagctccg tttcatgata caatagagga agtgatttta gaaagcgtga
     7681 gaaacatgat ttactttgat aattcagcga cgaccaagcc ttatcctgaa gcccttgaaa
     7741 cctatatgca ggtcgcttca aaaattttag gaaacccatc tagtctccat cgtttgggag
     7801 accaagcaac acgaatctta gatgcttctc gccaacagat tgcagattta atcggtaaga
     7861 aaagcgatga aatcttcttt acctcgggtg gaacagaagg ggataactgg cttatcaagg
     7921 gtgtggcctt tgaaaaagct cagtttggca agcacatcat tgtttcagcc attgaacatc
     7981 cagcagtcaa agagtcagcc ctctggttga aaagtcaagg atttgaagtg gattttgctc
     8041 cagttgataa gaaaggcttg gtcgatgttg aggcgttagc aggtttgata cggcatgata
     8101 caatcctcgt ttccatcatg gctgtgaaca atgaaatcgg ctctatccaa cctattgagg
     8161 ctatttcaga attcttggca gacaagccga ctatttcctt ccacgttgat gcggttcagg
     8221 cgcttgccaa aattccgact gaaaagtatc tgacagaacg ggtggattgc gcgactttct
     8281 ctagtcacaa gttccacggg gttcgaggtg ttggctttgt ctatatcaaa tctggcaaga
     8341 agattacacc tcttcttaca ggtggtggcc aggagcgaga ttatcgttcg acaactgaaa
     8401 atgtggcagg gattgcagcg acagccaagg ccctccgttt gtctatggaa aagctagata
     8461 tctttaggag caagactggg cagatgaagg cagtgattcg ccaagctctt ctgaactatc
     8521 cggatatttt tgtcttttca gatgaggaaa actttgcacc tcatattctg acttttggaa
     8581 tcaaaggtgt tcgaggtgaa gtcatcgttc acgcctttga agactatgat attttcatct
     8641 caacaacctc agcttgttca tctaaggcag gaaaaccagc cggtaccttg attgccatgg
     8701 gagtggacaa agataaggcc aagtcagctg tgcgtcttag cctagacttg gaaaatgata
     8761 tgagtcaggt cgagcagttt ttgaccaagt taaaattgat ttacaatcaa actagaaaag
     8821 taagatagga gcattcatgc agtattcaga aattatgatt cgctacggag agttgtcaac
     8881 caagggtaaa aaccgtatgc gtttcatcaa taaacttcgt aataatattt cggacgtttt
     8941 gtctatctat acccaagtta aggtaacagc agatcgcgac cgtgcccacg cttacctcaa
     9001 tggagctgat tacacagcag ttgcagaatc tctcaaacaa gtttttggaa ttcaaaactt
     9061 ttctcctgtt tataaggttg aaaaatctgt agaagttttg aagtcttctg tccaagagat
     9121 tatgcgggac atctacaagg aaggtatgac ctttaagatt tctagcaagc gtagcgacca
     9181 caactttgaa cttgatagtc gtgaactcaa ccaaacactt ggaggggctg tattcgaagc
     9241 cattccaaat gtgcaagttc aaatgaaaag tcctgacatc aatcttcagg tggagattcg
     9301 tgaagaagca gcctatcttt cttatgaaac cattcgtggg gctggtggtt tgccagttgg
     9361 aacttcaggt aaagggatgc tcatgttgtc aggagggatt gactcacctg tagcaggtta
     9421 tcttgctctt aagcgtgggg tggatatcga ggcagttcac tttgctagtc caccatatac
     9481 tagtcctggt gccctcaaga aagcgcagga cttgacccgt aaattgacca agtttggcgg
     9541 aaatatccag tttatagagg tgcctttcac agagattcaa gaggaaatca aagccaaagc
     9601 gccagaagct tatttgatga ctctaactcg tcgctttatg atgcggatta ctgaccgtat
     9661 tcgtgaggta cgaaatggtt tggttatcat caatggggaa agtctaggtc aagtagccag
     9721 ccaaaccctt gaaagtatga aggctatcaa tgctgttacc aacactccca tcattcgtcc
     9781 tgtggttacc atggacaagt tggaaatcat tgacatcgcc caggaaatcg atacctttga
     9841 catttcaatc caaccgtttg aagactgttg taccattttt gcaccagatc gtccaaaaac
     9901 aaatcctaaa attaagaatg cggagcagta cgaagcgcgt atggatgttg aaggcttggt
     9961 tgagcgagca gtggctggaa tcatgattac tgaaatcaca cctcaagccg aaaaagatga
    10021 agttgatgac ttgattgaca atctgctcta attcagaaaa tccaaaagaa tagcgaaaat
    10081 cagtaaaaaa agttagtttt ttctctaaaa acaggtaaaa aactaacttt ttttattttt
    10141 atgatataat gatataaaat tttgaatata gagagttttc tgacaatgaa tcaatcctac
    10201 ttttatctaa aaatgaaaga acacaaactc aaggttcctt atacaggtaa ggagcgccgt
    10261 gtacgtattc ttcttcctaa agattatgag aaagatacag accgttccta tcctgttgta
    10321 tactttcatg acgggcaaaa tgtttttaat agcaaagagt ctttcattgg acattcatgg
    10381 aagattatcc cagctatcaa acgaaatccg gatatcagtc gcatgattgt cgttgctatt
    10441 gacaatgatg gtatggggcg gatgaatgag tatgcggctt ggaagttcca agaatctcct
    10501 atcccagggc agcagtttgg tggtaagggt gtggagtatg ctgagtttgt catggaggtg
    10561 gtcaagcctt ttatcgatga gacctatcgt acaaaagcag actgccagca tacggctatg
    10621 attggttcct cactaggagg caatattacc cagtttatcg gtttggaata ccaagaccaa
    10681 attggttgct tgggcgtttt ttcatctgca aactggctcc accaagaagc ctttaaccgc
    10741 tatttcgagt gccagaaact atcgcctgac cagcgcatct tcatctatgt aggaacagaa
    10801 gaagcagatg atacagacaa gaccttgatg gatggcaata tcaaacaagc ctatatcgac
    10861 tcgtcgcttt gctattacca tgatttgata gcagggggag tacatctgga taatcttgtg
    10921 ctaaaagttc agtctggtgc catccatagt gaaatccctt ggtcagaaaa tctaccagat
    10981 tgtctgagat tttttgcaga aaaatggtaa gttaagaaag gaaaaaacga aatgcatatt
    11041 gaacatctta gccactggag tggtcatctt aaccgtgaaa tgtaccttaa ccgttatgga
    11101 catggtggga ttccagttgt ggtctttgct tcatcaggtg gtagtcacaa cgaatactat
    11161 gattttggca tgattgatgc ctgtgcttcc tttatcgagg aaggccttgt ccagttcttt
    11221 accctatcta gtttggatag tgagagctgg ttggctactt ggaaaaatgc tcatgaccaa
    11281 gcggaaatgc accgtgccta cgaacgttat gtgattgagg aggccattct tttatcaagc
    11341 acaagacagg ttggtttgat ggcatgatga cgacaggttg ctctatggga gcctatcatg
    11401 cactcaattt cttcctccag catccagatg tctttaccaa agtgattgct ctcagtggtg
    11461 tttacgacgc acgtttcttt gtcggtgatt actacaacga tgatgctatt taccaaaact
    11521 cgccagtaga ttatatttgg aaccaaaacg acggctggtt tattgaccgt taccgtcagg
    11581 cagagattgt gctgtgtacg gggcttggag cctgggaaca agatggtttg ccatcctttt
    11641 acaagctcaa agaagccttt gacaagaaac aaattccagc ctggtttgct gaatggggac
    11701 atgatgtcgc ccatgactgg gaatggtggc gtaaacaaat gccttatttc ctcggtaatc
    11761 tctatttata aaaggagtta cctatgaatt accttgttat ttctccctac tatccacaaa
    11821 actttcaaca gtttaccatc gaactagcta ataaaggcat cacagtcttg ggaattggtc
    11881 aagagtctta cgagcaattg gatgagccct tgcgcaatag cttgaccgag tattttcgtg
    11941 ttgataatct tgagaacata gatgaagtca aacgtgcagt tgcttttctc ttttataaac
    12001 atggtccaat tgaccgcatc gagtctcaca atgaatactg gcttgagcta gacgcaacac
    12061 tcagagaaca attcaatgtt tttggtgcca aaccagagga tctcaaaaag acgaaatata
    12121 agtctgaaat gaagaaactt ttcaaaaaag caggtgttcc tgtggtacct ggagctgtta
    12181 tcaagacgga agcagatgtt gatcaagcag tgaaagaaat cggtcttcca atgattgcca
    12241 aacctgataa tggagtggga gcagccgcaa cctttaaact taagacagaa gacgatatca
    12301 atcacttcaa gcaagaatgg gaccattcaa ccctttattt ctttgaaaaa tttgtcactt
    12361 ccagcgaaat ctgtaccttt gacgggctcg tggacaagga tggaaagatt gtcttctcaa
    12421 caacctttga ctacgcctat acaccgcttg acctcatgat ttataagatg gacaattctt
    12481 attatgtgct caaggatatg gatcctaaac tgcgcaagta tggggaagca attgtcaaag
    12541 aatttggtat gaaagaacgg tttttccata ttgagttctt ccgtgagggg gacgattata
    12601 ttaccatcga gtacaataac cgccctgcag gtggttttac cattgatgtt tataactttg
    12661 ctcattcctt ggacctttat cgtggctatg cagctattgt cgcaggagag gagttcctgg
    12721 cgtcagactt tgaaactcag tattgtttgg ctacttctcg ccgtgcaaat gctcactatg
    12781 tttattcaga agaggatttg cttgccaaat atagccagca gttcaaggtt aaaaaagtca
    12841 tgccagctgc cttcgcggaa cttcaaggag attacctgta tatgctgaca actccgagtc
    12901 gacaagaaat ggatcagatg attgctgatt tcggacaacg tcaagaataa gaactatcgg
    12961 attaaggaaa ttcactccct taatcctttt gttttgtctg gtaaaaaata agagcatcct
    13021 aacaaggtag ctatcataaa acttgttcga taactatttg aagcaggatt aggtggctag
    13081 aaattgaatt ttaacatttc aatttagtca tagtattgtg ttttcgtatc cttaaatcag
    13141 ctaaaaggat ccatgacgac acctatacga tatagttttc aggataccaa accagtctat
    13201 t
//
LOCUS       DAVAGB010000049        12668 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVAGB010000049 DAVAGB010000000
VERSION     DAVAGB010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12668
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.050"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            1..468
                     /locus_tag="VQO19_001731"
                     /pseudo
     CDS             1..468
                     /locus_tag="VQO19_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(670..2928)
                     /locus_tag="VQO19_001732"
     CDS             complement(670..2928)
                     /locus_tag="VQO19_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET1349957.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(3157..3387)
                     /locus_tag="VQO19_001733"
     CDS             complement(3157..3387)
                     /locus_tag="VQO19_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HET1349958.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3577..4260
                     /locus_tag="VQO19_001734"
     CDS             3577..4260
                     /locus_tag="VQO19_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET1349959.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            4260..4994
                     /locus_tag="VQO19_001735"
     CDS             4260..4994
                     /locus_tag="VQO19_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET1349960.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGISLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLRKVL"
     gene            5148..6005
                     /locus_tag="VQO19_001736"
     CDS             5148..6005
                     /locus_tag="VQO19_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HET1349961.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKIAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDSAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMVPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLTSHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            6147..7019
                     /locus_tag="VQO19_001737"
     CDS             6147..7019
                     /locus_tag="VQO19_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HET1349962.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            7301..7984
                     /gene="rpiA"
                     /locus_tag="VQO19_001738"
     CDS             7301..7984
                     /gene="rpiA"
                     /locus_tag="VQO19_001738"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HET1349963.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTSKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKIVATPSKEYIWVVDESKLVDKLGAFKLPVEVVQYGAEQIFRRFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIEDPIVFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QILTSRKEK"
     gene            7998..9209
                     /locus_tag="VQO19_001739"
     CDS             7998..9209
                     /locus_tag="VQO19_001739"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HET1349964.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFAPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGVIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            9211..9753
                     /locus_tag="VQO19_001740"
     CDS             9211..9753
                     /locus_tag="VQO19_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET1349965.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYQKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9769..10578
                     /locus_tag="VQO19_001741"
     CDS             9769..10578
                     /locus_tag="VQO19_001741"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET1349966.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIRFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            11054..11449
                     /locus_tag="VQO19_001742"
     CDS             11054..11449
                     /locus_tag="VQO19_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HET1349967.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            11459..12034
                     /locus_tag="VQO19_001743"
     CDS             11459..12034
                     /locus_tag="VQO19_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET1349968.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPRSSSQPSAEPME
                     NIALGKQVTQSSTVFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            12059..12571
                     /locus_tag="VQO19_001744"
     CDS             12059..12571
                     /locus_tag="VQO19_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HET1349969.1"
                     /translation="MSAQITINHKKVRYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGC
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
BASE COUNT         3748 a         2319 c         2854 g         3747 t
ORIGIN      
        1 aagcacctag cacctgttta gattgacgaa acaggattcg atacttattt ttatcgagaa
       61 tatggtcgct cattaaaagg tcagttaata agaggtaaag tatctggaag aagatatcag
      121 aggatttctt tggttgcagg tctaacaaat ggtgagttaa tcgctccaat gacttacgaa
      181 gagatgatga cgagcgactt ttttgaagct tggtttcaga agtttttctt accaacatta
      241 accacaccat cggttattat tatggataat gtaagattcc atagaatggg gaagctagaa
      301 cttttatgcg aagagtttgg gcataaactt ttacctcttc ctccctactc gcctgagtac
      361 aatcctattg agaaaacatg ggctcatatc aaaaagcacc tcaaaaaggt attaccaagt
      421 tgcaatacct tttacgaggc tcttttgtcc tgttcttgtt tcaattgact atagcagatt
      481 gaaatgagaa caaatcgatt gggaaagtaa aattaatttc tataaatgtt ttagcaattg
      541 tttcgtacta tttcagattc agtctactat atatcataat ggacaaaggg caagctgtca
      601 agaaattaca gttattttag taaaaaaaga agcagaaaaa tttcattttc tactcctttt
      661 ctataggatt tatttttctt tttcagaact tttaacttca gcttttttgg cagatttaat
      721 ctgaatgttt cccttgctag tcataactgc tttgagatct ttttcgcttg gattttcaag
      781 gtagtagtca gtgattgtgt cctcaatata gtcttgaata gtccgacgaa gtgggcgtgc
      841 tcccattttt ggatcataac ctaggtcaac caacttttcc ttgaccttat cagttacatc
      901 caaacgaatg ttgttgctag agaggcgctt gttaacatct gctagcatga gctcgacaat
      961 ctgaaggagg ttatccttgc tgagagcctt aaattcgata atgccatcaa aacggttcat
     1021 aaactctggg ctaaagaagt taccgagttc accgaggaca gaattggtac gtccttctct
     1081 agcagcacca aatccaacgc tagcttcggt ctttcctgta cctgcatttg aggtcatgat
     1141 aatgatggca tccttgaagc taacggtgcg tccttgcccg tctgtcaaac gaccatcgtc
     1201 caagacttga agaaacatgt gcataacatc tgggtgagct ttttccactt catcgagaag
     1261 gatgagagaa tatggattgt ggcgaacttt ttcagttaat tgaccagcct catcatagcc
     1321 aacataacct ggaggggcgc cgaccaactt agccacacta tgtttttcca tgtattcact
     1381 catatcaaag cgaatcatac tatcagcaga accaaaaagt tcgatagcca gttgtttgga
     1441 aagttctgtc ttaccgacac cagttggccc aacgaagagg aagcttccga ttgggcggtt
     1501 aggggtacca agtccgacac gattacggcg aatagccttg gcaatcttat cgactgcatc
     1561 atcttggcca ataacatgag acttgagatc ttcggctaga tggatgagtt gagattgttc
     1621 tttctctttc aaatcaccaa cagggatatt ggttttctgc tcgataatgt gctcaatagt
     1681 tttctcgctg atgataggag tatcctggtc tgtgatcttt ttcttttgca tttccttata
     1741 cttggcaatc tggtcgcgga agtaggccgc cttctcaaaa tcttcttctc gtgtagcttg
     1801 agacttgaga ttttcagcct caatcaagcg ctgatcaatt actttaggat ccacaaaatt
     1861 caaggtcaag ttcatcttag aaccagcttc atctaggagg tcaatggcct tgtcaggcaa
     1921 gaagcgatct tggatgtagc gattggaaag agttgcagct gcttcaatcg cagcatcggt
     1981 atattgaacg tggtggtaat cttcgtattt cttttgaatc cctttgagaa tagtgattgt
     2041 ttcatccacc gttggttcat cgactttaac aggctgcata cgacgctcga gggcagcatc
     2101 cttttcaatg atacggtatt cattgagggt agtagcaccg actagttgca gttctccacg
     2161 agcaagggct ggcttgagga tatttcctgc gtccatatta ccatcactcg cagaaccagc
     2221 accaacaatt tcatggattt catcgataaa gaggatgatg tcttcacgtt tgcgaatttc
     2281 ttccatgagt ttttgcatgc gttcttcaaa ttgtcctcga atccccgttc cttgaactaa
     2341 gctaaccaca tccagacgga tgacttgttt accttggagt ttatgtggca catcgccatc
     2401 gacaattttc tgagctagac cttcgacaac ggccgttttt ccgacaccag gttcaccgat
     2461 aaggacagga ttattcttgg ttctacgatt gagaatctcg atgacacgga taatctcatc
     2521 gtcgcgccca ataacggggt caatgtctcc acgacgggca atttcagtta cattaatacc
     2581 aaattcttcc agcaggcctt tttcttggct aggtggcgga gtttgagcag atccacgatt
     2641 ttgggaacca taaccgccgt ttccaccgta acctccacct gattgggttg ggggaatagg
     2701 aggagtattg ctagaaggtc tgaaattgtt tagatcattg aagaaatcac caaagggatc
     2761 gaagtcacga ttgttcagat ccgtcatacc tttgaagagg ctattgttag gatctgtttt
     2821 gataatctta tagcagtttt gacagaggtc aatttgtttt tgttttccat tgagattggt
     2881 gtaaagatga attgttgagt cgttaatttt acagttttga caaagcatac atctacctca
     2941 tttctttctt tagcctgact tgtttaaagg tcaaaaatag tcaaattcta tactctcatt
     3001 ataacaggat tggggtgtaa agcaagtaaa aagattgaag ctttgagaag ttgttacaat
     3061 gaaaattttt gtgaatttgg actataaaaa aatcctattt gtgagacaaa aaggatttta
     3121 cttagacatg cagggacaat cccagcttgt tttagattag tagagaagtt cgtaaatttc
     3181 cattgcgatt aagtcaatgc tatcaaacgt atacgtttcg cgatcttcta cgtcacgaag
     3241 ggtaaagatt gggccgtttt cttcgtcgtg gctgtacgca acttctgcaa caacaactcc
     3301 ttcgcgttca aaattacgtt ttaaatttcc gccatcgttt gccattgctt caaggcggtt
     3361 gatgattcta accaaatgtg attccatttt gattctcctt catttcttat cgttactatt
     3421 ttaccataaa ggaggccaac ttgactagaa aaaactaaga tttctcgcta attctgctag
     3481 tttaaagatt tttaaataaa ttggataaaa aatttaaatt ttaattcaaa acatgttata
     3541 atcatacagt attctatttt agaaagcagt gtgactatga atttttcttt tttacctaag
     3601 tatttacctt attttaacta tggggctgtt gtgacgattc ttatttctat ctgtgttatc
     3661 tttttgggaa ctattttggg tgttgtcttg gcttttgggc aacgttcaaa gtttaaaccg
     3721 cttgtttggt tggccaactt gtacgtttgg attttccgtg ggacaccgat gatggttcaa
     3781 attatgattg cctttgctct tatgcatatc aatgctccga ctattcagat tggaatttta
     3841 ggtgttgatt tttcgcgtct gattccaggg attttgatta tctctatgaa tagtggtgct
     3901 tatgtttcgg agactgttcg tgccggaatc aatgcggttc caaaaggtca gctagaggcg
     3961 gcttattcgc tagggattcg tcctaaaaat gcgatgcgtt atgtgatttt gccacaagca
     4021 gtcaaaaata tcttgccagc attggggaac gaatttatca ccattatcaa ggacagctcc
     4081 ctcttatcag ctattggggt catggagttg tggaatgggg ctacaacagt ttctacaaca
     4141 acctatctac ctttaacacc acttttattt gcagcatttt actacttgat tatgacctct
     4201 attctgacag tagccttgaa agcttttgaa aaacatatgg gacaaggaga taagaaataa
     4261 tgacagaaac cttgataaaa attgaaaatt tacataaatc ttttggaaag aatgaagtat
     4321 tgaagggcat cagcctcgag attaaaagag gagaagttgt cgttatcatc ggtccttcag
     4381 ggagtgggaa atctaccttg cttcgctcta tgaatttgtt ggaggaagca accaagggga
     4441 aggttatctt tgagggagtc gatattacgg acaagaagaa tgacctgttt gccatgcgtg
     4501 agaagatggg catggttttc caacaattta acctctttcc taatatgact gtgatggaaa
     4561 atattacctt gtcacctatc aagactaaag gtgaaagcag ggaagttgct gagaagagag
     4621 cccaagagct tttggaaaaa gttggtttgc cagataaggc agacgcttat ccacagagtc
     4681 tgtcgggtgg gcaacaacaa cggattgcca tcgcgcgtgg gttggctatg gaaccagatg
     4741 ttttgctctt tgacgaacca acttcagcct tggatcctga aatggtaggt gaggtattgg
     4801 ctgttatgca agaccttgcc aagtcaggga tgactatggt tatcgtaaca catgagatgg
     4861 gatttgcccg tgaggtggca gatcgtgtta tctttatggc agacggtgtg gttgttgaag
     4921 atgggacacc tgagcagatt tttgaacaaa cccaagaaca acggactaaa gatttcttga
     4981 gaaaggtttt ataatctatt ttaaaatttc aagacaagat tagtgaaaag ttcaaccaga
     5041 gctttttctt atagtttgaa actataggat aacctaggaa agaagtgtta gagggcacta
     5101 gcagtttttg gtataatgga agatatttga aagaaaagag aagtgatatg acacagatta
     5161 ttgatggaaa agctttagca gccaaattgc aggggcagtt ggctgaaaag attgcaaaat
     5221 taaaggaaga aacagctcta gtgcctggtt tggtagtgat tttggttggg gataatccag
     5281 ccagccaagt ctacgttcgc aacaaggaga ggtcagctct tgcggctggt tcccgtagcg
     5341 aagtagtgcg agttccagag accattactc aagaggaatt gttagacctg attgctaaat
     5401 ataatcagga ttcagcttgg catgggattt tggtccagtt gccattacca aaacatatcg
     5461 atgaagaggc ggttttatta gccattgacc cagaaaagga tgtggatggt ttccatcccc
     5521 taaacatggg acgtctttgg tctggacatc cagtcatggt tccctcgaca cctgcaggaa
     5581 ttatggaaat gtttcatgaa tatgggattg acttggaagg taaaaatgcg gtcgtaatcg
     5641 gtcgttcaaa tatcgttgga aaacctatgg ctcagcttct tttggctaaa aatgcgacag
     5701 taaccttgac ccactcacga actcataatc ttgccaaggt ggctgctaaa gcagatattc
     5761 ttgtagtcgc aatcggccgc gccaagtttg tgactgctga ctttgtcaaa ccaggtgcgg
     5821 ttgtcattga cgttgggatg aaccgagatg aaaatgggaa gctctgtgga gatgttgatt
     5881 atgaggcagt tgcaccactt actagccata tcacgccagt ccctggaggt gtcggtccta
     5941 tgaccattac catgctgatg gagcaaactt atcaagcagc acttcggaca ttggatagaa
     6001 aataagagaa acattcgatt aatagagtgt attttctata gctatatcta aaatggcaga
     6061 aatgaatatt aaattttaga tataagatta caaaaggagg tctgcgtctc ctttttattg
     6121 tataataaaa gtgagaggaa aaaaggatga aagtgattaa tcaaacctta ttagaaaaag
     6181 ttattattga acgttctcgt tcaagtcata aaggagatta tggtcgtctg ctgctgcttg
     6241 gtggtactta tccttatgga ggtgccatca tcatggctgc tttagcagct gtaaaaagcg
     6301 gtgcaggatt ggtgaccgtt ggaacggaca gggaaaatat cccggctctg cacagccatt
     6361 tacctgagcc tatggccttt tctcttcaag accagcaatt gttaaaagag caattggaga
     6421 aggcagaagt tgtcttgctg gggcctggtt tacgagacga tgcttctgga gaaaatctag
     6481 taaaacaggt ctttgttaat ttaagccaaa atcagatttt gattgtagac ggaggtgcct
     6541 tgaccattct tgctaggaca agtttgtcat ttccctcaag ccagcttatc ctaactcctc
     6601 accaaaaaga atgggaaaaa ttatctggaa ttacgattga aaagcaaaag gaagatgcaa
     6661 cggctagtgt tctgacttcc ttccctcaag gaacaatttt ggtggagaaa ggcccagcta
     6721 ctcgtatttg ggaagttggc caatctgatt attaccagtt acaggttggt ggtccttatc
     6781 aggcgactgg gggaatggga gatactctgg ctgggatgat cgcaggattt gtaggccaat
     6841 tccgacaggc cagtctctac gagcgtgtgg cagtagcgac ccatcttcat tcagccatag
     6901 cccaagaact atctcaagaa aattatgtgg tcttaccgac ggaaatcagc aggtatcttc
     6961 ccaaaataat gaaaattatt tgtcaacaag agagggtaag taaagataaa cttgtttaaa
     7021 atagacagat aaatctactt ccttctctta atttatgatt cttgaaatgc gcctgcttta
     7081 aggctaaact agacgtatca aagttaagag tttgtttttg taactggaaa gagatgaaca
     7141 aatcaaatac ataaaagata aactcatttt tattcgtttg gtgaaaagaa aatacatatt
     7201 tttaaagaaa gattgatgaa aaatgtagat ttgatgtttt tacttgaata aaaagcggtt
     7261 tcatagtaaa ataagaactg agaatgatgg aggtaaatcg gtggaaaatc tgaagaaaat
     7321 ggcaggtatc aaggctgctg agttcgtgag cgatggaatg gtcgttggac tgggaacggg
     7381 ttctactgcc tattattttg tcgaagaaat tggtcgtcgt atcaaggaag aaggattgca
     7441 gattacagct gtaacgactt ctagtgtgac cagtaaacag gctgaagggc ttaacattcc
     7501 actcaagtct attgaccaag tagactttgt cgatgtgaca gtcgacggag cggatgaagt
     7561 agatagtcag tttaatggaa tcaaaggcgg tggtggtgcc cttctgatgg agaagattgt
     7621 tgcaacgccc tcaaaagaat acatttgggt agtggatgaa agcaagctgg tagacaaact
     7681 aggtgctttt aaattgcctg tggaagtggt tcaatatggt gcagaacaga tttttcgtcg
     7741 ttttgagcga gctggctaca aaccaagttt ccgtgaaaaa gatggccaac gttttgtgac
     7801 cgatatgcag aactttatca ttgaccttgc cttggatgtc atcgaagatc caattgtttt
     7861 tggacaagaa ttggaccatg tcgttggtgt tgtagaacac ggtttattca accaaatggt
     7921 ggacaaggtc attgttgctg gacgagatgg ggttcagatt ttaacctcaa gaaaagaaaa
     7981 atagaagggg gcataagatg tctaaattta atcgtattca cttggtggta ttggattctg
     8041 taggaattgg tgctgcacca gatgctaata actttgtcaa tgcaggggtt ccagatggtg
     8101 cctctgacac actgggacac atttccaaaa ccgttggttt gaatgtccca aacatggcta
     8161 aaatcggtct tggaaatatt cctcgcgaaa cgcctttgaa gactgtagca gctgaaagca
     8221 atccaacagg atatgcgacg aaattggaag aagtatccct tggtaaggat accatgactg
     8281 gtcactggga aatcatggga ctcaacatta cggagccttt cgatactttc tggaacggat
     8341 tcccagaaga aatcctgaca aaaatcgaag aattttcagg acgtaaggtc attcgtgaag
     8401 ccaacaaacc ttactcagga acagctgtta ttgatgactt tggaccacgt cagatggaaa
     8461 ctggagagtt gattatctat acttcagctg accctgtttt acaaattgct gcccacgaag
     8521 acatcattcc tttggatgaa ttgtaccgta tctgtgaata cgctcgttcg atcactcttg
     8581 agcgccctgc ccttctaggt cgtatcattg ctcgccctta tgtaggtgaa ccaggtaact
     8641 tcactcgtac agccaaccgt cgtgacttag ccgtttctcc atttgcaccg actgttttgg
     8701 ataaattgaa tgaagctggt atcgatactt acgctgttgg taaaatcaac gatatcttta
     8761 acggtgctgg tattaaccat gacatgggtc acaacaagtc aaacagccat ggaattgata
     8821 cactattgaa gaccatgggt cttgctgagt ttgaaaaagg attctcattc acaaacttgg
     8881 tggactttga tgccctttac ggccaccgtc gtaatgctca tggttatcgt gattgcttgc
     8941 atgagtttga tgaacgcttg cctgaaatta tcgcagctat gagagaaaat gaccttctct
     9001 tgattactgc ggaccacggg aacgacccaa cttacgcagg aacagaccac actcgagaat
     9061 atatcccact tttggcttac agtcctgctt ttaaaggaaa tggtgtcatt ccagtaggac
     9121 attttgcaga tatttcagcg actgttgctg ataactttgg tgtggaaact gctatgattg
     9181 gggaaagttt cttagataaa ttggtataag atgacgcgct atgctttgct ggtgagaggt
     9241 atcaatgttg gtggtaagaa taaggtcgtc atggcggagc ttcgtcaaga attgacaaac
     9301 ttgggactgg aaaaggttga gagctacatc aacagtggca atattttctt tacttcgata
     9361 gattccaaag cccaattggt tgaaaagcta gagactttct ttgcagtcca ttatccattt
     9421 attcagagct tttctttact gagtctagag gactttgagg cggaacttga aaatctacca
     9481 gcttggtgga gcagagattt ggcacgaaaa gattttctct tttacactga gggtttggat
     9541 gtggaccaag tcatcgcgac agttgaaagt ttagagctga aagatgaagt gctttatttt
     9601 ggaaaacttg ggattttctg ggggaaattt tctgaagaat cctattctaa gactgcctat
     9661 cagaagtact tgctgaaggt gcctttctac cgccacatta ctattcgtaa tgctaaaacc
     9721 tttgacaaaa ttggtcaaat gctaaaaaaa taataaagga gacacacaat gacattttta
     9781 aacaaaatcc atgaaactgc tactttcctg aaagaaaagg gaattgcagc ccctgagttc
     9841 ggtctaatcc ttggatcagg acttggagaa ttggcagaag aaatcgaaaa tccagttgta
     9901 gtagactatg ctgagattcc aaactggggc cgttcaacag tagtcggtca tgctggtaaa
     9961 ttggtatatg gtgaactggc aggtcgcaag gtcttggctc ttcaaggtcg tttccatttc
    10021 tatgaaggga atcctctgga agtggtgact ttcccagttc gtgtgatgaa agttcttgga
    10081 tgtgaaggtg ttattgtaac caatgcagct ggcggtatca gatttggtcc tggtaccttg
    10141 atggctatct cagaccatat caacatgacg gggcaaaatc cattgatggg tgaaaacttg
    10201 gatgactttg gcccacgttt cccagatatg tctagggcct acacaccaga ataccgtgcc
    10261 actgcccatg aagtggctaa aaaacttaat atcaagcttg atgaaggtgt ctatatcgga
    10321 gttactggtc cgacttatga aacaccagca gaaattcgtt cctataagac actgggagca
    10381 gatgcagttg gtatgtctac ggttcctgaa gttatcgtgg cagcccactc tggcttgaaa
    10441 gttctgggaa tttcatgtat cactaacttt gcggctggtt tccaagaaga actcaatcac
    10501 gaagaagttg tagaagtgac tgaacgtgtt aaaggtgatt tcaaaggctt gcttaaagcg
    10561 attcttgctg aattgtaaga aaaaagattt aaaaggggta gtgcctctgt cttttcagga
    10621 ttgactgcct atccgtatta aagaagaaac agaggaatac tatgagcttc ttcctgctct
    10681 tataactgaa agaagcggaa gaataggtat gtctgatctg atagccagca ttgtgaaaga
    10741 caagattcta ggatactagc attagctttc tagccaagca gactagtatg ataaggagag
    10801 atgagaatga attgactttc tgaatttctc agtcttatca tatatagcac aatgagattt
    10861 cgcttgagtc tgcttgtaaa taaacgaaaa gaaagataat aaataatgaa aattggtcaa
    10921 cgaattatgc gctttggtat aaaaaattaa gtatcggagt tgtatctgtt gtagtcggct
    10981 ttgatttcta gctccagctg gaatttcagc caatgaagta aagcaagatg taacatctga
    11041 agtggtaata ggtgtgctag attctaagga ggaattgaaa gagtcagaaa atgatgctcc
    11101 aaaactagaa actcctctta gagaggagcc aagactagct cctcaaacgc ttccggaagc
    11161 aagtgaagtt cttgaaaaca aaagggaaga gtcaaaagta gagataacag agccagctca
    11221 agcggatgat atccgcaagg ttgttgggga attagccaag gatataagta ttactaagtt
    11281 gtatatgaca ggtcattctc ttggaggcta cctagctcag attgcagcgg ttgaagatta
    11341 ccaaaaatat cctgattttt ataaccatgt attgaggaaa gtgacaactt tcagtgctcc
    11401 taaagtcatt acttccagaa ctgtttggga tgctaagaat ggtttctgag atgttggttt
    11461 ggaaagtcgt aaattagctg ttagtggaaa aattaagcat tatgtggttg ataatgacaa
    11521 tgttgtgact cccttgattc ataataatcg tgatattgtt acatttacag gtaattcacg
    11581 ctttaaacac cgttctcgtg gctattttga aagtccaatg aatgatattc ctaactttaa
    11641 tattggtaaa caagctacct tggataaaca tggttatcgt gatccgaaat tggataaagt
    11701 gcgattcttt aagaaacagg ctctgcctcg atcttctagt caaccaagcg ctgaaccaat
    11761 ggaaaatatt gccttaggaa aacaggttac tcaaagttcg acagttttcg gaggagatgc
    11821 tagaagagct gtggatggca aagtcgatgg taactatggt cacaattctg tcactcatac
    11881 aaacttccaa tctaagcctt ggtggcaagt agatttggct aaagaagaaa ccattcgcca
    11941 aatcaatatt tacaaccgaa cagacactgc ccaggataga ttggcaaact ttgatgtcat
    12001 tcttttagac agttctggta aagaaattga gtgaaaacgt ataacatctc ctaaagatgt
    12061 gtcagcacaa attacgatta accataaaaa agtgcgctat gttcggattg agctagaagg
    12121 ctataatgcc ctcagtcttg cagaagttga agttttccgc tttatagcta cgaatgctga
    12181 aacggcgaca caagtttcta agccagttca accaatcagt cagactcctg tgaaagataa
    12241 aacattgaca attcaacaca gtggagctta cattgcccgc tactccataa cttgggaaga
    12301 agttccagta gataaagatg gaaaccaagt tgttcgtagt cattcttggg aaggaaacgg
    12361 ttgcaaccag actgcaggtt ttgtcctcaa cctcccaatc aaagaaaata tgagaaatct
    12421 gcgagttaag attgagaaaa agacgggcct actatggaat agatggcaaa caatctatga
    12481 aaacagacca attttagctc aaccccaccg taaaattacc cattggggta cgacattgaa
    12541 ttccaaggtg agtgacgatg atgtcttgta atctgatggt acaatgacag ttagtttgtc
    12601 tagtttataa gaaagtacta cctgagcttg aatagaactc aggtagctct ctgtgaaaga
    12661 acaaaatt
//
LOCUS       DAVAGB010000050        12433 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVAGB010000050 DAVAGB010000000
VERSION     DAVAGB010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12433
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.051"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            737..1264
                     /locus_tag="VQO19_001745"
     CDS             737..1264
                     /locus_tag="VQO19_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349970.1"
                     /translation="MLIVSAIPSVSAVYASEQVSQIETNMELQPVTSLTEEQINTLAN
                     EIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGITVNQMGALLDTAIALA
                     LGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALEFAMNLLSPGTYLAQL
                     WDKNDAIPNNGRINF"
     gene            complement(2309..4567)
                     /gene="glgP"
                     /locus_tag="VQO19_001746"
     CDS             complement(2309..4567)
                     /gene="glgP"
                     /locus_tag="VQO19_001746"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HET1349971.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINSNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(4593..6110)
                     /gene="malQ"
                     /locus_tag="VQO19_001747"
     CDS             complement(4593..6110)
                     /gene="malQ"
                     /locus_tag="VQO19_001747"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HET1349972.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            6660..7931
                     /locus_tag="VQO19_001748"
     CDS             6660..7931
                     /locus_tag="VQO19_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET1349973.1"
                     /translation="MSSKFMKSAAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            8042..9334
                     /locus_tag="VQO19_001749"
     CDS             8042..9334
                     /locus_tag="VQO19_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET1349974.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            9336..10178
                     /locus_tag="VQO19_001750"
     CDS             9336..10178
                     /locus_tag="VQO19_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET1349975.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            10431..11231
                     /locus_tag="VQO19_001751"
     CDS             10431..11231
                     /locus_tag="VQO19_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HET1349976.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTDKVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            11241..12227
                     /locus_tag="VQO19_001752"
     CDS             11241..12227
                     /locus_tag="VQO19_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET1349977.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
BASE COUNT         3788 a         2589 c         2276 g         3780 t
ORIGIN      
        1 atctgcaacc tcaaagctgt actttgagca acctacggct agtttactct ttgattttca
       61 ttgagtataa actagacttc gcaaaagtag aaaacttacc gaaaatcttc aatatgacaa
      121 aaacgtataa gaacaggtac acaaacctta atcttatgcg ttttgttata gtttccatac
      181 gcattaaggg gaaatagttg aaatcagttc ttttaataac cattgaatac catatactac
      241 atttacccca aatatgatat aggccgtata aatcaagtat ttcgattttt cccgcctcaa
      301 agaatagatc ttatacaaaa taaataaatt taaaataata aataatagag acaaaatctt
      361 cctccaaaat caatcctaaa agtacacagt caagcatagc tctaatcttt attttcgatt
      421 cgaaattaca aacttatcaa tgaacaataa gtgatataag gtcagtacca aaccccaaaa
      481 gctaccacga aaagagaatt cttgatgatt gagagtaaac aaatcatggt taccaatata
      541 gaggcaggtc aaaataacaa ataaaatcca aaataaatcc gtccatttat attttgaaaa
      601 atattttttt aacataatag catatttttc ttgactataa taacagtata taataaaatg
      661 taagcagata caaataaaaa ggagaaaagc tcatgaacaa attaatgaaa tttattttgg
      721 ttttttgacg tcaattgtgt taattgtatc agcgattcca agtgtttcag ctgtatacgc
      781 ttctgaacaa gtatcgcaaa ttgaaacaaa tatggaactt caacctgtca cttctctaac
      841 agaagaacaa atcaatacac ttgcaaacga aatccaatct tttcatccag acgtctcaca
      901 acaatggatc aaagaagtaa ttaaccgaca attacaaggc gattatacaa tcccacctac
      961 atactctcca tttagagcag cttggcaagg tattacagtt aatcaaatgg gtgctctatt
     1021 agatactgca atagctttag ccttaggagg aactactgca ggccttgcaa atctaattaa
     1081 agtaaaagga aaacatgcag caaaaagtgc tattcgttca gcaatttcta gatatctagg
     1141 tagttggttt gtaaatgatg ttgctttaga attcgctatg aatttattat caccggggac
     1201 ttatttagca caattatggg ataaaaatga tgccattcct aacaacggaa ggattaactt
     1261 ttaatcatga gatatacaat aaaattaatt gggtataacg tattttcgtt gtttatattc
     1321 tttatcttat caatgttgtt taaagttccc tttaggtggt ggatcagcat tgcaatgacg
     1381 acttcgtcgt acattgtata taattactta aagaaaaaga gagaaaagga atgatcttat
     1441 accagatcat tccttttctg ctttctgtaa atccctcgga gtgtgtttgg cgctttgata
     1501 cgaagtgtca aagctgtata aacgttacta tttccaaaaa agtaacagaa aattcctgct
     1561 ttgtaggact gctttgggtg agtaatagac atgtcgactc accctatctc ctgatggcga
     1621 aaagaattta gcaatgatgc aagttgttct gaactcgaga aaaaacatgc cgaaatcgaa
     1681 gaaaagcgtg cagaacttga agcgaagaag caagaaatgt tgaagcgctt ggataaatag
     1741 aatttagaaa acagaaaaaa ctaaaaagaa tgtagggttt atttccctac attcttaaaa
     1801 taacttagta cataaatgac aatgctgcca ctgccgtcaa tattgcaaaa actattttcc
     1861 aaattttttt attttttcca aaaatcttat caggtaacaa gcttattaca agaaaggtaa
     1921 taaacaacac caatttaagt gtgtatatca taaaaacacc ttctttccta caattatatt
     1981 ataatacttt atgtaagcga atacaagaga tatgaggtaa ccaactacga aaaaatataa
     2041 ggctgaagac agtaaaaacc agcatttaaa gccttcactg tatctaggat ttccctattt
     2101 ttagacaaga ttgacccaaa tccacagcat ttaaaaaagc gaatttcaat cgaaactcgc
     2161 ttttttacaa gatgtattag tataaatttg tatcttatac tcaatgaaaa tcaaagagca
     2221 aactaggaag ctagccgcag gttgctcaaa gcaccgcttt gaggttgcag ataaagctga
     2281 cgtggtttga agagattttc gaagagtatt agttcaagtg ccagatgtct tcgttatact
     2341 gagcgattgt acggtcagat gagaagaatc ctgctttaga aatgttaacg atgactttat
     2401 ccaaccatgc gtcacggtct tcgtagtcag caagcatttg ctctttgact ttgatgtagt
     2461 cttccaaatc aagaagagtc atgaaccagt ctttgttgat caattcattg taaagacgtt
     2521 ccaagcgctc tttgtttcca gctgcaagaa ctgcatcact aacgatgaag tcaaccaatg
     2581 gtttgatagc ttcacgagcg tagaattcgc ttgatttgta agctgctttt gcgtaaaggt
     2641 cgataacagt ttctgaatct tcaccgaaga tgtagatgtt ttcttctcca accaactcag
     2701 cgatttccac gttagcaccg tccatagtac caagtgtcaa agctccgttc aacatgaatt
     2761 tcatgttacc agtacctgaa gcttctttag aagcaagtga gatttgttct gagatatcac
     2821 atgctgggat aaggaaactt gctgcagtaa cgttgtagtt ttcaaccata actacttgca
     2881 agtgtggagc tactgctgga tcgttagcaa taacttctga catgcaaagg attaaatgga
     2941 taatgtcttg agcgattgtg taggctggag ctgctttacc accaaagaag attgtgattg
     3001 gacgagcagg gatgttacca gctttgatgt caaggtattt gtggatcacg tacaaagcgt
     3061 tcatttgttg gcgtttgtac tcatgaagac gtttgatttg gatatcaaag atagaatttg
     3121 aattgatttc cacaccttgg tgttctttca agtgacgagc caatttacgt ttgttgtgag
     3181 ccttgatgct ttccaatttt tctttgacag ctgctttgtc ttcataagac aaaagttttt
     3241 caagctcatc tgcttcatgg tgccaaccat ctccaagaat ctcatctaag tagtgagaca
     3301 atcttgggtt agcatgcata agccaacgac ggaaagtgat accgtttgtt ttgttgttga
     3361 acttttctgg gtaaaggtcg tagaaggctt tcaactcaga atttttcaag atttcagtat
     3421 ggagtgctgc aaccccgtta acactgtatc cgtagtggat atccatgtga gccatgtgaa
     3481 cacgtccgct ctcatcgatg atttgaacag ctggatcttt gtactctgcc ttcacacgac
     3541 ggtccaattc ttcgatgatt ggtaccaagt gaggaaccac ttcttgcaag aattcaagag
     3601 gccatttttc aagcgcttca gcaaggattg tgtggttagt gtaggcagtc atgctacgaa
     3661 caattgagat tgcttcgtca agctcgatac cacgtgcagt taaaagacga atcaattcag
     3721 gaatcaccat tgatgggtga gtatcgttga tttggacaac tgcgtagtca gcaaggtcat
     3781 gcaagttgct tcctttttcg attgcttcgt cgatgatcaa ttgcgcaccg tttgaaacca
     3841 tgaagtattg ttggaagata cggagcaatt caccttgacg gtcactatca tctgggtaaa
     3901 ggaagagagt caagttgcga gcgatatctg tcttgtcaaa gttgatacca tctttaataa
     3961 tagaagaatc aactgaatcc aagtcaaaca aacgcaagcg gtttttagtc gctgtttcat
     4021 aaccagtaac atcaatatcg taaagagttg atgtcaaagt aaagtctgca aatggtactt
     4081 ggtagctacg gcttgagcga accaaccagt tttgctctgt caaccatgca tttggaattg
     4141 tttcttgttg gttgttttta agaacttgtt ggaaaagacc aaagtggtag ttaagaccaa
     4201 caccgtcacc attcaaacca agagtagcaa ttgagtcgat aaagcaggca gccaaacgtc
     4261 ccaaaccacc attaccaaga gatggttcca attcaacttc ttcaacttcg atcaagtctt
     4321 tacctgcagc tgcaagttct tttttaacat cgtcgtaaag accaaggtta atcaagttgt
     4381 ttgacaagag tttaccaatc aagaactcag ctgagatgta gtaaactttt ttcttaccag
     4441 tgttgactgg tttttggctg cttgcaagct tgctgtagtt aagaagagca aggtaaagct
     4501 cttcattgct acattctgca atggttttat tgtaacgatt ttgtacaaat tcttgtagtg
     4561 ataacatgtt tagttgtctc ctgattattg tcttatttct ttaaatctac caaattttca
     4621 ttaattcggc gataaattgt tgtcaagtca agcaaacctt cctcgacagc tggtgtcaat
     4681 tgatcttcag tcatacgcca agaccagttt ccaccaaggg tagatgggaa gttcatacga
     4741 gctgcctcat ccaattctag taaatcttgc atagttgcaa ttgccataaa gctaactgat
     4801 gaaaatactg tacgaagcat agcgtgtacc actgtttcgt attctttacg gttcgtgtaa
     4861 cgagccatgt actcacgagt cgcatcatca atctcattac ggtaccaacc aagaaccgta
     4921 ttgttatcgt gtgttcctgt gtacataact gagttagcag gtgccaagtg tgggctatca
     4981 atgctttcgt cttctgggtt gaaggcaaat tgaagaatct tcattcctgg gaagccagta
     5041 cgttcacgca attcgatcac ttcatctgtc atgaagccaa ggtcttctgc gatgatgttt
     5101 agctcaccaa gttcttcctt aacggctgca aaaagcttgt agcctggacc tttcacccac
     5161 tcaccaggtg ctgctgtatc ggaaccagca gggatttccc agtaagattc gaagccacgg
     5221 aagtggtcga tacgaacgat atcgtagatt ttgaagcttt cacgcaagcg ttcaatccac
     5281 catttgtaac cgtctttgtc cattgcttcc cagtcataga ttgggttacc ccaaagctga
     5341 ccagttacag aaaactcatc tggtgggcat cctgcgatac aagtagcctt accattgaca
     5401 tctgttttga agagatgtgg atttgcccac atatcacttg aatcttccgc tacgtagatt
     5461 ggcatgtccc caacgatttc gatgtggttg tcgttagcgt aagctttcaa tttcaaccat
     5521 tgttggaaga agaagtattg agtcacacgg tggtaaacca acttgtctgc caattgctca
     5581 cgatagcttt caagtgctga agctttacga gcacgagcat ctgcatctgg ccattcagtc
     5641 caagcaagat tgtcaaaata ctctttgata gccatatact cagcaaagag ctcaagccat
     5701 gattggttgt cttgagcaaa tttctcaaaa tctttaacat ctccgacttc aaagaaacgt
     5761 ttcaccgctt tttctaaaag aggacgacgt gcatagtaga ttttagcata gtcaacttca
     5821 gacgcatcgc taccaaagtc aactccttca aggtcacttg cttccaacaa accttgctcc
     5881 accaagatat ctaaatcgat aaaatgagtg tttcctgcga aggctgagaa agattggtaa
     5941 ggagaatccc cgtaactagt tgctcctaat ggaaggattt gccagtaacg ttgttttgta
     6001 cggaccaaga aatcaacgaa gtcgtaagca ctttgaccaa atgatccgat tccgtaagct
     6061 cctggaagag aagagatgtg catcaacaca ccactttgac gttttttcat aatagcacct
     6121 cgtgtgttaa aataatggaa cgttgcgtat ttttcagacg caaacgtttg cgttacttat
     6181 aagtatactc cttttcaagc ataattgcaa gcgtttttaa aaaacttttt tgattatttt
     6241 taaggagact aactcatttt agcaaagata acttaaaact atctaatcct aaagtttgac
     6301 tctcacgaga cagtctacaa agtacaaaac ctccttaggg agcttgaatt tatatgcaat
     6361 aaagcacaaa cgtctataga aaatagatat agattagaaa cagggaggta gcccctcctg
     6421 atttccctct ttagacagat tccatatatt tttattaaaa atactgtatt cttatctatt
     6481 tcatactttt cttctattaa aatgcaaaat tatgctatca aatcaagctt aaaaattttt
     6541 taaaattttt acaaaaaata cttgcaaccg ttttctattt gtgctatact aagctcataa
     6601 aggaaaacgt ttgcgtttcc ttatcaataa aacttgctat tctttaggag gaatacacta
     6661 tgtcatctaa atttatgaag agcgctgcgg tgcttggaac tgctacactt gctagcttgc
     6721 tcttagtagc ttgcggaagc aaaactgctg ataagcctgc tgattctggt tcatctgaag
     6781 tcaaagaact cactgtatat gtagacgagg gatataagag ctatattgaa gaggttgcta
     6841 aagcttatga aaaagaagct ggagtaaaag tcactcttaa aactggtgat gctctaggag
     6901 gtcttgataa actttctctt gacaaccaat ctggtaatgt ccctgatgtt atgatggctc
     6961 catacgaccg tgtaggtagc cttggttctg acggacaact ttcagaagtg aaattgagcg
     7021 atggtgctaa aacagacgac acaactaaat ctcttgtaac agctgctaat ggtaaagttt
     7081 acggtgctcc tgccgttatc gagtcacttg ttatgtacta caacaaagac ttggtgaaag
     7141 atgctccaaa aacatttgct gacttggaaa accttgctaa agatagcaaa tacgcattcg
     7201 ctggtgaaga tggtaaaact actgccttcc tagctgactg gacaaacttc tactatacat
     7261 atggacttct tgccggtaac ggtgcttacg tctttggcca aaacggtaaa gacgctaaag
     7321 acatcggtct tgcaaacgac ggttctatcg taggtatcaa ctacgctaaa tcttggtacg
     7381 aaaaatggcc taaaggtatg caagatacag aaggtgctgg aaacttaatc caaactcaat
     7441 tccaagaagg taaaacagct gctatcatcg acggaccttg gaaagctcaa gcctttaaag
     7501 atgctaaagt aaactacgga gttgcaacta tcccaactct tccaaatgga aaagaatatg
     7561 ctgcattcgg tggtggtaaa gcttgggtca ttcctcaagc cgttaagaac cttgaagctt
     7621 ctcaaaaatt tgtagacttc cttgttgcaa ctgaacaaca aaaagtatta tatgataaga
     7681 ctaacgaaat cccagctaat actgaggctc gttcatacgc tgaaggtaaa aacgatgagt
     7741 tgacaacagc tgttatcaaa cagttcaaga acactcaacc actgccaaac atctctcaaa
     7801 tgtctgcagt ttgggatcca gcgaaaaata tgctctttga tgctgtaagt ggtcaaaaag
     7861 atgctaaaac agctgctaac gatgctgtaa cattgatcaa agaaacaatc aaacaaaaat
     7921 ttggtgaata aaaaatttgt tcaagggggg tggaaatcaa atcccccttt gaatttatca
     7981 atagagacac aaataattta gctttcttat aaaaaagtag tatcctatga aaggagttaa
     8041 tatggaaaag caacaaccta gtaaagcagc cctgctgtct atcattcctg ggttaggaca
     8101 gatttacaat aaacaaaaag ccaaaggttt tatcttcctt ggtgtaacca tcgtatttgt
     8161 cctttacttc ctagcacttg caacccctga attgagcaac ctcatcactc ttggtgacaa
     8221 accaggtcgt gataattccc tctttatgct gattcgtggt gccttccatc taatctttgt
     8281 aatcgtttat gtactctttt atttctcaaa tatcaaagat gcacatacga ttgcaaaacg
     8341 cattaacaat ggaattccag ttccacgcac actcaaagac atgatcaaag ggatttatga
     8401 aaatggcttc ccttacctct tgatcattcc atcttatgtt gccatgacct tcgcgattat
     8461 cttcccagtt atcgtaacct tgatgatcgc ctttaccaac tacgacttcc aacacttgcc
     8521 accaaacaag ttgttggact gggttggttt gaccaacttt acaaacattt ggagcttgag
     8581 taccttccgt tctgcctttg gttctgttct ttcttggact atcatttggg ctttggcagc
     8641 ttctacttta caaatcgtaa ttggtatctt cacagctatc attgccaacc aaccatttat
     8701 caaaggaaaa cgtatctttg gtgttatttt ccttcttcct tgggctgtcc cagccttcat
     8761 cactatcttg acattctcaa acatgtttaa cgatagtgtc ggtgctatca acactcaagt
     8821 attgccaatc ttggctaaat tccttccttt ccttgatgga gctcttattc cttggaaaac
     8881 agacccaact tggactaaga ttgccttgat tatgatgcaa ggttggctcg gattcccata
     8941 catctacgtt ttgactttgg gtatcttgca atctattcct aacgaccttt acgaagcagc
     9001 ttatattgac ggtgccaacg cttggcaaaa attccgcaac atcactttcc caatgatttt
     9061 ggctgttgcg gcacctactt tgattagcca atacaccttc aactttaaca acttctctat
     9121 catgtacctc ttcaatggtg gaggacctgg tagtgtcgga ggtggagctg gttcaaccga
     9181 tatcttgatc tcatggatct accgtttgac aacaggtaca tctcctcaat actcaatggc
     9241 ggcagctgtt accttgatta tctctatcat tgtcatctca atctctatga tcgcattcaa
     9301 gaaactacac gcatttgata tggaggacgt ctaagatgaa taactcaatt aaactcaaac
     9361 gtagactgac tcaaagcctt acttaccttt acctgattgg tctatcaatt gtaattatct
     9421 atccactgtt gattaccatt atgtcagcct ttaaagcagg taacgtctca gcctttaaac
     9481 tagatactaa tatcgacctc aattttgata actttaaagg cctcttcact gaaaccttgt
     9541 acggtacttg gtacctcaac actttgatta tcgccttaat taccatggct gttcaaacaa
     9601 gtatcatcgt acttgctggt tatgcttaca gccgttacaa cttcttggct cgtaaacaaa
     9661 gtttggtctt cttcttgatc atccaaatgg tgccaactat ggccgctttg acagccttct
     9721 tcgttatggc gcttatgttg aacgccctta accacaactg gttcctcatc ttcctctacg
     9781 ttggtggtgg tatcccgatg aatgcttggc tcatgaaagg ctacttcgat acagtgccaa
     9841 tgtctttaga cgaatctgca aaactagacg gtgcaggaca cttccgccgc ttctggcaaa
     9901 ttgttctacc acttgttcgc ccaatggttg ccgtacaagc tctctgggcc ttcatgggac
     9961 ctttcgggga ctacatcctc tctagtttct tgcttcgtga gaaagaatac tttactgttg
    10021 ccgtaggtct ccaaaccttc gttaacaatg cgaaaaactt gaagattgcc tacttctcag
    10081 caggtgctat cctcatcgcc cttccaatct gtattctctt cttcttccta caaaagaact
    10141 ttgtttcagg acttacaagt ggtggcgaca agggataatt tatccccgcc accctttttc
    10201 attttatact cttcgaaaat ctcttcaaac cacgtcagct ttagctccaa cctcaaagtt
    10261 gtgctttgag caacctgtgg ctagtttgca ctttgatttt cattgattat tagcaattgt
    10321 cactgtaaat aatatccttg tagcaagcaa tttttctcct agacttgaaa taaagcgcat
    10381 ttctctatat aataatactc atatagaaaa caccttttag aaagatacct atgcttccat
    10441 atccattttc ctatttttca agtatttggg ggtttcgtaa gcccctgtcc aaacgtttcg
    10501 agctcaactg gtttcaactt ctctttacca gtatcttcct tatcagcttg tctatggtac
    10561 ccattgctat ccaaaacagc tcccaggaga cctatccgct agaaactttt atcgataatg
    10621 tctatgaacc tctgacagat aaggttgtcc aggatctctc tgaacatgct acaattgtcg
    10681 atggcacatt aacttatact ggaacagcta gtcaagcccc ttctgttgtg attggtccaa
    10741 gtcaaatcaa ggaattacct aaggacttgc aactgcattt cgatacaaat gagctagtca
    10801 tcagcaagga aagcaaggaa ctgacccgca tctcttaccg agccattcag actgagagtt
    10861 tcaaaagcaa agacagcttg acccaagcaa tttctaaaga ctggtaccaa caaaatcgtg
    10921 tctatatcag cctcttccta gttctcggtg cgagcttcct ctttggtttg aatttcttta
    10981 tcgtctctct aggagctagt cttctccttt atatcactaa gaaatcacgc ctcttttcat
    11041 ttagaacctt taaagagtgc tatcacttta tcttgaactg tttaggattg ccgactctga
    11101 ttacacttat tttgggatta tttggccaaa atatgacaac cctgattact gtacaaaata
    11161 ttctttttgt tctgtatctg gtcactatct tttataaaac acatttccgt gatccaaatt
    11221 accataaata ggagattttt atgcccgtta cgattaaaga cgtggccaag gctgctggtg
    11281 tttcgccttc aaccgtaacc cgtgttattc aaaataaatc aaccattagc gacgaaacaa
    11341 aaaaacgcgt tcgcaaagct atgaaggaac tcaactacca cccaaacctc aacgctcgta
    11401 gcttggtaag cagctatact caggttatcg gattagttct tcctgatgac tcagacgcct
    11461 tctaccagaa tcctttcttt ccatcggttc tacgtggcat ctctcaagtc gcatctgaaa
    11521 accactatgc cattcagata gcaacaggga aagatgagaa ggagcgtctc aacgctattt
    11581 cacaaatggt ctacggcaag cgtgtagatg ggctaatctt tctctatgcc caagaagaag
    11641 accctctcgt aaaactcgtc gcagaagaac agttcccctt ccttatccta ggtaaatctc
    11701 tatctccttt catcccactt gtcgacaacg acaatgttca agctggtttt gatgcgactg
    11761 aatatttcat caaaaaaggc tgcaaacgca ttgcctttat cggaggaagt aaaaagctct
    11821 tcgtgaccaa agaccgttta acaggctatg aacaggcgct taaacattac aaacttacca
    11881 ctgacaacaa tcgcatctac tttgccgacg agtttctgga agaaaagggc tataaattta
    11941 gcaagcgatt attcaagcac gatccacaaa ttgacgctat catcacaacc gatagcctcc
    12001 tagctgaagg tgtttgtaac tatattgcca aacaccagct ggatgtccct gttctcagct
    12061 ttgactcggt taatcccaag ctcaacttgg cagcctatgt cgatatcaat agtttagagc
    12121 ttggtcgtgt ttcccttgaa actattctcc agattattaa tgataataaa aacaataaac
    12181 aaatttgtta ccgtcaattg atcgcccaca aaattatcga aaaataagag actgggcaaa
    12241 gagtcgttaa aagcaaaaac gcatactatc aggtattgaa aaaacttgat actatgcgtt
    12301 ttattgtggg aagatttact tccttttcta ctgaaattga gtcttttccc aagatctttt
    12361 tatactcaat gaaaatcaaa gtgcaaacta ggaagctagc cgcaggttgc tcaaaacact
    12421 gttttgaggt tgt
//
LOCUS       DAVAGB010000051        12260 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVAGB010000051 DAVAGB010000000
VERSION     DAVAGB010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12260
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.052"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            1..609
                     /locus_tag="VQO19_001753"
                     /pseudo
     CDS             1..609
                     /locus_tag="VQO19_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            759..1013
                     /gene="blpM"
                     /locus_tag="VQO19_001754"
     CDS             759..1013
                     /gene="blpM"
                     /locus_tag="VQO19_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HET1349978.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            1029..1232
                     /gene="blpN"
                     /locus_tag="VQO19_001755"
     CDS             1029..1232
                     /gene="blpN"
                     /locus_tag="VQO19_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HET1349979.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            1476..1625
                     /gene="blpO"
                     /locus_tag="VQO19_001756"
     CDS             1476..1625
                     /gene="blpO"
                     /locus_tag="VQO19_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HET1349980.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCTAGVAYGAIDG
                     CATTV"
     gene            1729..1848
                     /locus_tag="VQO19_001757"
     CDS             1729..1848
                     /locus_tag="VQO19_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET1349981.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            2634..3017
                     /locus_tag="VQO19_001758"
     CDS             2634..3017
                     /locus_tag="VQO19_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET1349982.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVFYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            3069..3758
                     /locus_tag="VQO19_001759"
     CDS             3069..3758
                     /locus_tag="VQO19_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET1349983.1"
                     /translation="MKKYQLLFKTSAILSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            3800..4033
                     /locus_tag="VQO19_001760"
     CDS             3800..4033
                     /locus_tag="VQO19_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1349984.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            4184..4795
                     /locus_tag="VQO19_001761"
     CDS             4184..4795
                     /locus_tag="VQO19_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET1349985.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            4956..5750
                     /locus_tag="VQO19_001762"
     CDS             4956..5750
                     /locus_tag="VQO19_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HET1349986.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5747..6382
                     /gene="trmB"
                     /locus_tag="VQO19_001763"
     CDS             5747..6382
                     /gene="trmB"
                     /locus_tag="VQO19_001763"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HET1349987.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            6508..6987
                     /gene="rimP"
                     /locus_tag="VQO19_001764"
     CDS             6508..6987
                     /gene="rimP"
                     /locus_tag="VQO19_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HET1349988.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            7031..8167
                     /gene="nusA"
                     /locus_tag="VQO19_001765"
     CDS             7031..8167
                     /gene="nusA"
                     /locus_tag="VQO19_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HET1349989.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            8189..8482
                     /locus_tag="VQO19_001766"
     CDS             8189..8482
                     /locus_tag="VQO19_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HET1349990.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            8475..8774
                     /locus_tag="VQO19_001767"
     CDS             8475..8774
                     /locus_tag="VQO19_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HET1349991.1"
                     /translation="MNKQKISNLLGLAQRAGRIILGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8791..11583
                     /gene="infB"
                     /locus_tag="VQO19_001768"
     CDS             8791..11583
                     /gene="infB"
                     /locus_tag="VQO19_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HET1349992.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQVAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            11834..12184
                     /gene="rbfA"
                     /locus_tag="VQO19_001769"
     CDS             11834..12184
                     /gene="rbfA"
                     /locus_tag="VQO19_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HET1349993.1"
                     /translation="MVNHFRIDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKS"
BASE COUNT         3792 a         2141 c         2769 g         3558 t
ORIGIN      
        1 cacttatgaa gaaattgcgg ctgatcttgg tattcacgaa agcaacttaa tccgtcggag
       61 ccaatgggtt gaagtaactc ttgttcaaag tggtgttacg atttcaaaaa ctcatcttag
      121 tgctgaggat acggtgattg tggatgcaac agaggtaaaa ataaatcgtc ctaaaaaaat
      181 caactagcca attattctgg taaaaagaaa tttcacgcta tgaaggctca agcgattgtc
      241 acaagtcaag ggagaattgt ttctttggat atcactgtga actattgcca cgatatgaag
      301 ttgttcaaaa tgagtcgcag aaatatcgga caaactggta aaaccttggc tgacagtaat
      361 tatcaagggc tcatgaagat atatcctcaa gcacaaactc cacgtaaatc cagcaaactc
      421 aaaccgctaa cagttaaaga taaagcctat aaccatgcgt tatctaagga gagaagcaag
      481 gttgagagca tccttgccaa agtaaaaacg tttaaaatgt tttcaacaac ctatcgaaat
      541 catcgtaaac gcttcggatt acgaatgaat ttgattgctg gcattatcaa tcatgaacta
      601 ggattctagt tttgcaggaa gtctaatgta atttttgcaa ttcaagacgt ttcgatgact
      661 attcaagatc tggatgaaaa attttaaaaa acgatgatat actaaacttg tcaaagttac
      721 aacaagacaa aaattaaaaa taaaaaagag tatttgtcat ggatacaaaa attatggaac
      781 aatttcatga aatggatata actatgttat ctagtattga aggaggcaag aataattggc
      841 aaactaatgt cttagaaggt ggtggtgctg cttttggtgg ctgggggcta gggacagcta
      901 tttgtgctgc gagtggtgtt ggagcaccat ttatgggagc atgtggatac ataggagcta
      961 aatttggtgt ggatctttgg gcaggagtaa caggggcaac gggtggattt taataaaagg
     1021 agacttgtat gaatacttat tgtaatataa atgaaacaat gctgagtgag gtttatggag
     1081 gtaattccgg aggagcagct gtagttgctg ctttaggttg tgcagcgggt ggagtgaaat
     1141 atgggagact tctaggacca tggggcgctg caataggagg aattggagga gcagtggttt
     1201 gtggatattt agcctatacc gctacatcat aaaaatgaaa gctaaatttt atgaaggcta
     1261 tattctttat tattctcttc gcttttcaaa cctatcttat ttatctatcc ataagtatct
     1321 ccgataaaaa acaaaagact attgaattaa catcattgaa ttgttttgtc atattatttc
     1381 taatctatga taaattaatt tttctcttta ttgcctatgt ttttttgata atttttatat
     1441 taaacttgtt ccgtaactga aaagtgatat actatatgga tacaaaaatg atgtcacaat
     1501 ttgcagttat ggataatgaa atgcttgctt gcgttgaagg tggagatatt gattggggaa
     1561 gaaaaattag ttgtacagca ggggttgcat atggcgcaat tgatgggtgt gcaacaacgg
     1621 tttgacattt ctattgggac catttgctat aggaataggt gtaactggtg ctgcaggtgg
     1681 agctatactt ggaggtgtag cctatgcagc aatatgttgg tggtaattat ggattttaaa
     1741 agttttatta ttggtttagt agttggtata tttggtcctt atatggatga cttaattaga
     1801 aaaatatttt caaaatcttc caaaaaggat acggatagta ctctctaaaa aataaatttc
     1861 tcccctgtat ttgctagctt aatttacagg ggagtttctt taatattgtt tcgcctgtca
     1921 aaatgatatg tgatagcagg atgaaaagtc tacaaacaag ttggtatcaa tacaatataa
     1981 agaggaaagt atgtttttaa tgcttacttt ttaaattttt taacaattca agatgtttcg
     2041 atgacaattc aagatttgga tgaaaaattt taaaaaacaa tgatatacta aacttgtcaa
     2101 agttgcaacg ggtgctgcta cattatgtta aaaatcgctc ttgattgata agctggattt
     2161 gttaggaaag gagtaaataa ttatggataa gaaaaagata gtttcgacta taatatgtat
     2221 agtatttctt gtagtgtcag tagataattt ttttagagac ttaaccccgt tactgttcat
     2281 tttaaatatt attggcctgt cttgcttttc agtgctaaca tacattaaca taaaagagat
     2341 actcttaaat ataagtaaat gatgatttgg ttagtcctag aaccaatcaa cttatgttta
     2401 tcggcttggc agattttatg tttgtcattt gtttgtatag aggtatttca gaaacagaat
     2461 tctatcaaca actaatcgct tatataggtg tattctctgc ttgtttatca cgcttctgct
     2521 catgtggggc ttgaagtatt ataaaaagta gctttctatc cttttctgac aggatatttg
     2581 agtagaaggc tctattaaat tgttagtgaa ataaatgaat ggaggtattt aatatgaaat
     2641 acagattatt ttttgttatt ttcttgagta gtgtgttgga tattctttta gggacatttt
     2701 tacaaatctc tatcgtatct attgggtggc ttgtttttta cagtggtttg tttgaagcag
     2761 gagttttcct tcttgctaat aaaggggtgg cggtaaaaat caaggaagta gatattcgaa
     2821 atcgctttaa atttattttt ggaaaaacct tatggtttca aattcttttg ctcatctttt
     2881 tgataatcaa actttatctt ggtttggatg cgaggttgat tttattctat ggacatattt
     2941 tcattgtctt taatgcctta atgtatctat tatctagtag tcaggttagc cttaaaaaaa
     3001 acaaactgtc ttcttaatct tacagcagta gagcctgaca aggtgaggtc atagtaggga
     3061 ggatttctat gaaaaagtat cagcttctat tcaaaacaag tgcaatttta tcctacctat
     3121 ttttcgtatt tggtctttct cagctgacgc ttatcgtcca aaactattgg caattttctt
     3181 ctcagatagg caatttattc tggattcaaa atatcttgag tttacttttt attggagtca
     3241 tgattgtggt tcttgttaag acaggccatg gttatctctt ccgcattcca agaaaaaaat
     3301 ggctttggta ttcgattttg acagtattag tggtagtgtt ccagatctct tttaacgttc
     3361 agacagctaa acatgttcag tcaactgcgg aaggttgggc tgtattgatt ggttatagtg
     3421 ggactaactt tgcagagcta ggtatttata tagccctgtt ctttctggtt ccactgatgg
     3481 aagaattgat ttatagagga ctactgcaac atgctttctt taagcattcg cgatttggtc
     3541 ttgatttgct tcttccttct attttatttg ctctccctca tttttcaagc ctgcctagtc
     3601 tgttagatat cttcgtcttt gcaacagttg gaatcatctt tgctggtttg acccgctata
     3661 ccaagagcat ttatccatcc tatgcggtgc atgtgatcaa taatattgta gcgaccttcc
     3721 cgtttttgct cacttttcta catagggtct tggggtaaaa aaacaaaagg cttgcttttc
     3781 agccatagag gaggtcatca tgtataaaca cttatttttc ctagattcca aaactttaga
     3841 tcggttgaca ccctatattc tagtcttggc ttctgacacc attgctttta atgtttttgt
     3901 gctaaccttt gtatctgcgg tggtttttaa tttcctaaat tccatgctag ctttaatggc
     3961 tatattcata ggggctggct atgtggtcgg attttggtta ctaatactca atgaaaatca
     4021 aagagcaaac taggaaacta gccgcaggct gtacttgagt acggcaaggc gacgttgacg
     4081 tggtttgaat ttgattttcg aagagtataa aatggtttgt tttggaaagg ctagaactaa
     4141 agaatgacgt gtaggaagtc tgtttgttga ggaggataat tttatggagt tttttgataa
     4201 atttcatgcc ttgtgttttg gatttttagt actaataatt gtcattacag ttccttatac
     4261 gattaaccat gggggttttt ttcaaaatga atctgcattg attcttgtaa gtcttcttgt
     4321 aacctcgctg agtgttgctt atgctagaaa gtttgaaatg atttcttttg ggatgttaag
     4381 caagaaacaa cttttgcttt tcattgcaat ctttcttcta agtgtacttg agacgctggt
     4441 ttatattcat ttcttcgctg tttcttctgg ctcaggggtc caacacttgg cggaagtcag
     4501 cagaggaatt tccctgtctt tgattttaac tacctcagtt tttggtccca tccaggagga
     4561 actcattttc agaggacttc ttcaaggtgc ggtttttgac aattcttggt tagggcttgt
     4621 gctaacttcc tctctctttt ctttcatgca tggaccttct aatgtccctt cgtttatttt
     4681 ttatctactt gggggtttgt tgctgggctt tgcttataaa aagagtcaaa acctatgggt
     4741 ttctactcta gtccatatgc tttacaacag ttggccactc ttatattatt tataaaaatt
     4801 atgaaaaggt aagcagaaga cggtgcttac ctttttcaag ctataatgat acccaagcca
     4861 atccagaggc ttttctttga gaatcgggtt agagtggttg acgaataggc caaaaactag
     4921 tagaatagta aggaaacttt atacggagga aagaaatgga tttgggtgat aatgagctaa
     4981 cactgactcc catacctggg aaaagtggca aggcttatat gggtagctat cctgatggga
     5041 agcgcatctt tgtaaaaatg aacacctctc caatcctacc tggtctagct agagaacaaa
     5101 ttgctccaca attattatgg agtcgtcgtt tggcagatgg gcgtgatatg tgtgctcaag
     5161 aatggttgac aggcaagata ttgaccccct atgatatgaa tcgtaagcaa atcgtcaata
     5221 ttttaacccg tcttcatcgc tcacgtccgt tgatgacaca attgagtcgt ttgggctatg
     5281 ccatggaaac acctgtagat ttactacagt cttggcagga aacggctcca gatgctttgc
     5341 gtaaaaatca ttttatcagt gaagtgatgg ctgatttacg tcagactatt ccaggattta
     5401 gagaggacca tgcgaccatt gtccatggag atgtacgaca tagtaattgg attgagacag
     5461 atagtggctt gatttattta gtagattggg attcggttcg cttgaccgat cgcatgtttg
     5521 atgtggccca tatgctctgc cattatattt cagaacatca gtggaaggaa tggttgacct
     5581 actacggtta caagtacaat caaacggtat taagtaaatt gtattggtat ggtcaattgt
     5641 cttatttgag tcagatttcc aagtattata tgaaccaaga tttagaaaat gtcaatcggg
     5701 agattcatgg tttgcgtcat ttccgagaca agtatggaaa gagaagatga gagttagaaa
     5761 tcgtaaaggg gcaacagaat tactagaggc aaatccccag tatgtggtcc tcaatccctt
     5821 ggaagccaag gcaaaatggc gggacttgtt tggcaatgat aatcccattc atgtggaagt
     5881 tggaagtgga aagggtgcct ttgtttcagg tatggccaag caaaaccctg acatcaacta
     5941 tatcgggatt gatattcaaa agtctgtttt gagctacgct ttggacaagg tgcttgaagc
     6001 tggagtgtct aacatcaagc tcttgtgggt agatggttct gacttgactg actactttga
     6061 agacggtgag attgatcgct tgtatctgaa cttttcagat ccatggccga aaaaacgcca
     6121 tgaaaagcgt cgtttgacct acaagacctt tttggatacc ttcaaacgta tcttgcctga
     6181 aaatggagaa attcatttca agacggataa ccgtggcttg tttgagtaca gtttagtgag
     6241 cttttctcaa tatggcatga aactcaatgg tgtctggcta gatttgcatg ccagtgattt
     6301 tgaaggcaat gtcatgacag aatacgagca aaaattctca aacaaggggc aagttatcta
     6361 ccgagttgag gcagaatttt aagagatagc ctaaaattag gctgtacaag tgcttttgct
     6421 ttacataagt tggcaaacgt gctatactga tggtaagaat atgaaaagtg aggcggggaa
     6481 atatcttcgc ctcttgctta tgaggaggtg gacgcaatcg caacaatcgt agaattagtc
     6541 agagaagttg tagaacctgt catagaagct ccttttgaac tcgtggatat cgagtatgga
     6601 aagattggca gtgacatgat tctcagtatt tttgtagata aacccgaagg aattaccttg
     6661 aacgacacgg cagacttaac agaaatgatc agtcctgtcc tagacaccat caagccagat
     6721 cccttcccag aacaatattt cctagaaatt accagtccag gcttggaacg tcctttgaaa
     6781 accaaggatg ccgtcgctgg agcggttgga aaatacatcc atgtcgggct ctaccaagcc
     6841 atcgataagc aaaaggtctt tgaaggaacc ttgttggcct tcgaagagga cgagttgact
     6901 atggaatata tggacaagac gcgtaagaaa accgtccaaa ttccatacag tttagtatca
     6961 aaagcacgtt tagcagttaa attatagaaa aagaaaggat agcttttgag gattcaaaag
     7021 tgaagaaaac atgagtaaag aaatgctaga ggccttccgc attttggaag aagacaaggg
     7081 aatcaaaaaa gaagatatca tcgacgcagt agtagagtcg cttcgttccg cttatcgcag
     7141 acgctatggt cagtcagaca gcgtagctat tgacttcaac gaaaaaacag gtgactttac
     7201 agtttatact gtccgtgaag ttgttgatga agtatttgat agccgtttgg aaatcagctt
     7261 gaaagatgct cttgccatta attcagctta tgaacttgga gacaaaatca agtttgaaga
     7321 agcaccagct gagtttggtc gtgtagcagc ccaatctgcc aaacaaacca tcatggaaaa
     7381 aatgcgcaag caaacacgtg ccatcactta caatacttac aaagaacatg agcaagaaat
     7441 catgtctggt acagtagaac gctttgacaa ccgctttatc tatgtcaacc ttggtagcat
     7501 cgaagcccaa ttgtcaaaac aagaccaaat tcctggagaa gtttttgctt ctcatgatcg
     7561 tatcgaagtt tatgtttaca aggttgaaga caaccctcgt ggtgtgaacg tctttgttag
     7621 ccgtagccat ccagaaatga tcaaacgttt gatggagcaa gaaattccag aagtttatga
     7681 tggaactgtt gaaatcatga gcgtggctcg tgaagcaggt gaccgtacga aggttgctgt
     7741 tcgtagccac aatccaaacg tggatgctat cggtacaatc gttggacgtg gtggtgctaa
     7801 tatcaagaag attactagca aattccaccc agctcgttac gatgctaaaa atgaccgcat
     7861 ggtaccaatc gaagaaaata tcgatgttat cgagtgggta gcagatccag ctgaatttat
     7921 ctacaatgcc atcgctcctg ctgaggttga ccaagttatc tttgatgaaa acgacagcaa
     7981 acgtgccttg gtggttgttc cagataacaa gctttctctt gccattggtc gtcgtggaca
     8041 aaacgtgcgc ttggcggctc acttgactgg ttaccgtatc gatatcaagt ctgctagcga
     8101 atttgaagcc atggaagacg ctgcttcagt agagttggaa gtagaaaacg atactgtaga
     8161 agaataaaag ctgctagagg agggaaagat gaaaacaaga aaaatccctt tgcgcaagtc
     8221 tgttgtgtct aacgaagtga ttgataagcg tgatttgctc cgcattgtca agaacaagga
     8281 aggacaagtc tttattgatc ctacgggcaa ggccaatggc cgcggcgctt atatcaaact
     8341 agacaatgca gaagccctag aggcgaaaaa gaagaaggtc tttaaccgca gctttagcat
     8401 ggaagtggaa gaaagctttt atgacgagtt gatcgcttat gtggatcaca aagtgaaaag
     8461 aagagagttg ggacttgaat aagcaaaaga taagtaatct cttggggctt gctcagcgag
     8521 cagggcgcat catattgggt gaagaattgg tggtcaaggc cattcaagac ggcaaggcca
     8581 agttggtctt tctagctcat gatgctggac ccaatctgac caagaagatt caagataaaa
     8641 gtcattatta tcaagtagaa attgtaaccg tgttttcaac actggaatta agcatagcag
     8701 tcgggaaatc gagaaaggtt ttggctgtaa cagatgctgg atttacaaag aaaatgaggt
     8761 ctcttatgga atagaagagg aggacatgat ttgtctaaga aaagattgta cgaaatcgca
     8821 aaagaacttg gaaaagaaag taaagaagtt gtagcgcgtg caaaagagtt gggcttggat
     8881 gtgaaaagcc actcatcaag tgtggaagaa gctgtcgctg caaaaattgc tgccagcttt
     8941 aagcctgcag ctgctccgaa agtagaagca aaacctgcag caccaaaagt aagtgcagaa
     9001 aagaaagccg aaaaatctga gccagctaaa ccagctgtag ctaaggaaga ggcaaaaccg
     9061 gctgagccag ttgctccgaa aacagaaaaa gtagcagcga aaccgcaaag ccgtaatttc
     9121 aaggctgagc gtgaagcccg tgctaaagag caggcagaac gacgcaagca aaataagggc
     9181 aataaccgtg accaacaaca aaacggaaac cgtcagaaaa acgacggccg taatggtgga
     9241 aaacaaggtc aaagcaaccg cgacaatcgt cgctttaatg accaagctaa gaagcagcaa
     9301 ggtcagcaaa aacgtagaaa tgagcgccgt cagcaagagg acaaacgttc aaatcaagtg
     9361 gctccacgta ttgactttaa agcccgtgca gcagccctaa aagcagagca aaatgcagag
     9421 tacgctcgtt caagtgagga acgcttcaag cagtatcagg ctgctaaaga agccttggct
     9481 caagctaaca aacgcaagga accagaggaa atctttgaag aagcggctaa gttagctgaa
     9541 caagcacagc aagttcaagc agtggttgaa gtcgtccctg agaaaaaaga acctgcagtg
     9601 gatacacgtc gtaaaaaaca agctcgacca gacaaaaatc gtgacgatta tgatcatgaa
     9661 gaagatggtc ctagaaaaca acaaaagaat cgaagtagtc aaaatcaagt gagaaatcaa
     9721 aagaatagta actggaataa caacaaaaag aacaaaaaag gcaataacaa gaacaaccgt
     9781 aatcagactc caaaacctgt tacggagcgt aaattccatg aattgccaac agaatttgaa
     9841 tatacagatg gtatgaccgt tgcggaaatc gcaaaacgta tcaaacgtga accagctgaa
     9901 atcgttaaga aacttttcat gatgggtgtc atggccacac aaaaccaatc cttagatggg
     9961 gaaacaattg aactcctcat ggtggattac ggtatcgaag ccaaacaaaa ggttgaagtg
    10021 gataatgctg acatcgaacg tttctttgtc gaagatggtt atctcaatga agatgaattg
    10081 gttgagcgtc caccagttgt tactatcatg ggacatgttg accacggtaa aacaaccctt
    10141 ttggatactc ttcgtaactc acgtgttgcg acaggtgaag caggtggtat tactcagcat
    10201 atcggtgcct accaaatcgt ggaaaatggt aagaagatta ccttccttga tacaccagga
    10261 cacgcggcct ttacatcaat gcgtgcgcgt ggtgcttctg ttaccgatat tacgatcttg
    10321 gtcgtagcgg cagatgacgg ggttatgcct cagactattg aagccatcaa ccactcaaaa
    10381 gcagctaacg ttccaatcat cgtagccatt aacaagattg ataaaccagg tgctaaccca
    10441 gaacgcgtta tcggtgaatt ggcagagcat ggtgtgatgt caaccgcttg gggtggagat
    10501 tctgaatttg ttgaaatctc agctaaattc aaccaaaata tcgaagaatt gttggaaaca
    10561 gtccttcttg tagctgaaat ccaagaactc aaggcagacc caacagtgcg tgcaatcggt
    10621 acggttatcg aagcgcgctt ggataaagga aaaggtgcgg tcgcaaccct tcttgtacaa
    10681 caaggtacct tgaatgttca agacccaatc gttgtcggaa ataccttcgg tcgtgtccgt
    10741 gctatgacca acgaccttgg tcgtcgtgtt aaagttgctg gaccatcaac accagtctct
    10801 atcacaggtt tgaacgaagc accgatggcg ggtgaccact ttgccgttta cgaggatgaa
    10861 aaatctgcgc gtgcagcagg tgaagaacgt gccaaacgtg ccctcatgaa acaacgtcaa
    10921 gctacccaac gtgttagcct tgaaaacctc tttgataccc ttaaagctgg ggaactcaaa
    10981 tctgttaatg ttatcatcaa ggctgatgta caaggttctg ttgaagccct ttctgcctca
    11041 cttcaaaaga ttgacgtgga aggtgtcaaa gtgactatcg tccactcagc ggtcggtgct
    11101 atcaacgaat cagacgtgac ccttgccgaa gcttcaaatg cctttatcgt tggtttcaac
    11161 gtacgcccta caccacaagc tcgtcaacaa gcagaagctg acgatgtgga aatccgtctt
    11221 cacagcatta tctacaaggt tatcgaagag atggaagaag ctatgaaagg gatgcttgat
    11281 ccagaatttg aagaaaaagt tattggtgaa gcggttatcc gtgaaacctt caaggtgtct
    11341 aaagtgggaa ctatcggtgg atttatggtt atcaacggta aggttgcccg tgactctaaa
    11401 gtccgtgtta tccgtgatgg tgtcgttatc tatgatggtg aactcgcaag cttgaaacac
    11461 tataaagacg acgttaagga agttacaaac ggccgtgaag gtggattgat gatcgacggc
    11521 tacaatgata ttaagatgga tgatgtgatt gaggcgtatg tcatggaaga aatcaagaga
    11581 taagattttt tgctcctttc ttaggtggtg agggacgcaa gcaaaccgat ggtttcattg
    11641 cttatttttg agcctagggt ctcaaaaatc ccctgtgatg ggactgataa atcagttcca
    11701 tcactttcac cacggcgaaa gaagcagatg acttcaaatt gaacttcgtt tcaatttaaa
    11761 ctgaaaatca agaagtttaa aatagctagg tctgctggcc tagcttttgg ttcaaagtag
    11821 agaaaggaat atcatggtaa atcatttccg tatagatcgt gtgggcatgg aaatcaagcg
    11881 tgaagtcaat gagattttgc aaaagaaagt ccgtgatcca cgtgtccaag gtgtgaccat
    11941 cacagatgtt cagatgctgg gtgacttgtc tgttgccaag gtttattaca ccattttgag
    12001 taaccttgct tcggataacc aaaaagccca aatcgggctt gaaaaagcaa ctggtaccat
    12061 caaacgtgaa cttggtcgca atttgaaatt gtacaaaatc ccagatttga ccttcgtcaa
    12121 agacgagtcc atcgagtatg gaaacaagat tgacgagatg ctacgcaatc tggataagag
    12181 ctaaagaaga ggggttgccc ctcttttttg gtggaggaaa ataggttgaa tttgaaatgg
    12241 aaaaatattc ttttataata
//
LOCUS       DAVAGB010000052        12164 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVAGB010000052 DAVAGB010000000
VERSION     DAVAGB010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12164
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.053"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(92..1294)
                     /gene="rpsA"
                     /locus_tag="VQO19_001770"
     CDS             complement(92..1294)
                     /gene="rpsA"
                     /locus_tag="VQO19_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HET1349994.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(1456..1527)
                     /locus_tag="VQO19_001771"
     tRNA            complement(1456..1527)
                     /locus_tag="VQO19_001771"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1493..1495),aa:Gln,seq:ttg)
     gene            complement(1537..1617)
                     /locus_tag="VQO19_001772"
     tRNA            complement(1537..1617)
                     /locus_tag="VQO19_001772"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1581..1583),aa:Tyr,seq:gta)
     gene            complement(1667..1897)
                     /locus_tag="VQO19_001773"
     CDS             complement(1667..1897)
                     /locus_tag="VQO19_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HET1349995.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(2065..2709)
                     /gene="pcp"
                     /locus_tag="VQO19_001774"
     CDS             complement(2065..2709)
                     /gene="pcp"
                     /locus_tag="VQO19_001774"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET1349996.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(2724..3647)
                     /locus_tag="VQO19_001775"
     CDS             complement(2724..3647)
                     /locus_tag="VQO19_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HET1349997.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(3644..4333)
                     /locus_tag="VQO19_001776"
     CDS             complement(3644..4333)
                     /locus_tag="VQO19_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HET1349998.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(4398..5102)
                     /locus_tag="VQO19_001777"
     CDS             complement(4398..5102)
                     /locus_tag="VQO19_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET1349999.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            complement(5158..6180)
                     /locus_tag="VQO19_001778"
     CDS             complement(5158..6180)
                     /locus_tag="VQO19_001778"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HET1350000.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(6312..8783)
                     /gene="parC"
                     /locus_tag="VQO19_001779"
     CDS             complement(6312..8783)
                     /gene="parC"
                     /locus_tag="VQO19_001779"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HET1350001.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(9203..11146)
                     /gene="parE"
                     /locus_tag="VQO19_001780"
     CDS             complement(9203..11146)
                     /gene="parE"
                     /locus_tag="VQO19_001780"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HET1350002.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSNWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            11282..11923
                     /gene="plsY"
                     /locus_tag="VQO19_001781"
     CDS             11282..11923
                     /gene="plsY"
                     /locus_tag="VQO19_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HET1350003.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFITIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(11968..>12164)
                     /locus_tag="VQO19_001782"
     CDS             complement(11968..>12164)
                     /locus_tag="VQO19_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HET1350004.1"
                     /translation="DNGMMESFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNNK
                     RIKVKLKGLSPVQYRTKSFG"
BASE COUNT         3507 a         2756 c         2132 g         3769 t
ORIGIN      
        1 agcttagctg acttcaaccc actacagttg acaaagagcc agaaaaatcc cttgtttagt
       61 aaacaaagga ttttgtgaat tttcaatttg attaaagttc gatatcacca aacaaatcag
      121 ccattgaaaa tcctgtttgt gtttctggaa gttcgaaatc acgcttttct tgacgtcttg
      181 gacgacgtgg acgagcagca cgtttttctt ctttttgtcc ttcttcttgg gctggacgtt
      241 cttcaagagc tttaatagaa agtgacacgc gttctgcatc tgcgttaact tcaagaactt
      301 taacttgaac ttcttgacca actttaagag cttcttttgg attttcaatc cgtttgtgtg
      361 aaatttgtga tacgtgaaca agtccatcga tacctggcaa tacttcaaca aatgcaccga
      421 agtcagtcaa acgtttaact gttccttcta ctacatcacc tttagccaat ttttgctcaa
      481 cgccatccca tggtcctggt actgttgctt taagtgaaag tgatacacgt ccttcttctt
      541 cgttaagatc aaggattttc acttcaattt cttcaccaac agttacaact gattttggtg
      601 atacgttacg ttcatgtgac aattcagtca agtgaaccaa tccgtcaaca ccaccaaggt
      661 cgatgaaagc gccgaagctt gtgatacgag caactttacc agttacaaca tcaccaacag
      721 ccaatttacc gaatacttca gcgcgagctg ctgcagtagc tgcttcaaca acttcacgac
      781 gtgaaaggat gaagcggttt tctttagcgt taacttcttt gattttagta tcaaattctt
      841 gacctacaaa acgctcagcg ttacgtacga aacgagtatc caacattgaa gctgggataa
      901 atccacgaac accttcaaat tctactgaaa gtccaccttt aacggcacgc gttcctttaa
      961 cagtaacaac ttcttcttcg cgaccaacaa gtttgtccca tgctttgcga gcttcaaggc
     1021 gttttttaga tacaaggtat gtaactgtat cagtatcttt accaactact tgacgaagta
     1081 caagaacatc caatacttct cctactttaa caaagtcatt gatatctgca tcacgatcgt
     1141 ttgtcaattc gcgaagagtc aagacacctt caacaccagt tccagagatt gcaacgttag
     1201 cttgagtcgc atcaactgtc aatacttcag cactaacaac atcaccagtc tcaacttgac
     1261 taacgctatt tagcaaatct tcaaattcgt tcatctaaaa aatcctccaa caatcaagtt
     1321 tttcttaaac ttgacatact tataattttt ttcctaagca cccgcaagga catgttcata
     1381 tcattcacgt ctttcaatta taaaaataaa ataccctaag atattttgct ttctatcttg
     1441 attattacct aagaactggg gtagctggat tcgaaccaac gcatgaggga gtcaaagtcc
     1501 cttgccttac cgcttggcta taccccatta atgaaatgga gagagaggga ttcgaacccc
     1561 cgaacccgaa ggagcggatt tacagtccgc cgcgtttagc ctcttcgcta tctctcctac
     1621 aatcaacatg gactattata tcatgaaaat ttcaaaaaaa caagacttat tttgctaaat
     1681 tataattttc aatcaaaatt tccacagctt tttccaattt tttataaaaa ctatcgacat
     1741 tcccattctt tataatggca aattgtccgt ctaattcggc aatttctccg ataacttttt
     1801 taccgatagt caatgtataa ccttcaaaac tgtctttacc aacattaact ttggcatccg
     1861 ctacttgaat ttcgattttt ttatctttct tgctcatttc atacctctct tcactttttc
     1921 tattttacaa gaaaatccta aaactagcaa gaaaaaactc tatatcaggc ttctctgata
     1981 tagagtttta tgtaaacaac ctcaattgat ttagcatagt taatagttag taaacaagca
     2041 taattgacta tcctttttag gttatcagtg agtctcaccg cctactaact gcaaatcctt
     2101 atctttgtag tctacaatag cttcaatagc tacctctatg cctcttacaa tatcacatag
     2161 actcattcct gcagtattcg gcttatttac tacttgttcc atcatatatg gaatatgcat
     2221 gaaacctgct ctcatattag ggaatttttt atccactaaa taaagagctt ggtacatcaa
     2281 atgattgcaa acaaaggttc ctgcactatt ggatacaact gccggaagtc cctgtttttt
     2341 gatagcttgt accatcgctt tgataggtaa actactaaaa taggccgatg ctccatcaat
     2401 acgaatcggt gtatcaattg gttgattgcc ttcgttatca ggtatgcgag catcatcttg
     2461 attaatagcc actcgttcag gtgttaagcc ggtcctgccg cctgcttgtc caatacaaag
     2521 tacagcatct ggttgatatc gtaatatttc tgcctctaaa acttctgacg acttataaaa
     2581 aaccgttgga atttctaccc agcgaacttc agccccatta atctcagatg gtaataattt
     2641 tacagcctcc aaagctggat taatcttttc acctccaaaa ggattaaaac ctgtaaccaa
     2701 tattttcatt ttattttcct ttactaaaat gcgagaaagt acattaagaa tatgtgaata
     2761 acaatcatta ctagagcaac acctgcttga gcctttataa cgccattctg atctttcata
     2821 tccatcaatg ctgctggtag agcgttaaaa ttagcagcca ttggggtcaa taaggtccca
     2881 caataacctg ctgtcatggc aagagcacca gccacaattg gattagctcc cagagcaaat
     2941 acaaagggaa ctccaacacc tgctgtaata acggtgaatg ctgcaaaagc atttcccata
     3001 atcattgtga atagaaccat tccaagaaca taagccaaaa ctcctataaa gcgactatct
     3061 gaaggaacaa taccgctaat cagatgagag ataacatcac caacacctgc tacagtaaaa
     3121 atagccccca aagcccctaa taattgagga acaatcccac ttgttgaaac ttgctgagtc
     3181 attcgattat tttctgataa cagactctta gggtgactat tggtaatcac aagaacagaa
     3241 attgtagcaa acaaggcggc aaggctaatc gaaatcttgc taaattctgg aatcatttgc
     3301 gctaagacca acgcaagtat tgccatcagc ataactggaa taaaaatttt atttttcaac
     3361 ctgttagatt caatattggc tttcatttca tctaaggatg gcaaggttcc gatacggact
     3421 tgcttaaaca atgttaacag cgataatagg attacaataa taccaatact catatttggc
     3481 atataggaac cacctataaa cgtaatagac aatagagtcc aaaatgcaga tgtcccaagt
     3541 cgaactgggt ttgttttatc tttataacta caataggctg tatggagaaa ttgacaacca
     3601 atcacaatat aggtcaactc taatagttgc tttgccaact ctgtcatttt tgttctcctc
     3661 ccctagtctt ttttgatatc aattttttat caaataaata attgtaaatc cccactacaa
     3721 taagtgttat aacagcaaca ataatagatg tagaagcaat ccctgcataa ttgctttcat
     3781 agcctaactg atctaatgtt ccccctatca agaggactcc cccagcacct acaaacgtat
     3841 tttgagcaaa gaaatttcca aaattttcat tcgcagccgc acgcgctttt attgtctcat
     3901 cttcaacctc tgttaacttt ctacctaatt gagactctgc agctgcttct cccataggtt
     3961 gaaccaaagg tctgacaaac tgagggtgtc ctcctagacg aattgaaaag aaaccagcta
     4021 actctcgaat aaagaaataa actgtataga agtttccaac tgtcagacct ttaatctttc
     4081 gaatcaaatc gattgatcgt tgcttgagtc caaaggtttc tgacagcccc acaagaggca
     4141 aggtaaccat aaaaatcgtg agcactcgct gattgctaaa ttcttttccc aaaatctcca
     4201 aaaattcaac gagagaaaca cctgaaacta aagctgtaac caaaccagct aagactactg
     4261 ttgcaattgt atcaaatttt aaaataaaac ccacaacaat gattgctatt cctattaatc
     4321 taatccactc catatcaaac tcctttatat tcaaaatgac agtattttaa aaattttatc
     4381 aagatcaata ccattcctta tttaatgtat ttttctagtt ctttttggta tttgctattg
     4441 gattccaatt tttctttttg ccatttttta aaaacctcgt tatattcttt tgttgtaaca
     4501 atatcttttt gcaatttcat tcctttaaag atatatggtt cccccttaat accaacttgt
     4561 gagtatggtt ttgagaatgg tactacgtta cttacaactg gagaaccacc agatgaagct
     4621 gttggcatca ataatgaact atctgtcgac caagcttgag ctttggcata tttttcatat
     4681 ctcttctcta ggtcagtggt ctcagaaaca gcatcttcta acaatttctt atatttatcc
     4741 aaaccaggtt tagctacaac atccttatct tttcctttcg taatgccaag gtgtttcatg
     4801 gcagaaccag attttggatc cataatattc aagtaagacg ctggatcttg atagcttgga
     4861 gcccatcctg tactgttcaa atcatagtct ttttgagaag gagcaacatt gccgtattta
     4921 tcattttcca tcaaaccatc aataacattt ccaataacgt ctgtcctcga tgttcgagtc
     4981 gctatactgt agcccaatga tgctggatct actgcataga cataagaaaa tgttgtcggt
     5041 gcatctgctt ctttatcagt ttttccacaa gccactaaaa tagctgacgt gctcaggacc
     5101 actcctgctg ttaagagcca ctttttctat ttcataaaaa atctcctttg gtttatttta
     5161 atctactttt acaatccaac cttctggcgc ttcaatatcg ccaaactgaa tacccgtcaa
     5221 ttcattatat aatttacgcg tcacaggacc tacttctgtt tcactataga atacatggaa
     5281 atcatcacca tgttgaatac ctccaattgg agaaataacc gctgctgtac cacaggcacc
     5341 tgcctctaca aaacggtcaa gattatcaat tggaacatca ccctcaatag gagttaatcc
     5401 caagcgatgt tctgccaaat aaagcaagga atacttggta atagatggca agatagatgg
     5461 actcaatggt gttacaaatt cattatcagc tgtaattcca aagaaattag ctgatccgac
     5521 ttcttcaatc tttgtatgag ttgatgggtc cagatagata acatctgaga aatggcgtga
     5581 cttggccatt tttcctggta agagacttgc agcatagttt ccaccaacct tagccgcacc
     5641 tgtaccattt ggtgctgcac ggtcgtactc atcctgaatc aagaagttgg ttgggaccaa
     5701 accaccttta aagtaatttc caactggcat agcaaagatg gtgaaaatgt actcttctgc
     5761 cggttttacc ccgataatat ctccgacacc aatcaaaaga gggcgaagat ataaagttcc
     5821 acctattccg tatggtggta cgtattcttc attcgcacgg acaactgctt tacaagcttc
     5881 tacaaacatg tctgtcggaa cttgtggcat caagagacgg tcacatgtac gttgcaggcg
     5941 tttagcattt tcatcaggac ggaacagttg aacactgcca tccttagtac gataagcttt
     6001 caaaccttca aatgcttgtt gtccatagtg aagacttgga gaagactctg aaatatgcaa
     6061 agttgcatcc tctgtaagct ctccttgatc ccattgtcca tttttgaaat gagcaagata
     6121 gcgataaggt aatttcatat aggaaaaacc gaggttttcc caatcaatcg ttactgtcat
     6181 attccactcc ttattctaaa aacctatttc ttatattcta cactattttt ctaaaatagc
     6241 aagtatattt tgtaattttc agaaaatttc tccaataaaa accagctctt agaactgatt
     6301 cttcatttca cttatttatc ttcagtaact acttcctgaa gataagcgtc aaaaacttct
     6361 tcatctgaaa tcgtgtcaga aatgaagctt ccattgctag tgcgttctga caagttcaag
     6421 tcttgcaatc ggctttcata gattgttcct ttattggatt ggacaagtag agtttggtcg
     6481 ttcacatcca cttccgtact gaagaaatcg ccaacaaatc cttgctctgc aactgctcct
     6541 gccaagaaga cacgatgcgg tttgtttttc aactcacgca agacttgtaa tcctcgtttg
     6601 gcacggctgg ttgctagaat ttcctcaatg gaaacacgtt tcaagcttcc acgctgggtc
     6661 aagaggtaga aggacgaagt attacagata aagccagatt ggaggacatc atcttctttc
     6721 aaattcatag ccttgacacc tgctgcctta gcaccgacaa ccggaacctc ttcgatattg
     6781 aaacgcaggg cataaccatt ttgactaacc aagacaacat catctagttt aatcggagcc
     6841 actgctacaa tctgatctgt atcgtctttg agcttagcat acttgacaga cttagatcta
     6901 taggtccgcc atggagtgaa ttcttttcgc tctacccgtt tgatttgacc aaggcgagtc
     6961 actgcaaagt aggttgtcgc atcgtcaaac tgatccagta cttccacata aaggatttct
     7021 tcattcgttt caaagtttgt gatggtttgg ctcagatgct ctccgatgtc cttccaacga
     7081 atatctgcca actcatggat tggtctgtag atgacatttc caagacttgt gaacatcaag
     7141 aggtgctggg ttgtcttggc agattgaaca aaaatcaaac ggtcatcatc acgcttgcca
     7201 atttcttcca aggtggaagc cgcaaaggaa cgtggactgg tacgcttgat gtaacctgcc
     7261 ttggtcacgc tgacgtaggt atcttcctca gcgataagac tagctgtatc aatctcaatt
     7321 gctttcgcag tgtcttctaa agaactcaaa cgaggagttg caaatttctt cttgacctca
     7381 cgaagttctt tcttcatgag attgtacata gtcctttcat caccgataat agccgccagc
     7441 atagcaatct tctcacgaag ctctgcttct tcttcctgca agacaaccac atcggtattg
     7501 gtcaaacggt acagttgcaa agttacgata gcctcagcct gttcttccgt aaaatcatag
     7561 ctaactttga ggttttcctt ggcgtccgcc ttattctcag aagcacggat aagagcaatg
     7621 acttcatcca aaatcgaaat cacacgaatc aaaccttcga cgatatggag acgtttctca
     7681 gccttttctt tgtcaaagcg tgaacgcgcc aaaatcactt ctcgacggtg agcgatgtag
     7741 ctagacagga ttggaacaat cccaacctga cgaggtgtga aattgtcaat cgccaccata
     7801 ttaaagttgt agttgatttg taggtcggtg tacttaaata agtagttgag aacaagctca
     7861 gtattagcgt ctttcttaag ttcgatagcg atacgaagac catcacggtc agactcatca
     7921 cgaacctcag caatcccagc taccttgtta ttaacacgaa catcatcgat tttcttaact
     7981 agattggcct tattgatttc ataaggaatc tcagtaataa cgatttgttc cttaccacct
     8041 tttagctttt caatttcagt cttggaacga acaaccacgc gccctttccc agtctcataa
     8101 gctttcttga tttcatcacg accctgaata atagcccctg tagggaagtc tggtccaggc
     8161 aagaattcca tgagtttatc aatctttgca gttgggtggt caatcatgta aactgcagca
     8221 tctatgacct cagctaaatt atggggagga atgtctgtgg cataaccagc cgaaatccca
     8281 gtcgaaccat tgaccaagag gtttggaaag gctgctggca agaccgttgg ttctttctcc
     8341 gtatcgtcaa agttccatgc aaaaggaact gtatttttct cgatatcctg aagaaggtaa
     8401 cctgcaattt cagacaaacg tgcctcagta taacgcatag ccgcaggagg atctccgtcc
     8461 atagaaccgt tattaccgtg catttcaact agaatctcac gatttttcca gttctgtgac
     8521 atacgaacca tggcatcata gatagaagaa tccccgtgtg ggtggaaatt ccccatgatg
     8581 ttcccgactg acttggccga cttacggtag ctcttgtcaa aagtattgct atccttattc
     8641 atagaataaa gaatacggcg ctgaaccggc ttcaacccat cacgaatatc tggcaaagcc
     8701 cggtcttgaa taatgtactt ggagtagcga ccaaagcgct ctcccatgat gtcctccagg
     8761 gacatgtttt gaatgttaga cataagatac aaagcccata aaataccaag tgaaaataga
     8821 aaattcttga agtaagcaaa ctcacaagag aatttatctt tttcacacag tatctagggc
     8881 gtgttcaact cctttcaaag aatgtagagt aggtttttat gcagtaaaag atattttacg
     8941 ggaattcctc ccgtgttcag ttacgataag taaccaaact atcctgtttg tatttttcaa
     9001 tatgaaaatc tggttttcca aaattagtct tagtttgtgt cttagccgct cccttaagcg
     9061 cctctttgag ataagcactc atagcagatt cttcattaat aatcctgcaa ttttttcaaa
     9121 ccaagatttt caaactgctt tttcacatag tcattcacat ccgactctaa tttccagttt
     9181 actaacatat tattttcttt cattaaaaca ctgtcgcttc ttctagcgta aacttgacat
     9241 tatcttcaat ccatttacgg cgtggttcta ccttatctcc catgagaaca ttgacgcggc
     9301 gttcggcgcg cgctaaatct tcaattgtga cacggatgag ggtacgtgtt tctgggttca
     9361 tggttgtttc ccagagctgg tccgcattca tctcaccaag tcctttgtat cgttggaggg
     9421 tagcgccttt accgaactgt ttacggagtt cttctagttc tccgtccgtc caagcgtagg
     9481 ccacttcttc tttcttgcct ttacctttgg acatcttata aagaggtggg agggcaatat
     9541 agacatgacc tgcctcgact agcggacgca tgtaacggta gaaaaatgtc aagagcaagg
     9601 tctggatatg ggcaccgtcg gtatccgcat cggtcatgat aatgatctta tcatagttgg
     9661 catcttcaat agagaagtct gctccaacac ccgcaccaat ggtataaatc atggtattaa
     9721 tctcttcatt tttgaggata tccgccatct tggccttggc tgtattgaca accttaccac
     9781 gaagaggtag aatagcctgg aacttgcggt cacgaccttg tttggcagaa ccaccggcag
     9841 agtccccctc aactagatag agttcattct tagcaggatt cttagattgg gctggggtca
     9901 atttcccaga caacaagccc ttatctttct tgtttttctt cccatttcgg ctctcatcac
     9961 gcgccttacg tgctgcttca cgagcatcac gggccttgat agccttgcgg atgaggttag
    10021 aagctaattc cccattttcc ataaggaaaa aggtcaactt atcagccact attccatcca
    10081 caactgggcg agctaggggg cttcctagtt tatccttggt ctgtccttca aactgcaagt
    10141 gttcttcagg aactaagata gaaagaacgg ccgctagtcc ctcacgatag tctgaacctt
    10201 caaggttttt atctttttcc ttgagaagac ctgttttacg tgcatagtca ttcatgacct
    10261 tggtaatggc agacttgagt cctgtctcgt gcgttccacc gtccttggtg cgaacgttat
    10321 tgacaaagga tagaatgtta tctgagaatc cgtcattgta ctggagggct acttccactt
    10381 gaaaaccatt gtcttcccct tcaaagtaaa gaactggcgt caagatttcc ttatcttcgt
    10441 tgagataaga aacaaaatct tgtactccat tctcatagtg gaactcaatc gcttcatctg
    10501 ttcgcttgtc cgttaaagac aaggtcacat ttttcaagag aaaggctgat tcattaaggc
    10561 gctctgaaat ggtattgtac ttgaaatctg tcgtagaaaa gatagtcgcg tcaggcataa
    10621 aagtaacttt ggtgcctgtt ttagacttgg gtgctgtacc gattttcttc aaagtcgtga
    10681 caggttttcc accattttcg aaacgttgct tgtaaactgc accatcacgg gtaatttcaa
    10741 cttctaacca gttagaaagg gcgttaacaa cggaagaacc cactccgtga agtccacctg
    10801 atgtcttata gccaccttga ccgaatttcc ctccggcatg aagaatggta aagataacct
    10861 caacagttgg aattcccata gcgtgcatac ctgtcggcat cccacgtcca tggtcttgaa
    10921 ccgttagact accgtcttta ttgatagtta catcaatacg atcaccaaac ccagacaagg
    10981 cttcatcgac tgcattatca acgatttccc aaactaggtg atgaagacca gcgccatcgg
    11041 tcgatccaat atacatccct ggacgttttc ggaccgcatc caacccttct agcacctgaa
    11101 tagcatcatc attataattg ttaatattga tttccttttt tgacacaagg aacctcctat
    11161 tcgttcatct ttactattct acaggttttc caaggatttt gcaaaatttt tctttctccg
    11221 atgtgacaat ttcagcagag attctctgct tttctttccc aattcatgat ataataggag
    11281 tatgattaca atagttttat taatcctagc ctatctgctg ggttcgattc catctggtct
    11341 ctggattgga caagtattct ttcaaatcaa tctacgcgag catggttctg gtaacactgg
    11401 aacgaccaac accttccgca ttttaggtaa gaaagctggt atggcaacct ttgtgattga
    11461 ctttttcaaa ggaaccctag caacgctgct tccgattatt tttcatctac aaggcgtttc
    11521 tcctctcatc tttggacttt tggctgttat cggccatacc ttccctatct ttgcaggatt
    11581 taaaggtggt aaggctgtcg caaccagtgc tggagtgatt ttcggatttg cgcctatctt
    11641 ctgtctctac cttgcgatta tcttctttgg agctctctat cttggcagta tgatttcatt
    11701 gtctagtgtc acagcatcga ttgcggctgt tatcggggtt ctgctctttc cactttttgg
    11761 ttttatcctg agtaactatg actctctctt catcactatt atcttagcac ttgctagttt
    11821 gattatcatt cgtcataagg acaatatagc tcgtatcaaa aataaaactg aaaatttggt
    11881 cccttgggga ttgaacttaa cccatcaaga tcctaaaaaa taaaatgcca gttctgtgaa
    11941 ctgcacccca aaagttagac aattaattta tccgaaggat ttagttctgt attgcacagg
    12001 gctaagtcct tttagtttta ccttaattcg tttattgttg tagtaatcaa tatagtccac
    12061 aatagcttgt tcaaggtttt ctaaagatct aaagttcttc tcataaccat aaaacatctc
    12121 cgatttcaaa atgccaaaga aagattccat catgccgttg tctg
//
LOCUS       DAVAGB010000053        11849 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVAGB010000053 DAVAGB010000000
VERSION     DAVAGB010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11849
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.054"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            176..832
                     /locus_tag="VQO19_001783"
     CDS             176..832
                     /locus_tag="VQO19_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HET1350005.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTDLGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQMMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            822..1145
                     /locus_tag="VQO19_001784"
     CDS             822..1145
                     /locus_tag="VQO19_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HET1350006.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            1250..2080
                     /locus_tag="VQO19_001785"
     CDS             1250..2080
                     /locus_tag="VQO19_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET1350007.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2234..3088
                     /locus_tag="VQO19_001786"
     CDS             2234..3088
                     /locus_tag="VQO19_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HET1350008.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSTNKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            3188..4561
                     /locus_tag="VQO19_001787"
     CDS             3188..4561
                     /locus_tag="VQO19_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HET1350009.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEDRMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4554..5615
                     /locus_tag="VQO19_001788"
     CDS             4554..5615
                     /locus_tag="VQO19_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HET1350010.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5617..6309
                     /locus_tag="VQO19_001789"
     CDS             5617..6309
                     /locus_tag="VQO19_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET1350011.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6339..6908)
                     /locus_tag="VQO19_001790"
     CDS             complement(6339..6908)
                     /locus_tag="VQO19_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET1350012.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIAFFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVTPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7043..7657
                     /locus_tag="VQO19_001791"
     CDS             7043..7657
                     /locus_tag="VQO19_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET1350013.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7659..9305
                     /locus_tag="VQO19_001792"
     CDS             7659..9305
                     /locus_tag="VQO19_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET1350014.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHMGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9317..10603
                     /locus_tag="VQO19_001793"
     CDS             9317..10603
                     /locus_tag="VQO19_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET1350015.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10655..11188
                     /locus_tag="VQO19_001794"
     CDS             10655..11188
                     /locus_tag="VQO19_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET1350016.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            11266..11736
                     /gene="nrdI"
                     /locus_tag="VQO19_001795"
     CDS             11266..11736
                     /gene="nrdI"
                     /locus_tag="VQO19_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HET1350017.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
BASE COUNT         3411 a         2217 c         2739 g         3482 t
ORIGIN      
        1 ctcaaaacgg tgttttgagc tgacttcgtc agttctatcc acaacctcaa aacggtgttt
       61 tgagcaacct gcggctagtt tcctagtttg ctctttgatt ttcattgagt attattaaga
      121 caatatgagg agaaagatga aagaaaaagg attttaggag ggggcgcagg cagccatgcc
      181 aacggctctt ggctatgtca gtatcggcct ggcctgtggg actatcggtg cgccctatgt
      241 gacacctgtt gagatgggct tgatgagtct ctttgtttat gctgggagtg cccagtttgc
      301 catgttggca ctgattgtgg ttcaagctcc tgtggcagct attgctatga cggtttttct
      361 aatcaacttg cgtctctttt tgttgagttt acacgcatcg acttatttcc gtcataccag
      421 tctttggtac aatatcggta tgtctagtat cttgacagat gagacctatg gcgttttgat
      481 gggtgaattg gcccatacag acaaggtaaa tcctatgtgg atgcacggaa acaatcttaa
      541 cagctatgtg gcttggtttg tggggacagt agtcggaacg gatctgggtg gcctgctacc
      601 aaatccagaa atctttggct tggattttgc cctggttggg atgtttattg gtatttttgc
      661 ttcgcaattt cagatgatgc aaagacggat tcctgtccgc aatctgctca ttatcctagc
      721 agttgttgcg gtgtccttct ttttgctctt gacagtggtg tctcagtcac tagctgttct
      781 gtttgcgacg ctacttggtt gtagcatggg ggtggtttta gatggtcagt aagtatcttt
      841 tattagcagt tattttctct ggcttggtga cttggattct ccgtatgatt cccttcatct
      901 tagtcaagta taagggcttg cctgcaatcg ttgagcgttt tttgaagttc ttgcccgttt
      961 ccattatctt tgccttgatt ctttcaagcg tagtgacagg taaggttggg agccttcctc
     1021 aaattaaatg gctagacttc ttagccgtct ttccaacagc ttgggtagcc tttcgctacc
     1081 gcaatctagt cggaacagtt ctctttggag tggtcttgat tgccatcttg cgtttggtct
     1141 tttaaattac ccataaaaaa aaacttatca cagagataga tatcatataa tggcgtaaat
     1201 gctctttttc tgttaagatt ataaggtatt ctattttgga ggaaatgaca tgaaaaaaat
     1261 cgttaaatac tcatctcttg ctgccctagg acttgttgct gcaggtgtgc ttgcggcttg
     1321 ctcagggggt gctaagaaag aaggagaagc agctagcaag aaagaaatca tcgttgcaac
     1381 caatggatca ccaaggccat ttatctatga agaaaatggc gaattgactg gttacgagat
     1441 tgaagtcgtt cgcgctatct ttaaagattc tgacaaatat gatgtcaagt ttgaaaagac
     1501 agaatggtca ggtgtctttg ctggtcttga cgctgaccgt tacaatatgg ctgtcaacaa
     1561 tcttagctac actaaagaac gtgcggagaa atacctctat gccgcaccaa ttgcccaaaa
     1621 tcctaatgtc cttgtcgtga agaaagatga ctctagtatc aagtctctcg atgatatcgg
     1681 tggaaaatcg acggaagtcg ttcaagccac tacatcagct aagcagttag aagcatacaa
     1741 tgctgaacac acggacaacc caactatcct taactatact aaggcagact tccaacaaat
     1801 catggtacgt ttgagcgatg gacaatttga ctacaagatt tttgataaaa tcggtgttga
     1861 aacagtgatc aagaaccaag gtttggacaa cttgaaagtt atcgaacttc caagcgacca
     1921 acaaccgtac gtttacccac ttcttgctca aggtcaagat gagttgaaat catttgtaga
     1981 caaacgcatc aaagaacttt ataaagatgg aactcttgaa aaattgtcta aacaattctt
     2041 cggagacact tatctaccgg cagaagctga tattaaataa tttcttgaaa tcatccattc
     2101 tgagtaaggt gggtggtttc tcagttttta gggatatagt tttaaactat atatctgatt
     2161 atctaataac aatttgtgaa atcaaacaaa ttgtgagata ctagtacggt attattttta
     2221 aggagaaaga atcatgaaaa tcaaaaaatg gcttggccta gcagcccttg ctacagtcgc
     2281 aggtttggct cttgcagctt gcggaaactc agaaaagaaa gcagacaatg caacaactat
     2341 caaaatcgca actgttaacc gtagcggttc tgaagaaaaa cgttgggaca aaatccaaga
     2401 attggttaaa aaagacggaa ttaccttgga atttacagag ttcacagact actcacaacc
     2461 aaacaaggca actgctgatg gcgaagtaga tttgaacgct ttccaacact ataacttctt
     2521 gaacaactgg aacaaagaaa acggaaaaga ccttgtagcg attgcagata cttacatctc
     2581 tccaatccgc ctttactcag gtttgaatgg aagtaccaac aagtacacta aagtagaaga
     2641 catcccagca aacggagaaa tcgctgtacc gaatgacgct acaaacgaaa gccgtgcgct
     2701 ttacttgctt caatcagctg gcttgattaa attggatgtt tctggaactg ctcttgcaac
     2761 agttgccaac atcaaagaaa atccaaagaa cttgaaaatc actgaattgg acgctagcca
     2821 aacagctcgt tcattgtcat cagttgacgc tgccgttgta aacaatacct tcgttacaga
     2881 agcaaaattg gactacaaga aagcactttt caaagaacaa gctgatgaaa actcaaaaca
     2941 atggtacaac atcattgttg caaaaaaaga ttgggaaaca tcacctaagg ctgatgctat
     3001 caagaaagta atcgcagctt accacacaga tgacgtgaaa aaagttatcg aagaatcatc
     3061 agatggtttg gatcaaccag tttggtaata agaaacaggg aggtgggaga gaaaattcca
     3121 cctcttgctt ttgtatagag tatagattgt aaagaagact attcgttcat agaaaggtag
     3181 agagaatatg gtttttccta gcgaacaaga acagattgaa aaatttgaaa aggatcatgt
     3241 agtccaacat tattttgagg ttttgcgtac cttgatttct aagaaatcag tctttgccca
     3301 gcaggttgga ctcaaggaag tcgcaaatta tctgggtgag attttcaagc gtgttggagc
     3361 tgaagtggag attgatgaga gctatacagc gccctttgtc atggcacatt tcaagagttc
     3421 gcgtccagat gccaagacct tgattttcta taaccactat gacactgtgc cagcggatgg
     3481 ggatcaggtc tggacagagg atccttttac gctttcggtc cgcaatggct tcatgtatgg
     3541 gcgtggggtt gatgacgaca agggtcatat cacagctcgc ttgagtgctt tgagaaaata
     3601 tatgcagcac catgatgatt tacctgtcaa tatcagcttt atcatggagg gagcggagga
     3661 atcggcttca acagacctag ataagtattt ggaaaagcat gcagacaaac tccgtggggc
     3721 ggatttgttg gtctgggaac aagggaccaa aaatgccttg gaacagctgg aaatttctgg
     3781 tggcaataag gggattgtga cctttgatgc caaggtaaaa agcgctgatg tggatatcca
     3841 ctcgagttat ggtggtgttg tggaatcagc tccttggtat ctcctccaag ccttacagtc
     3901 tcttcgtgct gcggatggcc gtatcttggt tgaaggcttg tacgaagaag tacaagagcc
     3961 taatgaacga gaaatggcct tgctagaaac ttatggtcaa cgaaacccag aggaagttag
     4021 tcggatttat ggattggagt tgcctctctt acaggaggat cggatggcct ttctaaaacg
     4081 tttctttttc gagccagcgc ttaatatcga aggaatccag tctggttatc aaggtcaggg
     4141 tgttaagact attttacctg cagaagccag tgccaagcta gaggttcgtc tggttccggg
     4201 cctagaaccg catgatgttc tggaaaaaat tcggaaacag ctagacaaaa atggctttga
     4261 taaggtagaa ttatactata ccttgggaga gatgagctat cgaagcgata tgagcgcacc
     4321 agccattctc aatgtgatcg agttggccaa gaaattctat ccacagggcg tttcagtctt
     4381 gccgacgaca gcggggacag gacctatgca tacggtcttt gatgccctag aggtaccaat
     4441 ggttgcattc ggtctaggaa atgccaatag ccgagaccac ggtggagatg aaaatgtgcg
     4501 aatcgctgat tattacaccc atatcgaatt agtagaggag ctgattagaa gctatgagta
     4561 gagatattat caagttagat cagatcgatg tgacttttca ccaaaagaag agaaccatca
     4621 cagcggttaa ggatgtgacc attcacatcc aagaagggga tatctacgga atcgttggat
     4681 attctggagc agggaaatca acccttgtac gggtgattaa cctcttgcaa aaaccatctg
     4741 cagggaaaat taccattgac gatgatgtga tttttgatgg taaggtcacc ttgacggcag
     4801 agcagttgcg tcgtaaacgt caagatatcg ggatgatttt ccagcatttt aacctgatga
     4861 gtcaaaagac agcagaggag aatgtagcct ttgcccttaa acactctgga ctcagcaagg
     4921 aagaaaagaa ggctaaagta gctaagttgt tggacttggt tggtttggca gatcgtgctg
     4981 aaaactaccc ttcacaacta tctggagggc aaaaacagcg tgtggcaatt gcgcgtgcct
     5041 tggccaatga tccaaaaatc ttgatttcag acgagtcaac ttctgccctt gaccctaaga
     5101 caaccaagca gattttggcc ttgttgcaag atttgaacca aaaattagga ttgacagttg
     5161 tcttgattac gcatgaaatg cagattgtca aagacattgc caaccgtgtg gcggttatgc
     5221 aggatgggca tttgattgaa gagggaagtg tccttgaaat cttctcaaac cctaaacaac
     5281 ctttgactca agactttatc tcaacagcca caggtattga cgaagccatg gtcaaaatcg
     5341 agaagcaaga aatcgtggaa cacttgtctg aaaacagtct cttggtgcaa ctcaagtacg
     5401 ctggagcttc aacagacgag ccacttttga atgaattgta caagcattac caagtaatgg
     5461 ctaatattct ctatgggaat atcgaaattc tcgatggtac tcctgttgga gaattggtgg
     5521 tggttttgtc aggtgaaaaa gcagcgttgg caggtgccca agaagccatt cgtcaagcag
     5581 gtgtacaact aaaagtattg aagggagtac agtaagatgg aatcattgat tcaaacctat
     5641 ttaccaaatg tctataaaat gggttgggct ggtcaggcag gctggggaac ggctatctac
     5701 ttaactcttt atatgacagt tctttccttc attatcggag gcttcttggg gctagtggca
     5761 ggtctctttc tcgtcttgac agcgccaggt ggtgtcttgg agaataaagt cgtattctgg
     5821 attttagaca aaattacctc aatttttcgt gcggttccct ttatcatcct cttggcaatc
     5881 ttgtcaccac tttctcactt gattgttaaa acaagtatcg ggccaaatgc agcccttgtc
     5941 ccactttctt ttgcagtctt tgccttcttt gcccgtcagg tgcaggttgt cttggctgaa
     6001 ttggatggcg gtgtcattga ggcggctcaa gcgagcggag cgactttctg ggacatcgtg
     6061 ggtgtttacc tatcagaagg tcttccagat ttgatccgtg tgacgactgt gaccttgatt
     6121 tcccttgttg gggaaacagc tatggccggt gcggttggag ctggtggtat cggtaacgta
     6181 gccatcgctt atggatttaa ccgctacaat cacgatgtga ccatcttggc aaccatcatt
     6241 atcattttga ttatctttgc aatccaattc ttgggagatt tcttgactaa gaaattgagc
     6301 cataaataaa aaagagccgt gtggctcttt ttaactgatc agattttctg ggcaaatttt
     6361 ttactcaagg cttgtccaat caaggcaccc actagggctc cgatgacaat acttgcgata
     6421 aatagaagga cagttccagg gtttggagtg accatgatac ggtcgatata ttcttgggat
     6481 tttcctcttg ccagaagagt agccatatag gctttgggcg caatccacat aagcaagatt
     6541 ggtcctgttg tactaaaggc gaaaataatg aaagaaagga agttctttgt tttgtccttg
     6601 tattttccta aatgagctac ttcatctgct aggaggccac agataattcc aggaaggaag
     6661 gaaccagcac cgtgtttagt tcccaagaaa aagaaggcaa tgacaaggcc gatagtggta
     6721 atggctccaa agcgcggaac ttttgcgact aggatcatat agacgctacc gccgacaagg
     6781 gcagtaaagg caggcgcata aaacatgttt ccagtttggt caaagagatt gcccaaaagg
     6841 acaccaatcc ccatgcagag gaagtaaaga actgcaaaaa gcagtgtagt taagatagat
     6901 tttttcatga attgtctcct gataattttt tcacaattct cattgtacca cggtttggtg
     6961 ggattgtaaa tggatactag aagtttttga aaacgcttga aatatgatat aatggtttca
     7021 tagttatttt taggggaata tcatgggtag atttttagac tttgtcttta atcgtttctt
     7081 tttagggatg attgcgacag ccttcttttg gctattaact ttagcaggag ggattatcct
     7141 tggtctagcg ccggctagtg ccaccttgat gagcttatat gcagaacatg gttatagctt
     7201 tcgggaatac agtttgaagg aggcttggtc tctttacaag caaaattttg tctcaagcaa
     7261 cctgattttc tatagctttt taggtgtggg tctagttttg acctatggtt tgtatctctt
     7321 ggtgcaattg cctcatcaga ccattgttca tttgattgcg acccttttga atgtcctagt
     7381 agttgccctg atctttttgg cttatacagt atctttaaaa ttacaagttt attttgcctt
     7441 gtcctatcga aatagtctca aattatcctt gattggcatc tttatgagtc tagcagctgt
     7501 ggccaaggtt ctccttggga ctgtgctact tgtagcaatt ggttactata tgcctgccct
     7561 gctatttttt gtaggaattg ggatgtggca tttctttatc agtgatatgt tggaacctgt
     7621 ctatgaaatc atccatgaaa aattggcgac aaaatagaat gaagcagttt tggctacata
     7681 cgcttctaag aacctatagt tcagtgatga tcattatcat tgcgagtttt gcaatcttac
     7741 tctcttacgc tgactgggat tcacgtgaaa aggaagccca gagagtagcc cagcgtgtaa
     7801 ctgctagaac agtgagtgaa attgaatatt accatagaga gtcaacccag atagctcagg
     7861 ctttagttga aaatcaagct cgtatcgagg gaatctataa atactttagc cttagcatgc
     7921 cagactattt ttactggcaa ttagagcgga aagcttcgcc ttatatatca gtctctctgt
     7981 atgaaaatgt tgatgacctc tatgttcgaa atgattttgt aactggggtg gccattgctt
     8041 ttcaagatta caaggaagtc tatgtttcta ctaaagacaa acgtagtgga gaaaaaatca
     8101 gggctgagga tttcaaacca gcaggaaata gttttgccat tccagtgtca gatccagtgt
     8161 cagatcaaga cttaggagtg atttacatct ccttggatcc tgctgtttta taccatgcca
     8221 ttgataatac tagaggtcat actccgatgg cagtaacagt gacctcacct tttgatacgg
     8281 agatttttca tatgggtgag acagttgata aggagagtga aaattggcta gttggcttaa
     8341 cttctcatgg ttatcaggtt caggtggcag ttcccaaaaa ctttgtttta caaggaacgg
     8401 tgaccagctc tgctttgatt gtgggcttga gccttctctt tattgtcatt ctttatctga
     8461 ctttgaggca gacctttgct aattatcaaa agcaggtagt ggatttggtg gattccatcc
     8521 aagctattgc ccaaggacaa gaaggtcttc gcattgatac gcttgaaaag gatcaggaat
     8581 tgctcctaat cgcggagacg accaatgata tgttggatcg attggaaaag aatatccatg
     8641 atatttacca gttagaactc agtcaaaaag atgccaatat gcgggccttg caggcgcaaa
     8701 tcaaccctca cttcatgtat aatacgctgg agttcttgcg tatgtacgca gtcatgcaga
     8761 gtcaagatga gttggcagat atcatttatg aattcagtag tctcttgcgt aacaatattt
     8821 ccgacgaaag agagaccctc ctcaaacagg aattagaatt ttgccgtaaa tacagctatc
     8881 tctgcatggt tcgctatccc aagtccattg cctatggttt caagatagat ccagagttag
     8941 agaatatgaa gattcccaag tttaccttgc aaccgctggt agaaaactat ttcgcgcatg
     9001 gtgttgacca caggcggaca gataatgtga ttagcatcaa ggctcttaaa caggatgggt
     9061 ttgtggaaat tttggtggtc gataatggta gaggaatgtc ggctgaaaag ttggcaaata
     9121 tccgagaaaa attaagtcag aaatattttg aacaccaagc cagctacagt gatcaaaggc
     9181 agtctatcgg gattgtcaat gtacacgagc gttttgtgct ctattttgga gaccgctatg
     9241 ccattactat agagtctgca gagcaagccg gtgttcagta tcgtattaca attcaagatg
     9301 agtagaaagg gagaaaatgt ataaagtatt attagtagat gatgagtaca tggtgacaga
     9361 aggtctgaag cgtttgattc cctttgataa gtgggatatg gaggtcgtcg caacagccag
     9421 tcatgccgat gaagctctag aatatgttca ggaaaatcct gtcgatgtca tcatttccga
     9481 tgtcaatatg ccagacaaaa cagggcttga tatgattcgg gagatgaaag agatcttacc
     9541 agatgctgcc tatatcctgc tctcaggtta tcaggagttt gattatgtaa aaagagcaat
     9601 gaaccttagt gtggtggact atttggtcaa gcctgttgat aaggtagagc tgggaaatct
     9661 gctggagaag attgcaggtc agctcggcga gagagggaag aaaagtcaga ctcttagtca
     9721 agaattagac gaggctggat ttgttagtta tttaggggat aaggagaatt ggtggatagg
     9781 tctatccaag gaaaaacaag gttccttcac cattccctac tatgtcttgg gccaagactg
     9841 gcagattttc atttctgacc aacccctaga tggtttagtc gttacacctt ttgaagctcc
     9901 ttatcaagaa cactttgaac gctggaagct gaatgctgag aaaaccctct tttacggttc
     9961 tgtaaatctg cagcagtctg agagtctctt tgcctattac gaaccgattt atagggttat
    10021 tattcaggga aatctcaatc aaatcgtaga agagttaaat ctcttggaga aggtagttct
    10081 tgaaaatacg ccgcgtgttc cgattactaa acagcttttt attcagtttg tcatggatgt
    10141 tttccattta tttgaacatc tcaaagctga tgacctgaca gacatcgtca aaaccattca
    10201 tgctattcaa tccttcgatg aattggttcc ttatatcaag gaaactctga gcagcttttt
    10261 cggtcaatac cgtatgaatg aaaatgtggt cagtgtgctg gaagtcattg gtcgtgatta
    10321 ccaaaaagag ctttccctca aggatatcag taaggctctc tttatcaatc ctgtctatct
    10381 agggcagttg attaagcgtg aaaccgattc gacttttgca gagttactaa acaaacaacg
    10441 tattaaggct gcccaacaac ttttgctttc aactagtgac agcatcgaag atatttgtta
    10501 tgctgttggt tacagtaacc ttggatattt ctataaagtt ttccgaaaat tgtgcggaaa
    10561 atcgccaaaa gcctaccgaa aacaggtaga aactatacta taagatttgt attcctttac
    10621 aaaaggtgct ataatattat caggaggtcc tatcatgaaa aagaaaccaa tttatctatg
    10681 ggtcttgcta atcttgtctg cccttatttc agttccgtct ctgtttggaa ttgtgagtcc
    10741 cttgcctagt aaagaagccc ttcgtgctgc tcagaaacaa gttgcagggg tcaatgctca
    10801 gcaattagaa gaccagctta attataccta tagagtagca gaagcatctc attctatttt
    10861 taatgttgct ttgattgtgc tatctactat tttagtggtc gtagcgattg tcttccttgt
    10921 tcgtaaaaat ttgcaatatg caaactatac ttacgttggc tatgttttgt tagctattat
    10981 tggttcgatt tatggctatg ttggtttaca agacgctgtg cagttggttc aagatgagag
    11041 catgcgtttg acagtgagta ttggttcaaa agctgttagc attttctata tcgtcatcaa
    11101 tgttctcttc ctagcccttg tcttctataa gatgtggcga caacagaaag ccttggcaga
    11161 agaagaggaa acagaagagc ttgcctaagt attgacaaaa aagaactatc aagatacaat
    11221 cttggtagtt gttttttgat tatagataaa atcatggagg tacatatgaa gacaatttct
    11281 ttagtttata ttagtttgag tggcaacact gaaagttttg tgacgcgctt gaaagactat
    11341 ctcttgtccc agtacaaagg gattgaggtt caaaagattc atatcaagga tttggtcaag
    11401 gaaggcaaaa atttctatga aatggaccat ccctatgtcg cttttttgcc gacctatctc
    11461 gaaggtggga atggcgtgga taacggagat gttgagattt tgacgacacc ggtgggagat
    11521 tttattgcct atggtaacaa tgctagtaag tgttttggtg tggttgggtc aggaaatcgt
    11581 aactttaata accaatactg cctaacagcc aagcaataca gtcaacgctt tggcttccct
    11641 gtattggctg actttgaaat gcgaggcatg ctggaagata tcaaacatgt cgcagctatt
    11701 atcgcagatt tgtatgagtt ggaaaaggag aattaatact caatgaaaat caaagagcaa
    11761 actaggaagc tagtcgcagg ttgctcaaag cacagctttg aggttgcaga tagagctgac
    11821 gtggtttgaa gagattctcg aatagtata
//
LOCUS       DAVAGB010000054        11714 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVAGB010000054 DAVAGB010000000
VERSION     DAVAGB010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11714
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.055"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(149..952)
                     /locus_tag="VQO19_001796"
     CDS             complement(149..952)
                     /locus_tag="VQO19_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HET1350018.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1555..2934)
                     /locus_tag="VQO19_001797"
     CDS             complement(1555..2934)
                     /locus_tag="VQO19_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET1350019.1"
                     /translation="MSEYWFSTNVDQIDEVDGKQCLIYSYYNVKASRNVEVLKGRSGT
                     KKGLDYWEPYAPQKQYEMERLPKNKYIGSSSTDRWDGIEKNVVFCDCKEYVSAFDLFF
                     YHYNFKKISTQRSKQDFIRLRSKPVADILKNNTSSYTRYKKEMVIDNVKVDDKVCEII
                     SEIMDESYTDIQILTHKLYSKGDDIKASKTIWMKKSGKEYSEAFAGTGEARIILLVND
                     IVNAQSNSLILIDEPEISLHPSAIYKFKEFLLQECLNKKHQIIITTHSTQLIKDFPRE
                     AVKLLVKNGEKVDVIENIDYQDAFFELGDVYHSRKMIYVEDRLAKYILEFVITHSGSE
                     NLKQNLVVRYIPGGANQIICNNILNSSYLDSDNHYFWLDGDQNTNVSESNNLMNYLEN
                     GVVISDKIPESDNKNLDDIIKLITGCPIKFNVSGNKGQKNNIELIAKQRSFIDYWAKY
                     VSYLPFPTP"
     gene            complement(2985..3149)
                     /locus_tag="VQO19_001798"
     CDS             complement(2985..3149)
                     /locus_tag="VQO19_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HET1350020.1"
                     /translation="MGKIVAIDLFSGAGGTTSGLKKSGIDVQVAVEIDSVAVKTYKLN
                     NPEVSVIDME"
     gene            complement(3230..5881)
                     /locus_tag="VQO19_001799"
     CDS             complement(3230..5881)
                     /locus_tag="VQO19_001799"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HET1350021.1"
                     /translation="MSKELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEGPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVVHDNVTKVATGEAGNVTDRWILHNLNETIGKA
                     TANFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQYAEGSIVTAAYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ECDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(5874..6452)
                     /locus_tag="VQO19_001800"
     CDS             complement(5874..6452)
                     /locus_tag="VQO19_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET1350022.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQSLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKYKPLKRHIEVSEREIIETAETLQLNSQHQPNELNH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(6452..7012)
                     /locus_tag="VQO19_001801"
     CDS             complement(6452..7012)
                     /locus_tag="VQO19_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET1350023.1"
                     /translation="MARTELPDKIETECLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYAFLKSEWEVI"
     gene            complement(6999..7448)
                     /locus_tag="VQO19_001802"
     CDS             complement(6999..7448)
                     /locus_tag="VQO19_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HET1350024.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVVPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(7860..8255)
                     /locus_tag="VQO19_001803"
     CDS             complement(7860..8255)
                     /locus_tag="VQO19_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET1350025.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLTLKGIGPATIKKLKENGIKFK"
     gene            complement(8351..8605)
                     /locus_tag="VQO19_001804"
     CDS             complement(8351..8605)
                     /locus_tag="VQO19_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HET1350026.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            complement(8615..9949)
                     /locus_tag="VQO19_001805"
     CDS             complement(8615..9949)
                     /locus_tag="VQO19_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HET1350027.1"
                     /translation="MTDERIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKDDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(9949..10182)
                     /locus_tag="VQO19_001806"
     CDS             complement(9949..10182)
                     /locus_tag="VQO19_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HET1350028.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            10213..10290
                     /locus_tag="VQO19_001807"
                     /pseudo
     CDS             10213..10290
                     /locus_tag="VQO19_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(10496..10636)
                     /locus_tag="VQO19_001808"
     CDS             complement(10496..10636)
                     /locus_tag="VQO19_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350029.1"
                     /translation="MKFFWGLLAIIFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(10633..10815)
                     /locus_tag="VQO19_001809"
     CDS             complement(10633..10815)
                     /locus_tag="VQO19_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350030.1"
                     /translation="MGLIKTLAKIYGNYFLTVQGVKVMKTIKKDDNAVVGLGKLFIAD
                     KLMDTARWLIKPEDKK"
     gene            complement(10817..11596)
                     /locus_tag="VQO19_001810"
     CDS             complement(10817..11596)
                     /locus_tag="VQO19_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350031.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
BASE COUNT         3434 a         2534 c         2112 g         3634 t
ORIGIN      
        1 cttgtgcaat acagaactaa atccttcgga taaattattt gtctaacttt ttggggtcag
       61 tacacctaaa actttgatga tatacgtttt cttgtgagaa tatttacttc atttttgcct
      121 aaaattcaat gtttactcag tatttggatt atgaaaaatc gaggtctaaa tctagataca
      181 ttttttctga agacaaatca ttttgaccac cgagcaagag attttcaaaa aaagctgtta
      241 aaaactcaga acgtcgctgt aaaatctttg cattatctaa taccaaggca tcacgaaaat
      301 atttggaatg ttgctgaaat ggtgtattat caatatcaaa accaaactca cgaagatact
      361 gaatcaaaaa gaccgttact gtccgagtgt ttccttcgcg aaatggatga atctgccaga
      421 ttcctgaaat aaaatgctgg atttgtttaa ccacatccgc ctgagttagt gtcgcatatg
      481 caacttgttt ttcctgatta aaatcataat ctaaggtcat ttgaatcatg gagtaatcag
      541 agtacacaac actttcacca ttcaaaacag gttcattctt tgtgatattg gtctgacgaa
      601 attgccccac cggaatagag ggttcaaata tatcttgaaa caactcctta tgaatagcaa
      661 gtaaggtcgc aggactaaag ctaaagcctc ttcgagacaa tagttctaca atacgtagag
      721 aaaccaagtc tgcctcttcc gtacttgcat caatagtatg gtgataagcc gttgcatcct
      781 cataaacctg ctcataagtc agttctcccc gggactgttt ctcagccaaa gattccatat
      841 acgctgatgg cactagattg tcaactttct gcagaccaaa acctatccgc cataaatcac
      901 gcttcgcttc ataagacaag tttggattgt caatgttgta agttgattgc atagaaatat
      961 cctttcaatt gtttttctgt gtcatcggta aattgtgaaa taggtatgga attggcgaaa
     1021 attataaaaa tccttcacaa taggttctat gaaatatata tacttcatct taatagtgag
     1081 caagctaaac ttagcatttc atgccctcat atgggatgtt ctttaactaa ataatatgat
     1141 tatcgagata tatctggata aatgaactaa taagtctgac gcgtagactt atcaaagtca
     1201 ttggcataca ccactatgaa ctcgttgatc tgttcaaatc ccaacacatt acctgagaag
     1261 aaagttgcaa tgttgttttt ggtgcgggtt tgaatttaaa aatttgttat gtagtaccta
     1321 atctaaggaa ttagaacaat gcctctaatt tttctttaat acactgaaac attgatgatt
     1381 ctggctgtat ttttgaaaca gctcttcttt gctcctggaa aatatcttca gaagttatat
     1441 tctctattcc taacgctact tgaatttttt tctaaaatat tcttttccgt tgccatcttt
     1501 agaaaaatca taaccttccc tatctacgct gttacataaa ttagctaaaa aaaactatgg
     1561 ggttgggaaa ggaagataag aaacgtattt agcccaataa tctataaagc ttctttgttt
     1621 cgcaattaat tcaatattat ttttttgccc tttattacct gaaacattaa atttaattgg
     1681 acatcccgtt atcaatttta taatatcatc aagattttta ttatctgatt caggaatttt
     1741 atctgatata acaacaccat tttcaagata gttcattaaa ttatttgatt cactaacatt
     1801 agtgttttga tctccatcaa gccaaaaata atggttatcg gaatctaaat acgatgagtt
     1861 taaaatatta ttacaaatta tttgatttgc tccaccaggg atatatctca ctactaaatt
     1921 ctgtttaaga ttctcactac ctgaatgagt gataacaaac tctagaatat atttagctag
     1981 tctatcttca acataaatca tcttcctaga atgatacaca tcacctaatt caaaaaatgc
     2041 atcctgataa tcaatatttt caataacatc taccttttct ccgtttttca ctaaaagttt
     2101 cacggcttct ctaggaaaat cttttataag ttgtgtagaa tgtgtagtga taataatttg
     2161 atgtttttta tttaaacact cttgaagtaa aaactcttta aatttataga ttgcactcgg
     2221 atgaagtgag atttcaggtt catctattaa tattaatgaa tttgattgcg catttactat
     2281 atcatttact aacaaaataa ttctagcctc acctgttcct gcaaaagcct cagaatattc
     2341 ttttccagat tttttcatcc aaatagtttt ggaagctttt atatcatcac cttttgaata
     2401 caacttatgt gttaaaattt gaatgtctgt ataagattca tccattattt cactaataat
     2461 ttcacaaact ttatcatcaa ctttaacatt atctataacc atttcctttt tataacgcgt
     2521 atagctactt gtattattct ttaaaatatc agcaactggt ttagatcgta atcttataaa
     2581 atcttgttta ctacgttgag tagaaatttt tttaaaatta tagtgataga aaaataaatc
     2641 aaaagcagaa acatattctt tacaatcaca aaagacaaca tttttttcaa tgccatccca
     2701 tctgtctgtc gaagaacttc caatatattt atttttgggt aatctttcca tctcatattg
     2761 tttttgagga gcatatggtt cccaataatc taatcctttt tttgttccag aacggccttt
     2821 aagaacttct acatttctag aagctttaac gttataatat gaatagatta aacattgttt
     2881 cccatccact tcatctattt gatcaacatt tgtactaaac caatattcag acacactttt
     2941 attggctgga gaaccatata aagcttgtaa aattgaagtt ttatttactc catatctatt
     3001 acagacacct caggattatt taacttataa gttttaacag ctacggaatc aatttcaaca
     3061 gcaacttgaa catctatgcc tgatttttta aggccacttg tagtgccacc tgcaccgcta
     3121 aataaatcaa tagcaacaat tttccccata gtattctcct aaagtttctc ctttttatta
     3181 taacattatc aaatgtaaaa cccaacccga gagggttagg tttttaacat catttcacca
     3241 acttcttcat ctcatcaata cgtgcgacgg tcgcgtcata tttagcttgg tagtcagctt
     3301 gtttgtcgca ttctttttgg acgacttctg gtttggcgtt ggctacgaag cgttcgttag
     3361 agagtttctt accaaccatg tccagttctt tttgccattt agcaagttcc ttgtcgagac
     3421 gggccagttc ttcttcaaca ttgaggagat cggccagtgg caggtagatt tctgctcctg
     3481 tgatgacact tgacatagcc agttcaggtg cagggatggt tgatgcgatt tccaaatgtt
     3541 ctggatttgt aaagcgtttg atgtagttga cattgctgtt aaagaaggct tccaagtcgc
     3601 tatcgcttgt cttaacaagg atggtgatag gtttgcttgg tgctacattt acttccgcac
     3661 gcgcattacg aacggcacgg atcaagtctt tgagactttc cacaccagtg tgggcagcaa
     3721 ggtcctcaaa ggctgggttg acagttgggt atgctgctgt cacgatagag ccttcagcgt
     3781 actgaccaaa gatttcttct gtcacgaatg gcatgattgg gtgaagaaga cggaggattt
     3841 tatccagcgt atagaggaga acagatcgag taatgacctt atcgtcttca ttgtcgctgt
     3901 aaagaacttc cttggtcaac tcaacatacc agttggcaaa ttcttcccaa atgaagttgt
     3961 agaggatgtg gccagcaaca ccaaactcaa acttatcaaa gttagcagtt gcttttccaa
     4021 tcgtttcatt gaggttgtgg agaatccagc ggtccgtcac attaccagcc tcacctgttg
     4081 caacttttgt gacattgtca tgcaccacat ccagcgtcaa accttcattg ttcataagga
     4141 tgtagcgaga gatgttccag atcttgttaa tgaagttcca tgaagcatcc attttctcat
     4201 aagagaaacg cacgtcttgt cctggcgcag aaccgtttga aaggaaccat cgaagggcat
     4261 cggcaccgta tttctcgata acatccattg ggtcaatccc gttaccgaga gacttagaca
     4321 tcttgcgtcc ttgctcgtca cgaataagac cgtggataag gacgttttgg aatggttgac
     4381 ggcctgtgaa ttccaatgac tggaagatca tacgagacac ccagaagaag atgatgtcgt
     4441 aacctgttac caaggttgaa gttgggaaat aacgtttaaa gtcttctgag tcgacttcag
     4501 gccagcccat ggttgaaaat ggccagaggg cagaactgaa ccaagtatcc aagacgtctt
     4561 cgtcctgagt ccatccgtca ccttctggag cttcttcgcc gacatacatt tcaccatcag
     4621 cattgtacca ggcagggatt tggtgacccc accaaagctg acgagagata acccagtcgt
     4681 ggacattttc catccattga aggaaggtat cgttgaaacg aggtgggtag aattcgacct
     4741 tgtcctctgt gtcttggttg gcaatggcgt tcttagccaa ttggtccatc ttgacgaacc
     4801 attgagtaga caagcgtggc tcaactacga cacctgtccg ttctgagtga ccgactgaat
     4861 ggacacgttt ttcgattttg acaagggcac cgatttcttc caacttagca acgactgcct
     4921 tacgagcttc aaaacgatcc atgcctgaaa attcaaaggc aagctcattc atagttccgt
     4981 cgtcgttcat gacgttgact tgtggcaagt tatgacgttg gccaaccaag aagtcatttg
     5041 gatcgtgggc aggtgtgatt ttcacgacac cagtaccaaa ctcaggatct gcgtgctcat
     5101 ctccaacgat tgggatgagt ttattagcga ttggaaggat gacgttttta ccaatcaagt
     5161 ccttgtagcg cgggccttct ggattaaccg caaccgcaac gtccccaaac atagtctcag
     5221 gacgagttgt agcaacttca agggcgcgtg aaccatcttc cagcatgtaa ttcatgtggt
     5281 agaaggcacc ttccacatcc ttgtgaatca cctcaatatc agaaagggct gtgcgagctg
     5341 ctgggtccca gttgatgata aactcaccac ggtagatcca gcctttcttg taaaggtcca
     5401 caaagacctt acgaacagct tttgacaaac cttcgtcaag agtgaaacgc tcacgagaat
     5461 agtctacaga gagccccatc ttgccccatt gttccttgat ggtagtggca tattcgtctt
     5521 tccattccca gactttcgtc aagaaagact cacgaccaag gtcatagcgg gaaatgccct
     5581 caccacgcaa gcgctcctca accttagcct gagtcgcaat accagcgtgg tccattcctg
     5641 gaagccaaag ggtatcaaaa ccttgcatgc gtttttgacg gatgataata tcttgcaaag
     5701 ttgtatccca agcgtgacca aggtgaagtt tacctgtaac gtttggtggt ggaataacga
     5761 ttgaataagg cttagccttt tgatcgcctg aaggcttgaa aacatcagca tcaagccatt
     5821 tttgataacg accagcctca acctcggctg gattgtattt aggtgaaagt tctttagaca
     5881 tgtgtgtgtc ctttctctat tttgtttatt ttattttgaa tttgcttagc agcttcttct
     5941 gcagacaaat tcgtattatt tattttaaag tagtggttca actcattcgg ttgatgttgg
     6001 gaatttaatt gaagtgtttc agcggtctct ataatttctc tttcagatac ctcaatatgt
     6061 cgttttaagg gtttgtactt taatcgattc tccgttcgat ttcgacgtat gcactcttca
     6121 agacttgttt ccaactcaac aaaaagaatc tcttgatgat aatcatccaa caaactctga
     6181 atttgcttta aatatatcag atgatactga tttgaaaaat caattacatc tgttaaaatt
     6241 actgatcgct gatttcttgc actcgctcca aggaatgaaa aagtgattcc acgaacaaat
     6301 tcccacattt cctctgtata gtcctgatag atttctagtg caaaatcaat ggcttgatgg
     6361 ttataaaaga gggtagcatc cgtcagtcga gataattctt gaccaatggt catttttcct
     6421 gatgctggag caccaatgat gaaaagatgc atcaaatcac ctcccactca ctcttcagaa
     6481 aggcatatct caaatcatca cagcagttgc cttgagcatc tttgcggtct cttatgcgag
     6541 cttcgagggt aaagccaagt ttttccgcga ctcgttgact ttgaaggtta tatccaaagc
     6601 aagttagttc aatcttgtga agacccaaat ctttaaaggc taagtcaatc aaggcacgcg
     6661 cagcttctgg cacataacct cgcccccaat agtctgggtg taaggtatag ccgatttcca
     6721 gcacatcatc ttcatggcga tggttgaaat cgacagagcc aacgatctta tccgttcctt
     6781 tgacgacaat cccgtagcct gctgggagat tttccttttg attacgctcc ggaagaatgt
     6841 gctccagata ataaatctca tcttccaagg tcttgactgg aggaaaacct gctggatagg
     6901 cgacctctgg caaactagca tagtcaaaga tatcctcagc atccgccaca gtacggactc
     6961 gtaaaacgag acattctgtt tcgattttat ctggtagctc agttcttgcc atccttcttc
     7021 ctcgcttttt tgatgaaact gcccttcata tctacacgct tgtccagata gcgataaacg
     7081 cgctgatatc catctcccat gaaataggtt ggggcaaaca gttgattttt aaaatgtccc
     7141 ttttcatcca ggagttctgg aacaacaagt cgctcaagaa tcttggcaaa gatgtggcaa
     7201 ataccgtctt cctcaacaat cctatctacc cgacaatcta aaacaagtgg acaggcgtct
     7261 aaaataggag tctgagttcg ttcagaaatt tcataatgca ctcccaaacg ttccaatttc
     7321 tcctgatgac tgataaaacc agcctgctcc atcgcaagca tagaagtttc atcagaaata
     7381 ttcacagtaa atttttgata ctgtttgatc tgctctgcgg cattctctct cgcaacgact
     7441 ccaatcacaa cccaatctcc tagactataa gaggaactac aggtcgtgat gttatagcca
     7501 aaattctaat cttgatatcc taaaataaaa acaggaaaac cataatatag tttacttgtg
     7561 ttaaaagatt gcttcataac aacccccttt gactaagacg taaaagaaaa gccctgccat
     7621 ctacatgaca gggacgaatg tgtttatccg cggtaccacc caatttcggg ccaagcccgc
     7681 atctttagtc tttaaaataa aaagacagaa atatttcatt ttttcagtca ttagcaacca
     7741 gttttgacac atttgtggac ttctcagcgc cgccactttc tgtaaaatgt gggattcaaa
     7801 acacctctaa tggctctatt gtagcaagtt tttctcggaa atgcaaggct caaaaaaaat
     7861 tacttgaact tgatgccatt ttctttcaat ttcttaatgg tagctgggcc gattcctttc
     7921 aaggtaagga gttctttttc agtccagttt ttgaaatctg aagcagactt gattccttca
     7981 tcatagaaag tcttggcacg atcaagtgga agtccaccca agtttgctgc aaaatcttct
     8041 acagaattag ctactttttg agcttgctct ttggtagctt ctactgcttg ttcaactttt
     8101 ttagaaacag ccttaccagc tgcgcttgct gactgttctg cacgcttcac gacttttttt
     8161 gtctcatcta caaccttagt cacagtactt gaaaaggcac ctgcgcgacg gaggccattt
     8221 cgtaattgtt ttttacgatt gagtttcttt gacatgataa aatcctttca ataaaaaatc
     8281 cctgctctga caaggattta acataaacat tctatcaaga ttttagtgaa aaatcaagaa
     8341 tctttctcgt ttaataattt cgctcaccaa acaagccttc tggcaaatca tggaatccct
     8401 tgcctgcttt gaagttttca aacttaccaa gcaagaactg ataagcatcc aagcgactct
     8461 cgtagcgaat catggcatct ttggcacgct cgtcctggtc ttcttcgtaa actttttgac
     8521 tttccttgtg cgccatgtcg ttaatcatga tttgggtatt gacccaagct tcaaattcct
     8581 tcataaattc ttgttcgtaa ctcatttttt ctccttattc taatccacga aaatagtccg
     8641 tatcaatctc acggtagggc tggatatcct gaacatactc caacactcct tggaattctc
     8701 cgtcttcatc gtgtactgca gcataggtga tgtggacaaa cttacctcgc gactcagact
     8761 tgaaccacat ttcatacttg tctttgcttc cctcacgaag ccccttcatg atagttttga
     8821 ccttgtccaa gtacttaggc ggatggcaga gttcgacatt gcgcccgact tgagacggcg
     8881 tccgtttgaa aatcatctca tcagctggcg tattgtcatt gtaatactgg aaaatatcat
     8941 ctttattgac aaaggtaatc tccataggga ggtgattgag gatgagattg gcctgctcga
     9001 ctgaaagata gccattacca aaagcctgtt gactatggcg gtccagcaca gcttcctttt
     9061 ccttaggggt aaaggtaatg gtaaaatggc cttctggcgt atctatgact tgttgaactt
     9121 gaccttctgc cgtatctagc tgtacaggct cctctgcaat cttttcctca ataaagctct
     9181 gtcgttctgg cacccatttc tctgacggac ggatgatggc atagccatag gcatcgctct
     9241 cctccgcaat ctgaagccag tcatcctgag taaaagactc aaggagaatc atgaggagga
     9301 tggactcttc cttgaaaatc atactttcaa actctgtcgc aaaagcttca aaagcttcct
     9361 ttacactgct aattgacact tctggtagtg acttggctgt cgttagagct gtttgaaaga
     9421 gttccctaat ctgatcatcc actccccaca taactttggg aggtgaatcg tgtccatagc
     9481 gctccatgat aggaaagaag agttcttctt tacgttggta atggatgtca aattgcccca
     9541 caagtcccat ctgacgcacc aagcccttgc gcatctccgc aagcatttcc tcgtcttcca
     9601 tcaactcata ggtatctaac aatctacgaa tgcgaatcaa agctgcacgg agggccaaat
     9661 tttcttcctt aaagacacga actgggtgcc cagggtgttc ggtatctaaa acttcgacac
     9721 ctttgatagc atttttaaaa agattggcat ggacatcaca gagttccata acatcttcaa
     9781 aagtgacgcc cgaatccgag ttcatcagct cgtgctccat aagggaaatc tcgatggctg
     9841 acacgcccgt aaaggtcgca tcaaagcgat cttgaaccga ctcaggagag gcgccattgt
     9901 gcaattctaa caaaatatcc cgtaggatat gaatccgttc atctgtcatt agtctaatcc
     9961 aatcacttcg tagccattcg cttccagtgt gcgtacaatc ttgtccatag gagttcctgc
    10021 tagcttagaa ccctgtttaa gtgatacttt acgaccaact gtattgcgca ttaagggatt
    10081 ggcaaggggt ttaaaaccca actccactag aatttccaag acttctggat gcttgtccac
    10141 cacttctgca acaggaattg acacatcgat gatattgtcc atgacgacct ccattgtatg
    10201 ttctaatact caatgaaaat caaagagcaa actaggaagc tagccgcagg ttgctcaaaa
    10261 cagtgttttg aggttgtaga tagaactgac gaagtcagct caaaacaccg ttttgaggtt
    10321 gtggatagaa ctgacgaagt cagtaaccat acctacagca aggtgaagct gacgtggttt
    10381 gaagagattt tcgaagagta taaaatgatt ttactgctta tattatacca tatggaaaga
    10441 gaataaaaaa ctagcagtgg agttcctgct agttctctgc gacttggatt accatctaga
    10501 taagtttaaa gaaccaatcc aatatcttgt aaaacagcaa ttggactgca aaagagatga
    10561 tcatccaaaa gaatttcaca atcccaataa tcggtttgat aaaaataatg gcaagaagtc
    10621 cccagaaaaa tttcattttt tatcctctgg cttaatgagc caccgagccg tatccattaa
    10681 cttgtcggca ataaaaagtt tccccagacc gacaacggca ttatcatctt tctttatcgt
    10741 tttcattact tttacacctt gcacggtcaa aaagtaatta ccataaattt tagctagagt
    10801 ttttatgagt cccatattac tctccttcga tgatttcagc ctcttttcgg attgtttcaa
    10861 catcttcttg atattgaact tcactatagt taactagctt ggacaattct ttctgcaagc
    10921 tttcacccat cggtttcata gttgcaaagg ttaaaccacc tgaaatgata ccacccaaga
    10981 taggaataaa tttccccatt cctttggcca gccctccctt ggtaagattc acaccaaata
    11041 ttcttaagac ttttttcaaa ataggatacc aaagcgtctt tgttaaagct ttattaggta
    11101 ctgttttcat tacctgtttg gcaattgtta taccaccagc acgtagcaaa gcagcagttc
    11161 cattcacccc caacatgacg cctagataaa gcaaaagggt attttgagca tcttcactca
    11221 actcatcgcg tgaagcccaa agatcctcat aaccataaat ataacctaat tcttgggcca
    11281 atttcagaga gaaaccataa aattgagcca catcagctgg aatggtaatt gccatagcaa
    11341 gccctccagg taatcctgcc aaaacagaag tcccactcgc taataaaaca ttatccctaa
    11401 tacaggcatt agccactcga tctaagattt cttgagataa gagagacgtt ggaccttgtt
    11461 ccaataaggt aggaatgtcc tgtggaccca attctttgga aaacttatcc actaaaaatt
    11521 tcgaacgatc aaccttaaca acaggtagtt tcaccacttg ttgcaatact tgcatagcta
    11581 agtcttgttc agccatatac aaactcctta tttctttttt gcaccttatc atattatatt
    11641 tcctacaaaa aaagcatttt ctaattagat aacattaaaa aatacagaat ccctttttta
    11701 tattaaaacg aaac
//
LOCUS       DAVAGB010000055        11617 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVAGB010000055 DAVAGB010000000
VERSION     DAVAGB010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11617
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.056"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            432..1142
                     /gene="deoD"
                     /locus_tag="VQO19_001811"
     CDS             432..1142
                     /gene="deoD"
                     /locus_tag="VQO19_001811"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET1350032.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(1165..1689)
                     /locus_tag="VQO19_001812"
     CDS             complement(1165..1689)
                     /locus_tag="VQO19_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HET1350033.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(1742..1978)
                     /locus_tag="VQO19_001813"
     CDS             complement(1742..1978)
                     /locus_tag="VQO19_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HET1350034.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(2046..2966)
                     /locus_tag="VQO19_001814"
     CDS             complement(2046..2966)
                     /locus_tag="VQO19_001814"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HET1350035.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            3164..3568
                     /locus_tag="VQO19_001815"
     CDS             3164..3568
                     /locus_tag="VQO19_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350036.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGICFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKAKQ"
     gene            3784..4365
                     /locus_tag="VQO19_001816"
     CDS             3784..4365
                     /locus_tag="VQO19_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET1350037.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETSGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            4362..5639
                     /locus_tag="VQO19_001817"
     CDS             4362..5639
                     /locus_tag="VQO19_001817"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HET1350038.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILVPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMNFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            5657..6319
                     /gene="deoC"
                     /locus_tag="VQO19_001818"
     CDS             5657..6319
                     /gene="deoC"
                     /locus_tag="VQO19_001818"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HET1350039.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSTVKAFETKEAIQNGADEIDMVINVGALKSGDL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVLACQLAQKAGADFVKTSTGFSTGG
                     ATIADVRLMRETVGPDMGVKAAGGARSYADALTFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            6306..6695
                     /locus_tag="VQO19_001819"
     CDS             6306..6695
                     /locus_tag="VQO19_001819"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET1350040.1"
                     /translation="MATTELIELAIEISKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            6786..7838
                     /locus_tag="VQO19_001820"
     CDS             6786..7838
                     /locus_tag="VQO19_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HET1350041.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQDWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLTVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            7982..9517
                     /locus_tag="VQO19_001821"
     CDS             7982..9517
                     /locus_tag="VQO19_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1350042.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            9510..10568
                     /locus_tag="VQO19_001822"
     CDS             9510..10568
                     /locus_tag="VQO19_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET1350043.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            10571..11527
                     /locus_tag="VQO19_001823"
     CDS             10571..11527
                     /locus_tag="VQO19_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET1350044.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         3314 a         2070 c         2648 g         3585 t
ORIGIN      
        1 ggtttgaaga gattttcgaa gagtataaac agaaaggtag agcgcgtgtt ctaatttgaa
       61 cacgagtaga aaacttttct aaaaacaaaa acgaaaggat gggtaaactg tattcgctga
      121 actgaatacg ggcgactctc ctctaaatca aaattaagaa aggaattgac cccaccctaa
      181 aagtagtggg aaaaagatag ttgatctagc gagcatcgct cactgcgccc aactcctatt
      241 ttcccttcgc tttttgatgg gtttggtatc tttctcaata taaaatataa aataaagaaa
      301 ggtagagcgt gtgttttgat ttgaacacga tcggaaaact cggaaaatag ataatctgac
      361 tgaaaaatca ggatttctcg tcaggttcct aattttcagt cgttttcttc tcgctctttg
      421 tatcataaat tatgtctatc catattgctg ctcagcaggg tgaaattgct gataaaattc
      481 ttcttcctgg ggatcctctt cgtgctaagt ttattgcgga gaatttcctt gatgatgctg
      541 tttgttttaa cgaagtgcgt aacatgtttg gttacactgg tacttacaag ggtcactgtg
      601 tatctgtcat gggaactggg atgggaatgc catctatttc gatttatgcg cgtgagttaa
      661 tcgtagacta cggtgtgaag aaattgattc gtgtgggaac tgcaggttct ttgaatgaag
      721 aggttcatgt tcgtgaatta gttttggcgc aggcggctgc aaccaactca aacatcgttc
      781 gtaatgactg gccacagtac gattttccac aaattgctag ctttgatttg cttgataaag
      841 cctaccatat cgccaaagaa cttggtatga ctactcacgt tgggaacgtt ttgtcatctg
      901 atgtctttta ctcaaattac tttgaaaaga atatcgagct tggtaaatgg ggagtcaagg
      961 ctgtggaaat ggaagcagca gctctttact atcttgctgc ccaataccat gttgatgcgc
     1021 tagctatcat gaccatctct gatagcttgg tcaatccaga cgaagacaca actgcagaag
     1081 aacgtcaaaa taccttcact gatatgatga aggttggttt ggaaaccttg attgcagaat
     1141 aattatagcc aaaaaggaag ccctttatga attgtaggac ttccttttct tatccagaaa
     1201 ttgatctagc tctctctgat ttcgaagaat agtgacttta tgtgaatatt cttggcaaag
     1261 tttttggtaa ttttcttttt gagttttgct acgcccatcc caaagaatcc atctgataaa
     1321 ctcccactca aagcgttcag ggcaatctgc cgccatactt tctctgactt ttccacggta
     1381 tttaagataa cgcttaaagg ctctaaagag acaggtcaat ggcaaaaaat tgagaaagat
     1441 gatttggtca gcttcttgca ttcgttcttg gtagtagcac caagaataat taccatcgat
     1501 gacccaagct ttatgcttgg tgagaaagtt ttttatctcg gttaacatcc attcgcagtc
     1561 actgtcttgc caaccaggtt gaaattggag tgtgtccatg tgcagttttg gaatggagta
     1621 gtagttagat aacttttctg ctagagttga cttaccagaa ccagaatatc cgataattgt
     1681 gattttcatt ttctaccttt tcctatttgg agacaaaaaa acagcctcta tggactgttt
     1741 cttatttagc aagtttagct gaaagacgag ctttatcgcg gcttgctttg tttttgtgaa
     1801 tcaaaccttt agtttctgct ttatcgatag ctgagctagc agcacggaaa agttcttcag
     1861 atgggtttgc ttcgaaagct tttatagcag tacgcatagc tgatttttga gctgagttct
     1921 tttcgttttg tttaacgttc aattcagcgc gtttgatagc tgatttaatg tttgccaatg
     1981 ttcttacctc catatttact aactatacca ttatatatga aaacttacgt tttgacaagg
     2041 gaaaattatt tttttaagta aatttcatcg atttcatggt tcttgctttt atgaagaatc
     2101 acttctgcac gatttctggt tggttcaata taattttgta gatttgtgag attgatactg
     2161 gtccagacct gatgggcaaa ggcttccact tccccaatcg gcatctgagt aaaacgataa
     2221 tagtagctat cagggtcgtt ttgggctaga ctcagcattt tcaagaaacg gtccagatac
     2281 caactttcaa tatcatccac tccagcatct acatagatgg aaaagtcaaa gaagtcagtg
     2341 atatagagac gatcgttttg tggattttga aagacattga ttccctcaac aattacaaaa
     2401 tcagcagctt tgacactttg tttctcttcg ggtacgatgt cgtaaacttc atgagaatag
     2461 acaggaatat ctacatcttg tccatttttg atgcggtcca agaagttgag aagagcttcc
     2521 atatcatagc tttcaggaaa tcctttacga tttaaaatcc cctgctcaat caaggtttga
     2581 ttgggataga gaaaaccatc agttgtaacc aactcaaccg tagcatctgt aaacgtacgg
     2641 gacagtagga tttgaagtag gcgactggtt gtggattttc caacggcaac actcccagaa
     2701 accccaataa taaaaggttg agatttactt tcacgttgga ggaaaattcc ttttgaaaag
     2761 gctaaatctt ccttagttcg cttgtaaatc tgaatcagat gagctaaggg gagatagata
     2821 tctgtaacgt cttggagact gatttggtca ttaaaactct tgatagattc caattcttct
     2881 tctgtcaaag gaggtgttgt ctttcgatgt aaagattgcc aagtctggcg gctgattttt
     2941 tcaaaatgta aaaattcgtt ggtcatttgt tttcccctag atattttgtc tatcatacca
     3001 taaaaatcta aaaaaataaa gcggtttctt gaatgtggta agtcaatggt atatagtata
     3061 agtgatcaat ttattgatga aataggagat agattctact gatttataag tttataagct
     3121 tataaagggg gctttttagt tcacaactta taggaggtgt actatgaaaa tcttaaaacg
     3181 ttacatattg gaactctgtt ttattttaag ttttgcttta ccttttataa aaggagccaa
     3241 tgcagataat ggtatatgct ttgtggaaac ctattacggt tttacttttt tgatggaaca
     3301 tgctattgta acagctgtct ttatctattc gtttttaatt gctttcttac taaaaaaacg
     3361 atgggcgaaa tggattgctg ctggtagtta ttgcttttta gtcctatgga ttgcgacaga
     3421 gggttatttc ttccgcatgt cactagaaga tttgatacga ctttggacaa gtttggaaat
     3481 cctgacacaa acgtatcagt tgggctttta tctaaacatt ttgttgggaa ttttgttgat
     3541 aataaagtat tttaaggcta agcaatagaa ataataatct gcctgattat agatgataaa
     3601 ctttttgttt ttatctggac tgtgatattt atagttctaa atggtttatt atttataagt
     3661 gttgaaagag attgaagaaa atggcttcgt gactcgcttt cttcggtctt tttcgtttta
     3721 ttatcaattt gtaaacgatt tacaatttga gtcaaattat ggtaaaatag tgtcatgagt
     3781 aaaatgtatt atgcagaaaa tcctgacgct gctcacgaca ttcatgagtt gagagtagag
     3841 ttgttgggac aaaaaatgac ctttttaacg gatgcgggtg tttttagcaa gaaaatagtt
     3901 gactttggaa gtcaactatt gctcaagtgt cttgaggtca accaaggaga aactgtcctt
     3961 gatgtaggct gtggttacgg acctttgggt ttgtccttag ctaaggctta tggagttcag
     4021 gctactatgg ttgatatcaa cactcgtgcc ttagatttag ctcggagaaa tgctgaaaaa
     4081 aataatgcaa aagcgacgat tttccagtcc aacatctatg aacaagttga aggacatttt
     4141 gatcatgtca tttccaatcc tcctatccgt gcgggcaagc aagtcgttca tgaaatcatt
     4201 gagaaaagta aagatttctt ggaaactagt ggggatttga caatcgtcat ccagaaaaaa
     4261 caaggggctc caagtgctaa gtccaagatg gaggatgtgt ttggtaattg tgaaatcctt
     4321 aaaaaagaca aaggatacta tatccttaga agtgtgaaag aatgagagca gttgatttaa
     4381 tacaaaaaaa acgagacggt caagaactga cttcaagtga aattgaatgg ctggtagaag
     4441 gctatgtgtc aggaactgtt cctgattatc agatgtctgc ctttgctatg gctgtttatt
     4501 ttaaaggaat gacgactcga gaaatctctg atttaacgat gaatatggtt aagactgggc
     4561 aagagtttga cctgtcagcc attgatggtg tgaaagttga caagcattct actggtggtg
     4621 tcggcgataa ggtaaccttg attttagttc ctcttgttgc tagcttcggt gtgcctgtag
     4681 caaaaatgag tggtcgtggt cttggtcata caggcggaac aattgataaa ttggagtcca
     4741 ttaagggcta tcaagtagaa cgtagtcaag aggattttat tcgtcaggtt caggatattg
     4801 gagtatctgt cattgggcaa tcagaccagc tggtcaaagc agataagctt ctctatgccc
     4861 ttcgtgatgt gaccgcaact gtcgacacga ttcctttgat tgcgagttcg gtgatgagca
     4921 agaaaattgc ggcaggggcg gatgctattt tgctagacgt gactgtcggt gagggtgcct
     4981 tcatgaagac ggttgatgag gcacgtgagt tggctcaaac tatggtagat cttggtaagg
     5041 ttgttggacg gaagacagta gcagtgatta cggatatgag ccagcctttg ggacgagcga
     5101 ttggaaatcg tctggaaatc cttgaagcat tggagatttt gcaaggtcaa ggacgtcagg
     5161 atattaccca ctttatttgt gaattggctc aaattatgct tggtttggca aatgttaaca
     5221 aaactgttga agaagttcgc caacatcttg agaatggtca agcactggct aagtttgagg
     5281 aaatggtgca agcccaaggt ggagacttgg aagacctcta tcgtcctgta aatgtagctc
     5341 atgtggtgga aatccctgct caggaaacgg gtgtcatttc agctcttcca gctatgaact
     5401 ttggtcttta tgccatgagg ctgggtgctg gtcgtgcagt taagtctgat gccttggact
     5461 atgaaacagg aattgttttt gaaaagaaga ttggagactc cgttcaaaag ggtgaaattg
     5521 ttgcaaaagt atacacaaat gaaaaaattc cacctcaact agttacagat ttccaaaaat
     5581 gtgttaaaat aagtgatgaa gtgaaaaaaa tccgtgaaat tgtagaaatc atctcctaaa
     5641 tggagggaaa accgaaatga aattaaataa atatatagat catacgcttt taaaacaaga
     5701 tgcaaagaaa aaacaaattg atagtttgtt gtctgaggct agagagtatg gctttgccag
     5761 tgtttgcgtt aatccgacct gggttgaaca tgctaaaaaa ggacttgaag gcacagatgt
     5821 taaggtttgc acagtagtag gtttcccctt gggagcaaca acttcaactg tgaaagcttt
     5881 tgaaacaaaa gaagctatcc aaaatggggc tgatgagatt gacatggtaa tcaatgttgg
     5941 ggctctcaag tcaggtgatt tggccttggt tgagtcggat attcgtgcag tagtggaagc
     6001 aagtggggac aagttagtga aagttattat tgaagcttgc cttctgacag accaagaaaa
     6061 agttttggct tgccaattag cccaaaaagc aggagctgac tttgtcaaaa catctactgg
     6121 cttttcaact ggtggtgcta cgatagcaga tgttagatta atgcgtgaaa cagttggacc
     6181 tgatatgggt gtcaaggccg ccggtggagc tcgttcttat gcagatgctc ttacctttgt
     6241 cgaagcaggt gcgacccgta tcggaacgtc agctggggta gctattttaa aaggagaatt
     6301 ggcagatggc gactactgag ttgattgaac tggcaattga aatcagcaaa catgcctatg
     6361 tcccctattc tcactttcct atcggagcag ttttagtagc caaagacgga agtgtttaca
     6421 cgggagtgaa tatcgaaaat gctagctatc ctttgaccaa ttgcggtgag agaacagcta
     6481 tttttaaggc tatatctgaa ggccaaagag aattttcaga attgattgtc tatggtcaaa
     6541 ctgaaaaacc gatttcacca tgtggtgctt gtcgccaagt aatggtcgaa ttttttgaac
     6601 aagatttaaa agtgacccta gtcgcaaaag ataaatcgac ggtcgagatg acggtcgggg
     6661 agttacttcc atactctttt acagacttaa attagtctga gtcgctcttt gagtggcaag
     6721 ggtctttgtg accaatcaat ccatacttgc aacatcgttg cacatcttat ttaggaggtt
     6781 cagtaatgaa caagaaacaa tggctaggtc ttggcctagt tgcagtggca gcagttggac
     6841 ttgctgcatg tggtaaccgc tcttctcgta acgcagcttc atcttctgat gtgaagacaa
     6901 aagcagcaat cgtcactgat actggtggtg ttgatgacaa atcattcaac caatcagctt
     6961 gggaaggttt gcaagactgg ggtaaagaac acaatctttc aaaagataac ggtttcactt
     7021 acttccaatc aacaagtgaa gctgactacg ctaacaactt gcaacaagcg gctggaagtt
     7081 acaacctaat ctttggtgtt ggttttgccc ttcacaatgc agttgaagaa gcagctaaag
     7141 aacacactga cttgaactat gtcttgattg atgatgtgat taaagaccaa aaaaatgttg
     7201 cgagcgtaac tttcgctgat aatgagtcag gttaccttgc aggtgtggct gcagcaaaaa
     7261 caactaagac aaaacaagtt ggttttgtag gtggtatcga atctgaagtt atctctcgtt
     7321 ttgaggcagg attcaaggct ggtgttgcgt cagtagaccc atctatcaaa gtacaagttg
     7381 actacgctgg ttcatttggt gatgcggcta aaggtaaaac aattgcagcc gcacaatacg
     7441 cagccggtgc agatattgtt taccaagtag ctggtggtac aggtgcaggt gtctttgcag
     7501 aggcaaaatc tctcaacgaa agccgtcctg aaaatgaaaa agtttgggtt atcggtgttg
     7561 accgtgacca agaagcagaa ggtaaataca cttctaaaga tggcaaagaa tcaaactttg
     7621 ttcttgtatc tactttgaaa caagttggta caactgtaaa agatatttct aacaaggcag
     7681 aaaaaggaga attccctggc ggtcaagtga tcgtttactc attgaaggat aaaggggttg
     7741 acttgacagt aacaaacctt tcagaagaag gtaaaaaagc tgtcgaagat gcaaaagcta
     7801 aaatccttga tggaagcgta aaagttcctg aaaaataatg gatggaagtc atttcttagg
     7861 aagcggccaa gggccgcttt tttaagagtt gagacaaagt cattttgtct cagtaaagct
     7921 tgctactaga caaactagca agttttattg aaataaaata agactctgaa aggaagagca
     7981 catggcacac gaaaatgtca ttgagatgcg tgatattacc aaggtgtttg gtggatttgt
     8041 tgccaacgac aaaatcaact tgcacctacg aaaaggtgaa attcatgcac ttttaggaga
     8101 aaatggggct ggtaagtcca cgctaatgaa catgttagca ggccttcttg aaccaaccag
     8161 tggtgaaatc gcggtcaacg gtcaagttgt caatctcgac tccccatcta aagcagctag
     8221 cttgggaatc gggatggttc accagcactt tatgttggtt gaagccttca cagtggctga
     8281 aaacatcatt ttaggtagtg aattgactaa aaatggtgtg ctagatatcg ctggagctag
     8341 caaagaaatc aaggctcttt ctgaacgtta tggcttagct gttgaccctt ctgccaaggt
     8401 agcagatatc tcagttggag cccaacaacg tgtagaaatt ttaaaaacac tttatcgggg
     8461 ggctgatatc cttatctttg acgaaccaac ggctgttttg actccatcag aaattgatga
     8521 gttgatggct attatgaaaa atcttgtcaa agaaggaaaa tcaattatct tgattaccca
     8581 caaattggat gaaattcgcg cagtttctga ccgtgttaca gttatccgtc gtgggaaatc
     8641 aattgaaacc gttgaaattg caggggctac caatgctgat ttggcggaaa tgatggtagg
     8701 acgttctgtt tcctttaaaa cagagaagca agcctctaaa ccaaaagaag tggttttgtc
     8761 tatcaaagat ttggtggtca atgaaaaccg tggtgttcca gctgttaaaa atctgtcctt
     8821 ggatgttcgt gctggagaga ttgttggtat tgcggggatt gatggaaatg gtcagtctga
     8881 actgattcaa gccattacag gtcttcgtaa ggttgaatct ggtagcattg agctaaaagg
     8941 agattcaatt gtaggcttgc acccacgtca gattacagaa ctaagtgttg ggcacgttcc
     9001 agaagaccgt caccgtgatg gcttgatttt ggaaatgatg atatctgaaa atattgccct
     9061 tcaaacctac tataaagaac cacatagtaa aaatggaatt ttgaattatt caaatattac
     9121 ttcttatgct aaaaagctga tggaagagtt tgatgttcgc gctgccagtg aattagttcc
     9181 tgcagctgca ctctcaggag gaaatcaaca aaaagcaatt attgctcgtg aaattgatcg
     9241 agatcctgat ctccttatcg ttagccagcc aactcgtggg ttggatgtcg gtgccattga
     9301 gtatatccac aaacgcttga ttgaagagcg tgataatggc aaggctgtcc ttgttgtcag
     9361 ctttgaattg gatgagattt taaacgtctc agaccgtatt gccgttatcc acgatggtaa
     9421 gattcaaggt attgtatcac cagaaacaac caataaacaa gaacttggtg tcttgatggc
     9481 tggtggaaac ttgggaaagg agaagagtga tgtctaaaaa attacaacaa atttcggttc
     9541 ccttgatttc tgtattccta ggaattttac tcggagccat tgtcatgtgg atcttcggtt
     9601 atgatgctat ttggggctac gaagaattgt tctatacagc ctttggcagt ctgcgtggga
     9661 ttggagaaat cttccgtgct atgggtcctc tggtcttgat tggtcttggt tttgccgttg
     9721 ccagtcgagc tggtttcttt aacgtcggac ttcctggtca ggctttggca ggttggattc
     9781 tcagtggttg gtttgccctg tcgcatccag atatgccccg tcccttgatg attctagcaa
     9841 ccatcgtgat tgccttgatt gctggtggga ttgtcggagc gattccaggt attcttaggg
     9901 cctatctagg gacgtcagag gttattgtaa ccatcatgat gaactacatt gtcttgtatg
     9961 tagggaatgc ctttatccat gctttcccta aagacttcat gcaaagtaca gattcgacca
    10021 ttcgtgttgg ggctaatgca acctatcaga caccttggtt ggctgagttg actggtaact
    10081 cacggatgaa tattggtatt ttctttgcca tcattgccgt tgcagttatt tggttcatgc
    10141 tcaagaaaac aactcttggt tttgaaatcc gtgcagttgg tcttaatcca catgcttcag
    10201 aatatgctgg tatttctgcc aagcggacta ttatcctatc tatgattatt tcaggtgcct
    10261 tggcaggtct tggtggagct gttgaaggtt tgggaacctt ccagaacgtc tatgttcaag
    10321 gttcgtcatt agctatcgga tttaacggaa tggcggttag tttgcttgcg gccaactcac
    10381 caattggtat actctttgca gccttcctat ttggcgttct ccaagttggg gctcctggta
    10441 tgaatgcggc gcaggtacca tctgagcttg tcagcattgt aacagcgtct attatcttct
    10501 ttgtcagtgt tcattacctt atcgaacgct ttgtcaaacc gaaaaaacaa gttaaaggag
    10561 gtaagtaaag atgtctatta taaccttgct ccccctcttg gtgtcttcta tgctgattta
    10621 ctcagcacct ctcatcttta caagtatcgg tggtgttttc tctgaacgtg gtggtgtggt
    10681 aaacgttggc cttgaaggaa ttatggttat gggtgccttt tctggagttg tctttaacct
    10741 tgaatttgca gaacaatttg gagcagcaac tccatggcta tccttgcttg tagcaggatt
    10801 ggttggtagt gttttctcta tcatccacgc agcagcgacg gttcatttcc gtgcagacca
    10861 tgttgtcagc ggtacggtat tgaacttgat ggcgcctgcc ttggctgttt tcttagttaa
    10921 agttctttat aacaaaggac aaaccgacaa cctaagtcaa acttttggac gctttgattt
    10981 cccagtcttg gcaaatatcc cagtgattgg tgatatcttc ttcaagtcaa ctagtctact
    11041 tggttatctg gcgattgcct tctcattcct tgcttggttt attctcttta agactcaatt
    11101 tggtcttcgt ctccgctctg tcggtgaaca tcctcaagca gcggatacct tgggaatcaa
    11161 cgtctacaag atgagatatt tagggattat tatttcaggt tttctaggtg gaattggcgg
    11221 agcgatttat gcgcaatcaa tctcagttaa cttctcagtg acaactattg ttggacctgg
    11281 atttatcgcc cttgctgcga tgatctttgg gaaatggaat ccaatcggtg ctatgctttc
    11341 tagtctcttc tttggacttt cacaaagttt ggctgttatc ggttctcaat tgccgttcct
    11401 acaaggagtg ccagcggttt atcttcaaat tgcaccttat gttttgacaa ttcttgtctt
    11461 agcagccttc tttggaaaag cagtcgcacc aaaagcagat ggtatcaact acatcaaatc
    11521 aaaataagca tacaaaaaaa cgtcagtcca atgactgaac tgccccccaa aagttagaca
    11581 gaaaaaatct aacttttggg gtgtttttat tatgaaa
//
LOCUS       DAVAGB010000056        11264 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVAGB010000056 DAVAGB010000000
VERSION     DAVAGB010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11264
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.057"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(116..391)
                     /locus_tag="VQO19_001824"
     CDS             complement(116..391)
                     /locus_tag="VQO19_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HET1350045.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(498..1337)
                     /locus_tag="VQO19_001825"
     CDS             complement(498..1337)
                     /locus_tag="VQO19_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET1350046.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILCHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1479..2327
                     /locus_tag="VQO19_001826"
     CDS             1479..2327
                     /locus_tag="VQO19_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET1350047.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2420..3337)
                     /locus_tag="VQO19_001827"
     CDS             complement(2420..3337)
                     /locus_tag="VQO19_001827"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HET1350048.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3775..3980
                     /locus_tag="VQO19_001828"
                     /pseudo
     CDS             3775..3980
                     /locus_tag="VQO19_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4185..4478)
                     /gene="rpmA"
                     /locus_tag="VQO19_001829"
     CDS             complement(4185..4478)
                     /gene="rpmA"
                     /locus_tag="VQO19_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HET1350049.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4495..4839)
                     /locus_tag="VQO19_001830"
     CDS             complement(4495..4839)
                     /locus_tag="VQO19_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HET1350050.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4855..5169)
                     /gene="rplU"
                     /locus_tag="VQO19_001831"
     CDS             complement(4855..5169)
                     /gene="rplU"
                     /locus_tag="VQO19_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HET1350051.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5205..5292)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5357..6055)
                     /locus_tag="VQO19_001832"
     CDS             complement(5357..6055)
                     /locus_tag="VQO19_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HET1350052.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKA"
     gene            6457..6756
                     /locus_tag="VQO19_001833"
     CDS             6457..6756
                     /locus_tag="VQO19_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HET1350053.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            complement(7156..8130)
                     /gene="pta"
                     /locus_tag="VQO19_001834"
     CDS             complement(7156..8130)
                     /gene="pta"
                     /locus_tag="VQO19_001834"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HET1350054.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(8174..9070)
                     /locus_tag="VQO19_001835"
     CDS             complement(8174..9070)
                     /locus_tag="VQO19_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET1350055.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(9067..9885)
                     /locus_tag="VQO19_001836"
     CDS             complement(9067..9885)
                     /locus_tag="VQO19_001836"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HET1350056.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLEKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIAHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(9869..10540)
                     /locus_tag="VQO19_001837"
     CDS             complement(9869..10540)
                     /locus_tag="VQO19_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HET1350057.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            10668..11237
                     /locus_tag="VQO19_001838"
     CDS             10668..11237
                     /locus_tag="VQO19_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HET1350058.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQIKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
BASE COUNT         3519 a         2343 c         1946 g         3456 t
ORIGIN      
        1 atacaatatt ttcggaacat tcaacttttt aactctattt attactagat ttcataatta
       61 aaaagcctac tgaccaagct agaaagcttg atacaatagg ctttttaaag actgattatt
      121 taacagcgtc tttaagagct ttaccagctt tgaatgctgg tactttagaa gctgcaattg
      181 tcatttcttt accagtttgt gggttgcgac ctttacgttc tgcgcgctca cgaacttcaa
      241 agttaccaaa accgatcaac tgaacttttt caccagctgc aagatagtca gctactgctg
      301 caaatacagc ttcaactgct gctgctgagt ctttcttagt caattctgta gcttctgcta
      361 ctttagcgat caaatcttgt ttgtttgcca tgttaatgat tcctccaaat aatttctaat
      421 taacaaatat aatcatatcc taaaatccct tttaggtcaa gttaaaaacg ctatttcttc
      481 ccattttatt tattttttta ggagtggtaa cgtatcaaaa tagcccaagc gttctcaccc
      541 gtgtgagttt gaataatgga acccgtttcc aaaacagaaa ttggcttttc aacataagct
      601 tgtaagcttt ctttcatctc ttttgcccaa tcatcactac cagaatatga aattccaatc
      661 tctgctacag cacgttcaga aagcgatgtt atcaactcat ctaaccattt tttaaatgtt
      721 ttagttccac gacctttaac cattggctgc aattcatggt ctttcatttg catgacaaca
      781 cggatattga gaagagagct caacaagcca gttacacggc taattcgtcc acctttgaca
      841 agattttcca aagttgaaac accaatataa agctctgtat ggtttttaac ctcttctaca
      901 tgacataaaa ttgcctccat atctttacct tcttgagcta acttcgcagc ctcaacaact
      961 tggaatttca gggcttggtc agtgaaggaa ctatcaacaa cagtcacatc tgcagtagat
     1021 aggctagcac cttggcgtgc tgcttctacc gtacccgaaa gagcatggga catatgaata
     1081 gcaagaatct ggccaccatc tttgcatagg tcttcaaaaa tctcagcaaa gacacctaca
     1141 ggtggctgac ttgttttcgg aagattctta ctttcttgca tcaactgaag aaatttacct
     1201 tcttctttca aatccgcatc agaataaaca acattatcaa tcattacaga taatggaaca
     1261 attgtaatat ctaattgctt tactagttca ggttcaatag taacagatga atcggttaca
     1321 atcttaattt ttgtcatagt atcaatcttt ctattttagg attcagattg gtttccttac
     1381 ttctaattat atcaaaaaaa agattaaaaa tcctaatgga gtcaatcaaa ttttccgtaa
     1441 aatttgatat aatcaactta taagaaaaga ggtgtcctat gattaaaaaa atttacccca
     1501 tttttaccat tttactaggt gctgctattt atgcttttgg actgacttat tttgtagttc
     1561 cccatcatct ctttgaagga ggggcgacag gtattaccct catcacattt tatcttttta
     1621 aaatccctgt ttccctcatg aacctgctga ttaatattcc ccttttcatc ctagcttgga
     1681 agatctttgg agccaaatcc ctctattcta gtttactagg aaccttagct ttgtccggct
     1741 ggttagcttt ttttgagcat attccccttc atattgatct tcaaggtgat ttactaatca
     1801 cagcccttat agcgggaatc ctattgggaa ttggccttgg aattattttt aatgctggag
     1861 gtacaactgg cggaactgat attctagctc gtattctcaa caaatacact catatatcca
     1921 taggaaaact gctctttatc ttagattttt gtattctcat gttgattctc ctaatcttca
     1981 aggatttgag attggtttcc tacacgcttt tgtttgattt tattgtttct cgtgttattg
     2041 atttgattgg tgaaggagga tatgccggca aaggctttat gattatcaca aaacgtcctg
     2101 accaacttgc taaggcgatt aatgatgacc tcggaagagg tgttactttt atttctggtc
     2161 aaggctacta tagtaaagaa aatttgaaaa tcatctactg tattgtcgga agaaatgaaa
     2221 ttgtgaaaac gaaggaaatg attcatcgaa tcgatcctca agcctttata actattacag
     2281 aagcccatga aatcctagga gaaggcttca cctttgaaaa agaataaaaa gaggtaatgt
     2341 cgtgacctca aaagttagac taaatcatct atcttttggg ttacagacaa cctctttttt
     2401 attttattta ctcaagctct taagaccaat tccgagttac ttcttcatca gcctttaact
     2461 gatccactaa ttggtcaact gagtcaaatt tggtcatatc acgaatgcga tcaagccaat
     2521 aaaccatgac ggtttcccca taaatatctt gattaaaatc aaaaatattg acttcaaaac
     2581 gtgcttcttc tccatcaaag gtcacatttt tcccgacact agccatagca cgatacttct
     2641 gtctttgaat ctcaacatca acgacataaa cgccatctgc tggcatataa gtacggtcta
     2701 aaagcactaa attcgctgtc ggataaccaa ttgtacgacc acgagcatta ccatgaacca
     2761 ccatacctct tgatggaagc ggtgccccca aaagttttcc tgcttctttc acatttccat
     2821 ctaaaatagc ttgacggata cgagttgaac taatctttcc tttctcatct tctacaggtg
     2881 gaacaatgat aacttctcca tcaaagtaat cctttaaatc ttctgctgtt tttttgtcag
     2941 aaccaaatgt ataatcaaaa cctgcaacaa taattttggc attcatagcc ttgatataag
     3001 ttgcaaaaaa ttcttgtgca gtgagactag cgaattgact actaaaatca aggagatata
     3061 attcttctac accttcgcgc tttaattttc tttcacgttc agcagggttc aaaatatgca
     3121 aaaacaaatc tggatgataa ggctctaaag cgatctttgg agattcatta aaggtcataa
     3181 cgacgatagg taataaatcc tttctcgcag ccttgttggc aacacgaaat aattcttgat
     3241 gccccttatg tatgccatca aaatagccga gaacaacgac tgaatcagat ggtgtgccaa
     3301 tatctttttg gttttttata ggaatagtaa taatcataaa ataattatat catagcgata
     3361 gctatttctg gaacagaaaa tctgaaatgt tgtttttttc acatgaagtg tacctgtttt
     3421 caaaaagcac tttattctat cgttgcttaa ctatgaactt tgcaatattc ttctcaaaaa
     3481 cttgtaggac atcttcaaaa ttttgcaagg agtgattaga cttgttcggt aaccataaag
     3541 tgtcatacta tgcttatgta tgaaaaagca atgcaactaa ctcctgagaa ctttaaatta
     3601 ctaattggtg ccgaaaaggt agaatttaga atcgaggtac acctatggct gtaaaattta
     3661 caaaatgaga caacttgggc aagatgtttg aagaatttcc taaactccct gatttgaagc
     3721 aagtcacttt ccctgatgac aaagaaaaaa gccaaaacag caaagaaaaa ctagatgact
     3781 gctttccaac aactcccatc tagtgtgctt cagactgggc tatttttctc tccatctgtt
     3841 agcttggatt ctcagacagt ttcagctaaa gaatatcttt tcccttatca gaaggaacgg
     3901 ctcaaaccat tcagacaagt gaagggacga caagccaata tttgaaacca gatagcagtt
     3961 cttatagtca attgaaataa aatctgaaga aatcgagtag gaaactcata tcaattttta
     4021 acagtgttct attccagatt caatccacta tacatattaa aaagtatggg taccaaaaca
     4081 aaaaaacagg ctctccgaaa actcggaaag ccttatttta agctgtttct agcttcctca
     4141 cctttacatt tcaaggttcg ggataaaagg ttcaatggac ctttttattt agcgattggg
     4201 taaacagaaa cttgtttttt atcgcgtcct ttacgttcaa agcgtactac gccttcaact
     4261 ttagcgaaca aagtatcgtc tccaccacga ccaacgttta cacctggata gatgtgtgta
     4321 ccacgttgac ggtaaaggat tgatccacct gttacagttt gtccgtcagc tgctttagct
     4381 ccaagacgtt ttgcttgtga atcacgtccg tttgatgtag aacctccacc ttttttgtgg
     4441 gcgaaaagtt gcaagttgtt aagagtcatt tttaacataa tgttttcctc cgtgttagtt
     4501 ttctgtgata actctggttt ggacgaactc agaatagttc tccgataagt ttgccatacc
     4561 taagaaaaat gattcaaaga ataactgggt catttctctc tggtgtgaag gaagatcttt
     4621 tggtatttca accatcagat agccaccttc atcttcgttt aattctagga ttggttcata
     4681 gcctgcaaat ttctcaatag aattgataaa gttaatggca agcgtagaaa ccgatgcaca
     4741 cacgacatct aagccgtatt cgccactctc ggcgtgtcca gtaatttccg cactcctcag
     4801 ctcgccatct tcggctctct caaagactgc ctgtatcatg tgttctcctt aaaattaagc
     4861 gttgattgcg ttgatgacaa cttttgtata tggttgacgg tgaccttgtt tacggtggct
     4921 acctttttta ggtttgtact tgtaagtaac cactttcttt tgttttcctt gtttttcaac
     4981 agttccaact acagtagctc cagcaacaag tggagttccg acaacagtat tttcaccacc
     5041 aacaagaaca acttcgttaa aagtaacttc ttgaccagct tcaacgttca atttttcaac
     5101 gtaaactgct tgaccaactt caactttaac ttgttttccg ccagttttga taattgcgta
     5161 tgtgctcatt atgcacctcc tatgattttt atgggtttcc ccgatttttt gtgaagactc
     5221 gcctagcatc gtgggacgaa ccacttaaac ttgaataatc aagcaacgat gttcgtgcgg
     5281 ttgcacagga tcgtgcatag tcaactcttc aagtatagca tatctcctat tttcttacaa
     5341 gtaataacac ctaaaatcaa gctttttctt ttactttttt ctgccaagag gcaaaaagca
     5401 tgctgaggta aaaaacgctc atcataatag gaacaccaag aatggtcttt tcatgataga
     5461 aaatcgtcaa ataggctgaa aagacaacgc caaggacaaa actactaagc aggctaacaa
     5521 atatgaatcc ttcacgcaaa aaaggagtgt gcttggttcg gaaataatct ccaaaagcca
     5581 gcatggtccg tttgatattc cctgtcataa aagcgttatt ataggcaata cccgacactt
     5641 ctccaaaagc agttgtcacc agtcccatac agaaggccaa gggcggcact agatagatat
     5701 tatccacagt ttgcggcaca aaagcaataa tgattgataa gattgccaag ggaatcaagg
     5761 acagaatagg ttttttcaca attctcaatt tttccttata aatcgttaat aaaaagactc
     5821 ccatcataaa cgctagcaag gtgagaacct tgtccctaac atccgaaaca ttatttttaa
     5881 ttaattctac tgaaagaaag acaacatttc cagtttgtcc agctacaagg gtattcccgc
     5941 gaacaataaa agtgtaagca tccacatatc cagcacaaaa cgtcaaaaaa agtgctaacc
     6001 ttttagactg acgtgatatt tttcttatag gtaataacct cattttccct cccattgtat
     6061 tttctcttag aaatattgta ccatttcttt ctaaaaaatc gtagactacc atttagattt
     6121 tactattagc ataaaaataa taatagacaa ctatttatcc aaaaatagat agaggtaaca
     6181 tgtttgcaaa caaagcatac gaatctttag taaaatcatt tccatgaaac tagaatagag
     6241 cccctcttag caaaaatcat tattttaatt tatttctaat cactccttga cataaataac
     6301 tctcaccaat aaaagactat gtcttaaaaa aatggtataa taaaatcaat acttgggctt
     6361 gatggctatg ctactaataa caattaggag agaaaatcag gcacttgtta acaacaagga
     6421 ttatcccctt gagatgaaag gaactttaga aatcttatga tgaacatgca aaacatgatg
     6481 cgtcaagcac aaaaacttca aaaacaaatg gaacaaagcc aagctgaact tgctgctatg
     6541 caatttgttg gcaaatctgc tcaagatctt gtccaagcga ccttaactgg cgataagaaa
     6601 gttgtcagca ttgatttcaa tccagctgtc gttgacccag aggaccttga gactctttct
     6661 gatatgaccg ttcaagccat caactctgct cttgaacaaa tcgatgaaac taccaagaaa
     6721 aaactgggtg ctttcgctgg gaaattacct ttctaaaaac aaggagctag aacaatgctt
     6781 gtcgataaca aaggctaaga aaggtgcaaa aatgactcta taatatttgt agtgggtaaa
     6841 tccactatag atattatgga gcctatttta ttgtagaaaa cgcataatag caggtgtcaa
     6901 gacacttaat attatgcgtt ttctcatgaa aaaattctct tttcatactc atttaaaatc
     6961 aaaaagggaa attatcgttt tacggacata catattacag atttctatag gtcgtgtata
     7021 gacaggatat catcgcttgg aagttttcct ttttgacacc aatcagtaat ttagttctca
     7081 ggaattaatg gcagtgcttt tcgtacatag tttcataact acagtatagc atagtatatc
     7141 gctttatagt tttcactatt gatgaactgc ttgagctgct gtgatgaggg tcaacttgta
     7201 aacatcatct gcattacatc cacgagaaag atcattaact ggcttgttta aaccttgcaa
     7261 aacaggtcct acagccgcaa agccacccag gcgttcagcc atcttgtaac cgatatttcc
     7321 tgcctcgata cctgggaaga tgaagacatt tgcttgacca gctaccgtac ttccaggagc
     7381 tttcagagct gcagtttcag gaacaaaggc tgcatcaaat tgcaactcac catcgatttc
     7441 aaggtcagga cgcaagtcgt gagcaatttt agttgcttca acgaccttat caacgctttc
     7501 accaaaccct gaacctttag tagaatagct caacatggca attttaggtt cgatgccaaa
     7561 catcttagct gtgattgctg agttgatggc aatttcagcc aaggcttctg catctggatt
     7621 gatgttaatg gcacagtctc caaataggta acgttccgta ccacgaacca tgaggaaggc
     7681 tcctgaagta cgagttacat ttggacgagt tttgatgatt tgtagagctg gacgaactgt
     7741 tgaagctgtt gagtgaatcg ctcctgacac cattccatca accaagccca agtaaaccaa
     7801 catcacacca aagtagttga catcttcaac caaaaccttg cgtacatctt cttcagtcat
     7861 tttgcccttg cgacgctcca ccaaggcaga aaccatttct tcaaattgag gataatgttg
     7921 agggtcgatg acctcataac catccatgat cccttcaatt tcaagataaa ttttaatttt
     7981 ttcaggattt cctaacaaaa caggaatcac ttctgtttct tttaccaaac gtttagtcgc
     8041 ttgaagaata cgtggctctt ccccttcagg gagaacgata cgagcatttt taccaacaag
     8101 gttggctttg agactttcaa aaacttccat gagttttctc ctttaagata ataattatac
     8161 tctgagacag tttttataga gtattagttg ataactgggt aataaggtta ctgaaatcat
     8221 ccggcaaggg actttctaac tgcaagtctt gctctaaaaa tggatgataa aaggataggt
     8281 aatggcaatg cagagcctga cgttgaatac catcttccag actaccacca tacaaatcat
     8341 ctcccagcaa aggaaaaccg atatgagaaa aatggactcg gatttgatgg gttcgaccag
     8401 tgtgcaggtg aatatagacc aagtgaatat ttccataaga agctacaatc ttgtatgaag
     8461 tatgggcata ctttccgcct ttagccactc gtctggtaat aatggaatct tcatcacgcg
     8521 caatcggagc aataatttcc ccttctggct ccaaatgtcc atctccctta accaaagcaa
     8581 agtagcgttt ctcgatagat ttcttctgca actgcttgtc taatcgtgca tgggcataac
     8641 cgtgcttggc aaagagcatc aagccagaag tgtccctatc tagtctggta acaatgtgaa
     8701 cctgctgatt ttcataattt tgcttgacat agtaaccctt gataaaattg gcaatggtat
     8761 tagagtgatt aacactagga atagaagcca ctccataggg tttattcaag actagaaagt
     8821 ggtcatcctc atagagaata tctaatggaa gctcaatagc ctccaaggtt tcaaagcctt
     8881 tctcagcggg aatgtcaatg gtaacgtagt ctccaacgtc caatagatac gttgcatttt
     8941 gcggttgatt attgaccaga atagctccac ctcgaaactt aatcttggcc agcaatccct
     9001 tagaaacctc gtgctttttt aagaaggtct taaccttgac atgttcatct gcgataaatt
     9061 caaacctcat tcatccacct caccgataaa ggcatcctta acacggttcc agaaactggt
     9121 atggctagga gtcgcgacaa agtgaatctt atgatgggcg atttgatact caatacgctc
     9181 aatattacgg aaagaataaa cgctattgtc aaccgaaata gtatgataat cgtttcttgt
     9241 tggaataagt tcaatcttat ccttcttagg cacaataatg gaagagccca gtgttcgata
     9301 gacacgatta ttaaggctgg caatttccgt taattgcaaa gcttcaatgg tagggtgtaa
     9361 aacagcaccg ccaagagact tgttataggc agtactacca gtcggtgtcg aaactgttag
     9421 cccgtctcca cgaaaacgtt caaagggaac accatttatt acaatatctg ccaccatggt
     9481 tcgatcagac ctgcggatgc tggcttcgtt gagtgctctg aaaatcttaa cttcaccatt
     9541 ttcaagaaag accttcacat tcagaacagg gtaagaaacc cttgccccag tatctagctg
     9601 caaattagtc actagcttgt ccaactcaaa atcacgataa tctgtataga agcccaaatg
     9661 tccagtgtga agaccgataa agcggacctt ctcaagctga ttttcgtact tatgaaaggc
     9721 cgacaagagc ataccatccc cgccaatgga aatgacaata tccggattgg tatcattgag
     9781 tataaactga tttctcttca aacgatctcg caattcatac aaaacccttt gactctgcgg
     9841 ttttctattg gctatcagat caattcgttt acctgtattc ttcatctgta tcgtcactgt
     9901 ttcctacacc gtcatttaat tttctactca aaggatcaaa aagtgcctgg gcttcttgga
     9961 tatcatcacg aatttcaccc atttcttcat ccaactgatg ggcgattcta gctgtaattt
    10021 ccagtcgctt cttaatctca tctgggaaat ccccttggta cttgtagttg agagaatgtt
    10081 ctatcgttgc ccagaaattc atggccaaag tacgaatttg aatttctgcc aaaatagtct
    10141 tagctccatt gatggtatca accgtatatt ctactaccac atgataggaa cgatagcctg
    10201 atgcttttct atgagtaatg taatctcgct cctgtatgat tcgcatatcc tgacgcttgt
    10261 gcaaaatatc cactacttcc ttgacgtcat ctacaaactg aaccatcaca cgtaagccag
    10321 caatatcctg caaatcgtgt tccaaggtcg cataagtaat gccacgacga gccatttttt
    10381 ctttgatgct ctcaattggc ttgactcgac cggtcacaaa ctcaattgga gaatgcttat
    10441 tttgcttacg atattgctta cgaataccac gaagtttaat ctttaactca ccaacagctt
    10501 gaatgtaagg atctagaaat tcttcccatt ctaaggtcat atattctccc ttgttctcat
    10561 attatccgtc aaaaatatct ttgatttttt ctccagattc atatacaata aatacaatgc
    10621 ttattatacc ataaatccgc tttcaacgat aaaaaaaggt aagaaaaatg aaacatttag
    10681 aaattgaatt gaaaacacta ttgaaaaaag atgaatacaa tcgtctaaaa gaccagttca
    10741 caggtgtcac tcctgttctt caaacaaatt actacatcga cacgcctgat tttgaactgc
    10801 gagaaaagaa agtcgctatg cgcattcgaa cctttgaaga ctgggctgag ttgacactca
    10861 aagtcccgca gagtgttgga aacatggaat acaaccaaaa attgcaacta aaagatgctg
    10921 agaactatct gagtaaggaa gaacttcctc aagggctagt actggatgaa ttggcgaaac
    10981 atggtatcca aattaagaac tggcaggttc ttggttgtct aacaacgctt cgctatgaaa
    11041 tgaaaacagc tattggtctc atggcactgg atcagagccg atactttgat atgacagatt
    11101 acgaattgga gcttgaagtg gaaaatcatg agcaaggcaa acaggatttc cgacaatttt
    11161 tagagaaaaa tcagatttcc taccaaaaag ctccttcaaa attggttcga tttgtcaaaa
    11221 gtatgaaaaa tagctgaaat aatctccatt ttttggtaaa atag
//
LOCUS       DAVAGB010000057        11003 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVAGB010000057 DAVAGB010000000
VERSION     DAVAGB010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11003
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.058"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            76..1335
                     /locus_tag="VQO19_001839"
     CDS             76..1335
                     /locus_tag="VQO19_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HET1350059.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHIHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1411..1546
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1585..2085
                     /locus_tag="VQO19_001840"
     CDS             1585..2085
                     /locus_tag="VQO19_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HET1350060.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2161..2529
                     /gene="rplL"
                     /locus_tag="VQO19_001841"
     CDS             2161..2529
                     /gene="rplL"
                     /locus_tag="VQO19_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HET1350061.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            2716..2886
                     /locus_tag="VQO19_001842"
     CDS             2716..2886
                     /locus_tag="VQO19_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350062.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            2886..3134
                     /locus_tag="VQO19_001843"
                     /pseudo
     CDS             2886..3134
                     /locus_tag="VQO19_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            3148..3488
                     /locus_tag="VQO19_001844"
                     /pseudo
     CDS             3148..3488
                     /locus_tag="VQO19_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3481..3861
                     /locus_tag="VQO19_001845"
     CDS             3481..3861
                     /locus_tag="VQO19_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET1350063.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            3874..4017
                     /locus_tag="VQO19_001846"
     CDS             3874..4017
                     /locus_tag="VQO19_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350064.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            4110..4697
                     /locus_tag="VQO19_001847"
     CDS             4110..4697
                     /locus_tag="VQO19_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET1350065.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGIGFVSLLIISLCFSLIHAQESTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWSLLVYSLLLF"
     gene            4899..5036
                     /locus_tag="VQO19_001848"
     CDS             4899..5036
                     /locus_tag="VQO19_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HET1350066.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            5326..6729
                     /locus_tag="VQO19_001849"
     CDS             5326..6729
                     /locus_tag="VQO19_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HET1350067.1"
                     /translation="MNNDEWVYQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICH
                     EMRIPFKHLSTEDKFIMRNGKLVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGP
                     YILSDKRWDEAPIYLRYGVFRPSRDDEKKVVIDELIVGDEVVKDERLPVFKIPKGIVP
                     PDFLNKWLDKKDKKQGDFPFIIDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLG
                     FDGTYSSERLASECKALKILNEWSEMPKIYWYGKIWEHTFLGIEHMKGVPLNRWVTNN
                     FPLYEVVDKTKDYLLRVSKIVEKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIID
                     WEQAVFSNDEKVVHKVAAPGFRAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNY
                     VSQTRIEGKKLFESLGYTREHIDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIE
                     SEQDIQDFIIKAFLLVN"
     gene            6918..7538
                     /locus_tag="VQO19_001850"
     CDS             6918..7538
                     /locus_tag="VQO19_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET1350068.1"
                     /translation="MKDVVYSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLIN
                     GSLKPQKGYVNLLSHGKKSSDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVL
                     KKVNLYEELEKIDILNYKCGENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDN
                     DNSNSIHDILFNLGISFIEVSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            7553..8293
                     /locus_tag="VQO19_001851"
     CDS             7553..8293
                     /locus_tag="VQO19_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1350069.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            8296..9615
                     /locus_tag="VQO19_001852"
     CDS             8296..9615
                     /locus_tag="VQO19_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET1350070.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASRLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYCKSY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDILIDDMNLLGLILPNFIVSIILFILIFITKSSYFIFKNAKIIS"
     gene            9748..9885
                     /locus_tag="VQO19_001853"
     CDS             9748..9885
                     /locus_tag="VQO19_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HET1350071.1"
                     /translation="MAAEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            10141..10374
                     /locus_tag="VQO19_001854"
     CDS             10141..10374
                     /locus_tag="VQO19_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET1350072.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQILDLDYEDLFRR"
     gene            10377..10964
                     /locus_tag="VQO19_001855"
     CDS             10377..10964
                     /locus_tag="VQO19_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET1350073.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQVLYGASLFS
                     FLWMYGQRKQVVKVNMKTRMKCLGIGLASLLIISLCFSLIHAQGSTNQTNLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALVHHPGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNFLVYSLLLF"
BASE COUNT         3606 a         1593 c         2216 g         3588 t
ORIGIN      
        1 aaccacacct acggcaaagt gaatctgaag tggtttgaag agagtacaac ttgtctttta
       61 gaaaaggagc ctataatgaa agtctttcag catgtaaata tcgtgacttg tgatcaagat
      121 ttccatgttt atcttgatgg aatcttagca gtcaaggatt ctcaaatcgt ctatgtcggt
      181 caagataagc cagcgttttt agagcaagct gagcagatta tagactatca gggagcttgg
      241 attatgcctg gtttggtcaa ttgtcacatc cattctgcaa tgacaggtct gagagggatc
      301 cgagatgaca gcaatctcca tgaatggctc aatgactata tttggccagc agaatctgag
      361 tttactcccg acatgactac caatgcggtc aaagaagccc tgacagagat gctccagtca
      421 ggaacaacaa cctttaacga tatgtataat cccaatggtg tggatatcca gcaaatttat
      481 caggtggtga aaacttccaa gatgcgttgt tatttttctc cgactctctt ttcttcagag
      541 acagaaacaa ctgctgagac tataagtaga actcgatcca tcatagacga aatcttaaaa
      601 tataaaaatc caaatttcaa ggttatggta gcacctcatt ctccgtatag ctgcagtaga
      661 gacttgctgg aagcgagttt ggaaatggca aaagagctaa atattccgct ccatgtccat
      721 gtggcggaga ccaaggagga gtcaggaatt atcctcaaac gatacggcaa acgccccctt
      781 gcttttcttg aagaactggg ttatttagat catccgtccg tatttgctca cggggtcgaa
      841 ttaaacgaga gagaaattga acgcttggca tcttctcaag tggctatcgc ccacaatcct
      901 atcagtaacc tcaaactggc atcaggaatt gctccaatta tccagctcca aaaagcggga
      961 gtagcagtcg gaattgcgac tgactcggtt gcttccaata acaatctaga tatgtttgag
     1021 gaaggaagga ctgcagctct tcttcagaag atgaaaagtg gggatgccag ccagtttcca
     1081 atcgaaacag ctctcaaggt actgacaatc gaaggggcta aggtccttgg aatggaaaat
     1141 cagataggaa gtctggaagt cggcaagcaa gcagattttc tggtcattca accacaaggg
     1201 aaaattcatc tccaacctca ggaaaatatg ctgtctcacc tggtttatgc agttaaatct
     1261 agtgatgtag atgatgttta tatcgccgga gaacaggttg ttaagcaagg tcaagtcctg
     1321 acagtagaac tttaaaagaa aaattacgaa aaattttaaa aaaagtttgc aaaaatcttg
     1381 cattcttttt ttgactatgc tatacttata tacggtttaa aaaaactgcc taagacagta
     1441 ggggagctcg actcataaat atcctaccga ggacaaaacg tatcatgtaa aaagaagcgt
     1501 attgtacttt cgtgtctagg tttgggcgcg tttttctttt tgaaaaattc cccaagcaaa
     1561 ataattacgg aggtgaacac actaatgagt gaagcaatta ttgctaaaaa agcggaacta
     1621 gttgacgtag tagctgaaaa aatgaaagct gctgcatcta tcgtcgttgt agacgctcgt
     1681 ggtttgacag ttgagcaaga tacagttctt cgtcgtgagc ttcgtggaag cgaagttgag
     1741 tataaagtta ttaaaaactc aatcttgcgt cgtgcagctg aaaaagctgg tcttgaagat
     1801 cttgcatctg tatttgttgg accatctgca gtagcatttt ctaatgaaga tgttatcgca
     1861 ccagcgaaaa tcttgaacga cttttctaaa aacgctgaag cacttgaaat taaaggtggt
     1921 gcaatcgaag gcgctgtcgc atctaaagaa gagattcttg cacttgcaac tcttccaaac
     1981 cgcgaaggac ttctttctat gctcctttct gtacttcaag cgccagtgcg caacgttgct
     2041 cttgcagtca aagcggttgc agaaagcaaa gaagacgcgg cttaatctta agctatacag
     2101 cgtagcctag ctacgaaaaa aactattata aaatttaaaa cttatttgga ggaaataaca
     2161 atggcattga acattgaaaa cattattgct gaaattaaag aagcttcaat ccttgaattg
     2221 aacgaccttg taaaagctat cgaagaagaa tttggtgtaa ctgcagctgc tcctgtagct
     2281 gttgctgcag ctgatgcagc tgatgctggt gctgctaaag attcattcga cgttgaattg
     2341 acatctgcag gcgacaaaaa agttggcgtt atcaaagttg tacgtgaaat cactggtctt
     2401 ggtcttaaag aagctaaaga acttgttgac ggtgcaccag cacttgttaa agaaggcgtt
     2461 gcaactgcag aagctgaaga aatcaaagct aaattggaag aagctggagc ttcagttact
     2521 cttaaataat agagtatcgc aatttgattg cggaatccct atttaccagt ctttgagagc
     2581 gataagcgat tgatagaaac tgataaattg atttggtttc ctgccaaaaa ttctttggca
     2641 ggatttttgt tttaataaac tttcgggggt agacactaga ttgtctaccc ctttttttgt
     2701 gtttcggagg taattatgca aaaggaagga cagtcatcac gtcaattcgt gaagagtcat
     2761 ctcatgacta tcatgggagt tgatattgta aaagcaactc agttagttga tgaaatggaa
     2821 caagtaggtt taatccgatt tgatgaattt ggaaatgttg gaattttagt cttggaggga
     2881 caataatgaa gcgtattacc gctaatcaat atcagacatc agagcgttat tataagctcc
     2941 ccaaactttt atttgagagt gaacggtata agaatatgaa actggaggtt aaggtggttt
     3001 actcagtttt aaaagatcgg ttggagttgt ctttgagcaa aggttggatt gatgaggatg
     3061 gggctattta tttgatttat tccaattcaa atttgatggc acttttaggc tgttcaaagt
     3121 caaaattact ctccatgtga gtttgaagtg acatttttag atgattacca taaaaaacat
     3181 aactacccac tattttacga atcctatctt caaaacgtta tggaattcct tgaaagtcaa
     3241 gacataaaga atggggttga tgcctttgta gatgatcatc aaaatctcgt ttttgtttta
     3301 tatggacaag gctatcgagc cgagggaaaa gagggaatac ttacaaccca agtaactgta
     3361 aaagcttatg atgaagacaa gaaaccgatt aacttcgcaa atttattaga ttccttaatt
     3421 tattagattc cttaatcgtg tcagaatatc aaatggaacc gaatctttgg gaggtctccc
     3481 atgattgatc tctatctaag taaaaataga caaagaaatc aacttctttt agatttcttc
     3541 caaaactatg gcatagaggt atcttgtcat tcagtttctg aaatgacaaa ggacaaatta
     3601 attgagatga tgagctattc ttcagattgt tttgagtttt tatctcccaa tttattacga
     3661 tttaagaacc gtgacaatct aagattaacg gatttcgttg agataatttt aaaaaatcct
     3721 gaactaacca tcagacttcc tcttgcggtt tcaaataagc gagtttatcc aagtctgaat
     3781 ttggaagagg ctagagctct attgccaaga gatacgaaac aattgattta catggcgcaa
     3841 acacattatt tatctaacta aaggagaagc aatatggctg aacgattttg ggagaacttg
     3901 tccattattt tggctgaaag aaatatcagc tggattgagt taaccagaaa aatgtttgcg
     3961 ggagagtttc actatccaag tgaattgaat cgtttgtatc aaaagattcg ccactagaag
     4021 atggaacaat gaatgcctca aagtccatgg gtagaaagga ttgtgcaggt attagattta
     4081 gattatgaag atttatttcg gaggtaacta tgaaaagaat aattccagtt tatatattcc
     4141 aacaagtaaa tgtcctattg gtatctctat acttattgaa atttctttgt atcggtgagt
     4201 taactatact acagattctc tatggttcgt cactcatttc ttttttatgg atgtatggcc
     4261 aacgcaaaca agctcataag gtaaatatga aatctaggat gaaatggctt ggtattggat
     4321 tcgttagcct actgattata agtctatgtt ttagcctaat ccatgcgcaa gaaagcacga
     4381 atcaagcaaa cttaattgga cttcaacatc aagttccttg gttttcattt ttattgtttt
     4441 taatcaatgc gagtatggtt gaagaatttc tgtatagaga aattttatgg aacttggtta
     4501 gaaaattaga tattcgagtt gctttgacaa gtgttttatt tgccttagca catcatccag
     4561 gaaccattat agcttggtgt ttgtatgtat cgctggggat gtttttaggg cttgtacgct
     4621 acaaattgga cttatggggc agtatggggc tacatttggt gtggagccta ctagtttata
     4681 gtttgctgct tttttaaaat aggtaacctg atttttaggt aacttctaaa actaacttcc
     4741 agttttggga gagagatgga agttactttg aaaagttacg gaaacattat tttctacgtg
     4801 acaacattgt atcattgctt gcattttact gctggagaga gtataatgaa ggtggataaa
     4861 gcacttaatc ccaaaaattt aaataggagg agttagctat ggcagaagaa gtattaaatc
     4921 ttcaattagt atctgttcaa gttgacgaaa cagatgaagt tgatggaatg cgatttagta
     4981 cattcagtac aaaccgttgc ggtaactgga gtgcttttag ttgggaaaat tgttaattca
     5041 tttaaattgt aaactttagg gattctctgg agttatggat ctcgttccaa tatgtgcacg
     5101 ttggaatgtc agtgcttata tggggggaat ccaaaggatt ctcccttttt attttaataa
     5161 gtctgtctag ctatagatat attaagtttg atagaatttc ttggagattt tgttatggat
     5221 tataatttca atttggagca tcctttcttt ttcactaata atgattatag tacagatact
     5281 agcataaagt actaagtaag tctgcctttt aattggcacg aagtaatgaa taatgatgag
     5341 tgggtttatc aataccctat tggaaaattt gttgaaagac aagggtggaa aatacacatt
     5401 agttcagagt ataatagttc acacgaattg ttacaagatg tagcaaaaat ttgccatgaa
     5461 atgcgaattc catttaaaca tcttagtaca gaagacaaat ttatcatgcg aaacgggaaa
     5521 ttggttagtc gaggattttc tggtaaattt attacatgtt atccaaatca aaatgaatta
     5581 gagtcggttt tgcaaaggtt agaaagtgcc ttaaagcaat ataatgggcc atatatttta
     5641 agcgataaac gttgggatga agcaccaata tatctgaggt atggtgtgtt taggccgtca
     5701 agggatgatg aaaagaaggt tgttattgat gaattaattg ttggcgatga agttgttaaa
     5761 gatgaacgtt taccagtatt taaaattcca aaaggtatag tgccccctga ctttttgaat
     5821 aaatggcttg acaagaaaga taaaaaacag ggagactttc cctttattat agataatgca
     5881 attagatttt caaacagtgg tgggatatat aatgctagac taaaagaaga tgggaaaaaa
     5941 ataattttaa aagaggctag accgtataca ggtctaggat ttgatggtac ttattcttca
     6001 gagagattag cttcggagtg caaagcacta aaaattctaa atgaatggag tgagatgcct
     6061 aaaatatact ggtacggtaa gatctgggag cacaccttct taggaattga acatatgaag
     6121 ggcgttccac taaatagatg ggttaccaat aattttcctt tatatgaagt tgttgataag
     6181 accaaagatt atctattgag agtttcaaag atagtagaaa aactcatcga tttaacgaat
     6241 aagtttcatt ctgaaaatgt atatcatcaa gatttacatt taggaaatat cttggttaag
     6301 gatgaagatg agattagtat aatagactgg gaacaggctg tcttttcgaa tgatgaaaaa
     6361 gttgtacata aagttgcagc ccctggtttt agagcatggc gagaaacact tcccagtgag
     6421 atagattggt atggtattag acaaatagct cattatttat acatgccact agtaactaca
     6481 tcggatttga catacaacta tgtaagtcaa accaggatag aaggaaaaaa actatttgag
     6541 tctttgggtt atacaagaga acatatagat tatgtagaaa gtttattgtc atatctagat
     6601 tctaaatgtc cacagattga gaatatttcc aggaaaaaag ttttaaaacc catgcatgag
     6661 attagaacta tcgagagtga gcaagatata caagatttta ttataaaagc ttttctttta
     6721 gtgaactgat aggtattttc ttagcaaacg ataaagtttt agggccgata caatcaattg
     6781 cctattcatt aaataagata aatacaacca aagatttaag gaaaccgttt ttaaaatact
     6841 taagtggaga gaagaatttt gtagacgctg aacatgataa taacggactg tatacttcat
     6901 caatagatga gatacacatg aaagatgttg tatattctat tacaccagaa aataaattaa
     6961 gtattgactt ctcatttaag tcaccattta gggtattatt aacaggaact tctggcagtg
     7021 ggaaaacaac gattttaaat ttaattaatg gttctttaaa gccacaaaaa ggttatgtaa
     7081 atttgttatc acatgggaaa aagagttcag attcaatacc aacagttgat cagacaccat
     7141 atatttttga cactactatt cgtgagaacg taactttatt tcaaaatgaa tatttttcag
     7201 atgatcagat aattgaggtg ttaaaaaagg taaatctata tgaagaatta gaaaagatag
     7261 atatactaaa ttataaatgt ggtgaaaatg gtagtaattt gtctggaggt caaaaacaaa
     7321 aaatagcttt agctagagct ctgattagaa ataataaagt gtacttattt gacgaaatat
     7381 cagctaattt agataatgat aattcaaatt ccatacatga tattctgttc aatttaggta
     7441 tttcatttat tgaagtttca catcattatg acttaaatga caagagatac actgatatat
     7501 ataaattgga aaatggaaca cttttcaaaa ttaagtgatt ggaggcaaga atatggataa
     7561 agattatata ttaaaagtga aagggctgta tcatcaattt ttactaggaa ataataaaac
     7621 gttgcaagtg ctgaaaaatg tttctctttc tgcttcgaga ggagaattta taagtattct
     7681 aggaattagt ggttctggaa agtcaacttt attaaaatgt atttctagtt tgcttgaacc
     7741 aacaagtggg gaagtaattt taaatggaat caacccctat aaaatcagaa atgcaaaatt
     7801 gtcaagtata agacgtaacg aagtatcttt tatatttcaa gcatacaatt taataccttc
     7861 cctgccggta atagaaaata tagcacttcc tttgcgatta tcacaaaaaa aattaactat
     7921 taaaaatgta gaaaacttac tcaaaagaat gaagtttaat gctggcttaa acgattttgt
     7981 tggaactctg tctggtggag aacaacagaa ggttgctata gctagagcgg ttattgctga
     8041 tagtgatata atatttgctg atgagccaac tggggcttta gacagcgttt ctcgtgaagt
     8101 aatttttgaa ttattgagag agttagtagg ggcgggtaag tgtgtaatta tggtaacgca
     8161 cgatatagaa ttggcctcga aaactgatcg tgcattaata ttgaaagatg gaaaaatttt
     8221 caaagaactt catagaccta gcggggaaga gttgtataaa atcttagagg tacaatcaac
     8281 tacggaggaa tagagatgct cagattagtt tactatcaat ttttacataa taagaaacaa
     8341 tggttaggcg tttcaccagt aatttttgtt tcgagtttag ttatgggatt ggctgttaat
     8401 ggggtaatta atgttgagaa taattcgcaa gtatttgtcg gacttccaga tcctaaacca
     8461 atttttatgt ttccgatagt attcggagga gtaacattat tctttgtgct ctctaacata
     8521 ataaatatgt tggttgaaat ttttagagat gattacgaac ttctggaggt gttgggagca
     8581 agtcgccttc aactatcatt tcttgtgggg ggacagattt ttatcatttc ctcgattatt
     8641 agttttattg catatctatg ctctatattt gttacgtcaa attattatta ttttttacaa
     8701 tactttttcg gggaaaatat attacctgat atccaatttc aaacgagtgc tgttggatgt
     8761 atcattacag tagtgttgat ttcattttta gcctttctaa gtggttgctt ttatacgttc
     8821 aagaagatta gaaataggaa gagttctaaa ataaggcatg ttctttcaat agtaaaaaga
     8881 atactgctat tggctggttt tagtgttatc tggttgcttt ctttgcaaca aattttccaa
     8941 gatagcacaa ttttagcgaa ggcccagata atattcaata ttgtaatctt agatattgtg
     9001 attatttatc aattatctcc ttttatacag tcatgtttta tcaaactact ttctataatt
     9061 atatttagaa ataattttat gttcattgtt tcgaagtgga atttactata ttgtaagtct
     9121 tatataaaat ctatcagtgc tgcaattaca ggagctatat tactaatttc tagttttcaa
     9181 atgatttctc agaatatact atctcaattt caagatgaca gtgatttaga gctaaaagta
     9241 gcatttattg tctatgtagg agcaccaatt ttgatagtac ttgcaaatat tatttcaatt
     9301 gcatttttgt catcgcatca agaaaggatt gagattcagc aatttgaaat tttaggaact
     9361 tctaattacc agatggttaa gattaaagtt ggtgaggcta tatttttgac atttgttact
     9421 tcattaattg catttttact taacattaaa attatggctt taatatacta ctctttagag
     9481 gatattttaa tagatgatat gaatcttttg gggttaatac ttccaaattt tatagtatct
     9541 attattttat ttattttaat atttattact aaaagttcct attttatctt taagaatgca
     9601 aaaattattt cttaaaaatt tgtaagtttt cgctatataa aatagttaaa tctattttgt
     9661 atcattgctt gcattttact ggtggagaga gtatatgagg gtggataaag tacttaatcc
     9721 caaaaattta aataggagga gctagctatg gcagcagaag tattaaatct tcaattagta
     9781 tctgttcaag ttgacgaaac agatgaagtt gatggaatgc gatttagtac attcagtaca
     9841 aaccgttgcg gtaactggag tgcttttagt tgggaaaatt gttaattcat ttaaattgta
     9901 aactttagag attctctgga gttatggatg tcgttccaat atgtgcacgt tggaatgtta
     9961 gtgcttatat gggggaacag aatcctctct tgattgaaga caagctagtc attaggctgg
    10021 tttgtctttt tgtcaactgt agtgggttga tataatagta ttagtgagtg ggataaaagt
    10081 ttcatttagt ttattcagta caaatttaac gggtcaagat ttaactaaag gagaagtaat
    10141 atggctgaac gattttggga gaacttgtcc attattttgg ctgaaagaaa tatcagctgg
    10201 attgagttaa ccagaaaaat gtttgcggga gagtttcact atccaagtga attgaatcgt
    10261 ttatatcaaa agattcgcca ctacaagatg gaacaacgaa tgcctcaaag tccatgggta
    10321 gaaaggattg tgcagatatt agatttagat tatgaagatt tatttcggag gtaactatga
    10381 aaagaataat tccagtttat atattccaac aagtaaatgt cctattggta tctctatact
    10441 tattgaaatt tctttgtatc ggtgagttaa ctatactaca ggttctctat ggtgcgtctc
    10501 ttttttcttt tttatggatg tatggtcaac gaaaacaagt ggtcaaggtc aatatgaaaa
    10561 ctaggatgaa atgccttggt attggactag ctagtctact gattataagt ctatgtttta
    10621 gcctgattca tgctcaagga agcacgaatc aaacaaattt aattggcctt caacatcaag
    10681 ttccttggtt ttcattttta ttgttcttaa tcaatgcgag tatggttgaa gaatttctgt
    10741 atcgtgaaat tttatggaac ttggttagaa aattagatat tcgagttgct ttgacaagtg
    10801 ttttatttgc cttagtacat catccaggaa ccattctagc ttggtgtctg tacgtttcac
    10861 ttggaatgtt tttaggtatg gtgcgctata aatctgactt atggggaagt atggggttac
    10921 atttggtgtg gaacttttta gtttatagtt tgctgctttt ttaaaatagg tgacctgatt
    10981 tatctcataa atctgtagtt ttt
//
LOCUS       DAVAGB010000058        10731 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVAGB010000058 DAVAGB010000000
VERSION     DAVAGB010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10731
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.059"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            68..565
                     /locus_tag="VQO19_001856"
     CDS             68..565
                     /locus_tag="VQO19_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HET1350074.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTAWDFTM
                     FEEKS"
     gene            565..2220
                     /gene="dnaX"
                     /locus_tag="VQO19_001857"
     CDS             565..2220
                     /gene="dnaX"
                     /locus_tag="VQO19_001857"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HET1350075.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVCLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2248..2442
                     /locus_tag="VQO19_001858"
     CDS             2248..2442
                     /locus_tag="VQO19_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HET1350076.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2592..3362
                     /gene="sufC"
                     /locus_tag="VQO19_001859"
     CDS             2592..3362
                     /gene="sufC"
                     /locus_tag="VQO19_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HET1350077.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3390..4652
                     /gene="sufD"
                     /locus_tag="VQO19_001860"
     CDS             3390..4652
                     /gene="sufD"
                     /locus_tag="VQO19_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HET1350078.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4663..5889
                     /locus_tag="VQO19_001861"
     CDS             4663..5889
                     /locus_tag="VQO19_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET1350079.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDRVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5876..6316
                     /locus_tag="VQO19_001862"
     CDS             5876..6316
                     /locus_tag="VQO19_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HET1350080.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQTSLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6370..7782
                     /gene="sufB"
                     /locus_tag="VQO19_001863"
     CDS             6370..7782
                     /gene="sufB"
                     /locus_tag="VQO19_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HET1350081.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8013..9254)
                     /locus_tag="VQO19_001864"
     CDS             complement(8013..9254)
                     /locus_tag="VQO19_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HET1350082.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIEQI
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9357..10466
                     /locus_tag="VQO19_001865"
     CDS             9357..10466
                     /locus_tag="VQO19_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET1350083.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFFYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSHLYENHKIMKERERELAK"
BASE COUNT         3183 a         1955 c         2335 g         3258 t
ORIGIN      
        1 aaatcctttg tttactaaac aagggatttt tcttttgtct ctgctccttt tttgatataa
       61 tagttctatg ttaaaatcag aaaaacaatc acgttatcaa atgttaaatg aagaattgtc
      121 cttcctattg gaaggcgaaa ccaatgtttt ggctaatctt tccaacgcca gtgctctcat
      181 aaaatcacgt tttcctaata ccgtatttgc aggcttttat ttgttcgatg gaaaggaatt
      241 ggttttaggc cccttccaag gaggtgtttc ctgcatccgt attgcactag gcaagggtgt
      301 ttgtggtgag gcagctcact ttcaggaaac tgttattgtt ggagatgtga cgacctatct
      361 caactatatt tcttgtgata gtctagctaa aagtgaaatt gtggtgccga tgatgaagaa
      421 tggtcagtta cttggagttc tggatctgga ttcttcagag attgaggatt acgatgctat
      481 ggatcgagat tatttggaac aatttgtcgc tattttgctt gaaaagacag catgggactt
      541 tacgatgttt gaggaaaaat cttaatgtat caagcacttt atcgaaaata tagaagtcaa
      601 aacttctccc agttagttgg tcaagaagtt gtggctaaga ctcttaaaca agcggtggag
      661 caagagaaaa taagtcacgc ttatcttttt tctggtcctc gtggaacggg aaaaaccagt
      721 gttgctaaaa tctttgccaa ggctatgaac tgtcccaatc aagtgggtgg cgaaccttgc
      781 aataactgct atatttgtca agcagtgacg gacggtagtt tagaagatgt cattgaaatg
      841 gatgcagctt ctaataatgg ggtagatgaa attcgcgaaa ttcgtgataa atctacctat
      901 gcgcctagcc ttgctcgtta taaggtttat atcatagatg aggttcacat gctgtctaca
      961 ggggctttta atgccctcct aaagacgctg gaagaaccaa cacagaatgt agtctttatt
     1021 ttggccacta ctgaattgca caagattcct gctactattc tatcccgtgt gcaacgtttt
     1081 gagtttaaat caattaagac acaggatatt aaggaacata ttcactatat cttagaaaaa
     1141 gaaaatatca gttctgaacc agaggctgtg gaaatcattg ccagacgggc ggaaggtgga
     1201 atgcgggacg ccttgtctat tttggatcaa gccctgagtt tgacacaggg aaatgagctg
     1261 acgactgcta tctctgaaga aattactggc accattagcc tatcagcctt ggatgattat
     1321 gtggcggcct tgtctcaaca ggatgttccc aaagctttgt cttgcttgaa tcttcttttt
     1381 gacaatggta agagcatgac tcgttttgtg accgatcttt tgcactattt aagagacttg
     1441 ttaattgttc aaacaggggg agaaaatact catcatagtt cagtctttgt agaaaatttg
     1501 gcacttcctc aaaaaaatct gtttgaaatg attcgcttag caacagtgaa tttagcagat
     1561 attaagtcta gtttgcagcc caagatttat gctgaaatga tgaccgtctg tttggcggaa
     1621 atcaagcccg aaccagctct atcaggagcg gttgaaaatg aaattgctac gctgagacag
     1681 gaagttgccc gtctcaaaca agagctttct aatgcaggtg cggttcctaa acaagttgca
     1741 ccagctccta gtcgaccagc tacgggcaaa acagtctatc gtgtcgatcg caataaagtg
     1801 caatctatct tacaagaggc cgtcgaaaat cctgatttag cacgtcaaaa tctaattcgt
     1861 ttgcagaatg cctggggaga ggtaattgaa agtctaggtg ggccggacaa ggctctgcta
     1921 gttggttctc aaccggttgc tgccaatgaa caccatgcta ttcttgcttt tgagtctaac
     1981 ttcaatgctg gtcaaactat gaaacgagac aatctcaata ccatgtttgg taatatcctc
     2041 agtcaggcgg caggtttttc acctgagatt ttagctattt ccatggagga atggaaagaa
     2101 gttcgcgcag ccttttcagc caaagccaaa tcttctcaaa ctgaaaaaga agtagaagaa
     2161 agcctgattc cagaaggatt tgaatttttg gctgataaag tgaaggtaga ggaagactaa
     2221 agaaagattt catgatacaa taagtttatg aataaacaac aatttattat tatggcgcta
     2281 tttacagctg ctgagaccta ttttttcaat gaagcctgga tgactggccg ctatattatg
     2341 gcagcctttt gggcaatttt actctttaga aatttccgag tcagttatgt gatgggtaaa
     2401 attgttgatg tcatcgatca gcattttaat aggaaagact agccctcagc ttccagacaa
     2461 aatcaaagcc ttttaggctt ttttttgtta tactagaaaa gtatatttat agaatttttg
     2521 ctctatttct ggggaaatca gacgtttttc tagtaagtac tgtaaaagtt ttgaaaaaga
     2581 aaggaactat catgtcagta atagagatca aagatcttca cgttgagatt gaaggaaaag
     2641 aaattttaaa aggggttaac ctgaccctga aaacaggaga aattgccgct atcatgggac
     2701 caaatggtac aggtaaatcg actctttctg ccgctatcat gggaaatcca aactatgaag
     2761 taactaaagg tgaagttttg tttgatggcg taaacatcct tgagttggaa gtggatgagc
     2821 gtgcgcgtat gggacttttc cttgctatgc aatacccatc agaaatccct ggaattacca
     2881 atgctgagtt tcttcgtgcc gctatgaatg cgggtaaaga agatgatgag aagatttcag
     2941 ttcgtgagtt tattactaag ctagatgaaa aaatggaatt gctcaacatg aaagaagaaa
     3001 tggcagagcg ttacctcaac gaaggcttct ctggtggtga gaaaaaacgc aatgaaattc
     3061 ttcaactttt gatgttggag ccaacatttg ctcttttgga cgagattgac tcaggtcttg
     3121 atattgacgc tcttaaagtt gtgtctaaag gtgtcaatgc catgcgtggt gaaggttttg
     3181 gtgctatgat catcactcac taccaacgtc ttttgaacta tatcacacct gatgtggtac
     3241 acgtgatgat ggaaggtcgt gttgtccttt ctggtggtcc agaattggct gcgcgtttgg
     3301 aacgtgaagg atacgcaaaa ctagctgaag aacttggcta cgactacaag gaagaattgt
     3361 aattccctcg tatcttttag gagaagtaaa tgactagaga aaatattaaa cttttttcag
     3421 aaatgcacgc tgaaccaagc tggttggctg atctccgtca aaaagctttt gacaagattg
     3481 agactttgga attaccagtt attgagcgtg tcaaattcca ccgttggaat ctgggtgatg
     3541 gaacgattac agaaaatgag ccatcagcaa atgttccaga tttcacagct ttagatcatc
     3601 acttgaagtt ggtgcaagta ggaactcaaa ctgttttcga acaaactcca gttgagttag
     3661 ctgaacaggg tgttgtcttc acagactttc actcagcttt agaagaaatt ccagagctga
     3721 tcgaagaatt cttcatgtca tctgttaagt atgatgatga caagttggcg gcttaccaca
     3781 cagcttattt taacagtggt gctgtactct atattccaga taacgtagaa atcacagagc
     3841 caattgaagg aattttctac caagatagcg atagcaatgt gccgtttaac aagcatatta
     3901 tgattatcgc tggtaaaaat tctaagatta gttatctgga gcgtttagag tcacgcggtg
     3961 aaggaagtga caaagtaact gccaatatca cagtggaagt gattgcacgt tctggtgcgc
     4021 aagtcaagtt tgctgctatc gaccgtctag gtgaaaacgt cactgcctac attagccgtc
     4081 gtggtaaatt aggcaacgat gcaagtattg actgggctat cggtgtcatg aacgaaggaa
     4141 atgtcgttgc tgattttgat agtgacttga ttggtaatgg tagccatgct gacctcaagg
     4201 ttgtagctct ttcaagtggt cgtcaggtac aagggattga tactcgtgta actaactatg
     4261 gctgcaactc tatcggaaat atcctacaac atggggttat ccttgaaaaa gcaactttga
     4321 ctttcaatgg tatcggccac atcatcaagg gtgctaaggg agcagatgcg caacaagaga
     4381 gccgtgttct catgctttca gaccaagcgc gttcagatgc taacccaatt cttttgattg
     4441 atgaaaatga tgtcactgca ggacacgcag cgtctatcgg acaagttgat ccagaagaca
     4501 tgtattacct catgagtcgt ggattggata aggcaactgc agagcgtttg gttgttcgtg
     4561 gtttccttgg atctgttatc gtggagattc cagtcaagga agttcgtgat gaaatgattg
     4621 caactatcga agagaaattg tcaaaacgct aaggggaagc ctatgttaga tgtagaagcg
     4681 attcgcaagg attttccaat tttagatcag attgtcaatg atgaacctct ggtctatctg
     4741 gacaatgctg cgacgacaca aaaaccacta gtagttctga aagctattaa cagttactat
     4801 gagcaggaca atgccaatgt tcaccgtggt gtccatacct tagcggaacg agcgacagct
     4861 tcttatgaag ctgctcgtga aaccattcgt aagtttatta atgcaggctc tacaaaggaa
     4921 gttctcttta ccagaggaac gacaaccagc cttaactggg tggcacgctt tgctgaggaa
     4981 attctcgctg agggagaccg ggtcttgatt tcagtaatgg aacaccattc taatatcatt
     5041 ccatggcagg aagcttgtcg aaagactgga gcagagcttg tctatgtcta tcttaaagac
     5101 ggtgccttgg atatggagga tttgcgagct aaattgactg ataaggttaa atttgtttcc
     5161 ctagctcatg cctccaatgt tcttggtgtg gtcaatccga tcaaggaaat cactcaatta
     5221 gcccaccaag ttggggcaat tatggtagtg gatggtgctc aatctacacc tcatatgaag
     5281 attgatgtcc aggacttgga tctggacttt ttcgcctttt cgggtcacaa gatggctggt
     5341 ccgactggta tcggtgtcct ttacggcaaa gaaaagtatc ttgagcaaat gtctccagta
     5401 gaatttggcg gcgagatgat tgattttgtc tacgagcaat ttgctagttg gaaggaattg
     5461 ccttggaaat ttgaggctgg aacgccaaat atggcaggag ctattggact tgcgactgca
     5521 gttgattatc tggaaaagat tggtatggat gccgttgaag ctcatgaaca ggaattgatt
     5581 gcgtacgtct atccaaaact gcaggcaatt gagggattga ccatttacgg ttctcaggat
     5641 ttggctcaac gttcgggtgt tattgccttt aacctaggtg atctccatcc tcacgatctt
     5701 gcgacggctc tggattatga aggagtggct gttcgtgctg gtcaccattg tgcgcaaccc
     5761 ttgcttcagt atttggaagt cccagcaaca gctcgtgcaa gtttttatat ctacaatacc
     5821 aaggcagatt gcgacaaact agtcgatgcc ctacaaaaga caaaggagtt tttcaatggc
     5881 actttctaaa ctagatagcc tttatatggc agtggtagca gaccattcga aaaatccaca
     5941 tcaccaaggg aagttagaag atgctgagca aaccagtctc aacaatccga cttgtgggga
     6001 tgtcatcaac ctctctgtca agtttgatgc agaggaccgt ttggaagata ttgcttttct
     6061 aaattcagga tgcacgattt caactgcttc tgctagtatg atgacagatg ccgttttagg
     6121 aaaaaccaaa caagaaattt tagaactggc gactattttt tctgaaatgg ttcaagggca
     6181 aaaagatgag cgtcaaggcc aacttggaga cgcggcattc ttgtcaggtg ttgccaaatt
     6241 ccctcaaaga atcaagtgtg caaccctagc ttggaatgcc cttaagaaaa caattgaaaa
     6301 tcaagaaaaa cagtaagaca agtttctttt gtcttatgaa ttattagaaa tgaagaaaga
     6361 aaggatacta tggctgaaga aagagtagaa ccaaaaccaa ttgaccttgg tgaatataaa
     6421 tttggtttcc atgacgatgt agagcctgtc ttatcgacag gaaaaggact caacgaaggt
     6481 gttattcgtg aattatctgc tgctaagggt gagcctgagt ggatgttgga gttccgtttg
     6541 aagtcttatg aaaccttcaa aaaaatgccc atgcaaactt ggggagcaga cttgtcagag
     6601 attgactttg atgacttaat ctactaccaa aaaccatctg acaaaccagc ccgttcttgg
     6661 gatgatgtac ctgaaaagat taaagaaacc tttgaacgta tcgggattcc agaagctgaa
     6721 cgtgcttatt tagcaggggc ttctgcccag tacgagtcag aagtggttta ccacaacatg
     6781 aaggaagagt tccaaaaatt aggtattatc tttacagata cagattccgc actcaaggaa
     6841 tacccagact tatttaaaca atactttgcg aagttggtac cgccgacaga taacaagttg
     6901 gcagccctca actcagcagt atggtcgggt ggaactttta tctacgtgcc aaaaggtgtc
     6961 aaggtagata ttccacttca aacttatttc cgtatcaata acgaaaatat aggtcagttc
     7021 gaacgtacct tgattatcgt tgatgaggga gcaagcgtcc actacgtaga aggatgtaca
     7081 gcaccaacat attcaagcaa tagcttacac gctgccattg tagaaatttt tgctttggac
     7141 ggagcttata tgcgttatac aactatccaa aactggtctg ataacgtcta taacttggta
     7201 acaaagcgtg ctaaggctca aaaggatgct actgttgagt ggattgatgg aaacttgggt
     7261 gccaaaacga ctatgaaata tccatctgtt taccttgatg gagaaggagc gcgtggtacc
     7321 atgctctcta tcgcctttgc taatgcaggg caacaccaag acacgggtgc taagatgatt
     7381 cacaatgctc cacataccag ctcgtctatt gtgtctaaat ccatcgctaa aggtggagga
     7441 aaggttgact accgtggaca agtcaccttt aacaagaact ctaagaaatc tgtttcccac
     7501 attgaatgtg ataccattat catggatgac ttgtcagcat cagatactat tccatttaat
     7561 gaaattcaca actcgcaagt ggctttggaa cacgaagcca aagtatctaa gatttcagaa
     7621 gagcaattgt attatctcat gagccgtgga ttgtcagaat ctgaggcaac tgaaatgatt
     7681 gtcatgggat ttgtagaacc ctttacaaaa gaacttccaa tggaatacgc agttgagctg
     7741 aaccgcttga ttagctatga aatggaggga tcagttggat aaaatttgat tttatactct
     7801 tcgaaaatct cttcaagcca cgtcagcatc gccttaccgt atgtatggtt actgacttcg
     7861 tcagtttcat ctacaacctc aaaacagtgt tttgagcaac ctgcggctag cttcctagtt
     7921 tgttctttga ttttgagtat tagatttact caaaatcaag gattttgaag atgaacttgt
     7981 atcaaaaaat cgcggtttaa aatcgcgatt ttttataatt tctcgttaac aaagcggaca
     8041 aactgattcc accaaacttt taagaagaag gctttttcaa ttttcttgtc tgctaccatt
     8101 tcgaaactag ggcgctctgt ggtgatgtaa ccttgaccaa tcaagtcctt gtcttcataa
     8161 gtcaaatggc caaccactgt tccagcttca agtggtgctg ggattgcttt ggaatcaggt
     8221 gtgaattgaa cagattggga agattgattc ccaatctgtt cgattagata gatatcctct
     8281 ggagccactg cagttactgt atcttctttt ccatcttgta caggggcttt gctatcttga
     8341 taggcatcgc cttgttgaac gattttgcga agtgtaaatg tagaagaaat ataatccatt
     8401 agggaagatg tagctgtaaa tcgagcgtaa ggattattgt cttgatgatc tgcatttaaa
     8461 acaactgtga tgactctcat gcctttttcg acagtagtac caacaaaaga ctctccagcc
     8521 ttatctgttg ttcctgtttt tagcccatca aaaccaccac ggtaagcagg cataccttct
     8581 aacatgtagt tggttgaagt gattgtcatc ccagcaaaag tagaagaagg ttttttagtg
     8641 atttctaaga cttgtgggta ttttttgatg aggttgcgag caacgatagc gacatcataa
     8701 gcactaagct tattttcctc atctttttta gaacctgggt aaatgttatc ccctagagtt
     8761 tcattgttaa gacctgtcgt attgacaaca gtggcatcct gaattcccca ttccaagagt
     8821 tttgcccgca tcatatcgac gaaatctttt tctgagccag caattttctc agctagggca
     8881 atagcggcgc tgttggcact agataccaga gttgcttcaa gcaactcttc gacagtataa
     8941 ttacgggcct ccataggaat attactggct tcagaatttg tcgtcaattg ataaggataa
     9001 tcagaaatat ctacaggagt ggagagggta atacttccgt tttccaaagc ttcatagacc
     9061 agataaacag taatcaattt tgttatggaa gcaatttcga caggttgcgt tgcatccttc
     9121 tcatagagaa ttttaccagt atttgcctca acagcaatcg catgtttagc ggcaatggta
     9181 aaatcttgag caacagcagt agaagcaccc cctaaaagag agacagttaa caaagttaaa
     9241 aatatttttt tcatagtagt cttattctat cataaagaaa aaaaatattc ttgctttaat
     9301 aattcatctg ttaagctttt tgaaaatatg gtaaaataaa gtaagggagg taactcatgt
     9361 ttcgtagaaa taaattattt ttttggacca cagaaatttt actcttaacc atcatctttt
     9421 acctatggag acagatgggg tctttgatta acccttttgt tagcgtgctt aatacaatta
     9481 tgattccatt tttattaggg ggcttttttt attatttgac aaaccctatt gttactttct
     9541 taaataaagt ctgtaaactc aatcgtttgc ttggtatttt aattaccttg tgtactttgg
     9601 tctggggaat ggtcataggt gttgtctatc tcttacctat tttgattaat cagttatcta
     9661 gtttgattat atctagtcaa actatttata gtcgagtaca agacttaatc atagacttat
     9721 ctaattatcc tgcgctccag aatttggatg tagaagctac aattcagcag ttaaacttat
     9781 cctatgttga tattcttcaa aatatcctaa atagcgtatc aaatagtgtg gggagcgtct
     9841 tgtcagctct tatcagtact gttttgattt tgattatgac tccagttttt ttggtttatt
     9901 tcttattaga tggacataaa ttcttgccca tgcttgaaag aacgattcta aagagggatc
     9961 gcttgcatat tgcaggctta ttaaagaatt taaatgcgac gattgctcgc tatattagtg
    10021 gagtttcgat tgacgcaatc attataggtt gtttggctta tattggctat agtattattg
    10081 gtttaaaata tgctttagtt tttgccattt tttctggtgt agccaattta attccttatg
    10141 tggggccaag tattggtttg attcctatga tcatcgcaaa tatattcact gatccccata
    10201 gactgctgat tgcagtgatt tatatgcttg ttgttcagca ggtagatggc aatatcttat
    10261 atcctcgaat cgtaggaagt gttatgaagg ttcatccaat cacgatttta gttttacttt
    10321 tgttgtcaag caatatctat ggtgtagttg gaatgattgt cgcagtgcca acctattcta
    10381 tcttgaaaga aatttctaag ttcttatccc atttgtatga aaatcataaa ataatgaaag
    10441 aacgagaaag agaattagct aagtaaaagt caggagaacc ctgatttttc tttactggaa
    10501 gtggccttta gattagaaga ctgaaaataa gttaaagtct taaactaatt ttcacagcta
    10561 agaatagtag aagttaatct gataaaaatc gaaaaaacca gtggaattct gtgtcagggt
    10621 aagttccact ggttttcata gtctattaaa gttcgaatga aacctattta tagtagattg
    10681 aaactagaat agtacacctc taattctaaa acattgttag aaatcgattt g
//
LOCUS       DAVAGB010000059        10330 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVAGB010000059 DAVAGB010000000
VERSION     DAVAGB010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10330
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.060"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            89..1264
                     /gene="mutY"
                     /locus_tag="VQO19_001866"
     CDS             89..1264
                     /gene="mutY"
                     /locus_tag="VQO19_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HET1350084.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDCDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            1319..2023
                     /locus_tag="VQO19_001867"
     CDS             1319..2023
                     /locus_tag="VQO19_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET1350085.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2016..3365
                     /gene="vicK"
                     /locus_tag="VQO19_001868"
     CDS             2016..3365
                     /gene="vicK"
                     /locus_tag="VQO19_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HET1350086.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3367..4176
                     /locus_tag="VQO19_001869"
     CDS             3367..4176
                     /locus_tag="VQO19_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET1350087.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4267..4509
                     /locus_tag="VQO19_001870"
     CDS             4267..4509
                     /locus_tag="VQO19_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HET1350088.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4511..4765
                     /locus_tag="VQO19_001871"
     CDS             4511..4765
                     /locus_tag="VQO19_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET1350089.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4812..5588
                     /locus_tag="VQO19_001872"
     CDS             4812..5588
                     /locus_tag="VQO19_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HET1350090.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMTDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLTILPLNAIFTVFRLGRIFRLARLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPVSLFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSSQRILIEKQSEKIEELHRMIKDLVEKIS"
     gene            complement(5844..6830)
                     /locus_tag="VQO19_001873"
     CDS             complement(5844..6830)
                     /locus_tag="VQO19_001873"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HET1350091.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            7024..9492
                     /gene="gyrA"
                     /locus_tag="VQO19_001874"
     CDS             7024..9492
                     /gene="gyrA"
                     /locus_tag="VQO19_001874"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HET1350092.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            9492..10235
                     /gene="srtA"
                     /locus_tag="VQO19_001875"
     CDS             9492..10235
                     /gene="srtA"
                     /locus_tag="VQO19_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HET1350093.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSNEILTAFNQPYKQFY"
BASE COUNT         3210 a         1756 c         2299 g         3065 t
ORIGIN      
        1 agtagataga aaagttatat actatctatt gaaaatatta taaatcagat acaaagacag
       61 gtgaaacctt ctgtgttata ctagagatat gttagatttg aaagaatacg gtatcgtcat
      121 gtggccggag gagaaagtca tttctttccg tgagaaactt ctcgcttggt atgatgaaaa
      181 caaaagagat ttgccttgga ggagaagtaa aaatccttat cacatctggg tatctgaaat
      241 catgcttcag cagaccaggg tggatacagt tatcccttac tacgaaagat ttttggactg
      301 gtttccaact gtcgaaagtc tggcaactgc gcctgaggag agtttactga aagcttggga
      361 gggcttgggc tattattctc gagttcgcaa tatgcaggct gcagcccagc agattatgac
      421 tgactttggt ggccaatttc caaataccta tgaaggaatt tccagcttga aagggattgg
      481 accttacaca gcaggagcca tttccagtat tgcttttaac ttgcctgagc cagctgtaga
      541 tggtaatgtc atgcgggtct tggcgcgtct gtttgaagtc aaccacgata ttgggattcc
      601 aagtaatcga aaaatttttc aggcaatgat ggagatcttg attaatccag atcgtccggg
      661 tgattttaat caagccttga tggacttagg gtctgatatt gagtctcctg taaatcccag
      721 acctgaagaa agcccagtca aggactttag tgcggcatat cagaatggaa ccatggaccg
      781 ttatccaatt aaatctccta agaaaaagcc ggttcctatt tatcttaaag ccttagttgt
      841 gaaaaattct caaggacaat ttttacttga aaaaaatgaa agcgaaaagc tcttggcagg
      901 tttttggcat ttccccttta tagaagttga taacttttcg caagaagagc agtttgacct
      961 ctttcatcag gttgcggaag aaagtgtgaa ctttggcccc agtccagaag agagtttcca
     1021 gcaggactgt gacctagatg ttgattggct tgatgtttgt tttgatacag tccagcatgt
     1081 ttttagtcat cgaaaatggc atgtacagat tgtagcaggt caggtgagtg acttccatga
     1141 tttttcagat agggaagttc gttggctttc accagaagaa ttcaagaatt acccacttgc
     1201 caaaccccaa caaaaaatct ggcaggctta tgcacaagcc aacttagaca gtagccaaga
     1261 ctagctattg tgtcttctga ctattttttg gtataatagt agagaaaaag gtgaacatat
     1321 gaaaaaaata ctaattgtag atgatgagaa accaatctcg gatattatca agtttaatat
     1381 gaccaaggaa ggttacgaag ttgtaactgc ttttaatggt cgtgaagcgc tagagcaatt
     1441 tgaagcagag caaccagata ttattattct ggatttgatg cttccagaaa ttgatggttt
     1501 agaagttgct aagaccattc gtaagacaag cagtgtgccc attcttatgc tttcagccaa
     1561 agatagtgaa tttgataagg ttatcggttt ggaacttggg gcagatgact atgtaacgaa
     1621 acccttctcc aatcgtgagt tgcaggcgcg tgttaaagct cttctgcgtc gttctcaacc
     1681 tatgccagta gatggtcagg aagcagatag taaacctcaa cctatccaaa ttggggattt
     1741 agaaattgtt ccagacgcct acgtggctaa aaaatatggc gaagaactag acttaaccca
     1801 tcgtgaattt gagcttttgt atcatttagc atcgcataca ggtcaagtca tcacgcgcga
     1861 acacttgctt gagactgtct ggggttatga ctattttggt gatgtccgca cagttgatgt
     1921 gactgtacga cgtctgcgtg agaagattga agatacgccc agccgaccag agtatatctt
     1981 gacgcgccgt ggtgtagggt attacatgag aaataatgct tgatttactg aaacaaacca
     2041 tttttaccag agattttatc tttatcctga ttttgttagg tttcatcctt gttgtgaccc
     2101 tcttattact ggaaaataga cgtgataata ttcagttgaa gcaaatcaat caaaaggtta
     2161 aagatttgat tgcaggagat tattccaagg ttcttgatat gcaaggtggg tctgaaatca
     2221 ccaatattac caataatttg aatgacttgt cggaggttat tcgtctcact caggaaaatc
     2281 tagaacaaga gagtaagagg ctaaatagta ttctgtttta tatgacagat ggggttcttg
     2341 cgaccaaccg tcggggtcag attatcatga ttaacgatac agccaagaag caactggggt
     2401 tggttaagga agatgttctg aatagaagca ttttggaatt gctcaagata gaagaaaact
     2461 atgaattgcg tgatttgatt acccaaagtc cagaattgtt gctagattcc caagatatca
     2521 atggcgaata tttgaacctt cgagttcgct ttgccttgat acgtcgagag tctggcttta
     2581 tttcaggttt ggtggctgtt ttgcatgata cgacggagca ggagaaggaa gaacgcgaac
     2641 gaagactctt tgtttccaat gttagccatg agttacggac tcctctgact agcgtaaaat
     2701 cctatcttga agccttggat gagggggctt tgtgtgaaac tgtagcacca gactttatca
     2761 aggtttctct tgatgaaacc aaccgtatga tgcgcatggt gacggatctc ctccatcttt
     2821 cacgtattga taatgctacc agtcatctag atgtggaact gattaacttc actgctttta
     2881 ttacctttat cctcaatcgt tttgacaaga tgaaaggaca ggaaaaggaa aaaaaatatg
     2941 agttggtgag agattatccc atcaattcta tctggatgga aattgataca gataagatga
     3001 cgcaggttgt cgacaatatt ttaaataatg ctattaagta ttcgccagat gggggtaaaa
     3061 tcactgtcag aatgaagaca actgaagacc agatgatttt atccatttct gaccacggtt
     3121 tggggattcc taagcaggat ttaccacgta tctttgaccg tttctatcgt gtggatcgtg
     3181 ctagaagtcg tgcacaaggt ggtacaggtc taggactgtc tatcgctaaa gaaattatca
     3241 aacaacataa gggctttatt tgggccaaga gtgaatacgg caagggttca acctttacca
     3301 ttgtgctccc ttatgataag gatgcagtga aagaagaagt atgggaggat gaagtagaag
     3361 actagaatga gtgaaatagg ctttaaatac agtattttag cgtcgggttc cagtggaaat
     3421 tctttttatc tggaaacctc aaaaaagaag cttttagtag atgcaggctt gtctggcaag
     3481 aaaattacca gtctgctagc tgaaattaac cgtaagccag aagacctgga tgccatcttg
     3541 attacccatg agcattcaga tcatatccat ggagtaggcg ttttggctcg caagtatggt
     3601 atggatcttt atgccaatga aaagacctgg caagctatgg aaaatagtaa atatcttggc
     3661 aaggtggatt cttcgcaaaa gcatattttt gaaatgggta aaaccaaaac ctttggagat
     3721 atcgacatcg agagttttgg tgtaagccat gatgcagtcg caccgcagtt ctatcgcttt
     3781 atgaaggatg ataagagttt tgtccttttg acagatacag gttatgtcag tgaccgtatg
     3841 gcgggcattg tcgaaaatgc ggatggttat cttatcgagg ccaaccatga tgtagagatt
     3901 ttgcgatcag gttcttacgc ttggcgactc aaacaacgaa tcctatctga ccttggtcac
     3961 ctttctaacg aggacggtgc tgaagctatg attcggacgc taggaaatcg tactaagaag
     4021 atttaccttg ggcatttatc taaggaaaac aatatcaagg aactggctca tatgaccatg
     4081 gtcaatcagc tggctcaagc tgatctggga gtcggagtag actttaaggt ttatgatacc
     4141 tcaccagata ccgcaacacc attgacagag atatagaaag aacgctgaga aggtgttctt
     4201 tttatattga ctggacacct aaaaagtaat acaatggtgt taccattaaa aaagggagca
     4261 caaaagatga ctactattac attaaaagtt tctgaagctg ataaaacatt tatgaaagca
     4321 atggctaagt ttgaaggagt ttccctttcg gaacttattc gcaccaaaac tcttgaagcc
     4381 ctagaagatg aatacgatgc tcgtgtggca gatttagcct atcaagagta tttagaagac
     4441 ttggaaaaag gagttgaacc cattacttgg gaagaaatga tgcatgattt aggcttgaag
     4501 gatgaataat ttgtataaat tagttccaac aagacgtttt atcaagcaat tgaaaaaatt
     4561 ggaccgttat acgcagaagc taattacaaa ctatttacaa accaatgttt tggaagatcc
     4621 aagacgacac ggaaaggctt tggttggtaa tcgcgttggt caatggcgct atagaattgg
     4681 taattatcga gttatcgtac aaattgtaga tgatgaatta gttgttgcta ctctagaagt
     4741 tggtcatcgg agagatattt attgaattaa agctgagtaa taacaatata gaaagtaagg
     4801 agagtaaaaa tttgaagaaa aaatggtttt ttgcagatta ttatgataca acaattattt
     4861 tacttgcttt aatctctgtt attctggtat tacttggatt tgctgagatg actgatttgg
     4921 acaatccgcc ttatagtatt attgatttag taatctgggg tgtttttgta attgattata
     4981 gttggcgctt ttttattact aaaagaaaat ggcgctttat tcttgaaaat atttttgatt
     5041 tattgaccat tctcccttta aatgctattt ttacagtgtt tcgattagga cgtatcttcc
     5101 gcttagcaag gctgacaaaa ttactgaaac tgactcgttt acttagaata attggactta
     5161 caggtaaact agaaagaaaa attagtagat tcttacgaac aaatggattg atttatatct
     5221 tgtatgttaa tatctttatt gttctagtag ggagttcgat tttatccgtt gttgaagaaa
     5281 aatccttctc agatagtctt tggtgggctc ttgtgacagt aactactgtt ggttatggtg
     5341 atattgttcc agtttccctt tttgggaaat ggctagcagt tttactgatg cttgtcggta
     5401 ttggaacaat agggatgcta acaagtgctt tgacgaactt ttttgtaaag gataatccag
     5461 atgaacagat aaaacttgat aaactcaaag acgaattatc gagccaaaga atattaatag
     5521 agaaacaatc tgaaaaaatc gaagaactac atcgaatgat aaaagactta gttgaaaaaa
     5581 tatcataaag gtgagacaaa acaaaacttg attcgaggag aaatcaagta agttttgaca
     5641 caatagaacg catattatca ggtataaaaa cttgatacta tgcgttttat agagaaataa
     5701 aataaaatct gaacaaatca attaggaatt taaagcattt tataacaacg ttttagagtg
     5761 atagggtgct atttcaactt caacctacta taatacagaa aaaaacaact ccctgatgat
     5821 tcaaggagtt gtctatagtt aaattagttt ttagaagctt cttggaattc tggatttttc
     5881 catgcttcgt caataatagc ttgcaattct ttagcagatg cttgcatttt ttgagtttct
     5941 gcatcgttca atggaatatt tactggacga acgataccat gtgcaccaac aacagctggt
     6001 tgaccgataa agacattctc aactccgtat tgaccttctt ggaatactga aagtggaagt
     6061 actgcgtttt catcgtcaag gattgcttta gtgatacgag caagggctac tgcgataccg
     6121 tagtatgttg cacctttttt gttgatgatt gtgtaggctg catcacgaac accttcgaac
     6181 aattcaatca attcagcttc ttgaacattt tgagtgtctt taaggaattc ttcaagattt
     6241 acaccagcga tgttagcgtg tgaccaaaca gcgaactcag agtcaccgtg ttcacccatg
     6301 atgtaggcgt gcactgaacg agcatccaca tccaattttt cagcaagtgc ttgacggaaa
     6361 cgagctgagt caagtgaagt acctgaaccg ataacgcgtt ctttagggaa accagagaat
     6421 ttccaagttg agtaagtcaa aacgtcaact gggttagcag caacaaggaa gatacctttg
     6481 aaaccagatt caacaacttg agttacgatt gatttgttga tagcaaggtt tttacctaca
     6541 aggtcaagac gagtttcacc tggtttttga ggtgcacctg cagtgatcac aacaaggtca
     6601 gcgtctgcac agtcagagta ttgagctgca tagatttttt taggtgaagt gaaggcaagg
     6661 gcgtgactaa ggtcaagcgc atcaccaaca gctttttcat gcaattgtgg aatttcgata
     6721 attccaagct cttgtgcaat tccttggtta acaagtgcaa aagcgtaaga tgaacctaca
     6781 gcaccatcac cgacaaggat aacttttttg tgttgtttag ttgaagtcat tgttttaaac
     6841 atctccttaa ttttattagg ggattttccc tagacaactt cattctatca cttttaaaaa
     6901 actttgtcac gaatatgcct tatagttctc gatgtaaacg ttttagtggt ttagaggctg
     6961 aaatagatgg gaatttatgg tataatgttg ttacttacta attgtgaaat gaggcattta
     7021 ttaatgcagg ataaaaattt agtgaatgtc aatctgacaa aggagatgaa ggcaagtttt
     7081 atcgactacg ccatgagtgt tatcgtagcg cgagctcttc ctgatgttcg agatggctta
     7141 aaacctgttc accgtcgcat tctctacgga atgaatgaat tgggtgtgac cccagacaaa
     7201 ccccataaaa aatctgctcg tattacaggg gatgtcatgg gtaaatatca cccacacggg
     7261 gattcctcta tttatgaagc catggtccgt atggctcaat ggtggagcta ccgttacatg
     7321 cttgtagatg gtcatgggaa ttttggttcc atggatggag atagtgctgc cgctcaacgt
     7381 tataccgagg cacgtatgag caagattgct ctggaaatgc ttcgtgatat caacaaaaat
     7441 acagttgatt tcgttgataa ctatgatgcc aatgaacggg aacccttggt cttgccagcg
     7501 cgttttccaa accttttggt taatggagca actggtatcg cggttgggat ggcaaccaat
     7561 attccacctc ataatctggg tgaaaccatt gatgcagtga agttggtcat ggataatcct
     7621 gaagtgacta ccaaggactt gatggaagtc ttgcctggac cagattttcc aactggtgct
     7681 cttgtcatgg ggaaatcagg tatccataag gcttatgaaa caggtaaagg ttcgattgtc
     7741 ctacgttctc gtacagagat tgaaacgact aagactggtc gtgagcgtat cgttgtaaca
     7801 gaatttcctt acatggtcaa taaaaccaag gtgcatgagc atattgttcg cttggttcag
     7861 gaaaaacgca ttgagggtat cacagcagta cgtgatgagt caaaccgtga aggtgttcga
     7921 tttgttattg aagtcaagcg cgacgcctca gccaatgtta ttctcaataa cctcttcaaa
     7981 atgacccaaa tgcaaaccaa ttttggtttc aatatgctcg ctatccaaaa tggtataccg
     8041 aaaattttgt ctcttcgtca gattttggat gcttatatcg agcaccaaaa agaagtggtt
     8101 gttcgtcgta cacgttttga taaggaaaaa gcggaagcgc gcgctcatat cttagaaggt
     8161 ctcttgattg cgctagacca tatcgacgaa gtgattcgta tcatccgtgc tagtgaaacg
     8221 gatgcggaag ctcaagctga gttgatgagc aagtttaagc tttctgaacg tcaaagtcaa
     8281 gctatccttg atatgcgtct tcgtcgtttg acaggtttgg aacgcgataa gattcaatct
     8341 gagtatgatg acctcttggc tctgattgcg gatttagcag atattcttgc taagcctgaa
     8401 cgtgtttctc aaattatcaa agacgaattg gatgaagtta aacgtaaatt ttctgataag
     8461 cgccgtacag agttgatgat tggacaggtc ttgagtctcg aggatgagga cttgattgaa
     8521 gaatcggatg tcttgattac cctttctaac agaggctaca ttaagcgttt ggatcaggac
     8581 gagttcactg ctcaaaaacg tgggggtcgt ggtgtccaag gaacgggagt gaaagatgat
     8641 gactttgttc gtgagttagt gtcaactagc acccatgatc atctgctctt cttcacaaac
     8701 aagggacgtg tctatcgtct taaaggttat gaaattcctg agtatggtcg gactgccaaa
     8761 gggctaccag tagtcaatct cttgaaattg gatgaagacg aaagtattca gacggttatc
     8821 aatgttgagt ctgatcgcag tgatgatgct tatctcttct ttacaacccg tcacggtatt
     8881 gtgaagagaa ccagtgttaa ggagtttgcc aatattcgtc aaaatggtct caaagcgctg
     8941 aatttaaagg atgaagatga gttaatcaat gtcttgttgg cagaaggaga tatggatatt
     9001 atcattggta ccaagtttgg ttatgcagtt cgctttaatc aatcagccgt tcgtggtatg
     9061 agtcgtatcg ccactggtgt gaaaggtgtt aaccttcgtg aaggagacac agttgttggt
     9121 gccagcttga ttactgatca agatgaggtt cttattatca cagaaaaagg atatggtaag
     9181 cgtacagtcg ctactgaata cccaacaaaa ggtcgtggtg gtaagggaat gcagacagct
     9241 aaaattaccg aaaaaaatgg cttgctggcc ggtcttatga ctgttcaagg ggatgaggat
     9301 ttgatgatta tcactgatac aggtgtcatg attcgaacca atcttgccaa tatttcacaa
     9361 acaggacgtg caactatggg agttaaagta atgcgcctgg atcaagatgc tcagatagtg
     9421 actttcacaa cggttgcggt ggcagaaaaa gaagaagttg ggacagaaaa cgaaacagaa
     9481 ggtgaagcat aatgtctcaa aaaaataata aaaagaaaaa caagcgaaaa aatctgctga
     9541 caaatatcct agcaggattt ctgatattac tgtcactggc tttgattttt aatactcaaa
     9601 ttcgaaatat tttcatagtc tggaatacca ataagtatca agttagccag gtatcaaaag
     9661 aaaaattaga agaaaatcag gatacagaag gcaattttga ctttgattct gtcaaagcta
     9721 tctcttcgga agctgttcta acttctcaat gggatgctca aaaattacca gttattgggg
     9781 gaattgcaat tcctgaattg gaaatgaatt tgccgatttt taaaggactt gataatgtta
     9841 atctcttcta cggagctggt acaatgaaac gcgagcaagt aatgggagaa ggaaattata
     9901 gtctagctag tcaccatatc tttggtgttg ataatgctaa taaaatgtta ttttctcctt
     9961 tagataatgc taaaaatggc atgaagattt atctaaccga taaaaataaa gtttatactt
    10021 atgaaatacg tgaagtcaaa cgtgtgacac cggatcgtgt tgatgaagtt gatgatagag
    10081 atggggtcaa tgaaatcaca ttagtaacct gtgaagacct tgctgctaca gaacgtatta
    10141 ttgtcaaagg tgatttgaaa gaaacaaaag attattcaca aacatctaat gaaatcctaa
    10201 cagctttcaa tcaaccatat aaacaatttt attaatacaa atcagtgaaa tcatggattt
    10261 cactgatttt ttaagatttt cataaaaata tagtaaaatg aaataagaat aggacgaatc
    10321 gttcaggaca
//
LOCUS       DAVAGB010000060         9955 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVAGB010000060 DAVAGB010000000
VERSION     DAVAGB010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9955
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.061"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(39..1742)
                     /gene="ilvD"
                     /locus_tag="VQO19_001876"
     CDS             complement(39..1742)
                     /gene="ilvD"
                     /locus_tag="VQO19_001876"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HET1350094.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(1975..2907)
                     /locus_tag="VQO19_001877"
     CDS             complement(1975..2907)
                     /locus_tag="VQO19_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HET1350095.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(2904..3761)
                     /locus_tag="VQO19_001878"
     CDS             complement(2904..3761)
                     /locus_tag="VQO19_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET1350096.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRIKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            complement(3765..5111)
                     /locus_tag="VQO19_001879"
     CDS             complement(3765..5111)
                     /locus_tag="VQO19_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET1350097.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFITKPSAKEE"
     gene            complement(5124..5408)
                     /locus_tag="VQO19_001880"
     CDS             complement(5124..5408)
                     /locus_tag="VQO19_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET1350098.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(5412..7442)
                     /locus_tag="VQO19_001881"
     CDS             complement(5412..7442)
                     /locus_tag="VQO19_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET1350099.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            7658..8665
                     /locus_tag="VQO19_001882"
     CDS             7658..8665
                     /locus_tag="VQO19_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET1350100.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            8668..8868
                     /locus_tag="VQO19_001883"
     CDS             8668..8868
                     /locus_tag="VQO19_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET1350101.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            9020..9202
                     /gene="rpmF"
                     /locus_tag="VQO19_001884"
     CDS             9020..9202
                     /gene="rpmF"
                     /locus_tag="VQO19_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HET1350102.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            9218..9367
                     /gene="rpmG"
                     /locus_tag="VQO19_001885"
     CDS             9218..9367
                     /gene="rpmG"
                     /locus_tag="VQO19_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET1350103.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(9846..>9955)
                     /locus_tag="VQO19_001886"
     CDS             complement(9846..>9955)
                     /locus_tag="VQO19_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET1350104.1"
                     /translation="TVSGQWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
BASE COUNT         3233 a         2102 c         1614 g         3006 t
ORIGIN      
        1 gacgttgacg tgatttgaag agattttcga gtatgagttt attttttacc tgacttgtcc
       61 atattccaga agtctgtcac ggctccgcgt gaagcagatg atacgatgtg ggcatattta
      121 ccgaggacac cacggctgta aagtggtggc aaggttgttt ctgccttgcg tttttcaagt
      181 tcttcttcgg atacggccat ggaaatttct ttggtatctt ggtcaaccgt aacgatatcg
      241 ccggtacgga gataggcaat tggtccacca tcctgagctt caggagcgat atgtccaaca
      301 accagaccat aagtaccacc agagaaacgt ccgtccgtca agagggccac cttatctccc
      361 tgacctttac caacaatcat tgaagaaagt gacagcatct caggcatacc aggaccacct
      421 ttaggtccaa caaaacgaac aacgactaca tcgccatcaa cgatttcatc tgtcagaacg
      481 gcctgaatcg catcttcttc tgagtcaaag accttagctg gcccaacgtg acgacgcact
      541 ttaacacctg ataccttggc aactgcaccg tcaggagcaa ggttcccgtt caagatgata
      601 agcggaccat ccgcacgttt tggattttca agtggcatga taactttttg gcctggagtc
      661 aagtctgcaa agtcagccaa gttttcagct acagtcttac cagtacatgt gatgcgatct
      721 ccgtgaagga aaccatttgc caacaagtac ttcataaccg cagggacacc accgacttcg
      781 tagaggtctt ggaagacata ctgaccagat ggtttcaagt cggccaagtg aggcacacgt
      841 tcttgaatcg tattgaagtc ctcaagtgac aagtcaacat ttgcggcatg ggcaatggcg
      901 agcaagtgaa gagtggcgtt tgtagaacca ccgagagcca tcgttacagt aatagcatct
      961 tcaaaggctt cacgagtcaa gatatctgat ggtttgagac caagttccaa catcttaaca
     1021 acagcacgtc ctgctgcttc gatatcttct ttcttatcag ctgattcagc tgggtgagag
     1081 gatgaccctg gcaaactcat ccctagaact tcgatagcag ttgccatggt attagcagta
     1141 tacataccac cacaaccacc agggccaggg caggcattac attcaagacg tttcacgtcc
     1201 tcagctgtca tgtcaccgtg gttccatttt ccgatacctt caaagacaga aaccaagtcg
     1261 atatctttac catcaagatt tcccggtgca atagttccac cataggcgaa aatagctggg
     1321 atatccatat tagcaatagc aatcatagat ccaggcatgt tcttgtcaca gccaccgata
     1381 gcgacgaagg catccacgtt gtgaccactc atagccgcct cgatggagtc cgcgatgatg
     1441 tcacgagatg ttagagagaa acgcatacca ggcgttccca tagcgatccc gtccgctacg
     1501 gtaatggttc caaactgtac aggccaagcg cctgcagatt tgacaccttc tttagccagt
     1561 ttcccgaaat catgcaagtg aatgttacat ggtgtatttt ccgcccaagt cgaaatcact
     1621 cccacaatcg atgtttcaaa gtccttatct gtcataccag tcgcacgaag catagcacgg
     1681 ttaggtgatt taaccatgct gtcatagatg ctactgcggt gacgtttatc taattcagtc
     1741 atcttatccc tcccatttca gtttttacta ttatagcaca atttaaaggc aatgaacaga
     1801 ataaaattct tgaattttca gaaaattcta tacgcatgtg aaatatttaa aattaaaaac
     1861 aacaaagcgg attagtgcac tttctgatga ccagaatatg ctttttaatc cgctttcttt
     1921 aaataacgta atgtaatttt tacagaaatt ctttcagata agtgtattta acatctatct
     1981 tgcattataa atttctagaa ccttctcttt tatattcgat tcactcaaac catactcatt
     2041 aagaagataa tccattttcc ctacttgacc aaatctttct tgaacaccca tccgatgaat
     2101 ttttgttatt ccatcatcag agaataattc acataaagca ctgccaattc cacctatctg
     2161 attgtggttt tctacagtaa atatagtttt tccacttaac attgttttta tctgttctgg
     2221 tatcggtttg attctaaata aatctatcac acctactgaa taacctaatt tagacagttc
     2281 atctgcaact cgaatacttg gagcaaccat tataccagaa gcaacgatta caagatcttc
     2341 accatgcctt aactcaatgt agcctttaga aaaatcttct ccaccttgat acacaggaac
     2401 tggagctttt ctaattgttc gaatatattt tagtcctttt aagtctaatg tctggttcaa
     2461 tatttcacga aattggatat catcagttgc ttcaaaaatg atcgatttag gaattaaacg
     2521 taacaatcca atttcttcaa atggcatatg tgtcccacca ttcatttctg cagttactcc
     2581 tgcatctgat ccaatcacag tggcatccaa ttgtgcgtat ccaagagaaa taaataattg
     2641 atcaaatact cttcgtgaag caaaaggacc aaatgtatga agataaggtc taaacccctg
     2701 aatagacaag cctgctgcaa ggccgaccat ttctgcttcc ataatcccaa cattcacata
     2761 acggtctcca aagtcctttt caagattatg agtagccatc gaacttgaca gatcggcttc
     2821 taagactact atatcagaat aactttgatt agcctctaaa aggaagtctc tatatacatg
     2881 ccgtaattct ttcgtacttc tcatcattct gtttcctcca attcctgact taatctttct
     2941 acaactgaag ttaacatttg tctctcctct acagtagggc gaagatgatg attggatttc
     3001 atttcttcca gctcttgaac cccttgacct ttaatagtat ctaatacaat gcacttaggt
     3061 gatgaattat ttgactgttt taattggaca atcccttcat aaatttctct aatatctgaa
     3121 cccttgatcc taatggattc aaatccaaat gctgaaaatt tttctacgaa atcacctgga
     3181 ttacaaatat cctttgtaaa accatctaat tgttttttgt tatcatcaac aaatacaatt
     3241 aagttggata actgttgatg agaagcaaac tgtatagcct cccaacattg tccctcattt
     3301 aactcaccat ctccaacaat agcataagta taaaagggac tctttcttat tctctgacca
     3361 tatgcaagtc cagttgcaac actaattcct tgtcctaaag agcccgttgt catatctatg
     3421 cctggcgtta gatttctatc aggatgagac ggtaatttgg ttccatttgt atttaaagaa
     3481 tataagaatt ctttgtcaaa gaaaccattc aaatagagtg tactgtatag agctggtcct
     3541 ccgtgacctt ttgataatat gaaataatct ctatctcgtg ctgcaaatat ttctggagtc
     3601 attggcatta tttcaccata aagcactgct aaaacttcta cgatagacag acttcctccg
     3661 taatgtccga atccaagatg attcaatgtt ctaagagtat ttaatcggat gttagtcgca
     3721 aattttctta actcatcttc cctattttta cttaaaatca tcccttattc ctcctttgca
     3781 gatggctttg taataaagga tactccaaac ataactgcta gaataagaac aagaccaatc
     3841 acaatgcctg cttgtgagcc aaattgattt aacattccta aaataattcc tgatagacca
     3901 aaatctgcat ctgagaaagt tgatccttgg aaaccaagtc ctcccaaaac tggcattaaa
     3961 aagactggaa gaaaactgat taaaatacct tgtaaaaatg ctccaatagt ggctccacga
     4021 acaccaccag atgcattccc aatgacacct gcagtcgctc cacagaagaa atgaggcaca
     4081 acacctggta agataacaac cgttcctgaa gcaatcataa ttgccatact tactaaacca
     4141 ccaacaaaac tagagataaa tccaattaga actgcattgg gtgcataagt ataaacaatc
     4201 ggacaatcca aagcaggttt tgaattaggt acaagacgct ctgaaatacc tttaaaggct
     4261 ggaacaattt cgcccaaaat aaggcgaaca cctgctaaaa taacaaatac ccctgctgca
     4321 aattgacctg ctaattgtaa agcataaact agaccacttg taccactact gatttctttt
     4381 tctatatatt ctgaccctgc aaagatagct acaataatgt aaataactgc catggataaa
     4441 gtgatactaa cagtactatc acgtaaaaaa gctaaactct ttggaaattt aatgtcctct
     4501 gttgattttg atttgtcacc gataaggcta ccagtaaaac cactcaacca atatcccaaa
     4561 gaactgaaat gacctaaagc caccttgtca tttccagtta attgaaccat atatttttga
     4621 acaaatgctg gggaaatact cataataata ccgagtgcta atcctcctag taagataaga
     4681 ggcaagctag taaagccagc aactgataaa atgaccgcaa tcatacatgc catatataga
     4741 gtgtggtgcc ctgttaaaaa aatatattta aatcgagtaa aacgagcgat taagatattg
     4801 aacaccatgc ctgcaaacat aatcagtgca gtagctgagc catatgttgt taaagctaca
     4861 gctacaattg cttcattatt cggcacaacg ccagataaat gaaaagcatg ctcaaacatg
     4921 gtaccaaatg gatttaaaga attttgtaca attcctgcac caccagatac aactaagaaa
     4981 ccaacaaagg tcttaattcc acctttaata atatcaggta atttcttctt ctgaagaact
     5041 aatcctaaaa ttgcaattaa agctactaaa atagctggtg tactaacaat atccaatatg
     5101 aacttcatca taacgctagc ctcctatata agtccttttt cttcacaaag tttagtaatt
     5161 aattctcgta gttcatccat atcaataata ctatttaaga tacgaacatc tccaagatga
     5221 ctagctgaat cagctagatc acgaccaaca atccaaatat cagctgcatt tggatctgct
     5281 ccacctaaat cataatgttc aacttctaca tccgaaacat tcaaatcact caatacagat
     5341 tcaatattca tctgtaccat aaaacttgaa cctaatcctg aaccacaagc tgtaccaatt
     5401 tttaacatta tctaatcctc ctgtttaatt atcattttaa tgtcatcata gttttttgat
     5461 gatattaaag tttgaacatg atttttatct cttaaaattg ttgttaaatg tgacaaagcc
     5521 tttaaatgac tctcattatc aatggctgca atacaaatca acaatcttac ctcttgttct
     5581 ggattatcca ataaataaat cggttcttcc aaaactaaca ttgacattcc tatttcattc
     5641 acaccttcat ctggccgagc gtgaggaatt gctactccct tccctaaatt aataaaaggc
     5701 ccaaactctt ctactttttg aatcattgcc tcagggtagt tctcagttat cttatcttga
     5761 tccaaaagcg gtttagctgc taaacgaatc gcctccttcc atcctaattt ttgcgaacta
     5821 acctgatagg tttctttggt aatgagttgt tctagcactg gtacaatttc ctttctatca
     5881 tttttttggt aaagataatt ctttaacgcc aatcttaatt ccaattcttg tgtaataatt
     5941 ccatatcttt tgacaatatt caggatttgt tcaatctcaa aatccccata ctctaaattc
     6001 ggaaaatctt ttaacactag ttctactagt tgtattgctt gctcttcagt catcataacc
     6061 gaaactagat aatttggctt ttctgtctcc acctttatgg tagaaaaaac catatcatag
     6121 tcactactag ctttcacctg taaatcatca atctttgagg ttcctataaa ctcaatttga
     6181 ggaaataatg ctaatagatt ctcttttaac atcaatgaag aactaacacc attaggacaa
     6241 atgattgctg ctttatagca tttttgaggc aaagtatctg ctttctttaa ataacctccg
     6301 aaatggataa caaaatatgc tgtttcacta tcaggtatgg gattgtcaat agcgtccatc
     6361 aagggcatca aagaatcttt gactaattca aataaatcag gataatgttc tttaacatgc
     6421 aatacatatt catttgaact aggtaggccg aactttaatc tatagtaagc cggtataagg
     6481 tggcggcgaa gattttctct caatccttcc ctttgtttaa aatgtaacaa agaaatatct
     6541 tccattctac ttataatagc ctctgttaat tgattaaagt aaaccggagc aacatctact
     6601 tcaccttcaa agcaacttga taataaaacg gtgatatagc gataatcatc ctcagaaaac
     6661 accgtatcta taattcccaa atcaaccact gtatccaata aaatagtcgt tatatcttga
     6721 ataacaggag atactaatgt ctctgaaaga catactcttt caacatccct ttgataccta
     6781 cacagaatga atactaaacc gaaaaggcaa acttttaatt gattaacaat aggtactagc
     6841 tgtagcttct cataataatc tttaactacc tgatttatca aatcataagt taatgaatac
     6901 ccccaactgg ataaaacata atccaaaccc caaatcccta tggaggattc cagcaactca
     6961 ctaaccattt gaaaagctaa gcggtgctta ttccactctg aaccgtgtaa agtataacct
     7021 tttgctctac tgtaccctag ctccaaatca ttatctaaca taatctttct taatgattga
     7081 atatcagata aggttgtatt cttacttact ttcaaaaagt cttggtaatg attattcgat
     7141 ataaaatcta atcggcaaaa agtgtaaaga tagattaaag ctaagcgagt cgactttggt
     7201 aaaaccaatt catccgactt aataatatct gtcaaagact gcttcgtacg atttgataaa
     7261 ctatagcgac cttgtttttt atccagcact atccctttat tagctagata aggcactaaa
     7321 taatctattc cttctttgac ttcctttata ggtaagctca ccttaacaga taattcatat
     7381 aatgatagct cacaatgatc catcaaagtc atcaaaataa ctagtgctct ataatcaaac
     7441 atttctcttc ctttctaact acaattatag tgtaaaaatt ataagaataa aagagtattt
     7501 gagcacaata taatctcacc ttttaaaaga aattattggg ctgaaacttt ttagtgatta
     7561 ttgggctgaa actttttagt gattattttc aactttctat tgacttttaa aaacaaagtg
     7621 atatcattta gatatcaaat aataggaggt cattcttatg actgaaaaac tcatcaattc
     7681 aaaaccaaat ggtgtattcg cattgattct cattgaattg acaatcgtac ttggtatctt
     7741 tatatttata atgggtgttg gttcggaaaa catttttgga attattatcg gacctttact
     7801 aatcgtaatt gcaggtctag ctcatgctgg tttaaaagtt gtcaaacctc aggaagctct
     7861 ggttctgaca ctctttggta attatacagg taccatcaaa gaacctggtt tttactttgt
     7921 caatcccttc agcgtagcag tcaaccctgc aaaccacact cgacttggac aaagtggtga
     7981 tgttagcaca aaatctcctt ttttaggagc taaatcatca aatgacaatg atgtaaatct
     8041 tgaaattggc aagaaacaga tttccctcaa agtcatgacc ttgagcaatt ctcgtcaaaa
     8101 aatcaatgat tgcttaggaa accctgtaga aatcggtatc gcggtaactt ggagagttgt
     8161 cgataccgct aaggcagtct tcaacgttga taactacaaa gaatatcttt cattgcaatg
     8221 tgatagcgcc ctccgtaata ttgtccgcat ctatccttac gatgtgtctc ctaatgtgga
     8281 tactacgggt gacgggcaag cagatgaagg tagtctccgt ggctctagcg aaattgttgc
     8341 taaccgtatt cgtgaagaaa tccaaagtcg tgttgaggat gctggcttgg aaatccttga
     8401 agcacgtatc acttacctag cttatgctcc agaaattgct gccgttatgc ttcaacgcca
     8461 acaagcatct gccattattg atgcacgtaa gatgattgta gatggtgctg taggaatggt
     8521 tgaaatggca ctagaacggc tcaatgaagg ggaattggta gaacttgacg aagaacgaaa
     8581 agctgccatg gtttcaaatc tccttgtcgt tctttgtggc aatcatgatg cacaaccaat
     8641 tgtcaacaca ggaagtcttt actaaagatg gctgaagcta aaaaaaagca gatccccctt
     8701 cgactctcaa caaagttata cgctgcactc gcatcatggg cagaagacga ctttcgttca
     8761 gtcaatgggc aaatagaata tctcctcaca gagtgtgtca agcaacggaa aaaagacgga
     8821 aaatacgtat cagaaaccat tgacgaacca tttgagattg atatttaaca ccttctcctg
     8881 tctgccgtgt cggataggag aattttttca tctttttttg tcaagtaact ttactttaca
     8941 aaaaaaatgt gttatcctag tatggttgat gaaaatcagt agattgaatc gaatataaat
     9001 acctaaagga gaaatcaaaa tggcagtacc tgcacgtcgc acttcaaaag cgaagaaaaa
     9061 caaacgtcgt acacactaca aagtaacagc tccatctgta aactttgacg aaactactgg
     9121 agattactca cgttctcacc gtgtatcact taaaggatac tacaaaggac gtaaaatcgc
     9181 taaagctgca tcagctgaat aatagaaggg agatactatg cgcgtaaata ttacacttga
     9241 acacaaagaa tctggtgaac gcttgtacct tacttctaaa aacaaacgta acactccaga
     9301 ccgccttcaa ttgaagaaat actcaccaaa acttcgcaaa cacgttgtgt ttacagaagt
     9361 gaagtaagca ttcaatacga atcaatacag aagaaaaacg cttgatcagc gttttttctt
     9421 tttgttaatt tcactatatt gcaagggaaa tcattcgaat gactacatta ttgaaataag
     9481 aatacggatt cggacaatta aaagcaagag gaactcaaat gtaagttggg gttccttttt
     9541 tgtatatttt tcaaataacg cctctacact atttgtagca aattcaccaa ctacagttgt
     9601 atcttagtta aaataagtta gaatatgtaa gtgagtacca gatataccaa gacatcgtca
     9661 ccatctaagg tatattcaaa atacaaaagt tgaccaacta gatttctgaa tatccttata
     9721 tatccattct taaaattggt ttaaatagcg tagtctttta aactagtttt gagaatccaa
     9781 aaaatcttcc tacatatgta agaagatttt ttagttcaga atgattagat ttagctaatg
     9841 gatacctatc ctacccactc accgttagca ttgactcgat agccatcggg tgtagtcgtg
     9901 tttactaata aatctcctga attataggta tagtaccatt gaccagaaac tgtaa
//
LOCUS       DAVAGB010000061         9894 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVAGB010000061 DAVAGB010000000
VERSION     DAVAGB010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9894
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.062"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            189..284
                     /locus_tag="VQO19_001887"
                     /pseudo
     CDS             189..284
                     /locus_tag="VQO19_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(537..1157)
                     /locus_tag="VQO19_001888"
     CDS             complement(537..1157)
                     /locus_tag="VQO19_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET1350105.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1157..1639)
                     /locus_tag="VQO19_001889"
     CDS             complement(1157..1639)
                     /locus_tag="VQO19_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HET1350106.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1639..2481)
                     /locus_tag="VQO19_001890"
     CDS             complement(1639..2481)
                     /locus_tag="VQO19_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HET1350107.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDFLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2576..3376)
                     /locus_tag="VQO19_001891"
     CDS             complement(2576..3376)
                     /locus_tag="VQO19_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HET1350108.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     TYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3520..4899
                     /gene="glmU"
                     /locus_tag="VQO19_001892"
     CDS             3520..4899
                     /gene="glmU"
                     /locus_tag="VQO19_001892"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HET1350109.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4909..5454
                     /locus_tag="VQO19_001893"
     CDS             4909..5454
                     /locus_tag="VQO19_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET1350110.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELKKK"
     gene            5466..5780
                     /locus_tag="VQO19_001894"
     CDS             5466..5780
                     /locus_tag="VQO19_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HET1350111.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKNHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5797..6489
                     /locus_tag="VQO19_001895"
     CDS             5797..6489
                     /locus_tag="VQO19_001895"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HET1350112.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVCGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLNQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6566..7057
                     /gene="rocS"
                     /locus_tag="VQO19_001896"
     CDS             6566..7057
                     /gene="rocS"
                     /locus_tag="VQO19_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HET1350113.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7155..7745
                     /locus_tag="VQO19_001897"
     CDS             7155..7745
                     /locus_tag="VQO19_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HET1350114.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            7754..9517
                     /locus_tag="VQO19_001898"
     CDS             7754..9517
                     /locus_tag="VQO19_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HET1350115.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVITCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQENPEYTDLLLKKALEFFEF"
     gene            9731..>9894
                     /locus_tag="VQO19_001899"
     CDS             9731..>9894
                     /locus_tag="VQO19_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET1350116.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYSWLKLKEK
                     TGELNHQVKGT"
BASE COUNT         3088 a         1714 c         2095 g         2997 t
ORIGIN      
        1 aagacttttt gaccagcctc attttttaac ttgatactca gtgaaaagca aagattaaac
       61 taggaagcta gctgtaggct gctcaaagaa cagctttgag gttgcagata aaacttgtga
      121 ggtaaccaac atatataatg tgaagctgac gtggtttgaa tagattttag aagggtatga
      181 gtctggaagt tttaatggat aatgcaagat tccatagaat gggtaagcta gagttcttat
      241 gtgaagagtt tgggcataaa cttttacctt ttcctcccta ctcatcttag tatagaaaag
      301 tgaatctaaa atagtacata actgcttcta aaacattctt ataaattgat ttaaattctc
      361 aaatcatatt attcagttct tatttcattt tgctctacaa tcctgttgag aagacacgtg
      421 ttcatatcaa aaaggtattg gcaagttgca ataccttttt acgaggctct tttatcttat
      481 ttttgtttca actgactata tctcctatgg ttctagttca gaaggctagg ctataattat
      541 gattgataag aagtatcatt ccaagtattg agagtgaatg tttcaaaatc atgggtttct
      601 ataatggtca ggctggcatt tgctagaccg ccatctttac gaagaagtgg ttctttatag
      661 cctaggagag tacgaagact ggcagtaaga ttggcgccgt gtccgacaat tagaatacgt
      721 tcagctggac tatcttttaa tgatttgata aattggatgg tccgttgagt tgtactatag
      781 agggattcgg ctccgaacat tcgagtgtca aattgagcaa gatttgaacg aaaagcctgg
      841 atttgttgcg ggtaaatagc ttccaaggtt gcaattttca aaccttctaa cttcccaagt
      901 tgccattcac ggagattagg aacgatttct aaagaacagg gggtatagag ttgactttgg
      961 ataatctcag cagatttgac cgctcgaggt aaatcacttg aataaatctg atcaaaagga
     1021 atttccttga gatactgacc aagtcgtttt agggtttcaa tggattcagg aagaagagga
     1081 gaatcaccac tagcaccttg aaaacgacct tcttggttcc agagggtacg accgtggcgg
     1141 acaaagtaga gtttcattac ttgatgtcct ccaaaatatc tacaaagtct gcctttacaa
     1201 agctagccaa gtcttgtggc gcgacgataa tgctgtgtcc gacttcgcct gcagagacaa
     1261 tcatttgatc caaatctaga gcaattttat cgataaaaat gggataattg tgtttctgac
     1321 gaattccgac aggattattg gctccatgaa tgtaaccagt tgttttttct aagtcctttt
     1381 gtggaatcat gctcactttt ttattgccag aaattttagc tagtttcttt tcagacaagt
     1441 gctgagtgat agggacaatt ccgataatcg gtccggtctt gtctcccaaa agcgccaagg
     1501 ttttgaaaat ctgatctcgt tcataacctt gaggaagctc tccttctagg gcattgattt
     1561 gaatcccctg atgagggata gctgctttag ataggatttg ttccaccaat gtttttttga
     1621 ttttaacttt ttttgccatt atttatattt atcctccaat tgactcatcc aaataccaag
     1681 ccagattccc agcgcaaaga agaaggcgat gatgacataa ccgacaagtg aaagtcctgt
     1741 gtattggata ctttcagcgt ttcctgcatt tggaattaag atcaaaaggg tacttgatag
     1801 gacgataccg atgatgaaat gatagacacg tgagtggtag ttgtttaagg cataatccat
     1861 caattttgaa aaaacgatga gagttgcacc tgcaccaatt ccaatcggaa agaaggttcc
     1921 caagaaatca aaagttttaa aaccagtcaa cataggagca tagagtccca aaatcaaaag
     1981 taaatttgat gggctgaggc caggaaccaa gacgccaagg gccaatagtg cgcctgctag
     2041 gacgaagtta agaaagctgg cgcttaaggt tccaacgaca aaatttaagg catagagtcc
     2101 taatccagaa atgataaagg ttgtccataa ccaagctaaa tcaatcttgt ctcggtcaga
     2161 ttctcgagtt gattctttga ggaggctagg aactgtaccg ataatagctc ccgcaaagct
     2221 ccataataca aaaacctgat aattttcaag caggtattca atcgggtagg aaaataagcc
     2281 gattcccaga agcataccga tggcaactgg aataaagtac aaaacatttt ctttaaagtc
     2341 tttaaaggga tgggccagaa agccaatcat tcgttcatag attcctaaga ttgctgctag
     2401 aacccctccg gaaattcccg gtaggataaa tccaagagca attacaatcc ctttaataac
     2461 gcgtgctaac catgagagca tatatttcct ccaactattt ctatttcaaa aaatccttac
     2521 tatattgtat cacaatcaga cacaaaaaga aaaagcaaat gataaacaaa tgcttttaag
     2581 gttttaaaaa aagttttcga aaggtttctt ctttattttt taagggagag ataacgttga
     2641 tatctaaatc gtggtcaaag ccggcaattt ttcctttaga tgtgtattgg tgaatatcat
     2701 aatctaaatc agttttagga ctgctctcca aaaatcctga gtctgagccg taggacggaa
     2761 tccaaacaga ggtaaacttg cctgtatcaa tactgtgttc ttccatgaag tagacaccaa
     2821 cgtagatgcc gatgttttta gcacctagtg atgctagttt tgctcgaaag ttttcgacac
     2881 cttcgttcat attagacatg gttttgtctt ccacgtcaag ccaatagtaa ctagggctgt
     2941 aaggagaggc agcattgtag aaaacttcgg cagccttttc catttcttgg acactttttc
     3001 cagctacata agcgtagaca gcaactggga cattccgctt ttgaagttca gtgatatgac
     3061 tcttataggt cttgtctatt ccattgataa atgaagcatc attttctttt gttgtttgag
     3121 caccactgtg aacacgaaca atagcacctg aaatattttg tgagagggca tcgtagttga
     3181 tttcctcagg acgctgccag ccagagaggt caataatcgg tttgtctaag tgtttcaaag
     3241 cctgtgcttc aatctgtgct atattggatt ttgttttaaa cgattggctg tcattaagtg
     3301 ggcgattgat gattaaaatg aacatcataa tcccaaaaaa actaaataaa ataagtggat
     3361 gaatttgttt tctcatatct tataattcta ccctaaaaat caaaaaaaat caaaaaaatg
     3421 ggttaaggaa gagactttag agcatttttt cattcaagag tgcggaatga tttgaaatat
     3481 ggtataataa aagggaattt ctacagaaaa gagaagatta tgtcaaattt tgccattatt
     3541 ttagcagcgg gtaaagggac tcgcatgaaa tctgatttgc caaaagtttt gcacaaggtt
     3601 gcgggtattt ctatgttgga acatgttttc cgtagtgtgg gagctatcca acctgaaaag
     3661 acagtaacag ttgtaggaca caaggcagaa ttggttgagg aggtcttggc tggacagaca
     3721 gaatttgtga ctcaatctga acagttggga actggtcatg cagttatgat gacagagcct
     3781 atcttagaag gtttgtcagg acacaccttg gtcattgcag gagatactcc tttaatcact
     3841 ggtgaaagct tgaaaaactt gattgatttc catatcaatc ataaaaatgt ggccactatc
     3901 ttgactgctg aaacggataa tccttttggc tatggacgaa ttgttcgtaa tgacaatgct
     3961 gaggttcttc gtattgttga gcagaaggat gctacagatt ttgaaaagca aatcaaggaa
     4021 atcaacactg gaacatacgt ctttgacaac gagcgtttgt ttgaggcttt gaaaaatatc
     4081 aataccaata acgctcaagg cgaatactat attacagacg tcattggtat tttccgtgaa
     4141 actggtgaaa aagttggcgc ttatactttg aaagattttg atgaaagtct tggggtaaat
     4201 gaccgtgtgg cgcttgcgac agctgagtca gttatgcgtc gtcgcatcaa tcataaacac
     4261 atggtcaacg gtgttagctt tgtcaatcca gaagcaactt atatcgatat tgatgttgag
     4321 attgctccgg aagttcaaat cgaagccaat gttaccttga aagggcaaac gaaaattggt
     4381 gctgagactg ttttgacaaa cggtacttat gtagtggaca gcactatcgg agcaggagcg
     4441 gtcattacca attctatgat tgaggaaagt agtgttgcag acggtgtgac agtcggtcct
     4501 tatgctcaca ttcgtccaaa ttcaagtctg ggtgcccaag ttcatattgg taactttgtt
     4561 gaggtgaaag gatcttcaat cggtgagaat accaaggctg gtcatttgac ttatatcgga
     4621 aactgtgaag tgggaagcaa cgttaatttc ggtgctggaa ctattacagt caattatgac
     4681 ggcaaaaaca aatacaagac agtcattgga gacaatgtct ttgttggttc aaattcaacc
     4741 attattgcac cagtagaact tggtgacaat tccctcgttg gtgctggttc aactattact
     4801 aaagacgtgc cagcagatgc tattgctatt ggtcgcggtc gtcagatcaa taaagacgaa
     4861 tatgcaacac gtcttcctca tcatcctaag aaccagtagg agcctatcat ggagtttgaa
     4921 gaaaaaacgc ttagccgaaa agaaatctat caaggaccaa tatttaaact ggtccaagat
     4981 caggttgaat taccagaagg caagggaact gcccaacggg atttgatttt ccacaatggg
     5041 gctgtctgtg ttttagcagt aacggatgaa caaaaactta tcttggtcaa gcagtaccgc
     5101 aaagctatcg aggctgtctc ttacgaaatt ccagccggaa aattggaagt aggagaaaac
     5161 acagcccctg tggcagctgc ccttcgtgaa ttagaggaag aaacagccta tacagggaaa
     5221 ttagaactct tgtacgattt ttattcagct attggctttt gtaatgagaa gttaaaacta
     5281 tatttagcaa gcgatttgac aaaagtggaa aatccgcgtc cgcaggatga ggatgaaacc
     5341 ttggaagtcc ttgaagtgag cttagaagaa gcgaaagaat taatccaatc aggtcatatt
     5401 tgtgatgcca agacaattat ggctgttcag tattgggagt tgaagaaaaa atagaggagg
     5461 tcagtatggg taaatcttta ttaacggatg aaatgattga aagagctaat agaggcgaaa
     5521 aaatttcagg tcctcctttg ctagatgata atgaggagac taagatttta ccaacctctt
     5581 cttcccgttt tggttatgcc aatcctaaga atcatggttt tagccaggaa accttgaaga
     5641 ttcaggtcga accatctatt cataaaagcc gtcgcattga aaataccaag agaaatgtct
     5701 tcaattctaa gttgaataaa atcttattcg cggtcatctt tctcttgatt ttgcttgttt
     5761 tagcaatgaa acttttgtaa tagaaaagga attgaaatga aaataggaat tattgctgct
     5821 atgccagaag aactggctta tctggtccag catttagata atgcccagga gcaagttgtt
     5881 tgtgggaata cctatcatac aggaaccatt gcttctcatg aagtcgttct tgtagaaagt
     5941 ggaattggta aggtcatgtc tgctatgagt gtggcgattt tggctgatca tttccaggtg
     6001 gatgccctta ttaatacggg ttcagctggg gcagtagcag aaggtatcgc tgttggggat
     6061 gtcgtgattg ctgacaaatt agcctatcat gacgtggatg tcacagcttt tggctatgct
     6121 tatggacaaa tggcgcaaca accgctttat ttcgaatcag acaaaacctt tgttgctcaa
     6181 atccaagaga gtttatctca attgaaccaa aactggcatc ttggtttgat tgctacagga
     6241 gatagttttg ttgcaggaaa tgacaagata gaagcgatta agtcccattt cccagaagtt
     6301 ttagccgtgg agatggaggg ggcagctatt gctcaagcag cgcatgccct caatctccca
     6361 gtcttagtca tcagagctat gagtgacaat gccaaccatg aagcaaacat cttttttgat
     6421 gagtttatta tcgaagctgg acgtcgctct gcccaagtct tgttgacctt tttgaaggct
     6481 ttagattaag cggaaatttg acagtttttc tagcttatga taagatttaa gtaaagaaaa
     6541 gctagaaaac gtttcagagg atattatgag tattgaaatg accgtcagtg agattgcaga
     6601 ggtcttagga ttatctcgcc aagcaatcaa taaccgtgtc aaagaattac cagaagaaga
     6661 cacagataaa aatgacaaag gggtaacagt tgttaccaga agtggcttga ttaagctaga
     6721 agaaatctat aaaaaaacga tttttgaaga tgagcctgtc agtgaagatg tcaaacaacg
     6781 tgaactgatg gagattctag tggatgagaa gaatgcagaa attcttcgtc tttatgaaca
     6841 attaaaagcc aaggatcgtc agttatcaga aaaagacgag cagatgcgta tcaaagaccg
     6901 tcagattgct gagaaagaca aacaattaga tcagcaacaa caattgaccc ttcaagccat
     6961 gaaggatcaa gaaaatctta agctagagct ggaccaagca aaagaagaag tccaatccac
     7021 taagaaaggc ttttttgctc gtttatttgg aggataatca aggagctgtt taggttaaat
     7081 gctaacctga tggcttcttt tgtttgtgaa tagtatagtt gattagaaca gagacagtag
     7141 aggagaggaa cagaatggaa cgattagaag attacattgc ttttgactta gaatttaatc
     7201 agcacgaagg acaaacacac ttgattcaag tatcggcagt gcgttttaga gatggtcggg
     7261 aaatcgatgc ctatgattcc tatgttcata ccagcgtccc tctaaaaagc tttatcaatg
     7321 gtttgaccgg gattacagct gagaccttaa aagatgctcc tccagttgag aaagtcttag
     7381 aagaattcca agagtttgtg ggttctttgc tgatgatagg ctacaatgct gctaaaagtg
     7441 atttacctat tttagcagag catggtttag actatagcca acagtacaag gtggatttgt
     7501 atgatgaagc ttttgaacgt cggagttcag atttacatgg tattgccaat ctcaaattgc
     7561 aaactgttgc ctcatttctt ggatttcaag gtcagtctca taatagttta gaggatgctc
     7621 ggatgacggc gcgtgtttac gaatccttct tagagtcgga tcaagctagg gaattgttag
     7681 agacagaaag tagcttatca aacaatcctt ttggtgtctt ggacttgtct caattatttg
     7741 actaggagtg cctatgaaac ctgaaaaacc taaaaaattg ggtcttaaac agatttacct
     7801 caatcttgat aaaatcctct ttctattttt cttgattttt atgatagtgg agtatttgtg
     7861 ggtaccattc aattcatggt tggctagctt cttattagat cagacaggtt atctttttat
     7921 ttcctataac aatgtcttag ccatccttac tcattctcca ttgattagtc tagctttttt
     7981 agccttgatt gtaattaacc ttctggttgc ttattttcaa ataggactcc tctttattgg
     8041 tgctcgtcat ctcctctata atgaaaagcg aaggctaatt gagtatatcc gcaaggtttt
     8101 ccatgaaagt tttggattta tgaaaaagct aactggcgct aaagccttgt ttatcttttt
     8161 ctatatagct atgctttttc cttttatacg gaaaatgctg aagatttatt atcttaataa
     8221 aatcgtcatt ccagagttta tccaagctta tttagaagat aaatattgga tgtggtggct
     8281 gagcatccta cttctatctc ttatctttct ctatgtctct gtcagattga tgtttgccct
     8341 tccgaagatt gtatatgatc agctgactgt tcgagaagca gtgatgttta gcttggagaa
     8401 aaccaagaag agagttactt tttatgcttg gaatttattt tacatcttgc tcaaagcaca
     8461 tttattattt tatcttcctt tgattccttt attattggct caaactttgg tagatgatat
     8521 cactcagaga gagtctctga ttcttggtat tttgaatttt gtcgtgatta aaaatctcta
     8581 ttatatggct ctgacttatt ttttggttaa atttgtttca tttttgacag gaaaggagct
     8641 ggatatgctt cctaggagag aaaaagatca catcgtgcga tggggtgtca taacttgtgc
     8701 cagtcttttc tttgccttag aaggttatat ttatctggag gctcccatgg ttcatctacc
     8761 tcaacttatt tctcaccgag gggtttccaa tgcaaatggg attcaaaata cagtagagtc
     8821 cttggaaact acagcacaac tcaaaccaga cttggtggag acggacgtgc aggaaacaaa
     8881 agatgggcag tttgtcatga tgcatgatgc taacttgaaa aatctagcag gtatcaataa
     8941 aagtcctcaa gacttaaact tggaggagct taaagggatt gatatttttg aaaatggcta
     9001 ccagactaaa atttcaagct ttgaagatta tctcagtcga gccaacgaac ttggtcaaaa
     9061 attactaatt gaaattaaaa ccagtaaaaa agatagtcca gacatgatga accgcttttt
     9121 agcccgttat gctgcaaagc tcaagattta tggacatcaa atccagtctt tagactacca
     9181 tgttgtcgaa aaagtaagac agtatgatgc cgaactgcca gtttatttca tcatgcccta
     9241 caattctgtc tttcctaaaa caagagcgac aggatatact atggagtact caaccttgga
     9301 tgaatatttt gtaagcaaac tatggacaac ggatcagaaa ctttatgtct ggactgtcaa
     9361 tgattcagaa gctatcagca aatctcttca cttaggagta gatggagtga ttacagatga
     9421 tttggaaaaa gttcagcggg aaatagaagt agcccaagaa aatccagaat atacggattt
     9481 gctcttgaaa aaagcattgg aattctttga attttagtaa taaaaaagag gaacggttgt
     9541 tcctcccatg ataggtaagt attcttgtga atgcttgctt ttttgtggtt gcaatccgtt
     9601 tacgagaatt gtttgtattg ttcttgtttc aatttacttt atagtgcttt gaagttggaa
     9661 tgctacacta taacttctaa aatatagtaa aatgaaccaa aaatagtaca caatgtggta
     9721 taatcttttt atggcatatt caatagattt tcgtaaaaaa gttctctctt attgtgaacg
     9781 aacaggtagt ataacagaag catcacacgt tttccaaatc tcacgtaata ccatttatag
     9841 ctggttaaag ctaaaagaga aaacaggaga gctaaaccac caagtaaaag gaac
//
LOCUS       DAVAGB010000062         9143 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVAGB010000062 DAVAGB010000000
VERSION     DAVAGB010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9143
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.063"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            355..1041
                     /locus_tag="VQO19_001900"
     CDS             355..1041
                     /locus_tag="VQO19_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET1350117.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNKLLMADISTFEEGKVAVESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            1042..1974
                     /locus_tag="VQO19_001901"
     CDS             1042..1974
                     /locus_tag="VQO19_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET1350118.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFSFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            1985..2914
                     /locus_tag="VQO19_001902"
     CDS             1985..2914
                     /locus_tag="VQO19_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET1350119.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPSAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            2928..4367
                     /locus_tag="VQO19_001903"
     CDS             2928..4367
                     /locus_tag="VQO19_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350120.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHIGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            4436..6013
                     /locus_tag="VQO19_001904"
     CDS             4436..6013
                     /locus_tag="VQO19_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET1350121.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPEINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            6073..7533
                     /locus_tag="VQO19_001905"
     CDS             6073..7533
                     /locus_tag="VQO19_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET1350122.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKVDILLNVEVNNIIYDSKNIKSLEILSNQEVKLIDSKVFIDATGN
                     ATIASASGADVYEKNSSYGCLMRVGGVDISKTIEHIEKTKQWNYIEGYNQWLEEVLAN
                     RKYRATGAVLKDPVSYDHAPMLSKDDHFMNDEKWNYIKERWEKFRFIYTLEVSLFRNE
                     LKKAVESGDFNFEIYHDDKSGVTMNGDGISYGSWGQNVALINVAKAFGFNPKYMEDES
                     HANILSRKYNLTFLSFLKKYVPGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPM
                     YTFKTMYSYQTPKEITYKSIVGGKLNNLFVIGKGAYQSESFRSQISCMLMGISSAAAA
                     KTIIEDKSNTLNINRDLFKSNLDILFTWEFSNWITD"
     gene            7555..8010
                     /locus_tag="VQO19_001906"
     CDS             7555..8010
                     /locus_tag="VQO19_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT domain-containing protein"
                     /protein_id="HET1350123.1"
                     /translation="MNDTNKNQYFVYEFDTSFVEMSYSQFFEGYCILFSKEPYPSLSD
                     MPMEFRKEFLMEMSILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRK
                     TVVHRYDSSVFSNPEFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            8515..8964
                     /locus_tag="VQO19_001907"
     CDS             8515..8964
                     /locus_tag="VQO19_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET1350124.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDISKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEETILYNFLSQMELSEYKVDDDWQ
                     QMNGEALFSIILKKNMLLLLEPNDAHKTGLLVEEPINIKKVVFKVKI"
BASE COUNT         3204 a         1182 c         1699 g         3058 t
ORIGIN      
        1 tccaaattag aaaaagactt gaaatactaa aaaaaaaaag tatactctaa ttgaaaacgg
       61 taacaaaact aatttagaga atgaaatata gagtatttct ctcttaaaag tttttggtga
      121 aacgagatgt agaagggaga tttagccaaa gagtctatta gtgctagaat aatagattag
      181 aattatagtg tattgaatct ataacagtac gccttaaatg ctaaaatatt tctataaatt
      241 aatttaactt tcctgatagg gctgttcata tcttatttca attcactata taaataaaat
      301 tgtagtagat gttattgaat tagtaaaaaa aataaaaaaa cggaggtttt ctgaatggaa
      361 actaaaaaaa ttaaaaattt aaaaggtcaa ataattgttt cctgccaagc gttagaagga
      421 gagccacttt atactccaaa tggaggagtg atgccgttat tagcaaaagc cgcctttcaa
      481 gcaggcgcta aaggtattcg tgctaattct gtccgcgata tttcagaaat aaaagaagaa
      541 gttgacttac caattatagg tatcataaaa agagattacg atggctttga accttttatt
      601 tcagcaacta tgaaagagat tgatgaatta gttagtgaag gagtagacat tttagctttg
      661 gattgtacta atcgttcaag accaggttat gataatatta ctgactttat tcatgatatt
      721 aaagtcaagt atccaaacaa attattaatg gctgatattt ctacttttga agaagggaaa
      781 gtagctgttg aatcgggagt agattttgtg ggtacgacat tatctggtta tacaccatat
      841 agccctaaaa aagataatcc tgattttgag ttagttgaaa gattggtaaa agagcttgac
      901 gtaccagtta ttgctgaagg aagaataagt actccggaac aagctagaaa aatgttagat
      961 ttaggtgctt acgcagtggt tgttggagga gctatcactc gtcctttgga aatagcgaag
     1021 aagtttattg aggtagttta gatgaatcaa gaaatattaa aaaagagtaa gattcaattg
     1081 acagttgaac atattcaaaa atattggatt ttatatttaa tgatgattcc agcaactgtt
     1141 ctactaattt tatttacgta tggaccaatg tacggcatta ttatggcctt tcaagacttt
     1201 actgtcttca agggatatac tggaagtcca tttgtcggtt taaaacattt tcaaagattg
     1261 ttctcagatc ctttgtttta tagattgttc aagaatacgt tcatggtagg ggttttagac
     1321 tttttattct ctttcccagc tccgcttatt tttgcactca tattaaacga agtcagaaaa
     1381 gtaagattta agagtgtagt tcaatctatt agttatcttc ctcattttat tcccctagtg
     1441 gttatggttg gtattatttt tgaactattt ggttcatatg gtattattaa cagtttactt
     1501 tcatcacttg gaatggagcc aataagtttc tttacaaaat ctgaatggtt cttgcctctc
     1561 tacattggtt caggagtatg gaaaacaata ggttggggtt ctatcattta tatgggagca
     1621 ttaaccaata tagattcaac tttatatgaa gcagcagata tggacggggc taatagatgg
     1681 cacaaaatgt ggcatgtaac tctaccaagt ttaagaccta cagtagttac tttgtttata
     1741 ctaaatgctg gtggtatcat gcaagtagga tttgaaaagg tattcttgat gtctagtcct
     1801 gcaacatatg aagtatctga tgtattatct acttatgttt atagacaagg tattttaaat
     1861 tctgatttca gttactcagc tgcagtagga ttatttaata acatagtagc tttgttattt
     1921 gttttattag ctaataagat tgctaaaaaa cttggcgaag aaggaattgt ataagggggg
     1981 taaaatgatt ttttcaaaaa atacaaaaaa gagtaataga gacaaagaaa ccttcgttga
     2041 ttatctcttt atattcattt taataataat aaccttactt atgttgtatc cattatggtg
     2101 ggtagtgatg acgtcacttt cagaaccagt ttggctatct aaaaacgttg ttaaattatt
     2161 tcccttaaaa atagatatta ctgcatataa gtttattttt ggggattcta aactatggca
     2221 agcatatggt aatagtgtat tgtatgctgc actatctaca attgttagtg ttgcggtatg
     2281 tagtatgtat gcctatccac ttacaattcc tgaaattagg ggtaaaaaat tctggaatac
     2341 tcttattttg attccaatgt tctttagtgg aggaatgatc ccgctttata tacaagttgc
     2401 aaacctcggt ttattgaata ctgcttgggc tcttgtttta cctagtgctg tttctacata
     2461 ttatataatt ttgtttagaa cacagtttaa atcaatccca atggagcttc gtgagtctgc
     2521 tagaattgat ggggcaagtg aatttagaat tttttggaat ttagtattac cattatcaaa
     2581 agttattttc atgattatag cactttattg catagttggt tcatggaata gttttactcc
     2641 tccattactt tatttgaatg acgacactaa gatgccttta tctatttatt tgagaaattt
     2701 agttgttaca aatacaactg atactgctga attatcactt tctgcaggta atacatatta
     2761 ccaacaaatt gctgctcaag gtggaggtat tggtatgcgt attgctatta agatgggtac
     2821 tattgttgtt agtgttattc caattatgat gatttatcca tttattcaga aacattttgt
     2881 taagggaatc ctgctaggtt ctgtgaaagg ttaataaggt aattattttg caaaatttaa
     2941 aaaaatatct tttattagat agcggtttag tagttgggta tacattagaa aatgctcaat
     3001 taaaattaaa taagctaaaa aaagatactg aaaacaatcc actatttggt gaagagtatt
     3061 ttgccgaaaa tcctaaatta tgggaagttc gttttgataa ttcatatcca aacgttatct
     3121 atgataaaga attgaaatta tatagatgtt ggtatcaaac atttgttagt gatgaagcaa
     3181 gcgaagagac tcctttagca gaacgtggag agaaggaata cattgtcaag tcatctagaa
     3241 tgacagcact ttgctatgct gaaagtaaag atggagtaaa atgggaaaaa ccaaatctca
     3301 atctagtaaa atttaaaggt tcaaaagata ataatattgt tctgatgcat gcacacggtg
     3361 caggtatcat gctagatgaa caggagttgg atcctaagaa acgatataaa ttagtttcaa
     3421 aattagaatt ttctccgaat cttcattaca tggttgttgt tttttcagaa gacggtattc
     3481 attttgacga acctattcca tggaaaaaat ggaatcctgc agcagatagt cataattttc
     3541 catttagaga tccaaaaact ggtaaatacg ctgttattac aagaacctgg gcaaataacg
     3601 tacgtctaag tgcaattact ttcagtgatg attttattaa ttggtcagaa cctaaagaaa
     3661 tccttagggg agatggattt gaagatcaaa tttattctat gccagtaatt tcatacgcgg
     3721 atatctattt aggttttgct tcaatgtacc acgaaggcga cactttaaat gaaaactatg
     3781 ataaagtaga cttagaattg aaattctctg ctaatttgga acaatgggat agtgtatgta
     3841 agggcgacta tctcattgaa aggggaggtg gagtataccc gcagaatgct gattttgatg
     3901 ctagttgtat tttcacggct gctccaataa ttgaagatga taagatttgg ttctactata
     3961 tgggtggaaa tggtaatcac attggcttcc gagaaagttc attagctaga ggatatatta
     4021 agaaagacca atttgcttat tatactaata agagagaagg aattccagct aaaatatcta
     4081 cagttagctt ccaaacttac gatgatgaaa tttatatctt agctgatatt cctgaaaatg
     4141 gttatattaa agttgcggta ggtactaaat acggtaatgc ttattcagat tttggtcagg
     4201 aagatatctc tcttgttcaa gtttccgatg gtaagtataa gttggaattt aataaaaaat
     4261 ctatcttaga tttaggtaat tctccagttg cgttcaaatt tgaaatcgag aatgcaaaat
     4321 tgtatggtat tgaaggtagt attcagcaac actatctcaa atattaacca gaataattcg
     4381 ttaacaaata atctctatat tagtggagat agatatataa aatggaggtc ttattatggt
     4441 aaagcttaat aaggtattaa aagggagtgt tgcattcctg agtgcaagtt tattgctagc
     4501 agcttgtggc aataacgcta attcaaagcc cgctgaaaaa acagctgatg gtaaaacgaa
     4561 aatttcgttt ctatctacat ggcaaattaa tgatgttcgt ccgcctaaag atgaaacact
     4621 tgttggtcaa tggttagaag aacagctagg tattgatatt gatcttgtaa ctattcctgg
     4681 cgagggagta agttctaaag taaattctct tattactagt aaccagttac cgactgtttt
     4741 gttgacaaca ggagataaga gtgatatcgc tggtatcaac aaacttggta aacagggtgc
     4801 attcttagat ttgtcacaac acatggacaa actaccaaac tataagaagt accttgaaaa
     4861 aaataatgca ttagctcaaa tagaagatga tgaaaaacat atttatgctt tcacaaaatt
     4921 ctttactgat gagaatatca tgtatactac accaattctg agaaaagact tacttgttgg
     4981 ttcagaattt gaagatcttt caaaaattaa aactgttgat gactatacaa aagttttgaa
     5041 atatttgact gaaaaacaag gttctccagc atttattcaa cgtaatggct atgaaggctt
     5101 catgaagcga gttacaccat tgtggaattt aagccatcgt acatactatg actatgaatc
     5161 agattcatat aaacatccag ttgaacaacc tcaattgaaa caattcgttg aatggttgaa
     5221 agaattacgt aaagataacg tacttcaccc tgactgggca gttatgaaag atgaaacttg
     5281 ggaaggtcta ttggcttcta acaagggttc attcactgtt gaccgtatga atatcattgg
     5341 agataataac tttgataaat catttgattg gcagccactt gtttatccag aaattaatgg
     5401 aaaacgttat ttgcaaccga aaacaccgta catttctgat tcaggttggg taatcaatgc
     5461 caatgcacca aaagaagaaa ttgataaagc gttagaattc tttaatttct tatacgctga
     5521 tgaaaatcaa gaaaaacttg ctattggatt tgaaggtaaa acatttacac gtgaaaaccc
     5581 taatactcaa gcaggtatta aatggttgat tcaaatttac ggtgaaaatg ctggaaatga
     5641 taaagcagaa ctgctgttta aacatggtaa ccaagcattt actcgcgttc aaactaaatt
     5701 agatattgag gcacagccag gaacattccc taaagttatg tatgatcaag tagataaaat
     5761 taagaaagat ttaggtggtt ttagaccaga tactccggtt ctttccttta caactgaaga
     5821 attagatgtt ttaactaaat ctgaagcagg attaaatact ttctttgatg aaaatattat
     5881 taaattcatt gaaggacaaa gagatatgag tgagtgggat tcatttatca atgaagctaa
     5941 atctaaagac ttggataaag ttacaaaagt atataatgat gcctacaaac gtgtcaaaga
     6001 tagaatgaaa tagactaaat ggtagctctc tggtttttca gagagctact actgcctgag
     6061 ggggagtaag ctttgtatga tgtagtaatt ataggtgcag gaagttcggg cgcattggct
     6121 gcaattgctt cggggcgtct agggttaaaa acttgtctaa tagagaaggg aagtagaatt
     6181 ggtggagttc ctattaatac actaatgggg tcatttgcta atctatattt tgatgattct
     6241 ggtagagtaa atgcaagtaa aattgttggg gaattaatag aacgtattat caaaaaaggt
     6301 ggtactgtct ttaactctat ggaagaattg atgaatgtaa atgattttta tcagattaca
     6361 attccctatc aaccagaagt ttatgaatcg gttttaactg atatgttgat tgagtctaaa
     6421 gttgatattt tactaaatgt tgaagttaat aatattattt atgatagtaa aaatattaaa
     6481 agtcttgaaa ttttaagtaa tcaggaagtt aaattgattg attctaaagt ttttattgat
     6541 gctacaggga atgcaacaat tgcttctgct agtggagctg atgtttatga aaaaaattct
     6601 tcttacggtt gtttaatgag agttggagga gttgatatct caaagactat agaacatatt
     6661 gaaaaaacaa agcagtggaa ctatatagaa ggatataatc agtggttaga agaagtatta
     6721 gcaaatcgaa agtacagagc cactggagca gttttaaaag atccagtttc ttatgatcat
     6781 gcccctatgc tttcaaaaga cgaccatttt atgaatgatg aaaaatggaa ttacattaaa
     6841 gaaagatggg aaaaatttag atttatttac actttagaag tatcactatt taggaatgaa
     6901 ttaaaaaaag ctgtagaatc tggggatttt aattttgaaa tttatcatga tgataaatct
     6961 ggagtcacta tgaatggcga cggtataagc tatggttcat ggggtcaaaa tgtagcatta
     7021 attaatgttg caaaagcatt tggattcaat cccaaatata tggaagatga atcacatgct
     7081 aatattcttt ctagaaaata taatttaaca tttttatctt ttcttaaaaa atatgtacca
     7141 ggttttgaaa attcttttat ccttgatcag ggaactagag ctactaacag atcatgtagg
     7201 cacattgata attcatctat gatggacgaa attcttgatt ttccaatgta tacatttaag
     7261 actatgtata gctatcaaac tcctaaagaa ataacgtata aatcaattgt aggtggaaaa
     7321 ttgaataatt tgtttgtaat aggtaaaggt gcttaccaat ccgaaagttt tagatcacaa
     7381 attagttgta tgttaatggg gatatcatca gcagcagcgg caaaaactat tattgaagat
     7441 aaaagcaata ctctaaacat taatagagat ttgtttaaat cgaacttaga tatattattt
     7501 acatgggagt tttctaattg gattactgat taacaaataa taagggaata ttaaatgaat
     7561 gatactaata aaaatcaata ctttgtttat gaatttgata ctagctttgt agaaatgtct
     7621 tattctcagt tttttgaagg atattgtatt cttttttcaa aagaacccta tccttcttta
     7681 tctgatatgc caatggaatt tagaaaagaa tttttaatgg aaatgagtat attaggtgat
     7741 gcgatgcttg aagtgttaaa tgcctataga attaattatg atatcttagg aaattcaaca
     7801 cctgtacttc atgctcattt atttccgaga tacatgtggg aagaggaaga gagaagaaaa
     7861 actgtagttc atagatatga ttcttcagtt tttagcaatc ctgagtttga atttactata
     7921 gaaaagcatg gaccaattat taaaaaactg aggtctgcta ttgatagaca ttatagagag
     7981 tatcaacaat tattagatga ttcaaactga actccacatt ttcgattaga tttaatacct
     8041 tgtatattac aactaggttg tggatgatat aattttttga aaaatatatt ttaggaatga
     8101 cttataaagc aattatatca gaggctatta aatcaatggc caaagcttat gctccttatt
     8161 cttattttaa ggttggagct gcgttagaaa ctgaagataa aaattttttc ctggatgtaa
     8221 tatagaaaat gttgcttttc tcctacttgc tgtgcagaac gagtatattt ttacaaagct
     8281 gtatttaaag gagaacgttc gttttcaaaa atatgtattg taggcggaaa aaaaggtatt
     8341 ttatcatctt ttatagcatc ttgcagggtg tcttgtcagg taatgataga attttgtaat
     8401 cttgattcat ttgtagttat attggctagt gatgttgata attataaagt atataaactt
     8461 aaagaactac taccagttag ttttaatcaa gaaaatttat aacaggaggg aactatggaa
     8521 ttagttgaat ttaaaaatgg acatgttaat acggttcatg agcatatcgc aataacgaaa
     8581 gtaaaagagt ttctaaataa tcatgatata tcaaaagata aaggtggcat acataaaatt
     8641 tctactgatt tcttttacaa tataattgat atggaaacta caactgaaga gaatagaccg
     8701 tgggaaagtc ataaggaata ttatgatgtc cattatctgt taaatggaga agaaacaatt
     8761 ttatataatt tcttgtctca aatggaattg tctgaatata aagtagatga tgattggcaa
     8821 caaatgaatg gggaagcttt atttagtatt atattaaaga aaaatatgtt acttttgttg
     8881 gaaccaaacg atgcacataa aacaggccta ttggttgaag aaccaattaa tattaagaaa
     8941 gttgttttta aggtaaaaat ttaactgaaa gtactttcag ggattaagaa ttttaaaata
     9001 tttaagaaat tgtattctaa agttctaaaa ttatagatat ttaatttaaa gcttgttaaa
     9061 atagaatagt aacactcatc tgctttcaaa aagcattcta gtccatctcc gattaacgat
     9121 ggactttatc acctccttct cca
//
LOCUS       DAVAGB010000063         8915 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVAGB010000063 DAVAGB010000000
VERSION     DAVAGB010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8915
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.064"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(209..1177)
                     /locus_tag="VQO19_001908"
     CDS             complement(209..1177)
                     /locus_tag="VQO19_001908"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET1350125.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(1322..1945)
                     /locus_tag="VQO19_001909"
     CDS             complement(1322..1945)
                     /locus_tag="VQO19_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HET1350126.1"
                     /translation="MPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPDSTFLNA
                     FESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIKDIGYIRTDL
                     PEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLAL
                     GTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(1927..2136)
                     /locus_tag="VQO19_001910"
     CDS             complement(1927..2136)
                     /locus_tag="VQO19_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350127.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKNGNCQRRF"
     gene            complement(2161..2658)
                     /locus_tag="VQO19_001911"
     CDS             complement(2161..2658)
                     /locus_tag="VQO19_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HET1350128.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(2731..4092)
                     /gene="radA"
                     /locus_tag="VQO19_001912"
     CDS             complement(2731..4092)
                     /gene="radA"
                     /locus_tag="VQO19_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HET1350129.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(4106..4621)
                     /locus_tag="VQO19_001913"
     CDS             complement(4106..4621)
                     /locus_tag="VQO19_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET1350130.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATSLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(4623..5066)
                     /locus_tag="VQO19_001914"
     CDS             complement(4623..5066)
                     /locus_tag="VQO19_001914"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HET1350131.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(5123..5219)
                     /gene="ffs"
                     /locus_tag="VQO19_001915"
     ncRNA           complement(5123..5219)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VQO19_001915"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5252..5719)
                     /locus_tag="VQO19_001916"
     CDS             complement(5252..5719)
                     /locus_tag="VQO19_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HET1350132.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(5920..7206)
                     /locus_tag="VQO19_001917"
     CDS             complement(5920..7206)
                     /locus_tag="VQO19_001917"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HET1350133.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(7437..7673)
                     /locus_tag="VQO19_001918"
     CDS             complement(7437..7673)
                     /locus_tag="VQO19_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HET1350134.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            7939..8720
                     /locus_tag="VQO19_001919"
                     /pseudo
     CDS             7939..8720
                     /locus_tag="VQO19_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8839..8912)
                     /locus_tag="VQO19_001920"
     tRNA            complement(8839..8912)
                     /locus_tag="VQO19_001920"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8876..8878),aa:Asn,seq:gtt)
BASE COUNT         2863 a         2135 c         1420 g         2497 t
ORIGIN      
        1 cctactagaa ttctccttag aaagcgtcga ttcaagtgct atcactgttc aaaaatgatg
       61 gtcgctgaaa cttctgatga cgtacagtca tatttcttct ctttttatta tatcacagtt
      121 ttaaatctag ctttactaga ttcaccgcta ctatctattt attcggaaaa aagacgaaaa
      181 aacctgagaa tcatctcagg cttggtcatt aaattttttt ctcaatatcg aaaagtggag
      241 aaagtggtcg tttttcatga atacgtacga tagcatcccc taggagatga gcgattgaaa
      301 tctgctcaat cttatcaatc aaacgctctt ctggaagata gatggtatcc aaaacaacca
      361 atttcttaat agctgatttt tggatattgt ccgtagcagg accagaaaga actgggtgcg
      421 tacagcttgc atagacttca acagcaccag cttccgcaag agcatctgcc gcatgacaaa
      481 tcgttccagc ggtatcaatc atatcatcaa tcaagataca agtcttgcct tcaaccttac
      541 cgatgatgtt cataacttca ctagtattca tcttatcaac gctacgacgt ttatcaataa
      601 tagcgataga tgttttcaaa aattctgcca acttacgagc acgagtcacc cctccatggt
      661 ccgggctgac aaccacatag tcagaaccaa ccataccacg acgctcaaaa taatctgcaa
      721 tcagaggagc acccatcaaa tgatccacag gaatatcaaa gaatccttga atttgcgcag
      781 catgcaagtc gatggtcaat aaacgatcca ctccagctac ttcaagcata tttgcgacaa
      841 gttttgaagt gattggctca cgcgctctcg cctttctatc ctgacgtgca tacccatagt
      901 aaggcatgac aacattgaca gattctgcac tcgcacgctt caaagcatct accataatca
      961 aaatttcaag cagattgtca tttacaggcg aactagttga ttgtaggata aagacgtgtt
     1021 tcccacggat tgattcttca atgttgacct gaatctctcc atctgaaaat tggcgaacac
     1081 ttgatttccc caactctatc ccaatctcct gcgccacacg ttctgccaat tctttattag
     1141 aagaaagggc aaacagcttt aaatcagaaa aagacatgat ttcctccggt atatatgtat
     1201 aacttgtgct tttcacaaga ttttccatct accattgtag cgctttttgc actatttttc
     1261 aatcaaaaat aaaagaaggg caccatattt gtacccttgc atcattcttt tgaaaaatat
     1321 tctaggtcat caactcattg tgtttctcaa caaagcaata agcatgataa aaaccataga
     1381 gagcaatagc cgtaaccact ggaatcgcta aaggcaactc tgtttccaac tccacaaaag
     1441 gagagttaaa caagaagtga gttcccaagg ctaaacctag aaaaataagg ccctgtttct
     1501 tgccaacctt ctgtccttta taggctctgt aaagcaagta aacacctact acagctagac
     1561 ctgaaaaagt ccagtgagag gcaattcctg agatgatacg ctctaaaatt cgcgaaatag
     1621 taaaatcaaa gccctctggc aaatccgtac gaatataacc aatatcctta atcatttgga
     1681 atcccaaacc ggaagcaatt ccaagtaaaa acaaagattt taattttcgc acaggaatca
     1741 aagccaaaac aaaaacaagt ggcaataatt tcaagggttc ttctaccaaa ggagccacaa
     1801 tagcactttc aaaggcattt aaaaatgtac tatctgggaa aagaaccccc agtaaatcat
     1861 ggatataagt attagcaaaa ctagacaacc agcctgaaag gaacatccct cccaataaag
     1921 acagaatcaa aaccttcttt ggcaattccc atttttccca atacggaaga gaaaataaag
     1981 agccggaatc atgtaaaaga gagctagaaa gatagaaact cccattagtc catattccgc
     2041 acctgacctc gaaccgtccg tatagtagat ggtttcatac tgtaaaccaa tacatagcaa
     2101 taaaataaaa ataaataaaa tactgctttt cttcatacac tttctttcta aatgaagtat
     2161 ttataattct acgactgtca tacttcctgt atcaacattg taaatggcac cagagataat
     2221 gacatcgtct ggtattaggg gagactcgat aagcagttgc atatcctcgc gtacactctc
     2281 ttctatatct tggaagggca agaagtcctg gtctgacaca tctacaccta attcctcttt
     2341 taaatactcc tgaaaaggtt cattttcaaa ggtctgagca ccacagtctg tatggtgcaa
     2401 taccacaatc tctcttgtcc ccatttgttg ctgggaaata actagcgaac gaatcatgtc
     2461 ttcagtcact cgaccacctg cattccgcaa gatatgagca tccccaagtg ccaaacctag
     2521 agcttgcgca acgtgcaaac gtgagtccat acaggtcaca atggctactc tggttttagg
     2581 tttaagtggc aaatttaact gcccatgtag ggcaacataa gcctgattgg cttgcataaa
     2641 ctgttcaaaa tacgacacga ttccctcctt gaaaatttga tagtcaaata tttctcctat
     2701 cttatcattt ttaagagaat ttgtcacgga ttatgcaaag acctttttca agacttcctg
     2761 aatcgttgtc acgccaatga cctgaatttc cttaggcaga gtgattcctg tcaaggaatt
     2821 cttaggtaca taaatcttag taaagcccag tttagcagct tcgttgatgc gttgctcaat
     2881 acgattcacg cgccgaatct ctcctgtcaa gcccagttct ccgacaaaac attcctgagg
     2941 attagttggc ttgtctttgt agctcgaagc aatagcaact gcaacagcca agtcaatggc
     3001 aggttcatcc aatttaacac caccagcaga tttgagatag gcatcctgat tttgcaagag
     3061 aagccctgcc cgtttttcca aaacagccat aatcaagcta gcacggttaa aatcaagtcc
     3121 tgtcgtagta cgcttggcat ttccaaacat ggtcggtgtt accaaagcct gaacctccgc
     3181 caaaatcgga cgcgtccctt ccatggttac aacgatggag gaaccagtcg ccccatccaa
     3241 acgctcttct aggaaaactt gactcggatt gagtacctca accaagccgc ccgactgcat
     3301 ctcaaaaatc ccaatctcat tagtggaacc aaaacgattt ttgaccgctc tcaaaatacg
     3361 aaaggtgtgg tgacgctccc cttcaaagta aagcaccgta tccaccatat gctccaacat
     3421 acgaggccca gccaaggttc cttctttggt cacatgacct acgataaaga tggcaatgtt
     3481 attggtcttg gccaactgca tgagttcagc ggtcacttca cgtacctgag aaacagaccc
     3541 ctgcacccct gaaatctcag gagacatgat ggtctggatg gaatcaataa tgagaaagtc
     3601 tggctggata cgctccactt ctgcacgaac actctgcata ttggtctctg catagagata
     3661 aaactcacta tcaatatcac ctaagcgctc tgcacgtagt ttaatctgct gggcagactc
     3721 ctccccactg acatagagaa ctgtccccac ttgggacaac tgggttgaga cttgtaggag
     3781 aagagttgat ttcccaatcc caggatcccc accgatgagg acgagacttc ctggtaccac
     3841 tccgcctcca agcacacggt tgaattcctc catctccgtc ttggttcgat tgacattgat
     3901 ggaagtcacc tcagctagtt tcatgggctt ggttttctca cctgtcaagg acacacgcgc
     3961 attcttgacc tcggcaacct caacctcttc cacaaaagaa gaccaagacc cacagttggg
     4021 gcaacgtccc agatatttag gggaattata cccacaattt tgacatacaa atgtcgcttt
     4081 tttctttgcg atgacaaacc tctttctata tctctaactc acactcaatc acttggcaaa
     4141 aatcaatctt ctcatttggc acaaactggc gcatgagcat tcgatgagca acaactacca
     4201 cagtctgatg ttctcgatac ttagacatac attctagaaa ccgagacttc atttccgtag
     4261 ctgtctcata ttgaatagga ctattaggaa gcaactcccc cttgttttct aaaaacagtc
     4321 ttctagctgt ttcaaagttt tctattcctg ttttatagac ctgccattca tgtaataaag
     4381 gctctactct taaaggaaga ctcgtagcac agaccacata cgaagccgtt tctaaagctc
     4441 ttgtgactgc agaagatacg attatttcag ctgacgagag taaaggattt ttgctcaatt
     4501 tctggacttg ctgccgtccc atctcagaca agggtgccaa atctatccca aatcctatat
     4561 aagaacgctc ctctaactca cggtaatctg gctccccatg acgtacaaag ataatcttca
     4621 ttctagtgcc ctgtcgatcc aaatccacca gttcgaacgc catcagctgc atctccatct
     4681 gcaattaaga aagtagcaaa aacagcctgg acaatacgtt ccccaacttc aagaacaacc
     4741 tcttggtctg tgatattctt catctgcgca aaaatatgcc cttcatttcc aggatttcca
     4801 taataatccc catcaatgac cccaactgag ttaattaaaa ccaagccctt cttacgagga
     4861 tttgaagaac gatcatagag gtagagaacc tcagtcggct gcatataagc cttaacccct
     4921 gtcggaacca agacaatctc tcctggcgca acaactgtac gcacagcaac ctttaagtcg
     4981 taaccagccg catgcgctgt ctcacgcttg ggcaataaat tttcatctgt aaaactcgaa
     5041 accaattcaa aaccacgaat tttcataatt ttctcttttc tattatcatt tattctagat
     5101 tattctatct tatttattcg gaaaaagcac aaaaaaagag cacacaattc aaatcgctta
     5161 gggctgctgg attcctcccc tgacccgctt cacgcagaac tgttgctcca ctatttatta
     5221 tatcacattc ctattcattt taaaagcaaa attatttttt ccgtctattt ctaaaaaaat
     5281 cctgcatgat agctgcgcat tcatcttcca aaattcctat ttcaacctcc acacgatgat
     5341 tgagacgctc atctgtcaag atatcgtaca aactcccagc agcgccaaat ttctggtttt
     5401 tagccccata gaccacattt ggaatgcggg caagcccaat cgccccacta cacatgacac
     5461 aaggttcaat ggtcacaaaa agtgtgcaat ccagcaagcg ccagctctcc tcactcaagt
     5521 tcgcatcctc tatagccata atttccgcat gcataaccgc tcgctgtaat tcctcacgcg
     5581 cattatgccc acgaccaatg atttccccat ctttgacaat cacacaacca attggaattt
     5641 catcgtgttc aagagcaatc tcagcctctc tcaaagcctc cctcataaag acttcttttt
     5701 cttcaagcgt ataatacatc tcttttctct tttcctactt atcgatttta ttattatatc
     5761 atgaatccca acacaaaaga agccaccgaa tgcggtgact ctatagggag attattatga
     5821 aaaagaaaag tttaggatat ttgttacaac aagttaggag gtcttcttgt aaccgtttat
     5881 agtatacccg acctatctta aacaaatctt aaaaatctct taggaccaaa cactttctaa
     5941 aatatttgtt tgttcacgac caggacctac tgagaaagta gaaatacgaa cgccaaccaa
     6001 ttcactcaca cgacgaacat agttacgcgc attctcagga agatcttcca aattgcgaac
     6061 tccggtaata tcttctgacc aacctggcaa ctcttcatag ataggcttgc aacgtttcaa
     6121 ttgctcaaga ctagctggat agtagtcaat acgttgaccg tcaagatcat aggccacaca
     6181 gattttcaca gtatccaaac cgctcaaaac atcaatagag ttcaaagaaa ggttagtaat
     6241 accagaaaca cgacggctat gacgcatcac aactgagtca aaccaaccta cacgacgtgg
     6301 acgaccagtt gttgtaccat actcatgacc cacttcacgg atacgttctc ccacttcatc
     6361 aaacaactca gttgggaaag gaccatctcc tacacgactc gtataagctt tacatacacc
     6421 tacaaccttg tcaatcttgc ttggaccgac accagaacca attgtcacac caccagctac
     6481 agggtttgat gacgtaacaa atggataagt accttggtcg atatctagca taacaccttg
     6541 tgcaccttca aaaagcacac gtttgccatt atcaagcgca tcattcaaga taacagatgt
     6601 atctatcacg tatttcttga tttgttgacc atattcgtaa tattcttcaa aaatatcatc
     6661 gaaaacaatc gctttactgt catacaattt ttcaaaaaga cgattctttt cagcaaggtt
     6721 acgttctaaa cgctcacgga aaatatcttt atctaaaaga tctgcaatac gaattccaac
     6781 acgagcagcc ttgtccatat aagctggacc aattccctta attgtcgtac caatcttatt
     6841 gtcgccctta gcttcttctt gcaagcgatc caactcgata tgataaggca aaataacatg
     6901 cgcacgatca gaaatacgca agttatcagt tgttacacct tcctcatgaa gatagctcaa
     6961 ctcttttaca agagatttag gatttacaac cataccattc ccaatgacag atattttttc
     7021 agggaagaaa atcccagatg ggatcaagtg caacttaaat ttcttaccgt caatcacaat
     7081 cgtgtgacca gcattatcac caccttggta acgtgcaatc acttctgcat tcgctgaaag
     7141 gaagtctgta atcttccctt taccttcatc accccattgg gtacctacaa caacaactga
     7201 agtcataatc ttgtctgagc cctcaggctc ttcctttctc acatacatgg caggactctc
     7261 acctgcaatt atatcttaca atttattata ataaaaaatc gcctttttat caagaagaaa
     7321 caatagaaag atttgctatt tccaactatt aaaaaatgat ttagaaaaat tactagctat
     7381 ttactatcat ctttccataa aagagtaaat tagttcggaa atttactaaa attacctcaa
     7441 caagaaataa aaccccgatt cattaccaat ttttcaagat acaaacgata agcaacacga
     7501 taatggtaaa caataaaatc cttacgacaa ccaatgccat atcttactaa ataataaatt
     7561 aaaaatttaa aatgaacatg ttcccagtca aaattatcac caaatgtagg accatactct
     7621 tcttcaatac tatcatagaa attagccatc tgctcataaa ttttttgtaa cataatcaaa
     7681 tactcctttt cttttttata aacttattct aacaaaaaat tttacacatt cactatcaat
     7741 tcctgaattg ttaaaatacc agcctcaaca agataaaaat aggaaaagtt gacaaaatag
     7801 aaacaaattt gctacctaaa tttcaaacaa ttaaagttct aaaaagaccg ccttaaaact
     7861 tttgggtaaa tcctattaaa actataatat ttttatatag gtattatggt tctgattttc
     7921 tagtataaaa aaattcaaac tagaattctc cttagaaagc gtcgattcaa gtgctatcac
     7981 tgttcaaaaa tgatggtcgc tgaaacttct atcgtcaaga agaatcatca aattccttgt
     8041 atcatcaacc aaaagattgc tcagaagcta attgaaaaga cttctatgac cgacattgat
     8101 tatcagttgt ctatttcaac tgtcattcgc aagatcaatg attttcactt tgagcatgat
     8161 ttttcgcgtc ttcctgagat tatgtcctag gacgttgaaa cagtccaggg agtgactatt
     8221 tcaatcggga gatggagatg agctttattg ctcaggactt tgataagctc aatatcataa
     8281 ctgttcttga gagcagaaca caagccatca tacgaaatcc catgaataca aggctatcaa
     8341 gcgctactgg agctcattca acaagatagt cagaaactga gtgataaacg attttatcgc
     8401 cctacttttc gtatgcactt gactaataaa gaaattctag ataaactttt gagctattcg
     8461 aagacttgaa acaccactat aatctctatc agctataatc tctatcagct cttgcttttc
     8521 cacctctttt tcagactctg tttaaaacct tcctcaaaga taaagaaaaa atcgtcaacg
     8581 gccttcaatt accttattcc aacgccaaac tggaagccac caataatctc atcaaactta
     8641 tcaagcacaa tgcctttggt tttaggaact ttgaaaactt caaaaaagaa aggacgaaat
     8701 ttgtcctttc tcaagcttag cttttcttca acccactaca gttgacaaag agccactatt
     8761 tttggttcat tttactataa cacgaaatag attattatta cataataaaa aagaggtcta
     8821 aacctcttaa ctaaattact ccgccagtag gactcgaacc tacgacatca tgattaacag
     8881 tcatgcgcta ctaccaactg agctatggcg gatta
//
LOCUS       DAVAGB010000064         8621 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVAGB010000064 DAVAGB010000000
VERSION     DAVAGB010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8621
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.065"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            472..1305
                     /locus_tag="VQO19_001921"
     CDS             472..1305
                     /locus_tag="VQO19_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase family
                     protein"
                     /protein_id="HET1350135.1"
                     /translation="MNPLKECYEKNGILIAAHRGTNGGNILQNTSKAYLNSIRHNADM
                     FEVDVIRSKDGEFFAFHDGQEPLVFGEKIDIRTLSSEEIQRKECFNSLNEPILQKIEK
                     ISDVLKNFEGQSLINIDRSWFYWDTFLDKLKTYPSLNQVLLKSPVKKELLEMLRDSGL
                     NIMYMPIIKTIEELDFVLSFEGINIVAVELVFQDLENPIISKKVIDDLHEKGLLIWVN
                     ALTLSDSIILSAKIDDDTAIAHDGESWGKLVSIGFDIIQTDWPLLLYQYLVEKNKKIK
                     K"
     gene            1332..2393
                     /locus_tag="VQO19_001922"
     CDS             1332..2393
                     /locus_tag="VQO19_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET1350136.1"
                     /translation="MFKNFKKIAFTSSLILLAACSNNASNTNQSTDEGSVDKSQEIVI
                     YTNSASNGRADWLQTKASEQGYNLRLVDISGGELADRLIAEKNNAVADMVIGLNKLEF
                     NRIKAEKLLVKYSPKWADEVDSSLGDSEGYYSPIVNQPLVLIGNKDAKMPSDWTDFTD
                     SSYKGKYGISKLSTGTSKNIFASIVSRYKDEKGELGISDEGWKVAKAYLKNAHVYAEG
                     EDYISSIMDNNNELKYSMMWGSGVLQNQKEREYKFQVMSPKVGVPYVTEQVGILNTSK
                     KQALLKEFVDWFGSSELQKEWSDKFGSIPANKKALEQAKDELKQFANSVKPQELDWEF
                     IGKNIDSWIEKAQLEFVEQ"
     gene            2410..3414
                     /locus_tag="VQO19_001923"
     CDS             2410..3414
                     /locus_tag="VQO19_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1350137.1"
                     /translation="MITFKDIQIKYNDFIAIDNLNLTINEGEFFTFLGPSGCGKSTTL
                     RALVGFLEPSQGQILVDNQDITNLDPEKREIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VSPEIIKAKVHEIAKKINISDEQLNRNISELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVSLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGFIEQVGTPY
                     DIYNQSETQFVCDFIGSINKISQEVLKKLQGENKYFKETEGYIRLERVKLEKTSPQDL
                     SITGVISDIEFNGVLIKYKVDLSNSESIHIIEKNDGLSRHIIEEKVTMYINPRDIMQF
                     "
     gene            3426..5120
                     /locus_tag="VQO19_001924"
     CDS             3426..5120
                     /locus_tag="VQO19_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET1350138.1"
                     /translation="MRKSLNWKDWLIRLGVLWLIFALIIYPNIELLSGVFYKNGSFTL
                     EAFNKIIHSQRAMSSIFNSFILAISMVFTVNIVGTLIVLLTEYWDIRGSKILKLGYMS
                     SLVYGGIVLATGYKFVYGANGLVTKTLSSIIPGLAPNWFQGFGAVLFIMTFACTSNHI
                     MFLTNAVRSVDYHTIEAAKNMGASPLKVFFSVVFPTFKPTLFALTILTFLTGLSAVSA
                     PLIVGGKDFQTINPLIISFAKTTSSRDLAALLAIMLGLATILLLTLLNHVEKGGNYVS
                     VSKTKASIKKQIISSPLWNTLAHIVAYVLFAIYMLPIVLIILYSFTDSLTIKTGTLDL
                     SKFTLANYANLFTDAQSFRPYLVSVVYAILAAVIATIIAIVISRIVHKNKSKFDKFFE
                     YGALIPWILPGTLIALGLMFTYNIPHLILFNLVLVGTVIILLIAYTIQKLPFSYRMIR
                     AVFFSIDNDMEEAARSMGASSFYTMVRVIIPYILPVVLSVVVLNFNSLLSDYDLSVFL
                     YHPLFQPLGIVIKQSTDETATLNAQAMMFVYSVILMIMSSAALYLSSLFQGKRGKR"
     gene            5122..5823
                     /locus_tag="VQO19_001925"
     CDS             5122..5823
                     /locus_tag="VQO19_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HET1350139.1"
                     /translation="MNLSYELSIWEILLRCFLAILFGGIVGYERGVKNQAAGIRTYLL
                     VCLGTCVVMMTNQFITSRYGSGDPSRMGAQVISGLGFLGAGTIMVTNQKVKGLTTAAG
                     LWSSATIGLAIGIGFYEGAILAGVVLIAVLTLFTPLKDYLNSKTKIADYYLVFSSLEG
                     YNRLLIYLNTSGIKILEIQNGIGNLDEERQLNKIKSTKVSCYLSLKLNENFEHLKLME
                     EMHNIAGVIYVEEIR"
     gene            5870..6469
                     /locus_tag="VQO19_001926"
     CDS             5870..6469
                     /locus_tag="VQO19_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HET1350140.1"
                     /translation="MNIIFDLGNVLIEWNKEKILSKICKNDLEYNLFNKLVFQSNLWI
                     DLDNGKISLEFLENQLIDEMGHQYQDQIHELVWNWFNYVDLYDEVYELIKQLKKKNFQ
                     IYVLSNTSSIFHILLDSVLSKVSSVLDGYVISCEVKMMKPQKEIYLSLVNKYQLDIKD
                     CIFLDDLEENVEAARTLGIKAFQIKERKEISNILKDLLN"
     gene            6479..8506
                     /locus_tag="VQO19_001927"
     CDS             6479..8506
                     /locus_tag="VQO19_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET1350141.1"
                     /translation="MVTIKDIARVSGVSHGTVSNVLNKKGNVSAAKIKLVEETAKKLG
                     YNMNSQAQFLRKGASSKCFFLLFNNARKKYAEYFAEIDQLSLDVEYVYLHKFSEIKNK
                     ISAILSENPQFIVCLGFSPKRFVDIEDNIPIFEVDTYQSNKTLSSFDSDKIFEIVLEL
                     VRTEKLSNLYFISLTNEKEHSLFEYLTQKIKNSTHIQVQERLQLLSLYPTLKNFAKYD
                     CIFVDDEDLMHTLLDLFDWFTIIDRPKICLIGSRVWFEKRNLFYIHLDYRILALNTAE
                     NLESGNSSIVPVKDGKQILIDQLFDGECDDIYLLTVHSPMNKALEILSEKYKQISGKN
                     IKIIEKRYDELLEMIESGDVSSSFDMIRMDMAWLPTFGKKYFQEITSFRQTKSINQNI
                     SKSVSREYMYIDQKQYTFPLDVSSQILVYRKDLFEDSFLQRRYFEKTKRKLTVPKSYQ
                     EFDELSEFFTLTENPFSPTLYGHSLALSSSVRAACEFIPRFRERLAQSRMNLAVLPQV
                     LTEYEKSYQFTEKSFNSSWNDFVTNLNSGKTSMEIIFSNYTSPLFDGLNVSAQFEFAT
                     ATIPGNTPVIGGGSIGISKYSNRVEECLNFINWLYSEEISILLTSLGGFLPSKYVMQN
                     RMLQFQYPWLSSLEDTFSIGSRTKWYGFNTDFRFEQMLGQELIESVKHRYG"
BASE COUNT         3068 a         1104 c         1491 g         2958 t
ORIGIN      
        1 caggaagtct attttaaaaa ttgaagaaat taaaaagaga tgatattagg gagaactgat
       61 ttaaaagttc tccctattta acattattaa ataaaaccta attatatagt aaactgaaat
      121 aagatataaa caaatgaatt ggagcttaac atccatttcc agctaatttt ttagaaacta
      181 cagtgtacta ctctggattc aacacattat aattgaaatt gaaggttaga tttaaagtaa
      241 taaagaataa tattatgctc taaaattaga taaatttcaa ataattaagg atacctatca
      301 ctattataaa gtaactgaac aacattttat atttaataat tatttaaaat aataaaatta
      361 taacattata taaattattt taaaaaataa tgaaacgttc caacttatct attgacacgt
      421 tccaagaaat cggatacaat gtaattaaca ataaagatag gagaaaataa tttgaatcca
      481 ttaaaagaat gctatgaaaa aaacggtata ctaattgcag cacaccgtgg tacaaacgga
      541 ggaaatatat tacaaaacac atcaaaagcc tatttgaatt ccatacgcca taacgcagat
      601 atgtttgagg ttgatgtaat tcgttcaaaa gatggagaat tttttgcatt tcacgatggg
      661 caagaacctt tagtatttgg tgaaaaaatt gatattagaa ctttgagttc tgaagagatc
      721 caaagaaagg aatgttttaa ttcactgaat gaacccatat tacaaaagat tgaaaaaatt
      781 tctgatgtat taaaaaattt tgagggacag tctttaataa atatagatag aagttggttt
      841 tactgggata ccttcctaga taagttaaaa acatatccat ctttgaatca agttctttta
      901 aaatcacctg taaaaaaaga attattggaa atgcttagag actctggttt gaatattatg
      961 tatatgccaa ttatcaaaac aattgaagag ttagattttg ttctctcatt tgaaggaata
     1021 aatatagtag ctgtcgaact tgtattccaa gatttagaaa atccaatcat aagtaagaaa
     1081 gtaattgatg atttacatga aaaaggatta cttatttggg ttaatgcttt aaccttaagt
     1141 gattcaatta ttctttcggc taagattgat gatgatacag ctattgctca tgatggcgaa
     1201 tcttggggga aattggtttc aataggattt gatattattc aaacagattg gccattatta
     1261 ctttatcaat atctagttga aaaaaataaa aaaataaaaa aataaaaaaa taaaaataaa
     1321 ggagaactat catgttcaaa aactttaaaa agattgcatt cacttcttca ctaattttac
     1381 ttgctgcttg ctcaaacaat gcttcaaata caaatcagtc tactgatgaa ggaagtgttg
     1441 ataaatctca agaaattgta atctatacaa attcggcttc taatggacgt gcagattggt
     1501 tacaaaccaa agcatcagag caaggataca atcttcgttt ggtagatatt tcaggtggag
     1561 aactagctga ccgtttgatt gcagaaaaga ataatgctgt ggctgatatg gtaattggat
     1621 taaataaatt agaatttaac cgtattaaag ctgaaaaact tcttgtaaaa tactcaccaa
     1681 aatgggctga tgaagtagat agctctttgg gagattctga agggtattat tcaccaattg
     1741 taaatcaacc attagttttg attggtaata aagatgctaa aatgccatcc gactggacag
     1801 attttactga ttcatcttat aaaggtaaat atggtatttc aaaattaagt acaggtacat
     1861 ctaagaacat ctttgcaagt attgtttcga gatataaaga tgaaaaaggt gagttaggaa
     1921 tatctgatga aggttggaaa gttgcaaaag cttaccttaa aaatgcacac gtttatgcag
     1981 aaggtgaaga ctatatctct tcaattatgg ataataataa tgagctaaaa tatagtatga
     2041 tgtggggatc tggtgttcta caaaatcaaa aagaacgtga atataaattc caagtaatgt
     2101 caccaaaagt tggtgttcct tatgtaactg aacaagttgg gattttaaat acaagtaaga
     2161 agcaagcatt attaaaagaa tttgtagatt ggtttggctc ttcagaactt caaaaagaat
     2221 ggtctgataa atttggttca attccagcta ataaaaaagc tctagagcaa gcaaaagatg
     2281 aactcaaaca gtttgctaat agtgttaaac cacaagaact tgactgggag tttatcggaa
     2341 aaaacatcga ttcttggatt gaaaaagcac agcttgaatt tgttgaacag taatagttag
     2401 gattaagtga tgattacatt taaggatatt caaattaagt ataatgattt tattgccatc
     2461 gataatctca atttaacaat caatgaagga gagtttttca catttttagg accaagtggt
     2521 tgtgggaaat caacaactct tcgtgcacta gttggatttt tggagccttc acaggggcaa
     2581 atactagttg ataatcaaga tattacgaat ttagatccgg aaaaacgcga aattggtatt
     2641 gtgtttcaaa gttatgcatt attcccaaca atgactgttt ttgataatat tgcttttggt
     2701 ctaaaagtta aaaaagtttc tcctgaaatt attaaagcta aagttcatga aattgcgaaa
     2761 aaaattaata tctcagacga gcaactaaac cgaaatattt ctgaattatc agggggacaa
     2821 caacagcgtg tagctttagc acgtgcatta gtattagaac caaaaattct ttgtttggat
     2881 gaaccgttat caaacctaga tgccaaacta cgagtttcgt tgagaaaaga attgaaacga
     2941 ttgcaaaaag aactaggaat cactactctt tatgtcacac atgatcaaga agaagcatta
     3001 acattatcag ataggattgc tgtgtttaat aatggattta ttgagcaagt tggcacgccg
     3061 tatgatattt ataatcaatc cgaaactcaa tttgtctgtg attttattgg ctcaatcaat
     3121 aaaattagcc aagaagttct taaaaaatta caaggcgaga ataaatactt taaagaaact
     3181 gaaggataca tacgcttaga gcgtgttaag ttagagaaaa cttcacctca agatttatct
     3241 ataacaggag taattagtga tattgagttt aatggtgtac ttattaagta taaagtagac
     3301 ttgtcgaata gtgaaagtat tcatattatc gaaaagaatg atggactatc acgtcatata
     3361 atcgaagaaa aagtcactat gtacattaat ccgcgtgata taatgcaatt ttaaggagat
     3421 tgtgcatgag aaagagtcta aactggaaag attggctcat aagattagga gttttatggc
     3481 taatctttgc cctgattatt tatccaaata ttgaactttt gtctggagtg ttttataaaa
     3541 atggttcatt tactctagag gcattcaata agattataca ctctcagaga gcgatgagta
     3601 gtatatttaa tagctttatt ttggcgattt caatggtctt tactgtaaat attgttggga
     3661 cattgattgt tctactcaca gagtactggg atattagggg ttcaaaaata cttaaattag
     3721 gttatatgag ctctctagta tatggaggaa ttgtattagc gacaggatat aaatttgttt
     3781 atggcgctaa tggtcttgta actaaaacgc tctcaagtat aattccaggt cttgccccta
     3841 actggtttca aggatttggt gcagtattgt ttattatgac atttgcttgt acctcaaatc
     3901 acataatgtt tttaacaaat gcagttcgta gtgttgatta tcatacaatt gaagcagcta
     3961 aaaatatggg tgcaagtcct ttaaaagttt tctttagtgt ggtttttcca acttttaaac
     4021 ctacgttatt tgccttaacc atcttaactt ttttgacagg tctttcagca gtttctgctc
     4081 ctttgatagt aggggggaaa gattttcaaa ctattaaccc attgattatc agtttcgcta
     4141 aaactacaag ttcgagagat ttagcagctt tactagctat catgttaggt ttagcaacta
     4201 ttctattatt gacacttttg aatcatgtcg aaaaaggagg taattatgta tctgtttcga
     4261 aaaccaaggc tagtattaag aagcagataa tttcttctcc attatggaat actcttgctc
     4321 acattgttgc gtatgtattg tttgcaatct atatgttacc aatagttttg ataattctat
     4381 actcgtttac agactcgttg acgatcaaga cgggaacttt agatctatct aaatttacgt
     4441 tagcgaacta tgctaattta tttacagatg ctcaatcatt tcgtccttac ctagtcagcg
     4501 ttgtttatgc aattttagct gcggtaattg ctacaattat agcaatagta atttcacgta
     4561 ttgtacataa aaacaagagt aagttcgata aattctttga gtatggtgca ctaataccat
     4621 ggatattgcc aggtacattg attgcactag gattaatgtt cacttataat atacctcatt
     4681 taatactatt taatttagtt ttagtaggaa cagtaattat tttacttatt gcatatacta
     4741 ttcaaaaatt accattttct tatagaatga ttcgggctgt atttttcagt atagataatg
     4801 atatggaaga agcagcacgt agtatgggtg catctagttt ctacactatg gtgcgagtta
     4861 ttataccgta tattttacca gtcgtattat cagtagttgt gttaaacttt aattctttat
     4921 tatctgacta tgacttatct gtattcttgt accatccact tttccaacca ttgggaatcg
     4981 ttattaaaca gtctactgat gaaacagcaa ctttaaatgc acaggcaatg atgtttgttt
     5041 attctgtaat tttaatgatt atgtctagtg cagctcttta tttatcaagc ctattccaag
     5101 gtaaacgagg taagagataa tatgaatctt tcatacgaac tgagtatttg ggaaatactt
     5161 cttaggtgct ttttagcgat tcttttcggt ggcattgttg gctatgagcg aggagtcaaa
     5221 aaccaagcag cagggattag aacctactta ctagtttgtt tgggaacttg tgttgtaatg
     5281 atgacaaatc agttcatcac tagtcgttat ggtagcggtg atcctagtcg aatgggagcc
     5341 caagtaatta gtggcttggg tttcctaggg gcaggaacaa tcatggtaac taatcaaaaa
     5401 gttaaaggtt taacaacagc agctggatta tggtcttcag caactattgg tttagctata
     5461 ggcattggtt tttatgaagg tgctatttta gccggagttg tactcatagc agttttaact
     5521 ctatttactc ctcttaaaga ttatttaaac tcgaaaacta aaattgctga ttactacttg
     5581 gtttttagtt ctttagaagg ttataatcgt ttacttatat atttaaatac atcgggtatt
     5641 aagattttag aaattcaaaa tggtatagga aatcttgatg aagaacgtca attaaataaa
     5701 attaagtcaa caaaagtgtc ctgctattta tcattaaaat taaacgaaaa ctttgaacat
     5761 ttaaaattaa tggaagaaat gcataatatt gctggtgtta tttatgttga agagattagg
     5821 taagggtgac tttgtctaat tttttctata tttctaatcg gagaaaaaaa tgaatataat
     5881 ttttgattta gggaatgtgt tgattgaatg gaataaagaa aaaattttat caaaaatctg
     5941 taagaatgat ttagaatata atttatttaa taagttggta tttcaatcta acttgtggat
     6001 tgatttggat aatggtaaaa ttagtttaga gttcttagag aatcaattaa tcgatgaaat
     6061 gggacatcaa tatcaggatc aaattcatga gttagtatgg aattggttta actatgttga
     6121 tttatatgat gaagtttatg aattaataaa acagctaaag aaaaagaatt ttcaaattta
     6181 tgttttatca aatacctcct caatttttca tattttatta gattctgttc tatctaaagt
     6241 atcatctgtt ttagatggtt acgtaatttc ttgtgaagtt aaaatgatga aaccacaaaa
     6301 agaaatttac ttgtcattag ttaataaata tcaattagat ataaaagatt gtatattttt
     6361 agatgattta gaagaaaatg tagaagctgc aagaactcta ggtattaaag catttcaaat
     6421 taaagagcgt aaagagatct caaatatact aaaagatctc ttaaactaga ggttaattat
     6481 ggttacaata aaagatattg caagagtgtc tggagtctca catgggacag tttcaaacgt
     6541 tttaaataaa aaaggtaatg tctcagcagc taaaataaag ttagtagaag agactgcgaa
     6601 aaaattgggt tataatatga attctcaagc tcagtttctt cgaaaaggcg cttctagtaa
     6661 atgttttttc ttgttattta ataatgcacg caaaaagtat gctgagtatt ttgcagaaat
     6721 tgatcagtta tctttagatg tagaatatgt ttacttacat aaattctcag agattaaaaa
     6781 taagatatct gcaattttaa gtgaaaatcc tcaatttata gtttgcttag gtttttctcc
     6841 aaaaagattc gttgatattg aagataatat tccgattttt gaagtagata catatcaatc
     6901 taataaaact ttatcttcct ttgatagtga taaaatattt gagattgtac ttgagttggt
     6961 tcggactgaa aagctatcta atttatattt tatttcactt actaatgaaa aagaacattc
     7021 tttatttgaa tatttaactc aaaaaataaa aaactcaact catatacaag tgcaagaacg
     7081 tttacaattg ttgtctctat atcctactct aaaaaacttt gcaaagtatg attgtatatt
     7141 tgttgatgat gaagatttga tgcacacgct attagactta tttgattggt ttactataat
     7201 tgatagacca aaaatatgtt tgataggttc acgtgtttgg ttcgaaaaaa gaaatctttt
     7261 ttatatacat ttagattata gaatattggc actcaatact gccgaaaatt tagaaagtgg
     7321 aaatagttca attgtaccag ttaaagatgg caaacaaatt ttaattgatc aattatttga
     7381 tggagaatgt gatgatattt atttacttac tgtccattca ccaatgaata aagccttaga
     7441 aattttatca gaaaagtata aacaaatttc tgggaaaaat attaaaatta tcgagaaaag
     7501 atatgatgaa cttttggaga tgattgagtc tggcgatgtt tcatccagtt ttgatatgat
     7561 tagaatggat atggcttggc ttccaacatt tgggaaaaag tattttcaag agattacaag
     7621 ctttagacaa acaaaaagta ttaatcaaaa tatttctaag tcggtgtctc gagaatatat
     7681 gtatattgat cagaagcagt atacttttcc attggatgtt agtagtcaga ttttagtata
     7741 tagaaaagac ttatttgaag attcattttt acaaagacga tactttgaaa aaacaaaaag
     7801 aaaattaact gtaccaaaaa gttatcaaga gtttgatgag ttaagtgaat tttttacatt
     7861 aacagaaaat ccattttcac ctacacttta tggccatagt ttagctttaa gttcttcagt
     7921 gagagcagca tgtgaattta ttcctcggtt tcgtgagaga ttagcacaat ctagaatgaa
     7981 tcttgctgta cttcctcagg ttttaactga gtatgagaaa agttatcagt ttaccgaaaa
     8041 atcatttaat tcttcgtgga acgatttcgt tacgaactta aacagtggta aaacttcaat
     8101 ggaaataatt ttttcaaatt atactagtcc attatttgat ggtctcaatg tttctgctca
     8161 gtttgagttt gcaactgcca ctatacctgg taatactcct gtgataggtg gtggctcaat
     8221 tggaatttct aaatattcaa atagagtgga agaatgtcta aactttatta attggttata
     8281 ttctgaagag atttctattt tactaacatc tctgggtggt tttttaccat caaagtatgt
     8341 catgcaaaat aggatgttac aatttcaata cccatggtta tctagtttag aagatacatt
     8401 tagtattggg agtagaacaa aatggtacgg ctttaatact gattttagat ttgagcagat
     8461 gttagggcaa gagttaatag aaagtgtgaa gcatagatat ggataaatta atactaaatt
     8521 tttattacta gtttatttat tattgtttaa aattaaagat tcaagtaaac accaattata
     8581 tttaaaatta ttattttgac atttttctat tgcaaagtta t
//
LOCUS       DAVAGB010000065         8557 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVAGB010000065 DAVAGB010000000
VERSION     DAVAGB010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8557
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.066"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            153..1172
                     /gene="galE"
                     /locus_tag="VQO19_001928"
     CDS             153..1172
                     /gene="galE"
                     /locus_tag="VQO19_001928"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET1350142.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGIIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLKIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            1174..2127
                     /locus_tag="VQO19_001929"
     CDS             1174..2127
                     /locus_tag="VQO19_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET1350143.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(2189..2395)
                     /locus_tag="VQO19_001930"
     CDS             complement(2189..2395)
                     /locus_tag="VQO19_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HET1350144.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            2447..2923
                     /locus_tag="VQO19_001931"
     CDS             2447..2923
                     /locus_tag="VQO19_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HET1350145.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            2932..3603
                     /locus_tag="VQO19_001932"
     CDS             2932..3603
                     /locus_tag="VQO19_001932"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HET1350146.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYIDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            3734..4072
                     /locus_tag="VQO19_001933"
     CDS             3734..4072
                     /locus_tag="VQO19_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HET1350147.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            4075..4704
                     /locus_tag="VQO19_001934"
     CDS             4075..4704
                     /locus_tag="VQO19_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HET1350148.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            4944..6095
                     /locus_tag="VQO19_001935"
     CDS             4944..6095
                     /locus_tag="VQO19_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET1350149.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            6413..7162
                     /gene="truA"
                     /locus_tag="VQO19_001936"
     CDS             6413..7162
                     /gene="truA"
                     /locus_tag="VQO19_001936"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HET1350150.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVAADFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            7152..7925
                     /locus_tag="VQO19_001937"
     CDS             7152..7925
                     /locus_tag="VQO19_001937"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET1350151.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            7903..8364
                     /locus_tag="VQO19_001938"
     CDS             7903..8364
                     /locus_tag="VQO19_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET1350152.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNDWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT         2402 a         1613 c         1922 g         2620 t
ORIGIN      
        1 atggcaaggc gacgttgacg tggtttgaat tggattttcg aagagtataa gcattttact
       61 gaaattttat caggtagttt aggatggcaa atgacattcc ctgtcaaaaa tggtaaaata
      121 agaaaaaata atctgagaat cgaggaaaaa agatgcaaga aaagattttg gtaactggtg
      181 gtgccggttt tattggaacc cacactgtta ttgaattgat ccaagcaggc catcaagttg
      241 ttgtggtgga taatcttgtc aatagcaatc gtaagagttt agaagttgtt gaaagaatca
      301 caggagttga gattcctttc tatgaggcag atattcgtga cacagatacc ctcagagata
      361 ttttcaagca ggaagaaccg actggtatca ttcactttgc tggtttgaag gctgttggcg
      421 aatcaacacg tatccctctt gcctactatg acaacaatat cgctggaact gtcagccttt
      481 tgaaagccat ggaagaaaac aactgtaaaa acatcatctt cagttcttct gcgacagttt
      541 acggggatcc gcacacagtg cccatcttgg aagatttccc actttcagtg accaacccat
      601 acggtcgtac caagctcatg ctagaggaaa ttttgaccga tatttacaaa gcagactcag
      661 aatggaatgt tgtcttgctt cgttacttta acccaatcgg agcccatgag agtggtgatt
      721 tgggagaaaa tccaaacggt attccaaaca atctcttgcc atatgtgact caagtagccg
      781 ttggaaaatt agagcaagtg caagtgtttg gagacgatta cgatacggaa gatggaacag
      841 gtgttcgtga ctatatccac gttgtcgatt tggctaaggg tcacgttgca gctttgaaaa
      901 aaatccaaaa aggttcagga ctaaacgttt ataaccttgg aactggtaaa ggttactcag
      961 ttcttaaaat tatccaaaac atggaaaaag cggtgggacg tcctattcct taccgcatcg
     1021 tagaacgtcg cccaggtgat atcgctgcct gctactcaga cccagcaaaa gctaaagcag
     1081 aactcggttg ggaagcagaa ctcgacatca cccaaatgtg tgaagacgca tggcgttggc
     1141 aaagcaagca tccaaatgga tttgaagact aagatgatga tttcaatcat cgtcccttgt
     1201 ttaaacgaag aggaagtact tcctcttttt tatcaggctc tggaagcttt acttccagat
     1261 ttggaaacag aaatcgagta tgtctttgtc gatgatggat caagtgatgg gaccttggaa
     1321 ctcttaaagg cctatcggga gcaaaatccg gcagtccatt atatttcttt ctctcgaaat
     1381 tttggcaaag aagcagccct ttatgcaggc ttgcaatatg cgacaggaga tttggtggtg
     1441 gtgatggatg cagacctcca agatcctcct agtatgttgt ttgagatgaa aaatgtacta
     1501 gacaaaaatg tagacttgga ctgcgttggg acacggagaa ctagtcggga gggagaaccc
     1561 ttctttcgca gtttctgtgc tgttctcttt tatcgcctca tgcaaaaaat cagcccagta
     1621 gctctgccgt cgggtgtccg tgattttcgt atgatgagaa ggtctgtggt cgatgccatt
     1681 ttaagcttga ctgagtccaa tcgtttttct aagggactct ttgcctgggt cggctttaaa
     1741 acccactatc tggactatcc aaatgtcgaa aggcaggctg gcaagaccag ttggagtttt
     1801 aggcaactct ttttttactc cattgaaggg attgttaatt tttcagattt ccctttgact
     1861 atagcctttg tagctggtct cctatcttgt tttctttctc tgctgatgac cttttttgtt
     1921 gtggttcgga ccctcatttt gggcaatccg acatctggtt ggacctctct gatggctgtt
     1981 attctctttc ttggaggcat tcaactcttg accattggga ttctcggtaa gtatatcagt
     2041 aagatttatt tagagactaa aaaaagacca ctttatctta tcaaagaaaa aagtgacctt
     2101 cctgatttta cagaaaaaat aaagtgaaaa gactataatt ttacatggaa atgtgctaaa
     2161 ctagagggag tggattatcg ccattgattt aggcttcctg gtttccaatc agggcgcgag
     2221 ttgggcaatt tttaacagcc tctaagacat cctgactagg agaaatttct ttttccagtt
     2281 ggtcagggtc atcgtaaaaa cgcacgattc cattatcgtg gtaatcaaat aaatcagaat
     2341 aagtttggca aagtccacag gcgatacatc gttcaggtat aagtgtgatt ttcatgttca
     2401 tatttatatt gtaataagaa aagtaaaaaa aaacaaggag taaggtatgg caaaagaacc
     2461 gtggcaagaa gatatttatg atcaagaaga atcaagagca gggcgtcggc atcgaaacca
     2521 cggaggggct gataggatgg ctaatcgtat tttgacgatc ctagctagta ttttctttgt
     2581 aattgtggtg gtgatggtca tcgttctcat ctatctatca tcggggggga gcaatcgcac
     2641 agcagcctta aaagactttc atgattctga tgcaagtgta gtacaaatct catcttcaag
     2701 cagttctcag cctgagcaga gttcagagcc agaatctact tctagtagtt cagaagaagc
     2761 tgctaatcct gaaggaacga ttaaagttct cgcaggagaa ggggaagcag ctattgccgc
     2821 tcgtgcagga atctccattg ctcagttaga ggccttgaat cctgggcaca tggctacagg
     2881 atcttggttt gctaatccag gtgatgttat aaaaataaaa taggagccga tatgaaaaca
     2941 attcaaattg ctattgatgg tcctgcttcc agcggtaaga gtacggtcgc aaagattatt
     3001 gctaaggatt ttggattcac ctaccttgat acaggagcta tgtatcgtgc agcgacctat
     3061 atggctctta agaaccaatt aggagttgaa gaagtcgaag cccttctagc cttgttggac
     3121 cagcatccaa tcagctttgg acgttcagaa actggagacc agcttgtttt tgtaggagat
     3181 gtggatatta cccatcctat ccgtgaaaat gaagtgacca atcatgtttc tgctattgca
     3241 gcaattcctg aagtgcgtga gaaactggtt tctctccaac aagaaattgc ccagcaaggc
     3301 gggattgtca tggatggtcg cgatattgga actgttgtat tgccacaagc agaattgaaa
     3361 attttcctag tagcttctgt tgatgagaga gcagagcgtc gttacaagga aaatattgcc
     3421 aagggaattg aaacagacct tgaaacccta aaaaaggaaa ttgctgcgcg tgactacaag
     3481 gatagtcatc gtgagacttc tcctctcaaa caagcagagg atgctgtcta cattgataca
     3541 actggtttga acattcaaga agtagttgaa aaaatcaaag cagaagctga aaaaagaatg
     3601 taaatgtaga aaagccgata gattgatatc ggtttttttc taaatttgtc aaaatgctga
     3661 ttttagggta taatagttgc tgttcgagaa attttgattt tcaaagaata gtgaatgatg
     3721 ataaggagaa accatgaaca atttaccaaa ttgtccaaaa tgtaactcag agtatgtcta
     3781 cgaagacggt gccctactgg tttgcccaga gtgtgctcat gagtggaatc ctgctgaagt
     3841 tgcagaagta gaagaaggtc ttgtcgctat cgatgccaac ggaaataaat tgactgatgg
     3901 tgatacagta actctcatca aggacttgaa agtaaaaggt gcgccaaaag atttgaaaca
     3961 agggacgcgc gtgaaaaata tccgcatcgt agaaggcgat cacaatatcg actgtaagat
     4021 tgatggtttt ggtgccatga aacttaaatc agagtttgtg aggaagattt aagcatgtca
     4081 aaacactata aacttgtatt ttatagccgt atcttcttgt ttctagcggc ttttacggga
     4141 gtttatcttg aaattactag gcatggtggt tttgggatgc ttctctatta cacggttctg
     4201 tccaacctct tggtaactat ttttaccctt tatcttctaa aggttatgag ccgtgtaggt
     4261 gaaaattggc aaaggccaag tctcttgcgc ttaaaaggtg gggtcaccat gagtatcatg
     4321 attacctgtg tgatttacca tttcctcttg gcgcccattg cgactaattt ctatacccta
     4381 gaaaatttcc tttgccacta tatcgttccc atctggtttt tagcggatac cctctttttt
     4441 gacaaacagg gtcaatacaa gatttgggat ccagcagtgt ggaccatttt accctttctg
     4501 tatatgatgt ttgctctttt taatggcttg gttctaaaac tcaatattcc aaatgccaag
     4561 gataatcctt tcccttactt ctttttgaat gtgaacaagg gttggaatgt tgtgtttaag
     4621 tggtgtctga ttatctttgt tgcctatatg gtagcaggat ttattttcta ctttatcaag
     4681 caaatcaaga gaaagtcatc ctaatactct tcgaaaatct cttcaaacca cgtcagtttc
     4741 catctgcaac ctcaaaacac tgttttgaac aacctgcggc tagcttccta gtttgctctt
     4801 tgattttcat tgagtataag atacaaggga ttcattttcg aatttaagaa ggagtctaca
     4861 aaccaatgag gcttcttctt ttcttgctta tttgataact atcaaaaaag tagaagatta
     4921 agagaaatat agaaagagat ttcatgaaac aatttttaga acgggccagc attttggctc
     4981 tctccctcgt tttgattacc tccttttcca tttcgagtgc cctaccagcc atgtttgact
     5041 attatcaggg ttattctaag gaacaaattg agctcttggt gagcttgcct tcctttggaa
     5101 tcatgatgat gttactgcta aatggtttct tagaaaaaat atttcctgag cgcttacaga
     5161 ttagtttggg cttgctgatt ttatcattga gcggtacagc tcccttctgg taccaagcct
     5221 atccctttgt ctttggaaca cggcttctct ttggtttggg tcttgggatg atcaatgcca
     5281 aggccatttc tattatcagt gaacgctacc aaggaaaaag gcgaattcag atgttagggc
     5341 tacgcgcttc tgcagaggtc gttggagctt ctctcattac cttggccgtc ggtcagttgt
     5401 tggcctttgg ttggacagct atctttctag cctatagtgc tggatttttg gtgctgcccc
     5461 tttatctgct ctttgtccct tatggaaaat caaagaaaga agtcaagaaa agagcgaagg
     5521 aagcaagtcg tttaactcga gaaatgaaag gcttgatttt taccttagct atcgaagcgg
     5581 cagttgtagt ttgtaccaat acagctatta ccatccgtat tccaagtttg atggtggaaa
     5641 gaggattggg ggatgcccag ttatctagtt ttgttcttag tatcatgcag ttgatcggga
     5701 ttgtggctgg ggtgagtttt tctttcttga tttctatctt taaagagaaa ctgctcctct
     5761 ggtctggtat tacctttggc ttggggcaaa tcgtgattgc cttgtcttca tccttgtggg
     5821 tggtagtagc aggaagtgtt ctggctggat ttgcctatag tgtagtcttg acgacggtct
     5881 ttcaacttgt ctctgaacga attccagcta aactcctcaa tcaagcaact tcatttgctg
     5941 tattaggctg tagtttcgga gcctttacga ccccattcgt tctaggtgca attggcttac
     6001 taactcacaa tgggatgttg gtctttagta tcttaggagg ttggttgatt gtaatctcta
     6061 tctttgtcat gtacctactt cagaagagag cttaggattg attcctaagt ttttcttttg
     6121 atactcaatg aaaatcaaag agcaaactat agttgattga gtttggaata gtacgctgta
     6181 gctgctaaaa tatttctaga aattaatttg actttcctaa tagagttgtt catatcttat
     6241 ttcaatctac tatagaaagc tagccgcagg ttgctcaaaa tagtgttttg aggttgcaga
     6301 tggaaactga cgtggtttga agagattttc gaagagtatg agatttttat acccatacaa
     6361 tatttgtttt aggtccttgt ttacagacta atttcttgat aaaatagagg ttatgacgag
     6421 atataaagca actatttcct atgatggtta tgcctttgct ggctttcagc gccagcctca
     6481 tgcgcgtagc gttcaggaag aaattgaaaa aaccttgacc agattaaata aagggcaaac
     6541 cattactgtt cacggtgctg gtaggacaga tagtggggtt catgccctgg gacaggtcat
     6601 tcattttgac ctgccttatc agatggatga ggagaaactc cgttttgcct tggataccca
     6661 gtctcctgaa gatattgatg tgatttcgat tgagcttgtg gcagctgatt ttcattgccg
     6721 ttatgccaag catagcaaga cctatgagtt tattgtggat agaggacgtc ccaaaaatcc
     6781 gatgcgccgt cactatgcca cccactttcc ctacccactc gatgtggaac gaatgcagat
     6841 tgcaatcaaa aagctagagg gaacccatga ttttaccggt tttacagcct ctgggactag
     6901 tgtagaggat aaggttcgca ccatcacaga agctagttta atagtcgatg agacaggaca
     6961 atttttgacc tttacctttt ccggaaatgg tttcttgtat aaacagattc gcaatatggt
     7021 ggggactctt ctcaaaatcg gtaacaaccg catgccagta gagcagattg atctcatctt
     7081 ggagaagaag gacaggcaac ttgcaggtcc cactgcagca ccaaatggtt tgtatttaaa
     7141 ggagattcgt tatgaagaat aatcgtattt tagcactttc tggaaatgat atttttagtg
     7201 gtggtggact gtcagctgat ttggctacct ataccttgaa cggcttgcat gggtttgtag
     7261 cagtgacttg tttgacagcc ttgacagaaa aaggatttga agtctttcca actgatgata
     7321 ccatttttca acatgaatta gatagcttgc gtgatgtgga atttggggga attaagattg
     7381 gtcttctccc tactgtcagt gtggctgaga aggccttgga ctttatcaaa caacgcccag
     7441 gagtacctgt ggtgttggat cctgtcttgg tctgcaagga aacgcatgat gtagctgtca
     7501 gtgagctctg ccaagagttg attcgctttt tcccttatgt cagtgtgatt acgcctaatc
     7561 tcccagaagc agaattatta tccggtcagg aaattaaaac cttggaagac atgaaaactg
     7621 cagcgcagaa attgcatgat ttaggagcgc cagcagtcat tatcaaggga ggcaatcgtc
     7681 ttagtcagga caaggctgtg gatgtctttt atgatggaca gacctttact atcctagaaa
     7741 atccagttat ccaaggccaa aatgctggtg caggttgtac ctttgcctct agcattgcca
     7801 gtcacttgat taaaggtgat aaacttttgc cagcagtaga aagctctaag gctttcgttt
     7861 atcgtgctat tgcacaagca gatcagtatg gagtaagaca atatgaagca aacaaaaaca
     7921 actaaaatcg cccttgtatc cctattaacc gccctttctg tggttctagg ttatttctta
     7981 aaaatcccaa cacctacagg aattctaact cttttagatg ctggtgtctt ctttgcggcc
     8041 ttttactttg gtagtcgtga aggagcggta gtcggaggac tagcaagttt cttgattgac
     8101 ctcttatcag gctaccctca gtggatgttc tttagcttgg tcaaccatgg cttgcaggga
     8161 tttttcgcag gatttaaagg aaaaagtcag tggttaggcc ttattttagc aactattgcc
     8221 atggtaggag gctacgcctt gggttctact ttgatgaatg actgggcagc agccctccca
     8281 gaaattctac caaatttcat gcaaaatatg gtagggatga ttgtaggatt tattcttagt
     8341 caaagtatca agaagattaa gtaatactct tcgaaaatct cttcaaacca cgtcagcttg
     8401 tccttagtgt gtatatgtta ctgacttggt cagttctatc cttaacctca aaactatgtt
     8461 tcgaggagcc ttccgctaac ttcccagtct gagtttcatt gaatattaac gatactttat
     8521 cacataaaga ggctggatga aaagtcttca caatcaa
//
LOCUS       DAVAGB010000066         7513 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVAGB010000066 DAVAGB010000000
VERSION     DAVAGB010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7513
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.067"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            <1..185
                     /locus_tag="VQO19_001939"
     CDS             <1..185
                     /locus_tag="VQO19_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET1350153.1"
                     /translation="LIAEDKAYNHALSKERSMVENIFAKVETFKMFSTTYRNHRKCFG
                     LRMNLIAGIINHELGF"
     gene            376..2667
                     /gene="pcrA"
                     /locus_tag="VQO19_001940"
     CDS             376..2667
                     /gene="pcrA"
                     /locus_tag="VQO19_001940"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HET1350154.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVVRT
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNTQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2710..3390
                     /gene="radC"
                     /locus_tag="VQO19_001941"
     CDS             2710..3390
                     /gene="radC"
                     /locus_tag="VQO19_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HET1350155.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3387..4076)
                     /locus_tag="VQO19_001942"
     CDS             complement(3387..4076)
                     /locus_tag="VQO19_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET1350156.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(4094..4735)
                     /locus_tag="VQO19_001943"
     CDS             complement(4094..4735)
                     /locus_tag="VQO19_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HET1350157.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4818..5033)
                     /locus_tag="VQO19_001944"
     CDS             complement(4818..5033)
                     /locus_tag="VQO19_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET1350158.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(5041..5388)
                     /locus_tag="VQO19_001945"
     CDS             complement(5041..5388)
                     /locus_tag="VQO19_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HET1350159.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5393..6508)
                     /locus_tag="VQO19_001946"
     CDS             complement(5393..6508)
                     /locus_tag="VQO19_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET1350160.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6518..7477)
                     /locus_tag="VQO19_001947"
     CDS             complement(6518..7477)
                     /locus_tag="VQO19_001947"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET1350161.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
BASE COUNT         2195 a         1471 c         1622 g         2225 t
ORIGIN      
        1 cgctaatagc tgaagataaa gcctataacc atgcgctatc taaggagaga agcatggttg
       61 agaacatctt tgccaaagta gaaacgttta aaatgttttc aacaacctat cgaaatcatc
      121 gtaaatgctt cggattacga atgaatttga ttgctggtat tatcaatcat gaactaggat
      181 tctagttttg caggaagtct attgaggtat tgagctagtt tatgaaaaaa ttgagtgaaa
      241 agtcgagtgt tttagaaacc cacagtgtag tattctagtt tcaatccact atattttgct
      301 actccccgta aagtttctat tttccctgat ttctgatata atagaaatat tgacttcaag
      361 agtaaggaag agaagatgaa cgcattatta aatggaatga atgaccgtca ggctgaggcg
      421 gtgcaaacga cagaaggtcc cttgctaatc atggcagggg ctggttctgg aaagactcgt
      481 gttttaaccc accgtatcgc ttatttgatt gatgaaaagc tggtcaatcc ttggaatatc
      541 ttggccatta cctttaccaa caaggctgcg cgtgagatga aagagcgtgc ttatagcctc
      601 aatccagcta ctcaggactg tctgattgcg accttccact ccatgtgtgt gcgtattttg
      661 cgtcgcgatg cggaccatat tggctacaat cgtaatttta caattgtgga tcctggtgaa
      721 cagcgaacgc tcatgaaacg tattctcaaa cagttgaact tggatcctaa aaaatggaat
      781 gaacgaacta ttttggggac catttccaat gctaagaatg atttgattga tgatgttgct
      841 tatgctgccc aagctggcga tatgtatacg caaattgtgg cccagtgtta tacaacctat
      901 caaaaagaac ttcgtcagtc tgaatccgtt gactttgatg atttgattat gctgaccttg
      961 cgtctctttg atcaaaatcc tgatgttttg acctactacc agcaaaaatt ccaatacatc
     1021 cacgttgatg agtaccaaga taccaaccac gctcagtacc aattggtcaa actcttggct
     1081 tcccgtttta aaaatatctg tgtggttggg gatgcggacc agtctatcta cggttggcgt
     1141 ggtgctgata tgcagaatat cttggacttt gaaaaggatt accccaaagc caaggttgtt
     1201 ttgttggagg aaaattaccg ctcaaccaaa accattctcc aagcggccaa cgaggttatt
     1261 aaaaataata aaaatcgccg tcctaaaaat ctctggactc aaaacgctga tggggagcaa
     1321 atcgtttact atcgtgccga tgatgagctg gatgaggctg tatttgtagt cagaaccatc
     1381 gatgaactta gtcgcagtca aaacttcctt cataaggatt ttgcagttct ctatcggact
     1441 aatgcccagt cccgtacaat tgaggaagcc ctgctcaagt ctaacattcc ttataccatg
     1501 gttggtggaa ccaaattcta cagccgtaag gaaattcgcg atattattgc ttatctcaac
     1561 cttattgcta atttgagtga caatattagt tttgagcgta ttatcaacga gcctaaacgt
     1621 ggaattggtc taggtacagt tgagaaaatc cgtgattttg caaatttgca aaatatgtct
     1681 atgctggatg cttctgctaa tattatgttg tctggtatca agggtaaggc agcccaatct
     1741 atctgggatt ttgccaatat gatgcttgat ttgcgggagc agctagacca cttaagcatt
     1801 acagagttgg ttgagtccgt cctagaaaaa acaggttatg tcgatattct taacacccaa
     1861 gcgactctag aaagcaaggc aagggttgaa aatatcgaag agtttctttc tgttacgaag
     1921 aactttgatg acaccactga tgtgacagaa gaggaaactg gtctggacaa actgagtcgt
     1981 ttcttaaatg acttggcttt gattgccgac acagattcag gtagtcagga aacatcagaa
     2041 gtgaccttga tgaccctgca tgctgccaaa ggtctcgaat ttccagttgt ctttttgatt
     2101 gggatggaag aaaatgtctt tccacttagt cgtgcgactg aagatccaga tgaattagaa
     2161 gaagagcgcc gtctagccta tgtaggtatc acgcgtgcag agaaaattct ctatctgacc
     2221 aatgccaact cacgcttgct ttttggtcgt accaattata accgtccgac tcgttttatt
     2281 aacgaaatca gttcagactt gcttgagtat caaggtctgg ctcgtcctgc aaatacaagc
     2341 tttaaggcat catatagcag tggtagtatt tcctttggtc aaggtatgag tttggctcag
     2401 gctcttcaag accgtaaacg cggtgctgcc ccaaaatcaa tccagtcaag cggtcttcca
     2461 tttggtcaat ttacagctgg cgcaaaacca gcatctagcg aggcaaattg gtccattggt
     2521 gacattgctc tccacaagaa atggggagag ggaactgttc tggaagtttc aggtagcggt
     2581 gctaggcagg aattgaaaat caatttccca gaagtaggtt tgaaaaaact tttagccagt
     2641 gtggctccaa ttgagaaaaa aatctaattt tccatccttc tcacgaataa taaagtgagg
     2701 aggattttta tgtacagtat ttcattccaa gaagattcac tattaccaag agaaaggctg
     2761 gccaaggaag gagttgaagc gcttagtaac caagagttgc tagctatttt actcaggaca
     2821 ggaacacgtc aagctagcgt ttttgaaatt gcccaaaaag tcttgaacaa tctttcaagc
     2881 ctaacggatt tgaaaaaaat gaccctgcag gaattgcaga gtttgtctgg tattgggcgt
     2941 gttaaggcca tagaattaca agctatgatt gaactggggc atcgtattca caaacacgag
     3001 actcttgaaa tggaaagtat tctcagcagt caaaagttgg ccaagaagat gcagcaggaa
     3061 ttaggggata aaaaacaaga gcacctggtg gcactctatc tcaatactca aaatcaaatc
     3121 atccatcagc agaccatttt tatcggttct gtaactcgta gtatcgctga accgcgagag
     3181 attcttcact atgcaatcaa gcatatggcg acttctctta tcttggtcca caatcatcct
     3241 tcaggagcgg tagcgcctag ccaaaatgat gatcatgtca ctaaacttgt taaagaagcc
     3301 tgcgaactga tggggattgt tctcttggac catttgattg tctctcattc taattacttt
     3361 agttatcgtg aaaagacaga tttaatctaa agttcattaa cgacatagtc aaagagtttt
     3421 ttatctttgg gacgattttc aaaaagaagt tctggatgcc attggacacc gagaaaggcg
     3481 acatcatccg tactcatgac agcctcaatg ataccatctt taggatcatg agccacaact
     3541 tttaaatttg gtgctaagtc cttgatgctc tggtggtgga aggagttgat atgagagatt
     3601 tctccataga tttcttggag aacggtatct ggttctgtta ccaagcgttg agttgtgtac
     3661 tcaacagaag aatcctgcca atggtcttcg atatcttggt acaaagttcc acccatggca
     3721 acgttaaaga gttgggtacc acggcagaca gagaaaatgg gctttttctg tttaatagct
     3781 tccttgatga gggccagttc gaagatatct ctttgaaggt gatagtcatc gctatcaatg
     3841 gttttgggtt cgccatagaa ttttggatcg acattttgcc cacctgtcaa gatgagcttg
     3901 tcaatcaaac tgatatagtg gcaggccatt tcttgatcac caatcggtag gatgatggga
     3961 atccctccag catctttaac gccttcaaca aagccttttg ctgcgtagct catcatgatg
     4021 tcatcatctg gatgagcttt ttcgtttcct gtaatcccaa taactggttt tttcataaaa
     4081 tgattttcgc tttctaatcc tcttttcgca tgaagtagag gagggtttgg agttcacttg
     4141 tcaaatcgac atactgaacg accacgtctt ttggtaaatg cagatggact ggtgaaaaac
     4201 tgagaattcc tttcacacca gcatcaacca agagattagc aacctcttgt gacttgacgc
     4261 tgggaacagt taggatagca gtcttcacat cagcatcctt gattttatcc ttgatctgag
     4321 aaatcccgta aatgggaatc ccgtcaggag tttgggtacc gacttcagga tggtcgtcta
     4381 ggtcaaaggc catgataatc ttcatcttgt tacgttcgtg gaagcggtag tggagaaggg
     4441 catggcccat atttccaata ccaaccagca tgacattggt aatagagttg tcattgagca
     4501 aatcggcaaa aaatgtcatt agttttttga catcatagcc aaaaccacga cgaccaagtt
     4561 caccaaaata ggaaaaatca cgacgtacgg tcgctgaatc aataccgata gcctctgcaa
     4621 tttgcttaga gttggcacgt tcaatctttt ctgcatgaaa tctcttaaaa attcgatagt
     4681 agagagagag tctttttgct gtagcttttg gaatagcaaa ctgtttatct ttcacaaaat
     4741 cacaaccttt ctattcttct attttataga aacattgtga aaaaatcaac aaaaataaga
     4801 aaaaactaag aaaaatctta gttttgatgt aaaaaatctg catgagatag aaaacggtag
     4861 aggtctccga ccagaccctg ataaactttt tggcccctaa aagtcagaga agtcacataa
     4921 agtgtatctg gtaaggttac acatcctgac aaagtcaaca tgagagcctc atgatcctca
     4981 tacttgagag tacgctctac atgatagcag tccttatagg tcagttcaaa cattttggct
     5041 ctatctttcc gattttgtaa agacaccacg ttctaccaag ctatccatga ggaagtagaa
     5101 tttttcctga tgaatatggt ggtcttctga tttgaaaata tcaactagac gaaggccaaa
     5161 cttgtcagtg atattgattt tagcccctgt aagttccttg ttaatgatga ttttgagttg
     5221 gaagccttca ccgctgtttg gcactttttc caaaaggcga gtcagttcat agttaccaac
     5281 cttagtttca aaaaaggtgt tatctttgag ggtgaatttt ttaacagaag ggctaagagt
     5341 gtaatcgtaa cgacaatttt ttaactgaat gattttttca aatgccatat ggctaacctc
     5401 cgataatttc ttttaaggtt tttgcgaggg tttgtaggtc ttcaacggta ttttgtggcg
     5461 acaaactgat gcgaagggat tccttcaagc gttctgaatt tgcgccatac atggcttcaa
     5521 gaacatggct ggattggaca acgcctgcag tacaggctga gccagtagag attgaaattc
     5581 cagctaaatc tagccgaagg agtaagaggt catttttctg accaggaaat ccaatattga
     5641 gaacataagg gagatgatgt tttcctctat tcaagtaata ctgaatgccc tccagctctg
     5701 ccagaaaggc agtttctaga ttttgtacat gttgaaaatg ttcttcttgt ttttctaggt
     5761 cttcttttag ggctgcaacc atgcctacga tagcaggcag attttcagtt cctgcacgtt
     5821 ttttctgttc ctggtctccg ccatgtagat aggaatcaaa gtccatgcta gatgcgtaga
     5881 gaaaaccgat tcccttagga ccatggaatt tgtgggcaga agcagtgaga aaatcaatgc
     5941 ccaattcttc tgaatgaatt gggattttac caatagcctg aactgcatca acatgatagg
     6001 cagcagggtg ttgcttgagt atttggccaa tttcagcgat gggcagtagg tttcctgtct
     6061 cattattggc aaacatggta gaaaccaaaa tcgtatcgtc acgtaaagcc ttttgaattt
     6121 gctgggctgt gatttcttga ttttctggct ggataatggt tgcttcaaac ccaaagtgtt
     6181 gaaccaagta atcaattgtt tcaaggacag catggtgctc gatggcagtt gtgatgatat
     6241 gttttccttg ttcttggtga cgaagacagt agccaatgat ggtagtatta ttgccttcag
     6301 tcccaccaga agtgaaaaag atatgttgag gttttgtcct tagtaactgg gctagttcct
     6361 gacgggcttc tcgcaagagt ttgccagctt gacgaccatg accatgaata ctagaaggat
     6421 ttccgtgggt ttcttgcata accttggtca tagctgaaat agcaactgct gacataggag
     6481 tcgttgcagc attgtccaaa taaatcaaag aatcacctta tttcttttta ttgtaggcaa
     6541 agagtgggct gactggtttt ctttcgtgaa tacggacgat agcatcacca attaactcac
     6601 tagcagtgat gtagcataca tttttaggag ttttttcttt tgttgctact gaatcagtca
     6661 caagaatttc tttaatatta gtattgtcaa gaagctcagc agctccctcg acgaagagac
     6721 cgtggctaga aacagcataa atttctgtag ctccttcacg ttcaacgatt ttagaagctt
     6781 cagagaaggt acgtcctgta tttaaaatat catcaatcaa gatagctttc ttaccttcaa
     6841 catcaccaat aatataacct tcgttacgag ttgcatcgtc ttgagggtag tcgataatgg
     6901 cgataggagc atcaagatat tcagccaggc tacgcgcacg tttgacacct gaatttttag
     6961 ggctaacgac aacaacatct gaaccaagca atcctttatc gcagtaatgt tttgcgaata
     7021 ggggaacagt gaaaagatta tccactggaa tatcaaagaa accttgaacc tgaacggcat
     7081 gcaaatcaag agtcaggata cgatcaactc cagccttaac cagcatattg gcaactagtt
     7141 ttgctgtaag tggctcacga ggacaagcaa tgcggtcttg acgtgcatag ccaaaatatg
     7201 gaaggacaac gttgatactg tgggcacttg cacgcacaca agcatcgacc atgattaaca
     7261 attccattag gtggttgttg acagggaaac ttgttgattg gatgatgtaa acatcataac
     7321 cacggacact ttcttcgata tttacttgga tttctccgtc tgaaaattga cgtgatgata
     7381 gttttccaag tgggacacca acagcttggg caattttctg tgcaatctct tggttagagt
     7441 tgagtgcgaa aagtttcatg ttttttctat ctgacattat agaccgtcct ctgtaaactt
     7501 tataaatcct agt
//
LOCUS       DAVAGB010000067         7484 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVAGB010000067 DAVAGB010000000
VERSION     DAVAGB010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7484
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.068"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            156..311
                     /locus_tag="VQO19_001948"
                     /pseudo
     CDS             156..311
                     /locus_tag="VQO19_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            511..3786
                     /gene="rexB"
                     /locus_tag="VQO19_001949"
     CDS             511..3786
                     /gene="rexB"
                     /locus_tag="VQO19_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HET1350162.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAEKLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKENSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLKKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3783..7433
                     /gene="addA"
                     /locus_tag="VQO19_001950"
     CDS             3783..7433
                     /gene="addA"
                     /locus_tag="VQO19_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HET1350163.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILNQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWELAKTFQTFMSHFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQKGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEAKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALKMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
BASE COUNT         2281 a         1576 c         1589 g         2038 t
ORIGIN      
        1 cattgtgtac tatttttggt tcattttact atagtagatt gaaataagat acgaacagct
       61 tgattaggga aatcaaatta atttctagaa atattttagc atccacggtg tactattata
      121 gtttcaattt actatagttc aatcattcta tcaagaatat tgaatatata aaggcacgta
      181 atattaaaac ttcttctgat atcgaattag agtccgatgt tgatggcgat aaatcagaca
      241 atctaccagt cgacattaag atactgggac aacacattga agtgtattcc gtacctaaga
      301 aacaatcata aaactcaaag ccttgttacc gaggcttttt tattatgtga ttttcagtag
      361 ccagacttat tctatctaat acaagtaaag ctaagtattt aagatttagc agatgatgaa
      421 gaaaagaaag gatggcctaa atattttaac agatttacga ggctaatcat ggtataatat
      481 agggtgatga aaaattccaa cgaggctgag atgaaattac tttatactga tattcggact
      541 tctttgacag aaattctaac aagagaggca gaagagctag ttgcagctgg caagcgggtc
      601 ttctacattg cccccaactc tctttctttt gaaaaggaac gcgccgtgct ggaatgcttg
      661 tcccagcagg cttctttttc gattaccgtc acgcgctttg ctcaaatggc tcgttatctg
      721 gtcttgaatg atttaccagc taaaactact cttgatgata tcggtcttgg gttggccttt
      781 tacaaatgcc ttgccgaact cgatcccaag gacttgcgtg tttatggcgc tattaagcag
      841 gatcctcaat tgatccagca gttaattgag ctttaccatg agatgaccaa atcccagatg
      901 agttttttgg acttggagaa tttaacagat gaggataaga gggcggattt actcttgatt
      961 tttgagaaag taacagccta tcttaatcaa ggtcagttag cccagggaag tcagttgtcc
     1021 catttgattg aggctattga gaatgacaag gtaagtagtg attttaatca aatcaccttg
     1081 gtcattgacg gctttactcg tttttctgct gaggaagagc gggttgtgga cttacttcac
     1141 ggcaaaggtg ttgagattgt tatcggggct tatgctagta agaaagccta taccagtcct
     1201 tttagcgagg gcaatctcta ccaagccagc gtaaaatttc tccatcatct ggcttctaaa
     1261 taccaaacgc ctgctcagga ctgttctcaa actcatgaga agatggatag ttttgacaag
     1321 gcctctcgtt tgttggagtc ttcttatgac ttttcagaac tcgctttgga tgtcgatgag
     1381 aaagaccgtg aaaatttaca aatctggtct tgtttgacgc aaaaggagga gttggagcta
     1441 gtagcccgta gtattcgtca gaaattacat gagaactcag acctgagcta caagcatttt
     1501 cgtattctct tgggggatgt agcttcttac cagttatctc tcaaaaccat ttttgaccag
     1561 tatcagattc ctttttatct tggtagaagc gaagccatgg ctcatcatcc cttgactcag
     1621 tttgtcgagt ctattttagc tttaaaacgt taccgttttc gtcaggagga tttgattaat
     1681 cttcttagaa ctgatttgta tactgacctc agtcagtctg atattgatgc ttttgagcaa
     1741 tatatccgct atcttggtat caatggcttg ccagcctttc agcaaacctt caccaaatcc
     1801 caccatggaa aatttaatct tgagcgtttg aatgtcctcc gcctgagaat tttagcacct
     1861 cttgaaaccc tctttgccag ccgaaaacaa aaggctgaaa aactcctaca aaaatggagt
     1921 gtctttctaa aagaaggagc tgtgaccaag cagttacaag atttgacaac cactttggaa
     1981 gctgtagaac aggaaagaca agccgaagtt tggaaggctt tctgccatgt tttagaacaa
     2041 tttgcgactg tttttgctgg ttcacaggtt agtctggaag acttcctagc cttgctccat
     2101 tctggaatga gtttgtccca ataccgtacc attccagcaa cagtggacac tgttctggtg
     2161 cagagttacg atttgattgc accattgact gctgactttg tctatgctat tggactaact
     2221 caggacaatt taccaaaaat ttctcaaaac accagtcttc tgacagatga agaaaggcaa
     2281 aatctaaacc aagcgaccga agaaggcgtt caattactga ttgccagcag tgaaaatctc
     2341 aagaaaaatc gctacactat gctttccttg gtcaattctg ctcgtaagca gttgttcttg
     2401 tcggctccaa gcctttttaa cgaaagtgaa agtaaggaat ctgcctatct tcaagagttg
     2461 atccattttg gatttaggcg gagagagaag aggatgaatc acaaaggact gtctaaggag
     2521 gatatggggt cctatcacag tcttttgtct agtctggttg cctatcacca gcagggtgag
     2581 atgagcgata ctgagcaaga tttgactttt gtcaaggttc tgtcgcgtgt cataggtaaa
     2641 aaactagatc agcaaggtct ggaaaatcca gccatcccaa tcagtccaag cagcaagacc
     2701 ttagccaagg acaccttgca agctctctat cctgccaaac aggagtttta cctgtctacg
     2761 tcgggtttga cagagtttta tcgcaatgaa tacagttatt tcctacgcta cgttttaggc
     2821 ttgcaggagg aattacgttt gcgtcctgat gcccgtagtc acgggaattt cttgcatcgt
     2881 atctttgaac gcgccttaca gttgcctaat gaagattcct ttgaccaacg tctagaacaa
     2941 gctattcaag aaaccagtca agaacgcgaa tttgaagcta tttatcaaga aagtttggaa
     3001 gcccagttta ccaaggaagt tttgcttgat gttgcacgga cgactggaca tattctccga
     3061 cacaatccag ccatcgaaac catcaaagaa gaagcaaatt ttggtggaaa agaccaagcc
     3121 tttattcaat tagacaatgg acgtagtgtc tttgtacgag gcaaggtgga ccggattgac
     3181 cgtttgaaag ctaatggagc gataggagta gtagactaca aatccagtct gactcagttc
     3241 cagtttcctc atttctttaa tgggctcaat tctcagttac caacctatct tgctgcccta
     3301 aaaagagaag gggagcagaa ctttttcggc gccatgtact tggaaatggc tgaacctgtc
     3361 caatctctga tggcggtaaa aagtctggca ggagcagtgg tagaagccag caaatctatg
     3421 aaataccaag ggctcttctt ggaaaaagaa aacagttatt taggcgaatt ttataacaaa
     3481 aacaaggcta atcaactgac agatgaggaa tttcagctcc tactggacta caatgcctat
     3541 ctttacaaga aagctgctga gaagatttta gcaggccggt tcgccatcaa tccttatact
     3601 gaaaatggca gaagcattgc cccatacgtc cagcaacatc aggctattac aggctttgaa
     3661 gccaattacc atctgggcca agcccgtttc ctaaaaaagt tggacctagc tgatggcaag
     3721 cgtctggtcg gagaaaaact caagcaagct tggtttgaaa aaataagaga ggagttaaat
     3781 cgatgaagct tattcccttt ttaagtgagg aggagattca aaaactgcaa gaagcagaag
     3841 caaattcgag caaggaacaa aagaaaactg ccgagcaaat cgaagctatc tacacttctg
     3901 gccagaatat cctggtctca gcatcggctg gttctggaaa gacctttgtc atggcagagc
     3961 gcattctgaa ccaattggcg cgtggtgtcg aaatttctca actctttatc tcaaccttta
     4021 ccgtcaaggc tgcaactgaa cttaaagaac gtttagagaa aaaaatcagc aagaaaattc
     4081 aagaaacaga tgatgtcgac ctcaaacaac acttgggacg ccagttggca gacttaccaa
     4141 acgctgccat tggaaccatg gactctttca cacaaaaatt ccttggcaaa catggttatc
     4201 tgcttgatat tgcacctaat ttccgtattt tacaaaacca aagcgagcaa cttcttctcg
     4261 aaaacgaagt ctttcatgag gtctttgaag cgcattacca aggtaaacag aaagagacct
     4321 ttagtcattt gctgaaaaac tttgctgggc gtggcaagga cgaacggggt ctgcgccagc
     4381 aggtctataa aatctatgac ttcctccaat ccaccagtaa tcctcaaaag tggttgagtg
     4441 aatctttcct caaaggcttt gagaaagctg attttaccag tgaaaaagaa aaactgactg
     4501 agcaaatcaa acaagccctt tgggatttgg aaagcttttt ccgttaccat ctggataacg
     4561 atgccaagga gtttgcaaag gctgcctatt tagaaaatgt tcagttaatt ctggatgaaa
     4621 ttggctccct aaatcaggag tccgatagtc aggcttatca ggcagtgctt gcgcgtgttg
     4681 tcgccatctc taaggagaaa aacggtcgag ctctgactaa tgccagtcgt aaggctgatt
     4741 tgaagcccct ggctgatgcc tacaacgaag agagaaagac ccagtttgct aaactaggac
     4801 aattatcaga ccagataacc attctcgact atcaagaacg ttatcatcaa gacacatggg
     4861 aactagctaa aaccttccaa acctttatga gtcattttgt ggaggcttat cgtcagcgca
     4921 aacgccagga aaatgccttt gaattcgctg atatcagcca ttacaccatt gagattttag
     4981 agaatttccc acaagttcgt gagtcttatc aggagcgctt ccatgaagtc atggtcgatg
     5041 agtatcagga taccaaccat attcaagaac ggatgctgga attgttgtct aatggccaca
     5101 atcgctttat ggtgggagat atcaagcaat ccatctatcg tttccgtcag gcagacccgc
     5161 agattttcaa tgagaaattc caacgctatg cgcaaaatcc ccaaaaaggc aagctcattc
     5221 tcctcaagga aaatttccgt agtagttcag aagtgctgtc agcaaccaat gatgtctttg
     5281 aacgtctcat ggaccaagag gtcggcgaaa tcaactatga taacaagcac cagcttgttt
     5341 ttgccaatac caaactgact cccaatccag acaacaaggc agaatttctc ctctacgaca
     5401 aggacgatac aggtgaggaa gaagagagtc aaacagaaac gaaactaaca ggcgaaatgc
     5461 gcttagttat caaggagatt ctgaaacttc atcaagaaaa aggtgttgcc tttaaggaaa
     5521 ttgcccttct gacctccagc cgcagtcgta atgaccagat tctcctcgcc ctgtctgagt
     5581 acggaattcc tgtcaaaact gacggagagc aaaacaatta tctccaatcc ctagaagtgc
     5641 aagtcatgct agacactctt cgtgtcattc acaatcccct gcaagactac gccttggttg
     5701 cccttatgaa gtctccaatg tttggttttg atgaggatga gctagcacgt ttgtcccttc
     5761 agaaagcaga ggataaagtc cacgaaaatc tctatgaaaa actggtcaat gcacaaaaaa
     5821 tggcaagtag tcaaaaaggt ttgattcaca cagctctagc tgaaaaacta aagcaattca
     5881 tggatatcct agcttcttgg cgcttgtatg ccaaaaccca ctctctctat gacttgattt
     5941 ggaagattta caacgaccgt ttttattatg actatgttgg ggctttgccg aatggtcctg
     6001 ctaggcaggc caatctctat gccctagcac tgcgtgctga tcaatttgaa aagagcaatt
     6061 tcaaaggttt gtcgcgtttt attcgtatga ttgaccaagt cttagaagcc cagcacgatt
     6121 tggcaagcgt ggccgtcgca ccgccaaaag atgcagtaga gctcatgacc atccacaaga
     6181 gtaaggggct ggagtttcct tacgtcttta tcctcaatat ggatcaagat ttcaacaagc
     6241 aagactctat gtcagaagtc attctcagtc gtcagaatgg tcttggtgtc aaatatattg
     6301 ccaagatgga gacaggggca gtagaagacc actatcctaa aaccatcaaa ctctccattc
     6361 ctagcctgac ctataggcag aatgaagagg aattacagct agcaagctat tctgagcaga
     6421 tgcgtttgct gtatgttgct atgacgcggg ctgagaaaaa gctctatctt gtcggcaagg
     6481 gttctcgtga aaagctggaa gccaagcaat acccagcagc caaaaatggg aaactaaata
     6541 gcaatactag actgcaagca cggaatttcc aagattggct ttgggctatc agtaaagtgt
     6601 ttactaagga caagctcaac tttagttatc gttttattgg cgaagatcag ttgaccagag
     6661 aagctatcgg agagttggaa accaagagtc ctctccaaga tagctcccaa gcagacaatc
     6721 gtcagtcaga taccatcaaa gaagctctga aaatgctgaa ggaggtggaa gtttataata
     6781 ctcttcaccg cgcagctatt gaacttccta gtgttcaaac cccaagtcaa atcaagaaat
     6841 tctacgaacc agttatggat atggaaggtg tcgagattgc tggtcaaggt cagtcagtag
     6901 gcaagaaaat cagcttcgat ttgccagatt tttcaacaaa agaaaaggta actggagctg
     6961 agattggtag tgctactcac gaactcatgc agagaattga cctcagccag caactaaccc
     7021 ttgctagcct aacagaaaca ctcaaacaag ttcaaactag ccaagctgtc agagacaaga
     7081 tcaatcttga taaaattctt gctttctttg acacagtact cggtcaggaa attcttgcta
     7141 ataccgacca tctctatcgc gagcaacctt tctccatgct caaacgagac caaaagagtc
     7201 aggaagactt tgttgtccgt ggtatccttg atggctatct gctttacgaa aacaaaattg
     7261 ttctgttcga ctacaagaca gaccgctatg atgaaccaag tcaactcgta gaccgctatc
     7321 gtggtcagtt agctctatac gaagaggctt tatcacgagc ctattcgatt gaaaatattg
     7381 aaaaatactt gattttactc ggtaaagacg aggttcaagt tgtaaaagta taacttatac
     7441 tctttgaaaa tctcttcaaa ccacgtcagc ttcgccttgc tgta
//
LOCUS       DAVAGB010000068         7250 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVAGB010000068 DAVAGB010000000
VERSION     DAVAGB010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7250
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.069"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            <1..164
                     /locus_tag="VQO19_001951"
     CDS             <1..164
                     /locus_tag="VQO19_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET1350164.1"
                     /translation="YNHALSKERSKVENIFAKVKTFKIFSTTYRNHRKRFGLRMNLIT
                     GIINHELGF"
     gene            complement(554..2245)
                     /locus_tag="VQO19_001952"
     CDS             complement(554..2245)
                     /locus_tag="VQO19_001952"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HET1350165.1"
                     /translation="MNTKELIASELASIIDNLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2381..2827
                     /gene="argR"
                     /locus_tag="VQO19_001953"
     CDS             2381..2827
                     /gene="argR"
                     /locus_tag="VQO19_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET1350166.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2878..5412
                     /gene="mutS"
                     /locus_tag="VQO19_001954"
     CDS             2878..5412
                     /gene="mutS"
                     /locus_tag="VQO19_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HET1350167.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDCEGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5559..>7250
                     /locus_tag="VQO19_001955"
     CDS             5559..>7250
                     /locus_tag="VQO19_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1350168.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
BASE COUNT         1990 a         1413 c         1700 g         2147 t
ORIGIN      
        1 cctataacca tgcgctatcc aaggagagaa gcaaggttga gaacatcttt gccaaagtaa
       61 aaacgtttaa aatattttca acaacctatc gaaatcatcg taaacgcttc ggattacgaa
      121 tgaatttgat tactggtatt atcaatcatg aactaggatt ctagttttgc aggaagtcta
      181 ttatttggtt aggtgaatta gtgaagcgtt taggcaagtg tctctggtta cgacgtaaag
      241 aagcataaat cgatcatatt tatgtttctt tactagtgaa acgcctagcc aaattaccat
      301 agttacgacg tcatgacctc taaatcgatt atatttaggg gtcatgacta gtgaagcagt
      361 tagctagttc gcatataagc ggctagcgtc taacaattag gaactttagt tccaataact
      421 ttaagattac gacgttttag gacataaatc gatcatattt atgtcctaaa actagtgaag
      481 cgcctagcca aagtccgaat aggatttggc gttagttact tagattgctt tgcaatcaag
      541 taactttggc gatttacatc ttctctggcg cttctactcc aagcaagcga agggcttctt
      601 tgagaacgac tgcggttgcg tagctgaggg ctagacggct gtcgcgttct gggctttcat
      661 ccaagatacg tgtatgtgca tagtatttgt taaaggattg agctaggcta attgcaaatt
      721 tagcaatgat agaaggttca aagttatctg ccgcacggtt gataatacgt gggaagtctt
      781 gaatgagttt aatgatttcc cagctttcag tatcattcaa gctatagttg ccagctgttt
      841 ctggtttgaa atcggctttg cgtaagatag attggatacg agcgtaggca tattgaacgt
      901 aaggtccagt ttcaccctcg aaggatacca tagcctctag gtcgaagtcg tatccatttg
      961 tacggtcggt tttgaggtca tagaatttaa tggctccaac cccaacagca tgtgctactt
     1021 ggtctttgtt ttctagttca ggatttttag cctcgatttg gaccttggca cggctaacag
     1081 cctctgcaac agtaggctct agcaagatga cattcccttt acgagtagag agtttcttcc
     1141 cttcttttgt aaccaaacca aaaggaacgt gagtaatgtc gtcactccag tcgtagccca
     1201 tctcttgcaa gacagctttg agctgtttaa agtgggcaga ttgttcttga ccaacgacat
     1261 agatagattt agcaaattgg tattcgtttt tacggtaaag ggctgcagcc aagtcacgtg
     1321 tgatatagag agttgcacca tcagatttct tgatgagagc tggatgttca attccgtatt
     1381 tctcaagatt gacaacttgg gcaccttctg attcaagaag tagtcctttt tcagaaagaa
     1441 tgtctacaac tgcatccatc ttatcattgt agaaggcttc tccgttatag ctgtcaaatt
     1501 caaccttcaa ttcattgtaa aggcggttaa attccactaa actttcatcg cggaaccatt
     1561 gccaaagagc gagagcttcc tcatctccat tttcaagttt acggaaccat tcgcgcgctt
     1621 cttcatccaa gctagggtca ttttcagctt cagcgttgat gcggacatag agtttaagga
     1681 gttcatcgat tggatgagct tttacagctt cttcgtcgcc ccattttttg taggcaacaa
     1741 tcaacatccc aaattgttta ccccagtctc ccaaatggtt gaccttgacc gtttgataac
     1801 cgattttttg gaaaatatgt gacaagctat ctccgataac agttgaacgc aggtggccaa
     1861 tagaaaatgg tttagcgata ttcggactag acatgtcgat aacaacattt tcttgtttgc
     1921 caatattttg gtcagcatag tgttcttttt cagtggtaac agcttgcaat acttgagcag
     1981 aaatggcaga tttatcaagg aaaaagttaa cgtaaggtcc tgttgcgaca actttttcaa
     2041 aggcttggct gttcattttt tcagccagtt cagccgcaat catttgtggt gctttacgtt
     2101 cgactttggc aagagaaaaa gcagggaaag cgatgtcacc catttctgag tttttagggg
     2161 tttccagtaa ctttaaaata gcctcttggt ccaggttatc aatgatgcta gccaattcgc
     2221 tagcaatcaa ttcttttgta ttcattaaga gctccttttt ggacttttct actattttaa
     2281 cacaatttta aagaaagaag aaaaaatttt tgaaatctcc tgtttttttg gtataatatg
     2341 gttataaata tagttataaa tatgcacgca agaggatttt atgagaaaaa gagatcgtca
     2401 tcagttaata aaaaaaatga ttactgagga gaaattaagt acacaaaaag aaattcaaga
     2461 tcggttggag gcgcacaatg tttgtgtgac gcagacaacc ttgtctcgtg atttgcgcga
     2521 aatcggcttg accaaggtca agaaaaatga tatggtgtat tatgtactag taaatgagac
     2581 agaaaagatt gatttggtgg aatttttgtc tcatcattta gaaggtgttg caagagcaga
     2641 gtttaccttg gtgcttcata ccaaattggg agaagcctct gttttggcaa atattgtaga
     2701 tgtaaacaag gatgaatgga ttttaggaac agttgctggt gccaatacct tattggttat
     2761 ttgtcgagat cagcacgttg ccaaactcat ggaagatcgt ttgctagatt tgatgaaaga
     2821 taagtaaggt cttgggagtt gctctcaaga cttatttttg aaaaggagag acagaaaatg
     2881 gcgatagaaa agctatcacc cggcatgcaa cagtatgtgg atattaaaaa gcaatatcca
     2941 gatgcttttt tgctctttcg gatgggtgat ttttatgaat tattttatga ggatgcggtc
     3001 aatgctgcgc agattctgga aatttcctta acgagtcgca acaagaatgc cgacaatccg
     3061 atccctatgg cgggtgttcc ctatcattct gcccaacagt atatcgatgt cttgattgag
     3121 cagggttata aggtggctat cgcagagcag atggaagatc ctaaacaagc agttggggtt
     3181 gttaaacgag aggttgttca ggtcattacg ccagggacag tggtcgatag cagtaagccg
     3241 gacagtcaga ataatttttt ggtttccata gactgcgaag gcaatcaatt tggcctagct
     3301 tatatggatt tggtgacggg tgacttttat gtgacaggtc ttttggattt cacgctggtt
     3361 tgtggggaaa tccgtaacct caaggctcga gaagtggtgt tgggttatga cttgtctgag
     3421 gaagaagaac aaatcctcag ccgccagatg aatctggtac tctcttatga aaaagaaagc
     3481 tttgaagacc ttcatttatt ggatttgcga ttggcaacgg tggagcaaac ggcatctagt
     3541 aagctgctcc agtatgttca tcggactcag atgagggaat tgaaccacct caaacctgtt
     3601 atccgctacg aaattaagga tttcttgcag atggattatg cgaccaaggc tagtctggat
     3661 ttggttgaga atgctcgctc aggtaagaaa caaggcagtc ttttctggct tttggatgaa
     3721 accaaaacgg ctatggggat gcgtctcttg cgttcttgga ttcatcgccc cttgattgat
     3781 aaggaacgaa tcgtccaacg tcaagaagta gtgcaggtct ttctcgacca tttctttgag
     3841 cgtagtgact tgacagacag tctcaagggt gtttatgaca ttgagcgctt ggctagtcgt
     3901 gtttcttttg gcaaaaccaa tccaaaggat ctcttgcagt tggcgactac cttgtctagt
     3961 gtgccacgga ttcgtgcgat tttagaaggg atggagcaac ctactctagc ctatctcatc
     4021 gcacaactgg atgcaatccc tgagttggag agtttgatta gcgcagcgat tgctcctgaa
     4081 gctcctcatg tgattacaga tgggggaatt atccggactg gatttgatga gactttagac
     4141 aagtatcgtt gcgttctcag agaagggact agctggattg ctgagattga ggctaaggag
     4201 cgagaaaact ctggtatcag cacgctcaag attgactaca ataaaaagga tggctactat
     4261 tttcatgtga ccaattcgca actaggaaat gtgccagccc actttttccg caaggcgacg
     4321 ctgaaaaact cagaacgctt tggaaccgaa gaattagccc gtatcgaggg agatatgctt
     4381 gaggcgcgtg agaagtcagc caacctcgaa tacgaaatat ttatgcgcat tcgtgaagag
     4441 gtcggcaagt acatccagcg tttacaagct ctagcccaag gaattgcgac ggttgatgtc
     4501 ttacagagtc tggcggttgt ggctgaaacc cagcatttga ttcgacctga gtttggtgac
     4561 gattcacaaa ttgatatccg gaaagggcgc catgctgtcg ttgaaaaggt tatgggggct
     4621 cagacctata ttccaaatac gattcagatg gcagaagata ccagtattca actggttaca
     4681 gggccaaaca tgagtgggaa gtctacctat atgcgtcagt tagccatgac ggcggttatg
     4741 gcccagctgg gttcctatgt tcctgctgaa agcgcccatt taccgatttt tgatgcgatt
     4801 tttacccgta tcggagcagc agatgacttg gtttcgggtc agtcaacctt tatggtggag
     4861 atgatggagg ccaataatgc catttcgcat gcgaccaaga actctctcat tctctttgat
     4921 gaattgggac gtggaactgc aacttatgac gggatggctc ttgctcagtc catcatcgaa
     4981 tatatccatg agcacatcgg agctaagacc ctctttgcga cccactacca tgagttgact
     5041 agtctggagt ctagtttaca acacttggtc aatgtccacg tggcaacttt ggagcaggat
     5101 gggcaggtca ccttccttca caagattgaa ccgggaccag ctgataaatc ctacggtatc
     5161 catgttgcca agattgctgg cttgccagca gaccttttag caagggcgga taagattttg
     5221 actcagctag agaatcaagg aacagagagt cctcctccca tgagacaaac tagtgctgtc
     5281 actgaacaga tttcactctt tgatagggca gaagagcatc ctatcctagc agaattagct
     5341 aaactggatg tgtataatat gacacctatg caggttatga atgtcttagt agagttaaaa
     5401 cagaaactat aaaaccaaga ctcactagtt aatctagctg tatcaaggag acttctttga
     5461 caattctcca cttttttgct agaataacat cacacaaaca gaatgaaaag gagctgacgc
     5521 attgtcgctc ccttttgtct attttttaag gagaaagtat gctgattcag aaaataaaaa
     5581 cctacaagtg gcaggccctg gcttcgctcc tgatgacagg cttgatggtt gctagttcac
     5641 ttctgcaacc gcgttatctg caggaagtct taggcgccct ccttactggg aaatatgaag
     5701 ctatttatag tatcggggct tggttgattg gtgtggccgt agtcggtcta gttgctggtg
     5761 gactcaatgt tgtcctcgca gcctatattg cccaaggagt ttcatccgac cttcgggagg
     5821 atgccttccg taaaattcaa accttttctt atgctgatat tgaacaattt aatgcgggaa
     5881 atctagtcgt tcgaatgaca aatgatatca accagattca gaacgttgtc atgatgacct
     5941 tccaaattct tttcagactt cccctcttgt tcatcggttc gtttatccta gcggttcaaa
     6001 ccttaccttc tctgtggtgg gtgattgttc tcatggtagt cttgattttt ggtttgactg
     6061 ctgtcatgat gggaatgatg gggcctcgtt ttgccaagtt tcaaaccctt cttgagcgca
     6121 tcaatgccat tgccaaggaa aatttacgtg gcgttcgtgt ggtcaagtcc tttgtccaag
     6181 aaaaagagca atttgctaag tttacagagg tctcagacga gcttcttggt caaaaccttt
     6241 acattggtta tgccttttca gtagtggaac cctttatgat gttggttggt tacggggcgg
     6301 tcttcctctc tatttggctg gtcgcgggaa tggttcagtc ggatccgtct gttgttggtt
     6361 ccatcgcttc ttttgttaat tacctaagcc agattatctt taccattgtt atggttggat
     6421 ttttgggaaa ttctgtcagc cgtgccatga tttccatgcg tcgtattcga gaaattcttg
     6481 acgcagagcc agctatgacc ttcaaggata tcccagatga agagttggtt ggaagcctta
     6541 gctttgaaaa tgtgaccttt acctatccaa tggacaagga accgatgctg aaagatgtga
     6601 gctttactat tgaacctggt caaatggttg gtgtagttgg agcgactggt gcaggaaagt
     6661 caaccttggc tcaattgatt ccacgtctct ttgatccaca ggaaggggct atcaaaatcg
     6721 gaggtaagga tattcgagaa gtgagtgaag gaaccctgcg taaaacagtt tccatcgttc
     6781 tccaacgtgc cattcttttt agtggaacga ttgcagataa cttgagacag gggaagggaa
     6841 atgctactct atttgaaatg gagcgcgcag ccaatattgc ccaggctagt gaattcattc
     6901 atcgtatgga gaaaaccttt gaaagtccag ttgaagaacg gggaaccaat ttctctggtg
     6961 gacaaaaaca aaggatgtcg attgcgcgtg ggattgtcag caatccacgt attctgattt
     7021 ttgatgattc gacctcagcc ttggatgcca aatcagagcg cttggtgcaa gaagctttga
     7081 ataaggactt gaaggggacg acaaccatta ttattgctca aaaaattagc tcggttgtcc
     7141 atgcagacaa gatcttggtt ctaaatcaag gacgattgat tggtcaaggc acgcatgcag
     7201 acttggttgc caacaatgcc gtttaccgtg aaatctatga aacacagaaa
//
LOCUS       DAVAGB010000069         7246 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVAGB010000069 DAVAGB010000000
VERSION     DAVAGB010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7246
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.070"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            226..6642
                     /locus_tag="VQO19_001956"
     CDS             226..6642
                     /locus_tag="VQO19_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HET1350169.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSNSEDALSISDKEKV
                     AENKEKHENIHSAIETSQDFKEKKTAVIEGKEVVSKNPVTDNNTSNEEARIKEDSNQS
                     QGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSNLKNTKVLYTYDRIFN
                     GSAIETTPDNLDKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFGK
                     NFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAFN
                     YYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSYK
                     MYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAGI
                     PMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFDK
                     VNIGGQSFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKIA
                     VMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQVF
                     SISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKEI
                     DFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKSTY
                     GYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQNTARP
                     MMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLKE
                     IKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGKQIVPE
                     IHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEMEA
                     LNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGKPKIPG
                     TLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSGSKIAN
                     IYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVISREHFI
                     RGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQF
                     EPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTYH
                     KVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQG
                     RNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANRADENGMISYY
                     LVDPDKDASKYEKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKEKSSFT
                     IDRNISTIRDFENKDLKKLIKKKFREVDDFVTGGKRTVELDYKYDDKGNITAYEDESA
                     LEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEIKATKY
                     DSHSKTMTFDLYANINDIVDGLAFAGDMRFFVKDDDRIKAETKIRMPEKNKETKAEYP
                     YVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKVT
                     TYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQAVLMS
                     ALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKSNVEAI
                     KEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVNE
                     SVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYLQ
                     TGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFDG
                     EIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSEL
                     KPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGYVI
                     NLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDHS
                     QKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLGL
                     KKKNQD"
     gene            complement(6971..>7246)
                     /locus_tag="VQO19_001957"
     CDS             complement(6971..>7246)
                     /locus_tag="VQO19_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET1350170.1"
                     /translation="PEKFFGLIEDNLKQVHPIFQTVFKTFLKNKEKIVNALQLPYSNA
                     KLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSQA"
BASE COUNT         2826 a          973 c         1406 g         2041 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggagt ttaaataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taaccacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctaactc tgaagatgct ttaagcatct ctgataaaga aaaagtagca
      361 gaaaataaag agaaacatga aaatatccat agtgctatag aaacttcaca ggattttaaa
      421 gagaagaaaa cagcagtcat tgagggaaaa gaagttgtta gtaaaaatcc tgtgacagac
      481 aataacacta gcaatgaaga agcaagaatc aaagaagatt ccaatcaatc ccaaggagat
      541 catacggact catttgtgaa taaaaacaca gaaaatccca aaaaagaaga taaagttgtc
      601 tatattgctg aatttaaaga taaagaatct ggagaaaaag caatcaagca actatccaat
      661 cttaagaata caaaagtttt atatacttat gatagaattt ttaacggtag tgccatagaa
      721 acaactccag ataacttgga caaaattaaa caaatagaag gtattacatc ggttgaaagg
      781 gcacaaaaag tccaacccat gatgaatcat gccagaaagg aaattggagt tgaggaagct
      841 attgattacc taaagtctat caatgctccg tttgggaaaa attttgatgg tagaggtatg
      901 gtcatttcaa atatcgatac tggaacagat tatagacata aggctatgag aatcgatgat
      961 gatgccaaag cctcaatgag atttaaaaaa gaagacttaa aaggaactga taaaaattat
     1021 tggttgagtg ataaaatccc tcatgcgttc aattattata atggtggcaa aatcactgta
     1081 gaaaaatatg atgatggaag ggattatttt gacccacatg ggatgcatat tgcagggatt
     1141 cttgctggaa atgatactga acaagatatc aaaaacttta acggcataga tggaattgcg
     1201 cctaatgcac aaattttctc ttataaaatg tattctgacg caggatctgg gtttgcgggt
     1261 gatgaaacaa tgtttcatgc tattgaagat tctatcaaac acaacgttga tgttgtttcg
     1321 gtatcatctg gttttacagg aacaggtctt gtaggtgaga aatattggca agctattagg
     1381 gcattaagaa aagcaggcat tccaatggtt gtcgctacgg gtaactatgc gacttctgct
     1441 tcaagttctt catgggattt agtagcaaat aatcatctga aaatgaccga cactggaaat
     1501 gtaacacgaa ctgcagcaca tgaagatgcg atagcggtcg cttctgctaa aaatcaaaca
     1561 gttgagtttg ataaggttaa cattggagga caaagtttta aatacagaaa tataggggcc
     1621 tttttcgata agaataaaat cacaacaaat gaagatggaa caaaagctcc tagtaaatta
     1681 aaatttgtat atataggcaa ggggcaagac caagatttga taggtttgga tcttaggggc
     1741 aaaattgcag taatggatag aatttataca aaggatttaa aaaatgcttt taaaaaagct
     1801 atggataagg gtgcacgcgc cattatggtt gtaaatactg taaattacta caatagagat
     1861 aattggacag agcttccagc tatgggatat gaagcggatg aaggtactaa aagtcaagtg
     1921 ttttcaattt caggagatga tggtgtaaag ctatggaaca tgattaatcc tgataaaaaa
     1981 actgaagtca aaagaaataa taaagaagat tttaaagata aattggagca atactatcca
     2041 attgatatgg aaagttttaa ttccaacaaa ccgaatgtag gtgacgaaaa agagattgac
     2101 tttaagtttg cacctgacac agacaaagaa ctctataaag aagatatcat cgttccagca
     2161 ggatccacat cttgggggcc aagaatagat ttacttttaa aacccgatgt ttcagcacct
     2221 ggtaaaaata ttaaatccac gcttaatgtt attaatggca aatcaactta tggctatatg
     2281 tcaggaacta gtatggcgac tccaatcgtg gcagcttcta ctgttttgat tagaccgaaa
     2341 ttaaaggaaa tgcttgaaag acctgtattg aaaaatctta agggagatga caaaatagat
     2401 cttacaagtc ttacaaaaat tgccctacaa aatactgcgc gacctatgat ggatgcaact
     2461 tcttggaaag aaaaaagtca atactttgca tcacctagac aacagggagc aggcctaatt
     2521 aatgtggcca atgctttgag aaatgaagtt gtagcaactt tcaaaaacac tgattctaaa
     2581 ggtttggtaa actcatatgg ttccatttct cttaaagaaa taaaaggtga taaaaaatac
     2641 tttacaatca agcttcacaa tacatcaaac agacctttga cttttaaagt ttcagcatca
     2701 gcgataacta cagattctct aactgacaga ttaaaacttg atgaaacata taaagatgaa
     2761 aaatctccag atggtaagca aattgttcca gaaattcacc cagaaaaagt caaaggagca
     2821 aatatcacat ttgagcatga tactttcact ataggcgcaa attctagctt tgatttgaat
     2881 gcggttataa atgttggaga ggccaaaaac aaaaataaat ttgtagaatc atttattcat
     2941 tttgagtcag tggaagaaat ggaagctcta aactccaacg ggaagaaaat aaacttccaa
     3001 ccttctttgt cgatgcctct aatgggattt gctgggaatt ggaaccacga accaatcctt
     3061 gataaatggg cttgggaaga agggtcaaga tcaaaaacac tgggaggtta tgatgatgat
     3121 ggtaaaccga aaattccagg aaccttaaat aagggaattg gtggagaaca tggtatagat
     3181 aaatttaatc cagcaggagt tatacaaaat agaaaagata aaaatacaac atccctggat
     3241 caaaatccag aattatttgc tttcaataac caagggatca acgctccatc atcaagtggt
     3301 tctaagattg ctaacattta tcctttagat tcaaatggaa atcctcaaga tgctcaactt
     3361 gaaagaggat taacaccttc tccacttgta ttaagaagtg cagaagaagg attgatttca
     3421 atagtaaata caaataaaga gggagaaaat caaagagact taaaagtcat ttcgagagaa
     3481 cactttatta gaggaatttt aaattctaaa agcaatgatg caaagggaat caaatcatct
     3541 aaactaaaag tttggggtga cttgaagtgg gatggactca tctataatcc tagaggtaga
     3601 gaagaaaatg caccagaaag taaggataat caagatcctg ctactaagat aagaggtcaa
     3661 tttgaaccga ttgcagaagg tcaatatttc tataaattta aatatagatt aactaaagat
     3721 tacccatggc aggtttccta tattcctgta aaaattgata acaccgctcc taagattgtt
     3781 tcggttgatt tttcaaatcc tgaaaaaatt aagttgatta caaaggatac ttatcataag
     3841 gtaaaagatc agtataagaa tgaaacgcta tttgcgagag atcaaaaaga acatcctgaa
     3901 aaatttgacg agattgcgaa tgaagtttgg tatgctggcg ccgctcttgt taatgaagat
     3961 ggagaggttg aaaaaaatct tgaagtaact tacgcaggtg agggtcaagg aagaaataga
     4021 aaacttgaca aagacggaaa taccatttat gaaattaaag gtgcaggaga tttaagagga
     4081 aaaatcattg aagtcattgc attagatggt tctagcaatt tcacaaagat tcatagaatt
     4141 aaatttgcta atcgggctga tgaaaatggg atgatttctt attacctagt agatcctgac
     4201 aaagatgctt ctaaatatga aaaacttggc gagattgcag aatctaaatt taaaaattta
     4261 ggaaatggaa aagagggtag tctaaaaaaa gatacaactg gggtagaaca tcatcatcaa
     4321 gaaaatgaag agtctattaa agaaaaatct agttttacta ttgatagaaa tatttcaaca
     4381 attagagact ttgaaaataa agacttaaag aaactcatta aaaagaaatt tagagaagtt
     4441 gatgactttg taactggtgg aaaaagaaca gtagaacttg attataaata tgacgataaa
     4501 ggaaatataa ctgcctatga agatgaaagt gctctagaat atgaaactga aaaatttgac
     4561 gaaataaaat caaaaattta tggtgttcta agcccatcta aagatggaca ctttgaaatt
     4621 cttggaaaga taagcaatgt ttctaaaaat gccaaggtat attatggaaa taactataaa
     4681 tttatagaaa tcaaagcgac taagtatgac tcacattcaa aaacgatgac atttgattta
     4741 tacgctaata ttaatgatat tgtggatgga ttagcttttg ctggagatat gcggtttttt
     4801 gttaaagatg atgatcgaat aaaagctgaa actaaaatta gaatgcctga aaaaaataag
     4861 gaaactaaag cagaatatcc ctatgtatca agttatggga atgtaatcga attaggagaa
     4921 ggagatcttt caaagaacaa accagacaat ttaactaaaa tggaatctgg taaaatctat
     4981 tctgattcag aaaaacaaca atatctgtta aaggataaca tcattctaag aaaaggctat
     5041 gcactaaaag tgactaccta taatcctgga aaaacggata tgttagaagg gaatggagtc
     5101 tatagcaagg aagatatagc aaaaatacaa aaggccaatc ctaatctaag agtcctttca
     5161 gaaacaacaa tttatgctga tagtagaaat gttgaagatg gaagaagtac ccaagctgta
     5221 ttaatgtcgg ctttggacgg ctttaacatt ataaggtatc aagtgtttac atttaaaatg
     5281 aacgataaag gggaagctat cgataaagac ggaaatcttg tgacagattc ttctaaactt
     5341 gtattatttg gtaaggatga taaagaatac actggagagg ataagtccaa tgtagaagct
     5401 ataaaagaag atggctccat gttatttatt gataccaaac cagtaaacct ttcaatggat
     5461 aagaactact ttaatccatc taaatctaat aaaatttatg tacgaaatcc agaattttat
     5521 ttaagaggta agatttctga taagggtggt tttaactggg aattgagagt taatgaatcg
     5581 gttgtagata attatttaat ctacggagat ttacacattg ataacactag agattttaat
     5641 attaagttga atgttaaaga cggtgacatc atggactggg gaatgaaaga ctataaagca
     5701 aacggatttc cagataaggt aacagatatg gatggaaatg tttatcttca aactggctat
     5761 agcgatttga atgctaaagc agttggagtc cactatcagt ttttatatga taatgttaaa
     5821 cccgaagtaa acattgatcc taagggaaat actagtatcg aatatgctga tggaaaatct
     5881 gtagtcttta acatcaatga taaaagaaat aatggattcg atggtgagat tcaagaacaa
     5941 catatttatg taaatggaaa agaatataca tcatttgatg atattaaaca aataacagac
     6001 aagacactaa acattaagat tgttgtaaaa gattttgcaa gaaatacaac cgtaaaagaa
     6061 ttcattttaa ataaagatac gggagaggta agtgaattaa aacctcatag ggtaactgtg
     6121 accattcaaa atggaaaaga aatgagttca acgatagtgt cggaagaaga ttttatttta
     6181 cctgtttata agggtgaatt agaaaaagga taccaatttg atggttggga aatttctggt
     6241 ttcgaaggta aaaaagacgc tggctatgtt attaatctat caaaagatac ctttataaaa
     6301 cctgtattca agaaaataga ggagaaaaag gaggaagaaa ataaacctac ttttgatgta
     6361 tcgaaaaaga aagataaccc acaagtaaac catagtcaat taaatgaaag tcacagaaaa
     6421 gaggatttac aaagagaaga tcattcacaa aaatctgatt caactaagga tgttacagct
     6481 acagttcttg ataaaaacaa tatcagtagt aaatcaacta ctaacaatcc taataagttg
     6541 ccaaaaactg gaacagcaag cggagcccag acactattag ctgccggaat aatgtttata
     6601 gtaggaattt ttcttggatt gaagaaaaaa aatcaagatt aagacaaaag ctatagaaaa
     6661 aaatggttta tgtactgaga ttagatagtg aggtgatgac atagttttgt gaaaacagcc
     6721 atttataact caattattta gtttacttca ctattgatac tatttggagt tattaatgga
     6781 cttagtttag ataactaatg aattgattga aagggttagt attgacaata ttggtcatat
     6841 tgattagaaa atagagtcta tcaaaattta aaggctaata gaggtgatga gacaatttca
     6901 aggaattaag tagcgtttgg ttgcttaatt ccttttggct ctttgtcaac tgtagtgggt
     6961 tgaagaaaag ctaagcttga gaaaggacaa atttcgtcct ttcttttttg atgttcagag
     7021 cgataaaaat ccgttttttg aagttttcaa agtttcgaaa accaaaggca ttgcgtttga
     7081 taagtttgat gagattattg gtcgcttcca atttggcgtt tgaatagggt agttgaaggg
     7141 cgttgacgat tttctctttg ttctttagaa aggttttaaa gacagtctga aaaataggat
     7201 gaacctgctt cagattgtcc tcaatgagtc cgaaaaattt ctcagg
//
LOCUS       DAVAGB010000070         7111 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVAGB010000070 DAVAGB010000000
VERSION     DAVAGB010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7111
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.071"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            1..690
                     /locus_tag="VQO19_001958"
                     /pseudo
     CDS             1..690
                     /locus_tag="VQO19_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            776..1726
                     /locus_tag="VQO19_001959"
     CDS             776..1726
                     /locus_tag="VQO19_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET1350171.1"
                     /translation="MGKKRWARNGSESNDASYAQVVSLYDDTSISVSNNETDKVLTGS
                     LYTETNEQGLTIPSSLLKNWNEQTGKNLTTNDLIGKSVSASIVESAAETSKIAQFQTK
                     IVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTEELQK
                     NKKYTVFSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRSKEIG
                     VMKAVGYQNRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSITKVFE
                     LNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1903..2910
                     /gene="gap"
                     /locus_tag="VQO19_001960"
     CDS             1903..2910
                     /gene="gap"
                     /locus_tag="VQO19_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HET1350172.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2977..3813)
                     /locus_tag="VQO19_001961"
     CDS             complement(2977..3813)
                     /locus_tag="VQO19_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET1350173.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLARCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            3939..6134
                     /locus_tag="VQO19_001962"
     CDS             3939..6134
                     /locus_tag="VQO19_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET1350174.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMASQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQVVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            6187..6339
                     /gene="rpmG"
                     /locus_tag="VQO19_001963"
     CDS             6187..6339
                     /gene="rpmG"
                     /locus_tag="VQO19_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET1350175.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6349..6525
                     /gene="secE"
                     /locus_tag="VQO19_001964"
     CDS             6349..6525
                     /gene="secE"
                     /locus_tag="VQO19_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HET1350176.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6580..>7111
                     /gene="nusG"
                     /locus_tag="VQO19_001965"
     CDS             6580..>7111
                     /gene="nusG"
                     /locus_tag="VQO19_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HET1350177.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
BASE COUNT         2229 a         1253 c         1527 g         2102 t
ORIGIN      
        1 aaggaacaaa accaagaaag gttgatagag atagacttaa aaactatctt actgacaatc
       61 cagacgctta tttgactgaa atagcttctg aatttggctg tcatccaact accatccact
      121 atgcgctcaa agctatgggc tacactcgaa aaaaagaacc acacctacta tgaacaagac
      181 ccagaaaaag tagccttatt tcttaaaaat tttaatagtt taaagcacct agcacctgtt
      241 tagattgatg aaacaggatt cgatacttat ttttatcgag aatatggtcg ctcattaaaa
      301 ggtcagttaa gaagaggtaa agtatctgga agaagatatc agaggatttc tttggttgca
      361 ggtctaacaa atggtgagtt aatcgctcca atgacttacg aagagatgat gacgagcgac
      421 ttttttgaag cttggtttca gaagtttctc ttaccaacat taaccacacc atcggttatt
      481 attatggata atgcaagatt ccatagaatg ggtaagttag aacttttatg cgaggagttt
      541 gggcataaac ttttacctct tcctccctac tcacctgagt acaatcctat tgagaaaaca
      601 tgggctcata tcaaaaagca cctcaaaaag gtattaccaa gttgcaatac cttttatgag
      661 gctcttttgt cctgctcttg tttcaattga ctatagttca cggatacagt tgggaaagaa
      721 gctattaaat atttggagag tccttttggg atgaacatgt caaatattac tatagatggg
      781 caagaaaaga tgggcaagaa atggatctga gtcaaacgat gcttcttatg ctcaagtagt
      841 gagtctttat gatgatacaa gtatctctgt tagtaataat gagacggaca aagtgttgac
      901 tggatccctc tatactgaaa caaatgaaca gggattaacg attccaagca gtttactaaa
      961 aaattggaat gaacagacag gaaaaaattt gacaactaat gatcttattg gcaaatcagt
     1021 ctcagccagc attgtagaaa gtgctgccga aactagtaag attgctcaat ttcaaacgaa
     1081 gattgtacgt gtaatcaatg atgaagatga catggaggac agcaacagtt tcatgctgtc
     1141 tcatcaaatg gaaacgattt tgaaagaggc tggatttacg aaagctgtat cttattttat
     1201 cttggaactc aaagatccat cacagacaaa agtagtaaca gaagaattac agaaaaataa
     1261 gaagtatact gtgttttctc aacagagagt tcttgatatt gtgattacct ttattcgtgt
     1321 tattcaggga ttattgattg tgctttcatc acaagctatt gtggtagcag cggttatgat
     1381 tggtatcatt atttacatca atatcatgca acgttccaag gaaataggtg tcatgaaagc
     1441 agttggttat cagaatcgtg gtgtcaaagg aatttttatt tacgaggcta tctggattgt
     1501 aggcatcgcc ttgctgctgg catttttggt tgcacaaggg gtgggaagtt tggcgaatgc
     1561 gattgtaagt cacttttacc catccatcac taaggttttt gaattaaatc ttttatctgt
     1621 tttaggaact ctagttttcg ctctattact tggttatgtc tcagcctact tcccggcgcg
     1681 taagattagt aaaatggatc ctgtagaatc gttacgctat gaataataag ggattccttg
     1741 atttacagtc ttaaaaagaa actcacatag aaaaacaatg gccatacttg caattcaact
     1801 caaatagttg tataataggt ttgttgaaag gtgatttgta gtgattcaag ttactctttt
     1861 cacaataaaa atttcatgat tttcataagg aggaaatcac taatggtagt taaagttggt
     1921 attaacggtt tcggacgtat cggtcgtctt gctttccgtc gtatccaaaa cgtagaaggt
     1981 gttgaagtta cacgcatcaa cgaccttaca gatccagtta tgcttgcaca cttgttgaaa
     2041 tacgacacaa ctcaaggtcg tttcgacggt actgttgaag ttaaagaagg tggattcgaa
     2101 gttaacggta aattcgttaa agtttctgct gaacgtgatc cagagcaaat cgactgggct
     2161 actgacggtg tagaaatcgt tcttgaagct actggtttct ttgctaagaa agaagcagct
     2221 gaaaaacacc ttaaaggtgg agctaaaaaa gttgttatca ctgctcctgg tggaaacgac
     2281 gttaaaacag ttgtattcaa cactaaccac gacgttcttg acggtactga aacagttatc
     2341 tcaggtgctt catgtactac aaactgcttg gctccaatgg ctaaagctct tcaagataac
     2401 tttggtgttg ttgaaggatt gatgactact atccacgctt acactggtga ccaaatgatc
     2461 cttgacggac cacaccgtgg tggtgacctt cgccgtgctc gcgctggtgc tgcaaacatc
     2521 gttcctaact caactggtgc tgctaaagct atcggtcttg taatcccaga attgaacggt
     2581 aaacttgacg gatctgcaca acgcgttcca actccaactg gatcagttac tgaattggta
     2641 gcagttcttg aaaagaacgt tactgttgat gaagtgaacg cagctatgaa agcagcttca
     2701 aacgaatcat acggttacac agaagatcca atcgtatctt cagatatcgt aggtatgtct
     2761 tacggttcat tgtttgacgc aactcaaact aaagttcttg acgttgacgg taaacaattg
     2821 gttaaagttg tatcatggta cgacaacgaa atgtcataca ctgcacaact tgttcgtact
     2881 cttgaatact tcgcaaaaat tgctaaataa ttcttgagtt gatagaaagc aaggctttgt
     2941 ggtcttgctt tttatatgga aaaatggatg acacgatcat ccattctttt ttaattcttt
     3001 ttcaaatgta tttgaaaggg tagtgaaagt tagcttctct aaagtaagtg ggtgggtaaa
     3061 ggaaagtcgg aaggcatgaa gcataagccg acttgtcttt gatttactat tatagagagg
     3121 gtcgcccagg ataggaagat tatgatgcga aaggtgcaca cgaatctgat gggttcgccc
     3181 tgtctttagc ttgcaacgag ccaaggaagt cttgtttgag aattgcttta acctgcttac
     3241 atgcgtttca gcatattgcc cattttttgc atcaactatt ctttttctac gatcatggcg
     3301 atcacgtcca attttgtctc tgaaaacaag ttcttttctg ttgatatttc catcaactag
     3361 agcccaatat tctctagaaa tctctttttt ctccaataag cgattgagaa tgggcaggat
     3421 aaaaggattt ttggcaaaga gaactaagcc actggtttcc atgtccagac gatgaacgac
     3481 atagcaggtt tggccaacat aggtactgac atggttaaga agggcaattt cgtttggttg
     3541 attaccatgc gttttcatcc cctctggttt gtttacaata atcaagtgtt gatcttgata
     3601 aacttcctgc actaagtctg ggttgcccca agggatcgtc ttttgggaat aatcttcctc
     3661 gtcaaaagtc aactggcaaa catctccagg atttacgatt tcgttccagt ggacttcttc
     3721 ttgatttatc aaaatatgtt tcttgattct caaaaaatga cggatttttc tagggatgag
     3781 gagttgttcc tcaagtaatt gctttaccgt catttgaggt agagaggcgg gtaatgtaaa
     3841 tgtgaattgc atacagatat tgtaacaaaa aaagccctat ttggatagga aatagctaaa
     3901 ttcttgtctt cctatgatga agatgataaa ataaacgcat gaaattagat aaattatttg
     3961 agaaatttct ttctcttttt aaaaaagaaa caagtgaact agaggactct gattctacta
     4021 tcttacgtcg ctctcgtagt gatcgaaaaa aattagccca agtaggtccg attcgaaaat
     4081 tctggcgtcg ttatcatcta acaaagatta tccttatact aggtttgagt gcaggcttgc
     4141 tagttggaat ctatttgttt gctgtagcca agtcaaccaa tgtcaatgat ttgcaaaatg
     4201 ccttgaaaac tcgaactctt atttttgacc gtgaagaaaa agaggctggt gccttgtctg
     4261 gtcaaaaggg aacctatgtt gagctgactg acatcagtaa aaacttgcag aatgctgtta
     4321 ttgcgacaga agaccgttct ttctataaaa atgacgggat taactatggc cgtttcttct
     4381 tggctattgt cactgctggc cgttcaggtg gtggctctac cattacccaa cagctggcta
     4441 aaaacgccta tttatcgcag gatcaaactg ttgagagaaa agcgaaagaa tttttccttg
     4501 ccttagaatt aagcaaaaaa tatagtaagg agcaaattct aaccatgtac cttaacaacg
     4561 cttattttgg aaatggtgtg tggggtgtag aagatgcgag taagaaatac tttggagttt
     4621 ctgcatcaga agtgagtctg gatcaagctg cgactctggc agggatgctc aaggggccgg
     4681 aactgtataa tcccttgaat tccgtagaag attctactaa tcggcgcgat actgtcttgc
     4741 agaatatggt tgcagcagga tatattgata aaaaccaaga aaccgaagct gctgaagttg
     4801 atatggcttc gcaattgcac gataagtatg aaggaaaaat ctcagattac cgttacccct
     4861 cttattttga tgcggtggtt aatgaagctg tttccaagta taatctaaca gaggaagaga
     4921 ttgtcaataa tggctaccgc atttacacag agctggacca aaactaccaa gcaaatatgc
     4981 aggttgttta tgaaaacaca tcgctatttc cgagggcaga ggatggaacg tttgctcaat
     5041 caggaagtgt agctctcgaa ccgaaaacag ggggagttcg tggagttgtc ggtcaagttg
     5101 ctgacaatga taaaactgga ttccggaatt tcaactatgc aacccaatca aagcgtagtc
     5161 ctggttctac aattaagcct ttagttgttt atacgccagc agttgaagca ggctgggctt
     5221 tgaataagca gttggataac cataccatgc agtatgacag ctataaggtt gataactatg
     5281 cagggatcaa aacgagtcga gaagttccta tgtatcaagc cttggcagaa tcgcttaatc
     5341 tacctgctgt tgccactgtt aatgatttgg gtgtcgacaa ggcttttgag gcaggcgaaa
     5401 aattcggact caacatggaa aaggtcgacc gtgttcttgg tgtcgccttg ggaagcggtg
     5461 ttgaaaccaa ccctcttcaa atggctcaag catacgccgc ctttgcaaat gaaggtttaa
     5521 tgcctgaagc tcattttatt agtagaattg aaaatgctag tggacaagtt attgcgagtc
     5581 ataaaaattc acaaaaacgg gtgattgata agtctgtagc tgacaagatg accagtatga
     5641 tgttggggac tttcaccaac ggtaccggta ttagttcatc gcctgcagac tatgtcatgg
     5701 cagggaaaac tggaacaact gaagcagttt tcaatccgga gtacacaagt gaccagtggg
     5761 taattggtta tactccggat gtagtgatta gccactggct tggctttccg accactgatg
     5821 aaaaccatta tctagctggc tctacttcaa acggtgcagc tcatgtcttt agaaacattg
     5881 ccaataccat tttaccttat acgccaggaa gtacctttac ggttgaaaat gcttataagc
     5941 aaaatggaat tgcaccagcc aatacaaaaa gacaagtaca aaccaatgat aatagccaga
     6001 cagatgataa tttgtctgat attcgagggc gtgcgcaaag tctagtagat gaggctagcc
     6061 gggctatctc agatgcgaag attaaggaaa aggctcaaac aatatgggat tcgatagtca
     6121 atctatttcg ctaagatgct tgtcaaagcc tagctttctt gttataatgg ataagatgga
     6181 ggcgttatgg cactaaaaaa agcaagccta gcttgtgcgg tttgtggttc gagaaactat
     6241 tcaatcaaga tcagcggaaa ccccaagcct acacgactag aagtaaataa attttgtaag
     6301 cattgtggca agtacactac acacagagaa acgagatagg agagagcgat gcgttttatt
     6361 ggagatattt ttagacttct taaagacaca acatggccaa ctcgcaagga aagctggaga
     6421 gattttcgtt ctatcatgga atacacagct ttctttgtag taattattta catttttgac
     6481 cagttgattg tttcaggttt gattcgattt attaacattt tttagaagat tagtggagtt
     6541 aattacacta gaaatcttct atttatgaaa ggaaatatca tggatagttt tgataaaggg
     6601 tggtttgttt tacaaactta ttctggttat gaaaataagg tgaaagaaaa tctattacaa
     6661 cgtgcacaaa cctacaatat gttggataat attctacgcg ttgaaattcc aacacaaaca
     6721 gtgcaagttg aaaaaaatgg aaagagaaaa gaagtagaag aaaatcgctt tccaggttat
     6781 gttcttgtag aaatggtcat gacagatgaa gcttggtttg ttgttcgaaa cacaccaaat
     6841 gttacaggat ttgtcggatc acacgggaac agatcaaaac caactccatt attggaacaa
     6901 gaaattcgcg acattttggt atctatggga caaactgttc aagaatttga tttcgatgtt
     6961 gagattggtc aaactgtacg tattattgat ggtgcttttg cagactacac tggtaagatt
     7021 acagaaattg ataataacaa agtgaaaatg attatctcta tgtttggtaa tgacacagtt
     7081 gcagaagtaa atctaaacca aatcgcagaa t
//
LOCUS       DAVAGB010000071         7075 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVAGB010000071 DAVAGB010000000
VERSION     DAVAGB010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7075
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.072"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(80..310)
                     /locus_tag="VQO19_001966"
     CDS             complement(80..310)
                     /locus_tag="VQO19_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350178.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(328..969)
                     /locus_tag="VQO19_001967"
     CDS             complement(328..969)
                     /locus_tag="VQO19_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET1350179.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(981..1661)
                     /locus_tag="VQO19_001968"
     CDS             complement(981..1661)
                     /locus_tag="VQO19_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HET1350180.1"
                     /translation="MGMFVGMFKARVESHEIILDVKALMPWISAICLLIGFISMFLTF
                     NFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNITGVAIPLAIFISLSEV
                     IILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFATPKDVLNYINSYDEG
                     ERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQLLAFLLVGAIHVYINVMQL
                     PMVKRYFK"
     gene            complement(1717..1914)
                     /locus_tag="VQO19_001969"
     CDS             complement(1717..1914)
                     /locus_tag="VQO19_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350181.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            complement(1914..2120)
                     /locus_tag="VQO19_001970"
     CDS             complement(1914..2120)
                     /locus_tag="VQO19_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET1350182.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(2130..2444)
                     /locus_tag="VQO19_001971"
     CDS             complement(2130..2444)
                     /locus_tag="VQO19_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350183.1"
                     /translation="MWVLVFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(2759..2839)
                     /locus_tag="VQO19_001972"
                     /pseudo
     CDS             complement(2759..2839)
                     /locus_tag="VQO19_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(2830..4119)
                     /locus_tag="VQO19_001973"
     CDS             complement(2830..4119)
                     /locus_tag="VQO19_001973"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HET1350184.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(4197..5444)
                     /locus_tag="VQO19_001974"
     CDS             complement(4197..5444)
                     /locus_tag="VQO19_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HET1350185.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSAFILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNAYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(5637..6488)
                     /gene="rgg"
                     /locus_tag="VQO19_001975"
     CDS             complement(5637..6488)
                     /gene="rgg"
                     /locus_tag="VQO19_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HET1350186.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATRGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEELLFLARGFQYDTDSELRKEITDVLKPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVDLTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            6612..6953
                     /locus_tag="VQO19_001976"
     CDS             6612..6953
                     /locus_tag="VQO19_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET1350187.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
BASE COUNT         2286 a         1480 c         1299 g         2010 t
ORIGIN      
        1 cctgcggcta gcttcctagt ttgctctttg attttcattg agtataatac aaaaatccga
       61 tgaacttcac cggactcttt tattttgaat ttttgcctgc tttacgcttt tcagcgattt
      121 cggctgcctt tcgaggcaag acaatttccg ttatgtaagc cgtcccaaaa cgcagtacac
      181 ctgcaatagg agcaaagaca actgctagat agttatagaa gaaatcgcct ttgaaggcat
      241 aagctagcgc tccaatgatg aaaaatagaa cgactgcctg aatcactgct aataaaatta
      301 ctcgtttcat gtgacctcct gactctatta tagcatgaga atcatcaaaa agccgactaa
      361 attattcaaa gcgtgaagag aaatactgta gaccagacct tttctgctaa tgtaagccaa
      421 acccaaacta aaaccaaggc taaaatagac aaaaaattgt tgcacatcac ctggaaaatg
      481 aatcaaggca aatagaagac tagataccag aagaaaaatc agggttcgtt tactattgtc
      541 ctgcttagga aagagatagc gtgctaacat ccctctaaaa acaatctctt ccgtcaaagg
      601 agcaaaaata accacagcaa agaatgagaa aagtggttga gacaaggtca agtctgtcgc
      661 tatttgctga tttactgaag gatcatctgg caagaagaat tgaacgacca gagataagaa
      721 ccaaaccaag acaggaagcc aaataaatcg attaaagccg ctcttctcaa tatgaacagg
      781 agccttctga taccatttgt aaatgccgta cacatatact ccagccaagg ccacatagag
      841 tagagtaaca gcatagggtg aagcgcctaa agcaagcgac gcagtcgcga gcccctgaat
      901 aaagccatag ataaataaaa aggatagaag ggctagaaga atccagccaa ggtttttaag
      961 taatttcata aataactcct ttatttgaaa taacgtttta ccataggtaa ctgcatcaca
     1021 ttgatataaa catggatggc tcctacaagc aagaaagcta gtaactgaat ctctcctgtc
     1081 aagaaagaaa tgataataag aaaaatatat aaggctggta agacatattg gtgtaattgg
     1141 aataaaattc gaaaactctg ttccaaatta gcctgacgct ccccttcatc ataagaattt
     1201 atatagttca agacatcctt tggtgtagcg aaaaattcca aatcaaactg acgaacaatc
     1261 gcaatggttt taaaaagaga tttttgagcg actaagaata ccacaaagag taagaaagaa
     1321 aggaaaaatg tttgagggtt tgtatgcaat ataatcacct cacttaatga aataaaaata
     1381 gccaatggaa tcgctacacc tgtaatatta aaagcaatgg ttccaaactc aagattccga
     1441 tacatttgca cataataggt ttcattcaga tcgtcatcca tttcctcttg atacaaggaa
     1501 tgaaattttc tgcttttctt taagaaattg aaagtcaaaa acatactaat gaaacctatc
     1561 agtaaacaaa tagctgatat ccatggcatc aaggctttta catctaaaat aatttcgtgg
     1621 gattcgacac gtgccttaaa catccctaca aacatgccca agaccccccc aagacaatag
     1681 acatcaaaaa taacaatcta cgtttctttt tcatattcat tctccttttt cacttgctag
     1741 atttttggat ttcttttcaa tccattcaat tactgggatg agagcaaagt agacccaaac
     1801 aaattggtcg ctttgatagg gattaaacca gcttaggtcc atcccaatca gtagaaatac
     1861 gctgactaat aaagctatga ccactacata ataaatcact ttatacttgt tcatcactcg
     1921 tcctcctcca aacgaaatac cgattcgact gtttcgttga aaatttgaga tattttcagg
     1981 gcaatgataa tggatggggt gtactcatcc cgttctagta ggctaatggt ctgtctggaa
     2041 acccctgcca gtttggctag gtcggtttga ttgagaccat cgcgagctcg aagctctttt
     2101 agacgatttt ttagttgcat gttacacacc tactctccgt caaattcaac ggtttggata
     2161 tcttcaatac gttgcaactt gaatttttct tttcccgtat tatctacacg tcgtagcttt
     2221 acccattcct catcaacatc cacaacttcc cagttatctg gcccaatata cactcccgtt
     2281 ataattggtt cctttccaat catttcttgc aataatctcg acatttctgc gtttcctttc
     2341 tcttttcgct caagtttttt gattttattc tctagtttct tgattttttt agaattatta
     2401 gaataaaaga aaatcataaa tagtataaat actagtaccc acattataac tcctttctgc
     2461 ttcctatttc ttaacttgaa ttcattgtaa cacatctttt tctttttgac aagtatggtt
     2521 gtcaaaaagt ttatgatttt tgtcattttg caaaagaaaa aggtcaggag taagttcctg
     2581 accactttat ctatcattaa tactcttcga aaatctcttc aaaccacgtc agcttcacct
     2641 cgccgtaggt atggttactg acttcgtcag ttctatccac aacctcaaaa cagtattttg
     2701 agctgacttc gtcagtttca tctacaacct caaaaccatg ttttgagctg acttcgtcag
     2761 ttctatccat aacttcaaaa cagtgttttg agcaacctgc ggctagcttc ctagtttgct
     2821 ctttgatttt cattgagtat aaaatcctag tttttcaaag atttctgaga agttttggct
     2881 gattgtctca agtgacactt gcacttcttc tcgggtttgg ttgttcttga ccgtcacttg
     2941 tccgctttcg acttcgctct ctcctagggt gatgagggtc ttagccgcaa agacatctgc
     3001 tgacttgaac tgagctttga gcttacggtt gaggtaatca cgctctgctt tgaaaccttg
     3061 ttggcgaaga gcttggacta gttctagggc tttgacattt gctccatcac ccaagactgc
     3121 gatatagaca tctagggcgt tttcgatagg gagggccacg ccttgttttt caaggatgag
     3181 aagcaggcgc tctacaccaa gcccaaaacc aaatccagca gtttcagggc ctccaaagta
     3241 agcaaccaaa ccatcgtagc gaccacccgc acagactgtc aagtcattgc cctcaatctc
     3301 tgtgataaac tcgaaaatgg tgtggttgta gtagtccaga ccacgcacca tattggtatc
     3361 gatgatgtaa tctactccaa gattttccaa catctgacgc acagcatcaa aatgagtttg
     3421 gctttcttca tcaagaaagt ccaagataga cggcgcattc tctactgcca ccttgtcttc
     3481 tttttcctta gagtccaaga cacgaagagg attttcctcc aagcgacgtt ggctatcctt
     3541 agacaaggtc tccttgagcg gtgtcaaata gtcaatcaag gcttgacggt aggctgcacg
     3601 gctctcagga tttccaagag tgttgaggtg caatttgaca ccttgaatac cgatttcctt
     3661 caaaaaatgg gctgccatag cgattgtttc cacatcggta gctggattgc tagagccaaa
     3721 acactcaaca ccaatctggt ggaattggcg caagcgccct gcctgtggac gctcataacg
     3781 gaacataggt cccatatagt agaacttgct tggcttttgc acttctgggg cgaagagttt
     3841 attttccaca taggaacgga caacgggcgc agttccttct ggacggaggg taatatgacg
     3901 gtcacccttg tcataaaaat cgtacatttc cttggttacg atatccgttg tatctccgac
     3961 agagcgactg ataacctcgt aatgctcaaa aataggcgtg cgcacttctg catagttata
     4021 gcgcttgaaa atctcacggg caaagccctc aacgtactgc cacttagcag actcagcagg
     4081 taaaatatcc tgcgttcctt ttggtttttg taatttcata gggaatcctc tttaaactta
     4141 atagtcttat tttaccacaa ataaagggat taaaacagtg agaaaaaaat taggatttag
     4201 atatcatttt tgagattaag aattgtcaaa aaaatagcta gcaaggaaag gccaacaaat
     4261 agcatccaag tcaactgtat attccatacg gctactagtg aaaaacaagc tgttcccaca
     4321 ggtatggata aggtaaacaa tagacctaaa aaattactag tacgagctag aacctctgga
     4381 gctagatttt tcatgagcat ggcactaatc tttggttgaa ctttaccaga cacatacaga
     4441 gtaaagaaga gaaatagcaa accaagcacg acttgattga ataaattagc caaaccaact
     4501 agactaagtc ctacagtcgc ccacatcatc aatctaggca aggactgctt cccaaaataa
     4561 gcattgcccg taaggctact gatgatgatt gctactaaaa cacagaattg attgataaat
     4621 agtgcctctg tataagaaaa attcaagaga gaatggctca aaaagaagat attataaatt
     4681 ccacccaaag cgccacccaa ggaattaata agcaagacag caaagagcat aaaaccaaag
     4741 tttttctgcc cacttttaag aaaaacgaga cgtaaatttc ggtaaattgt taggaactgg
     4801 tctttgatag aaagcttctc attttttaag ttttcaccat cagcagatga cattgacagg
     4861 ctcaatttgc tttttcctaa aaagagaata aaggctgata cgaggaaaaa gcaggcattg
     4921 attcccgcaa cgagagaaaa attgttgacc gatagagcta agagccagac tccgaaagct
     4981 tgaccaccaa tagctgaaat ataggtgatg aactgtgaaa aagaataagc ctccatcaga
     5041 tcatcttcag ctactttttc cttaataaga ggcatacgca ggccacctgc aaaatcactg
     5101 atgatatcac taatgacatt gatcaaacac aggctagaaa aggcaaagag actagcttgc
     5161 tgaacaacta gggctgctag aaaaaataga accgcctgaa acaaaccgct atagaccatc
     5221 catttgacct tgtccctcgt gtaatctgcc cgaatccctg caaaaactgt aaagagggtc
     5281 ggaagaatca tgacaatatt cgccatagca acagcaaaag atgcttgtga caaggtcgat
     5341 gcatagacga taaagaccag gttgaaaatc gaagcaccaa aagcattgaa gaagcgtgat
     5401 aaagtcaaaa ttctataagc tggatttcta aacaatagtt tcatagataa tctcccttct
     5461 tgttcgaacc tctatatgaa gtatgactat agtatagcac ttagaaattt gagagggaga
     5521 actcttgaat atatgcaaca aataaaatga gcaaaaagaa acgatagaac ttttgtaatg
     5581 acctgagaga gggcaatagt tctatcgctt caaatttttt cttggtttgc agatattcaa
     5641 cattcggtcg tatttctata gtattcggca gatttattac agccaagcat ctcaaaaata
     5701 cgaacagcat cctccatctt tttctggcct tccttgactc taccttgctt gctatcaagg
     5761 agaccttctg cccacagata aacaattcgg aaataggtct cattttcctt gtagaaatgc
     5821 tcttcgataa cacgtttaaa ataataggca ttggtaaatt cttcacactc aatactagct
     5881 aaaaagccgt tcaatagtat agtatgaaaa aggtttcgat tgccagacat ttccattaga
     5941 aaatcagatt tacgtaccat ttctcgtaca tatctagtaa aaagagaaac agataaaaat
     6001 ggagaactga ctgaaaataa attgagttca tagattcccc agatctcggt agaaaacaaa
     6061 taatcatgaa ggacttttcc ttcctctgct gttaagtcta ccctttcatc tatgctcttc
     6121 atataagact tgataataat ggcatttaga atatgtttct gtttgttgtg agaatgggca
     6181 tgcttttgat actccctgcg atataagtcc tcaagaggtg ctatattctt tggtttcaag
     6241 acatctgtaa tttcttttct caactcagaa tctgtatcat actggaaacc tctcgccaga
     6301 aagaggagct cctccacact ggcagatata ttttccagag caaatagaaa cttttccacc
     6361 gaaagctcac tctgacctgt ttcaaaacgg gacaacatag acggcgaaaa ttgtcctctg
     6421 gttgcttgtc tcagtgagat atttcttgac tctcgtaatt gtctaaagac ttttccaatc
     6481 tgctccatag acttcccctt gattccgtat tttcttcatt ttatcatatt tttcagaaaa
     6541 ttcatcaaaa acttgccaaa ttgtcagaat tatgagaaaa tagaggatat ttatcacgtg
     6601 gagggactgc tatgagagac gatatcaaaa tcaatgaccg tgctttggcc ttgcaagacc
     6661 aaattatcga aaaactagag aaagtttttg atacagatgt ggaattggat gtttacaatc
     6721 taggtctgat ttatgaaatc aatctggatg aaacggggct ctgcaagatt gtcatgacct
     6781 tcaccgatac tgcctgtgat tgcgccgaaa gcctgcctat tgaaatcgtg gcaggtctga
     6841 aacaaatcga gggtatcaaa gatatcaagg ttgaagttac ctggtcgcct gcttggaaaa
     6901 tcacacgaat cagtcgctat ggccgtattg cccttggact accacctcgt taagcaggcc
     6961 aatcactttt aaagatgaaa aaagcaagcc gaaaatggct tgctttttga tactcaatga
     7021 aaatcaaagg gcaaactaga aaactagccg caggttgctc aaaacactgt tttga
//
LOCUS       DAVAGB010000072         6831 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVAGB010000072 DAVAGB010000000
VERSION     DAVAGB010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6831
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.073"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(<1..896)
                     /gene="whiA"
                     /locus_tag="VQO19_001977"
     CDS             complement(<1..896)
                     /gene="whiA"
                     /locus_tag="VQO19_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HET1350188.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINK"
     gene            complement(893..1870)
                     /locus_tag="VQO19_001978"
     CDS             complement(893..1870)
                     /locus_tag="VQO19_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HET1350189.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            complement(1867..2757)
                     /gene="rapZ"
                     /locus_tag="VQO19_001979"
     CDS             complement(1867..2757)
                     /gene="rapZ"
                     /locus_tag="VQO19_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HET1350190.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMNQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            complement(2809..3189)
                     /locus_tag="VQO19_001980"
     CDS             complement(2809..3189)
                     /locus_tag="VQO19_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HET1350191.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            complement(3200..3787)
                     /locus_tag="VQO19_001981"
     CDS             complement(3200..3787)
                     /locus_tag="VQO19_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HET1350192.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            complement(3796..5028)
                     /gene="clpX"
                     /locus_tag="VQO19_001982"
     CDS             complement(3796..5028)
                     /gene="clpX"
                     /locus_tag="VQO19_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HET1350193.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            complement(5060..5230)
                     /locus_tag="VQO19_001983"
     CDS             complement(5060..5230)
                     /locus_tag="VQO19_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350194.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            complement(5230..5736)
                     /locus_tag="VQO19_001984"
     CDS             complement(5230..5736)
                     /locus_tag="VQO19_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HET1350195.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            complement(5866..6384)
                     /locus_tag="VQO19_001985"
     CDS             complement(5866..6384)
                     /locus_tag="VQO19_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HET1350196.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
BASE COUNT         1925 a         1597 c         1313 g         1996 t
ORIGIN      
        1 atcttattga tttttctgag tctgtgattg acaccacttt tggtcagagg ggtgctgaga
       61 ctatctgcta actgctggat agagtagtct gggtgctgaa tcctcagttg cgccacttcc
      121 tgcaaatcta ctggcaaatt ttctaagccc atgatatctt tgattttact gatattgtta
      181 atggtcttca tgctggcaga aactgtccga gcgatattag ctgtctcggc attattagcc
      241 cgattgaggt cgttacgggt ttctcgcaaa atcttaaccc gctcaaaatc atcacgtgcc
      301 tgcatggctc cgattactat caagaagtcc ataatgtctt ctgctcgctg gagataggtc
      361 acagccccct tcttgcgctc aagcaccttg gcatccagta aaaactgttg gagaagggag
      421 gcaattcctt gcgcgtggtc cagataaaca gaactgattt ccaactggta cttgcctgac
      481 tcagggtcac gaatgctccc atttgccaag aaagcgccac agagataggc acgacctgct
      541 tcctcatccg ataaaatcgc ctcatcaata cctgtttcca ggccaaagaa agagtctgcc
      601 aagtgcaaat cacttaacaa atcctgcacc ttttcatctg taaaaacggt atagacgcga
      661 ttcttgcgaa gattgctccg ttggtggtga cgaatttcag atttgatttc atagaaatga
      721 agaaaggact catagaggtg acgggccagt ttggcatttt ctgtcacaac tgacaaagtc
      781 aagcccgaag tcgagagacc gatgctacca gacattttga taatggcaga taattcatgc
      841 cagctcagat ggtgttggcc caggatttct tcttttactg ctactgtgaa actcattttt
      901 tcacctgtat aatgcgcatc aactcgtcca caatcaaatc tccatcgtgg aaggcaccgc
      961 cattttccag acgaaggaag ttagatgaaa tcacgcgcga aacttgctta caaagaccta
     1021 caaaatcgtg ttccacttgc actaagtatt catcaaaacg gttggaattc atgtattcct
     1081 gaggcacttt ttcaatattc accaagacag tgtcgataaa agggcgacca aggtgacgat
     1141 gcaagacttc cacgtggtcg ctatctgtaa agtgttccgt ctccccacgt tgggtcatga
     1201 tattgcagac ataggcaatt tctgccttag tttccaaaag agcccgccca atttccttaa
     1261 tcacgatatt gggcaaaata gaggtaaaga gggaacctgg ccctaggaca atcatgtcac
     1321 tttcaaggat ggtctgcact actcgacggc tggccagagg cgtatcatcg tttagggcat
     1381 tggtcacata gacattgtca attatgcctc gatggtctac aatatgactc tctccagcca
     1441 cttctgtccc atcctgaaag actgcatgaa gggtcaaagg atggtcactg gaaggataaa
     1501 ttttccctgt tgtatggaaa aatttgctca ataactgcat ggcattatag gttgaaccct
     1561 gcatttctga caagccagca atgatgagat ttcccaatgg atggccagca aaggctccgg
     1621 catcctcaga gaaccgatac tgaaagacct tctcataaaa cttaggcata tccgacatgg
     1681 ccacaaggac attacgaaga tcacctggcg gtgtcaactg ttgcatattt tttcggagtt
     1741 cacctgaaga accaccatca tctgccaccg tcacgatagc tgcgatttcc acatcttttt
     1801 cccgcagact ttttagaatg acgggaattc cagtccctcc accaatcacc gttatctttg
     1861 gttttctcat gaacggttta ccgtttcctt tctgcggtct ttgtcgcgat gcccttcatt
     1921 aacagaccaa ttcttggata agtcctgcgc caagcgttta gcaaatgcca cactacggtg
     1981 ttgtccaccc gtacatccca tagcaatggt caaaacggac ttaccttcct tttggtaact
     2041 tggcagaatc ggctcaatca aggccaataa atgttgataa aagtcttctg actcaggatg
     2101 gttcatgaca taatcataaa caggttcatc cacacccgtt tggtttctca gttctggtag
     2161 ataataggga tttggcaaga aacggacatc aaagaccaag tccgcatcaa tcgggattcc
     2221 atacttaaat ccgaaagaca tgacttcgat acggaaagac tgggcttgtt cttggtctga
     2281 aaactgctct gcaagggttt tgcgcagttc acgtggagtg agttcagtcg tatccaccac
     2341 attttggttc atatttttca aaggtgccaa gagttcacgt tccaacttga ttccatctaa
     2401 aatacgaccg tctgctgcta gtgggtgact ccgtctggtt tccttgtaac gagcgaccaa
     2461 ttccttatca gccgcatcca aaaagaggat tttgaaatcc aaaccatctt gattttccaa
     2521 ctcatccaaa acagcttgaa tctctgaaaa gaaagaacgg ctacgcatat ccactaccaa
     2581 agccaactta ggattatctt ccttaatttc aaccagctgc aaaaacttag gcaagagagc
     2641 tggcggcata ttatcaatgg tgaaataacc tagatcctcg aaggactgaa tggctacagt
     2701 tttccctgcg ccactcatcc ctgtcacaat caccaagtga agttgtttct ttgtcatctt
     2761 tttctcctta tatcaaaaga agtttggcaa caccaaactt caactagctt atccaatctc
     2821 tgcgatgact tcaatttcga cttttacatc acgaggaaga cgagctacct ccacagctga
     2881 acgagctggg aattcctctt tgaaggccgt ttggtaaacc tcattaaaag gaacaaagtc
     2941 gttcatatcg ctcaagaagc aagttgtttt gacaacatgg tcaaagtctg ttcctgcttc
     3001 tgccaaaata gcaccgatgt ttttcaagac ttgctctgtc tgttcttgga tattctctcc
     3061 tacaatttcc ccagtttcag gggatagggg aacttgaccg ctagcaaaca aaaggttgcc
     3121 aacgattttt ccttgaacat agggtccgat agcctttggg gccttatctg tatgaattgt
     3181 ttttgccatt ttcttttcct cacaattttt ctaagattgc atcccaagcc tcatccatcc
     3241 ctgccttgct gacagatgaa aagaggatga aatcgtcact cgggtcaaag tttaatttct
     3301 ttttgattgc tgattcatgc ttgttccatt taccacgagg aatcttgtcc gccttggtcg
     3361 ccacaatgat gactggaatc tcataatact tgagaaattc gtacatctgc acatcatctg
     3421 ctgacgggtc atgacgaagg tcaactagac tgacaaccgc acggagattt tcccgagtcg
     3481 ttaagtactc ctcaatcatg cacccccact tttcacgttc ctttttagaa acacgagcat
     3541 agccataacc aggcacatcc acaaagcgca tcttgtcatc aatgttaaaa aagttcagga
     3601 gctgggtttt accaggtttt cctgatgtac gggcgagatt cttacggttc aacatagtgt
     3661 tgataaagct ggatttacca acatttgaac gccctgctag ggcaatctct ggcagttcat
     3721 cctgcggata gtgggactta ttagctgcac tgagcaagat ttcagcattg tgtgtattaa
     3781 gttccatagt cacctctagg ctgtttctag gatcggttta tccgttccat cgacagtttc
     3841 tttagtgatg cgaaccaatt tcacattttc ctgactcggc acctcaaaca taacatctag
     3901 catggtttct tcgatgatgg agcgaagtcc acgcgcccct gtcttccgtt cgattgcttt
     3961 attagcaatc tcttgaaggg cttcgtcgtc aaattccaac tcaacatcat cataagaaag
     4021 caaggtttgg tattgtttca ccaaggcatt tcttggctct ttcaagatgc gaaccaagtc
     4081 atcaacggtc aattgctcaa gagccgcaaa aacaggcaag cgtccaatca actcagggat
     4141 aataccaaat ttttgaatgt cttcagcgat gatttcttgc atgtatgagc tgttttcgtc
     4201 aatcgcctta ttgttttgac caaatccgat gactttttca cccagacgtt gtttgacaat
     4261 ttcttcaata ccatcaaaag caccacccac gatgaagagg atattttttg tatccacttg
     4321 aatcatctct tgttgtggat gtttgcgtcc accttgaggc ggtacgctag caacagttcc
     4381 ctcgataatc ttgagaaggg cttgttgcac cccttcacca gaaacatcac gtgtgataga
     4441 cacattctca ctcttcttgg caatcttgtc aatttcatcc acatagataa tgccacgctc
     4501 tgcacgttcg atgttaaagt cagcaacctg caagagtttg aggaggatat tttccacatc
     4561 ctcacccaca taaccagcct ccgtcagagc tgtcgcatcc gcaatagcaa aaggtacatt
     4621 caagctctta gccaaggtct gggcaaggaa agttttccct gaaccagttg ggccaatcat
     4681 caaaatgttt gacttctgca aatccacatc ttctgactct tcgcgtgtat cgtggaaatt
     4741 gatgcgtttg tagtggttat aaaccgccac tgccaaggca cgcttggcac gatcttgacc
     4801 aattacatag tggttcaaga tatggaggag ttcaattggt tttggcacct cagacaagtc
     4861 tgccaagact tcctcaacca attcttctcg aatgatttcc tgagctaact ccacgcattc
     4921 attacaaata aaagcattgt tgccagcaat tattttttgt acttcttctt ggtttttgcc
     4981 acaaaatgag caataaacca tcatatcatt ttttctattt gtagacatga tttccttcca
     5041 ttctatactg tcattctatc taaaataagg tcatgtaaaa agcatgaata ctattgacca
     5101 gattggtaaa ggcatttaac caaaggagga tagaaagccc gtaacgcttt ttacgaaaag
     5161 cttgtgctcc tgccagaaag cagatgaaac acagaaaagc cgtgaataga ccaaataaac
     5221 tccgttccat tagacttcct ttctcttgcg gtattggatg gtaaaatcat aaggattctt
     5281 ctcatctttg gcgtaaaatt tgcttgaaac tgtctcaaaa agagacaagt caagttcttc
     5341 agggaaatag gtatctcctt ccacccgagc atgaatgtga gtgacaatca cttcatcaag
     5401 gtaaggttca aaagcctgaa aaatttgctt cccaccgata atgtagagat tcttttcttg
     5461 agcctgatac cagtcaagaa cagactggac gtcctgaaaa gtagcaaccc catctatctt
     5521 ttcttccgga ttacgcgtca aaatcaaggt ttcccgtttt ggaagcaagc gacgccccat
     5581 cccatcaaag gtcacacgcc ccatcaagat agcatgattc agagttgttt ctttaaagtg
     5641 ctgcaattct gctggcaaat gccaaggcag acgattttcc ttaccaatca caccctcttc
     5701 atcctgggcc caaatagcta cgattttctt agtcatgctt ccatcctttt cactgatagt
     5761 actattttat caaaaaactc aaaaaaagac tggtttggaa tagcttacaa aatagaaaaa
     5821 atctgtaaga aatttcctac agatttatct atgtttcctt atttcttaca aaccaggtgc
     5881 ttgtccaagt tcggctgcaa gcatccaaat tgttttatct gtttcagttt tagcgcctgc
     5941 aaagataccg tttgtcacat cgtcaccttc ttcatcagtg acatccaaac ctttttggaa
     6001 aagttctgac aagtaacggt agataacaag aacacgttcc aagctttctt caacattacg
     6061 gtattcacca gcttcttctt cgatttcact attttgaagg aactctgtca atgtagagaa
     6121 tgggcttcca ccgagtgtaa tcaagcgttc gctgatttca tccaattgac cgtcaagagc
     6181 ttccatgtac tcatccattt ttggatgcca tacaaggaaa ccacgaccat gcatatacca
     6241 gtgcacttgg tgcaaagcaa cgtgagctac atacaaatca gcaacagctt ggttcaagac
     6301 ttcctttgtt tttgccaatg ctactggcgc tgcttttgtc aatgatgtta cgtcttttac
     6361 tgcttctttt ttcaattcta ccattttctt tacctcattc attatttttt gtaaccactt
     6421 cttaatgatt actaccttag tatactacta aggaaaacca atagcaagac aaagaactta
     6481 tatgagaaaa gttgcaatag actgataatt taagaattct ttagaagaca aaaaagaggg
     6541 ttggatgctt atagtcaatg gaaatccatc agcaaactag gaaactaaac ccagcttgac
     6601 caaagcacaa gttttgaggt cgcaggtaga actgaccaag ctgatgtggt ttgaagaaat
     6661 tccccaatac tataatagat tgaaataaga tgaaaccaag tcgattagga aaggtaaatg
     6721 aatttctaaa atgttttacc aatcacaagg tctttgtcta tattcaatct actatataag
     6781 cttcatttcc gagcaagatc ttgaatttac tcgaggatga actatcataa a
//
LOCUS       DAVAGB010000073         6696 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVAGB010000073 DAVAGB010000000
VERSION     DAVAGB010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6696
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.074"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            88..1266
                     /locus_tag="VQO19_001986"
     CDS             88..1266
                     /locus_tag="VQO19_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350197.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDCQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKNGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            1475..>6696
                     /locus_tag="VQO19_001987"
     CDS             1475..>6696
                     /locus_tag="VQO19_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET1350198.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKG
                     EPAVQPELPEAVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQGAENPVQPAEESTTNSEKVSPDTSSENTGEVSNKPSDS
                     TTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNS
                     GKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEPSNGN
                     STEDVSTKSNTSNSNGNEEIKQENELDPDKKVEDPEKTLELRNVSDLELYSLSNGTYK
                     QHISLEQVPSNPNSYFVKVKSSSFKDVYLPVASISEERKNDKILYKITAKVEKLQQEI
                     ESRYKDNFTFYLAKKGTEETTNFTSFSNLVKAINQNLSGTYHLGASLNANEVELSTDD
                     KSYIKGTFTGQLIGEKDGKHYAIYNLKKPLFENLSGATVEKLSLKNVAISGKNDIGSL
                     ANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESSFKGRIVNTYETTDSYNI
                     GGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLVDRDAQIQDSYAEGDINN
                     VKHFGRVAGVAGNLWDRTSGDVRHAGSLTNVLSDVNVTNGNAITGYHYTGMKVANTFS
                     SKANRVFNVTLEKNEVVSKESFEERGTMLDASQIASKKAEINLITPPIVEPLSTSGKK
                     DSDFSKIAHYQANRALVYKNIEKLLPFYNKATIVKYGNLVKENSILYQKELLSAVMMK
                     DDQVITDIISNKQTANKLLLHYKDHSSEKFDLRYQADFANLAEYSIGDSGLLYTPNQF
                     LYHQDSIINQVLPELNRVNYQSDAVRNTLGISPEVKLTELYLEEQFTKTKEHLAENLK
                     KLLSSDAGLVTDNEVMTGYIIDKIKRNKEALLLGMSYLERWYNFSYGQVNVKDLVMYH
                     PDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYAISLASHHGTTDLFSTLENYRKV
                     FLPDKTNNDWFKSQTKAYIVEEKSNIEEVKTKQGLVGTKYSIGVYDRITSATWKYRNM
                     VLPLLTLPERSVFVISTISSLGFGAYDRYRNKEHQANGDLNSFVEKSAHETAERQRDH
                     YDYWYRILDEKGREKLYRNILLYDAYKFGTNHTEGKATEVADFDSPNPAMKHFFGPVG
                     NKVGHNGHGAYATGDAVYYMGYRMLDKDGAITYTHEMTHNSDQDIYLGGYGRRSGLGP
                     EFFAKGLLQAPDQPSDATITINSILKHSKSDSKEGERLQVLDPTTRFKDATDLQKYVH
                     NMFDVVYMLEYLEG"
BASE COUNT         2452 a         1179 c         1341 g         1724 t
ORIGIN      
        1 acaacctcaa aacagtgttt tgagctgact gcgactagct ttctagtttg ctctttgatt
       61 tttattgagt attagaaagg agacctcatg acacttccag ttagaaaatc cctgcacgat
      121 gcagttttac aggcttcgaa agcggatact tgggaacaag ctaccaagga atggaatgaa
      181 gtttccttga tttttaacgg tatcggccgt agcaattgtg tctgtggaaa tgccatcaaa
      241 tacgcttatg aactctttaa cggtgtcaca ggccaacgcc tctttccaat tggtagcgac
      301 tgtgttcgtc attttcatcg attgtccctt gaccagcaat tggaagagga agaaaaactg
      361 ctcagaaagg ttgaaaatct aaccagaaaa gctcagaaaa aggaaaaaat caaggtcaat
      421 aaaagtgact ttgacgagcg acttctaaaa tggctctggg aaaaaggtgt tttcaaaccc
      481 aatcgtggca atcaatttgc gcctgagaga gactgccagc ttttcctaga agtctttcag
      541 ggaggaagtt ggaccaaggc ggaaccaaag aaaaaggctc ggatggaaga agtccttgaa
      601 aagtgtatca aacccttttt acttgggaaa tcggatgacc aactctacct tgtcaagcta
      661 ggcaaggaga aaattgacta cgaacaagaa ctccgtatcc aggcagagaa agaacgcaag
      721 aagagggata aaatcgccaa gcaatatgca gacaatctgg ttctagccat gggacccgca
      781 gagcgtgctt atcaagatta ctttggcttt acagagaccc tgactcaaga agaacgcaag
      841 tgggaaaaaa ttctttttgg taaaaataga gcagaacggg ctatcaaggc caaacaatac
      901 caaaaagagc tggaaaaaga ccaacgaatt gccagtcagg atccaattga aagaaaacag
      961 aagcagactt ggctcctcaa ttcctatttt cgtgagcttc ctgaagaaaa agctcgattt
     1021 tctaggctct tattagaata tcgaaaaaat ggtgaagtac ccttttcaac tgaatacctg
     1081 tcagatcatc tcatcgactt tttctataaa atgaaagcct ttgaatttga aatcgcacca
     1141 gaacaagtcc gagattttct aaaaaaaagc ctgcaggaag accatcgctc atcagcacaa
     1201 ggaagctgga tagaaggaat tctcctcaac tgcctcaaac catttttaga acgattagtg
     1261 atatgagtaa cacctaccgt gtaaatttca tggtaggtgt tattgtacct caaaataata
     1321 taaaacaaag tatgaaagcg catctcaatt ttaagacttt tttgtaaatt aagagtataa
     1381 ttaaggtata ctgccttttc tatagataat agataataca ctaatataat aaaggtcttt
     1441 gtaacatata taaattttat ttcaaggagg aataatggaa aagtattttg gtgaaaaaca
     1501 agagcgtttt tcatttagaa aattatcagt aggacttgta tctgcaacga tttcaagttt
     1561 attttttatg tctgtattag ctagttcatc tgtggatgct caagaaactg cgggagttca
     1621 ctataaatat gtggcagatt cagagctatc atcagaagaa aagaagcagc ttgtctatga
     1681 tattccgaca tacgtggaga atgatgatga aacttattat cttgtttata agttaaattc
     1741 tcaaaatcaa ctggcggaat taccaaatac tggaagcaag aatgagaggc aagccctagt
     1801 tgctggtgct agcttagctg ctctgggaat tttaattttt gctgtttcca agaaaaaggt
     1861 taagaataaa acggtattac atttagtatt ggttgcggga ataggaaatg gtgtcttagt
     1921 ttcagtccat gctttagaaa atcatctttt gctaaattac aatacggact atgaattgac
     1981 ctctggagaa aaattacctc ttcctaaaga gatttcaggt tacacttata ttggatatat
     2041 caaagaggga aaaacgactt ctgattttga agtaagtaat caagaaaaat cagcagccac
     2101 tcctacaaaa caacaaaagg tggattataa tgttacacca aattttgtag accatccatc
     2161 aacagtacaa gctattcagg aacaaacacc tgtttcttca actaagccga cagaagttca
     2221 agtagttgaa aaacctttct ctactgaatt aatcaatcca agaaaagaag agaaacaatc
     2281 ttcagattct caagaacaat tagccgaaca taagaatcta gaaacgaaga aagaggagaa
     2341 gatttctcca aaagaaaaga ctggggtaaa tacattaaat ccacaggatg aagttttatc
     2401 aggtcaattg aacaaacctg aactcttata tcgtgaggaa actatagaga caaaaataga
     2461 ttttcaagaa gaaattcaag aaaatcctga tttagctgaa ggaactgtaa gagtaaaaca
     2521 agaaggtaaa ttaggtaaga aagttgaaat cgtcagaata ttctctgtaa acaaggaaga
     2581 agtttcgcga gaaattgttt caacttcaac gactgcgcct agtccaagaa tagtcgaaaa
     2641 aggtactaaa aaaactcaag ttataaagga acaacctgag actggtgtag aacataagga
     2701 cgtacagtct ggagctattg ttgaacccgc aattcagcct gagttgcccg aagctgtagt
     2761 aagtgacaaa ggcgaaccag aagttcaacc tacattaccc gaagcagttg tgaccgacaa
     2821 aggtgagccc gctgtccaac ctgaattacc cgaagcagtt gtaagtgata aaggtgaacc
     2881 agagcaggta gcaccattgc cagaatataa ggggaatatt gagcaagtaa aacctgaaac
     2941 tccggttgag aagaccaaag aacagggtcc agaaaaaacg gaagaagttc cagtaaaacc
     3001 aacagaagaa acaccagtaa atccaaatga aggtactaca gaaggaacct caattcaagg
     3061 agcagaaaat ccagttcaac ctgcagaaga atcaacaacg aattcagaga aagtatcacc
     3121 agatacatct agcgaaaata ctggggaagt atccaataaa cctagtgatt cgacaacctc
     3181 agttggagaa tcaaataaac cagaacataa tgactctaaa aatgaaaatt cagaaaaaac
     3241 tgtagaagaa gttccggtaa atccaaatga aggcacagta gaagggacct caaatcaaga
     3301 aacagaaaaa ccagttcaac ctgcagaaga aacacaaaca aactctggga aaatagctaa
     3361 cgaaaatact ggagaagtat ccaataaacc tagtgattca aaaccaccag ttgaagaatc
     3421 aaatcaacca gaaaaaaacg gaactgcaac aaaaccagaa aattcaggta atacaacatc
     3481 agagaatgga caaacagaac cagaaccatc aaacggaaat tcaactgagg atgtttcaac
     3541 caaatcaaac acatccaatt caaatggaaa cgaagaaatt aaacaagaaa atgaactaga
     3601 ccccgataaa aaggtagaag atccagagaa aacacttgaa ttaagaaatg tttccgacct
     3661 agagttatac agtttgtcaa atggtactta taaacaacac atttcgttag agcaagttcc
     3721 aagcaatcca aatagctact ttgttaaagt gaaatcttct tcattcaaag atgtatacct
     3781 accagtagca tcaatatcag aggaaagaaa aaatgataaa atcctttata aaatcacagc
     3841 aaaagtagag aagcttcagc aggagataga aagcagatat aaagataatt ttaccttcta
     3901 tctagctaag aagggaacag aagaaacaac aaactttact tcctttagta atctggtcaa
     3961 agctataaac caaaatctct ctggaaccta tcatttagga gctagcctga atgctaacga
     4021 agtggagctt agtactgatg ataaatccta tatcaaggga acctttactg gtcagttgat
     4081 tggtgaaaaa gatggtaagc attatgctat ttacaacttg aaaaagcctc tttttgaaaa
     4141 cttgagtggt gctacagtag aaaaactgag tctaaaaaat gttgctattt cagggaaaaa
     4201 tgatattggt tcactggcaa atgaagctac gaatggcaca aagattaaac aagttcatgt
     4261 tgatggtgtt cttgctggag aacgtggtgt cggtggtttg ttggctaagg cagaccaatc
     4321 aagcatcgca gagagcagtt tcaagggaag aattgtcaat acctatgaaa cgactgattc
     4381 ctacaatatt ggcggtctgg tcggtcattt aacaggaaaa aatgcgtcta ttgctaaatc
     4441 caaagcgaca gtaaccattt cgtcaaacac caataggtca gatcagactg tcggtggtct
     4501 tgcaggtcta gtagaccgag atgcacagat ccaagatagc tatgctgaag gtgatatcaa
     4561 caatgtcaag cactttggta gagtcgctgg agtggcaggc aatttgtggg atcgaacttc
     4621 tggtgatgtt aggcatgctg gaagtttgac caatgttctc agcgatgtta atgtaacaaa
     4681 cggaaatgcc atcactggat accactatac aggaatgaag gtagctaata catttagtag
     4741 taaggctaat agagttttca atgtcacttt agagaagaat gaggtcgtca gcaaagaatc
     4801 cttcgaggaa agaggaacaa tgctagatgc ttctcaaatt gcaagcaaaa aagcagaaat
     4861 caatcttatc actccaccaa tagtggaacc cctctcaaca agcggtaaga aagacagtga
     4921 tttttctaag atagcccatt atcaagccaa ccgtgctttg gtttataaga acattgaaaa
     4981 attgttacct ttctataaca aggcgaccat cgtgaaatac ggaaacctgg ttaaggagaa
     5041 cagtatctta tatcaaaaag aactcttgtc tgcagttatg atgaaggatg accaagtaat
     5101 cacagatatt atttccaaca aacagactgc aaacaaactc ttgcttcact acaaggacca
     5161 ttcatctgaa aagtttgatc tcaggtacca ggctgatttt gccaatttgg cagaatatag
     5221 cattggagat agtgggcttc tctatacgcc aaatcaattc ttgtatcatc aagattctat
     5281 tattaaccaa gtgctgcctg aattgaatcg agtaaattat caatcagatg ctgttagaaa
     5341 tacacttgga atttcaccag aagtgaagct aacggagtta tatcttgaag aacaatttac
     5401 caaaacgaaa gagcatctag cagagaactt gaaaaaactt ttatcatctg atgcaggttt
     5461 agtaacagac aatgaagtta tgacaggata tataatagat aaaattaaac ggaataagga
     5521 agccttactt cttggaatga gttatttaga acgttggtat aactttagct atggtcaagt
     5581 gaatgtcaaa gacctagtta tgtatcatcc ggacttcttt ggtaaaggaa atacttcacc
     5641 attagatact ctgattgagt taggtaaatc tggctttaac aatcttcttg ctaaaaacaa
     5701 tgtcgatact tatgctatca gccttgccag ccatcatgga acgacagatt tgtttagcac
     5761 gttggaaaat taccgaaaag tctttctacc agataaaacc aataatgact ggtttaaatc
     5821 acagactaag gcttacattg tcgaagaaaa atccaatatc gaagaggtga aaacgaagca
     5881 aggactagtt ggcactaagt attctattgg tgtctatgac cgtatcacta gtgccacatg
     5941 gaaataccgt aatatggtac tacctctact taccttgcca gaaagatccg tatttgtcat
     6001 ttcaaccata tctagtctag gttttggtgc ttatgatcgc tatcgtaata aagaacatca
     6061 agcaaatggt gatcttaata gctttgttga aaagagtgct cacgaaacag cagagcgtca
     6121 acgagatcac tatgattatt ggtatcgtat tctagatgaa aaagggcgtg aaaagcttta
     6181 tcgaaatatc ttgctttatg atgcctataa atttggaact aatcatactg aaggaaaggc
     6241 tacagaagta gcagattttg atagtccaaa tcctgcaatg aaacatttct ttggacctgt
     6301 tggaaataag gttggacata atggacatgg tgcttatgct acaggggatg cagtatatta
     6361 tatggggtat cgcatgctag ataaggatgg agctattacg tatactcatg agatgacgca
     6421 taattcagat caagatattt atcttggtgg ttatggaaga agaagtggac ttggacctga
     6481 gttctttgct aaaggcttac tacaagcacc agaccaacca agtgatgcaa cgattactat
     6541 caattctata ttgaaacatt caaaatctga tagtaaagaa ggagaacgat tacaagtact
     6601 tgatccaact acgagattta aagacgcaac agatcttcaa aaatacgtcc acaatatgtt
     6661 tgatgttgtt tatatgttgg aatatctcga aggtaa
//
LOCUS       DAVAGB010000074         6681 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVAGB010000074 DAVAGB010000000
VERSION     DAVAGB010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6681
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.075"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(28..297)
                     /locus_tag="VQO19_001988"
                     /pseudo
     CDS             complement(28..297)
                     /locus_tag="VQO19_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            489..2255
                     /gene="patB"
                     /locus_tag="VQO19_001989"
     CDS             489..2255
                     /gene="patB"
                     /locus_tag="VQO19_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HET1350199.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTHVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMGLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            2394..3083
                     /locus_tag="VQO19_001990"
     CDS             2394..3083
                     /locus_tag="VQO19_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET1350200.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            3087..3266
                     /locus_tag="VQO19_001991"
     CDS             3087..3266
                     /locus_tag="VQO19_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350201.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            3253..4602
                     /locus_tag="VQO19_001992"
     CDS             3253..4602
                     /locus_tag="VQO19_001992"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HET1350202.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWETFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            4726..6186
                     /locus_tag="VQO19_001993"
     CDS             4726..6186
                     /locus_tag="VQO19_001993"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HET1350203.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            6200..6634
                     /locus_tag="VQO19_001994"
     CDS             6200..6634
                     /locus_tag="VQO19_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET1350204.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     EFNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         2090 a         1296 c         1437 g         1858 t
ORIGIN      
        1 gcatgctttg gcagcttgta tgagtaccta ccgcagatga ggggaacccc gtttgaccat
       61 tcttcctgct aaatcaatct gacctgactg ataaatagaa gaatccagtc cagcgaaagc
      121 ttgtaattga gcaggattat caaaggcatg aatatttcga atctcggcta aaatgaccgc
      181 ccctaaacga ttctcaatcc cagtaaccgt cgtgatgacc gagttgaact cagccatcaa
      241 gtcattgaca cattttttcg ccttgtcaat gagcctcttg taatgtttga tgatttcatt
      301 acacgagata aaacgtctat gcgttatcaa actcattacc aattaaaaca aaaagctgtg
      361 gttagatcct ttcggaaatc gtcaagcgat tggaggaaat gaactaatcc acagcggctt
      421 attccaagta taccacttgg gctttggcag tagctaactg cgctaaatat aatataagga
      481 ggagtaaaat gaagacagtt caattttttt ggcattattt taaggtctac aagttctcat
      541 ttgtagttgt catcctgatg attgttctgg cgacttttgc ccaagccctc tttccagtct
      601 tttctggaca agcggtgacg cagctagcca atttagttca agcttatcaa aatggcaatc
      661 cagaacttgt atggcaaagc ctatcaggaa tcatggtcaa tcttggcctg ctggttttgg
      721 ttctatttat ctctagtgta atatacatgt gtctcatgac gcacgtgatt gcagaatcga
      781 ccaacgagat gcgcaaaggc ctctttggta agcttgctca gttgacggtt tctttctttg
      841 accgtcgaca agatggcgat atcctgtctc attttaccag tgatttggat aatatcctcc
      901 aagcctttaa cgaaagcttg attcaggtca tgagcaatat tgttttatac attggtctga
      961 ttcttgtcat gttttcgaga aatgtgacgc tggctctcat caccattgcc agcaccccat
     1021 tggctttcct tatgctgatt ttcatcgtga aaatggcacg caaatacacc aacctccagc
     1081 agaaagaggt agggaagctc aacgcctata tggatgagag catctcaggc caaaaagccg
     1141 tgattgtgca aggaattcaa gaggatatga tggcaggatt tcttgaacaa aatgagcgcg
     1201 tgcgcaaggc aacctttaaa ggaagaatgt tctcaggaat tcttttccct gtcatgaatg
     1261 ggatgggcct gattaataca gccatcgtca tctttgctgg ttcggctgta cttttgaatg
     1321 ataagtctat tgaaacaagt acagccctag gtttgattgt tatgtttgca caattttcac
     1381 agcagtacta ccagcctatt atccaagttg cagcgagttg gggaagcctt cagttggcct
     1441 ttactggagc tgaacgaatt caggaaatgt ttgatgcaga ggaggaaatc cgacctgaaa
     1501 aggctccaac cttcactaag ttgcaagaaa gtgttgaaat cagtcatatc gatttttcat
     1561 acttgcctga taaacctatt ttgaaagatg tcagcatttc tgcccctaaa ggccagatga
     1621 cagcagttgt tgggccgaca ggttcaggaa aaacgactat tatgaacctc atcaatcgct
     1681 tttatgatgt tgatgctggt ggtatttatt ttgatggtaa agacattcgt ggctatgact
     1741 tagatagtct tagaagcaag gtgggaattg tattgcaaga ttcggtcttg tttagcggaa
     1801 cgattcgaga caatatccga tttggtgtgc cagatgctag tcaggaaatg gttgaggtag
     1861 cagcaaaagc aacccacatt cacgactata tcgaaagttt gcctgataag tacgatactc
     1921 ttattgatga tgaccagagc atcttttcaa cagggcagaa gcaattgatt tcaatcgctc
     1981 gaaccctgat gacagatcca gaagttctca ttctcgatga agcaacttca aacgtagata
     2041 cggtgacaga aagcaagatt cagcatgcca tggaggtggt tgtagcaggt agaactagtt
     2101 tcgtcattgc ccaccgcttg aaaaccattc tcaatgcaga tcagattatt gtccttaaag
     2161 atggagaagt cattgaacgt ggtaaccacc atgaactttt gaagctaggt ggcttttatt
     2221 cagaactcta tcacaatcaa tttgttttcg aataagaaag aagttgtcct atgtgggcag
     2281 ctttttcttg tccataaaaa atgtttatca cagccttaaa aaaaacatat tagacgaaag
     2341 tcattttgag tgatatgata ggactatcgt tagcattcga aaggagaggc atcatggcta
     2401 gaacggttgt aggagttgct gcaaatctat gtcccgtaga cgcagaaggc aaaatcattc
     2461 attcatctgt atcttgtaga ttcgcagaga tcattcgtca agtcggtggt ctccctttag
     2521 tcattcctgt tggtgatgag tcagttgtac gtgattatgt ggaaatgatt gacaaactca
     2581 ttttgacagg aggccaaaat gttcatcctc agttttatgg agagaaaaag accgtcgaaa
     2641 gcgatgatta caatctggtc cgtgacgaat ttgaattggc actcttgaag gaagcgcttc
     2701 gtcagaataa accaattatg gcaatctgtc gcggtgtcca acttgtcaat gttgcctttg
     2761 gtggaaccct caatcaagaa atcgaaggtc actggcaagg actacctttc gggacatctc
     2821 actctattga gacagtagaa ggaagcgtgg tggctaagct atttgggaaa gaaagtcagg
     2881 tcaactcagt ccatcgtcaa agcattaaag atttggcacc taatttccgt gtaactgcca
     2941 ttgattcaag agaccaaact attgaagcga ttgagtctat cgacgagcac cgcattatcg
     3001 gtttacagtg gcatccagag tttctggtta atgaagaaga tggcaattta gaattatttg
     3061 agtatttatt gaatgaactg taacgattgg aacatctggt cgttctttct tttatttttt
     3121 caaaattttt agaatgtggc attttacgca aacgtttgaa ttctgataaa aattggagaa
     3181 attcgacaaa aaaacttgaa aaaaacgaag gtaagcgtta tgatagaaaa gaagaaatat
     3241 tggaggaaga acatgtcaca tattaaattt gattattcaa aagttttaga caaatttgtt
     3301 gcaccacatg aagtggaata catgcaatca caagtaacag cagcagatga attgatccgt
     3361 aaaggaactg gtgctggtag cgacttcttg ggatggttgg accttcctga aaaatacgac
     3421 cgcgaagaat ttgaccgcat cttgaaagct gctgagcaaa tcaagtcaga cagcgatgtt
     3481 ttggttgtga tcggtattgg tggatcttac cttggtgcaa aagcagcaat cgacttcttg
     3541 aatcaccatt ttgctaactt gcaaacaaaa gaagaacgca aagctccaca aatcctttac
     3601 gcaggaaact caatctcatc tacttacctt gctgacttgg tagagtatgt tgcagacaaa
     3661 gacttctcag taaacgtaat ttctaaatca ggtacaacaa ctgaaccagc gattgctttc
     3721 cgtgtcttta aagaactctt ggttaagaaa tacggtcaag aagaagctaa caaacgtatc
     3781 tatgcaacaa ctgaccgcca aaagggtgct gttaaggttg aagcagacgc taacggttgg
     3841 gaaacatttg ttgttccaga tgatatcggt ggacgcttct cagtattgac agccgttggt
     3901 ttgcttccaa tcgcagcatc aggagctgac atcaaagctc ttatggaagg tgcgaatgca
     3961 gctcgcaaag actacacttc agacaaaatc tctgaaaacg aagcttacca atacgcagcc
     4021 gttcgtaaca tcctttatcg taaaggctat gcaactgaga tcttggtaaa ctatgagcca
     4081 tcacttcaat acttctcaga atggtggaaa caattggctg gtgaatcaga aggaaaagac
     4141 caaaaaggta tctacccaac ttcagccaac ttctcaactg acttgcactc acttggtcaa
     4201 tttatccaag aaggaactcg tatcatgttt gaaacagttg tccgtgttga caaacctcgt
     4261 aaaaacgtgc ttattcctac tttggaagaa gaccttgacg gacttggtta ccttcaagga
     4321 aaagacgttg actttgtaaa caaaaaagca actgacggtg ttcttcttgc ccacacagat
     4381 ggtgatgtac caaacatgta tgtgactctt ccagagcaag acgctttcac tcttggttac
     4441 actatatact tcttcgaatt ggcaattgcc ctttcaggtt acttgaatgc tatcaaccca
     4501 tttgaccaac caggtgttga agcttataaa cgtaacatgt ttgcccttct tggaaaacca
     4561 ggatttgaag aattgagcaa agaacttaac gcacgtctat aatagaagaa aagagtggtt
     4621 tgcccactct ttttactctc tttatccata gaaattggac tcagccaaga cttgtgatat
     4681 aatatagaaa gcaaaaaggc agacgcctag ataataggag aaactatgtc aaaagatatc
     4741 cgcgtacgtt acgcaccaag tccaacagga ctactacaca tcggaaatgc tcgtacagca
     4801 ttgtttaatt acttgtatgc gcgccatcat ggtggaacat ttctcatccg tatcgaagat
     4861 actgaccgta aacgccatgt cgaggatggt gaacgttcac aacttgaaaa ccttcgctgg
     4921 ttaggcatgg attgggatga aagtccagaa tcacatgaga attatcgcca gtctgagcgt
     4981 ttagacttgt atcaaaaata cattgaccaa ctattagctg aaggaaaagc ctataaatct
     5041 tacgttacag aagaagagtt ggcagctgaa cgcgaacgcc aagaagtagc tggcgaaaca
     5101 ccacgctaca tcaatgaata ccttggtatg agtgaagaag aaaaagcagc ttacatcgca
     5161 gaacgtgaag cagcagggat catcccaact gttcgtttgg ctgtcaatga gtcaggtatc
     5221 tacaagtggc atgatatggt caaaggcgat atcgaatttg aaggtggcaa tatcggtggt
     5281 gactgggtta tccaaaagaa agacggttac ccaacttaca actttgccgt tgttatcgat
     5341 gaccacgata tgcaaatctc tcatgttatc cgtggagatg accatattgc taatacacca
     5401 aaacagctta tggtctatga agctcttggt tgggaagctc cagagttcgg tcacatgacc
     5461 ttgattatca actctgagac tggtaagaag ttatctaaac gtgatactaa tacacttcaa
     5521 tttatcgaag attaccgaaa gaaaggttac cttccagaag cagtctttaa ctttattgct
     5581 cttcttggtt ggaacccagg tggtgaagat gagattttct ctcgtgaaga actcattaaa
     5641 ctttttgatg aaaaccgcct cagcaagtca ccagcagcct ttgatcagaa aaaactagac
     5701 tggatgagca atgattatat caagaatgca gaccttgaaa ccatctttga aatggcaaaa
     5761 ccattcttag aggaagcagg ccgtttgact gacaaggctg aaaaattagt tgagctctat
     5821 aaaccacaaa tgaaatcagt agatgagatt atcccattga cagatctttt cttctcagat
     5881 ttcccagaat tgacagaagc agagcgcgaa gtcatgacgg gtgaaacagt tccaacagtt
     5941 cttgaagcat tcaaagcaaa acttgaagcg atgacagatg atgaatttgt gacagaaaat
     6001 atcttcccac aaattaaagc agtccaaaaa gaaacaggta ttaaagggaa aaatcttttc
     6061 atgcctattc gtatcgcagt ttcaggcgaa atgcatgggc cagaattacc agatacaatt
     6121 ttcttgcttg gacgtgaaaa atcaattcag catatcgaaa acatgctaaa agaaatctct
     6181 aaataaagag gatacaataa tggacatctg ggaaaagatg tacgaagaag cacagaaact
     6241 atacaatcca catgaagtat cagactttgt ttatgccaat catgttgtag ctgcagtaga
     6301 agcaggagat ggacaaatat ttacaggatt ctgtatggag ggaacctgtg gtgttttcca
     6361 tctctgcgca gaacgggcgg ccctcttcaa tatgtaccaa ttttcaggac aaactaaggt
     6421 taagaaagta ttagcctttc gagacaaacc accttatggt ggaagttcag ccatgccttg
     6481 cggtgcttgt agagaattcc ttttagagtt taatgctgaa aataaagatg cagaattcat
     6541 gatggactat aatataagaa aaacagttaa agtcgcagaa ctaatccctt attggtgggg
     6601 agaagaacgt gcttctaagt ttaatgagcg atagaagagt cagtataatt ctggcttttt
     6661 ttactataag ttgaaaaaat a
//
LOCUS       DAVAGB010000075         6642 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVAGB010000075 DAVAGB010000000
VERSION     DAVAGB010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6642
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.076"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(123..419)
                     /locus_tag="VQO19_001995"
                     /pseudo
     CDS             complement(123..419)
                     /locus_tag="VQO19_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(409..570)
                     /locus_tag="VQO19_001996"
     CDS             complement(409..570)
                     /locus_tag="VQO19_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002875407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HET1350205.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTVQNLDGAYSLYKMA
                     NPEGVEYGN"
     gene            640..1404
                     /locus_tag="VQO19_001997"
     CDS             640..1404
                     /locus_tag="VQO19_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HET1350206.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            2014..3393
                     /locus_tag="VQO19_001998"
     CDS             2014..3393
                     /locus_tag="VQO19_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET1350207.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            3407..4072
                     /locus_tag="VQO19_001999"
     CDS             3407..4072
                     /locus_tag="VQO19_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HET1350208.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            4207..4365
                     /locus_tag="VQO19_002000"
     CDS             4207..4365
                     /locus_tag="VQO19_002000"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350209.1"
                     /translation="MKIKDQTRKLATGCSKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NIYTARRR"
     gene            4427..4876
                     /locus_tag="VQO19_002001"
     CDS             4427..4876
                     /locus_tag="VQO19_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET1350210.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVEILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKGHGGVVNCGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDAFVTNFVYEKEGQSRKKSMSYESVLPVRQIFD"
     gene            5033..5443
                     /locus_tag="VQO19_002002"
     CDS             5033..5443
                     /locus_tag="VQO19_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HET1350211.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKRIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            5559..>6642
                     /gene="pavB"
                     /locus_tag="VQO19_002003"
     CDS             5559..>6642
                     /gene="pavB"
                     /locus_tag="VQO19_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HET1350212.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRSNGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVKDNVKDSIDVPAAYLEQAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKASDKAPW"
BASE COUNT         1807 a         1273 c         1530 g         2032 t
ORIGIN      
        1 atccacaacc ttaaaacagt gttttgagca gcctgcggct aacttcctag tttgcacttt
       61 aattttcatt gagtattact tcatcttctc atgaaattga gtttttgccc agctcctctt
      121 gattattcta cttgaccggg ccaagtattc ataccacctt ctacgttggt aacggtgagg
      181 ccttgggagc tgagaaattg gcaggtagat gcagagcgga ctcctccttg acaaataaca
      241 tagtattcat ggtcaggttt gagttctttg tagccttgct ctaaggtact taatggaaga
      301 tttttggcac ctggtgcatg tcctgcttgg aattcatgtg cttcacggac atcgataagt
      361 tctagatttt cattttagta ttttccataa aagtcagcca tgctgatact agtttccata
      421 ttctactcct tctgggttag ccattttgta tagtgaataa gcgccgtcaa ggttttggac
      481 ggtaaatcct gcttgcttga ggataggctc tgcgatatag ctgcgcaaac cactgtggca
      541 gctgacgatg taggcttgtt ttttgtccag ttcatcagct tcctccttga cactttgtca
      601 gtttttgata caatagtaca aaattagagg aggtgggcta tgattcagaa acatgcgatt
      661 cccattttag agtttgatga taatcctcag gcggttatca tgcccaatca cgaggggttg
      721 gatttgcagt tgccaaagaa gtgtgtctat gcttttttag gtgaggagat tgaccgctat
      781 gcgagggaag taggggcgaa ctgtgttggc gaattcgttt ctgctaccaa gacctatcca
      841 gtctatgtca tcaactacaa gggtgaggag gtctgtctgg ctcaggctcc tgttggctcc
      901 gctccagcag cccagtttat ggattggttg attggctatg gtgtggagca gattatctct
      961 actgggacct gtggtgtcct agctgatata gaggaaaatg cctttctagt ccctgttcgc
     1021 gctttgcgag atgagggagc cagttaccac tatgtggcac cttgtcgtta tatggaaatg
     1081 cagccagagg ctattgctgc tattgaggaa gttttggaag acagagggat tccttatgaa
     1141 gaagtcatga cctggacgac agacggtttt taccgagaaa cggctgaaaa ggtggcttat
     1201 cgtaaggaag aaggctgtgc tgttgtggag atggagtgtt ctgctcttgc ggcagtagct
     1261 caattgcgtg gggttctctg gggtgaattg ttgttcacag cagattctct agcggacttg
     1321 gaccagtacg acagtcgtga ctggggctcg gaagctttta ataaggcgct agaactgagt
     1381 ttagcaagtg ttcaccacct ttagttgtac aggcaaagga tttgttttat cataaaatgt
     1441 ctagctcata cttttcaaaa atatgtttaa acgaggtcac cttcctcttg tcctaggcat
     1501 gttgaggttg ggaaaaatct ttaaaatcag aaaaacgtat catatcaggt gatgaaaatt
     1561 ttgatactat gcgttttatg ttggtaagat ttagagtgag atgaaatgat actcttcgaa
     1621 aatctcttca aaccaggtca gcttcacctt gccgtataga tgttactgac ttcgtcagtt
     1681 ctatctgcaa cctcaaaaca gtgttttgag ctgacttcgt cagttctatc cacaacctca
     1741 aaacagtgtt ttgagcaacc tgtgactagc tttctaagcg atgccttggt tctcattgcc
     1801 tataatcaaa aagagaaatt ttctcctgaa aagcatatag agtagctggc gttaaaagct
     1861 cctgtcttgc ttttttgacc tatagtcaca tctatcaagt attgttcttg cctaagctat
     1921 caataaaaag gtggcatttt ttaggcttgg tgttagtgaa ttttgcctta tcctatctaa
     1981 gtcatttcga gctttttatg gtacaatgga aacatgttat tcaaattatc taaggaaaaa
     2041 atagagctag gcttatctcg tttatcgcca gcccgtcgta tttttttgag ttttgccttg
     2101 gtcattttac taggctctct tcttttgagc ttgccctttg tccaagttga aagctcacga
     2161 gcgacttatt ttgatcatct tttcactgct gtctctgcag tctgtgtgac aggtctctca
     2221 acccttccag tagctcacac ctataatatc tggggccaaa taatctgttt gctcttgatt
     2281 cagatcggtg gtctagggct catgactttt attggggttt tctatatcca gagcaagcaa
     2341 aagcttagtc ttcgtagccg tgcaactatt caggatagtt ttagttatgg agaaactcga
     2401 tctttgagaa agtttgtcta ttctattttt ctcacgacct ttttggttga gagcttggga
     2461 gctattttgc ttagttttcg ccttattcct caacttggct ggggacgtgg tctttttagt
     2521 tccatttttc tagcgatctc agccttctgt aatgccggtt ttgataattt agggagcacc
     2581 agtttatttg cttttcagac cgatttactg gtcaatctgg tgattgcagg cttgattatt
     2641 acaggcggcc ttggttttat ggtctggttt gatttggctg gtcatgtagg aagaaagaaa
     2701 aaaggacgtc tgcactttca tacgaagctt gtactattat tgactatagg tttgttgtta
     2761 tttggaacag caactactct ctttcttgag tggaacaatg ctggaacgat tggcaatctc
     2821 cctgttgccg ataaggtttt agttagcttt tttcaaacag tgacgatgcg aacagctggc
     2881 ttttctacga tagattatac tcaggctcat cctgtgactc ttttgattta tatcttacag
     2941 atgtttctag gtggggcacc tggaggaaca gctgggggac tcaagattac gacatttttt
     3001 gtcctcttgg tctttgcacg aagtgagctt ctaggcttgc ctcatgccaa tgttgcgaga
     3061 cgaacgatcg cgccgcgaac ggttcaaaaa tcctttagtg tctttattat ctttttgatg
     3121 agcttcttga taggattgat tctgctaggg ataacagcca aaggcaatcc tccctttatc
     3181 cacctcgtat ttgaaaccat ttcagctctt agtacagttg gtgtaacggc aaatctgact
     3241 cctgaccttg ggaaattggc tctcagtgtt atcatgccac ttatgtttat gggacgaatt
     3301 ggtcccttga ccttgtttgt tagcttggca gattaccatc cagaaaagaa agatatgatt
     3361 cactatatga aagcagatat tagtattggt taagaaagga aagagcatgt cagatcgtac
     3421 gattggaatt ttgggcttgg gaatttttgg gagcagtgtc ctagctgccc tagccaagca
     3481 ggatatgaat attatcgcta ttgatgacca cgcagagcgc atcaatcagt ttgagccagt
     3541 tttggcgcgt ggagtgattg gtgacatcac agatgaagaa ttattgagat cagcagggat
     3601 tgatacctgc gataccgttg tagtcgcgac aggtgaaaat ctggagtcga gtgtgcttgc
     3661 ggttatgcac tgtaagagtt tgggggtacc gactgttatt gctaaggtca aaagtcagac
     3721 cgctaagaaa gtgctagaaa agattggagc tgactcggtt atctcgccag agtatgaaat
     3781 ggggcagtct ctagcacaga ccattctttt ccataatagt gttgatgtct ttcagttgga
     3841 taaaaatgtg tctatcgtgg agatgaaaat tcctcagtct tgggcaggtc aaagtctgag
     3901 taaattagac ctccgtggca aatacaatct gaatattttg ggtttccgag agcaggaaaa
     3961 ttccccattg gatgttgaat ttggaccaga tgacctcttg aaagcagata cctatatttt
     4021 ggcagtcatc aacaaccagt atttggatac cctagtagca ttgaattcgt aaagagggat
     4081 gacccctctt ttttgatgcc taagatggca aatagagaca gaagcccctt gtcttctagt
     4141 aaaagttctt caaaggctgg actttatggt aaaatagaaa gaagtgacaa gagagagtaa
     4201 tactcaatga aaatcaaaga tcaaactagg aaactagcta cgggctgctc aaaacactgt
     4261 tttgaggttg tggatagaac tgacgaagtc agctcaaaac actgttttga ggttgcagat
     4321 agaactgacg aagtcagtaa catctatacg gcaaggcgac gttgacgcgg tttgaagaga
     4381 ttttcgaaga gtataagaaa aaatcagtcc cctaaaggag cagattatga agttattgtc
     4441 tatcgccatt tctagctata atgcagcagc ctatcttcat tactgtgtgg agtcgctagt
     4501 gattggtggt gagcaagttg agattttgat tatcaatgac gggtctcagg atcagactca
     4561 ggaaatcgct gagtgtttag ctagcaagta tcctaacatc gttagagcca tctatcagga
     4621 aaataaaggc catggcggtg tggtcaattg cggtttggca gaggcttctg ggcgctattt
     4681 taaagtagtt gacagtgatg actgggtgga tcctcgtgcc tacttgaaaa ttcttgaaac
     4741 cttgcaggaa cttgagagca agggtcaaga ggtggatgcc tttgtgacca attttgtcta
     4801 tgaaaaggaa ggtcagtctc gtaagaagag tatgagttac gagtcagtct tgcctgttcg
     4861 gcagattttt gactaggacc aggtcggaaa tttctccaaa ggccagtata tcatgataca
     4921 ctcgctgatt tatcggacag atttgttgcg tgctagccag ttctaactgc ctgaacatac
     4981 tttttatgtc gatgatctct ttgtctttac gccccttcag caggtcaaga ccatgtacta
     5041 tctgcctgtc gatttctatc gttatttgat tgggcgtgag gaccagtctg tcaatgagca
     5101 agtgatgatt aagcgcattg accagcaact caaggtcaat cgactcttgg tagaccagct
     5161 tgatttgtcc caagtgagtc atcctaaaat gcgagaatat ctgctgaatc atattgaaat
     5221 cacgacggtg atttccagta ccctgctcaa ccgatctgaa acagcggagc atctggcaaa
     5281 aaaacgccaa ttgtggacct atattcagca gaaaaatcca gaagtctttc aggctattcg
     5341 taagaccatg ttgagccgtt tgaccaaaca ttctgtcttg ccagatcgca aactgtccaa
     5401 tgtcgtctat caaatcacca aatctgttta tggatttaat taatataagt gttttataag
     5461 agggatttaa gaaaaatttt aactttttct tagtcctttt taatttcagg agattatact
     5521 agagtcatca aataaagaaa gactctaagg agaatcctat gaaattcaat ccaaatcaaa
     5581 gatatactcg ttggtctatt cgccgtctca gtgtcggtgt tgcctcagtt gttgtggcta
     5641 gtggcttctt tgtcctagtt ggtcagccaa gttctgtacg tgccgatgtg gtcaatccga
     5701 ccccaggtca agtcttacct gaagagacat cgggaacgaa agagggtgac ttatcagaaa
     5761 aaccaggaga caccgttctc actcaagcga aacctgaggg cgttactgga aatacgaatt
     5821 cacttccgac acctacagaa agaactgaag tgagcgagga aacaaactct tctagtctgg
     5881 atacactttt tgaaaaagat gaagaagctc aaaaaaatcc agagctaaca gatgtcttaa
     5941 aagaaactgt agatacagct gatgtggatg ggacacaagc aagtccagca gaaactactc
     6001 ctgaacaagt aaaaggtgga gtgaaagaaa atacaaaaga cagcatcgat gttcctgctg
     6061 cttatcttga aaaagctgaa gggaaaggtc ctttcactgc cggtgtaaac caagtaattc
     6121 cttatgaact attcgctggt gatggtatgt taactcgtct attactaaaa gcttcggata
     6181 atgctccttg gtctgacaat ggtactgcta aaaatcctgc tttacctcct cttgaaggat
     6241 taacaaaagg gaaatacttc tatgaagtag acttaaatgg caatactgtt ggtaaacaag
     6301 gtcaagcttt aattgatcaa cttcgctcta atggtactca aacttataaa gctactgtta
     6361 aagtttacgg aaataaagac ggtaaagctg acttgactaa tctagttgct actaaaaatg
     6421 tagacatcaa catcaatgga ttagttgcta aagaaactgt cgaaaaagct gttaaagata
     6481 acgttaaaga cagtatcgat gttccagcag cctacctaga acaagccaag ggtgaaggtc
     6541 cattcacagc aggtgtcaac catgtgattc catacgaact cttcgcaggt gatggcatgt
     6601 tgactcgtct cttgctcaag gcatctgaca aggcaccatg gt
//
LOCUS       DAVAGB010000076         6475 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVAGB010000076 DAVAGB010000000
VERSION     DAVAGB010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6475
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.078"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(104..3205)
                     /locus_tag="VQO19_002004"
     CDS             complement(104..3205)
                     /locus_tag="VQO19_002004"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HET1350213.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVLEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQIMLNSANSDYVTDALEAGFEVAPLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            3553..5826
                     /locus_tag="VQO19_002005"
     CDS             3553..5826
                     /locus_tag="VQO19_002005"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HET1350214.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELKVKLPHKIELEKPQLNLVQPQGQAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCKTFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQAFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRSDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            5843..6313
                     /locus_tag="VQO19_002006"
     CDS             5843..6313
                     /locus_tag="VQO19_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET1350215.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
BASE COUNT         1961 a         1430 c         1105 g         1979 t
ORIGIN      
        1 caaaacagca atacgtttca tattggttta tgctcctttt tcttttaaca ttcttcttga
       61 ttatatcaca tttgatttta aaattcttct attttccgta tttttagcga taaatcgttt
      121 tcataacgat ttcattcaat ttctcctcta attcattgga tttagctaca aaatgatggg
      181 gagaaacgat ggttttctgt tcctcttcat accggatgat gactgggatt gggcctttaa
      241 attgttctaa aatacgtgaa atttcttgat ccgattcatg atttttcacc tgtatccaaa
      301 agcgttcagc aactgcttct cttatttctt gtgcaatcat ttgcagacgg ccatcacgtg
      361 attgtatttt tccttttaca tagtagaagg ctccctcttt tatttcctgt ccgacctgac
      421 gatataagtc tgaaaagaga gtgacatcca attttttctt actatcatct gcctgtaaga
      481 aggccatatt ttcacccttt ttggtacgaa tcacttttat tttctgaact tcaaccaaaa
      541 taatagcata gctattttct gacaaatttc cgattggggt aatcgggtaa atagccttac
      601 ttgcaatagc ttgtagtgga tgtttgctga cacctatccc taaaagctct tgttccatat
      661 aaaatttttc ttgttccgtc caatcttccg attcctgcca actataaata gcatctccaa
      721 acaaacttcc caactctttc acaaattcaa atagattagc taagttatta aatacttttt
      781 gacgattttt ttcaaatgaa tcgaaaagac caacttttac caaaggttct agcagaggaa
      841 gtttcagata attctcaggt aatttagcta taaaatcttc aatgttagaa taaggtctat
      901 gttcaataat ccagagagct aaatcattac tgactccttt aatggatttc aaacctagat
      961 agatggcctt gttggcaatt ttatcgtgat agggaatcgt gttgatggac aatggggcta
     1021 cttcaaaacc tgcttctaag gcatctgtta cataatcact gttagcagaa ttcaacataa
     1081 tctgataaaa tatggctgga taatgtgttt taaaataagc caactggaag gccaaggctg
     1141 agtaggcgta ggcgtgtgac ctgttaaaac catagcctgc aaacttctcc agaacatcaa
     1201 aaacctgctc tgctttttcc gcagtatggc ctgcttctat ggagccttga ataaaggaag
     1261 ccctcatctc atgcatagca gaagcatcct ttttacccat agctcgacgc aaaatatcgg
     1321 ccttcccaag actaaatcca gcaaatcgct gggcaacctg cataacctgc tcctgataga
     1381 gcattatgcc gtaggttgga gccaaaatat cctccagtac tggatccaga acagtcactt
     1441 cttcctgccc atgctttctt gccacaaaat tattgatata gtcactagca cccggtcgat
     1501 ttagagaagt agtcgcgacg acatcttcaa aacagactgg ttgcacacgc ttaagcagac
     1561 gaatggcacc tggttgctca aattgaaaga taccttttgt attaccagag gcaaataaag
     1621 ctaacgtttc tttgtcttct aaatcgattt cttcaatttt cagatgaata ccttctgttt
     1681 cagcaagcaa ctcttgcatc ttctggacaa aggtcaaatt tcgtagtccc agaaagtcca
     1741 tcttcaaaag tccgctagcc tcaactccat gagcatcata ctgagtcagt ggaatttcat
     1801 caccatactt tagaggaatg tagttggtta aatcttggtc actaattaca acaccagccg
     1861 catggacaga ggtttgcctt ggatagccct ctatcttgca agcaatctca aaagcttttt
     1921 ggtattctaa cttactattg atttgctgac gaaactggag attgccctca taggccgact
     1981 taagattgtc acgaaaactg attttcttag taattgcaga taattcatac tctggcacac
     2041 caaagcgttt caagacatct cgaagagctt gcttggctcc aaaggttgaa aaagtaacga
     2101 tttgtgccgc atgtttacta ccatatttat taccaacata tctgataaaa tctggacgat
     2161 aaatatctgg gatatcaata tcaatatcag gcatggtata gcgttcacga ttaagaaagc
     2221 gttcaaaaat cagatttttc tctactgggt caatccccgt gatgtctaag gcataagaaa
     2281 ccaaactgcc tactgcagaa ccccttccca ttcccatata atagccattc gatcgtccaa
     2341 aacgcaacaa atcccaaaca accaagaaat aatcatcaaa gcccatatca tgaataacag
     2401 acaattcttg gtctagtcta tcttgatatt ctttactagt caaccccttc tgaacaagcc
     2461 ccagttcagc acgctctctc aactcctcta ctgctggtct agctggatta aaacgaggca
     2521 gtttcagact agtatccaag tcgtaagaaa tgcctgaaat aagcttttct aaattgtcca
     2581 aagcttgcgg aaaacgctct tggaatagtt tctctaaaga acttgctgat ataaagacat
     2641 cttgtctcga acgcaaggga acttctctga gcggtagatt ttctttaatc gctgttaaaa
     2701 cttgaagaac ttctctatcc ctgctttcaa aagcgttgac ccgataaaga ggtaagatag
     2761 gatgatgaaa ttcgcttgct agtgtttctg gataaacccc tatatagtaa tcacagccta
     2821 gttctaacga ctcaactcta tcaaaataag gcacaatgac cgcgatatcc tccaggtact
     2881 gggacaggac tgaccaagtt ttctccccct gcatcttggc tgtcgaaagc ttcatcaact
     2941 gctgatagcc cacactagat agagctaaaa agcgcaaatt cacttcctga tcatctacaa
     3001 acactgtcat ttcaagccct agcaaaggat gaatgccgta tttttttgta atctctagaa
     3061 agtcgaaagc gccataaaga ttgtcaatat ccatcatagc caaatgagtg tagccgtatt
     3121 ctttagctgc tctcacatac ttttcgatcg aaatgacgct ttccataaaa ctatagactg
     3181 tttttgtatc tagttgtgcg atcaatttac acttctcctc tatccttctc actatattat
     3241 accattttca cctataaatg gcttctcttg agaaaaattt catcagctta ctaatttatt
     3301 ttctattcat ttgtattttt gtcatcattt ttatatttat actatattgt atataaaaat
     3361 agaaagcata taatataaat ctcctagaac ttttataccc tatctatttt attcttattg
     3421 ttactctgtt ctctatattg aatttagtac tttattcatt tttattggat tatttccttt
     3481 tgaagttaac aattcccttt ctgctttttt tttgatataa taaccttaac tgtcattcta
     3541 tatggaggtt ctatgcgttt taatcaatat agttatatca attttccaaa agaaaatgtc
     3601 ttatctgaac taaaaaaatg tggctttgat ttacaaaata cagccaatca caaagactca
     3661 cttgaaacct ttttacgtcg tttctttttc acttatcaag acaccaacta cccactttct
     3721 atcctagcag ctgataaaaa aacagacctg ctgacatttt ttcaatcaga agatgaactg
     3781 acagcagata ttttttatac tgttgctttt caacttttag gcttttctta tttggttgac
     3841 ttcgaagata gtgacgtttt tcgtaaagaa actggatttc ccattatata tggtgacttg
     3901 attgaaaatc tctatcagtt actcaatact cgcaccaaaa aaggaaatac tcttatcgac
     3961 caacttgtta gtgatggtct tattccggag gataatgact accactactt taacggcaag
     4021 agtttggcta ctttttctaa ccaggatgtc attcgtgaag tcgtttacgt tgagtctcgt
     4081 gtcgatactg accaaaaagg gctatcagac ctagtaaagg ttagcattat tcgccctcgt
     4141 tttgatggaa aaatccctgc catcatgaca gccagccctt atcatcaggg aaccaatgac
     4201 aaggctagtg acaaggctct ctacaagatg gagggcgagc ttaaggttaa gcttcctcac
     4261 aagattgagc tagagaaacc tcaactaaat ctcgtccaac cccaaggtca agctgagctt
     4321 atagcagagg ctgaggaaaa gctaactcac atcaactcta gctatacact aaacgactac
     4381 ttccttccga gaggctttgc caatctctat gtctcaggtg ttggtaccaa agactcgaca
     4441 ggtttcatga ctaatggaga ctaccagcaa atcgaggctt ataaaaatgt catcgattgg
     4501 cttaacggcc gttgccgtgc ctttactgat cacacgcgcc agcgtcaagt caaggctgat
     4561 tggtcaaacg gaaaagttgc tacaacggga ctttcctatc taggtaccat gtccaatggt
     4621 cttgcgacta caggagtcga tggtttagaa gttatcattg ccgaggcagg aatttcatca
     4681 tggtacaact actaccgtga aaacggtctg gtgactagcc caggtggtta tccaggtgag
     4741 gactttgact cccttgctga gttaacctat tctcgtaatc tcttagctgg cgactatatc
     4801 cgtggcaatg aagctcacca agctgactta gaaaaagtga aagctcagct agaccgaaaa
     4861 actggggact acaatcagtt ttggcatgac cgcaattatc tgctcaatgc ccataaagta
     4921 aaggcagagg ttgtctttac tcatggttct caggattgga atgtcaaacc acttcatgtt
     4981 taccagatgt tccatgctct tcctactcat atacacaagc atctcttttt ccataatggt
     5041 gcccatgttt acatgaacaa ttggcaatca attgacttcc gtgagtccat aaatgcctta
     5101 ttaaccaaga aattactagg acaggaaaca gactttcaac ttcctactgt tatctggcag
     5161 gacaatacag ctccacagac ttggttatca cttgataact tcggtgggca agaaaactgt
     5221 aaaaccttct cacttggtca agaagagcaa gctattcaaa accagtaccc agataaggat
     5281 tttgagcgct atggtaagac ataccaagcc ttcaatacag agctctatca agggaaagcc
     5341 aatcagatta ctattaacct tcctgtgact aaagatctcc acctaaacgg tcgcgctcag
     5401 ctcaatcttc gtatcaaatc cagtacaaac aaggggctct tatctgccca actgctagaa
     5461 tttgggcaaa agaaatacct acaaccttat ccagctattt taagtgctag aaccattgac
     5521 aacggtcgct atcacatgtt ggaaaatctc tgtgaattgc catttagacc agaggcacaa
     5581 cgagtcgtga caaaaggtta ccttaattta caaaatagaa gtgatttact gttagtagag
     5641 gatattactg cagatgaatg gatggacgtt caatttgaac tgcagccaac tatttacaag
     5701 ctaaaagaag gagacactct ccgtttagtc ctctatacta ctgactttga aatcaccatc
     5761 cgtgacaata cagactacca cttgactgtc gacctcgctc agtccatgct taccttacct
     5821 tgctaaaagg agttacatta ttatgaataa atcagaacac cgccaccaac ttatacgcgc
     5881 tcttatcaca aaaaacaaga ttcatacaca ggctgagttg caagcccttc ttgctgagaa
     5941 cgacattcaa gtaacccagg caaccctctc acgcgacatc aaaaatatga acctatcaaa
     6001 agtccgcgaa gaagatagcg cttattatgt tcttaacaat ggttccatct caaaatggga
     6061 aaaacgtctc gaactctaca tggaagacgc ccttgtctgg atgcgcccag ttcaacacca
     6121 agtcctacta aaaacccttc ctggactggc tcaatccttt ggttctatca ttgatacttt
     6181 gagcttccct gacgctatcg ctaccctttg tggtaatgat gtctgtctta tcatctgtga
     6241 agatgcagat actgctcaaa agtgctttga agaactgaaa aaattcgccc caccattttt
     6301 ctttgaagaa taataaatga ctacaactaa caattatgct taaaaaaaaa ctggtagaaa
     6361 gtctttaaca tcagaaaacg catagtatca agtgttgaaa acccttgata ctatgcgttt
     6421 tgctttatcc taggaagatt tatactcttc gaaaatctct tcaatccgcg tcaac
//
LOCUS       DAVAGB010000077         6405 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVAGB010000077 DAVAGB010000000
VERSION     DAVAGB010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6405
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.079"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(<1..226)
                     /locus_tag="VQO19_002007"
     CDS             complement(<1..226)
                     /locus_tag="VQO19_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET1350216.1"
                     /translation="MLSLDQIHLLLNTPEDEFHDFKQKWHHSKTELVRDILNFVNTSH
                     HEDCYIIFGIDNITLDIIGVNNDDNRRNEED"
     gene            588..944
                     /locus_tag="VQO19_002008"
     CDS             588..944
                     /locus_tag="VQO19_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350217.1"
                     /translation="MKRDVRDIRKQFRLTEAEEKQILALMRERGETNFSDFLRKSLLS
                     SDLQKQMETWFALWQSQKLEQISRDVHEVLILAQSERQVTQEHVSILLTCVQELIQEV
                     ANTIPLSKEFREKYMR"
     gene            949..1314
                     /locus_tag="VQO19_002009"
     CDS             949..1314
                     /locus_tag="VQO19_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HET1350218.1"
                     /translation="MEHRYRTNLKKVFLSDSELNQLNINIDQSGCKSFSEYARRTLLD
                     PGMNFITIDTNGYQDLVFELKRIGNNINQIARSVNQSQLISGEELQELKKGIGELIKE
                     VDKEFNLQAQKLKEFHGHH"
     gene            1301..3124
                     /locus_tag="VQO19_002010"
     CDS             1301..3124
                     /locus_tag="VQO19_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002917262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HET1350219.1"
                     /translation="MVITKHFAIHGKSYRRKLIKYILNPEKTNNLALVSDYGMKNFLD
                     FPSYEEMVQMYHENFISNDTLYDFRHDRMEENQRKIHAHHIIQSFSPEDHLTPEQINR
                     IGYETVKELTGGKFRFIVATHVDKDHLHNHIIINSVDSNSDKKLKWDYKVERNLRMIS
                     DRFSKIAGAKIIENRYSHQRYEVYRKTNHKYELKQRLYFLMEHSRDFEDFKKNAPLLH
                     VEMDFRHKHATFFITDSTMKQVVRGKQLNRKQPYTEEFFKNYFAKREIESLMEFLLLK
                     VENMDDLLQKAKLFGLTINPKQKHVSFQFAGVEVKETELDQKNLYDVEFFQDYFKNRK
                     DWQAPETEDFVQLYQEEKLSKEKELPSDEKFWESYQEFKSNRDAVHEFEVELSLNQIE
                     KVVDDGIYVKVKFGIRQEGLIFVPNMQLDMEEDKVKVFIRETSSYYVYHKDAAEKNCY
                     MKGRTLIRQFSYENQTIPLRRKATVDMIKEKIAEVDALIELEVENQSYVTIKDELVHE
                     LAASELRINELQERMSTLNQVAEYLLASVESKQEMKLNLSKLNITENISANIVEKKLK
                     SLGNQLELERGRYEKMVVRLDKFINRLNTGLSKGDGIDFQK"
     gene            3238..4104
                     /locus_tag="VQO19_002011"
     CDS             3238..4104
                     /locus_tag="VQO19_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET1350220.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEEVNELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKFYMEWIKSLIDFYFYGQKEEAITRLENMLPQLNVSDLNYLQVSNTLFN
                     FYYDIEDLERFNEIRDKLEHQVNQLNLNTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKEYRTTYLLADLYLLMGSVSENFSSKSSVKEYFETAHFLYKLEENMSMA
                     LKVEHYFADITE"
     gene            4695..4946
                     /locus_tag="VQO19_002012"
     CDS             4695..4946
                     /locus_tag="VQO19_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000098314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350221.1"
                     /translation="MSSQMKAFLNELQGNMEVVGEFFDNPEKVIRKFGIVGREKEALL
                     IRDLNDMDDYALSIQNSVASPSGAHSSTCHFVRQDLQSA"
     gene            5175..5477
                     /locus_tag="VQO19_002013"
     CDS             5175..5477
                     /locus_tag="VQO19_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350222.1"
                     /translation="MKNKYDVKRIIPDELSESLDIFLKNYSETGLSDYNTYLFYGFIL
                     KSYKLPRENRYSIKLLVKELQNRGLKVTLIINIYYHALNCLALNDGLKIYGEDFLI"
     gene            5474..>6405
                     /locus_tag="VQO19_002014"
     CDS             5474..>6405
                     /locus_tag="VQO19_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HET1350223.1"
                     /translation="MNYEKYLNYLDYETEIEDAYHNLLLEYKISDNFSDEHWLYNLPS
                     NITQSKGFKIHLSASILNANLVAKKFFDFIFSREKKINFKILVSIKELSLQNTGLNGY
                     SQVGKFITIYPKDNKEFQRLLHKLEILYKGVKGVNIPSDFRFQLSEVVYYRYGEFVKD
                     STFKDKRDKKIPSNVNVPIRDYYIPRYNTIPDQYIILEVISKNAKGGVYKVFNTQKRV
                     YSLLKEASDLSLVDFTNRDSVNRLINEREILVELEKEEFTPKVFNDFYIKNSYFVEFE
                     FIIADKLSEYNMVSGSYDWFLTLIDYMEIINSKY"
BASE COUNT         2311 a          872 c         1220 g         2002 t
ORIGIN      
        1 gatcttcttc atttcttcta ttatcatcat tgtttacacc gattatatct aaagtgatat
       61 tatcaattcc aaagatgata taacaatctt cgtgatgtga tgtattgaca aaatttaaga
      121 tatcacgcac caattcagtt tttgaatgat gccatttttg tttaaaatca tgaaactcat
      181 cttcgggtgt attcaatagt aagtgtattt gatctagact cagcattttt atttctccaa
      241 atattagttt acagaaattt tatcatagaa tcagagaaag tcaatcataa ctatattagc
      301 tgtgatacct ttttcaaatc ttccctgtta tcctaatatc attcatagaa aatcaatttt
      361 tgattttcta tgggggtttg ggggcgaagt caccaagtta tcttatcgtt ggctgtcaaa
      421 actagaaagt tttgataggc tggcgatatg atttttggga tattgtggac acaatatctg
      481 agctcgcaaa gccttacaag aatgaaaatc agttgttgga aaagtgtact gacattgtat
      541 ggtagctcac attgtcagta caagtatttt ggaaaggaag tagcagtatg aaacgagatg
      601 tgcgtgatat tcggaaacaa tttcgtttaa cagaagcaga agaaaagcaa attctagctt
      661 tgatgagaga gcggggagag actaatttct ctgattttct tcgtaaaagt ttactttcct
      721 ctgatttaca aaaacagatg gagacatggt ttgccctctg gcaatcccaa aaactagaac
      781 aaatcagtcg tgacgttcat gaagttttaa tcttggcaca gtcagaacgt caagtcaccc
      841 aagagcatgt atctattctc ttaacgtgcg tgcaggaatt gattcaagag gttgcaaaca
      901 ccatacccct cagtaaagaa tttcgtgaga agtacatgag gtaagcacat ggaacatcgt
      961 taccgaacca atctcaagaa agtgtttttg tctgatagtg agttgaacca actaaatata
     1021 aatatcgatc aaagtggttg taaatccttt tctgaatatg cgagacgaac tctactcgat
     1081 cctggtatga attttatcac gattgacaca aacggttacc aagatttagt gtttgagtta
     1141 aagaggattg gcaataatat caaccagatt gctcgaagtg ttaatcaatc tcagttaatt
     1201 tctggtgaag aattgcagga gttgaaaaaa ggaattggtg aattgataaa agaagttgat
     1261 aaggaattta atctgcaagc gcagaagcta aaggagttcc atggtcatca ctaaacactt
     1321 tgccattcac ggaaagagtt accgcagaaa gcttatcaag tacattctca atcctgagaa
     1381 aaccaataat cttgccttgg tgtcggacta tggcatgaag aattttctgg actttcctag
     1441 ctatgaggaa atggtgcaga tgtatcatga aaatttcatc agcaacgata cgctttacga
     1501 ttttcgccac gacaggatgg aagaaaatca acgaaaaata cacgctcacc acatcattca
     1561 gtctttctcg ccagaggatc atctcactcc tgaacaaatc aatcggatag gttatgagac
     1621 tgtgaaggaa ttaactggtg gcaaatttcg ttttatcgtt gcgacccatg ttgataaaga
     1681 ccacctgcac aatcacatca ttatcaattc agtagatagc aattctgaca aaaagctcaa
     1741 gtgggactac aaggtggagc gaaatcttcg catgatttct gaccgttttt ctaaaatcgc
     1801 aggtgctaaa atcattgaga accgctattc tcaccagcgg tatgaagtct atcgtaagac
     1861 taatcacaag tatgaactca agcagcgact ctattttttg atggaacatt ctagggactt
     1921 tgaggatttc aaaaagaatg ctccgctact acatgtggag atggatttcc gtcacaagca
     1981 tgccaccttt tttattacgg actcaactat gaaacaggtg gtgcgtggca agcaactcaa
     2041 tcgcaagcag ccttacacag aagaattttt taagaactac tttgccaaaa gagaaataga
     2101 aagtctcatg gaatttttat tgctgaaagt tgagaatatg gatgatttac ttcagaaagc
     2161 aaaacttttt ggactaacta tcaatcctaa acaaaagcat gtttcttttc aatttgcagg
     2221 agtggaggta aaggagacag agctagacca gaaaaatctt tatgatgtag agtttttcca
     2281 agattatttt aaaaatagaa aagattggca agctccagaa actgaggatt tcgttcaact
     2341 ttatcaagaa gaaaagttat ccaaagaaaa agaacttcca agcgatgaga agttctggga
     2401 gtcctatcaa gagttcaaga gtaacagaga tgccgttcat gaatttgagg tggagttgtc
     2461 actcaatcaa attgaaaaag tagtggatga tggaatttac gtcaaggtca agtttggtat
     2521 tcgtcaggag ggacttatct ttgtgccgaa catgcagctt gatatggaag aggataaggt
     2581 gaaggttttc atcagggaaa ccagctccta ctatgtctac cacaaagacg ctgccgagaa
     2641 aaattgttat atgaaaggtc gaaccttaat tagacagttc agctatgaaa atcaaaccat
     2701 tccattacgc agaaaagcga cagtcgatat gattaaagag aagattgcgg aagtggatgc
     2761 tttgattgaa ctggaagtag aaaatcaatc ttatgtcacg attaaagatg agttagtgca
     2821 tgaactagca gcgtctgaat tgagaatcaa tgagttgcaa gaacgaatgt caaccttgaa
     2881 tcaagtagca gaatatctac tggcttcagt tgaaagtaag caagaaatga aattaaatct
     2941 ttcaaaactg aatataactg agaatatcag tgctaatatt gttgagaaaa aattgaagag
     3001 cctggggaat caactggaat tggaaagggg caggtatgaa aagatggtag tcaggctaga
     3061 taaatttata aatcgcttaa atacaggact ttcaaaagga gatgggatag attttcaaaa
     3121 ataggaatct agccaataat tatatacaat gtgtatcttt tgtaaaatat atttgaaatt
     3181 tagatttaat catgttacaa ttaacattga aatcaaatag aaaaggaaga tgcaaacgtg
     3241 ggtacactat tagcaacaag attaaaaaat agacgaaaag aattaaaaat gtctcagcga
     3301 gaattagctg agggtatctg taaacagggg caaattagtc gattagagag tggagagttc
     3361 acccctggag cggatttttt acatgccctt gctaagaaat taaaagttag tatggactac
     3421 ttttttgatg agcaggttgt agaggaagtc aatgagttat cagagtttaa gaagttagca
     3481 cagacattta tcacaaatcg taattatgaa tctttaaaat atatatatga attggaaaat
     3541 gtaaaagccc atcgcttatc tctagcagat aaattttaca tggaatggat aaagtctctt
     3601 atagattttt atttttatgg acagaaagaa gaggcaatta cacgattaga gaatatgcta
     3661 cctcagttaa atgtatctga tttgaactac cttcaagttt caaacactct attcaatttt
     3721 tattatgata ttgaagattt agaacgtttt aatgagatta gagacaagct agagcatcaa
     3781 gtgaatcagc ttaatttaaa cacaattgaa gagttagaac tatcaattaa gttcaattat
     3841 aacgtttgtc gatacctatg gttacagaaa aatattgaag aagctattac gaaaatcaca
     3901 gctacgataa agcaatgtaa ggagtacagg acaacttatc tattagctga tttgtattta
     3961 ttgatgggaa gtgtaagtga aaatttttct tctaaaagtt cagtaaaaga atattttgag
     4021 actgctcatt ttctctacaa acttgaggaa aacatgtcaa tggctttgaa agtcgaacat
     4081 tattttgcag atataacaga ataaggaata cggtgttcta gtgagcatcg ttttttaaat
     4141 ctaatttgaa tacaaaaaag tattaaataa aaaaaaataa aaaaagatta taaaaatact
     4201 tgacaagcta attttgaagt gataaaataa atgcaagaaa acgaaaggag aggtatatga
     4261 gaagtttgtt taggaaaatt gttgctttgt tagtcatagg attaatccta ttagggactg
     4321 ctggaggaac tcaagttcat aagatggcta gagggattga tccaggtcct gcgaatggta
     4381 tttatagata ggagattata gtcacttaaa aatcaaaaaa ttataaaatt tttgttttac
     4441 ttaaatagat attttatgat gggcgaagtt tttataacta gttcctataa gtacagaaac
     4501 ctattttaat ttactaattt caaaacaatt ttttgagata tatgtaatta aatctaaatt
     4561 aagctttaaa aaattatttt tagcaatttg attttgaaag tgtcatgcag caatatgaaa
     4621 gcgtagaata gaggtgtttc caatgtacaa gtaagttttg attccaaata aagtaataga
     4681 aaaggagcta tataatgagt agtcaaatga aagctttctt gaatgaactt caaggaaata
     4741 tggaagttgt tggagaattt tttgataatc ctgaaaaggt aattagaaaa tttggaattg
     4801 tcggaagaga gaaggaagca ttgctaatcc gtgacttaaa tgatatggat gattatgctc
     4861 tttcaattca aaatagcgtt gcatcgcctt ctggggcaca tagtagcact tgccattttg
     4921 ttagacaaga tttacaatcc gcataattgt taatatataa aacataaaat ttcaattttc
     4981 aattagggat aatagaattc cttactatga tatagaaagt gaattaatta ggaaatctta
     5041 gtcagaggtt tctgattaat tcatttttta tatattaaga gtgatgtgaa atgttcaaat
     5101 tgtgagacta ctctcggatt gttgtataga aatttaaaat tttattgtga gctttttaag
     5161 gaagagtggc cgatatgaaa aataaatacg atgttaaaag aattattccg gatgaattat
     5221 cagaatcact agatattttt ctaaaaaatt attctgaaac tggattgtca gattataata
     5281 cttatctctt ttatggtttt atcttgaagt cctataaatt gcctcgagaa aatagatata
     5341 gcataaaatt attggtgaag gaattacaaa atagaggact gaaagttaca ttgattatca
     5401 acatttatta tcacgcttta aattgtttgg ctttaaatga tggtctaaaa atttatggag
     5461 aagatttctt aatatgaatt acgaaaagta tttaaactat ttggactatg aaactgaaat
     5521 agaagacgca taccataatt tattattaga atataaaatt agtgataatt ttagtgatga
     5581 acattggtta tataatttgc cgtctaatat cacccaatct aagggattta aaatacacct
     5641 gagcgcctca atattaaatg ctaatttggt tgctaaaaaa ttctttgatt ttatattttc
     5701 tagagagaag aagataaatt tcaaaatttt ggttagcatt aaagaacttt ctttgcaaaa
     5761 tacagggctt aatggttatt cacaagtcgg gaaattcatt acaatttatc caaaagataa
     5821 taaagagttt caacgtttgt tacacaaatt agaaatattg tataaaggtg taaagggtgt
     5881 aaacatacca tcagatttca gatttcaact tagcgaggtt gtatattaca gatatgggga
     5941 gttcgtaaaa gatagcactt tcaaggataa aagagataag aaaatccctt caaatgtgaa
     6001 tgttccaata agggattact atattccaag atataacact attcctgatc aatatattat
     6061 tttggaagtg atttctaaaa atgccaaagg tggagtttat aaagtattta atactcaaaa
     6121 gcgagtttat tctttattaa aagaagctag tgatttatcg ttggttgatt ttacaaatag
     6181 agattctgtg aatcgtttaa taaatgaaag agaaatatta gtagaattgg aaaaggagga
     6241 atttactcca aaagttttta acgattttta cataaagaat tcgtattttg tggaatttga
     6301 gtttattatt gcagataaat taagcgagta taatatggtt agtggctcgt atgattggtt
     6361 tttaacatta attgattata tggagataat aaactccaaa tataa
//
LOCUS       DAVAGB010000078         6150 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVAGB010000078 DAVAGB010000000
VERSION     DAVAGB010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6150
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.080"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            129..365
                     /locus_tag="VQO19_002015"
     CDS             129..365
                     /locus_tag="VQO19_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HET1350224.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            362..775
                     /locus_tag="VQO19_002016"
     CDS             362..775
                     /locus_tag="VQO19_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HET1350225.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSPSALNMIVNLPEQ
                     FVFGKPLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWISEHSVREKVKK"
     gene            893..1858
                     /locus_tag="VQO19_002017"
     CDS             893..1858
                     /locus_tag="VQO19_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET1350226.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKVQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            1881..2462
                     /locus_tag="VQO19_002018"
     CDS             1881..2462
                     /locus_tag="VQO19_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET1350227.1"
                     /translation="MFEEYPDSVFLDTYIKELRAGKSLAGEENNKNKVLKTGAVSYDY
                     FNSSEVKNLPIDYIPLDEHKVEIGDVIISRMNTSELVGAAGYVWAINSDNIYLPDRLW
                     KVILNDRVNPVFLWKLITNEKTKLKIKRISSGTSGSMKNISKSQLLQIRVPFPPLALQ
                     NEFADFVAQVDKSQFACEIAIKVWRNSLKFSII"
     gene            2492..5842
                     /locus_tag="VQO19_002019"
     CDS             2492..5842
                     /locus_tag="VQO19_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET1350228.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIEQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
BASE COUNT         2078 a          951 c         1249 g         1872 t
ORIGIN      
        1 gcaatccaaa aatctctgga agaacttgaa actttgaaga aatctctgat gcaggagtat
       61 tttggctgat attctgccat tgtaattacg gtaatgattt gttataatac ttcaaaggag
      121 gaaatcagat ggtagtaaaa acaagaaaac aaggaaattc aatcaccatt acgattccaa
      181 gtgaatttaa tattccaagt ggtgttaaat acgaagcgaa attgttacca agtggtgaga
      241 ttatctttac tcctgaagaa ttggggcagc aggtttctta tgtatctgat gatgcctttg
      301 acttaaattt agataaaata tttgacgaat acgacgatgt tttcaaagct ttggtggaaa
      361 aatgacaatc tatttgacag aaaagcaaat tgaaaaaata aatgctttag caattcaacg
      421 gtattctcca aatgagaaaa ttcaaacagt tagtccttct gccttaaata tgattgtgaa
      481 cttaccagaa caatttgtct ttgggaagcc tctttatcca acaatttttg ataaagcaac
      541 gatactattt gtccaattga taaagaagca tgtttttgct aatgctaata aaagaactgc
      601 tttcttcgtt ttggtcaaat ttttacaatt aaacggctat cgtttttctg taacggtaga
      661 agaagcagta aaaatgtgtg taaccatcgc agtagaagct ttaactgatg aaaaaatgac
      721 aagctactcc aaatggattt ctgaacattc tgttagagaa aaggtcaaaa agtaacctag
      781 tatgctggat ttgaatgagc acaagaaaat aaatgaacag acaatattag aattctgtaa
      841 tgcagaaact gatattgtct ctttttattg atgaataaga aagtgagaaa ttatggaatc
      901 aaaagttaca attatcatgc aagaaatgtt acctctttta aataatgaac aattactagc
      961 gttgagagag agtttagaac atcatctagt agacggaaaa aagcagcaga agtattcgaa
     1021 taataacctg ttgcaactat ttattaccgc caagcaggta gagggctgta gctcaaaaac
     1081 aattcgttat tatcagagga cgattgaaaa cttgtttaat gctattaaag agtctgtgac
     1141 acaactcaca acagatgatt taaggagtta tttagcaaat taccagtctg aaaaggattg
     1201 tagtaaggca aatttagaca atattaggcg tatattgtct tctttttttg cttggcttga
     1261 gcaagaggaa tatatcatta aaaatcccat tcgacggata aagaaaatta agactgagca
     1321 aaatgtgaag gaaacttata ctgatgaaca tttggaaatt atgcgtgata actgtgaaaa
     1381 tttgagagat ttggcaataa tagacctact agcatcgaca ggtatgcgtg taggggagct
     1441 tgtacagttg aatcgttcag atattgattt tgaaaacaga gagtgtgttg tctttggtaa
     1501 aggaaagaag gagagaccag tatattttga cgctcgtacg aaaattcatt taagaaatta
     1561 tcttaacgac agaaaagata gtcaccctgc tctttttgta acgctagttg gaaaagtcca
     1621 gaggcttgga attgctggtg tagagattcg cttaagaaag ttaggagaca aactcggcat
     1681 acaaaaggtt cacccacata agttcagaag aactttagcg actaaggcaa ttgataaagg
     1741 tatgcctatc gaacaagtcc aaaaactgct aggtcatagc aagattgaca caaccttggc
     1801 ctatgccatg gtcaatcaaa ataatgtcaa gcattcacac caaaaattca tctcttaaaa
     1861 gcaaatcccg atttaacgag atgttcgaag agtatcctga ctcagtattc ttagatacat
     1921 atataaaaga actaagagca ggtaaaagtt tagctggtga ggaaaataat aagaataaag
     1981 tattaaaaac aggagctgta tcgtacgatt attttaattc atctgaagta aaaaatttac
     2041 caattgacta tattccctta gatgaacata aagttgaaat aggggatgta attattagtc
     2101 gtatgaacac ttctgaacta gttggggctg ctgggtatgt ttgggctatc aatagtgata
     2161 atatatattt gccagataga ttatggaagg ttattctgaa tgatcgagta aatccagttt
     2221 tcttatggaa gcttattaca aatgagaaaa caaaattaaa aattaagaga atttcctctg
     2281 gaactagtgg gagtatgaaa aatatttcga aatcacaatt gttacaaatt agagttccct
     2341 tcccccctct agccctccaa aatgagttcg cagactttgt agcccaggtc gacaaatcac
     2401 aatttgcttg tgagatagct ataaaagtgt ggagaaatag cttgaaattt agtataatat
     2461 agctaaacta tttgtttaaa gtgagaaaaa aatgggaaat tttagctttc ttttaaaaaa
     2521 tgacgaatat gaatcttttt caaaaccttg cattgaagct gaaaatatga ttgctacatc
     2581 aactgtggct actgccttta tggcgcgtcg tgctttggag caggctgtcc attggatata
     2641 tagtcacgat tcatatttag aagctcccta tcgtgctact ctatcttctt tagtatggga
     2701 tgatgatttt agggatatcg tagattctga actccacaag cagatagttc tgttgattcg
     2761 gtggggaaac catgctgctc atggtggtga aattaaggaa cgagaagcga ttttagcttt
     2821 acatcatttg tatcagtttg ttaattttat cgattattgt tacagcaatg aatttgtgga
     2881 gcgttatttt gatgagaagt gcttaccact ttcagcaaac atcaaatacc gagaaactcc
     2941 acaatctatg ataaagttac aagacagttt accagaactg cctgattttc atgaacagat
     3001 ggctgctcag tccgtagaag ttcaagagac ttatactgaa aaacgtgaga ctgcagcgca
     3061 acggcaagat gtgcctttcc atattgaaca attatctgag gcagagacaa gaaagctctt
     3121 tattgatatc gatctccgtt tagcaggatg gatatttgaa gaaaactgtc gtgttgagat
     3181 agccgttgat ggtctcaagc acggttcagg aattggttac tgtgactatg tactttatgg
     3241 taaaaatggg aaaattttag cgattgtaga ggctaaaaaa gcctctgtca atccagaagt
     3301 aggggaagta caggtcaaag aatatgctga agctcttgag aaacatatcg gctatcagcc
     3361 aatttgcttt attacaaatg gcttgaagca ctatatactt gatggtccga accgccgcca
     3421 gattgcaggc ttttactctc aagaagaatt gcaattagtg atggatagac gtcatcttca
     3481 aaaaccactt gaggatattt ctagtaaaat tagggacgat atttccgggc gtcactacca
     3541 aaaacacgcc attgcaagcg tttgtgaagc tttctctaat catcgtagac aggcactttt
     3601 ggttatggca actggggctg ggaaaactcg tacagcagtt tctctagttg atatcttatc
     3661 acgtcataac tgggtaaaaa acgttctctt cttagccgat agaacttcct tggttaagca
     3721 agcctatgat tcgtttagaa aattactccc agatctttcc gtttgtaact tcttagaaga
     3781 taaagaagga gctcaatcaa gtcgcatggt cttttcaact tatccgacca tgattggagc
     3841 gattagtggt caagaagaag taaatcaacg ccctttcact gttgggcatt ttgaccttat
     3901 cataattgac gaatctcacc gttctattta tcagaaatac aagtccattt ttgattattt
     3961 tgatgcaaga attgtaggct taacagctac tccgcgtcaa gatttagata aaaacaccta
     4021 tggattcttt aatttggaga atggggttcc aacatatgca tatgatttgg aagaggctgt
     4081 taaagacgga tatttagtag cctatcattc tatcgaaacc aaactgaaac tacctacgga
     4141 tggtctacat tatgatgatt tgtccgaaga agaaaaggaa cattttgata gcaaatttga
     4201 agacgatagc tgtgaaaaag atattgatgg gagtgtgttt aattccttta ttttcaataa
     4261 aagtacagta gaaattgttt taaatgaact catgacaaga ggaattcaga cagcctcggg
     4321 tgatgaaatt ggtaaaacta ttatttttgc taaaaatcat gaccatgcgg aatatatcag
     4381 aggtattttt aacaaccgct atcctgaaaa agggagcgac tatgctcagg tgattgatta
     4441 tagtattaag cattatcaga ccttgattga tgattttaaa attaaggaga agtatcctca
     4501 aattgcgatt tctgtcgata tgttagatac aggtattgat gtaccagagg ttgttaattt
     4561 agtcttcttc aagaaagtac gctctaaaac taagttttgg cagatgattg gtcgaggaac
     4621 ccgtctatgt aaagatttat ttggacctga gcaggataag gaaaacttct tggtatttga
     4681 ttatggggac aattttgatt attttcgtgc agatccaaga gatggagagg gtcgtcacat
     4741 tgtttcgctg actcagcgtt tatttaatat caaagtggac ttgattcgag aacttcaggg
     4801 actccaatac caagaagatc agtttgcgag agcataccgt cagcagcttg tctcggaact
     4861 tcaaggtcgt atagagagct taaatgagtt ggacttcagg gttcgtatgg ttttagatac
     4921 agtttatagc tataggaaat tggaaagttg gcagaatcta actgctgtta caagtgaaac
     4981 cattcaaaaa aatctctctc cgcttttatt tgatgaagat aaagaagatg agatggcgag
     5041 gagatttgat ttgtggttgc ttcatattca gttggggcaa ctgacagcta aatcttccac
     5101 tgttcatatt tcccaagtga tgaagacggc tagagctctt tctgctattg gcaatatccc
     5161 gcaggttttt gagcaggctg aaattatcag gaaagtacag gagcctgaat tttggaaaga
     5221 agttaacttg tctgatttgg aaaaaattcg tcttgctatt cgagatttat tacagttttt
     5281 ggataaaaca gaccgtaaac cctactatgt taactttgaa gatcgtatac tctccactgt
     5341 tcacgagacc acagcatttt tgcaggtcaa cgatcttcgg tcttacaatg aaaaagttga
     5401 gcattatttg aaaactcatc tggatgagga gtccatttct aagctatacc ataataaaaa
     5461 gttgacatct gatgatatgc ttgcacttga aaaattgctt tgggaaaaat taggtagtaa
     5521 agcagactac caaagtcatt atgaaaataa ggcaattccg agattggttc gtgagattat
     5581 tggtttagat agagagtctg ccaatcgtat tttttctaaa tttttgtcgg atgagaatct
     5641 taatgccagg cagatttcat ttgtaaaatt gattgtagac tacattgtag aaaatggttt
     5701 tttagagacg aaagtgttaa cgcaagagcc gtttaaatct tatggatctg ttcaactact
     5761 cttccaacac caactaccag tacttcgtaa tattgttcaa atcattgaac ttatcaataa
     5821 tcgagctgga gaagcggctt aaattctaaa gtgattgcca tgctgagact catttaaaat
     5881 taaaaagagt agaaatttat gctatatatg agaagtttta ttaggaagaa tgtcatcgtt
     5941 ttcctagaat acagtatcag ttgttaagtg gttgataaat ttcaaagtag atacttgtac
     6001 cacgatgttt gttgatcgag ttattaacaa aagagctact ttgattttaa agaaatagaa
     6061 aacaaaaagc tgagcaagaa ttcaattgca ggagaaaatg aaataatact caatgaaaat
     6121 caaagagcaa actaggaaac tagctgcagg
//
LOCUS       DAVAGB010000079         6123 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVAGB010000079 DAVAGB010000000
VERSION     DAVAGB010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6123
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.081"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            <1..744
                     /locus_tag="VQO19_002020"
     CDS             <1..744
                     /locus_tag="VQO19_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M26"
                     /protein_id="HET1350229.1"
                     /translation="NQYLTDPADGNDVYATNVVKNLTEDEAKKLTSFDSLIDNNILSA
                     REYKAGTYERNGYFTIKLFAPIFSALSGEKGTPGDLMGRRIAFELLAAKGFKDGMVPY
                     ISNQYEEDAKQQGQTINLYGKERGLVTDELVLKKVFDGKYKTWAEFKTAMYQERVDQF
                     GNLKQVTFKDPTKPWPRYGTKTINNVDELQKLMDEAVLQDAKERNYYYWNNYNPETDS
                     AVHKLKRAIFKAYLDQTNDFRRSIFENKK"
     gene            788..6112
                     /locus_tag="VQO19_002021"
     CDS             788..6112
                     /locus_tag="VQO19_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET1350230.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGTSTYHYLDYS
                     TLTQTERVQLKQGRPDESKESYALVYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DKKRKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVDYLELDDR
                     TVSPVEQPKVVTDKGEPEVQPALPEAVVTGKGKTEVQPTLPEAVVTEKGEPEVQPVLP
                     EAVVAEKGEPEVQPALPEAVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPV
                     GTTGVDENRNLIEPPVNDIPEYTEPISTVSEVASEREELPSLHTDIRTETIPKTTIEE
                     SDPSKFIGDNSVKQVGEDGERQIVTSYEELHGKKISESVETVTILKEMKPEIIVKGTK
                     ERPKEKTAPVLTLTKVTEDAMNRSANLNYELDNKDNAEISSIVAEIKDGDTVVKRVDL
                     SKEKLTDAVQNLDLFKDYKIATTMIYDRGQGSETSKLDERPLRLELKKVEIKNIASTN
                     LVKVNDDGTETPSDFMNEKPSEEDVKKMYLKITSRDNKVTRLTVDSIEEVTEEGQKLY
                     KITAEAQDLIQHTDPTKVRNKYVYYIEKPHPKEDNVYYNFKDLVDAMNTDKNGTFKLG
                     ADLNATGVPTPKKWYVDGDFRGTLKSVEGKHYTIHNTERPLFQNIIGGTVTKVNLGNV
                     NINMPWADRIAPIADTIKGGAKIEDVKVTGNVLGRNWVSGFIDKIDNQGTLRNVAFIG
                     NVTSVGDGGQFLTGIVGENWKGLVERAYVDANLIGKKAKAAGIAYWTQNSGDNHKVGV
                     EGAVKKGIVKGTIQVESPVEVGGAVGRLSHHGYIGEVVSMMKVKKGEIFYGSSDMNDD
                     PYWVANNVRGNYVVNGVSEGTISYARAKEHHRIKPISQSEADTKIMMLGITAQDFAIN
                     EPVVNRLNRLTRKEDEYKSTQDYKVDRDLAYRNIEKLQPFYNKEWIVNQGNKLAEDSN
                     LAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGTKEEMDVTKNADSKVKQVREYTIA
                     GQNVVYTPNMVEKDRNQLIQDIKDKLASVQLISPEVRALMDARKKPEENTDERKNGYI
                     KDLYLEESFAETKANLDKLVKSLVENADHQLNSDEAAMKALVKKVDENKAKIMMALTY
                     LNRYYDIKYGDMTIKNLMMFKPDFYGKSVDLLDFLIRIGSSERNIKGDRTLDAYRDMI
                     GGTIGKSELHGFLDYNMRLFTNDTDLNDWFIHAAKNVYVSEPQTTNPDFVNKRHRAFD
                     GLNNGVHNRMILPLLTLKNAHMFLISTYNTMAYSSFEKYGKYTEEARNEFKKEIDKVA
                     HAQQTYLDFWSRLALPSVRDQLLKSENRVPTPVWDNQNYSGIKGINRMGYDEKKVPIA
                     PIRELYGPTWKFHNTNWNMGAMASIFPNPNNNDQVYFMGTNMISPFGISAFTHETTHV
                     NDRMLYFGGHRHRQGTDVEAYAQGMLQTPSSIGHQGEYGALGLNMAYHRENDGDQWYN
                     YDPDKLQTREDIDRYMKNYNEALMMLDHVEADAVLPQLNGDNSKWFKKIDREIRRNLG
                     DGLNNLVAPHQWDNVRDLNQEESSKKLSSINDLIDNNFMTKHGNPGNGRYRPEDFRPN
                     SAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGYYGYDKGFTSYVSSKYQGEADK
                     QNQGRLGDDFIIKKVSNNQFSNLEDWKKYWYHDVKSRAEKGFTEITIDGQTIHNYNEL
                     KDLFDKAVTEDLKKAGNYSNTENLKSKVFKALLKNTDGFFNPLFKKDI"
BASE COUNT         2171 a          954 c         1291 g         1707 t
ORIGIN      
        1 aaccaatatc taacagatcc tgctgatgga aatgatgttt atgctactaa tgttgtgaaa
       61 aatttgactg aagatgaagc taaaaaattg acgagctttg atagtttgat tgacaataac
      121 attctttcgg ctcgtgagta taaggctggc acttatgaga gaaatggcta ctttactata
      181 aaactctttg caccaatctt ttcagcattg agcggtgaga aaggaactcc aggtgacctt
      241 atgggacgaa ggatagcttt tgaacttcta gctgctaaag gatttaaaga tggtatggta
      301 ccatatattt ccaaccaata cgaagaagat gctaaacaac aagggcaaac tatcaatctt
      361 tatggtaaag aacggggctt ggtgaccgat gagcttgttt tgaaaaaggt atttgatggt
      421 aagtataaaa cttgggcaga atttaagaca gctatgtacc aagaacgggt ggatcagttt
      481 ggaaacttga agcaggtgac ctttaaagat ccgacaaaac catggccaag atatggcaca
      541 aagactatca ataatgtgga tgaattgcag aaactaatgg atgaagctgt tttgcaggat
      601 gcaaaagaac gtaattatta ttattggaat aactataatc cagaaacgga cagtgccgtc
      661 cataagttga agagagcaat ctttaaagcc tatcttgacc aaacaaatga ttttagaaga
      721 tcaatttttg agaataaaaa atagtgttta ctattaggaa ataaaaagtg aatgtggagg
      781 attagaattg tcattattaa aaaaagataa attttccatt cggaaaataa agggtattgt
      841 tggttcggta ttcttgggga gtcttttatt tgcaccgtca gttgttggta catcgactta
      901 tcattactta gattatagta ctttgacaca aactgaacgt gttcaactca aacaaggtag
      961 acctgatgaa tcaaaagagt catatgcttt ggtttatgaa aaagacgcat taccaaacac
     1021 aggaagttct caatctatta tgactgcatt gggtttgtta gctatcggga gtcttattgt
     1081 gattatcaca aaagataaaa agaggaaaaa aatcgctaca tttttgattg taggggcgac
     1141 aggtttagtt acactatcaa ctgcttcagc acttaatttg aatgctaaca tccatgagtc
     1201 tggacgtgat ggtgtgttgc aaatttctgg ttacagatat gttgattact tggagcttga
     1261 tgatagaact gtttctccag ttgagcaacc caaagttgtg accgacaaag gcgaaccaga
     1321 agttcagcca gcgttaccag aagctgttgt aactggaaaa gggaaaactg aagtacaacc
     1381 gacattacca gaagctgttg tgactgaaaa aggggaaccg gaagtacaac cagtgttacc
     1441 agaagctgtt gtggctgaaa aaggggaacc agaagtacaa ccagccttac ccgaagcagt
     1501 tgtaactgaa aaaggcgaac cagaagttca tgagaagcct gactatacgc aaccaatagg
     1561 tgcaaacctt gttgagcctg aagttcatga gaaactagca tacactgaac ctgtaggtac
     1621 aacaggagta gatgaaaata gaaacttgat tgagccacct gttaacgata ttccagagta
     1681 tactgaacca atatctacag tttcagaagt tgcatcagaa agagaagagt tgccttcttt
     1741 acataccgat attcgtacag agactattcc taaaaccact atagaagaat ctgatcctag
     1801 caaatttata ggcgataatt ctgttaaaca agttggtgag gatggcgaac gtcaaattgt
     1861 tactagctat gaagagttac atggcaaaaa aatcagcgag tcagttgaaa cagtaacaat
     1921 tttgaaagaa atgaagcctg aaattattgt aaaaggtaca aaagaaagac caaaagaaaa
     1981 aacggctcct gttttaacct tgaccaaagt aacagaagat gctatgaatc gttctgccaa
     2041 cttaaattat gagcttgata ataaagataa tgctgaaata tcaagtattg tagctgaaat
     2101 taaagatggt gatacagtag ttaaaagggt tgatttatct aaagaaaaat taactgacgc
     2161 tgtacaaaat ttggatttgt ttaaagatta taagattgca acaacaatga tttatgatcg
     2221 tggtcaaggt tctgaaacgt ctaaactgga tgaaagacct ctgcgtttgg agttgaaaaa
     2281 ggtcgaaatt aaaaatatcg catctactaa tttagtgaag gtaaatgatg atggtactga
     2341 aacacctagt gattttatga atgaaaaacc ttcagaagaa gatgttaaaa aaatgtactt
     2401 aaaaatcact agtcgcgata ataaggtaac tcgtttaact gtagactcta ttgaagaagt
     2461 gactgaagaa ggtcaaaaac tttacaaaat aactgctgaa gcacaagatt tgattcaaca
     2521 cacagaccca acgaaggttc gtaataagta tgtttattat atagaaaaac cccatcctaa
     2581 agaagataat gtctactata actttaaaga tttagtagat gctatgaata ctgataaaaa
     2641 tggtacattt aaacttggtg cagatttgaa tgccactggt gttccaacac ctaagaaatg
     2701 gtatgttgac ggcgacttta gaggtacatt gaagagtgta gaggggaaac attatactat
     2761 ccacaacacg gagcgtccgt tattccagaa tattattggt ggtacagtaa ccaaagtaaa
     2821 tctgggaaat gtaaatatca atatgccatg ggcagaccgc atcgcaccga ttgctgacac
     2881 tattaaaggt ggcgctaaaa ttgaagatgt caaagtgact ggtaacgtat taggtagaaa
     2941 ctgggtatct ggatttattg ataagattga caaccaaggt acactcagaa atgtagcctt
     3001 tatcggaaat gtgacatctg taggtgatgg tggtcaattc ttgaccggta tcgttggtga
     3061 gaactggaaa ggactagtcg aacgtgcgta tgttgacgca aatcttattg gcaagaaagc
     3121 caaggctgct ggtattgctt attggacaca aaacagtggt gacaatcata aagttggtgt
     3181 cgaaggtgca gtcaagaaag gaattgtgaa gggtaccatt caggtagaaa gtcctgttga
     3241 agtcggcggt gctgttggac gtttgagtca tcatggttat atcggggaag tcgtatctat
     3301 gatgaaagtt aagaagggtg aaatttttta tggttctagt gatatgaatg atgacccata
     3361 ttgggtggcg aataatgtac gaggaaatta tgtagttaat ggtgtgagtg aaggtacgat
     3421 atcttatgct cgtgctaaag aacaccatcg tatcaaacca atttcacagt cagaagcaga
     3481 tactaaaatt atgatgttag gtattacagc acaagatttt gctatcaacg aacctgtggt
     3541 caatcgctta aaccgtttaa ccagaaaaga agatgaatat aagtcaaccc aagactataa
     3601 agtagatcga gatctggctt atcgtaatat tgagaaactt caaccatttt ataacaaaga
     3661 atggattgtc aaccaaggta acaaacttgc agaagattca aacttagcta agaaagaagt
     3721 cctttctgtt acgggtatga aggatggaca gtttgtaact gacttatcag atattgataa
     3781 gattatggtt cactatgctg atggtactaa agaagaaatg gacgtcacta agaatgctga
     3841 ttctaaagtg aaacaagttc gtgaatatac catcgctgga caaaacgttg tttatacacc
     3901 aaatatggtt gagaaagacc gtaaccaatt gattcaagat atcaaagata agttggcgtc
     3961 agttcaattg atttctcctg aagtacgtgc tttgatggat gcacgtaaga aaccagaaga
     4021 aaataccgat gaacgtaaga atggttatat taaagacctt tacttagaag aaagctttgc
     4081 tgaaacgaaa gctaatcttg ataaattggt taaatcctta gttgaaaatg cagatcatca
     4141 attaaatagt gacgaagcgg ctatgaaagc acttgttaag aaggtggatg aaaataaagc
     4201 taaaatcatg atggctctga cttatctcaa tcgttactat gatatcaagt atggggatat
     4261 gactatcaag aacttgatga tgtttaaacc tgatttctat ggtaaatcag ttgaccttct
     4321 tgatttcttg attcgaattg gatcaagtga gagaaatatc aaaggtgaca gaactttgga
     4381 tgcttatcgt gatatgattg gtggaactat tggtaagtct gaattacatg gattcttaga
     4441 ttacaatatg cgtctcttca ctaacgatac tgatttaaat gattggttca tccatgcagc
     4501 taagaatgta tatgtatcag aacctcaaac aacgaaccca gattttgtta ataaacgaca
     4561 tcgtgcattt gatggtttga acaacggtgt tcataatcgt atgattctac ctctattaac
     4621 tcttaagaat gcacatatgt tcttgatttc aacttacaat acaatggctt atagttcttt
     4681 tgagaaatat ggtaagtata cagaagaagc tagaaatgaa ttcaaaaaag aaattgataa
     4741 ggttgcacat gctcaacaaa catacttaga cttctggtca cgtttagcat tgccaagcgt
     4801 acgtgaccaa ttactcaaga gtgagaatag ggtaccaact cctgtgtggg ataaccaaaa
     4861 ctatagtggt attaaaggaa taaaccgtat gggttatgat gagaagaaag taccaattgc
     4921 gccaattcgt gagttatatg gtccaacttg gaaattccat aataccaact ggaatatggg
     4981 agctatggca tctattttcc caaatcctaa taacaatgac caagtttatt tcatgggaac
     5041 aaatatgatt agtccgtttg gtatttcagc ctttactcat gaaactacac acgttaatga
     5101 tagaatgctt tacttcggtg gtcatagaca ccgtcaaggt acagacgtcg aagcctatgc
     5161 tcaaggtatg ctacaaactc cgtcaagtat tggtcaccaa ggtgaatatg gtgctttagg
     5221 tttgaacatg gcttatcatc gtgaaaatga tggtgaccaa tggtataact atgaccctga
     5281 taagcttcaa actcgtgaag atatcgatcg atatatgaaa aactataatg aagcactgat
     5341 gatgctagat catgtagaag cagacgccgt acttccacaa ttgaatggtg ataatagcaa
     5401 gtggttcaag aaaattgata gagaaatacg cagaaatctt ggggatggtt tgaataactt
     5461 agtagcaccg caccaatggg acaacgttcg tgacttaaat caagaagaga gttctaagaa
     5521 attatcaagt attaacgatt tgattgataa taatttcatg accaaacacg gaaatccagg
     5581 taacggacgt tatagaccag aggattttag accaaactca gcttacgtaa atgtcaatat
     5641 gatggcagga atttacggtg ggaatacgag tcaaggtgct cctggttcat tatcgttcaa
     5701 acataatgcc ttccgtatgt ggggttatta tggatatgac aaaggtttca ctagttatgt
     5761 atctagcaaa tatcaaggtg aagctgataa acaaaaccag ggtagattag gtgatgattt
     5821 cattatcaaa aaagtttcaa acaaccaatt ctcaaatctt gaagattgga agaaatattg
     5881 gtatcatgat gtgaaatcca gagctgaaaa aggattcaca gagattacaa ttgatggaca
     5941 aaccattcac aactataatg aactgaaaga cttattcgac aaagctgtca cagaagacct
     6001 caagaaagct ggaaactact caaatactga gaatttgaaa tccaaagtct tcaaagctct
     6061 tcttaaaaac acagacggtt tctttaatcc attgttcaaa aaagacattt aaaccccaat
     6121 tat
//
LOCUS       DAVAGB010000080         5965 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVAGB010000080 DAVAGB010000000
VERSION     DAVAGB010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5965
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.082"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            120..1889
                     /locus_tag="VQO19_002022"
     CDS             120..1889
                     /locus_tag="VQO19_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HET1350231.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MIMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGASPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
     gene            1913..3868
                     /locus_tag="VQO19_002023"
     CDS             1913..3868
                     /locus_tag="VQO19_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET1350232.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLTSQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRNLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREKEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            3870..4307
                     /locus_tag="VQO19_002024"
     CDS             3870..4307
                     /locus_tag="VQO19_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET1350233.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKNDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            4369..5505
                     /locus_tag="VQO19_002025"
     CDS             4369..5505
                     /locus_tag="VQO19_002025"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HET1350234.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQVLDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
BASE COUNT         1833 a          994 c         1219 g         1919 t
ORIGIN      
        1 aagccttttt gcccagcctc gtcaaaagta atgttttgac acaaaatctg tgacaaaact
       61 ttagttttaa aggtttttaa ctttgtatat actagtttta agaaaaggag gatgatctaa
      121 tggaagaaaa agtatcattg aaagtcaggg ttcaaaaact agggacatcg ctttcaaata
      181 tggttatgcc caatattgga gcatttattg cttggggagt attgactgcc ctctttatcg
      241 ctgatggcta tctgccaaat gaacagttag ctactgttgt tggtcctatg ttaacgtatt
      301 tattgccaat cctgattggt tacacaggtg gatatatgat ccatggccaa cgtggtgccg
      361 ttgtaggagc tattgctact gttggtgcaa tcacaggttc tagtgttcct atgtttatcg
      421 gagctatgat aatgggccca ctgggaggat ggactatcaa gaaatttgat gagaagttcc
      481 aggaaaaaat tcgtcccgga tttgaaatgt tagttaataa cttctcagct ggtctcgttg
      541 gttttgcatt attgcttttg gctttctacg caatcggtcc agtcgtatcg actcttactg
      601 gagctgttgg gaatggtgtt gaggctattg tcaatgctcg cctccttcct atggctaata
      661 ttatcatcga accggctaaa gtccttttcc tcaataatgc cctcaatcat ggcattttta
      721 ctcctctggg agtagaacag gtagctcaag ctggtaagtc aattctcttc ctattggaag
      781 ctaatcctgg accaggcctg ggaattctat tagcttatgc tgtattcggt aaaggttctg
      841 ctaaatcttc ttcttggggg gcaatggtta ttcatttctt cggagggatt catgaaattt
      901 actttcctta tgttatgatg aagcctactc tatttttagc tgctatggca ggaggtatct
      961 ctggaacttt tacttttcaa ctcttagacg ctggtcttaa atctccagct tcaccaggtt
     1021 ctattattgc gattatggct acggcgccaa aaggtgtttg gcctcatcta aatgttcttt
     1081 taggtgtttt agtggcagca gttgtttctt tccttgtagc agcccttatt cttcatgcag
     1141 acaagtcaac tgaggattcg ctcgaagctg ctcaggcggc tacccaagca gctaaggctc
     1201 agtctaaagg tcagttagta tcaacttctg ttgatgcagt tgtttcgaca gactcagtgg
     1261 aaaaaatcat tttcgcctgc gatgctggta tgggaagctc tgctatggga gctagtattc
     1321 ttcgagataa ggttaaaaaa gcaggtctag agattccagt atctaatcag gcaatctcaa
     1381 atttgcttga tacaccaaaa acattaattg ttactcagga agaactgaca ccaagagcta
     1441 aagacaagag tccaagtgct attcatgttt ctgttgataa tttcttagcg tcccctcgtt
     1501 atgatgaaat tgtagcttca ttaacaggag cttctccaat agcagaaatt gaaggagata
     1561 taccaacttc agcaccagta gatagtcagg aaattgacct taaccatatt gatgctgtag
     1621 tagttgctta tggtaaagca cagggaactg caactatggg ctgtgaaacg attcgggcta
     1681 tctttagaaa caagaatatt cgtattccag tttctactgc caaaatttca gaattaggtg
     1741 aatttaattc taaaaatata atgattgtaa caactatttc tttacaggca gaagtgcagc
     1801 aagcagcacc gaattctcaa tttcttattg tggatagttt agtaacaaca ccagaatatg
     1861 acaaaatggc tgctagaatg tacaaataga actagaggtt tctaaattac gaatgctatt
     1921 aaccaaacga gaagaacaat tattgaaggc tttcctacat gtagggaagc tttcaatgca
     1981 agatatgact gaaatcttac aggtttcatc tagaacaatt tatcgaactt tatcagattt
     2041 gacagatagc atggagcaat atggaatcga aataacaaag catgggaaat actatatttt
     2101 gactggagag ttggatgatt tgccgacaga acttgaagtg ttagttgagt atagtcccca
     2161 agaaagacaa gagttgatta cctatcgcct tctgactgag agtggttttg tcaccaatga
     2221 agcattgcaa gagtgcacga aagtcagtaa tgtaactatt attcaggata tttcagatat
     2281 tgataagcgt cttttagact ttgatctgaa aattgaacga caaaaaggtt atcggatttc
     2341 tggtgattca gttggtaaga gaagattttt ggctatttta ctgacaaact gtatctcagt
     2401 agcagatttt tcaaccggta attttgggag ctttgatatt ttagaagcag atagaactag
     2461 gctgaccagt cagattgtta ataagcaact gtcaggtttt ccagatatgg atgctaggat
     2521 gaagatgttt tttgcgatct tgttatctct tataggtcag gagcaaaaca ttgaaaattc
     2581 acctaatact agtaagcagg ctttggaaat ttctcaaaaa atttttcaag cttactctaa
     2641 gcagactgca caattttata gtattcagga aattatctat tttgcgagca tcttggatga
     2701 attaatcatt aaacgtcagg acaatccgct ctttacggag aaatttgatg gtgaattttt
     2761 ctacaatatt tcaaatctga ttgatacggt ttccatgtat accaagattg acttttttaa
     2821 ggacaaggtt ttattcaatt ttcttttcca tcatattcgg ctcagtttag gcgtccctat
     2881 cctttttcag ggtgaaaatt tgccagaatc tgtccagatt ttagttgaaa ggaataaatt
     2941 tctttataca gtcatcagtc ttttagtgaa tgatattttt ccgaaatatc ttcatacaga
     3001 gtatgagtat ggcatgattg ccctacattt tatctctagc ttaggccgta gtccagagat
     3061 ttatccagtc cgtgttttgc ttttaacgga tgaacgtcgg gtcactagaa atttattagt
     3121 cagtaaaatt aagagtgttg ctccttttgt agagttgata gatattcagt ctctagtaga
     3181 ttaccacagt attgatctca gtcagtatga ttatatttta tctaccaagc cgctgactaa
     3241 tcaggaaatc gatgtaattt ctagttttcc aaccgtcaaa gaattgcttg aattacagga
     3301 acgacttcag tatgtacagg cacatcgtac aattgtcgcg cgtgatgcta tcgctccaga
     3361 gaaaagttat gacttgcaag attatttaat atctagtagt cagcttttga gtcaattcga
     3421 gttggttcaa ttggagaata atcaatcatt tgagcatacg gtagaacaaa tcatccaata
     3481 tcagaagaat gtgagtgaca gagattacct aacaagaaaa ttgttatctc acttccagaa
     3541 tagtcctatg gctattccta atactggtct ggtgctttta catagtcagt ctagcaaagt
     3601 aacaacaaat agttttacta tgtttgaact caaactacct atctccgcat tgtcaatgaa
     3661 acgagagaaa gaagaggtca aaaggtgtct gctaatgcta atgtctaaag aagctagcga
     3721 ggaagcgaga gatttaatga cagctatcag tcagtcgatt attgaaaatc atctttatac
     3781 agagatttac aagacgggaa atcaatccat tatttatcag atgctaaata ctatttttaa
     3841 cgaaaaaatt aagaaattgg agaactaata tgaaacttga aaaacatttg attaagctta
     3901 ataaacaatt ttctaacaag gaggaagcta tttgttattg tgggcaagtt ctttatgagg
     3961 gtggatatgt taatgaagac tatattgaag ccatgattga gcgagataaa gagctatctg
     4021 tttacatggg taactttatc gccataccgc atggaacaga tgcagcaaaa aatgatgtcc
     4081 tcaagtctgg tattacagtc gttcaagtcc ctagaggggt tgattttggg aatgtatcta
     4141 accctcaagt ggcaacggtt ctttttggta ttgctggtat tggtaatgaa cacttagaaa
     4201 ttattcagaa aatttctatc ttctgtgcag atgtggataa tgttcttaaa ctagcagatg
     4261 ctcagtcaaa agaggaagta ttgcgcttat ttgatgctgt tgaataattg aatttcgtca
     4321 tttgtcatct agtatatatg tccctcaaat aggaaaagga gaaattgaat gaaacattct
     4381 gttcattttg gtgccggtaa tatcggtcgt ggttttatag gtgaaattct atttaaaaat
     4441 ggtttccata ttgattttgt ggatgtcaat aatcagataa ttcatgctct aaatgaaaag
     4501 ggcaagtatg aaattgaaat tgcacagaaa ggacagtctc gtatagaagt aactaatgtg
     4561 gctggcatta atagcaaaga acatcctgag caagtcattg aagcgattca aaagacggat
     4621 attattacta ctgcaatcgg acctaatata ctccctttta tcgctgaact tctagccaaa
     4681 ggaatcgaag ctcgccgagt tgcagggaat acacaggtat tggatgttat ggcctgtgaa
     4741 aatatgattg gcgggtctca atttctttat caagaagtca agaaatattt aagtccggaa
     4801 ggtttgacat ttgctgataa ctacataggt tttccaaatg ctgcagtaga caggattgtt
     4861 ccagcacaaa gtcacgaaga ttcccttttt gttgtggtcg agccctttaa tgaatgggtc
     4921 gtggaaacca agcgtcttaa aaatccagat ttacgtctaa aagatgtgca ttatgaagaa
     4981 gatttagaac cctttattga gcgaaaactt ttttcagtca attctggaca tgcaacttca
     5041 gcttacattg gtgcgcatta tggtgccaag acaattttgg aagctcttca aaatcctaat
     5101 atcaaatctc ggattgaatc tgtattagct gaaattcgga gtctcttgat tgccaaatgg
     5161 aactttgata aaaaagaatt ggagaattat cacaaagtca ttatagaacg atttgaaaac
     5221 cctttcatag tggacgaggt tagtcgcgta gctcgtactc caatccgaaa attaggctat
     5281 aatgaacgat tcatccggcc gatacgtgaa ttgaaagaac tcagtttgtc atataaaaac
     5341 ctacttaaaa cagttggcta tgcctttgac tatcgcgatg taaatgatga agaaagtatt
     5401 cgattaggtg aattgttggc taaacaatca gtcaaagatg ttgttataca agttacaggt
     5461 ttagacgacc aagaattgat tgagcaaatt gtagagtata tttaatattt ttcgaaaatc
     5521 tcttcaaatc aggttagcat cgctttgtct taggcatatg ttactgactt cgtcagttct
     5581 atctacaacc tcaaaacact gtttgagtta tctgcggtaa tctttctagc ttgtctttga
     5641 tttttgttgt tatttataag gtaaaagaag ctggacaaaa agtcttcaaa atcggaaaaa
     5701 ggcagcctat cgggtgttca aaaatcttga taggatgtcc tttattatgg aaagccttat
     5761 tggattttct cctcagattg agtttttgat cagctttatg agataggttt tgctagagat
     5821 gtagcccatc atgttatttt tatggacggt gggaaaattg ttgaaaaaaa taatgcccat
     5881 caattcttta gtcgtccaag agaagaacga accaagcaat tttggaacga attctttcga
     5941 atgcgatcta tatagtaaaa tgaaa
//
LOCUS       DAVAGB010000081         5638 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVAGB010000081 DAVAGB010000000
VERSION     DAVAGB010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5638
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.083"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(198..1166)
                     /locus_tag="VQO19_002026"
     CDS             complement(198..1166)
                     /locus_tag="VQO19_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET1350235.1"
                     /translation="MDIDTSRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGRVMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLAD
                     RWKKHTDGNWYWFDNSGELATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AKEGAMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(1170..1502)
                     /locus_tag="VQO19_002027"
     CDS             complement(1170..1502)
                     /locus_tag="VQO19_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HET1350236.1"
                     /translation="MQQITEIITNGAISILVVLAGVVVRAVKEYLVKKGGEKTIKIVE
                     ILAKNAVHAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            complement(1506..1922)
                     /locus_tag="VQO19_002028"
     CDS             complement(1506..1922)
                     /locus_tag="VQO19_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HET1350237.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALALIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFVFLHSIYLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            complement(1932..2282)
                     /locus_tag="VQO19_002029"
     CDS             complement(1932..2282)
                     /locus_tag="VQO19_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350238.1"
                     /translation="MAETIQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQLKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTDPTVKPKE"
     gene            complement(2285..2488)
                     /locus_tag="VQO19_002030"
     CDS             complement(2285..2488)
                     /locus_tag="VQO19_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350239.1"
                     /translation="MNTEQLNQALQMTIREMSTTSTDSMIASNFLSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            complement(2469..3850)
                     /locus_tag="VQO19_002031"
                     /pseudo
     CDS             complement(2469..3850)
                     /locus_tag="VQO19_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
BASE COUNT         1438 a         1318 c         1031 g         1851 t
ORIGIN      
        1 aaataccttt acatcgtttt actatatctt acaatacctt ttaaaacagc tatattttga
       61 gcttttaaat aaatgttttt acatcatttt acagagattt acgacacttt tgcccctttt
      121 ttgccccttt tttaaaacaa aaaaaccgca agcctaagcc tgcggtgaaa gaacaattta
      181 gaaagtttcc tttctattta tttaactgta atcaagccat ctggctctac tgtgaactct
      241 ggcttatctg ccagtgttcc gtctggtttg aggtagtacc agcctgttcc gtccgctgac
      301 tggataaagg catttgatac catggcgcct tctttggcgc cttctttagc gtctaagtag
      361 taccaagtgt ccttgtactt gacccagcct gtcttcatgg caccttctac atcaaaataa
      421 taccacttct cagcgatttt cttccagcct gtagccagtt cgcctgagtt gtcgaaccag
      481 taccagttgc cgtctgtgtg cttcttccag cggtctgcaa gcatatagcc tgagccatcg
      541 aaataatacc aggtaccgtt gattttctca aacttatctt ttggataaga gccgtctgag
      601 tgtacgtacc agtagccagt gccatttttc tgccagcctg ttgcagcgct caagccgttt
      661 tcgatgtctt gcttaaactg ctcacggcta atgccccaac ttgcaagata tggataaggg
      721 tcaacgtggt ctgagtggtt gtttggttgg ttattggtac agtattcatg cgtcttgata
      781 cctgccaagt cgtctgtatc aagagtcttc ggcaagcctg cttcgtccgc tagattgcgt
      841 agcaattcga tataaaggcg atagtcagcc ataaactctt ccttagttga atggctttca
      901 atcagttcaa ccgctgcgta actctcagca ttccaaccgc ccccaacatc ccaacttccg
      961 ttgttcacag gtcctacctg catgacacgg ccgttcccaa caacgtgcga gaaaaaacct
     1021 aattctgggt ctttccgcca gtgataatcc gcttcattct gtacggttga gttgcgatta
     1081 cctgttgagt gagcatgtac ttgtcgataa ggctgcaccc caacctgggg caagcctgta
     1141 cgtagtctgc ttgtatcgat atccattccc tatcgtcctt tccatgcgtc attcatctgt
     1201 ttcactgcgg actctacgaa ggtgtctaag tctttgtcag tcatgctaat attgtatttt
     1261 gtaagctcag cacggacttt agcgcgagct tgtgccagtt tttcatctcc cttgtagcca
     1321 gtttcagcag ctacttgctc aacggcatga actgcgttct tggccaagat ttcaacgatt
     1381 ttgatggtct tttctccacc ttttttgacg aggtattcct tgactgccct aactaccacc
     1441 cctgccaaaa cgactaggat gctgattgct ccattagtaa tgatttcagt aatttgttgc
     1501 atttgttatt ctcctttttt cgtatcatca tctttttcaa gtaatcgctg aaatactttt
     1561 acaatcggct gaaaaagagt aacatttcct tttaatttgc ggtaattttc aatgagagat
     1621 tgaaaagtaa atgcgatgta cccgagatag attgagtgca agaatacaaa acctgtcttt
     1681 tcaggcaaca aaacggacgc cggaatgagg atcatcagta agagaacccc tgaaatctta
     1741 cgaaggagcc cgttaatgcc gattttgctc ttgtactcga tgtcaggatt gataatcgcc
     1801 gcaatcgtcc ctgtcacaaa atcaatgatt tccattgaga caatcagtgc tagagcgtac
     1861 aagaccaaac catcttcagt ctgtacgaca cttcttagaa aattgaaaaa ttcaatttgc
     1921 atacacacct cctattcttt aggttttacc gttggatccg tccagtcagg attgccctct
     1981 gcatcaaatt tcatgatata gaattcatga ttcaacagaa cggctacgtt gattgttgcg
     2041 attgtaccac cccactggtt gaatgcccaa acggtttcaa catccttgag ttggcgacgg
     2101 ccatttacga tcacaggacg tttttgaaca tcacgataca tatagaagtc atcgcttaca
     2161 ttcttgcaac gaatgaactc tccattttct ttcatgtagc gcaaagcgct cgcaagatca
     2221 aatggttctg tgatttttgt aaggtctagt aagttatctg tgttttgaat tgtttctgcc
     2281 atgtctattc tcctttgtct gctggtttag tttgttcatc aagcagagct tccagctcat
     2341 ccactcgtgc ttgaagtctt tgattctctt ccctttgctc atttaactga atactcaaga
     2401 aattacttgc aatcatcgaa tctgttgaag ttgttgacat ttcacgaatt gtcatttgta
     2461 aggcttggtt aagctgttct gtgttcattt tctaagttct ccaatctgtg tgttcgtttt
     2521 ctattttcaa gagcaaactc ctgaattgct ttaagtgcga tattggtcaa catgttgtta
     2581 ttcatgctat tgttttctcc attttttcta ttttttgatt taattcttga atagccttga
     2641 ttaagtaagg aactaaagcg gtatagtcaa tatgcagata gccatctgga ttctcaggat
     2701 ctcgtgagac aattcttgga acgatggttt cagcctcttg agctattaga ccaatctcct
     2761 catgtttctt attttcgatg aaatcaaatg caaccattct taatctgttg attttatcca
     2821 aggctttcac agctgtatct gtgatgttct cttttaagcg tctgtctgat ttttgttcca
     2881 tccaatactt cacgctaccg ctaccgacct gattccacca aacaaccgca ttccttccgc
     2941 ctttgggatt ccaaccatca ccaagcacat ctttacttcc aagttcgata ccatttgaaa
     3001 acacaggaga acgagaaaaa gtagtattcc catagaagtt tgctctcgat gaattcgaaa
     3061 aatccacttg atcataaaaa ccgacttcat tcctacagta cattttccca tcagtattga
     3121 cgttccatgc tttaggtccg gcatagttcc aattatttcc ccagttcgcc cagaaggctg
     3181 tccggactcc ataaccagcg ccattcccca tgccaacaga gaactgattg acacccgaaa
     3241 tccagcgacc gccaccctgg tcaaattgac caagtgtgaa tccaccgatt cggccttgat
     3301 aggcttctag gaaggttgag ctagaaatga cggactcaac cttaatagag aagatacgtt
     3361 tagatatcag ttcgtcaata aaagcatcag ttgcagttaa ttttctaata agcgcattgt
     3421 caactttcaa cttctcagca gttaccgctt cagcgtctaa tatcgtagtc gtgaccgaac
     3481 cagcttcaaa attggccgtt ttgagcttat caaccatggc agacttgatg actgctctgt
     3541 caatcagggt ctctccagtg atgtgggtca atttcccaac gaagcggtta tgtccattgg
     3601 cgccaagatt gattccagag atgatatctc cagccgagtt gatgttttca actacccatg
     3661 agccagctag ttgagtcatt tttgtttgcg ttgcttcaag cttcttattc gcatctgcga
     3721 ctgcatcttc tggatgtggt tgccatgttc taggtttata acctttgtac aagtcaactt
     3781 ctgtaatata caaatcagct gttcctgatg atgagccatt gttatcaaaa cgaatgtaag
     3841 cattatccat ttctccggaa ttaaaagtta ctgagacatc ttcgcatcta gaggtagata
     3901 gtttcttgct gctaacaact ttcttaacga ttgtgaatcc atcgctctcg cctgctcttc
     3961 gtcccaaaat ataaacatca tagtttgcta gagcactgtt gttaaatcct ctaaaattca
     4021 gtacatagtc agtatttcgt tcaagattaa aacggtgact atacaaaaaa ttttcgtttt
     4081 tagttgcatt acttaaacgc ataaggtctt tctgcccgtt gtgataaaag ctatgcttaa
     4141 ccaatcttcc taaattttga gttgagcccc attcattcgt agaattttta aaatcactat
     4201 tcttaatgag gttagggccg cttacactat atttcccaac ctcaacctga aacagttgat
     4261 tggtcagagc catgcgagca accttatccg caattccatt ttcagtattg cccaaaatcc
     4321 gctcgtaaag tttactggtt tccttaacac gctgaaagtc agtagtctct acttttcgcg
     4381 ctagttgatt ggtcacattc gcaaattgac tatcagcatt cgctttgttt gccgaaacct
     4441 gatcagatat tctacccatt tgtcgttcag cattatcctt gtttgtagcg acctgagtct
     4501 ttaaatttga aatctgatta tctgcgcctt gtttattact gtttatccga tttgaaagat
     4561 ttgaaatctg agtagtggtt ccttgctcac tgcttgtaag tctatttgaa aggccactga
     4621 tttgaccgcc cacatcttgc ttataagtag ttatctgact tgaaatatcc gtgaacttac
     4681 catctacaga ttgacgatag ctagcgattt gactagcgat gtctttattc gcactagttt
     4741 taacagcttc aatcctctga ttgataccct taacatcttc ttgataagta gccttaccaa
     4801 cgaaatcacg attgaccagc tcacggactg ctgtcgcttg tctcgtgctc tcctcacgag
     4861 tatagcgctg tagggcttcc tgtcgctgac cgtctttatt tacatattcc tgaatagctg
     4921 ataagtcggt tcgcaagccc tgagctgtcc gctcaaaggt agccttagct tcagtaatga
     4981 gaccatcagc gtcctcaggc gcaggactcc agtccgtcgc cacactaccg atttcaacct
     5041 tgattcctgt tacccaagct gtaccgcttg tagcaccttc aagattgaat cgcaatgatg
     5101 tcttcaattg atcaaaattt gttttttcag agtagtcata agtgaatgta atatatttcc
     5161 aatctgccga acctttatac ataccaagcg tagcataatc tggaccactc tgtactccgg
     5221 tctcactatt ttttctaaaa agataatgtt tgaagcaatt aaatacattc caaaaatttc
     5281 gaccttggac tacattttcg tacttgatcc aagcgctaaa agtaactttt tggtacaacc
     5341 ttgagctgaa atctggttca aggttgaacg ttaaagtaga gttgttctct agcctatagc
     5401 attctttttg acctgtgacg tggttttcag gtaatttttc aattacagct ccaaccgtct
     5461 tggattttat ccatagattc cggcctccca ccttcatttt tgaaaattct tcacgcaatt
     5521 tcccggcttc agatacaact aaagtcttat ctgctttatc cttggttgcg ttcaagattt
     5581 cctgacggat agagccggct cgcacctcaa attcagcctg actcaacttc tgatttag
//
LOCUS       DAVAGB010000082         5471 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVAGB010000082 DAVAGB010000000
VERSION     DAVAGB010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5471
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.084"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            1..110
                     /locus_tag="VQO19_002032"
                     /pseudo
     CDS             1..110
                     /locus_tag="VQO19_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            280..480
                     /locus_tag="VQO19_002033"
     CDS             280..480
                     /locus_tag="VQO19_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350240.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKVPEDSALTE"
     gene            505..921
                     /locus_tag="VQO19_002034"
     CDS             505..921
                     /locus_tag="VQO19_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350241.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGLAETETKLVEELKAILDKLK"
     gene            1152..1859
                     /gene="ccdA2"
                     /locus_tag="VQO19_002035"
     CDS             1152..1859
                     /gene="ccdA2"
                     /locus_tag="VQO19_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET1350242.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1870..2427
                     /gene="sdbB"
                     /locus_tag="VQO19_002036"
     CDS             1870..2427
                     /gene="sdbB"
                     /locus_tag="VQO19_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HET1350243.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2801..4192
                     /locus_tag="VQO19_002037"
     CDS             2801..4192
                     /locus_tag="VQO19_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HET1350244.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4335..5252
                     /gene="adcAII"
                     /locus_tag="VQO19_002038"
     CDS             4335..5252
                     /gene="adcAII"
                     /locus_tag="VQO19_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HET1350245.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSILAEELK"
     gene            5260..>5471
                     /locus_tag="VQO19_002039"
     CDS             5260..>5471
                     /locus_tag="VQO19_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET1350246.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIV"
BASE COUNT         1661 a          971 c         1164 g         1675 t
ORIGIN      
        1 gtgaattaat cgctccaatg acttacgaag agatgatgac gagcgacttt tttgaagtat
       61 ggtttcagaa gtttctctta ccaacattaa ccacaccatc ggttattata gcgaaatgaa
      121 ataagaacag gacaaatcga tcaggacagt aaaatcgaat tctaacaatg ttttagaagt
      181 ccatatgtac tattctagtt tcaatatacc ataactgttc ctagtcaacc tgcaagtcct
      241 gtcccagctc caagctcagc tccgactcaa gatcctagag tggtagcaag cgcttcggct
      301 agctcaacga gcacacaagc tcaagagcaa gttgacaagt ctgaacttcg tgccttgagt
      361 caagagttag accaacgctt gaaagctttg gcaacagtat ctgatccgaa aatcgatgca
      421 accaaggctg tcctcctaga tgctcaaaaa gttccggaag atagtgcctt gacagagtaa
      481 ggtctgcata ctgcagtaga gtctgtgaag gctgccttgg actctctcaa agatgtgaaa
      541 gcaaatgcta gcgacagcaa gcctgcacag gacaagaagg atgcaaaaca aggaacggaa
      601 gatagtaagg attcagataa gatgactgaa acaaactcag ttccggcagg agtgattgtg
      661 gtcagtctac ttgccctcct aggcgtgatt gccttctggc tgattcgccg taagaaagag
      721 tcagaaatcc agcaattaag cacggaattg atcaaggttc taggacagct agatgcagaa
      781 aaagcggata aaaaagtcct tgccaaagcc caaaaccttc tccaagaaac ccttgatttc
      841 gtgaaagaag aaaatggctt agcagagaca gaaactaaac tagtagagga gcttaaagca
      901 atccttgaca aactcaagta aaacatgatt tatgaaatgt cagacctaaa agacattttc
      961 gttcacaaaa gcagcgatga gtaatccttg tcgttgcttt ttggctattt tgggggataa
     1021 gatccgcctt gactagcaaa agaaaagatt ggtccaatag tgcccgatac gattttgcgt
     1081 agcagaaagc ttacaaataa aattgaatat agtaaaatag gattagaatt attaagaaag
     1141 ttggttcttt attggaaacg atagtatttt taatctctgt ttttctagca ggtgttttat
     1201 cctttttttc tccttgtatt tttcctcttc tgccagtcta tgctgggatt ttattggatg
     1261 atcaagaaag tgcaaaaagc ttttctttgt ttgggagaaa ggttctctgg tcaggcttga
     1321 ttcgaacact ttgctttatc gctggtatct ctctcatttt ctttattcta ggctttggtg
     1381 ctggttactt tggtcatatt ctctatgcaa attggtttcg atatggcatg ggagctatta
     1441 ttatcatttt gggtcttcac cagatggaaa tttttcattt gaagaaatta gaagttcaaa
     1501 aaagttttac ctttaaaaaa tcagattcta atcgttattg gtcagctttt ttacttggta
     1561 ttacctttag ctttggttgg acaccttgta ttggtccagt tttaagttct gttttagcac
     1621 ttgcggcttc tggaggcaat ggcgcttggc aaggagcgat ttatactctc atttacactc
     1681 tgggcatggc ccttcctttc ttggtattgg cactagcttc aggtctagtc atgccatatt
     1741 ttagtaaaat caagcgtcat atgatgctac taaagaaaat tggtggtttc ctcattgttt
     1801 taatgggaat tttgttacta ttaggacaag taaatgttct agctggaatt tttgaataaa
     1861 ggaggacaaa tgaaaaaagt aatgtttgct ggcttaagtc tcttgtcatt agttgtattg
     1921 atggcctgtg gtgaggaaga aactaaaaag actcaagcag cacaacagcc aaaacaacaa
     1981 acgactgtac aacaaattgc tgttggaaaa gatgctccag acttcacatt gcaatccatg
     2041 gatggcaaag aagttaagtt atctgatttt aagggtaaaa aggtttactt gaagttttgg
     2101 gcttcatggt gtggtccatg caagaaaagt atgccagagt tgatggaact agcggcgaaa
     2161 ccagatcgtg atttcgaaat tcttactgtc attgcaccag gaattcaagg tgaaaaaact
     2221 gttgagcaat tcccacaatg gttccaggaa caaggatata aggatatccc agttctttat
     2281 gataccaaag caaccacctt ccaagcttat caaattcgaa gcattcctac agaatattta
     2341 attgatagcc aaggaaagat tggaaagatt caatttggtg ctatcagtaa tgcggatgca
     2401 gaagcagcat ttaaagaaat gaactagaat cgataaaatc tgattacaag atgtagtcag
     2461 attttggtaa cttctaaaac taacttccag tttcccacaa cctagctttt agtatgagaa
     2521 aaacgcgtga catcagtgga aatccgtctt agactaactt ccactggttt tctttttctt
     2581 gatatataag ggttcaaaag cgaaaagact cagaaaaagt gcacgacaaa tagccctaaa
     2641 acagagtcgt cttagagtaa cttccagttt tgggagagag atggaagtta ctttgagaag
     2701 ttacggtagt cagatttttt tagaaaaaca ttttataaat attcacatat ctcctatatt
     2761 tatggtaaaa tagaattatc agtttatttt ggagtcaaag atgaatatat ttagaacaaa
     2821 gaatgttagt ttagataaaa cagagatgca taggcatttg aagttatggg atttgatttt
     2881 gctgggtatc ggagccatgg tagggacagg cgtctttaca atcacaggta ctgcagctgc
     2941 aacacttgct ggcccagccc tagtgatttc aatcgttatt tctgccttgt gtgtgggatt
     3001 atcagccctc ttttttgcag aatttgcctc gcgagtaccc gctacaggag gtgcctatag
     3061 ttacctctat gctatcttag gagaattccc tgcctggttg gctggttggt taaccatgat
     3121 ggagttcatg acagccatat caggcgtagc ttcgggttgg gcagcttatt ttaaaggctt
     3181 gctctctcaa tacgggatag cctttcctca ggctttaaat ggtaccttta atcctcaagc
     3241 agggacattt gttgatttat tgcctattct tgtcttggtc ttggtgactt cgcttgtttt
     3301 actaaatgcc aaggcagcct tacgctttaa ttcgattcta gttattttga aattttccgc
     3361 tttagctctc tttgttttag taggaatttg gaatattaag tttgataatt ggagcaattt
     3421 tgctccttac ggttttggac aaatctatgg agctagcact ggtattatgg ctggtgcgtc
     3481 cttgatgttc ttcggttttt tgggatttga atccatctct atggctgtag atgaagtcaa
     3541 gactcctcaa aaaaatattc ctagagggat tgtcttatcg ctttctatcg taaccattct
     3601 ctatgccttg gtgacccttg ttttgactgg tgtggttcac tatagtcatt taaatgtcga
     3661 tgatgccgtt gcctttgccc ttcgtagtgt tgggattagt tgggcagcca actatgtgtc
     3721 attagtggct atcttgacct tgattacagt ttgtatttcg atgacctatg ccctatcgcg
     3781 tatgatttac agtttagcac gtgacggctt agtgcctgct gcctttaagg aactgacgaa
     3841 gactagcaag ataccaaaga atgctactat cttgacaggt ctagcttcag cagtagcagc
     3901 aggaatgttc ccactagcca gtattgcagc ctttttaaat atttgtacct tagcctactt
     3961 gatcatgttg gcttatggtc tgattcgctt acggaaagaa aaaggaatgc ccaaagctgg
     4021 ggaatttaaa acaccattgg tacctctgtt accaatttta tcgatcatca tttgtttatc
     4081 cttcatgtta cagtataata tgaatacctg gattgctttc ctagttgcgt tgttagtagg
     4141 aagtattatt tacttcactt atggctataa gcattctacc atagaagaat aaagtgaaag
     4201 tctattgagt tgttgacact cagcagattt ttatatgtga aagaaatttc aaattttttc
     4261 taaaaatatc ttgacagatt aaattttcag gagtagaata tttactagtt aattaaatgg
     4321 ttaaggagtt gttcatgaag aaacaaaatt tatttttagt cctgttaagt gtctttcttt
     4381 tgtgcttggg ggcttgtggt caaaaggaaa gtcagacagg aaaggggatg aaaattgtga
     4441 ccagttttta tcctatctac gctatggtta aggaagtatc tggtgacttg aatgatgttc
     4501 ggatgattca gtcaagtagt ggtattcact cctttgaacc ttcggcaaat gatatcgcag
     4561 ccatctatga tgcagatgtc tttgtttacc attctcatac actcgaatct tgggcaggaa
     4621 gtctggatcc aaatctaaaa aaatccaaag tgaaggtctt agaggcttct gagggaatga
     4681 ccttggaacg tgtccctgga ctagaggatg tggaagcagg ggatggagtt gatgaaaaaa
     4741 cgctctatga ccctcacaca tggctagatc ctgaaaaagc tggagaagaa gcccaaatta
     4801 tcgctgataa actttcagag gtggatagtg agcataaaga gacttatcaa aaaaatgcgc
     4861 aagcctttat caaaaaagct caggaattga ctaagaaatt ccaaccaaaa tttgaaaaag
     4921 cgactcagaa aacatttgta acacaacata cagccttttc ttatctagcg aagagatttg
     4981 ggcttaatca acttggtatt gcaggcatct ctcctgaaca agaaccaagt ccacgacaat
     5041 taacagaaat tcaggaattt gttaaaacct ataaggttaa aacgattttt acagaaagta
     5101 atgcttcttc aaaagtagct gaaactcttg tcaaatcaac aggtgtgggt cttaaaactc
     5161 tgaatccttt agaggcagac ccacaaaatg acaagaccta tttagaaaat ctggaagaaa
     5221 atatgagtat tctagcagaa gaattaaagt gaggaaagaa tgaaaatcaa taaaaaatat
     5281 ctagcaggtt cagtggcagt ccttgcccta agtgtttgtt cctatgaact tggtcgtcac
     5341 caagctggtc aggttaagaa agagtctaat cgagtttctt atatagatgg tgatcaggct
     5401 ggtcaaaagg cagaaaattt gacaccagat gaagtcagta agagagaggg gatcaacgcc
     5461 gaacaaatcg t
//
LOCUS       DAVAGB010000083         5164 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVAGB010000083 DAVAGB010000000
VERSION     DAVAGB010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5164
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.085"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            297..1842
                     /locus_tag="VQO19_002040"
     rRNA            297..1842
                     /locus_tag="VQO19_002040"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1894..1966
                     /locus_tag="VQO19_002041"
     tRNA            1894..1966
                     /locus_tag="VQO19_002041"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1927..1929,aa:Ala,seq:tgc)
     gene            2091..4992
                     /locus_tag="VQO19_002042"
     rRNA            2091..4992
                     /locus_tag="VQO19_002042"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5069..>5164
                     /gene="rrf"
                     /locus_tag="VQO19_002043"
     rRNA            5069..>5164
                     /gene="rrf"
                     /locus_tag="VQO19_002043"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1457 a         1048 c         1513 g         1146 t
ORIGIN      
        1 cgccttttca cggcggtaac acgggttcga atcccgtacg gactatggta tgttgcggtt
       61 ggaacacttg atgaaaaaaa gtttaaaaaa gcttaaaaat cttcaaaaaa gtgttgacaa
      121 gtgaaagtgg ctgtgatata ctaatatagt tgtcgcttga gagaagcaag tgacaaagac
      181 ctttgaaaac tgaacaagac gaaccaatgt gcagggcgct acaacataag ttgtagtact
      241 gaacaatgaa aaaacaataa atctgtcagt gacagaaatg agtgagaact caaactttta
      301 atgagagttt gatcctggct caggacgaac gctggcggcg tgcctaatac atgcaagtag
      361 aacgctgaag gaggagcttg cttctctgga tgagttgcga acgggtgagt aacgcgtagg
      421 taacctgcct ggtagcgggg gataactatt ggaaacgata gctaataccg cataagagtg
      481 gatgttgcat gacatttgct taaaaggtgc acttgcatca ctaccagatg gacctgcgtt
      541 gtattagcta gttggtgggg taacggctca ccaaggcgac gatacatagc cgacctgaga
      601 gggtgatcgg ccacactggg actgagacac ggcccagact cctacgggag gcagcagtag
      661 ggaatcttcg gcaatggacg gaagtctgac cgagcaacgc cgcgtgagtg aagaaggttt
      721 tcggatcgta aagctctgtt gtaagagaag aacgagtgtg agagtggaaa gttcacactg
      781 tgacggtatc ttaccagaaa gggacggcta actacgtgcc agcagccgcg gtaatacgta
      841 ggtcccgagc gttgtccgga tttattgggc gtaaagcgag cgcaggcggt tagataagtc
      901 tgaagttaaa ggctgtggct taaccatagt aggctttgga aactgtttaa cttgagtgca
      961 agaggggaga gtggaattcc atgtgtagcg gtgaaatgcg tagatatatg gaggaacacc
     1021 ggtggcgaaa gcggctctct ggcttgtaac tgacgctgag gctcgaaagc gtggggagca
     1081 aacaggatta gataccctgg tagtccacgc tgtaaacgat gagtgctagg tgttagaccc
     1141 tttccggggt ttagtgccgt agctaacgca ttaagcactc cgcctgggga gtacgaccgc
     1201 aaggttgaaa ctcaaaggaa ttgacggggg cccgcacaag cggtggagca tgtggtttaa
     1261 ttcgaagcaa cgcgaagaac cttaccaggt cttgacatcc ctctgaccgc tctagagata
     1321 gagctttcct tcgggacaga ggtgacaggt ggtgcatggt tgtcgtcagc tcgtgtcgtg
     1381 agatgttggg ttaagtcccg caacgagcgc aacccctatt gttagttgcc atcatttagt
     1441 tgggcactct agcgagactg ccggtaataa accggaggaa ggtggggatg acgtcaaatc
     1501 atcatgcccc ttatgacctg ggctacacac gtgctacaat ggctggtaca acgagtcgca
     1561 agccggtgac ggcaagctaa tctcttaaag ccagtctcag ttcggattgt aggctgcaac
     1621 tcgcctacat gaagtcggaa tcgctagtaa tcgcggatca gcacgccgcg gtgaatacgt
     1681 tcccgggcct tgtacacacc gcccgtcaca ccacgagagt ttgtaacacc cgaagtcggt
     1741 gaggtaaccg taaggagcca gccgcctaag gtgggataga tgattggggt gaagtcgtaa
     1801 caaggtagcc gtatcggaag gtgcggctgg atcacctcct ttctaaggat aaggaactgc
     1861 gcattggtct tgtttagtct tgagaggtct tgtggggcct tagctcagct gggagagcgc
     1921 ctgctttgca cgcaggaggt cagcggttcg atcccgctag gctccattgg tgagagatca
     1981 ccaagtaatg cacattgaaa attgaatatc tatatcaaat agtaacaaga aaataaaccg
     2041 aaaacgctgt agtattaata agagtttatg actgaaaggt cagaaaataa ggttaagtta
     2101 ataagggcgc acggtggatg ccttggcact aggagccgac gaaggacgtg acaaacgacg
     2161 atatgccttg ggtagctgta agtaagcgat gatccaggga tttccgaatg ggggaaccca
     2221 acaggtaata cctgttaccc acatctgtta aggatgtgag gaggaagacg cagtgaactg
     2281 aaacatctaa gtagctgcag gaagagaaag caaaagcgat tgccttagta gcggcgagcg
     2341 aaacggcaga agggcaaacc gaagagttta ctcttcgggg ttgtaggact gcaatgtgga
     2401 ctcaaagatt atagaagaat gatttgggaa gatcagccaa agagagtaat agcctcgtat
     2461 ttaaaatagt ctttgtacct agcagtatcc tgagtacggc gggacacgtg aaatcccgtc
     2521 ggaatctggg aggaccatct cccaacccta aatactccct agtgaccgat agtgaaccag
     2581 taccgtgagg gaaaggtgaa aagcaccccg ggaggggagt gaaatagaac ctgaaaccgt
     2641 gtgcctacaa caagttcgag cccgttaatg ggtgagagcg tgccttttgt agaatgaacc
     2701 ggcgagttac gttatgatgc gaggttaagt tgaagagacg gagccgtagg gaaaccgagt
     2761 ctgaataggg cgccttagta tcatgacgta gacccgaaac catgtgacct acccatgagc
     2821 aggttgaagg tgcggtaaga cgcactggag gaccgaacca gggcacgttg aaaagtgctt
     2881 ggatgacttg tgggtagcgg agaaattcca aacgaacttg gagatagctg gttctctccg
     2941 aaatagcttt agggctagcg tcgacattag agattcttgg aggtagagca ctgtttgggt
     3001 gaggggtcca tcccggatta ccaatctcag ataaactccg aatgccaatg aattatggtc
     3061 ggcagtcaga ctgcgagtgc taagatccgt agtcgaaagg gaaacagccc agaccaccag
     3121 ctaaggtccc aaaataattg ttaagtggaa aaggatgtgg ggttgcacag acaactagga
     3181 tgttagctta gaagcagcta ttcattcaaa gagtgcgtaa tagctcacta gtcgagtgac
     3241 cctgcgccga aaatgtaccg gggctaaaac aatttaccga agctgtggat acctttatag
     3301 gtatggtagg agagcgttct atgtgtgatg aaggtatacc gtgaggagtg ctggaacgca
     3361 tagaagtgag aatgccggta tgagtagcga aagacaggtg agaatcctgt ccaccgtaag
     3421 actaaggttt ccaggggaag gctcgtccgc cctgggttag tcgggaccta aggagagacc
     3481 gaaaggtgta tccgatggac aacaggttga tattcctgta ctagagtatg tagtgatgga
     3541 gggacgcagt aggctaacta aagcagacga ttggaagagt ctgtctaagc agtgaggtgt
     3601 gatatgagtc aaatgcttat atctgtaaca ttgagctgtg atggggagcg aagtttagta
     3661 gcgaagttag tgacgtcaca ctgccaagaa aagcttctag cgtttaaaca tactctaccc
     3721 gtaccgcaaa ccgacacagg tagtcgaggc gagtagcctc aggtgagcga gagaactctc
     3781 gttaaggaac tcggcaaaat gaccccgtaa cttcgggaga aggggtgctg actttaagtc
     3841 agccgcagtg aataggccca agcaactgtt tatcaaaaac acagctctct gctaaatcgt
     3901 aagatgatgt atagggggtg acgcctgccc ggtgctggaa ggttaagagg agtgcttagc
     3961 gtaagcgaag gtatgaattg aagccccagt aaacggcggc cgtaactata acggtcctaa
     4021 ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa tgatttgggc
     4081 actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag gttacccgcg
     4141 acaggacgga aagaccccat ggagctttac tgcagtttga tattgagtgt ctgtaccaca
     4201 tgtacaggat aggtaggagt ctaagagatc gggacgccag tttcgaagga gacgctgttg
     4261 ggatactacc cttgtgttat ggccactcta acccagatag gtgatcccta tcggagacag
     4321 tgtctgacgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga ggcgcccaaa
     4381 ggttccctca gaatggttgg aaatcattcg cagagtgtaa aggtataagg gagcttgact
     4441 gcgagagcta caactcgagc agggacgaaa gtcgggctta gtgatccggt ggttccgtat
     4501 ggaagggcca tcgctcaacg gataaaagct accctgggga taacaggctt atctccccca
     4561 agagttcaca tcgacgggga ggtttggcac ctcgatgtcg gctcgtcgca tcctggggct
     4621 gtagtcggtc ccaagggttg ggctgttcgc ccattaaagc ggcacgcgag ctgggttcag
     4681 aacgtcgtga gacagttcgg tccctatccg tcgcgggcgt aggaaatttg agaggatctg
     4741 ctcctagtac gagaggacca gagtggactt accgctggtg taccagttgt cttgccaaag
     4801 gcatcgctgg gtagctatgt agggaaggga taaacgctga aagcatctaa gtgtgaaacc
     4861 cacctcaaga tgagatttcc catgattata tatcagtaag agccctgaga gatgatcagg
     4921 tagataggtt agaagtggaa gtgtggcgac acatgtagcg gactaatact aatagctcga
     4981 ggacttatcc aaagtaactg agaatatgaa agcgaacggt tttcttaagt tgaatagata
     5041 ttcaattttg agtaggtatt actcagagtt aagtgacgat agcctaggag atacacctgt
     5101 acccatgccg aacacagaag ttaagcccta gaacgccgga agtagttggg ggttgccccc
     5161 tgtg
//
LOCUS       DAVAGB010000084         4747 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVAGB010000084 DAVAGB010000000
VERSION     DAVAGB010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4747
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.086"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(181..1932)
                     /locus_tag="VQO19_002044"
     CDS             complement(181..1932)
                     /locus_tag="VQO19_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1350247.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKKSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGSA
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     TSDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRF
                     YPISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVI
                     AAAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATS
                     SIDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMD
                     RKGKYYQMQKAAAFSSE"
     gene            complement(1934..3658)
                     /locus_tag="VQO19_002045"
     CDS             complement(1934..3658)
                     /locus_tag="VQO19_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1350248.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VLVAILTIVIVGLSRLVNPFYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISVKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYCEIN
                     ASQHGKED"
     gene            complement(3716..4654)
                     /gene="msrB"
                     /locus_tag="VQO19_002046"
     CDS             complement(3716..4654)
                     /gene="msrB"
                     /locus_tag="VQO19_002046"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET1350249.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
BASE COUNT         1412 a         1045 c          981 g         1309 t
ORIGIN      
        1 ctgacttcgt cagtcttatc tacaacctca aagctgtgct ttgagcaacc tacggctagc
       61 ttcctagttt gctctttgat tttcattgag tattacagtg aacaattttt ctagctattg
      121 taacaaaaaa gtcactcgaa ggcaactttt ttcgtccata aactttcaaa agagaatggc
      181 ttattcagaa ctaaaagccg cagctttttg catttggtaa tacttaccct ttctatccat
      241 gagttcttga tggttaccat attcaacaat atcaccatct actaagacaa gaattaaatc
      301 cgcatcctga atggttgaca aacggtgagc aatgatgaaa cttgtgcggc ccttcatgag
      361 ttttgcaaag gcatcctgta ccagcacttc tgtccgtgta tcaatggaag aagttgcctc
      421 gtctaagata agaatctttg gaatagccag aaagactcgg gctatggtca agagctgagc
      481 ttggccgaca gagagagatt ctccagcatt ttccaacttg gtatcgtatc cctgtggcaa
      541 ctgttggatg aaaaagtctg cattagctgc tttggcagca gcaattactt gctctcgact
      601 ggcttcagga ttgccaaagg caatattatc atgaatggtc ccttgtgtga gccaggtttc
      661 ttgaagcacc ataccaaact gctgtctcaa tgatactcgt gtataatcat aaatggattg
      721 cccatccagc aagatatctc ccgagctaat gggataaaaa cgcataagga gattgataag
      781 agttgatttt ccagcacctg tcggaccaac gatggctacc ttactaccag ctggaatatc
      841 gatagacaag tccttaatca aaattttttc aggatggtag ccaaaagaga catgtttaaa
      901 ggaaatagct cccttaactt ggtcactggt cgtcaagact tccttacctg tttcagccac
      961 ttcagggcta tctaagactc catagatacg ctctacgcaa gccagagcac tttgcaactc
     1021 agctagcact gaagaaatat cgttaaaggg cttggtgtat tgctgaacat agttcaaaaa
     1081 agtcactaaa cgaccgacgg tcaaggctga acccatcatg atacgataag ctcctactcc
     1141 agctaaaagg gcataaatga gtgcatttac aaagcgagtc gaaggattga ccgttgaaga
     1201 ataaaagatg gctgactgag aatagcctga gtagttgtca tgagcctcac gcaatctttg
     1261 gataaattct gtttgagcat tgaaggactg gattatagtc tgctgactaa gcgattcttc
     1321 aatcaactga gtctgaattc ccctcgtctc tgtttgcttc tggaagagat gataggattt
     1381 cttggcaata aagcgtgaaa tcaccatgga cagtggcgtc aacagcaaga ctaagagagt
     1441 catgaggaga tgaatttgga gcatggctag aatactgacc aaaatcatca aaacaccaat
     1501 gaaaaattgg ttaaaaatca tggtcaagcc agctgccaac tgttcgatgt ccgtggttac
     1561 acgactaacc atctctccac taccttgcct atctacaaag gcaatcggta aacgatggag
     1621 cttatggatg attcgctccc gtaaatctct ggtataagag aagattagac gattatagag
     1681 gagaggattg gcccattgta ccagagtatt tcctattacc accaagagca tctggagaaa
     1741 aatctgccaa aaaactggtg atgaaccagc cactaggact tggtcaatga cctgcccaat
     1801 cagaataggt aggtaaattg ataagccaac ttgagcaata gttcctagaa aggctaggaa
     1861 aaggaggaaa ggatggcttg ctaaatctac ggctaaacgt ttgagcgtct ggtttacagt
     1921 ttgtcgtttc attctagtcc tcctttccat gttgggatgc attgatttca caatagactt
     1981 ggctggattt catcaagtca tcgtgcttgc caacagctag caactcacct ttttccaaga
     2041 ggagaatctg gtccgccatc tgtaaagttg aggttcgttg agagatcaaa attaagctcg
     2101 tgtttggaaa attttctcta atagctttca agagcttgga ctctgtaatg gtatccagtg
     2161 ccgaggttgc atcatctagg atgagaaacg gagcttggcg caagactgct cgggcgatag
     2221 acaatctttg tttttgtcca cctgagaaat ttcgcccccc tgcctcaact agagcatcca
     2281 agagtccttc cttttcactg acaaaatcct tagcttgcgc aatctccaag gcctgccaga
     2341 gttcctggtc agatacttct tgattgaaac ctagagtcaa gttggaacga atggttcctt
     2401 taaagagttc gaccttttga ggtacatagg caatccaaga ccgccactgc tccaaattaa
     2461 gaggactacg tccattttga taaaggtcaa tgttcccctt gtctactgga taaagtccaa
     2521 gtaagagttg caccaagctt gatttaccag aaccagttcc cccgatgata cctagaattt
     2581 gtccttgagt catatcaaag gaaatgtatc tcagagaagg ctgggccgca tcaggatagg
     2641 taaaagtcaa ttcttggact tgtaaaacct tatctctggt agcttgcttt tgttctaact
     2701 ctgaatggat atcctctgga gcctcaacaa agacttcctc gattcgcttg actgagatat
     2761 aggactggtt gagggaattg atcaacatgg ctagcttgac caattccacc aaaatctgta
     2821 agaggtaatt gataagagca atgagagcac cttgactgag cactcctcct tgaattgaaa
     2881 tatagccttg ccagataata acgagaagag ttccattgac aatcagatag gtcagaggtg
     2941 ttaataaact agaccagaaa cctgtctttt cttgtaatct agcataaact tggttaaggg
     3001 tttgaaaaat ctgtaactct cgtttttctt gaccaaaagc acgaataacc cgcatccctt
     3061 gcaattgctg gcgcgtttcc tgaaccagtt ggtccgtttt ctttctgaga ctactgtaga
     3121 aaggattgac caatcgagat aaccctacaa tgacaatggt caaaatggca accaagacta
     3181 agaaccagaa agtcaactca gctgagattc gataagccat aaaaatggca ccaaaaacga
     3241 taatgggcgc tcgtaaaaag agacgcagga attgattgat accagtctga atctggtagg
     3301 tatccgaagt caagcgagta accaaactag aagttgtcag acggtctctg ctgtcctttg
     3361 gcaaggaaag aatatgacga taaagatcgt ttgtcaattc cttagcaaaa cctactgctg
     3421 cctttgctga gtaaaattga gctatcaagg ccactaaaac gccaattact gcaaagataa
     3481 ggagcaggcc aatctgcatc cagagatgac cttgatctcc ctgaggtaaa gattggtcaa
     3541 caatcccagc aatcaccatg ggaaccaaga gctcaaaaac agcttctaac agcttgaaca
     3601 agggggctaa aattgattcc ttgatgtagg gtttgaagta agataatagg tgtttcataa
     3661 atcccttcta ttcatattct agaaatgaag aaagtgggaa gccccactct ctgttttatt
     3721 tgtttaagta aggcaataga tagccatatc ctgctttttc catctcatcc ttggccacaa
     3781 agcgtaaaga agcagaattg atacagtaac ggaggccgcc taactcccgc ggtccatctg
     3841 tgaaaacatg acccaagtga gcactgcctg aacgagaacg aacttcaatt cgctccattc
     3901 catggctcag atccttgtaa taatgaatca actctttgga aatcggacgg ctaaaacttg
     3961 gccaaccaca acctgaagca aacttatcct tggcaaaaaa gagtggctca cctgtcgtaa
     4021 tatctacata aatcccctct tcaaaggttt ggtcataggc attggtaaat ggagcctctg
     4081 tagcagcttc ttgtgtgaca cgataagact cttcagatag actggccttc aacacctctt
     4141 gactaggctt ttcatagttt gctgcatcaa tcaatggctt atcagcatcg gtcacatcga
     4201 tatgacagta acctgaagga ttcttcctga gatagtcttg gtggtagtct tcagccagaa
     4261 tgtagtggcg taattgctcc acttctactg caatctttcg acccagcatg cgttcctgct
     4321 cctgcaccac tgtgtagata gctggcaaat ctgcttcatc ctgataataa atcccagttc
     4381 gatattggcg gccacggtca ttcccttgtt gattgataga tagaggatcg ataactcgga
     4441 aataataaag taaaatctct ctgagtgaca cttccttctc atcgtaaatc acttggaccg
     4501 tttctgcatg gtctgtttcc ttgatcaact ggtaattggt cgtttcgact tgaccattag
     4561 cgtagccaac actggtttct agcactccag aaatgcgtga aaaatattcc tctaggcccc
     4621 aaaaacaacc acctgctaga taaatttctg ccatctttat ttctccttta tcacgttttt
     4681 aactaatact cttcgaaaat ctcttcaaac cacgttagcg tcaccttacc gtatatatgt
     4741 tactgac
//
LOCUS       DAVAGB010000085         4615 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVAGB010000085 DAVAGB010000000
VERSION     DAVAGB010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4615
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.087"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(112..549)
                     /locus_tag="VQO19_002047"
     CDS             complement(112..549)
                     /locus_tag="VQO19_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HET1350250.1"
                     /translation="MSQEFINPSDGVIRRYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLLDVARDFLKADA
                     KIFWAQLGLESLEAEEILRAGGCDDIVMNRCIKREHTRLIGEA"
     gene            complement(634..3267)
                     /gene="polA"
                     /locus_tag="VQO19_002048"
     CDS             complement(634..3267)
                     /gene="polA"
                     /locus_tag="VQO19_002048"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HET1350251.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAKGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCEDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKSYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3523..3873
                     /locus_tag="VQO19_002049"
     CDS             3523..3873
                     /locus_tag="VQO19_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET1350252.1"
                     /translation="MLRHPCISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWTYLCSQVN
                     QNLEKIRQREGDTH"
     gene            4088..4204
                     /locus_tag="VQO19_002050"
     CDS             4088..4204
                     /locus_tag="VQO19_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET1350253.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            4197..4430
                     /locus_tag="VQO19_002051"
     CDS             4197..4430
                     /locus_tag="VQO19_002051"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350254.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGREERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
BASE COUNT         1405 a         1106 c          853 g         1251 t
ORIGIN      
        1 gtatctacaa cctcaaaaca gtgttttgag caacccgcag ctagtttcct agtttgctct
       61 ttgattttca ttgagtataa cacaaaaggt agcccatcag ctaccttttt cttatgcttc
      121 cccaatcaag cgtgtatgtt ctctcttgat gcaacgattc atcacgatgt catcgcatcc
      181 accagcacgc aagatttctt ccgcctctag actttcaagt cccagctgcg cccaaaaaat
      241 cttggcatca gccttgagaa aatcacgcgc cacatcgagc agaaattcac tgcgacgata
      301 aacattgaca atatctacag gaaaaggaat ttcagcgagg ctagcataag ccttttcacc
      361 caagatttcg ccacctgccg ccttgggatt gactgggatg attttatagc cccgagcctg
      421 catttccttt gtcactcgat tgctggttgt ttcttcacgg tcagacaaac ccaccacagc
      481 aagggtttta ctcgttgcga gataccgacg aatcacgcca tcacttggat tgataaattc
      541 ttgactcata gaaatcctcc tttttcatca gtatagcata ttttgaaaag gtttgcagaa
      601 ttctactaca aaaaaggagg actagccccc tttttattta gcctcgtacc aggttgcccc
      661 ttcattctca tctgcgataa gaggaacact gagttgaatg gcttcttcca tggtttgttt
      721 caccaatttt ttcatctcta ccaattcaga tttaggcact tcaaggacga tttcatcgtg
      781 cacttgtaac agcatcttag tctgataacc acctgcaacc aaggctttat ccagctgaat
      841 catggcaatc ttgagaatat ctgctgccga accctggata ggtgagttga tagcagttcg
      901 ctccgcaaaa ccacgaatat tgaagttgcg cgaattgata tctggcaact cacggcgacg
      961 cttaaagagg gtctctacat agctcttatc acgcgcctcc cgcaccactt catccatgta
     1021 gtttttaata cctggaaaac gttcaaagta ggtatcaatg taggctttgg cttccttacg
     1081 actaattccc aaattattag acaagccaaa gtctgaaatc ccataaacca ctccaaagtt
     1141 aactgccttg gcattgcgac ggtcgtttgc agtcacatca tcaggacgct caatgccaaa
     1201 gacccgcatg gctgtcgaag tatggatatc tgccccctct tggaaggcct taatcaagtg
     1261 ctcatcctta gaaatatgcg ccaaaacgcg caattcaatc tgtgaatagt cagagctgag
     1321 tagcacacta tcctcccact ctggcacaaa agccttccga atcaagcgcc cctgttccaa
     1381 tcgggcagga atattttgca agtttggatc cacactagac aaacgcccgg tctgggtcaa
     1441 atcctgcaca tagcgagtat gaatctttcc atcagccaaa atccagtcct gcaagccaat
     1501 tacataagta gattgaatct tagcaatttg acggtaatcc aggattttct taacaatcgg
     1561 agcaatagga gcgagacgct ccaacacatc cactgctgtc gaataacctg tcttggtttt
     1621 cttagtgtat tctagaggaa gtcccaattt ctcaaagaga agcacgccca actgcttagg
     1681 cgagttgaca ttaaactcct caccagccag ctcgtaaatc tcttgagtca gtttttcaat
     1741 gacaagctca ttttcagcct gcatctcaag caaggtctct ttcttgacca taatcccagc
     1801 aatttccatc ttggcaagga caaaagccag aggttgctcc atatcataaa gaagctctaa
     1861 ttgcccattt tcgctgagtt tttcaagtaa aataggctct gtttctacca aaacagcaag
     1921 tttacaagct aagtgttcca agaatttctc acgttcagga atggcctttt taacaccctt
     1981 accgtagaaa gtttcatcat caaccaagta agtctgacca taaagactag cgatggtcgc
     2041 aatttcattg tcctccacag tcgaaaggag gtatttagcc aaacggatgt caaaagcagg
     2101 cgcctgcaaa tccacaccaa aacgttgcaa aagaacttta accttcttaa agtcataaac
     2161 tctcagagat gttttttcta agaaatcctt gaaaatcggg tcttgcaaca gctcaagctt
     2221 gtctgtggca tagagcttat cctcacaaga ccaggcaaat ccaaccaaat tatccgtatg
     2281 gtaattctca ccaaaaagct caaagtggaa gatagactct tcactcagca tatcttgact
     2341 gatttggtca acaatagtaa aatctaaacc cttagccaca tcagctgacg acacatttaa
     2401 agcctgcttg agctgtttga agcccatctc atcgtaaaat ttcccaagat tttcaacatc
     2461 tggaccacta tagaccaagt cctctaaacc aatcgcaatc ggtgccttgg tatcaatggt
     2521 cgctagtgtt ttagacaaaa aggcctgttc cttgtcattg atgagatttt ccttcatctt
     2581 agaagtcttc attccatcaa tattttcata aatcccctca agcgaaccat gctccagcaa
     2641 gagcttaata cccgtctttt caccgacttt ggtcacccca gggatattat ccgacttatc
     2701 acccatgagc gccttgagat cgataaactg agctggtgtg aggcccattt cttccatgag
     2761 gtaatctggc gtaaaggcct caaactcagc cacacctttc ttggaaattt caaccaccgt
     2821 atgctcatcc gtcagctgaa tcaaatcctt gtccccactg acaatggtaa tatcaaaacc
     2881 atcctgctct gctagcttat ccagcgtccc aatgatgtca tccgcctcat actgagccag
     2941 ctcatagtga cgaatcccca tatgatccag caactcacga atgaaaggaa attgctcacg
     3001 aaactcatca ggagtcttgg cccgaccacc cttatagtcc gcatacatct ctgtccggaa
     3061 ggtcgtcttt cccgcatcaa aagccaccaa aatatgactc ggctcaaccc gctccaacaa
     3121 atgactcaac atcaactgga aaccataaat cgcattggta tgcaaaccag ccgcattctt
     3181 aaaacggtcc aactgctgat acagcgcaaa aaacgcccga aaagctacag aagacccatc
     3241 aatcaataat aattttttct tatccataca cccattataa aggaaagaat caaaaaatac
     3301 cattgggaag agctagagca agtatttttc aaactttttc cgaataaata gatagagcca
     3361 gagaatctag taaacctaga tttaaaaatg tgctataata tagcatattg aatctataat
     3421 agtacatctt gactgctaaa atatttctat aaattaattt gacttttctg atagagttgt
     3481 tcacatctta tttcaactca ctatagaagg aggaaaagga ggattctcag acatccgtgc
     3541 atcagcccaa ctaatgattt gattgctaag aaaatattca gcaatccaga aatcacttgt
     3601 caatttattc gcgatatgct ggacttgcca gcaaaaaatg tgaccatttt ggagggaagc
     3661 gatattcacg tattactctc catgccttac tcggtgcagg atttttatac cagtatagac
     3721 gtcttggcgg agttggataa cggtactcaa gtaattattg agattcaagt ccatcatcag
     3781 aattttttca tcaatcactt gtggacttac ctgtgcagtc aggttaatca aaatcttgaa
     3841 aaaattcgtc agcgagaagg tgatactcac tagagctaca aacacatcgc tcctgtttac
     3901 gccattgcta tcgtggatag taattatttc tcagatgacc tggcttttca tagctttagt
     3961 atgcgcgaag acacaacagg tgaggtattg gcgattacca acaatggaca ggaaaaccat
     4021 ctggttaaga tggcattctt ggaattaaaa aatacagaga aaccagcaaa gacaaggttc
     4081 gcaagccatg gttggagttt ttcggcaaca agccctttac ccagcaaccg caacgagcca
     4141 ttacccaagc aaatcaactg ctggactaca agagctggtc cgaggaggac aggaaaatgt
     4201 ttagtcaact acatatgcga gaagaacaag tcttgttagc acaggactat gccttggaaa
     4261 ctgctagggc tgaaggcctt gaacaaggac tagagcgtgg gaaagttgaa ggaagggaag
     4321 aaaggaaact ttttgccttc ctagacatag tacgccaagg tcttctgact tctgaggttg
     4381 ccagccagca attaggtatg tcagtatctg aatttgaggc actgttgtaa aatggctcta
     4441 taatatttgt agtgtgtaaa tcccctatgg atattatgga gcctattttg tgtagaaaaa
     4501 aagtcccata tgacctataa tgaaaagcga caaaacaact cattagaaag aatcatatgg
     4561 aacaattaca ttttatcaca aaattactag acattaaaga ccctaatgtc cagat
//
LOCUS       DAVAGB010000086         4472 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVAGB010000086 DAVAGB010000000
VERSION     DAVAGB010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4472
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.088"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            <1..326
                     /locus_tag="VQO19_002052"
     CDS             <1..326
                     /locus_tag="VQO19_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET1350255.1"
                     /translation="TNGELIAPMTYEETMTSDFFEVWFQKFFLPTLTTPSVIIMDNAR
                     FHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEALLS
                     CSCFN"
     gene            complement(319..486)
                     /locus_tag="VQO19_002053"
     CDS             complement(319..486)
                     /locus_tag="VQO19_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HET1350256.1"
                     /translation="MKKRILSAGLTFTSDLLLAACGQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(651..2258)
                     /locus_tag="VQO19_002054"
     CDS             complement(651..2258)
                     /locus_tag="VQO19_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HET1350257.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDFLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLAQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTAAKEVLEKQVLAPWDAFCVELL"
     gene            2411..3895
                     /locus_tag="VQO19_002055"
     CDS             2411..3895
                     /locus_tag="VQO19_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HET1350258.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            3990..4472
                     /locus_tag="VQO19_002056"
     CDS             3990..4472
                     /locus_tag="VQO19_002056"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HET1350259.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
BASE COUNT         1297 a         1009 c          857 g         1309 t
ORIGIN      
        1 taacaaatgg tgaattaatc gctccaatga cttacgaaga gacgatgacg agcgactttt
       61 ttgaagtatg gtttcagaag tttttcttac caacattaac cacaccatcg gttattatta
      121 tggataatgc aagattccat agaatgggta agttagaact cttgtgtgaa gagtttgggc
      181 ataaactttt acctcttcct ccctactcac ctgagtacaa tcctattgag aaaacatggg
      241 ctcatatcaa aaagcacctc aaaaaggtat taccaagttg caataccttt tatgaggctc
      301 ttttgtcctg ttcttgtttc aattgactat attatcagcg taatagtcta atagatagtt
      361 aaatgtagtt ggatttccac taaaggttga tgagtaagtt tttgtatctg aacctgattg
      421 gccgcaagca gctaaaagca aatcagatgt aaaagtcagg cctgcactaa ggatacgctt
      481 ctttatgttc gtcttctttc tccttaatag tgggaatttg taaagttaat tgaatttcga
      541 gaatgaaggt ttataaacct tggttataaa aaacaaagga tttctgcctt ttatacagtc
      601 ttcccttgtt tttatacgat tttaatttta aatttttctg caaaaaatat ttatagtaat
      661 tccacacaga aagcatccca tggagccaag acctgttttt caagtacttc tttagccgca
      721 gtgttttcaa tcaagacaga tttgactttt ccttctactg tcaagtcttg ctcttcattg
      781 gacaagttag ccacaactag gaagcgacgg tcgccatcct tacgtatata agcaaagacc
      841 ttatcagccg tatcaagcaa ttcaaagtca gctcgaatta gccagctatt ctccttgcga
      901 atttggacca gtttctgata ggtatagaaa atagaatctg gatttgccag cgcttcttgg
      961 acattgatca tctcgtaatt tggattaacc gccaaccaag gttgacctgt tgagaaacca
     1021 gcgtttttgc tctcgtccca ttgcataggg gtacgggcat tgtcacgtcc aataacacgg
     1081 atactgtcca tgatttcttc aatcggaaca cctttttcaa gagcctcacg cgcatagttg
     1141 agagattcaa tatcttctac ttgagccagt gtttcaaacg gatagttggt catcccaatc
     1201 tcctcacctt ggtagatata aggagttcct ctcatgagat gaagtaagat tgcaaaggct
     1261 ttggcagatt tttcgcggta ttcttggtca tttccccaga ttgagacaat acgagggagg
     1321 tcatggttgt tccagaagag ggaattccag ccgtcctcaa ctcctaactc tgtctgccat
     1381 ttgttgaaga tttcttttaa cttagcgata ttcagctctt tttgatagtg ccatttaggc
     1441 tgaccttcct gatactgaag accgatatgt tcaaactgga agaccataga caattcttgc
     1501 ccctttggat cagagtagag cttggcaatc tctggcgttg ctccccaagt ctcccctact
     1561 gtcaagaaat ccttatctcc aaaggtcgcc tgattcattt ccttgagata gggatggagc
     1621 ataggaccat tattgactac cttctcgtca ggaattttgc caatcatgtc aataacatcc
     1681 atacggaaac caccaatacc tttatcaatc cagaagttca tcatctcata aattttctgg
     1741 cgaagttttt cattttccca gttgagatcc ggctgtttct tgctgaaaaa gtggagatag
     1801 tattgacctg acttttcatc gtattcccaa gcagacccac taaagataga atctaggtca
     1861 ttgggttcat cgcgccagat atagtagtct cgctcagggc tattaggatt ttcacaggcc
     1921 tctacaaacc aggcatgctc atccgaggta tgattgacca ccaagtccat gatgatacgg
     1981 atatcacgct tcttagcttc tgcaatcagt tgatccatat cctccatggt tccaaaaatc
     2041 gttgcaatcg cttgataatc agcaatatcg tagccattat catccatagg gctgtcataa
     2101 acgggagaaa gccaaattgc tgtgattcct agcttggcta gatagtccaa cttactggta
     2161 attcctggca aatcgccaat tccatctcca ttactatcca taaaactctt tggatagact
     2221 tgatagacta cggcattatg ccaccatttt tcttgcatct gtttacctca ttattttcat
     2281 aatctatagt ctatgatagc actttttaaa attttgtgca agcgtttgct taatcttttt
     2341 aatttctttt ttagctccgt agtttcctaa cttccaattt tttattataa tagagtccag
     2401 aggtaaaaaa atgaaaaaac aagcttttag ttctgaacaa tatttgaatt tacaacgcga
     2461 ccatattttg gagcgcatta accaatttga cggcaagctc tacttagagt ttggcggtaa
     2521 aatgttagaa gatttccacg ctgctcgtgt ccttcctggt tatgaacctg acaacaaaat
     2581 caagctcttg caagaattga aagagcaggt tgaggttgtg attgccatta atgctagcaa
     2641 cattgaacat tccaaagcac gtggcgactt aggcatttct tatgaccaag aagttcttcg
     2701 tttgattgac aaattcaatg aattagggat ttttgttggt tccgttgtca ttacacaata
     2761 cgctggccaa cccgctgcag atgccttccg caaccaactt gagaaaaacg gaattgattc
     2821 ttatcttcat tatccaatca aaggatatcc gacggatatg gatcacatca tttccccaga
     2881 aggcatgggc aaaaacgact acatcaaaac cagtcgcaac ttgattgtcg taaccgctcc
     2941 tggacctggt tctggaaaat tggcaacgtg tatgtccaat atgtatcacg accaaatcaa
     3001 tggcatcaaa tctggctacg ctaaatttga aaccttccct gtttggaatc ttccccttca
     3061 tcatccagtt aacttggctt atgaagctgc cacagctgac cttgatgatg tcaacatgat
     3121 tgaccccttc catcttcaaa cctatggaga aaccactgtc aactacaacc gtgatatcga
     3181 aatcttccca gtgctcaagc gcatgttgga acgtattctc ggaaaatcac catacgcttc
     3241 accgacagat atgggtgtca acatggttgg tttcgctatt acagatgacg aggctgctgt
     3301 cgaagcttct aaacaagaaa tcatccgccg ttactatcaa acagttcttg acttcaaagc
     3361 tgaaaaagtt ggcgaagctg ccgtcaagaa aattgagttg ctcatgaacg acctcggtat
     3421 cacacctgca gaccgtaagg ttgctgtcgt tgcgcgccaa aaagcagaag aaactggtgg
     3481 accagcccta gcctttgaat tgccaaatgg ggaaatcgtc actggtaaga actcagaact
     3541 ctttgggcct acagccgctg ccttgatcaa cgccatcaaa aaatcagctg acatcgctaa
     3601 agaagtaaaa ttaatcgagc cggaagttgt taagccaatc caaggtctta aaatcgatca
     3661 tctcggtagc cgcaatccac gccttcattc aaatgaaatc ctgattgcac ttgctatcac
     3721 agctacagaa aatcctgatg ctgcccgcgc tatggaagaa ctcggcaacc tcaaaggaag
     3781 cgaagcccac tcaaccatca tcttgactga tgaagacaag aatgtccttc gtaaactggg
     3841 tatcaacgta acctttgacc catactacca atacgaccgc ttatatcgta agtaaagatt
     3901 tcaacctctc cagcctcgga gaggttttct ctctgtctca ggagcaacct ttatgatata
     3961 atgagagaag aaaactgaaa ggatttacca tgtcaaaaga agttattgtc gaaagttttg
     4021 aacttgacca caccattgtc aaagcaccct atgttcgctt gattggggaa gaaacaggac
     4081 caaaaggaga catcatctcc aattatgata ttcgcttggt gcaaccaaac gaagactcca
     4141 tccctaccgc cggccttcac actatcgagc acctcttagc caaactcatc cgtacccgca
     4201 ttgacggcat gattgactgt tcgccatttg gttgccgcac aggcttccac atgattatgt
     4261 ggggacgtca caccagtgct aaaattgcag ctgttatcaa ggattcgctc aaggaaatcg
     4321 ctgaaactac tacttgggaa gatgtcccag ggacaaccat cgaatcttgc ggaaactaca
     4381 aggaccacag cctcttctct gctaaagaat gggcaaaact catcttggaa caagggattt
     4441 cagatgatgc ctttgaacgt catgtgattt aa
//
LOCUS       DAVAGB010000087         4390 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVAGB010000087 DAVAGB010000000
VERSION     DAVAGB010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4390
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.089"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            188..430
                     /locus_tag="VQO19_002057"
                     /pseudo
     CDS             188..430
                     /locus_tag="VQO19_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800706.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            complement(788..1321)
                     /locus_tag="VQO19_002058"
     CDS             complement(788..1321)
                     /locus_tag="VQO19_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HET1350260.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(1410..2186)
                     /gene="recX"
                     /locus_tag="VQO19_002059"
     CDS             complement(1410..2186)
                     /gene="recX"
                     /locus_tag="VQO19_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HET1350261.1"
                     /translation="MKITKLEKKKRLYLMELDNVDKCYITEDTIVRFMLSRDKVISKE
                     ELTEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDENIVSQVIANLKEDKW
                     INDGQYAYTIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASVLREYL"
     gene            complement(2196..2972)
                     /locus_tag="VQO19_002060"
     CDS             complement(2196..2972)
                     /locus_tag="VQO19_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HET1350262.1"
                     /translation="MNSKTPRFSILDFPEQLRSYIKGANLSDSSSHSSATVLYIDSGY
                     YLKIDQKGRLAQEAKITSWFETEGLGTPVITYLSANKDFLLTKEAIGSNALAFLNQPE
                     KLCQTLAQALNKLHSLKPQSFPSENHLKRYKEKALKNYQKGTFYNKTLLPQFHIHSRE
                     EAYQLIQEKGYILKADAFIHGDACLPNFILKDASHFSCFIDLGLAGFSDRHIDLFWAI
                     WSLHYNLQDATYAELFLDYYGREYVNMDKLRLVAAFEAFR"
     gene            3029..4384
                     /gene="rlmD"
                     /locus_tag="VQO19_002061"
     CDS             3029..4384
                     /gene="rlmD"
                     /locus_tag="VQO19_002061"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET1350263.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT         1415 a          739 c          787 g         1449 t
ORIGIN      
        1 ctaaaatctg gatattaggg tctttaatgt ctagtaattt tgtgataaaa tgtaattgtt
       61 ccatatgaat ctttctaatg agttgttttg tcgcttttca ttatagatct tatgggactt
      121 tttttctaca caaaataggc tccataatat ctatagtgga tttacccact acaaatatta
      181 tagagccgaa aattcacatc taatatatgc agactacttt gaaatgaaat tacaaaaatt
      241 attaaaagat gacacaaaag tttttgaaaa atctacattc aaatttgtag aaggatataa
      301 aatatacctg acagaatcta aagaatctgg aattaaacaa atggacaatg tcataaaata
      361 ttttgagttt attgaatcta aaagtattgc tttatatttt caaaaacgat taaatgagct
      421 gatagattaa atagcatttt ctctgttgag atattgtttt taaaatattg tactaaatga
      481 ttgatgctat gtggaaatac aaaaaaatgt ttttgatacg aagttgacct gtatttttta
      541 tactaatcat tttcgtattt tttgtattaa acgatataag tttgttgtaa acttacaagg
      601 aataaagaca ttaaaaaata acagtatatc tatttgtttt atatatttta cgaattctgc
      661 ataaatttct ttctagtaat gtgttgtaac tctgctataa tggatttatt cctttttgtg
      721 tttacacaat ttattttata ctaccaaaaa aacaaggtca ggattttgtt cctgaccttt
      781 gacaacttta ccgattcttt agttctacat agcgcttgta ccaaatgttt acataggctt
      841 ctgagaaagg accacgtcca ttgttaatcc aatcaacaag aattttgaca tgttctttta
      901 aaatatagtc caagtcatca gaataattca ttttgcgttt gtgacgctcg tattcttcaa
      961 cgtccaagag acgtttttcc ccatctgtaa aaattttaac atccaaatcg taatcaatat
     1021 acttcagtgc ttcttcatcc agatagtagg ggctagccat attgcaatag taagaagttc
     1081 cattatcacg aatcatggca atgatattaa accaatattt cttgtgaaag taaacaatag
     1141 ccggttctcg agtgacccaa cgacgaccat cactttcggt aacaagtgta tgatcgttga
     1201 caccaataat ggcgttttct gttgttttta gtaccatggt gtcccgccaa gttcggtgga
     1261 gactcccatc atgcttataa ctttgaattg taataaagtc gccttctttt ggaagcttca
     1321 taactaacca actttctaca atttataagt ttatcattta ctattgtacc ataaaattac
     1381 ctaaaatctg tgaatttcac ttggaaatat taaagatatt ctctaagaac gcttgctata
     1441 tccgaaaaat cgtagccctt tcgtgctaaa acttgagtta aacgttgctt cagttcgtat
     1501 ccttcatact ttcgggcata cttagtatat tgcttatcaa gttccttgaa gatgagttcc
     1561 tgagtcgttt cttggtcaac ttggctatct aagtcgtcaa aggcaatttt agcatcagaa
     1621 taagagaagc ccttgttagt caagttctgg ataatcttat cttgcagggc acgagctgga
     1681 agttttccct catatttttt caatagttta ttagctacac gttgagcaac ttcagaaaaa
     1741 tcaaattctt tcaagttctc ttctatagta gattttgaaa tccctttttg agctagtttc
     1801 tgagtcagca cataaggacc cttgtctcct gaaagttgat tggtattgat gatagtataa
     1861 gcgtactgac catcattaat ccacttatct tctttaagat tagcaataac ttgagaaacg
     1921 atgttttcat caatatcgta ttttttcaga tattctctga cttctttttc agtgcgtgct
     1981 ttaaaggata agtggtagag ggccagattc ttaccataag aaaactgggc aaaatcctga
     2041 atctcggtca gttcctcttt actaatgacc ttatctctcg ataacataaa acgaacaatt
     2101 gtgtcttcgg tgatatagca tttgtcgaca ttatcaagct ccatcagata gagtcttttt
     2161 ttcttttcaa gttttgtgat tttcataatt tcctttcatc taaatgcttc gaaagctgca
     2221 acaagtcgga gtttatccat atttacatat tctctaccgt aatagtcgag aaataattca
     2281 gcatacgtag catcttgtag gttgtaatga agggaccaaa ttgcccaaaa gaggtcgata
     2341 tgtcggtcac taaaaccagc caatcccaag tcaataaagc aagaaaaatg agaggcatcc
     2401 ttcaagatga aatttggcag gcaggcatct ccatgaataa aagcatcagc tttgagaatg
     2461 taacctttct cttgtatcag ttggtaagct tcttcacgac tgtgaatgtg aaattgaggc
     2521 agaagagtct tgttataaaa agtccccttc tgatagtttt ttaaggcttt ttctttataa
     2581 cgcttcagat gattttccga cggaaaagat tgtggtttaa gactgtgaag tttgtttaat
     2641 gcttgagcca gggtttgaca gagtttttcg ggttgattta aaaaagcgag agcgttgctg
     2701 ccaatggctt ctttagtcag aaggaagtcc ttatttgctg ataaataggt aatcactgga
     2761 gttcccaatc cttcagtttc gaaccaactt gtaatcttag cttcttgagc taatctgcct
     2821 ttttgatcta tttttaaata gtaacctgaa tctatatata ggacagttgc acttgaatga
     2881 gaagaactat cagagagatt agctcccttg atatagcttc gtaattgttc agggaaatct
     2941 agtatactaa agcgaggtgt ttttgaattc atgcttttat tgtaacatat tcttaaatat
     3001 cttagaaact ccatggtata atagacatat gaatctgaaa gtgaaacaaa aaataccatt
     3061 aaaaatcaag cgcatgggaa ttaacggtga gggaatcggc ttttaccaaa aaacattagt
     3121 ctttgtacca ggagctctca aaggcgaaga tatctattgt cagattactt ctattagacg
     3181 caactttgtt gaagcaaaat tactgaaggt caacaagaag tctaaatttc gaattgtgcc
     3241 atcttgtact atttataatg aatgcggagg ctgccaaatc atgcacctgc attatgataa
     3301 gcagctggag ttcaagacgg acttacttca tcaagcgctg aaaaaatttg ctcctgcagg
     3361 atatgaaaat tatgaaattc gtccaactat tggaatgcag gaaccaaaat attacagagc
     3421 taagttacaa tttcagactc gaaaatttaa aaatcaggtc aaggcgggct tatatgcaca
     3481 aaactctcac tatttagtag agttgaaaga ctgcctggta caagataagg aaacccaagt
     3541 gattgctaat cgcttagcag aattacttac ttatcaccag attccaatca cggatgagag
     3601 aaaagttcta ggtgtccgta ctattatggt ccgacgcgcg agaaagaccg gacaggttca
     3661 gattattatt gttacaaacc gccagcttaa tttaactcaa ttggtaaaag agttggttaa
     3721 agatttccca gaagttgtga cagtagctgt taatacaaat acagctaaaa ccagtgagat
     3781 atatggtgaa aagacagaga ttatctgggg gcaagagagt attcaagaag gtgtactcaa
     3841 ttatgaattt tcactatccc ctcgagcttt ttatcaacta aatcctgagc aaacagaagt
     3901 cctctatagc gaagcagtaa aagcgctgga tgttgataaa gaagaccatt tgattgacgc
     3961 ttattgtgga gttggaacga ttggatttgc ctttgcaaag aaagtaaaaa cactcagagg
     4021 tatggatatt attccagaag ctattgaaga tgccaagcga aatgctaaaa gaatgggatt
     4081 tgacaatact cattatgaag ctggaacggc agaagagatt attcctcgtt ggtacaagga
     4141 aggctaccga gcagatgctt tgattgttga cccaccacgt acaggtctgg atgataagtt
     4201 attagatact attcttactt atgtaccaga aaaaatggtt tatatttctt gtaatgtttc
     4261 gaccttggct cgtgatttgg tacgcttagt agaagtctat gatcttcatt atatccagtc
     4321 ggtcgatatg ttcccacata cagctcgaac tgaagctgtt gtaaaattaa taaaaaaagt
     4381 ttaaaaaagg
//
LOCUS       DAVAGB010000088         4248 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVAGB010000088 DAVAGB010000000
VERSION     DAVAGB010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4248
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.090"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            782..1774
                     /locus_tag="VQO19_002062"
     CDS             782..1774
                     /locus_tag="VQO19_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET1350264.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1776..2594
                     /locus_tag="VQO19_002063"
     CDS             1776..2594
                     /locus_tag="VQO19_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HET1350265.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2596..3381
                     /locus_tag="VQO19_002064"
     CDS             2596..3381
                     /locus_tag="VQO19_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET1350266.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3420..3686
                     /locus_tag="VQO19_002065"
     CDS             3420..3686
                     /locus_tag="VQO19_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HET1350267.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTRFVSLSYSSEDCAEIDCLGVKKLIKVEKLGAN"
     gene            3635..3880
                     /locus_tag="VQO19_002066"
     CDS             3635..3880
                     /locus_tag="VQO19_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET1350268.1"
                     /translation="MSRRKKAYQGRKIGSQLIATLESEARKKVAYLQVKTVAEGSNKD
                     YDRTNDFYRGLGFKKLEIFLQLWNPQNPCQILIKKLE"
BASE COUNT         1186 a          728 c          908 g         1426 t
ORIGIN      
        1 aaaacattta tagaaattaa ttttactttc ccaatcgatt tgttctcatc ttatttcaat
       61 ccgctatata ttatggtatc gaatcttcat cagaatgata aaattaatca attgatatct
      121 gattacaaac agaatatgaa agctttttat atcactattg aaaaatttat acgagatgat
      181 gaaagcctta agtgttattt tataaaggtt atttcaagtc gttccaaggt aacaagtcta
      241 gatcagattg aagctgataa aacgatacaa agaaaatatt caagtgagct aaaaaaattt
      301 attggatttt ataatgagat tatttgtgag gaaaatagtt tcctacatgt acgaaagagg
      361 tggtcgagtt ggtttaggta gtcgatgcgt gagttgataa ttctcagggt atggacttct
      421 ttttcatgaa tgaggtaaaa gagcaggtat tgtttagaga caatcattct gagcatattt
      481 tctggataga gggagtatcc gattttatga tcaaagttaa taccgccctc tggtgagaag
      541 atgagtaggt tggtaattta aactattaaa cagaattttt gattaaaagt attattttat
      601 gagagaaatc ctaatttcac aatccatagg caaacgcttg catttcgttt tttattggac
      661 tataataggt tggtataaag ccttttgtag taataaaatg tagaaggtgt agaaagcaag
      721 gatttagaat atttgtagtt aaaaacacaa tgttgctatt ccttacgata gggagataga
      781 tatggcaatg atagaagtgg aacatcttca gaaaaatttt gtgaagactg ttaaggaacc
      841 gggcttgaag ggggctttgc gctcctttat tcatcctgaa aagcagacct ttgaagcggt
      901 caaggatttg acctttgagg ttccaaaagg gcagatttta ggatttatcg gggcaaatgg
      961 tgctgggaag tcgacaacca ttaaaatgct gacaggaatt ttgaaaccaa catctggttt
     1021 ttgtcggatt aacggcaaga ttccccagga caatcggcaa gattatgtca aagatattgg
     1081 cgtagtcttt ggacaacgca cccagctatg gtgggatttg gctctgcaag agacctacac
     1141 tgtcttaaaa gagatttatg atgtgccaaa ctcgctcttt cataagcgca tggacttttt
     1201 gaatgaagtc ttggatttga aggactttat caaggatccc gtgcggactc tttcactggg
     1261 acaacggatg cgggcggata ttgcggcctc cttgctccac aatcccaagg ttcttttttt
     1321 agatgagccg accattggtt tggacgtttc ggttaaggat aatattcgtc gggcaattac
     1381 tcagatcaat caagaggaag aaactaccat tcttttgacc actcacgatt tgagtgatat
     1441 tgagcaactt tgtgatcgga ttttcatgat tgacaagggg caagagattt ttgatggaac
     1501 ggtgagccaa ctcaaggaga cctttggtaa gatgaagact ctctcttttg aactgctacc
     1561 aggtcaaagt catctcgtct ctcactatga aggtctgtct gatatgacca ttgatagaca
     1621 aggaaacagc ctcaatattg aatttgatag ttctcgctac cagtcagctg acattatcaa
     1681 gcaaaccctg tctgattttg aaatccgcga tttgaagatg gtggatacgg atattgagga
     1741 tattatccgt cgcttctacc gaaaggagct ctaggatgat caaattgtgg agacgttata
     1801 aaccctttat caatgcaggg gttcaggagt tgattactta ccgagtcaac tttattctct
     1861 atcggattgg cgatgtcatg ggggcttttg tggcctttta tctctggaag gctgtctttg
     1921 attcttcgca agagtctttg attcagggct tcagtatggc ggatatcacc ctctacatca
     1981 tcatgagttt tgtgaccaat cttctgacta gatccgattc gtcctttatg attggggagg
     2041 aggtcaagga tggctccatt atcatgcgtt tgttgcgacc agtgcatttt gcggcctcct
     2101 atcttttcac cgagcttggt tccaagtggt tgatttttat cagcgttggc cttccatttt
     2161 taagtgtcat tgtcttgatg aaaatcatat cgggtcaagg tattgtagag gtgctaggat
     2221 taactgtcct ttatcttttt agcttaacgc tcgcctatct gattaacttt ttctttaata
     2281 tttgctttgg attttcagcc tttgtgttta aaaatctttg gggttccaac ctacttaaga
     2341 cttccatagt ggcttttatg tcggggagtt tgattccctt ggcattcttt ccaaaggttg
     2401 tttcagatat tctttccttt ttgccttttt catccttgat ttatactcca gttatgatca
     2461 ttgttggaaa atacgatgcc agtcagattc ttcaggcact ccttttgcag ttcttctggc
     2521 tcttagtgat ggtgggattg tctcagttga tttggaaacg ggtccagtcc tttatcacca
     2581 ttcaaggagg ttagtatgaa aaaatatcaa cgaatgcatc tgatttttat cagacaatac
     2641 atcaaacaaa tcatggaata taaggtggat tttgtggttg gtgtcttggg agtctttctg
     2701 gctcaaggct tgaatctctt gtttctcaat gtcatctttc aacatattcc attcctagaa
     2761 ggttggacct ttcaagagat agctttcatt tatggatttt ccttgattcc caagggaatg
     2821 gaccatctct tttttgacaa tctctgggca ctagggcaac gcctagtccg aaaaggagag
     2881 tttgacaagt atctgactcg tcccatcaat cctctctttc acatcctagt tgaaaccttt
     2941 cagattgatg ccttgggtga actcttagtc ggtggtattt tattgggaac aacagtgacc
     3001 agcattgttt ggactcttcc gaaattcctg cttttcctag tttgtattcc ttttgcgacc
     3061 ttgatttata cttctcttaa aatcgcaaca gccagtatcg ccttttggac taagcagtca
     3121 ggcgccatga tttacatctt ctatatgttc aatgactttg ctaagtatcc gatttctatt
     3181 tacaattctc ttcttcgttg gttgattagc tttatcgtgc ctttcgcctt tacagcctac
     3241 tatccagcta gttatttctt acaggaaaag gatgtgttct ttaacgtagg aggtttgatg
     3301 ttgatttctc tggttttctt tgttatttcc cttaaacttt gggataaggg cttagattcc
     3361 tacgaaagtg cgggttcgta aaagctaaag taagactaaa atcaagaaag aaacttatga
     3421 tgtttgtaat tgaagaagtc aaggatgaaa atcaaaaaaa ggcagttgta gctgaggttt
     3481 tgaaggattt gccagaatgg tttggaatcc cagaaagcac acaagcctat atagaaggaa
     3541 ccacgacact gcaagtttgg accgcctatc aggagagtga tttgactaga tttgtaagct
     3601 tatcctattc gagtgaagat tgtgcagaga ttgattgtct cggcgtaaaa aagcttatca
     3661 aggtagaaaa attgggagcc aattgattgc tactttagag agtgaagctc gtaaaaaagt
     3721 tgcttatctg caggtcaaaa cagtggcaga aggttctaat aaagattatg atcgaacaaa
     3781 tgacttttat cgaggtcttg gctttaaaaa gttagagatt tttcttcaac tatggaatcc
     3841 gcaaaatcct tgtcagattt tgattaaaaa gcttgaataa tattacttga catctattct
     3901 cagagtgcca tactgtaagt gtaatcgccg atttagctca gttggtagag caaggcactc
     3961 gtaaagccta ggttataggt agataaacga ctgaggagtt gaaaaaatag ataggtagaa
     4021 gataaccgtt aagccttatt cttagcggtt atttatattg tttaatagcg ctgatatttc
     4081 atcaattatg cctgttttcg tgtttctggt agttgttcaa gtttattgct actatttttg
     4141 atggtatgaa tgtgcttata atgtatcccg gttaacgaaa gttttggact tatactcttc
     4201 gaaaatctct tcaaaccacg tcaacgtcgc cttgccgtgc gtatggtt
//
LOCUS       DAVAGB010000089         4100 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVAGB010000089 DAVAGB010000000
VERSION     DAVAGB010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4100
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.091"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            157..1323
                     /locus_tag="VQO19_002067"
     CDS             157..1323
                     /locus_tag="VQO19_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HET1350269.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKYDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            1439..2476
                     /locus_tag="VQO19_002068"
     CDS             1439..2476
                     /locus_tag="VQO19_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HET1350270.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPVGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            2674..3528
                     /locus_tag="VQO19_002069"
     CDS             2674..3528
                     /locus_tag="VQO19_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET1350271.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGEKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSKLEITDSDGI
                     VTRIRLAR"
     gene            3678..3918
                     /locus_tag="VQO19_002070"
                     /pseudo
     CDS             3678..3918
                     /locus_tag="VQO19_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
BASE COUNT         1222 a          746 c          939 g         1193 t
ORIGIN      
        1 cagtgctttg agcagcctgc ggctagtttc ctattttagt tggaactcga ttcaattcat
       61 gtgacaacgt gaaaatcgtt agagcatttt atatagaata tacatgggaa tggagcttac
      121 tcccattcct atatttaata gaaaaagagg aactcaatgc tacattatac aaaagaagac
      181 ttgctcgaat tgggtgcaga aatcactacg cgtgaaatct accaacagcc tgatgtatgg
      241 agagaagctt ttgaatttta tcaagcaaaa cgtgaagaaa ttgcagcctt tctacaagaa
      301 atcgctgata aatatgacta tattaaagtt atcttgacag gtgctgggac ttctgcttat
      361 gtgggagata ccttgctacc ttattttaag gaagtctatg acgaacgcaa atggaatttc
      421 aatgctattg cgacaacaga tatcgttgcc aatccagcaa cctatttgaa aaaagatgtg
      481 gcaactgtcc ttgtgtcttt tgctcgtagt gggaactcgc ctgaaagtgt ggcgactgtt
      541 gatttggcca aatccttggt ggatgagctt tatcaagtga cgattacttg tgcagcagat
      601 ggtaaattgg ctcttcaagc tcacggtgat gaccgtaatc tcttgctctt gcaaccagct
      661 gtctctaatg atgctggatt tgccatgact tctagcttta cgtctatgat gttgacagct
      721 ctcttggtct ttgatcctac agaatttgct gttaagtctg aacgttttga agttgtatct
      781 agtcttgccc gtaaagtttt agacaaggca gaagatgtca aagagctcgt tgatttagac
      841 tttaaccgtg tcatctatct aggcgctggt cctttctttg gacttgctca tgaagctcag
      901 ctcaagattt tggaattaac tgctggtcaa gttgcgacca tgtatgaaag cccagttggc
      961 ttccgtcacg gtccaaaatc tcttatcaac gacaatacag ttgttttggt ctttggtaca
     1021 acgacagact acactcgtaa gtacgacttg gacttggttc gtgaagttgc tggtgaccag
     1081 attgctcgtc gtgttgtgct tttgagtgat caagcttttg gtcttgaaaa tgtcaaagaa
     1141 gtggcccttg gttgtggcgg tgtcttgaat gatatttacc gtgtcttccc ttacatcgtt
     1201 tatgcccaac tctttgctct attgacttca ctcaaggtag aaaataaacc agatacaccg
     1261 tctcctacag gtacagtaaa ccgtgtagta caaggtgtca taattcacga atatcaaaag
     1321 taagacagtg tttatgaatt cttgacaaga ggatttgtaa attatcagat aaaccataga
     1381 ttgtcagtac gctttctatg gtttgtttgc ttgagagaaa tagtaaaagg agaacagaat
     1441 gaaagcatac acagagcgtg tatttggaaa tgttgagggc gaggatgtct tggcctatcg
     1501 atttgagaca gacggtggct accaacttga ggttatgact tatggcgcga ccatcttgcg
     1561 ctatgtcgca cctgacaagg ctggaaattt tgccaatgtt atcttgggat ttgatgactt
     1621 tgatagttat gtaggcaata gtcccaagca tggagcaagt gtaggtcctg tagcgggtcg
     1681 tattgcaggt gcgacctttg agctcaatgg taagacctat gaccttgagg ttaataatgc
     1741 tagcaactgt aatcacagtg gttcaactgg ttgggattcc agcttgtttg aagttgaaga
     1801 agtaagcgat catggcttga ctctctacac agagcgtaca gatgggacag gagggttccc
     1861 tggaaatctc aagatttgga tcagttatca cttggaagaa actggtgcct atgaaatcag
     1921 ctacaaggta acgaccgatc aggatacgct ggtcaatcca accaaccaca gctatttcaa
     1981 cttgtctggt gatttcacgc agacgattga ccgtcatgtc ttccaactaa acacagaggg
     2041 catttactca atcgctcctg acggtgttcc tgccaaaact ccagaagcca accgtgatgt
     2101 ggtcaaacac atctacaatg gtaccttgtt gaaggatatc tttgcagaag aagatgagca
     2161 aatccagctg gcatcaggtt tggatcaccc atttgccctt cctgtaggcc atgacaatgc
     2221 tggattcctt tatgaccaaa attcaggtcg cttcctgctt ttcaagacag aagctccttg
     2281 ctttgtggtc tacacagcaa actttgtgga tgaaagtgtc attataggag gtcagccaat
     2341 gctacagcac aatgggattg ctcttgaagc gcaagcttta ccagatgcca ttcacagtga
     2401 ccttaaaggc caagtcattc ttaaagctgg tcaaaccttc accagtaaga cacgttatga
     2461 acttgttgtg aaataaaaaa gctggtcaaa aagtctttaa aattaaaata acgcatattg
     2521 tcaggtgatg aaaagtttga taatatgcgt tttattatga aatgatttac tttatattat
     2581 cctgaaatgg tgttattttt gagttatctg gcttgacttt cttgatggaa attatataat
     2641 aattataatt acaacgagaa aagaggacca tttatgacct atgaatataa gagtcacatt
     2701 tatttggcag agacagtttt aaatgtaaag gatttggcca gtcaaacagc cttttatcag
     2761 caagttattg gtttagaaat cttatctcaa actgagacag agtccattct aggccttggt
     2821 gaaaaagtct tggtacagct gattcaagca caagagagcg gagaagtgag ggaacattat
     2881 ggtctttacc atttggccat tctcttgccc acacgcaagg ctttggctga tgtcttgaaa
     2941 cacctgacag atttacagat tcctcttgtc ggcggtgcag accatggtta cagtgaagct
     3001 atttacttgg aagatttgga gggaaatggc attgaactct atcgagataa gccagtttcc
     3061 acatgggata ttcgagaaga tggacgcatt atcggagtga cggaggctct tgcggcgcag
     3121 gacatttatg agttggggga aagagtagag ccctttatcc tggcagaagg tacgagaatg
     3181 gggcatattc atctttccgt caaggatagt cgaaagtcca gccagtttta tcaaaaggtg
     3241 ttagggctag aggataaatt cagtgtgcct agcgctagtt ggattgcggc tggagattac
     3301 catcatcatt tagcagttaa cgaatgggga ggaaaaggtc tggcttcgcg taagcaaggc
     3361 ttaccaggtt tagcctacta tgtcatcgaa gtcgcacata aaaaagaact gttaacgatt
     3421 gcccaacgag cacaagaagt tgacgcacca atcaaatgga tgacatcgag caaattggaa
     3481 atcacagact cagatggcat cgtgacccgt attcgtttag caaggtaaaa ttaggaattt
     3541 ttaataagtt ataagtattg ctagtttgct ttttgaacgg tctttggtaa cagaactgcg
     3601 tgagctggat gggtgagaat tttgacaaag aagctgatta gagatataat gaagaaaaat
     3661 cgagcaagga aaaagaaatg acaaattcaa agtatattac tcgtttgaaa cgttcagagg
     3721 gccagttgcg tgggattcaa aagatgattg aaggagatcg tgacgcaact gacagcagtg
     3781 agatctagtg tagagcgcgt gattgagatg ataattaccg aaaatcttac tgaatgtatc
     3841 aatcagccac tagatgattc tgaagctcaa aaggaacgct tagaaaaggc tatccgatac
     3901 ttgattaaac ggaaataaat gaatgttttg agacgatatg tgcaaaggtc tattaactat
     3961 tagaatagtt taatgtgagt caaaagaagt tgtaaaaaat ctttaaaatt aaaaaaacgc
     4021 atagtatcag gtgttttatt atgtagagac ttatactctt cgaaaatctc ttcaaaccac
     4081 atcagcttca ccttgccgta
//
LOCUS       DAVAGB010000090         2941 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVAGB010000090 DAVAGB010000000
VERSION     DAVAGB010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2941
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.092"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(85..1026)
                     /locus_tag="VQO19_002071"
     CDS             complement(85..1026)
                     /locus_tag="VQO19_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET1350272.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(1004..2767)
                     /gene="aspS"
                     /locus_tag="VQO19_002072"
     CDS             complement(1004..2767)
                     /gene="aspS"
                     /locus_tag="VQO19_002072"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HET1350273.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRVKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
BASE COUNT          858 a          693 c          590 g          800 t
ORIGIN      
        1 agatagaact gacgaagtca gtaacatata tacggtaagg cgacgctgac gtggtttgaa
       61 gagattttcg aagactatta atcactaatt atctatctca acaaatcttc ctagaatatg
      121 aacattttcc gagacagaga caaaggagct tggatccact tgtgtcataa tctgtttaaa
      181 ttcattaaac tctgcacgtg taatgacagt gattaaaact gcctttctct cgtgattata
      241 ggttccttct gcatcgtgga tcatggttgc tccgcggtgc aattttttat ggattttttc
      301 aattaccttc tctggatgat ttgtcacaat catggcctgc atacgctttt gcttagtaaa
      361 gactgcgtct gtcacacggc tagagacaaa gatggtaatc atagaataaa gagcgtattt
      421 ccaaccaaag gtcaaacctg ctatcagcat gatagttcca tttaccaaga aagaaatact
      481 accgacattc ttacccgttt tcttacgaat agtcaggcta acgatatccg tcccaccact
      541 ggagatattg tttcgaagag caaaaccaat ccccaaaccc ataacaacac ccccaaaaag
      601 ggaattgata atgggatcct ccgtcaaggt tgccacaggg acaaactgga taaagaagga
      661 actcatagat accgtgataa aggtaaagac ggtgaactta tggccaatct gataccaagc
      721 taagaccatc aaagggaagt taatggcgta gaagcttagc gaaatcggaa tatgaaaacc
      781 aaaccagtga ttactcaagg cagagataat ctgtgccaga cctgttgcac cactcgaata
      841 cacatgccct ggttggaaaa agaaattaac tgctactgct gataaaaaac catagaccag
      901 agaggccgaa atcttctcat catacttttc tcgagagata ctttgtaaga cacgtaaaat
      961 ttttatctga taagcaaagc ggcgcagata atagcgccac cgcttaattc gttttgtttg
     1021 tttcatcttc ttctacttgt aagctgagtt cctctagttg tttgagagcg actgttgatg
     1081 gagcttgtgt cattgggtca gttgccttgt tgttcttagg aaaggcaatg acttcacgga
     1141 tattttcttc tccagcaagc aacatgacaa aacggtcaag cccgatagcc aaaccaccgt
     1201 gtggtgggaa accatagtcc atggcttcaa gaaggaaacc aaactggtca ttggcttctt
     1261 cagctgagaa accaagagcc ttgaacatgc gttcttgaag gtctttttgg ttgatacgaa
     1321 ggctaccacc accaagctca taaccgttca agacgatatc gtaagcaatg gcacgaacct
     1381 tagccaaatc accttctaat tcgtgagcag tctcttcctg tggaagggtg aaaggatggt
     1441 gggcgctcat gtagcggcct tcttcttcag accattcaaa catcggccag tcaaccaccc
     1501 aaaggaagtt gaacttatca ttatcaatca agccaagctc tttagcaata cgtccacgaa
     1561 gggcacccag tgttgcatta gccacttcaa gcgtatccgc cacaaagaga accaagtcct
     1621 tatcttcaag agcaagcgct gttgtcaatt cttcttggat accagtcaag aacttggcaa
     1681 ctggtccgtt taattctcca tcaaccacct taacccaagc aagacctttg gcaccatact
     1741 gtttggctac ttccgtcatc ttgtcgatgt ctttacgtga atagttgtcc gcagctcctt
     1801 tgaccacaat cgcttttaca gcaggtgctt ctgaaaagac tttaaagtct acacctttga
     1861 ccacttctgt caagtcctga agcaacatgt caaaacgagt atctggcttg tcagaaccgt
     1921 aaagagccat agcatcatcg tatttcacac gagggaacgg tagcgttact tcgatgcctt
     1981 ttgtttcctt catcacgcgc gcgatcaagc cttctgtaat atcttggatt tcttgctcag
     2041 taaggaagga cgtttccaag tcgacctgag taaattcagg ctggcggtct ccacgcaagt
     2101 cttcgtcacg gaaacattta acgatttggt agtaacggtc aaaaccagca ttcatcaaga
     2161 gctgtttcgt gatttgtgga ctttgaggaa gagcgtaaaa atgcccctta ttaacacgag
     2221 acggcactaa ataatcacgc gccccttcag gcgttgactt agaaaggaat ggtgtctcca
     2281 cgtcgataaa ctccaactca tccaagtagt tgcggataga gtgggtcacc ttggcacgaa
     2341 gtttaagatt ttccaacatt tctggacgac gaaggtcaag gtaacggtaa cgcaaacgtg
     2401 tatcgtcatt tgcctcaatg ccatccttaa tctcaaatgg tgttgtctta gctgtgttaa
     2461 gcacaataag agctgtcacg tttaactcaa ccgcaccagt tggcaactta tcattggctt
     2521 gctcacgcgc agcgacctga ccagtcacct caataacaaa ttcgctacga aggctttcag
     2581 ctgttgccat aacctctgca gatacttttt cagggttgat aaccaactgc atgattcctt
     2641 cacggtcacg aagatcgata aagatcaaac caccaaggtc acgacgacgg ccaacccatc
     2701 ctttcaaggt tatttcttgt ccgatgtgtt cctcacgaac acgaccagca tacatactac
     2761 gtttcattat ttctctcctc ttttattctg ttactatttt accataaaag cgcaggctct
     2821 tcatgaaaat catcagaaaa gtttgccagt ctttaaaagt caggtgaaag ccctaaaaat
     2881 tagcgctaat gctcttcgaa aatctcttca aaccacgtca gcgtcgcctt accgtaggta
     2941 t
//
LOCUS       DAVAGB010000091         2931 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVAGB010000091 DAVAGB010000000
VERSION     DAVAGB010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2931
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.093"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            107..271
                     /locus_tag="VQO19_002073"
     CDS             107..271
                     /locus_tag="VQO19_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET1350274.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPAIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            355..921
                     /gene="amaP"
                     /locus_tag="VQO19_002074"
     CDS             355..921
                     /gene="amaP"
                     /locus_tag="VQO19_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HET1350275.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            933..1103
                     /locus_tag="VQO19_002075"
     CDS             933..1103
                     /locus_tag="VQO19_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HET1350276.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1142..1750
                     /locus_tag="VQO19_002076"
     CDS             1142..1750
                     /locus_tag="VQO19_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET1350277.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1781..1984
                     /locus_tag="VQO19_002077"
     CDS             1781..1984
                     /locus_tag="VQO19_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET1350278.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2094..2372)
                     /locus_tag="VQO19_002078"
                     /pseudo
     CDS             complement(2094..2372)
                     /locus_tag="VQO19_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2570..2857
                     /locus_tag="VQO19_002079"
     CDS             2570..2857
                     /locus_tag="VQO19_002079"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET1350279.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCSRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
BASE COUNT         1006 a          450 c          569 g          906 t
ORIGIN      
        1 ttttttgata ttaaaataaa aaaggagggt aggcagtgtt gtgatcaatt attgctggag
       61 gtcttattgg tctcttggca ggtaaaatca ctaaaaaagt agttctatgg gaatcatcgc
      121 aaatgtattc gctggtttag tcggggcata tgcaggacaa tctcttttag gtagttgggg
      181 tccagcaatc gctggaatgg ctttgctccc atctattgta ggtgcagcga ttgtgattac
      241 tgtagtgtca ttctttacag gtagaaagta aacttttcgc cagtaaagtt agcaaactat
      301 ttttaaatca atgacgggaa aaatagttta aatgttaaat cgaaaggatt gtatatgtca
      361 aaagcaaaga aaatatgttt cattattttc tgtattttaa tcttgacaat tttccttcct
      421 gttttgatag attatcatca agttagtgat ctaggtattc atctacttag ctggagacag
      481 aactccgtag ttgaattcta tcttgctaga tatgtctttt gggggacagt ggttctatca
      541 actttagttt tattatccat tttagttgtg atgttttatc ctaaacgtta cttggaaatc
      601 caacttgaaa ctaaaaacga tacattaaaa ttaaagaatt cggcaatcga aggttttgtt
      661 agaagtttgg tgagtgatca tagattgatc aagaacccaa ctgttcatgt aaatttacga
      721 aaaaataaat gtttcgttca tgtagaaggt aaaattcttc cttcagacaa catcgctgac
      781 agatgccaaa taattcaaaa tgaaataact aatggattga agcagttttt tggtattgag
      841 cgtcaagtaa aacttgaagt tgcagtaaaa aattaccaac caaaacctca aaacaaaaag
      901 actgttagtc gtgtgaagta aggaagtaaa aaatggaatg gcttaaacaa tatcgatatc
      961 caattatcgc tggtctcata ggcgtatttc tggcttgttt gattgtctcc tttggcttct
     1021 tcaaaacaat atttgtattg attttaggag cactgggagt tgcagctgga ttatatatcg
     1081 aaaaaaacta tatagataaa taaaaaaata aaaattacta atttaattaa aggagtttca
     1141 tatgtcaaac gaaaaaaaca caaacactaa cgtagaaaag aaagatgcta ctgttgtagc
     1201 tcacgaaatc aaaggggaac ttacttacga agataaagtt atccaaaaaa tcattggtct
     1261 ttcactagaa aacgtttcag gtcttttggg aatcgatggt ggtttcttct caaatcttaa
     1321 agaaaaaatc gttaacagcg atgacgtaac aagtggtgtt aacgtagaag ttggtaaaac
     1381 acaagttgca gttgacttaa acgttattgt tgagtaccaa aaaaatgttc cagctttata
     1441 ttcagaaatc agagaaatcg tatcttcaga agttgctaaa atgactgact tggaaattgt
     1501 tgaaatcaac gtaaacgttg tcgacatcaa aactaaagaa cagcatgaag cagactcagt
     1561 aagccttcaa gatcgcgtat ctgacgttgc tgaatcaaca ggagaattca cttcagaaca
     1621 attcgaaaaa gctaaatctg gtcttggatc tggtttctca actgttcaag aaaaagttag
     1681 cgaaggtgta gaagctgtta aaggtgcagc aaatggtgta gtatctcacg aaaacactcg
     1741 tgtaaactaa gataaaataa atataacagg agaaattatc atgtcagtag aagaaaaatt
     1801 aaatcaagct aaaggttcta ttaaagaagg tgttgggaaa gccatcggtg atgaaaaaat
     1861 ggaaaaagaa ggtgcagctg aaaaagttgt ttctaaagta aaagaagttg ccgaagacgc
     1921 taaagacgct gtagaaggtg ctgtagaagg tgttaaaaac atgttgagtg gcgacgataa
     1981 ataaggttaa aagttgcttt atctttttag taatattagt caaaagagtc tgagtcaaga
     2041 tgattctcag aaaacaaaaa gctagagatt cccaattgcg gaactctagc tttttaattt
     2101 tgcctctttc tcttattata tttcagcagg ttgttggcca tgagtacgaa tcccatgtca
     2161 attctcactt gacgcttacc tctcagatga catctcttat aacccaaaca aacctttatc
     2221 tgcccaaaga cagatttcat atcaatctta cgtttagcga aaatttgtct acccttggaa
     2281 gataaaagtg cctgatattc tttagttttt aaacactggt aacgttcatt catatacagt
     2341 ctcttttgag gggctgattc aggttcataa tcgcagtcaa cattgatttc aaggctgttt
     2401 gctttctatc tccccttttt catgatatat tttcgtacag gttcttcaat agtttctata
     2461 gtaaaatgaa ccaaaaatag tacacgttgc ggtataatgt tcttgtggca tattcattag
     2521 attttcgtaa acagttctct cctatttgtg agcgaacagg tatagtcaat tgattgtcag
     2581 tttgaagacc aagagtcgta aggcaaagga tatggcagaa tccatccaag ggtggctggc
     2641 acaatttcta gtgaacctct ttaaatctat tacgtttgac tgtggaaaag agttttcaaa
     2701 atggaaagat atttccaatc atcacgatag tgagagcttt tttgcgaatc taggatgttc
     2761 aagacagcgg tgtctcaacg aacattcaaa tagactttta aggtgtcatg acttgccaaa
     2821 gcagacagat ttcaacgaag tcagtcaaga attttaggct ggacaaaaac tcaatttcag
     2881 gagaaaatga aataaatatt cccacaataa aacgcatagt atcaaagttt t
//
LOCUS       DAVAGB010000092         2807 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVAGB010000092 DAVAGB010000000
VERSION     DAVAGB010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2807
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.094"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(<1..161)
                     /locus_tag="VQO19_002080"
     CDS             complement(<1..161)
                     /locus_tag="VQO19_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET1350280.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFKEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDL"
     gene            200..1159
                     /locus_tag="VQO19_002081"
                     /pseudo
     CDS             200..1159
                     /locus_tag="VQO19_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821651.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            complement(1180..2124)
                     /gene="manA"
                     /locus_tag="VQO19_002082"
     CDS             complement(1180..2124)
                     /gene="manA"
                     /locus_tag="VQO19_002082"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HET1350281.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADDLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGSHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(2245..2541)
                     /locus_tag="VQO19_002083"
     CDS             complement(2245..2541)
                     /locus_tag="VQO19_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HET1350282.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYQDGVDLLGYTTWG
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGALKRSKKKSFYWYKDVIYSNGASIG"
     gene            2606..2728
                     /locus_tag="VQO19_002084"
                     /pseudo
     CDS             2606..2728
                     /locus_tag="VQO19_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          748 a          661 c          518 g          880 t
ORIGIN      
        1 aggtcttcta ggcttaattt aggttttcgt ccaccttttg cgtgtttaag ttgataagct
       61 gtttttaata cagctaacat ctctttaaaa gtcgtgcgct gaacaccaac aagacgctta
      121 aatcgtgcat cagttagttg tttacttgct tcatcattca tagaactact atgccatatt
      181 ttgtttcgca ggaagtctga tcatttcaaa tccagccatt gctctaggag ctcaagcgac
      241 ctttatccta ttgaatatct tcattgtatc acgtggggtt caaaaaggga ttgaaagagc
      301 ttcgaaagtc atgatgcccc tgctctttat catctttgtc gtcatcatcg aacgctctct
      361 cagtttgcca aatgccatgg aaggggttct ttacttcctc aaaccagact tttcaaaact
      421 gactagcact ggtctcctct atgctctggg acaatctttc tttgccctct cactaggggt
      481 tacagtcatg ttgacctatg cttcttactt agacaagaaa accaatctag tccagtcagg
      541 aatctccatc gtagccatga atatctcgat atccatcatg gcaggtctag ccattttcca
      601 agctcgatcc cccttcaata tccagtctga agggggaccc agcctgctct ttatcgtctt
      661 gcctcaactc tttgacaaga tgccttttgg aaccattttc tacgtcctct tcctcttgct
      721 cttccttttt gcgacagtca ctttttctgt cgtgatgctg gaaatcaatg tagacaatat
      781 caccaaccag gataacagca aacgtgccaa atggagtgtt attttaggaa ttttgacctt
      841 tgtctttggc attccttcag ccctatctta cggtgtcatg gcggatgttc acatttttgg
      901 taagaccttc tttgacgcta tggacttctt ggtttccaat ctcctcatgc catttggagc
      961 tctctacctt tcacttttta caggctatat ctttaaaaag gctcttgcaa tggaggaact
     1021 ccatctcgat gaaagagcat ggaaacaagg actgttccaa gtctggctct tccttcttcg
     1081 tttcttcgtt tcgtcattcc aatcatcatc attgtggtct tcattgccca atttatgtaa
     1141 tcaaaaagga cttgagtagt gaactcaggc cctttctttt tatggatggc taacaatcaa
     1201 ttccaaacct tgcccttcca gagtccaagc ttcaacatca cttggtagga taaagtggct
     1261 gcctttttga attggataat ttttcccgtc aacagttagc tgaccttgac cagccaagac
     1321 actcaataag ctgtagtcag ctgtcttttc aaagtcaact tttccagtaa tttcccactt
     1381 gtaaactgcg aagaaatcat tagatacaag gagagtggaa cgcaaatcat ctgctttaac
     1441 agttacagga cggctatttg ctggctcacc aatgttcaag acatcgatgg atttttcaag
     1501 atgaagttca cgcaagttgc ctttgtcatc cttgcggtca aagtcataga cgcgataggt
     1561 ggtatcgcta gactgctggg tttcaaggat taagataccc gccccgatag cgtgcatagt
     1621 cccgcttggt acatagaaga aatctccagc cttaacaggg actttggtca acaagtcatc
     1681 ccagttcttg tcctcgattt gctggcggag ttcttctttt gacttggcat tgtgaccgta
     1741 gataatctct gaaccttcat ccgctgcgat aatgtaccag cattctgttt ttccgagttc
     1801 gccttcatgc tcgagtccat aagcatcgtc tgggtgaact tggacactga gccagtcgtt
     1861 ggcatcgagg atcttggtca aaagtggaaa tacaggttct ggacgattgc caaataattc
     1921 acggtgttcc gcatacaaag tagcaagatc tgttccctcg taacgaccat tggcaacttt
     1981 agagactcca tttggatggg ctgagatggc ccaatattct ccgatttttt cacttgggat
     2041 gtcgtagcca aactcatcac gtagcttggc tccaccccag attttttctt gcataactga
     2101 ttgtaaaaat aatggttctg acatgtcgat ctcctgtctg atttttctcc cctcattata
     2161 gcaaaaaaag agttcgaatt gaactctttt ttacatctta taaagcaggg agaagatttt
     2221 ataaaaatag taaacaaatg tgctctaccc gatgcttgca ccattgctat aaatgacatc
     2281 cttgtaccaa tagaaggact tcttcttgct acgtttgaga gctccgtttc ctacattatc
     2341 tcgatctaca tagataaagc catagcgctt attcatttcc cctgtgccag ctgaaaccgg
     2401 atcgatacag ccccaagtcg tataaccaag caagtcaacc ccgtcttggt aaatggcatc
     2461 tcgcatggcc ttgatgtggg cctctaagta agtaatccga tagtcatctg ctacataacc
     2521 attctcatcc ggtgtatcca tagcaccgag tccattttct acgataatac taaactaaaa
     2581 tcaaaaagca ttatataata gtgatatgaa atcaactaaa gaagaaatcc aaaccatcaa
     2641 aacactttta aaagactctc gtacagctaa atatcataaa tgccttcaaa tcattctatt
     2701 tcgtctgatg ggcaaatctt ataaagattc cgactaatat tggttttacc tttattcctc
     2761 catacacacc agagatgaac ccatcgaaca agtgtggaaa gagattc
//
LOCUS       DAVAGB010000093         2689 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVAGB010000093 DAVAGB010000000
VERSION     DAVAGB010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2689
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.095"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(160..1665)
                     /gene="pyk"
                     /locus_tag="VQO19_002085"
     CDS             complement(160..1665)
                     /gene="pyk"
                     /locus_tag="VQO19_002085"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HET1350283.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(1724..>2689)
                     /gene="pfkA"
                     /locus_tag="VQO19_002086"
     CDS             complement(1724..>2689)
                     /gene="pfkA"
                     /locus_tag="VQO19_002086"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HET1350284.1"
                     /translation="GMNAAIRAVVRQAISEGMEVFGIYDGYAGMVAGEIHPLDAASVG
                     DIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGGDGSYHGAMRLTEHG
                     FPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSHRRTFVIEVMGRNAG
                     DIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNIIVLAEGVMSAAEFGQ
                     KLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLLKEGIGGVAVGIRNE
                     KMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSLS"
BASE COUNT          751 a          621 c          498 g          819 t
ORIGIN      
        1 aacatatata cggtaaggcg acgctgacgt ggtttgaatt tgattttcga agagtatcaa
       61 tccattatga aagttttgcc cccctttttg ccccctggac aaaaaaagag cccatcatac
      121 aggctagaaa gctggatatg ataggttttt atatttttct taacgtactg tgcggatacg
      181 cattgtgttt gtgcgaacag cttctcctac tggcacacca gcaacgataa cgatatcatc
      241 gcctgactca acgagacctg cttctaccgc tttacgttca gcgatttcga acatatcgtc
      301 agttgaagat ggagcatctg tcaacattgg gataacaccc cagttcaaca tcaagccacg
      361 ttctgtcaat tcgtcaaatg tcaatgctaa gatgtcagca tttggacggt atttagaaat
      421 caaacgtgca gtatgacctg tcttagtaag agttacaacc aatttgatat ccattgagct
      481 agtagcatct ttaacagcag aagccattac ttctgtctta gagttacgct caaatgaatc
      541 tgaatcaaga cgtccgtatt cattaagaag agcttgagcg ttcttgtcga ttgtagccat
      601 tgtagttact gactcgagtg ggtatttacc gtttgcagac tcgcctgaca gcattgtagc
      661 gtcagttccg tcgataacag cgttgaatac gtctgatact tctgaacgag ttgcacgtgg
      721 tttttcagtc attgtttcaa gcatgtttgt tgcagtgata acaactttac ctgcagcatt
      781 gactttcttg ataatcattt tttgataaac tggaaccatt tcgaacggta cttcgatacc
      841 catatcacca cgagcaatca taataccatc agctgcttcg ataatttcgt ctaagttatc
      901 gataccttgt tggttttcga ttttagcgaa caattgaaca tgtccgtttc cagtttcttc
      961 acagattgca cgaacttcgt tcacatcttt tgcagtacgt acgaatgaaa ttgcgatgaa
     1021 gttgatacct tgttcaagac cgaaacggat atcgtcgtta tcgcgttcag caagagctgg
     1081 gaaaggaatt ttagtgttag ggatgttcac acctttttgt ttagcgatga taccatcgtt
     1141 ttcaacttca acttcaaatt cacgagttgc atcatcttta gcaaccacac gaagaccaag
     1201 tttaccatcg tcaaccaaaa cttgacgacc aacttcaaca tcatcataga tatcaagagc
     1261 accagcaacg ttcaacgcaa tcacttcacg agttgatttg attccttgtt tagttgcaac
     1321 acgaattttt tcaccagttt tgtatgaata ttctttagct tcaccttcga acaattctgt
     1381 acggatttca ggtccttttg tatcaagaag gaaaccaact tttttacctg caattttttc
     1441 cgcaagttta acagttgcca tacgctcacc ttgttcttgg tggtcgccgt gtgagaagtt
     1501 gaatcggaat gtgttagcac cagcttcaat caatttagca atgtttttag ctgaagcttc
     1561 aacatcaagt ttttcacccc agtatccgtc ctcaccgaat tttttaccac cacggatttc
     1621 taccgcagga cccaaagttg caacgatttt tacacgtttg ttcatgattt ttgtgactcc
     1681 tttatatata tgaccttttt ggtcttatta actaaattgt aaattatgac aagctcttat
     1741 tcaagctaga tagctcaata tcggctttgt gtgggttgtt aaccacaatc ttaccttctg
     1801 cagtaaggct aaacaatgcc ccttcttctg cagtaccaag aattggattt tcaaccattt
     1861 tttcgttacg aataccaacc gcaacaccac cgataccttc tttaagaagt ttaacagcat
     1921 gtgcacccat acgtgacgcc aaaacacggt cacgcgcagt tggagaacca ccacgttgaa
     1981 tatgtccaag ttctgttaca cgaaggtcgc ttgtatctcc agcttcttta agtttttgac
     2041 caaattcagc cgctgacatc acaccttcag ctaagacgat gatattgtgt tttttaccac
     2101 attcataacc agctttgatg cttgctacga tatcttccat cttgaagcct gcttcaggga
     2161 tgatgatttc atcagcacca gttgcaatac cagcccaaag agcgatatca ccagcgttac
     2221 gtcccataac ttcgattaca aaagtacgac ggtgacttga tgatgtatca cgaatcttat
     2281 cgatagcgtc catggcagta gtaaccgctg tgtcaaaacc aattgtaaag tcagtaccaa
     2341 cgatatcgtt atcgattgta cctggaagac caatagctgg gaagccatgt tcagtcaaac
     2401 gcatagcgcc gtggtaagat ccgtcaccac cgataacaac tacaccttca attccgtgtt
     2461 ttttcaattg ctcaatccct ttaagttgcc cttcaagttg agcgaactct ggataacgag
     2521 ctgagtgaag aaaagtacca ccacgagaaa tgatgtctcc tactgaagct gcatctaggg
     2581 gatgaatttc accggcaacc ataccagcat atccgtcata gataccaaac acttccattc
     2641 cttctgaaat tgcttgacga acaactgcac ggatagcagc gttcatacc
//
LOCUS       DAVAGB010000094         2650 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVAGB010000094 DAVAGB010000000
VERSION     DAVAGB010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2650
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.096"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            100..1593
                     /locus_tag="VQO19_002087"
     CDS             100..1593
                     /locus_tag="VQO19_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET1350285.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            1606..2148
                     /locus_tag="VQO19_002088"
     CDS             1606..2148
                     /locus_tag="VQO19_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET1350286.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLRDHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     FQLDELNLLVKSRYSEEVVA"
     gene            2145..>2650
                     /locus_tag="VQO19_002089"
     CDS             2145..>2650
                     /locus_tag="VQO19_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET1350287.1"
                     /translation="MKKVKLGQVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSKGIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIMVSYTNLREQQRIASELDLLSKLILRRQE
                     QLEELNLLV"
BASE COUNT          932 a          381 c          532 g          805 t
ORIGIN      
        1 tattcaggtg acgcatagat atagttaatt gaagctttgt ttgaaatctg ataaaataat
       61 gatattacta agttttaaaa actaaagaaa agggaagata tgattacagg cgaattaaaa
      121 aataaaatcg atcagttgtg ggaaattctt tggacagaag gaaatgcaaa tcctttaaca
      181 aatattgaac agttgactta tctcttattt atgaaagatt tggatagtgt tgagcttgga
      241 cgtgaaagtg atgctgaatt tctagggatt ccttatgagg gagtttttcc aaaagataaa
      301 cctgaatacc gttggtcaac ttttaaaaat ataggagatg ctcaggaagt ttatcgttta
      361 atgactcagg agatttttcc gtttattaaa aatctcaagg gggatacaga tgatacagcc
      421 ttttcacgat atatgcgaga agctattttt caaataaata aacctgctac gcttcaaaag
      481 gcaatttcta tcttagatgt ttttccaact aggggattag atgtagattt tgataatgac
      541 aaacaaagta ttactgatat cggagatatc tatgaatatc tgttatcaaa attgtcgacc
      601 gcaggtaaaa atggacagtt ccgtacacct cgtcacatca tcgatatgat ggttgagttg
      661 atgcaaccga ctatcaaaga tatcatctca gatcccgcta tgggttctgc tggcttctta
      721 gtatctgcta gccgttactt aaagcgtaag aaagatgaat gggaaaccaa tacagataat
      781 atcaatcatt ttcataatca gatgtttcat ggaaatgata cggatacgac tatgttgaga
      841 cttggggcga tgaacatgat gctacatgga gtagaaaatc cacaaatcag ttaccttgac
      901 tcgctgtctc aagataatga agaagccgat aaatatactt tggttttagc aaatcctcct
      961 tttaagggct cacttgacta caattcaacc tctaatgacc ttcttgcaac cgtaaaaacc
     1021 aaaaaaacag aattactctt tctttctctt ttcttgcgaa ctttaaaacc aggtggacga
     1081 gcagcagtta tcgtacctga tggtgtcctt tttggttcgt ctaaagctca taaaggaatt
     1141 cgtcaggaaa ttgtagagaa tcataagctt gatgctgtaa tctcaatgcc tagtggtgtg
     1201 ttcaagcctt atgctggagt ttcaactgcc attctcatct ttacaaaaac tggtaatggt
     1261 ggtactgaca aagtctggtt ttacgatatg aaagcggatg gtttaagttt ggatgataag
     1321 cgacaaccga ttagcgacaa tgatattcca gatattatcg aacgctttca tcatcttgaa
     1381 aaagaagcag aacgtcagag aacggatcaa tctttctttg ttccagttgc tgagataaag
     1441 gaaaatgatt atgatttgtc tatcaataaa tataaagaga ttgagtatga aaaagttgag
     1501 tatgaaccaa cagaagtcat attaaagaaa atcaatgatt tagaaaaaga aattcaagct
     1561 ggcttggctg aattggaaaa attactcaag tagggaggtg gctgtatgaa aaaagtgaag
     1621 ttgggggaag tcttatctct aaaaaaaggc aagaaagcca ctgtacttgc tgaacaaaca
     1681 actctaagcc aacgttatat tcaaatagat gatttaagaa ataataataa tttaaaattc
     1741 actgaaagtt taaatatgac tgaagcactc ccagatgata ttctgatagc atgggatgga
     1801 gctaatgcag gaacagttgg ttatggatta tcgggagctg ttggtagtac aattacggtc
     1861 ttaaaaaaga atgagcgata caaagaaaaa attatatcag attacttggg agtctttttg
     1921 gaaagtaaat cgcagtattt acgagatcat tcaacaggtg caacaattcc tcatttaaac
     1981 aagaatatat tacttgattt acaattagaa ttgctaggta tcgaagaaca agagaacatt
     2041 atctgtattc ttaatacgat taaaaggctt attactaaaa gaaaatttca gttagatgaa
     2101 ctaaacttgc tcgtcaaatc ccgatattcc gaggaggtgg ttgcatgaag aaagtgaaat
     2161 tagggcaagt ggctactttt atcaatggct atgcttttaa acctcaagat tggtcatctg
     2221 aagggaaaga gattatcaga atacagaatc tgactaaaac ttcaaaaggg ataaattatt
     2281 attcgggtac gattgataaa aaatacattg ttgaagctgg tgatattctt atttcgtggt
     2341 cgggtacatt aggggttttt cagtggtgtg gaagatccgc agtgttaaat cagcacattt
     2401 ttaaagtggt ttttgataag atagatatag ataaatcgta ttttaaatat gttgttgaaa
     2461 aaggtttgca agatgctgta aaacatactc atggttccac aatgaaacat ttaactaaaa
     2521 aatattttga taatattatg gtttcatata caaatttgag agagcaacaa agaattgcaa
     2581 gtgagctgga tttgttaagc aagctgattt taaggagaca agaacaactt gaagagctta
     2641 atctacttgt
//
LOCUS       DAVAGB010000095         2430 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVAGB010000095 DAVAGB010000000
VERSION     DAVAGB010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2430
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.097"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(<1..971)
                     /locus_tag="VQO19_002090"
     CDS             complement(<1..971)
                     /locus_tag="VQO19_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET1350288.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESSEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRK"
     gene            1595..1777
                     /locus_tag="VQO19_002091"
     CDS             1595..1777
                     /locus_tag="VQO19_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET1350289.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            1787..2152
                     /locus_tag="VQO19_002092"
     CDS             1787..2152
                     /locus_tag="VQO19_002092"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET1350290.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            2149..2430
                     /locus_tag="VQO19_002093"
                     /pseudo
     CDS             2149..2430
                     /locus_tag="VQO19_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811051.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
BASE COUNT          864 a          436 c          406 g          724 t
ORIGIN      
        1 attttacggc gagcaccaaa caactgctca ttttcagatg gtataccgta gtagaaacct
       61 gttgccaatt cacgttgggc aaccttccac atctcgtcca ctaagtcttg tttgatagct
      121 tcaaactttt cagaactttc aagataggca tccacagccg ccttgtagca gttggttact
      181 gttgatacgt agtgaataga cttcatacgt ccttcgattt ttagactgtc cacaccattt
      241 tcaatcatat ctggaatgtg gtcaatcata gacatgtcaa cggctgacat tgaaaattct
      301 tctggaatct caccctgcaa actcttacgt tctttcccaa atggcatatc gtaaaggtcg
      361 tatttccaac ggcatgactg agaacatcca ccacggttgg catcacgcat actcatgtgg
      421 tttgaaagag tacaacgtcc agagtatgaa atacacatag ctccatggac aaaggcttca
      481 atttcaacat ctgtacgttt gcggatctca gctaattctt ccattgaaac ctcacgcgct
      541 aaaacgacac gagtcaagcc tagctctttc cagaactcaa gggtttcata gttagtggca
      601 ctggcttggg tagaaaggtg gatttcaagg cctggtgctt cagtcgctgc aatcataatc
      661 aaggctgggt cagatacgat aactgctgca atcccgatat cacgcagttt acggaaccac
      721 tcaccagcac cagcttcatt tccttcgtgc ataaccatat tagccgctac atagaccttg
      781 gcaccatact tggccgcaaa ctgcacgcct tcttccatct gttcgaaagt aaagtttccc
      841 gcacggctac gaagaccata ggcctgacca ccgataaaga cagcatctgc tccatactga
      901 acagctacct ttagcttctc taaagtccct gcaggtgata aaacctcagg acgttttaat
      961 gtttttgtca taatttctcc tatttgcaat ataaaagttt gacatttttc cttctcattt
     1021 tatagtaaat aaaggataaa atcaagccta gacggattgt tttgacaatt ctaatctttt
     1081 agactttgca taataactat taaacagtcg aaaattaccc cagttttaac aagtagtcaa
     1141 aaagtctaaa aaagtaaaaa ccagtatccc aagatactga ctcgtaaaaa tatataaatt
     1201 agtccttaga tgactactcc cactctgttg ctcctataat ggaaaaggat tgatacagtc
     1261 tagaatatcg cttttttatt tattattatg atataaaact gttagaattg attttttgtt
     1321 ttatacccaa atatgaatag agacgtagct aataagttga ataacatatt tggaaaaatg
     1381 agaaatagca atattactag aacttttaga aacaatcaat atttaaaaag aaaaaagctc
     1441 aaagaattta ttaaaccatg ttataataga tatagctata attttattta taacaagagg
     1501 atagaaatga ccgaattaga aagaaaaaat cgaaaaatta gctaagaaat attctgataa
     1561 cttaaacatc aaagttcaag agagagttcg tgaaatggca aatgataata agagccatta
     1621 tttgatatac agagttttag gtatttcatt tgaagaagga gaaaatatcg atttgtatca
     1681 aaataaaggt cgttttttat acaaatatgc tggttcattt ttagaagaag ctgcagtact
     1741 atcctttaac gaaaaatttg gtacagaaaa tacttaaaaa gttaacattc ctaattctga
     1801 aagtacaaaa cctaagactt ttgaaattga ttgtttagtc ggagaaaaac acgcatacga
     1861 aataaaatgg tgggatgcaa ctacagatgg agaccatata actaaagaac acactagaat
     1921 aaaagttatt cataacaaag gatatatacc aattcggtta atgttctact atccaaatag
     1981 aactcaagct ataaaaattc agcaaacttt agaaacattg tataacggta ttggagggaa
     2041 atattattat ggagattctg cctgggaaca tttaagagca gtgaccggta ttgatttact
     2101 tagtattcta acagatattg caaataaaaa aacaggggta aaatcaaaat gacagtatta
     2161 aaaggagata acttagaaat attaaaaact attgaatcct caagtattga tttaatctat
     2221 atggaccctc ctttctttac acagaaaacc caaaaattat ctaataacaa aaatattatg
     2281 tattcattcg aagatacgtg gacttcgatt gaggattaca aagaattttt gtctgtaaga
     2341 ttagaagaat gcaaaagagt gctaaaaaat agtggcagta tttcgttcat tgtgataaaa
     2401 ttgcaaatca tcatattaga ttaattttag
//
LOCUS       DAVAGB010000096         2324 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVAGB010000096 DAVAGB010000000
VERSION     DAVAGB010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2324
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.098"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(1..476)
                     /locus_tag="VQO19_002094"
                     /pseudo
     CDS             complement(1..476)
                     /locus_tag="VQO19_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(421..603)
                     /locus_tag="VQO19_002095"
     CDS             complement(421..603)
                     /locus_tag="VQO19_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET1350291.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            938..>2324
                     /gene="pcpA"
                     /locus_tag="VQO19_002096"
     CDS             938..>2324
                     /gene="pcpA"
                     /locus_tag="VQO19_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HET1350292.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNRGV"
BASE COUNT          810 a          347 c          381 g          786 t
ORIGIN      
        1 tcgcttgagc cttcatagcg tgaaatttct ttttaccaga atgattcgct aattgttttt
       61 ttagggcgat tgatttgtac ttccgtcgca tcaatcatta ccgtgtcctc agagctgaga
      121 ggagtttttg aaatcgtaac accactttga acaagagtta cttcaaccca ttggctccga
      181 cggattaagt tgctttcgtg gataccaaaa tcagccgcaa tttcttcata agtgcggtat
      241 tctcacacat attgaagagt ggccataaga aggtcttcta ggcttaattt aggttttcgt
      301 ccaccttttg cgtgtttaag ttgataatct gtttttaata cagctaacat ctctttaaaa
      361 gtcgtgcgct gaacaccaac aagacgctta aatcgtgtat cagttaattg tttacttgct
      421 tcataatttc gcagggagtc tattgactct ttggtaggtg tcaatgtttt tttcatctat
      481 cccgagaatt attttcccgc catttgtatt tgcaaatgct gagtaggttt cccagaaaga
      541 ctctggaaga ttgtttttag cttttttgta ttctaaatca accccttcaa attttaagtc
      601 catatttttc ctttacatct gttttttgtg gttctggtat ttgttcaagt tgagtgataa
      661 tatagcgaat tgaatttcga gagtttttac tcagttaatt tcttttttaa cccactttaa
      721 tttctttttt aatacgggtt aaaaaagaaa ttaaagtggg ttaattttcc ttgacttaaa
      781 atttaaaaat gatatactgt gtttatggag agatgacaat ttataaaatg tactactcta
      841 ttctactaga taatgattga ataaaacttt ttataacaac ggctagcaaa gttataattt
      901 tatatctatt agaaaataaa tatgtaagga aatttaaatg aaaaaaacta caatattatc
      961 attaactaca gctgcggtta ttttagcagc atatgtccct aatgaaccaa tcctagcaga
     1021 tactcctagt tcggaagtaa tcaaagagac taaagttgga agtattattc aacaaaataa
     1081 tatcaaatat aaggttctaa ctgtagaagg taacatagga actgttcaag tgggtaatgg
     1141 agttactcct gtagagtttg aagctggtca agatggaaaa ccattcacga ttcctacaaa
     1201 aatcacagta ggtgataaag tatttaccgt tactgaagta gctagtcaag cttttagtta
     1261 ttatccagat gaaacaggta gaattgtcta ctatcctagc tctattacta tcccatcaag
     1321 cataaaaaaa atacaaaaaa aaggcttcca tggaagtaaa gctaaaacta ttatttttga
     1381 caaaggcagt cagctggaga aaattgaaga tagagctttt gatttttctg aattagaaga
     1441 gattgaattg cctgcatctc tagaatatat tggaacaagt gcattttctt ttagtcaaaa
     1501 attgaaaaag ctaacctttt cctcaagttc aaaattagaa ttaatatcac atgaggcttt
     1561 tgctaattta tcaaatttag agaaactaac attaccaaaa tcggttaaaa cattaggaag
     1621 taatctattt agactcacta ctagcttaaa acatgttgat gttgaagaag gaaatgaatc
     1681 gtttgcctca gttgatggtg ttttgttttc aaaagataaa actcaattaa tttattatcc
     1741 aagtcaaaaa aatgacgaaa gttataaaac gcctaaagag acaaaagaac ttgcatcata
     1801 ttcgtttaat aaaaattctt acttgaaaaa actcgaattg aatgaaggtt tagaaaaaat
     1861 cggtactttt gcatttgcgg atgcgattaa acttgaagaa attagcttac caaatagttt
     1921 agaaactatt gaacgtttag ccttttacgg taatttagaa ttaaaagaac ttatattacc
     1981 agataatgtt aaaaattttg gtaaacacgt tatgaacggt ttaccaaaat taaaaagttt
     2041 aacaattggt aataatatca actcattgcc gtccttcttc ctaagtggcg tcttagattc
     2101 attaaaggaa attcatatta agaataaaag tacagagttt tctgtgaaaa aagatacatt
     2161 tgcaattcct gaaactgtta agttctatgt aacatcagaa catataaaag atgttcttaa
     2221 atcaaattta tctactagta atgatatcat tgttgaaaaa gtagataata taaaacaaga
     2281 aactgatgta gctaaaccta aaaagaattc taatcgggga gtag
//
LOCUS       DAVAGB010000097         2109 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVAGB010000097 DAVAGB010000000
VERSION     DAVAGB010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2109
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.099"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            <1..358
                     /locus_tag="VQO19_002097"
     CDS             <1..358
                     /locus_tag="VQO19_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HET1350293.1"
                     /translation="YIIDFEHALRKETQIEEKKLPLFGTPGFYETNLNLLNNQPEDIM
                     GLVLLLYWSQNLDDFNVFSKMSFLEAMEYAMNFNSRRLDTLDKSDWLYDIYKKAFNYK
                     YDTFSELKKDFIEVLK"
     gene            372..1289
                     /locus_tag="VQO19_002098"
     CDS             372..1289
                     /locus_tag="VQO19_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000995574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET1350294.1"
                     /translation="MNCFLKMNNVSVRYDDVIALKDITLQINKGDFIGLLGSNGAGKS
                     TLINSIVGFQEIYLGEIEYCDKDLIVSSQPFAHLGFTPQTTVIDFYTTVKDNVILGLN
                     LAGKFGKNAEKLCQIALEIVGLADKKNNLVETLSGGQLQRVQIARAIAHNPDFYILDE
                     PTVGLDTESAEKFLMYLKDKSLEGKTIIISSHDINLLEKFCKKILFLQNGSISFFGDM
                     RDFVDNSTIKLNFSMQNRISRYQIEFLENFRFKVHIEDNDSFTIEVPIEENILDVINE
                     VGKACEIKNFSTSKLTLQESYLQRIGGEK"
     gene            1286..2086
                     /locus_tag="VQO19_002099"
     CDS             1286..2086
                     /locus_tag="VQO19_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET1350295.1"
                     /translation="MKADQLRHKSDLGLRGLAIIAKNEIIAFFRSKGLIISQFLQPIL
                     YVVFIIIGLNSSIKNIQFNDIKTSYAEYTIIGVIALLIIGQMTQVIYRVTIDKKYGLL
                     ALKLCSGVRPLYYILGMSIYSILGLIVQEIIIYIITLAFEINIAMDRFFYTVLLSIVV
                     LLFWDSLAILLTMFINDYRRRDIVIRFVLTPLGFTAPVFYLIDSAPSIVRWIGQLNPL
                     TYQLTILRNFYFKNSTTLELVFLLLTSLLVLISVSFIIPKIKLILIER"
BASE COUNT          731 a          244 c          362 g          772 t
ORIGIN      
        1 ttatattata gactttgagc atgccctaag gaaagaaact caaattgaag aaaaaaagtt
       61 gcctctattt ggaactccag ggttttatga aaccaactta aatttattga ataatcaacc
      121 agaggatatt atgggattgg ttttgttatt atattggagt cagaatttag atgattttaa
      181 cgtcttttca aaaatgagtt ttttagaagc gatggagtat gcaatgaatt ttaattcgcg
      241 tcgcttagac acacttgata aatcagattg gctttatgat atttataaaa aagcgttcaa
      301 ttataaatat gatacttttt ctgaattaaa aaaagatttt atagaggtat taaaataaag
      361 gtaggggtgt tatgaattgt ttcttgaaaa tgaataatgt aagtgttcgt tatgatgacg
      421 taatagcttt aaaagatata actttacaaa taaataaggg agatttcatt ggcttattag
      481 gttcaaatgg tgcaggtaaa tctacgttaa ttaattctat tgtaggtttt caagagattt
      541 atttaggaga aatagagtat tgtgataaag atttgatagt tagttctcaa ccttttgctc
      601 atttaggctt tactcctcaa accacagtaa ttgattttta tactactgtg aaggacaatg
      661 taatattggg gctgaacctt gctggaaagt ttgggaaaaa tgctgagaag ttgtgtcaaa
      721 tagccttaga aattgttggg ttagctgata aaaaaaataa tttggtagaa acattgtcag
      781 gtggacaact gcaacgcgtc cagattgcta gagcaatagc tcataatcca gatttttata
      841 ttttagatga acctaccgtt ggtttagata ctgaatctgc cgaaaaattt ttaatgtatt
      901 taaaagataa gagtttggaa ggaaaaacta ttatcatatc ttcacatgac ataaatctac
      961 tcgaaaagtt ttgtaaaaaa atactttttt tacaaaatgg ctccatatca ttttttggtg
     1021 atatgcgtga ctttgtagat aattcaacta tcaaattaaa tttttcaatg cagaatagaa
     1081 tttctagata tcaaattgaa tttttagaaa attttagatt taaagttcac atcgaagata
     1141 atgatagttt tacaatagaa gtccctatag aagaaaatat cttagatgtt atcaatgagg
     1201 taggaaaagc atgtgaaatt aaaaactttt caacaagtaa attaacctta caagaaagtt
     1261 atttgcaaag aataggagga gaaaaatgaa ggctgatcaa ttaaggcaca aatcggactt
     1321 aggtttaaga ggtctagcga ttattgctaa aaatgagatt attgcttttt ttagaagtaa
     1381 aggtttaatt atttctcagt ttctacaacc aatcttatat gttgttttta taataatagg
     1441 attaaattct tcgataaaga acattcagtt taatgatata aaaacctctt atgcagaata
     1501 tacaatcatt ggtgttatag ctttattgat aatcgggcag atgactcaag ttatttatag
     1561 ggtgacaata gataaaaaat atgggctact tgctcttaag ttatgcagtg gagttcgtcc
     1621 tttatattat attttaggga tgagtatcta ttctatatta gggttgatag ttcaagaaat
     1681 tattatatat ataattacgt tagcgtttga gataaatatc gcaatggata gattttttta
     1741 tacagttttg ttatctattg ttgttttatt attttgggac tcccttgcaa ttttacttac
     1801 aatgtttatc aatgattaca gaagacgtga tattgtaata cgttttgtac taacaccgct
     1861 tggttttaca gctcctgttt tctacttaat agattctgct cctagtattg tgagatggat
     1921 tggtcagtta aatcccttaa cttatcaatt aactattttg agaaactttt attttaaaaa
     1981 ttcaacaact ttggaattag ttttcttatt gttaacatca ttacttgtcc ttatatctgt
     2041 atcttttatt ataccaaaga taaaattgat actgatagaa agataaaagt tgggtcatcc
     2101 aactttttt
//
LOCUS       DAVAGB010000098         2039 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVAGB010000098 DAVAGB010000000
VERSION     DAVAGB010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2039
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.100"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            <1..476
                     /locus_tag="VQO19_002100"
     CDS             <1..476
                     /locus_tag="VQO19_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET1350296.1"
                     /translation="SHEYKAIKRYWKLIQQDSRKLSDKRFYRPTFRMHLTNKEILNKL
                     LSYSEDLKHHYQLLLFHFQNKEPEKFFELIEDNLKQVHPIFQTVFKTFLKDKEKIINA
                     LQLPYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(610..697)
                     /locus_tag="VQO19_002101"
     tRNA            complement(610..697)
                     /locus_tag="VQO19_002101"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(661..663),aa:Ser,seq:gct)
     gene            complement(704..777)
                     /locus_tag="VQO19_002102"
     tRNA            complement(704..777)
                     /locus_tag="VQO19_002102"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(741..743),aa:Ile,seq:gat)
     gene            complement(813..883)
                     /locus_tag="VQO19_002103"
     tRNA            complement(813..883)
                     /locus_tag="VQO19_002103"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(849..851),aa:Gly,seq:tcc)
     gene            complement(903..975)
                     /locus_tag="VQO19_002104"
     tRNA            complement(903..975)
                     /locus_tag="VQO19_002104"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(940..942),aa:Phe,seq:gaa)
     gene            complement(979..1052)
                     /locus_tag="VQO19_002105"
     tRNA            complement(979..1052)
                     /locus_tag="VQO19_002105"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1016..1018),aa:Met,seq:cat)
     gene            complement(1066..1155)
                     /locus_tag="VQO19_002106"
     tRNA            complement(1066..1155)
                     /locus_tag="VQO19_002106"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1117..1119),aa:Ser,seq:tga)
     gene            complement(1166..1239)
                     /locus_tag="VQO19_002107"
     tRNA            complement(1166..1239)
                     /locus_tag="VQO19_002107"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1203..1205),aa:Ile,seq:cat)
     gene            complement(1253..1326)
                     /locus_tag="VQO19_002108"
     tRNA            complement(1253..1326)
                     /locus_tag="VQO19_002108"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1290..1292),aa:Met,seq:cat)
     gene            complement(1332..1405)
                     /locus_tag="VQO19_002109"
     tRNA            complement(1332..1405)
                     /locus_tag="VQO19_002109"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1369..1371),aa:Pro,seq:tgg)
     gene            complement(1421..1494)
                     /locus_tag="VQO19_002110"
     tRNA            complement(1421..1494)
                     /locus_tag="VQO19_002110"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1458..1460),aa:Arg,seq:acg)
     gene            complement(1504..1589)
                     /locus_tag="VQO19_002111"
     tRNA            complement(1504..1589)
                     /locus_tag="VQO19_002111"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1553..1555),aa:Leu,seq:taa)
     gene            complement(1597..1668)
                     /locus_tag="VQO19_002112"
     tRNA            complement(1597..1668)
                     /locus_tag="VQO19_002112"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1634..1636),aa:Gly,seq:gcc)
     gene            complement(1691..1763)
                     /locus_tag="VQO19_002113"
     tRNA            complement(1691..1763)
                     /locus_tag="VQO19_002113"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1728..1730),aa:Thr,seq:tgt)
     gene            complement(1782..1863)
                     /locus_tag="VQO19_002114"
     tRNA            complement(1782..1863)
                     /locus_tag="VQO19_002114"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1827..1829),aa:Leu,seq:tag)
     gene            complement(1869..1941)
                     /locus_tag="VQO19_002115"
     tRNA            complement(1869..1941)
                     /locus_tag="VQO19_002115"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1906..1908),aa:Lys,seq:ttt)
     gene            complement(1966..2038)
                     /locus_tag="VQO19_002116"
     tRNA            complement(1966..2038)
                     /locus_tag="VQO19_002116"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2003..2005),aa:Asp,seq:gtc)
BASE COUNT          605 a          533 c          407 g          494 t
ORIGIN      
        1 aatcccatga atacaaggct atcaagcgct actggaagct catacaacag gatagtcgta
       61 aactgagtga taagcgattt tatcgtccta cttttcgtat gcacttaacc aataaagaga
      121 ttttaaacaa gcttttgagt tattcggaag acttgaaaca ccactatcag ctcttacttt
      181 ttcacttcca gaataaggaa ccagagaaat ttttcgaact tattgaggac aatcttaagc
      241 aggttcatcc tatttttcag actgtcttta aaaccttcct caaagataaa gaaaagatta
      301 ttaacgccct tcaactaccc tattctaatg ccaaactgga agcgaccaat aatctcatca
      361 aacttatcaa gcgcaatgcc tttggatttc ggaactttga aaacttcaaa aaacggattt
      421 tcatcgcttt gaacatcaaa aaagaaagga caaaatttgt cctttctcga gcttagcttt
      481 tcttcaaccc actacagttg acaaagagcc ataaaaataa cttcagatta gtaattcaat
      541 taagttttac ggatctgaag ctttattgtc tctaaaaata aaaaagagag ttacaaactc
      601 tcattaaaac ggagaataag ggattcgaac ccttgcgcca gttacccgac ctaacgattt
      661 agcaaaccgt cctcttcagc ctcttgagta attctccaat taatgggcac gagtggactc
      721 gaaccaccga cctcacgctt atcaggcgtg cgctctaacc acctgagcta cgcgcccaag
      781 ttaaaaaact tggtaatttg aacaaagttc aaagcgggtg acgagaatcg aactcgcgac
      841 aacagcttgg aaggctgtag ttttaccact aaactacacc cgcataaata ctatcaataa
      901 aatggcgcga gacggaatcg aaccgccgac acatggagct tcaatccatt gctctaccaa
      961 ctgagctacc gagccttatt gcgggagcag gatttgaacc tacgaccttc gggttatgag
     1021 cccgacgagc taccgagctg ctccatcccg cgttaataat ataaaaggag gatgtgggat
     1081 tcgaacccac gcacgctttt acacgcctga cggttttcaa gaccgttccc ttcagccgga
     1141 cttgggtaat cctccaatat tcaaatggac cttgtaggac ttgaacctac gaccactcgg
     1201 ttatgagccg agagctctaa ccagctgagc taaaggtcca acaagatcat tatagcggcg
     1261 aaggggatcg aacccccgac ctcccgggta tgaaccggac gctctagcca gctgagctac
     1321 accgccatga atcgggaaga caggattcga acctgcgaca ccttggtccc aaaccaagta
     1381 ctctaccaag ctgagctact tcccgagtta aatagaaaaa tgcaccctag aggagtcgaa
     1441 cctctaaccg cctgattcgt agtcaggtac tctatccagt tgagctaagg gtgctccata
     1501 ttatgccgag gaccggaatc gaaccggtac gatcgttacc aatcgcagga ttttaagtcc
     1561 tgtgcgtctg ccagttccgc caccccggcc tctctaagcg aacgacggga ttcgaacccg
     1621 cgacccccac cttggcaagg tggtgttcta ccactgaact acgttcgcac tgttttcttc
     1681 tatctaaaaa tgccggctac atgacttgaa cacgcgaccc tctgattaca aatcagatgc
     1741 tctaccaact gagctaagcc ggctcatttg ttatatctta atgcgggtta agggacttga
     1801 acccccacgc cgttaagcgc cagatcctaa atctggtgcg tctgccaatt ccgccaaacc
     1861 cgcatatatg acccgtactg ggctcgaacc agtgacccat tgattaaaag tcaattgctc
     1921 taccaactga gctaacgagt ctaaaataac ttgcgttacc ttaaacggtc ccgacgggaa
     1981 tcgaacccgc gatcttcgcc gtgacagggc gacgtgataa ccgctacact acgggacct
//
LOCUS       DAVAGB010000099         1860 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVAGB010000099 DAVAGB010000000
VERSION     DAVAGB010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1860
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.101"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(97..1233)
                     /gene="lctO"
                     /locus_tag="VQO19_002117"
     CDS             complement(97..1233)
                     /gene="lctO"
                     /locus_tag="VQO19_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HET1350297.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
BASE COUNT          562 a          412 c          329 g          557 t
ORIGIN      
        1 ctattcttat ttcatttcac tatagttttc gatagcaatt tattcttcca atacacgaag
       61 aaaaacctcc acattcagtg gaggcaatct gttttatcaa tacaatttta agtcacgagg
      121 gtcaactggg aaggttgggt tgtatggatt gtgacggagc ttaaagtgtt tgacatcttc
      181 aatggtctga gctccagaca attgcataac tgtcttcaat tccgcattca agtgttcaaa
      241 gacttgacgc acaccgacac taccaccgag agctaagcca taaataacag ggcgaccaat
      301 agctaccaag tctgctcctg aagccaaggc tttaaagacg tgttgaccac gacgaacacc
      361 agagtcaaag acaatcggca cacgtctatc aactgcttct gccacttctt gaagcgagtc
      421 aaaggcagct ggtccaccgt cgatttgacg accaccgtgg ttggttaccc agataccaga
      481 agctcctgca gcaagtgaac gttcaacgtc ctcacggcat tgtggtccct tgacatacac
      541 aggaagacca gagtattcag cgataaattc tacatcgcgt ggagacaagc gttgtttagc
      601 tgatttgtaa acaaagtcca ttgatttacc agcaccttct ggcaggtatt cttcaacaat
      661 cggcatgcca actgggaaga caaaaccatt acgcttatcc acttcacgat tcccccctac
      721 agtagcatct gccgtcaaga caatcgcttt ataaccttca gccttcacac ggtccatgat
      781 gtggcggttg ataccgtcat ccttactaaa gtaaaattgg aaccaatggg gtgtcccttg
      841 aagggcttca gaaatctctg gaaggtcaac agtagagtaa gagctggttg tataaagaga
      901 accaaactca tgcacaccac gcgcagtcgc cacttccccc tgttcatttg ccaatttatg
      961 agccgcaaca ggcgccataa tgattggtga agatagtttt tcacctgcaa attcaatctc
     1021 tgtacttgga ttttcaacat cgcaaagtgt atgaggaacg atgagtttgt ggttaaaggc
     1081 gcggatattc tctcttaaag tgaaagtatc ttccgcccca ctagcgatat agccaaatgc
     1141 tgctttagga ataacttgtt gcgccattgg ctccaaatca taggtattga tgaagtctac
     1201 atgaccttct gcattgcttg ttttatatga cataaaatgc cctccttgat taagtaagcg
     1261 tttgcttttt actacacaac tataataact cttttttcaa tcattttcaa gagttttgct
     1321 taaaaaccat cttatttttt catacaatat actagcccta ctttccttaa actctaaacc
     1381 ttagtctata ttaagtgaat cgttgagatt ttttgctgcc aggcatttga actacttttt
     1441 tatttgcgga ttctatctac taatactata aaaaaaacaa gtgaataaga caccagaaca
     1501 tcctctaata ggacctatgg acttatatca gtcccatata tactgtttaa gcaagatact
     1561 atcctagttg acgctaactt cctatcccac ttattaattt tttatttata gtgaatctga
     1621 acaaatcaat tggggaatcc aagtcaattt ctagtacttt ttgaacagtt tcagcgtact
     1681 atcgtaaaat gaaataaaac atgcacaaat tgattaggga atttaaacca atttctaaca
     1741 atgtcttaga aatcaaagtg tactatttca acttcaatat actacacttc attttctcct
     1801 taaattcagt ctctttttga atcaaaaaat cctctggtaa gagccagagg gtaagaattt
//
LOCUS       DAVAGB010000100         1857 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVAGB010000100 DAVAGB010000000
VERSION     DAVAGB010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1857
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.102"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            62..513
                     /locus_tag="VQO19_002118"
                     /pseudo
     CDS             62..513
                     /locus_tag="VQO19_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            678..977
                     /locus_tag="VQO19_002119"
     CDS             678..977
                     /locus_tag="VQO19_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HET1350298.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            1113..1857
                     /locus_tag="VQO19_002120"
                     /pseudo
     CDS             1113..1857
                     /locus_tag="VQO19_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          670 a          326 c          364 g          497 t
ORIGIN      
        1 tgtactattt ttggttcatt tcactataat aataacgata ctagataatg aggaaaatgc
       61 aatggcaaac ccaactttcg gagaaaaaaa gtgaatacag actatattgc tcgctatggc
      121 gtatatgcag ttatccctaa tcctgaacaa aaacaaattg ttcttgttca agaaccaaat
      181 ggtgcttggt tcctaccatg tggaaaaatt gaagcaggtg aaaatcatca ggaagcccta
      241 aagcgtgagt tgattgaaga gcttggtttc acagcagaaa ttggtaccta ttacggacca
      301 gctgacgaat atttctattc tcgtcatcgt gatacctact actacaatcc tgcctacctc
      361 tatgaagcaa ctcctttcaa agaagtacaa aagccactag aaaactttaa tcatattgcc
      421 tggttcccta ttgacgaggc tatcaaaaac cttaaacgtg gcagccataa atgggccatt
      481 gaatcttgga aaaaacagca taagattggc taatactctt cgaaaataaa attcaaatca
      541 cgtaagcgtc gccttaccgt actcaagtat agcctgcggc tagcttctta gtttgctctt
      601 tgattttcat tgagtataaa tcaagcgact ttattcaaaa agtgttataa tagaattaga
      661 aaatcggagg aaatattatg aagcttatca atacgacaaa ctcacactcg caacttgtaa
      721 aaagtcaact agaaagtacc gatgcaaccc ttgttgaggt ttattctgca gggaatacag
      781 atgttatttt tacccaagct ccgcttcact atgaaatcct catctcaaac aaacaccgtg
      841 ctattcgtga gcctgaaatc gaaaccattc aagaattttt cttgaaacgt aaaattgata
      901 agacctctgt tgatgaagcc aatatcaaga cactctactc agagaaatta attggaattt
      961 caatcccaat caagtaagaa aattgagtaa aaactcgatt tgagagaaag tccaataagt
     1021 ctttccataa caaaacgcat agtatcaggt gccgaaatga actgccccct aaaagttaga
     1081 cagaaaaaat ctaacttttg gggtgtttta ttatgaaatt aagttatgaa gataaagttc
     1141 agatctatga actaagaaag caaggacaaa gcttcaaaca gctttcaaaa agatttggtg
     1201 tggatgtttc tggtctaaag tacatggtga aattaattga ccgtcatggc atagaaatcg
     1261 ttaaaaaggg gaagaatcgt cactattctt ctaaattgaa acaagaaatg atggataaag
     1321 ccttactgga aggttgttca caaagaagtg ttagtcttga ttatgccctc ccaaaccaag
     1381 gaatgctttc attttggctg gcacaataca agaaaaacgg gtatactatt gttgagaaaa
     1441 caagagggag accagctaaa atgggacgta aacggaagaa gacttgggaa gaaatgacag
     1501 aactagaacg actccaggag gagaatgaac gcttacggac tgaggtggcc tacctaaaaa
     1561 agttaaaaga gttagaggaa agggacgaag ccctagagcg agaaaggcag agacagttag
     1621 agaaatggtt tcaggaggat ttcgactaga ttttcttctt gaaacagcac gtttagctcg
     1681 ctcgacttac tattatcagt tgaaacaact ggatggggtt gataaagata aagagattaa
     1741 aacctaaatt caggccattt ataatgaaca taaaggcaac tatggttatc gtcggattta
     1801 tttagaacta agaaatcgtg gttatctggt aaatcataaa agagttcaac acttgat
//
LOCUS       DAVAGB010000101         1822 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVAGB010000101 DAVAGB010000000
VERSION     DAVAGB010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1822
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.103"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            <1..203
                     /locus_tag="VQO19_002121"
     CDS             <1..203
                     /locus_tag="VQO19_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HET1350299.1"
                     /translation="DAVMVKDVNEDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFR
                     IPAMSAPVFDNIEAAIKEHGLS"
     gene            251..1726
                     /locus_tag="VQO19_002122"
     CDS             251..1726
                     /locus_tag="VQO19_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HET1350300.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNIVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
BASE COUNT          514 a          370 c          370 g          568 t
ORIGIN      
        1 gtgatgcagt catggtgaaa gatgtaaacg aagaccttat gaaaggttac gatatcttta
       61 caccaatcgc tgcaacagac cttggttttg aaccaggtat cccagttatc gaagctgggc
      121 caatcttatt ccgtatccca gcaatgagcg ctccagtatt tgacaatatt gaagcagcta
      181 ttaaagaaca cggattaagc taattctaat ttgttaacat tcatataaca taaaaaaggg
      241 aggaactgtt atggatgcaa tctttgacct aatcggaaag gttttcaatc ccattttaga
      301 aatgggtgga cctgtcatca tgttaatcat tttgacagta ttggctttac tttttggagt
      361 gaaattctcc aaagcgcttg aaggtggtat caaacttgcc atcgctctta caggtatcgg
      421 tgctatcatc ggtatgctaa atggtgcttt ctcagcatca cttgcaaaat tcgttgaaaa
      481 cactggtatc caattgagta ttaccgacgt tggttgggca ccactcgcaa caatcacttg
      541 gggttctgct tggacactat acttcttgct catcatgttg attgtcaaca tagtgatgct
      601 agctatgaag aaaaccgata cacttgatgt cgatatcttt gatatctggc acttgtctat
      661 cacaggtctc ttgattaaat ggtatgctga taacaatggt gtgagtcaag gggtttcact
      721 ctttattgct acagcagcta tcgttcttgt cggtgtgttg aaaattatca actctgactt
      781 gatgaaacct acatttgatg accttcttaa cgccccaagt tcatcaccaa tgacatcaac
      841 tcacatgaac tacatgatga acccagttat catggttttg gataagattt ttgaaaaatt
      901 cttcccaggc cttgataaat atgactttga tgctgctaaa ttgaacaaga aaatcggttt
      961 ctggggatct aaattcttca tcggtttcat ccttggtatc gttatcggta ttatgggaac
     1021 tccacatcca attgcaggtg ttgcagatgc agataaatgg cgtcttgtta tcaaaggatg
     1081 gttgtctctt ggtttgactg ccggtgtatc tttggaactc ttctcactta tcggttcatg
     1141 gttcatcgca gccgtagaac cactatcaca aggtattaca aacgttgcta ctaaacgtct
     1201 tcaaggacgt aaattcaata ttggtcttga ctggccattc atcgctggtc gtgctgaaat
     1261 ctgggcttgt gccaacgtac ttgcaccaat catgttgatt gaagcagtgc ttctttcaaa
     1321 agttggaaat ggtatcttgc cacttgcagg tatcatcgct atgggtgtta ctccagctct
     1381 cttggttgta actcgtggta aattgctccg tatgattatc ttcggaacac tcttgttgcc
     1441 actcttcctt ctttcaggta cccttattgc accatttgca acagaacttg ctaaaggtgt
     1501 aggtgccttc ccagaaggtg tgagccaaac tcaattgatt actcactcta ctcttgaagg
     1561 accaatcgaa aaacttcttg gttggacaat tggtaacact acaactggtg atatcaaagc
     1621 aatccttggt gcagtagcct tccttgtatt ctatatcggt atctttgctt ggtacagaaa
     1681 acaaatgatc aaacgtaacg aagagtacgc agcaaaagca aaataatgcg ctcctataaa
     1741 atataaactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaggt tgctcaaaac
     1801 acagttttga ggttgtagat aa
//
LOCUS       DAVAGB010000102         1750 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVAGB010000102 DAVAGB010000000
VERSION     DAVAGB010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1750
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.104"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            <1..854
                     /locus_tag="VQO19_002123"
     CDS             <1..854
                     /locus_tag="VQO19_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET1350301.1"
                     /translation="QRIVEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAM
                     QGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNSYYEEVPC
                     EIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLARFIDPETV
                     HSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYAWAVADSHVTVIRVLSGVINC
                     HFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIPLPPLPEQSRIVDKIEQFF
                     AHIDALI"
     gene            911..1708
                     /gene="psrA"
                     /locus_tag="VQO19_002124"
     CDS             911..1708
                     /gene="psrA"
                     /locus_tag="VQO19_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HET1350302.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
BASE COUNT          636 a          246 c          316 g          552 t
ORIGIN      
        1 aacaacgaat agtagaagca atcgaatcag ctttagaaaa agtagatgaa tatgctgaaa
       61 gttataatag actagaacag ctagataaag aatttccaga taaactaaaa aaatctattc
      121 ttcaatatgc tatgcaagga aaattagttg aacaagaccc aaatgatgaa tcagtcgaag
      181 ttttacttga aaaaatacga gcagaaaaac aaaaactctt tgaagaaggc aagattaaaa
      241 agaaagattt ggacatttct attgtttccc aaggagatga taactcttat tatgaggaag
      301 taccttgtga aataccagaa agttgggaat gggtgaggtt aaacgatata acctcctaca
      361 ttcaaagagg gaagtctcca aaatattcaa atattcctat ataccctgtg attgctcaga
      421 aatgtaatca atggtctggc ttttctattg acttagcaag atttattgat cccgaaacag
      481 ttcatagtta ccagaaagaa agattactaa gggatggtga tttaatgtgg aattcaacag
      541 gtctaggtac gttaggacga ttagctattt accatgaaaa taaaaatcct tatgcctggg
      601 ctgttgcaga tagccatgtt acagttataa gagtcttatc gggggttatt aattgccatt
      661 tcatctataa ttttctttcc tctcctattg ttcagtcagt tattgaagaa aaagcgtcgg
      721 gtagtacaaa acaaaaagaa ttattaacga aaactataaa agaatattta atccccctcc
      781 caccccttcc tgaacaatcc agaatcgttg ataaaatcga acaatttttc gcccatattg
      841 acgcactaat ttagtataat agttttacgt gcggtggaat ttctatcaaa cataagatag
      901 gagttttacg ttgaaagatt ttgaattaca tttgaagaaa gctggtttag ctgaaaatac
      961 tgtgcgttcg tacctttatg gtgttcgatt tttcttggag aattacgaac tcaaaatgga
     1021 agatttattt gaatacaaag gatatttatt agacaatttt aaacctaaaa ctgtcaattt
     1081 gcgactacaa ggagtaaata aatatctggc ttttattggt catgatgatt tgaaattaaa
     1141 atttgtcaaa gtacagcaaa aaccgttttt agaagatgtc attagccatg ctgattacct
     1201 ttttcttaaa cgtagtttga aaaaagatgg tattttaaaa tggcattttg tcgtttggtt
     1261 tttaggtgca actggggctc gtgtaagtga acttattaaa ctaaaagtag agcatgtaga
     1321 aatcggttat tttgacattt actcaaaagg tggtaaaatt cgtagactgt acattcctaa
     1381 aaaattaaga aatagttgtc ttagttggtt agaatcagaa aatcgtcgaa gtggttattt
     1441 atttttgaat aaatttaacg aaccaattac agcaagagga gttgctcaac agttaaaaaa
     1501 ttatgctgat aaatacaaaa tgaatcctaa agtaatttac cctcattctt ttaggcattt
     1561 atttgctaag aattttttag cgaagtataa tgatattgcc ttgcttgcag atttgatggg
     1621 acacgaaagt atagaaacta ctcgaattta tctaaggaaa acagctactg aacaacaaaa
     1681 tattgtagat aaaattgtta attggtaaaa aataacaggt ggtcaaactg actacctgct
     1741 atttttgtga
//
LOCUS       DAVAGB010000103         1727 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVAGB010000103 DAVAGB010000000
VERSION     DAVAGB010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1727
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.105"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            337..1683
                     /gene="gdhA"
                     /locus_tag="VQO19_002125"
     CDS             337..1683
                     /gene="gdhA"
                     /locus_tag="VQO19_002125"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HET1350303.1"
                     /translation="MTSAKEYIQSVFETVKTRNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGILYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDDRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
BASE COUNT          531 a          327 c          340 g          529 t
ORIGIN      
        1 actattatat atactttttt attttagtct agtataaata ttgctttcct ccaaaatggt
       61 catagtttta ctggcaaatc taacatatca cggataaatt aacaagtgat ttctgaattg
      121 ctaaacattt tcttttctta tagcatacca tactttaaga ttttgtcttt gagaaagata
      181 tttccaagaa aaacgttcgt ttttttatct attttcaaaa aacccaaaaa ctgaattgaa
      241 agaattttta gaaaatttct gttttttctt tacagtgaaa aaaaattctg ctataatgtc
      301 ttatgtaata aaatatgaca ataaaaggag aacgatatga catctgctaa agaatatatc
      361 caaagcgtgt tcgaaactgt aaaaactcgt aacgggcacg aggctgaatt cctccaagct
      421 gttgaagaat ttttcaacac tttggaacct gtatttgaaa aacaccctga gtatatcgaa
      481 gaaaatatct tggcacgtat tactgagcct gagcgcgtgg tttctttccg tgttccttgg
      541 gttgaccgtg atggaaaaat tcaagtaaac cgtggttacc gtgttcaatt caactcagct
      601 gttggaccat acaaaggtgg acttcgtttc cacccaactg taaaccaagg gatcttgaaa
      661 ttcctcggat ttgaacaaat ctttaaaaat gtcttaactg gacttcctat cggtggaggt
      721 aaaggtggat cagacttcga tcctaaaggt aaaacagatg ctgaagtgat gcgcttctgc
      781 caaagcttca tgactgaatt gcaaaaacac atcggaccat cacttgacgt acctgctggt
      841 gatatcggtg ttggtggacg tgagattggt tacctttacg gtcaatacaa acgtcttaac
      901 caatttgatg ctggtgtctt gactggtaaa cctcttggat ttggtggtag cttgattcgt
      961 ccagaagcaa ctggttacgg tttggtttac tatactgaag aaatgctcaa agctaacggt
     1021 aacagctttg ctggtaagaa agtcgttatt tcaggttctg gtaacgttgc tcaatatgct
     1081 cttcaaaaag caactgaact cggtgcaact gttatttctg tttctgactc aaatggttat
     1141 gtcatcgatg aaaatggtat cgacttcgat cttttggttg atgttaaaga aaaacgtcgt
     1201 gctcgtttga ctgagtatgc agctgaaaaa gcaactgcaa cctaccacga aggtactgta
     1261 tggacttacg ctggaaacta tgacattgct cttccatgtg ccactcaaaa cgaaatcaac
     1321 ggtgaagcag ctaaacgttt ggttgctcaa ggcgttatct gtgtatctga aggtgccaac
     1381 atgccgagcg accttgatgc catcaaagtt tacaaagaaa atggtatctt atacggacct
     1441 gcaaaagctg ccaacgctgg tggtgtagcc gtttcagctc ttgaaatgag ccaaaacagt
     1501 cttcgcctct catggactcg tgaagaagtt gatgaccgtc tcaaagacat catgacaaac
     1561 atcttcaaca cagctaaaac aacttcagaa acatacggtc ttgataaaga ctaccttgca
     1621 ggagctaaca ttgctgcctt tgaaaatgta gcaaatgcca tgattgcaca aggtattgtt
     1681 taagatttat ttactcaatc ctcaatcact acgattgggg attttta
//
LOCUS       DAVAGB010000104         1621 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVAGB010000104 DAVAGB010000000
VERSION     DAVAGB010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1621
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.106"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            <1..592
                     /locus_tag="VQO19_002126"
     CDS             <1..592
                     /locus_tag="VQO19_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET1350304.1"
                     /translation="AADFGIHESNLIRRSQWVEVTLVQSGVTISRTPLSSEDTVMIDA
                     TEVKINRPKKQLANDSGKKKFHVMKAQAIVTSQGRIVSLDITVNYCHDMKLFKMSRRN
                     IGQAGKILTDSGYQGLMKIYPQAQTPRKSSKLKPLTAEDKACNHALSKERSKVENIFA
                     KVETFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(1330..1590)
                     /locus_tag="VQO19_002127"
     CDS             complement(1330..1590)
                     /locus_tag="VQO19_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350305.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNNDISLDQNEIFEILKNFLDG"
BASE COUNT          541 a          303 c          292 g          485 t
ORIGIN      
        1 tgcggctgat tttggtattc acgaaagcaa cttaatccgt cggagccaat gggttgaagt
       61 aactcttgtt caaagtggtg ttacgatttc aagaactcct ctcagctctg aggacacggt
      121 aatgattgat gcgacggaag taaaaatcaa tcgccctaaa aaacaattag cgaatgattc
      181 tggtaaaaag aaatttcacg ttatgaaggc tcaagcgatt gtcacaagtc aagggagaat
      241 tgtttctttg gatatcactg tgaactattg tcatgatatg aagttgttca aaatgagtcg
      301 cagaaatatc ggacaagctg gtaaaatctt gactgacagt ggttatcaag ggctcatgaa
      361 gatatatcct caagcacaaa ctccacgtaa atccagcaaa ctcaagccgc taacagctga
      421 agataaagcc tgtaaccatg cgctatccaa ggagagaagc aaggttgaga acatctttgc
      481 caaagtagaa acgtttaaaa tgttttcaac aacctatcga aatcatcgta aacgctttgg
      541 attacgaatg aatttgattg ctggtattat caatcatgaa ctaggattct agttttgcag
      601 gaagtctatt atatatgcac agacatatga aatctttttg agacagcagt tatgatatat
      661 ttatccattc acaacatctt ctgtactaat actacaatat tggtacattt tgattacaca
      721 atcgtttcaa aaaatatgat ggaagcctga gtattttata gtaattccct tcctatcaac
      781 tagatcaacc agttgagtgt tgaatgttga aacaccctag cctcagcaaa ggactatgat
      841 cagcatttcc tagccaatag gacgctccaa atcacctatt ctaagtccat cactagcttg
      901 gtcagtaaga tacagactgc aaggcgagac tgatgtggtt gatgagattt tggaagagta
      961 ttacaatcat agattcacca gtagacttga ccgcagattt aactatagta gattgaaact
     1021 agaatagtac acctctactt ctaaaacatt gttagaaatc gatttgactg tcctgatcaa
     1081 tttgtcctgt tctcgtttca ttttactata ctaaaaaacc acctgaaaca aatcaagtga
     1141 ctagaggata aaaacaaaaa ctgggcaaaa agttttgaaa agcaaaaaac gcataatatc
     1201 aggtcttgaa aaaccttgat actatacgtt tgattgtggg aagattgact tcattttctc
     1261 ctgaaattga agttttttct agtttccaga tatagacgaa ttcaatatag ccatctcgct
     1321 acaattattt taaccatcga gaaaattttt cagaatttca aaaatttcat tttgatccaa
     1381 tgaaatgtca ttattttgaa gaatagttga cttcacaggc tctaattcta tcacaaagcg
     1441 gtgcatgtct gcttttaccg cactacttga tgttatagcc gataactttt catctcctag
     1501 caaggaagct gtcaaacggg taaggtcatt caaatgcttt ttaatggact tacttaaacc
     1561 ttgagcacct gtggcagagc gctccctcat atccagccaa gctttagcct taaaaataat
     1621 t
//
LOCUS       DAVAGB010000105         1539 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVAGB010000105 DAVAGB010000000
VERSION     DAVAGB010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1539
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.107"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            <1..>1539
                     /locus_tag="VQO19_002128"
     CDS             <1..>1539
                     /locus_tag="VQO19_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET1350306.1"
                     /translation="YVTSHGDHYHYYNGKVPYDAIISEELLMKDPNYQLKDSDIVNEI
                     KGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQEHSHNHGGGSNDQAVVAARAQG
                     RYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDLSASELAAAQAYWNGKQGSR
                     PSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSLLRELYAKPLSERHVESDGL
                     IFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIARIIPLRYRSNHWVPDSRPE
                     QPSPQSTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAK
                     DLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYDLLARIHQDLLDNKG
                     RQVDFEALDNLLERLKDVSSDKVKLVDDILAFLAPIRHPERLGKPNSQITYTDDEIQV
                     AKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKE
                     KGLTP"
BASE COUNT          489 a          332 c          320 g          398 t
ORIGIN      
        1 tatgtgacct ctcatggaga ccattatcat tactataatg gcaaggttcc ttatgatgcc
       61 atcatcagtg aagagctcct catgaaagat ccgaattatc agttgaagga ttcagacatt
      121 gtcaatgaaa tcaagggtgg ttatgtcatt aaggtaaacg gtaaatacta tgtttacctt
      181 aaggatgcag ctcatgcgga taatattcgg acaaaagaag agattaaacg tcagaagcag
      241 gaacacagtc ataatcacgg gggtggttct aacgatcaag cagtagttgc agccagagcc
      301 caaggacgct atacaacgga tgatggttat atcttcaatg catctgatat catcgaagat
      361 acgggcgatg cctatatcgt tcctcatggc aatcacttcc actatattcc taagagtgat
      421 ttatctgcca gtgaattagc tgctgcccaa gcctattgga atgggaagca gggatctcgt
      481 ccttcttcaa gttctagtca taatgcaaat ccagctcaac caagattgtc agagaaccac
      541 aatctgactg tcactccaac ttatcatcaa aatcaagggg aaaacatttc aagcctttta
      601 cgtgaattgt atgctaaacc cttatcagaa cgccatgtag aatctgatgg ccttattttc
      661 gacccagcgc aaatcacaag tcgaaccgcc agaggtgtag ctgtccctca tggtaaccat
      721 taccacttta tcccctatga acaaatgtct gaattggaaa aacgaattgc tcgtattatt
      781 ccccttcgtt atcgttcaaa ccattgggta ccagattcaa gaccagaaca accaagtcca
      841 caatcgactc cggaacctag tccaagtccg caacctgcac caaatcctca accagctcca
      901 agcaatccaa ttgatgagaa attggtcaaa gaagctgttc gaaaagtagg cgatggttat
      961 gtctttgagg agaatggagt ttctcgttat atcccagcca aggatctttc agcagaaaca
     1021 gcagcaggca ttgatagcaa actggccaag caggaaagtt tatctcataa gctaggagct
     1081 aagaaaactg acctcccatc tagtgatcga gaattttaca ataaggctta tgacttacta
     1141 gcaagaattc accaagattt acttgataat aaaggtcgac aagttgattt tgaggctttg
     1201 gataacctgt tggaacgact caaggatgtc tcaagtgata aagtcaagtt agtggatgat
     1261 attcttgcct tcttagctcc gattcgtcat ccagaacgtt taggaaaacc aaattcgcaa
     1321 attacctaca ctgatgatga gattcaagta gccaagttgg caggcaagta cacaacagaa
     1381 gacggttata tctttgatcc tcgtgatata accagtgatg agggggatgc ctatgtaact
     1441 ccacatatga cccatagcca ctggattaaa aaagatagtt tgtctgaagc tgagagagcg
     1501 gcagcccagg cttatgctaa agagaaaggt ttgacccct
//
LOCUS       DAVAGB010000106         1534 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVAGB010000106 DAVAGB010000000
VERSION     DAVAGB010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1534
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.108"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            76..965
                     /locus_tag="VQO19_002129"
                     /pseudo
     CDS             76..965
                     /locus_tag="VQO19_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(998..1338)
                     /gene="tnpB"
                     /locus_tag="VQO19_002130"
                     /pseudo
     CDS             complement(998..1338)
                     /gene="tnpB"
                     /locus_tag="VQO19_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
BASE COUNT          486 a          283 c          309 g          456 t
ORIGIN      
        1 ctctatcagg aaagtcaaat taatttatag aaatatttta gcagccaagg tgtactgtta
       61 tagattcaat atactataga ctgtaatcaa acaacgattt ggcgaaatgt aaaaaaatat
      121 gaggagttcg gactcgactc tctccttcaa gaaacacgtg gtggtcgtaa ccatgcatat
      181 atgacgattg agcaagagaa agcctttctt gcccgtcatt tgaagactac agatgcagga
      241 gaatttgtta caattgatgc cttatttcag gcttataaaa aggagttagg tcgttcctac
      301 acacgtgatg ccttctatca actgttgaag cgccatggtt ggcgaaatat tatgccacgt
      361 ccagaacatc ctaggaaagc agacgctcaa accattgtcg cgtctaaaaa taaaatctca
      421 attcaagaag aaaagaaagc gatttaaaac cagtagacgt tttcgtaagg ttcgcttgat
      481 gtaccaagat gaggctggtt tcggtagaat cagtaaactg ggatcttgtt gggctccaat
      541 aggagtaggt ccacatgtcc atagtcacta tatacgagaa tttcgctatt gttatgccta
      601 tacaggcgaa tcatttttct taatagctgg tggatgtaat actgagtgga tgaacgcctt
      661 tttagaagag ctttcacaag cttatccttt tactcgttat ggacaatgct atatggcata
      721 aatcaagtac cttaaagatt ccgactaata ttggctttgc atttattcct ccgtacacac
      781 cagagatgaa ccccattgaa caagtgtgga aagagattcg taaacgtgga tttaaaaata
      841 aagcctttca aactttggaa gatgtcatga atcaacttta agatatcata caaggactgg
      901 agaaggaggt gataaagccc atcgttaatc ggagatggac tagaatgctt tttgaaagca
      961 gatgagtata aaaagaaagt cctcatttca atagaaatca cgactttctg atggatttat
     1021 ttttggagtg atagaaaagc ccttcataag ccagtctact tgttcaggtg tgagagcttt
     1081 gacatccttt tctgtactgg gccaagtcag tctgccgttc tcaaagcgtt tatatagtag
     1141 ccaaaatcct tgaccatccc agtaaagggc tttaaagcgg tctttacgtc caccacaaaa
     1201 gagaaagact tgaccggaga aaggatccaa ttcaaagtgg gttttaacta cataggctaa
     1261 tgagtctatt ccctgcctca tatctatctt gctacaaaca aggtgaactt gacctaaatc
     1321 acttagttga attatcatag tacaatacct ttcctccgat aattattttt tatctagtat
     1381 actggaagtt ggggaattag gatagatacc ttgttatgac gcgcttacgt aacttgtaac
     1441 tagctgccta gtttgatctt tgcttcttca ttgattagca gtagatttca aaatgataaa
     1501 aacgtataat agtaggtgta gtgtactgcc cccc
//
LOCUS       DAVAGB010000107         1471 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVAGB010000107 DAVAGB010000000
VERSION     DAVAGB010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1471
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.109"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(<1..84)
                     /locus_tag="VQO19_002131"
     CDS             complement(<1..84)
                     /locus_tag="VQO19_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET1350307.1"
                     /translation="MKLSYEDKVQIYELRKQGYSLEKISNKF"
     gene            669..887
                     /locus_tag="VQO19_002132"
                     /pseudo
     CDS             669..887
                     /locus_tag="VQO19_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1187..1471)
                     /locus_tag="VQO19_002133"
                     /pseudo
     CDS             complement(1187..1471)
                     /locus_tag="VQO19_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          506 a          234 c          257 g          474 t
ORIGIN      
        1 aaatttattt gaaatcttct ctaagctata tccttgcttt cttagttcat agatctgaac
       61 tttatcctca taactcaatt tcataataaa acaccccaaa aagtagattt tttctgtcta
      121 acttttgggg tgcagttcat cttgtactgc ttttttcttt tacgacttac gctgtttggc
      181 ttcatgagca agccctcaaa gtgaactaat aacaaatcat gagaagtcaa agtgatgaaa
      241 tttctgtaac agaagtagag cgaattgctg aaccattaaa tgagtatatc tcgaagtaga
      301 agcgtctatt ttgactttta gtctgataga atggtagttt gaaaatgtaa atgatagcta
      361 ctgttcataa aacataaaag gtaagtacgg tgttgtgaga agagctagaa attagcactt
      421 acctgattat tccaataacc tcaaagatgt gataaaaatt tcaactactc ttatctataa
      481 taaagctacc tgttctttga aaattgaatt cactccgtct tgattagcgt gcctgtgtaa
      541 gtagggactg agagtatttc cctgtgaagg gcaactggca caagacgtgt gtgagaattt
      601 tctaacagac acggagttta tcgtttccag actcaaacga tgcgacaaac tagataaagg
      661 agttaatcat gaaggtagta aacttgtatg atttgaaaca aatgggaaat aaaggtggtt
      721 gtaccatcca attgattcat cactttcctt ttggtatggg cttaggacat ctcaaaaaag
      781 actacattga atttaaacgt gttggtatct ttgatgggaa agcagtagaa gttactcttc
      841 gagaacctta ttcgagagat ctacttcagg ttgtcaagtc aataaagtaa ctgacaccac
      901 gagtataatt attagaaacg tggaatctta ttaaatttta taataaatat attaaatgaa
      961 aaattattag atataaactt atgtaataaa acattgagga aataataaaa atctatgggt
     1021 aatgttctga aagtactttt aggttaggag agaaatataa tgatttttga aaattgattc
     1081 aaaaaatagc gaattgtaga aaacgcttaa caaatggtgt ataatagact tccagcgaaa
     1141 caaaatatgc tacaataaac ctatgaatta taaagcaacc ttatactcat ctgtcttcac
     1201 aaagcattct agtccatctc cgattaacga tggactttat catctccttc tccagtcctt
     1261 gtatgacatc ttccaaagtt cgaaaggctt tattcttaaa tccacgttta cgaatctctt
     1321 tccacactta ttcaatgggg ttcatctctg gtgtgtatgg aggaataaat gcaaagccaa
     1381 tattagtcgg aatctttaag gcacttgatt tatgccatat agcattgtcc ataacgagta
     1441 aaatataatc atctggataa gcttgtgaaa g
//
LOCUS       DAVAGB010000108         1348 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVAGB010000108 DAVAGB010000000
VERSION     DAVAGB010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1348
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.110"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            <1..113
                     /locus_tag="VQO19_002134"
     CDS             <1..113
                     /locus_tag="VQO19_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET1350308.1"
                     /translation="KVKTFKMFSTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            130..708
                     /locus_tag="VQO19_002135"
                     /pseudo
     CDS             130..708
                     /locus_tag="VQO19_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            721..891
                     /locus_tag="VQO19_002136"
     CDS             721..891
                     /locus_tag="VQO19_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350309.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
BASE COUNT          497 a          165 c          244 g          442 t
ORIGIN      
        1 ccaaagtaaa aacgtttaaa atgttttcaa caacctatcg aaatcatcgt aaacgttttg
       61 gattacgaat gaatttgagt gctggtatta tcaatcatga actaggattc tagttttgca
      121 ggaagtctat tatcaaaaat accatcagga ttatataaga ttgatacagg aaaagtttta
      181 tttgatggtg taaatattaa tcaaatagat aaaaaaatat taagtcaaaa tttaggagta
      241 gttccacagg attcgttttt attgaacaga agtattcttg ataacataac tttaaagcac
      301 gaagttactt cacaaaagat agaggaagtt tgtaaagcag ttcaaatcta tgatgaaatc
      361 atggctatgc cgatgaaatt taatactatc atctcagaga tgggttcaaa tatttcaggt
      421 ggtcaaagac aacggatagc actggcacgt gcattaataa ataatcctag tattgtaatt
      481 ttagatgaag caactagtgc tttagacact attaatgagg aaagaataac aaagtatata
      541 aaaagtcagg gctgtactca aataattgta gctcatagat tgtcaacgat taaggatgcg
      601 gatattattg ttgtaatgaa aggtggtaag attgttgagt caggaaatca taagtactta
      661 atggatcttg gtggagagta ctacagctta tatacaaaaa ggaaatgagg tgtaaagaaa
      721 atgaagaaag aaaatgaata tgtaatttta acaacagcct cactaggggt gatgattgga
      781 atagtgtttg caattttttt agattttcca gttgaatatg gtatttcttt aggcttattg
      841 aatggaatag tattgggttc gctgattgtt tacaaaaaca ataagaatta agcataattt
      901 tttgctgtaa actaaggagt agagatggct atagttgaaa ttataaatct aacaaaaagc
      961 tttaaagata ttgaagttat tcataacact taaataatag agcaactaca gtagtagctt
     1021 aaaaacatga ttaaatcgct attcttagga gtagcggttt ttctttttgt ttaatactct
     1081 ttgaaaatct cttcaaacca cgtcagcttt gccttgccgt actcaagtac agcctgcgac
     1141 tcgcttccta gtttgctttt tgattttcat tgagtataaa aagggttaag taagtatagt
     1201 aaattgaaat aagatatgaa caaatcgatt agaaaagtca aattaatttc tagaaatatg
     1261 ttagaaattg gtttgaattc cgcaatcaat ttgttcagtt tttatttcat ttaattagaa
     1321 tttcccaact gtctaactca actaaaaa
//
LOCUS       DAVAGB010000109         1278 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVAGB010000109 DAVAGB010000000
VERSION     DAVAGB010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1278
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.111"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(1..413)
                     /locus_tag="VQO19_002137"
                     /pseudo
     CDS             complement(1..413)
                     /locus_tag="VQO19_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(659..970)
                     /locus_tag="VQO19_002138"
     CDS             complement(659..970)
                     /locus_tag="VQO19_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350310.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(985..>1278)
                     /locus_tag="VQO19_002139"
     CDS             complement(985..>1278)
                     /locus_tag="VQO19_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HET1350311.1"
                     /translation="EVVSYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLH
                     DAKGNKIDRAPNPMELLTIKVPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
BASE COUNT          383 a          264 c          219 g          412 t
ORIGIN      
        1 attttacgac gagcaccaaa caactgctca ttttcagatg gtgtaccata gtaaaatcct
       61 gtagccagtt cacgttgggc aaccttccac atctcgtcca ccaagtcttg tttgatagct
      121 tcaaactttt caggactttc aagataggca tccacagccg ccttgtagca gttggttact
      181 gttaatacat agtgaataga ctccatacgt ccttcgattt ttagactgtc cacaccattt
      241 tcaatcatat ctggaatgtg gtcaatcata gacatgtcaa cggctgacat tgaaaattct
      301 tctggaatct caccctgcaa actcttacgt tctttcccaa atggcatatc gtaaaggtcg
      361 tacttccaac ggcatgactg agaacatcca ccacggttgg catcacgcat actctagacg
      421 gattgttttg acaattctaa tcttttagac tttgcataat aactgttaaa cagttgaaaa
      481 ttgacccagt tttaacaagt agtcaaaata ccagataaag gaaaaaagtc tttaaaatct
      541 taaaaacgca tagtatcagg tattgaacaa tcttgatatt atgcgtttta ttgtgggaag
      601 atttacttca ttttctcttg gaattgagtt ttctcctact tcaaaactag atgatttgct
      661 atttaaaata gcgttcctta tgattttggc aacctggatt aaagcgagaa aaacaaaagg
      721 ggcaacttaa gctttcttta tattgcttat atgttagtag ttttagacaa acaccacata
      781 aaataggctt atcctgtatc aaagataagg gatacggctc aaaagggtga ttttctaatg
      841 aatcatgaca ccgataacaa gcataatact ttttacaatc atagcattgt aaagcaataa
      901 tatccagctt gctatggtaa tgaatgcatc ttgtttgctt atccactaag aaaccctgtg
      961 cctctatcat ttccttttcc tttcttaagc tcgaactgtg acgctggttc catcttcctt
     1021 ataaagattg atgagtcctt cttttaatgc acgaaccatg tctcctgatt gaacgggttg
     1081 aggcacctta atagtcaata gttccattgg atttggagcg cggtcgattt tattgccttt
     1141 ggcatcatgc aaatcttcaa tataggtttc aaaatgacgg aaacctggac cataaaactc
     1201 aacttggtcc ccttcgttaa tgacatttcg ttgacgaata gttgctgttt gtgccgcatc
     1261 atcataagaa accacttc
//
LOCUS       DAVAGB010000110         1044 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVAGB010000110 DAVAGB010000000
VERSION     DAVAGB010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1044
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.112"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            <1..550
                     /locus_tag="VQO19_002140"
     CDS             <1..550
                     /locus_tag="VQO19_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET1350312.1"
                     /translation="ETSSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGTEIP
                     WVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPATH
                     NEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPISNH
                     EEMKRIISKVDLLFQKVSQLFE"
     gene            complement(498..1043)
                     /locus_tag="VQO19_002141"
     CDS             complement(498..1043)
                     /locus_tag="VQO19_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET1350313.1"
                     /translation="MNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT          373 a          168 c          150 g          353 t
ORIGIN      
        1 cgaaacatcc tcttatccta tatatgaaat cccagaagca tggagatata ttaaatttgc
       61 tagcctagtt aacttcagaa taggaaaaac tcctccacgc agtgaagcta ctttttgggg
      121 aactgaaata ccctgggtat ctatatcaga tatgcctata tctggttatg taactaatac
      181 gagagaatct atttctaaat tagcattaaa atcaaagaaa atagacattt cacctaaagg
      241 aactttatta atgagtttta aattatctat tggaaaagtt gccatattgg atattcctgc
      301 cactcataat gaagccatta tatcgatatt cccctatgct aataaagaaa atattatcag
      361 agattactta atgatatttt tgccacttat ctctacttta ggtgattcaa aagatgctat
      421 caaagggaaa acattaaata gtaccagtat ctccgaatta ttaatcccta tttctaatca
      481 tgaagagatg aaaagaatca tttccaaagt tgatttactt tttcaaaaag tttctcaact
      541 ttttgagtaa taagttcctg ttcctcaaaa ggagctaacg gaattaatag ctcgcttagt
      601 gtagttttag gaatattata taaagcttga cctgatagtt tagttattgc tttcaattgt
      661 ttataaaata acggagagga caagttaaat aatagaaatt ttgaaataat ctctgaactt
      721 tcgaatggtg ttaattggaa aataaatcca ccagccacaa caccatcata gtctttatcg
      781 attcttgcaa actttccaat atgttctaaa gaggttgata caggtgttat tagctgatta
      841 tgttttaaat aaacttgctc agaggagatg aattgtgtat caatgtagta atcattatcc
      901 aacagagaaa attctaaagg cttaatatta ccaccacgta taattctaac acctttatta
      961 ttaatgctta aatcgccctt cttgtaagaa agacctgtat tcattgaaaa aatatctttt
     1021 atttttataa caacccaatt cata
//
LOCUS       DAVAGB010000111         1017 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVAGB010000111 DAVAGB010000000
VERSION     DAVAGB010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1017
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.113"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(272..880)
                     /locus_tag="VQO19_002142"
     CDS             complement(272..880)
                     /locus_tag="VQO19_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HET1350314.1"
                     /translation="MQIKFIDKVSNLIMLNLLYVASVVTVIAIGSGESALIATLIKIV
                     RHEESYPYRDFANSFFKDYWKNLGAALISNLPILILLFSFFFLPYIPLPIYIISILRH
                     IGVIYIILHLMATTFLIPLIGRYNNTLKNSLHNSIMLAYKHFFIAVLIRIIEIIPVLL
                     FFILQNQLLVWITLMIFILPSITKYANAFLYNFIFSKYEKLN"
BASE COUNT          406 a           99 c          147 g          365 t
ORIGIN      
        1 aaactaaaag tatatttgat tttttgacaa tctaataaaa ttaagtaatt aaataacgca
       61 taagtcaagt attaaatacc atgatcttat gcgttttata ataaaaaatc tgttcttgtt
      121 ttatttttag aaaatttact aaagactaaa aatattgtga ataatttaaa aaatagtcag
      181 gttatatagt tttttgaaat taaaattatt ttatcgttga aattagttaa aaatttttat
      241 aaaatcaaga tgtaaggcta tgagatgttc tctagtttaa tttttcatac ttcgagaata
      301 taaagttata taaaaatgca ttagcatatt ttgttattga gggaagtata aaaatcatta
      361 aagttatcca aactagtaat tgattctgta atataaagaa gagtagaact gggataattt
      421 caataattct aataagaacg gcaataaaaa aatgtttata ggctaacatg attgaattgt
      481 gtagagaatt ttttaaagtg ttattatatc taccgattaa aggaattaga aatgttgttg
      541 ccattaaatg aagtatgata tatattactc caatgtgtcg taagatagaa atgatatata
      601 taggtaatgg tatgtagggt aggaagaaaa aactgaataa taagattaaa attggtaaat
      661 tagatattaa tgctgctcct aaatttttcc aataatcttt aaaaaaactg tttgcgaagt
      721 ctctataggg ataggattcc tcgtgtcgta caatttttat tagagttgct attagggcac
      781 tttcacctga tccgatagca ataactgtta ctactgacgc tacatagagt agatttaaca
      841 ttataagatt tgaaacttta tcaataaatt ttatctgcat ctttaactcc tgctgttttt
      901 atacttataa tatcacatca tttgagtttc atcaactttg aatacattaa gaaagaatat
      961 aactatgagg aaaggaaaaa attattatga ataaatccaa aaaatataaa gaaagaa
//
LOCUS       DAVAGB010000112         1014 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVAGB010000112 DAVAGB010000000
VERSION     DAVAGB010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1014
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.114"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(259..870)
                     /locus_tag="VQO19_002143"
     CDS             complement(259..870)
                     /locus_tag="VQO19_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET1350315.1"
                     /translation="MTKDILELESQKMSSDTFIDEIKNNYLSIVESTRKLIDGRQIEL
                     AIKLIREANQILIIGVGSSGNAAREFESSLLRIGIISKTVIDTHFQLMHTALLKDNDL
                     IIAFSLSGSTKEVEETLLNAKRKNVKIISITNYSSRNIAKLSDCVLLTSKKESYLEGG
                     SLMAKASQLFIIDVICTRLSLINYEDTICKKEEIASLLSNKVE"
     gene            complement(859..1014)
                     /locus_tag="VQO19_002144"
                     /pseudo
     CDS             complement(859..1014)
                     /locus_tag="VQO19_002144"
                     /inference="COORDINATES: protein motif:HMM:NF013577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
BASE COUNT          352 a          164 c          103 g          395 t
ORIGIN      
        1 aagaaaatca attttaggag aaaacaaggt taatagtcac atgatataat gcaatgatgt
       61 aaaaatcgaa caaattgatt ggaaaattca aactaatttc taacaatgat ttaagaattg
      121 ttatgtccta atatagattc aacgcactat aatcttaatt attgtttatt tttaaaactt
      181 tagcaaaaaa acgacccttt taggatcgtt ttttaattta ttttaaaaaa tttttattaa
      241 aatttaaaaa ttattgattt attccacttt atttgacagc aaagaagcaa tctcttcttt
      301 tttacatata gtatcttcat aatttattaa agagagtcta gtgcatatta catcaattat
      361 gaatagttga gaagccttag ccattaaact accaccctct aaataagatt ctttttttga
      421 tgtcaaaaga acgcagtcag ataattttgc tatatttctg gacgaataat ttgttattga
      481 aataatttta acattttttc tttttgcgtt taataaagtt tcctcaactt cttttgtgga
      541 accagataaa ctaaacgcta ttatcaaatc attatctttc aataacgcag tatgcatgag
      601 ttgaaaatgg gtatcaatta ccgtcttact tattattcca attcttaaca aactactctc
      661 aaattctcta gccgcatttc cactagaacc cacaccaata attaaaatct ggtttgcttc
      721 tcttattaat tttatagcta attctatttg tctaccatca attaattttc ttgtactttc
      781 cacaatagat aaataattat tttttatttc atcaataaat gtgtcactac tcattttttg
      841 agattctaac tctaatatat ctttcgtcat ttttaatttt agttcctgaa aaccagagta
      901 tccaatcttt ttgcaaaatc gattaagagt tccctctcca acttttactt tactaacaat
      961 ttctgaagac gtttcataaa ctatttcact atctctaact aaaatatagt cagc
//
LOCUS       DAVAGB010000113          863 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVAGB010000113 DAVAGB010000000
VERSION     DAVAGB010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..863
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.115"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(<1..>863)
                     /locus_tag="VQO19_002145"
     CDS             complement(<1..>863)
                     /locus_tag="VQO19_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET1350316.1"
                     /translation="SIQTETIDNKEIDILIIHDTDKVPVFLTKDYKPKKDTALPKGLI
                     YARNGSINTPKDSSAPFELINELFQKFNHTDLNIKEQYFHVLKDYKNWFFIENEDGRF
                     FIYNPNPDFYIKLNDDDANRFKTMSYSLNQYQTNIDWQLVQLRYRHLTIDECMAMYLD
                     QGNCLVPSPEVESFKIDYQETIYYHCLYKNTLKYQLLKVFSSIPGLEKYPLTRFKNSI
                     VIYDTKLELKKTHNLINSKFSSKDIVNQLEVTEKDFDFYYKKARHKNPDYSIQENQVN
                     LTELNLVRLLK"
BASE COUNT          282 a          113 c          126 g          342 t
ORIGIN      
        1 tttcaataac ctaactaagt ttaattcagt tagatttact tgattttctt ggatgctata
       61 atcaggattt ttatgtctag cttttttata gtaaaaatcg aaatcttttt ctgtaacttc
      121 aagttgattc actatgtctt ttgatgagaa tttactattt atcaagttgt gagtcttttt
      181 caattctaat tttgtgtcat aaattactat actattttta aatctagtta aaggatattt
      241 ttcgagacca ggtattgaag aaaatacttt cagcaattgg tactttaaag tatttttgta
      301 taagcagtga taataaatag tctcctgata atctatttta aaactttcta cttcagggga
      361 agggactaga caattacctt gatctaaata catagccata cactcgtcaa ttgtaagatg
      421 acgatatcga agttgtacta attgccaatc aatattagtc tggtattgat ttaaactata
      481 agacatagtt ttgaaacgat ttgcatcatc gtcgttaagt ttaatataaa aatcgggatt
      541 aggattataa ataaaaaatc ttccgtcttc attttcaatg aagaaccaat ttttatagtc
      601 ttttaaaaca tgaaaatact gctctttgat atttaagtcg gtatgattaa acttttgaaa
      661 caactcattt attaactcaa aaggagcaga ggagtcttta ggggtattta tagagccatt
      721 tctagcatat attaatcctt ttggtaatgc agtatctttc ttaggcttat aatcttttgt
      781 taaaaataca ggaactttat ctgtatcatg aataattaag atgtcaattt ctttgttgtc
      841 tatagtttca gtttgtatgc taa
//
LOCUS       DAVAGB010000114          838 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVAGB010000114 DAVAGB010000000
VERSION     DAVAGB010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..838
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.116"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            <1..>838
                     /locus_tag="VQO19_002146"
     CDS             <1..>838
                     /locus_tag="VQO19_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HET1350317.1"
                     /translation="DSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQLASQP
                     TLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEGVAYN
                     AHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFRMDSG
                     FATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSETLYQA
                     GSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIKEMKE
                     GFF"
BASE COUNT          227 a          195 c          168 g          248 t
ORIGIN      
        1 gattcagata tccttgtcca gttcctcttt caactgttaa caggctatgg aacggactat
       61 gcttgtaaag aattgtcagc tgatgcctac tttccaaaat tgttggaagg agggcagctt
      121 gcttcacagc caaccttatc ccgttttctt tccagaactg acgaggaaac agtccatagt
      181 ttgcgatgcc tcaaccttga attggtcgaa ttctttttac agtttcacca gctaaaccaa
      241 ctcattgtag atatcgattc tacccatttc acaacttatg gcaagcaaga aggtgttgct
      301 tataacgccc actatcgtgc tcatggctat catcctcttt atgctttcga ggggaagaca
      361 ggttattgtt tcaatgccca gcttcgtcct ggtaatcgtt attgttctga agaggcagac
      421 agctttatca cacctgtttt agaacggttt aatcaacttc tctttcgaat ggatagtggc
      481 tttgcgaccc caaaattata cgatttaatt gaaaaaacag ggcaatacta cctcataaaa
      541 ctcaagaaaa atactgttct gagccgtctt ggagaccttt ccctcccttg cccacaggat
      601 gaggacttaa ccatcttgcc ccactccgcc tactcagaaa ctctctatca agcaggatct
      661 tggtcgcaca agcgtcgtgt ctgccagttc tctgaacgaa aagaaggaaa cttgttctac
      721 gatgttattt ctctcgttac aaatatgacg agtggaacaa gccaagacca gtttcagctt
      781 tatcgtggac gtggtcaagc cgagaatttc atcaaggaga tgaaggaggg attttttg
//
LOCUS       DAVAGB010000115          798 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVAGB010000115 DAVAGB010000000
VERSION     DAVAGB010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..798
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.117"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            186..548
                     /locus_tag="VQO19_002147"
     CDS             186..548
                     /locus_tag="VQO19_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HET1350318.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
BASE COUNT          259 a          114 c          145 g          280 t
ORIGIN      
        1 aatctggaat agtccatcga gctttctaat actcttcgaa aatctcttca aaccacgtca
       61 acgtcgcctt gccgtgcgta tggttactga cttcgtcagt tctatccaca acctcaaaac
      121 agtgttttga gcaacctgag gctagtttcc tagtttgctc tttggttttc attgagtata
      181 acagattgtt agaagttggt ttaaatttcc taatcagttt gttcacattt accttcgata
      241 tattatatcc catagttaag gttggtcata cagatgatta tagtcatgga gccgtaaaac
      301 ttagtgtttc tttagttgac aaagatgcca tgaaaaaaat atctgtaact gtaataggat
      361 attttgaaat aaatatagat gaaaatatca ccgatattct atacgtaaat ggtactgcta
      421 ttctttatca ttatttacgt tctattgttt caatagtttc ggcaattgat agcagtgaag
      481 caatgttgct acctaccatt aatgttttag agttactaga taaatctcaa ccttttgaag
      541 aagaataatt tattagctca ctaaattgag ggtaaggaaa agtaaaatca gtaagaaaaa
      601 tgtcttgcat tatacagcaa ccttttggga atgagtagat ggattgaata aaatttgatt
      661 aagagtggat gatttatctg tagattatta ttggacagtt agtcttgaag tagtctaaga
      721 attaggttat aatcagtaga atccttgcta ataatgagga ggttagttta tgtatagtag
      781 actgaatcta aaatagta
//
LOCUS       DAVAGB010000116          661 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVAGB010000116 DAVAGB010000000
VERSION     DAVAGB010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..661
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.118"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(59..406)
                     /gene="ssrA"
                     /locus_tag="VQO19_002148"
     tmRNA           complement(59..406)
                     /gene="ssrA"
                     /locus_tag="VQO19_002148"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT          240 a          132 c          102 g          187 t
ORIGIN      
        1 aataaaaaac gttgatttaa caacgtttta ccaaggaatg caaaagaatg caaaggaata
       61 atggagccgg tgggagtcga acccacgtcc aaacacctgc caacatattt gtctacaacc
      121 ataggttatg tattatttta acagcccctc gacacataac tcaagtctag aaactgcgag
      181 tctatcaatc tcttatcaaa ccgctagaca aggcttaatc gtatctcgct aataataaga
      241 cctgtcattg aacacgagca atccaaatcg ggtcacgcct gctggttttt aggcagctag
      301 agcgtaagaa gtgttatttt ttgcagttat atttaactga gcgtttacgt cgccacacga
      361 gtcgcaaaat atgcctcata atgcctgtcg aatccgtaac gaccccaaaa gacaataaaa
      421 tcattatacc ttatctaact caaaaatgca aaaagaaatc acatacctaa gatgaagcta
      481 tctgttttga agaaattcac gaagagaatt attctaaaat actttcagat gagaattttc
      541 gtactctctt tatttcaatt catttgagtt taaaaactat aaaatcaatc cttatattat
      601 tcggactact tttcacttat tgcaccaaaa tatagtaaaa tgaaataaga atagaacgaa
      661 t
//
LOCUS       DAVAGB010000117          650 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVAGB010000117 DAVAGB010000000
VERSION     DAVAGB010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..650
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.119"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            complement(<1..>650)
                     /locus_tag="VQO19_002149"
     CDS             complement(<1..>650)
                     /locus_tag="VQO19_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET1350319.1"
                     /translation="TEIVQELMTEFSLVLLLKSIKLARSTYYYHLKQLDKTDKDQELK
                     AEIQSIFIEHKGNYAYRRIYLELRNRAYLVNHKRVQGLMKVLNLQAKMRQKRKYSSHK
                     GDVGKKAENLIQGQFEGSKTMEKCYTDVTEFAIPASTQKLYLSPVLDGFNSEIIAFNL
                     SCSPNLEQVQTMLEQAFTEKHYENTILHSDQGWQYQHDSYHQFLEGKGIQASMSRKG"
BASE COUNT          181 a          118 c          120 g          231 t
ORIGIN      
        1 cccttacgtg acatggatgc ttgaattccc ttaccctcaa gaaactgatg ataagaatcg
       61 tgttggtatt gccagccttg gtcactatgg agaatcgtat tctcgtagtg cttctctgtg
      121 aatgcctgtt ccaacattgt ttgtacttgt tctaaattag gcgaacaaga aagattaaaa
      181 gcaataattt cgctgttaaa gccatctaaa actggtgata agtaaagctt ttgagtactt
      241 gctggaatgg caaattctgt cacatctgta tagcactttt ccattgtttt agagccttca
      301 aattggcctt gaatgagatt ctctgccttc ttgccaacgt ctcctttatg agaagaatat
      361 tttcgtttct gtcgcatttt agcttgtaaa ttgagtactt tcatcaagcc ttgaactctt
      421 ttatgattta ccagataagc acgatttctt agttctaaat aaatccgacg ataagcataa
      481 tttcccttgt gttcgataaa aatggattga atttcagctt taagctcttg gtccttatct
      541 gttttgtcta gctgtttcaa gtgatagtag taggtcgaac gagctagttt aatggatttt
      601 agaagaagaa ctaacgaaaa ctcagtcatt aattcttgaa caatttctgt
//
LOCUS       DAVAGB010000118          640 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVAGB010000118 DAVAGB010000000
VERSION     DAVAGB010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..640
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.120"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            <1..>640
                     /locus_tag="VQO19_002150"
     CDS             <1..>640
                     /locus_tag="VQO19_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002644521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350320.1"
                     /translation="LNQKLSQAEFEVRAGSIRQEILNATKDKASKSELTQTAEELASR
                     IASVQASGRNLFLNSLFKQDIPKTGIWTTSTYTATIDSESKYLGHKALKIIGLNPSGR
                     DGGNPKVTYPALGQFGKVIPGSTTNQDVTISFYAKANKNGIMLRSRLGNIGYKTGNVT
                     LSTEIKRYVVHIPKGWTNESKQTTNEWLFNFNQEGTVWIWMPKFEISDVDTSY"
BASE COUNT          214 a          114 c          149 g          163 t
ORIGIN      
        1 ctaaatcaga agttgagtca ggctgaattt gaggtgcgag ctggctctat ccgtcaggaa
       61 atcctgaatg caaccaagga taaagccagc aagtcagaac tcacgcagac agctgaggag
      121 ctggctagtc ggattgcgag tgtgcaggca tccggtcgaa atctattctt gaactcacta
      181 ttcaagcagg atattccaaa aacaggaatt tggacaacga gtacatatac ggctactatc
      241 gatagcgaaa gtaagtatct tggacacaag gctcttaaaa ttataggtct gaatccatct
      301 ggtcgtgatg gagggaatcc caaggttact tatccagctc tgggtcaatt cgggaaagta
      361 attcccggaa gtacgactaa tcaagatgta accattagtt tttatgctaa ggcaaataaa
      421 aatggaataa tgctaagatc tcgattaggg aatatcggat ataaaactgg aaatgtgaca
      481 ttgtcgacag aaattaaacg atatgttgtc catattccaa aaggttggac aaacgaatcc
      541 aagcagacca caaatgaatg gttgttcaat ttcaaccagg aaggaactgt ttggatttgg
      601 atgccgaagt ttgaaataag cgatgtagat acttcttatt
//
LOCUS       DAVAGB010000119          622 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVAGB010000119 DAVAGB010000000
VERSION     DAVAGB010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..622
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.121"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            105..584
                     /locus_tag="VQO19_002151"
     CDS             105..584
                     /locus_tag="VQO19_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET1350321.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          233 a           82 c          142 g          165 t
ORIGIN      
        1 ccctctcttt tttgtgcagt ttaggagcta aagggaacag aatggagaaa atggaacaaa
       61 tgtgttttct aatctgttag actgtatcta gaaaggggaa aattatgatt aaagaattgt
      121 atgaagaagt ccaagggact gtttataagt gtagaaatga atattacctt catttatggg
      181 aattgtcgga ttgggaccaa gaaggcatgc tctgcttaca tgaattgatt agtagagaag
      241 aaggactggt agacgatatt ccacgtttaa ggaaatattt caaaaccaag tttcgaaatc
      301 gaattttaga ctatatccgt aagcaggaaa gtcagaagcg tagatacgat aaagaaccct
      361 atgaagaagt gggtgagatc agtcatcgta taagtgaggg gggtctctgg ctagatgatt
      421 attatctctt tcatgaaaca ctaagagatt atagaaacaa acaaagtaaa gagaaacaag
      481 aagaactaga acgcgtctta agcaatgaac gatttcgagg gcgtcaaaga gtattaagag
      541 acttacgcat tgtgtttaag gagtttacta tccgtaccca ctagtaagtc atgcaaaaaa
      601 aatgaaaaaa attagaaaaa gt
//
LOCUS       DAVAGB010000120          583 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVAGB010000120 DAVAGB010000000
VERSION     DAVAGB010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..583
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.122"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            <1..>583
                     /locus_tag="VQO19_002152"
     CDS             <1..>583
                     /locus_tag="VQO19_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET1350322.1"
                     /translation="DLARQLFPCAKIVLDRFHIVQHLSRAMSRVRVQIMNQLDRKSHE
                     YKAIKRYWKLIQQDSRKLSDKHFYRPTFRMHLTNKEILNKLLSYSQDLKHHYQLYQLL
                     LFHFQNKEPEKFFGLIEDNLKQVHPLFQTVFKTFLKDKEKIVNALQLHYSNAKLEATN
                     NLIKLIKRNAFGFRNFENFKKRIFIALNIKKERT"
BASE COUNT          192 a          127 c           95 g          169 t
ORIGIN      
        1 atgacttagc tagacaactt ttcccatgtg ctaaaatcgt gttggatcgc tttcacattg
       61 tacaacatct tagccgtgct atgagtcgtg tgcgtgttca aatcatgaat caattggatc
      121 gaaagtctca tgaatacaag gctatcaagc gctactggaa gctcatacaa caggatagtc
      181 gtaaactcag cgataaacat ttttatcgcc ctacttttcg tatgcattta accaataaag
      241 agattttaaa caagcttttg agctattcac aagacttgaa acaccactat cagctctatc
      301 aactcttgct gtttcacttt cagaataagg aaccggagaa atttttcgga ctcattgagg
      361 acaatctaaa gcaggttcat cctctttttc agactgtctt taaaaccttt ctaaaggaca
      421 aagagaaaat cgtcaacgcc cttcaactac actattctaa cgccaaattg gaagcgacca
      481 ataatctcat caaacttatc aagcgcaatg cctttggttt tcggaacttt gaaaacttca
      541 aaaaacggat ttttatcgcc ctgaatatca aaaaagaaag gac
//
LOCUS       DAVAGB010000121          502 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVAGB010000121 DAVAGB010000000
VERSION     DAVAGB010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..502
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.123"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            1..502
                     /locus_tag="VQO19_002153"
                     /pseudo
     CDS             1..502
                     /locus_tag="VQO19_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          150 a          114 c           85 g          153 t
ORIGIN      
        1 tattgcgcaa gattttaaca atctcaatat catcactgtt cttgaaggca gaacacaagc
       61 tgtcatccga gatcactttc ttaaatatga tagagccgtc cgatgtcgcg tcaaaatcat
      121 tactatggat atgtttagtc cttactatga cttggctaaa cagcttcgct ttcaaatttc
      181 taggctcagg ctgaaacagt ctcccagact gtttcactcc cgaatgctaa aatcgttctt
      241 gatcgctttc acattgtaca acatcttagc cgtgctatga gtcgtgtgcg tgttcaaatc
      301 atgaatcagt ttcatcaaaa atcccatgaa tacaaggcta tcaagcgcta ctggaagctc
      361 atacaacagg atagccgtaa actgagtgat aagcgatttt atcgtcctac ttttcgtatg
      421 catttaacca ataaagagat tttagacaag cttttgagct attcacaaga cttgaaacac
      481 cactatcagc tctatcagct ct
//
LOCUS       DAVAGB010000122          485 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVAGB010000122 DAVAGB010000000
VERSION     DAVAGB010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.124"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            1..485
                     /locus_tag="VQO19_002154"
                     /pseudo
     CDS             1..485
                     /locus_tag="VQO19_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          177 a           88 c           89 g          131 t
ORIGIN      
        1 tcttcttcta aaagccatta aactagctcg ttcgacctac tactatcact tgaaacagct
       61 agataaacca gataaggacc aagagcttaa agctgaaatt caatccatct ttatcgaaca
      121 caagggaaat tatggttatc gtcggattta tttagaacta agaaatcgtg gttatctggt
      181 aaatcataaa agagttcaag gcttgatgaa ggtactcaat ttacaagcta aaatgcgaca
      241 gaaacgaaaa taaaggagac gttggtaaga aggcagagaa tctcattcaa ggccaatttg
      301 aaggctctaa aacaatggaa aagtgctaca cagatgtgac agaatttgcc attccagcaa
      361 gtactcaaaa gctttactta tcaccagttt tagacggctt taacagcgaa attattgctt
      421 ttaatctttc ttgttcgcct aatttagaac aagtacaaac aatgttggaa caggcattca
      481 cagag
//
LOCUS       DAVAGB010000123          422 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVAGB010000123 DAVAGB010000000
VERSION     DAVAGB010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.125"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            <1..>422
                     /locus_tag="VQO19_002155"
     CDS             <1..>422
                     /locus_tag="VQO19_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HET1350323.1"
                     /translation="EARFDKLIEIKRLTASKIQDILSVAPRSIGTTSPAREFEIIEII
                     KHYKRLIDKAETCVNDLMAEFNSVITTVTGIGGRLGAVILAEIRNIHAFDNPAQLQAF
                     AGLDSSIYQSGQIDLAGRMIKRGSPHLRWALIQAAKAC"
BASE COUNT          115 a           91 c           97 g          119 t
ORIGIN      
        1 ttgaggcaag atttgataag ctgatagaaa ttaagcgatt gaccgcttct aaaattcagg
       61 atatcctctc agtcgcacct cgttctatcg gaacaacatc tcctgctcgt gaattcgaaa
      121 tcatcgaaat catcaaacat tacaagaggc tcattgacaa ggcggaaaca tgtgtcaatg
      181 acttgatggc tgagttcaac tcggtcatca cgacggttac tgggattggg ggtcgtttag
      241 gggcggtcat tttagccgag attcgaaata ttcatgcctt tgataatcct gctcaattac
      301 aagctttcgc tggactggat tcttctattt atcagtcagg tcagattgat ttagctggaa
      361 gaatgatcaa acggggttcc cctcatctgc ggtgggcact catacaagct gccaaagcat
      421 gc
//
LOCUS       DAVAGB010000124          340 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVAGB010000124 DAVAGB010000000
VERSION     DAVAGB010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..340
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.126"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            1..340
                     /locus_tag="VQO19_002156"
                     /pseudo
     CDS             1..340
                     /locus_tag="VQO19_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          101 a           76 c           59 g          104 t
ORIGIN      
        1 attactatgg atatgtttag cccttactat gacttggcta aacagcttcg ctttcaaatt
       61 tctaggctca ggctgaaaca gtctcctaga ctgtttcact cccgaatgct aaaatcgttc
      121 ttgatcgctt tcacattgta caacatctta gccgtgctat gagtcgtgtg cgtgtccaaa
      181 tcatgaatca gtttcatcga aaatcccatg aacacaaggc tatcaagcac tactggaagc
      241 tcatacaaca ggatagccgt aaactgagtg ataagcaatt ttatcgtcct acttttcgta
      301 tgcacttaac caataaagag attttaaaca agcttttgag
//
LOCUS       DAVAGB010000125          284 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVAGB010000125 DAVAGB010000000
VERSION     DAVAGB010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.127"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            <1..>284
                     /locus_tag="VQO19_002157"
     CDS             <1..>284
                     /locus_tag="VQO19_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET1350324.1"
                     /translation="TPTYREALITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAE
                     KVVVVRLEKPVTFHNMIAPDKEVEVSLLFFIINNSSSSQTNILAQLMDFFT"
BASE COUNT           89 a           53 c           52 g           90 t
ORIGIN      
        1 actccaactt atcgtgaagc cttgatcacg cgtgaaaagt catttccaac tggtttagat
       61 atggaatttc taggaaagga cttgccaaat gtagcgattc ctcatacaga tattgttcat
      121 aatctagctg agaaagtggt ggttgttcga ttagaaaaac cagtaacttt tcacaatatg
      181 atagctcctg ataaggaagt agaagtatcc ttgctcttct ttatcatcaa taactcaagt
      241 tcaagtcaaa caaatattct ggctcagttg atggactttt tcac
//
LOCUS       DAVAGB010000126          275 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVAGB010000126 DAVAGB010000000
VERSION     DAVAGB010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.128"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
BASE COUNT           93 a           47 c           67 g           68 t
ORIGIN      
        1 tccgaattgt tttcagcact ttattctagg attagaaaag tcaacctgaa tcttcctgtt
       61 ccttatgaac cacctagaag aaaagcgtcg ttaatgatgc attaaagaac agtcgagatg
      121 aaaaaatcgt gtgacgcacc aagggaggag tctgcccttt tgaggaaatc tagcgaggaa
      181 aaacgatact ggaacagcag aaagtaaaac tgacctcatg aggaggaaga aagtggctca
      241 tgaggtcagg ggttttgtaa gttacatcta gttga
//
LOCUS       DAVAGB010000127          269 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVAGB010000127 DAVAGB010000000
VERSION     DAVAGB010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..269
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.129"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
BASE COUNT          104 a           43 c           30 g           92 t
ORIGIN      
        1 tgatagaact gttcatatct tatttcaatt ctctatatta tacgttgaac caaacccttc
       61 tattgctttc ttaaaaattt ataagagtta taaaatctgt taaatttcaa tgtgtatatc
      121 taaactacgg tatttattga aaagactgga gacaaaaagt atacgctgcc aaaatgaatt
      181 actgaaaatc aaaaaagaga gaaccaaact gattccctct taatgtatat aatatctagt
      241 tttaaaaata cacactcaca tatctctgt
//
LOCUS       DAVAGB010000128          262 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVAGB010000128 DAVAGB010000000
VERSION     DAVAGB010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..262
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.130"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
BASE COUNT           88 a           45 c           54 g           75 t
ORIGIN      
        1 ctgttctaat actcaatgaa aatcaaagag taaactagga agctggccgc aggttgctca
       61 aaacacagtt ttgaggttgt agataagact gacgaagtca gtgatcatat cgtaaccgtc
      121 caatagactt cgttattggg cggttacgaa aaacttcctt ccaaataaaa aggggctcta
      181 taatatttgt agtgggtaaa tcccctatgg atattatgga gcctattttt gtgtagaaaa
      241 aaagtcccat atgacctata at
//
LOCUS       DAVAGB010000129          227 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVAGB010000129 DAVAGB010000000
VERSION     DAVAGB010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 227)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 227)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..227
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.denovo.131"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            <1..>227
                     /locus_tag="VQO19_002158"
     CDS             <1..>227
                     /locus_tag="VQO19_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350325.1"
                     /translation="TVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLAT
                     VKYYVEHPNERPHSDNGFGNASDHVQRNKNG"
BASE COUNT           74 a           44 c           47 g           62 t
ORIGIN      
        1 actgtagaag tcaaaaacgg tagtttaatc atacctcatt atgaccatta ccataacatc
       61 aaatttgagt ggtttgacga aggcctttat gaggcaccta aggggtatac tcttgaggat
      121 cttttggcga ctgtcaagta ctatgtcgaa catccaaacg aacgtccgca ttcagataat
      181 ggttttggta acgctagcga ccatgttcaa agaaacaaaa atggtca
//
LOCUS       DAVAGB010000130        13493 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.guided.048, whole genome shotgun sequence.
ACCESSION   DAVAGB010000130 DAVAGB010000000
VERSION     DAVAGB010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13493
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.guided.048"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            22..324
                     /locus_tag="VQO19_002159"
     CDS             22..324
                     /locus_tag="VQO19_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET1350326.1"
                     /translation="MDDKNYRVFENFISVSFLGAVFYHKYKASLDMKIHCLKLKNKEL
                     NKEVAFYLTSIIRQALKNTEYKDQISSTVLPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            290..603
                     /locus_tag="VQO19_002160"
                     /pseudo
     CDS             290..603
                     /locus_tag="VQO19_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1287..1448
                     /locus_tag="VQO19_002161"
     CDS             1287..1448
                     /locus_tag="VQO19_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350327.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            1540..3219
                     /locus_tag="VQO19_002162"
     CDS             1540..3219
                     /locus_tag="VQO19_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HET1350328.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEDCIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIDLDNDEQVECVSLLEKRS"
     gene            3487..4053
                     /locus_tag="VQO19_002163"
     CDS             3487..4053
                     /locus_tag="VQO19_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350329.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            4375..4563
                     /locus_tag="VQO19_002164"
     CDS             4375..4563
                     /locus_tag="VQO19_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HET1350330.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            4625..5383
                     /locus_tag="VQO19_002165"
     CDS             4625..5383
                     /locus_tag="VQO19_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET1350331.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEAVLYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            5441..5902
                     /locus_tag="VQO19_002166"
     CDS             5441..5902
                     /locus_tag="VQO19_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HET1350332.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRF"
     gene            5936..6295
                     /locus_tag="VQO19_002167"
     CDS             5936..6295
                     /locus_tag="VQO19_002167"
                     /inference="COORDINATES: protein motif:HMM:NF015692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HET1350333.1"
                     /translation="MNDNPIECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQET
                     VPQAIIAFLESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLD
                     EPLKDVVRRWENRIKVY"
     gene            6407..7315
                     /locus_tag="VQO19_002168"
     CDS             6407..7315
                     /locus_tag="VQO19_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HET1350334.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKQGILA
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVIANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKVEVFSKPKED"
     gene            7478..9217
                     /locus_tag="VQO19_002169"
     CDS             7478..9217
                     /locus_tag="VQO19_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HET1350335.1"
                     /translation="MELSAIYHRTESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELE
                     NQLVISPDGFVIF"
     gene            9492..9794
                     /locus_tag="VQO19_002170"
     CDS             9492..9794
                     /locus_tag="VQO19_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350336.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKLVSINE"
     gene            9850..10278
                     /locus_tag="VQO19_002171"
     CDS             9850..10278
                     /locus_tag="VQO19_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET1350337.1"
                     /translation="MDGITKDFIKTAKLMKQLWPQLTDKEAIDEVKKYTNGKNTAIFT
                     EVEGDTIVGLALCSLRFDYVEGCKYSPVGFLEGIIVDEEYRLKDIAKNLCTKCEEWAK
                     NKGCKEFASDCTLTNTDSIRFHLNIGFQEANRIIHFKKKL"
     gene            10336..10945
                     /locus_tag="VQO19_002172"
                     /pseudo
     CDS             10336..10945
                     /locus_tag="VQO19_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000662948.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
     gene            11227..11474
                     /locus_tag="VQO19_002173"
                     /pseudo
     CDS             11227..11474
                     /locus_tag="VQO19_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335280.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
     gene            11579..11881
                     /locus_tag="VQO19_002174"
                     /pseudo
     CDS             11579..11881
                     /locus_tag="VQO19_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            12037..13266
                     /locus_tag="VQO19_002175"
     CDS             12037..13266
                     /locus_tag="VQO19_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET1350338.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            13286..>13493
                     /locus_tag="VQO19_002176"
     CDS             13286..>13493
                     /locus_tag="VQO19_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HET1350339.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEM"
BASE COUNT         4741 a         1886 c         2785 g         4081 t
ORIGIN      
        1 atcttaggtt actacgaaga tatagatgat aaaaattata gagtttttga aaattttata
       61 tctgtttcat ttttaggagc agtcttttat cataaatata aagcaagcct agatatgaaa
      121 attcattgtt taaaattaaa aaataaagaa ttgaataaag aagtagcatt ctatttaact
      181 tcaattatta ggcaagcttt aaaaaatact gaatataaag atcaaatatc tagcacagta
      241 ttgccagata tcaaaattaa attaccgata gacagtagag gtactccaga ttggaattac
      301 atggaaagat atagagatag ataaagagag agggagagat agataaaaag tccaccccca
      361 tttttttatg gagaattcaa aaatgtaagg ttaagcaaag aagaatataa aaatctaaaa
      421 gaaaaattaa actcacacac agatataatg ataaataaac tatccagata catggaaagc
      481 agtggtaaga cctatcaaaa ccactatgtg acaatcttaa aatggtatga agaagataaa
      541 gacaaactaa gacagaaagg tttaaataaa aaaatgaatt atgatgtagg agaatcttta
      601 tagataaaaa gaggtggaaa ggcactatta aagactttaa gtctaaaaag gtatcaaagt
      661 atgccagaga taaaaaaata taaatatgac actttaaagg tgattagaaa attaaagaaa
      721 tgctagaaga cttttagatg acagttacca agagggtcta attttcactg ctacttatgc
      781 agtgggaatt ggaccttttt atataagcaa attctatttc aaaattggtt accaagaaag
      841 acttcttttc actgttaagt ataagagggt aatttataga attttgttac attaagataa
      901 atattttctg atggtcaaat tttaaaaaga ttaataattc tcgataaatt ttgaacctta
      961 acaattgaat agaccaagac aagacgttaa ttatttttgg agcgtaataa cctatccgtc
     1021 aagatctttc ggctgaataa ttcggcaaaa aaagttctgc taagtaaaaa gaaagtgagc
     1081 gataagtaag agtttgaata tagggaggga taccctatcc gctatgaaga aaatgaggat
     1141 aatgatactt ctaaggttga agccggctca tccggaatag aggcggaggt gagattccta
     1201 tgttgctaat ccaaagcact tgtcaatgtc aaaaaactta attaaacaaa taattattag
     1261 atataaaact ttagaggagg tatatattgg acaatgactg gaatggattg gctgatttaa
     1321 tagcaaatct gattgcaaaa tatgctggtg ctttagattt agataatcta cccgatccaa
     1381 cgccagcaaa aaatcaagag atgaaaaata gttttgacat ggcaaaaaca caaattgaga
     1441 cggactaata aaagtgttat aatatacttg aaatgatagt ccaaacttaa attaaaaaaa
     1501 ttatatatga tatagaaaaa ttatattgag gttaatacta tgtcaaaaga aaaaataaaa
     1561 gtatacctct atacacgagt atctacgtca atacagatag aggggtattc gttagaggca
     1621 caaaaatcac gaatgaaagc ttttgctatt tacaacgatt atgaaattgt tggagagtat
     1681 gaagatgccg ggaagtctgg caagtctatt gaaggtagaa tacagttcaa tcgaatgatg
     1741 gaagatataa aatctggaaa agatggagta tcttttgttc ttgtgtttaa gttatcaaga
     1801 tttgcaagaa atgccgctga tgttctttct acacttcaga taatgcagga ttatggagtt
     1861 aatcttatct gcgttgaaga tggcattgat tcatctaaag atgctgggaa actaatgatt
     1921 tctgttttat cagctgtggc tgaaatagaa agagaaaaca tccgtattca aacaatggaa
     1981 gattgcattc aaaaagcaag ggaaggaaaa tggaatggtg gctttgctcc gtatggatat
     2041 aaacttgaag acggcaagct gtttataaat gaggaagagg cagttgcaat aagaacgatt
     2101 ttcgaccagt atgtaaatac tacgatagga gccaatggga tatctaaata cttagagaat
     2161 catggaatta gaaaaatccc aagacagaat ggtaagaatc ctttgtttga tgcaggtctt
     2221 ataagaaaga tattaaagaa tcctgtatat aatgggaaaa tagcatttgg aagaagaact
     2281 ttagaaaaag ttcatggtac aagaaatgaa tataagcagg ttgaacaaga tgaatatcta
     2341 atatctgaag ggatacatga agctatagtt tccgatgaag tttggcaagc tgctcaggtt
     2401 aagctaaaat ctcaagcaaa gaaatatgag catgtgaata aaggaaaaga tacacgcaca
     2461 cacttgcttt ctggaattgt aaaatgcccg atatgtggag tgggaatgtt tgggaacaag
     2521 tgtatcaaga aaaagaaaga tggcacaaag tataaagatt tttattacta tggttgtaaa
     2581 cataggcaga tgataagagg tcataagtgt acattcagta agcaaattag agaagaattg
     2641 ttagatgatg ctgttgcaga ggtgattgtc aagatagtaa gtaatccgaa atttgcttct
     2701 atgatgcaag aaaaaatcaa catgaaggtg gatacctctg aaatagaaaa agaaatagat
     2761 aattaccaaa aggaattgag aaagagtcat tctacaaagt ttaagctaat tgaggaaata
     2821 gataatttag atgttgaaga taagcactat aagagaagga aacaggattt agatgataga
     2881 ctatatcgta tgtatgacaa aatagatgaa ttagaatcat cactaattga tgcgaaagca
     2941 aagaaacaga ctattgaagc tgaaaaactt acaggagata acatatataa ggttctgatc
     3001 tattttgata agctctataa agtcatgaat gatgtagagc gtaggcagtt aatttcagct
     3061 ttgatttctg aaattcaagt ttatgaagaa aaacaatcta acggacaatg gctaaaatcc
     3121 attactttta agctaccaat tatagaagaa aatctcaaca tagatttgga caatgatgaa
     3181 caagttgaat gtgtaagttt attagagaaa cgtagttaat cctcaaaagg ttccccaaac
     3241 tttttgagtc ccactgacgc atcacgctga ggcggtatca ctgcttgtac gagttgaagc
     3301 atcagcgaag taaaagtaga tgttcagcca atgcgacgag gtgagaccga aggtcgataa
     3361 ggtgtgttct gggtatagga ctcgtaaagt aagtaggaaa tatgatgaga tgatacagag
     3421 agcctgaatt ggtcaggtga cgtgcttatt tacattagcc tgataatgaa aatggagaga
     3481 ttatcgatgg ttatattgga attgtaccaa aatgattatt ctaaagattt agtagcattt
     3541 gattccatag aagatgggaa agcctttgtg gctcaaatcc cgggatacac tctggaaaca
     3601 gaagatggtt ttgaagtgga gtattttaat cctaaaaaca taccggatta tatggaaatt
     3661 atttttaacg gaaatattgt tcctttatct aaatttatgt tcgatcctga ggaaaatgta
     3721 aacattattt ggaaagagat ttcaaattta tccctcaaaa atgatagagt gatcgaagga
     3781 tattcaaaaa ttgatgcata tgtcgttaac aaccatgaag ttaaagccta tgtcgaaaca
     3841 agagaaacga actatcgtaa agcaaaagac ttcttagaaa gccgcggata tgaaatcgac
     3901 agaagctttt tcggaagtga agacggtgaa gcgattcttt acagaaaaaa agggatcgaa
     3961 gtttggcatt tcttgtgtca cttagaccca atgtttgtag agattgaaga tgtagaagga
     4021 tatgttaaag aagaagttgg agagattcaa tagtcaacca aagttccttg tgagtatata
     4081 cctttgctag taaaagagtc aaaacgttat aacgaagggg gggaagaaaa cccttgagtg
     4141 taagtctttt tcttgtttag agggaaagta ttagagtagc cgctcataat ttatactaga
     4201 tttgataact gatttgagac agattttatt tctataaata ttgtgaaaat tttttaatac
     4261 caaagattta aagttactgt gttaaaaatc ctctccactt ttaaactaat gtattataaa
     4321 agccagttga cacaagtgtt acacctgtga tagaattaac ttgaggtgat gaaaatggca
     4381 accgataaaa atagaataat gattagcttg gatgataaaa atctagagaa acttgaaaat
     4441 ttagtagaag atgctagaga tagaagggga atgcgactaa caaagtccca ggttattgaa
     4501 ttactcctaa ataccgttga ttatttcgat gatattatgg gggctattta ctcaaaaaaa
     4561 taagagcaaa attgctatta ttttttacaa attggtgtaa cactagtgat ataggagtga
     4621 tgaaatggtt gtttatatta gacaaagtaa attaccaagt gaggtttcaa ttaataaata
     4681 caatgctcaa gtaggtgcct acttacaagg agaagaagct gttttatatc aatctttttc
     4741 tgaaataaaa gagttaacaa gtgaagatat agttgtagat tatataatgg agactagagc
     4801 attactaaaa atgatgggct taaacgttcc ggttcatgac tatcctattg agcttaaaga
     4861 gttttatggt cgaaagattt atgctggtat tttaggagag attgtgaata tacctgataa
     4921 ttggggaaaa tttattaagc ctaaagctgg ttcaaaagtc tttactggaa gagttgttaa
     4981 tggaacccat gatttaatag gtattggtct acctttcgac tatcctatat ggattagtga
     5041 ggttgtagaa ttcatagctg aatggcgttg ttttgtgtta gatggtcgcg tattagatgt
     5101 tcgaccctat acaggtgatt atcatgcaca atttgatgca agtgtaattg atgaagcgat
     5161 atcatgttgg aaagatgcgc caatagctta tggactagat atcggtgtta ctcgcgatgg
     5221 cagaacactt gttgttgaag taaatgatgg ttatgcattg ggaaattatg gcctatctcc
     5281 tttaaaatca atcaattttc atagagctag gtggaaagaa atggtaaaac cctattttga
     5341 aaaaaatgaa atttttaaaa tccaacagga tgttgttttc taaaataaat atggtatata
     5401 accaatataa aaagcatcaa aatgaacaag gaggaatctg atgcttggag caattattgg
     5461 agatattgtc ggttctgttt acgaatggaa caatatcaaa acaaaggact ttcctttatt
     5521 tcggaaggac tgctttttta cagatgacac ggttatgacc tgtgctgttg cagaagcaat
     5581 tatgaatggt ggacaaaaag acgacttcat tgacgcgatg aagaaatatg gcagaatgta
     5641 tccgaatgct gattacggtg ctcggtttaa tgcatggcta aacagcgata accgtgagcc
     5701 ttataatagc tttgggaatg gatcagctat gcgtatttct ccatgtgctt ggatcatgga
     5761 ctgtggtttt tatgcgaaaa ctggtatatg gccatcatct agaggactta cgagtctttc
     5821 tgcagaggta actcataatc atccagaagg tgtcaaaggc gctatggcta cagctgatgc
     5881 tatctttcta tgtcgttttt aatttggtgg ttattgtaga gagtacgagt aatcaattaa
     5941 cgacaatcct atagagtgta aaagacgaat taaggattat atagaaaaag aatacgatta
     6001 caatctatct caaactttag atgaaatccg tcctaactat cgttttaacg aaacatgtca
     6061 ggaaactgtc cctcaagcca ttatcgcctt tcttgaaagt agagacttcg aagatgcgat
     6121 aagaaatgcc atctcacttg gtggcgacag tgatactctc gcagcaatca cttgtagcat
     6181 agcagaggca gcttacggta ttcctgattg gatcaaggat aaggcctatt cttacttgga
     6241 tgaaccctta aaggatgtag ttaggcgatg ggaaaataga ataaaagtgt attaatctcc
     6301 agtacgtcag atttctcttt tctgtatttt cattgtataa taggattaca tttacttgca
     6361 tacgacgaaa tgtaaacatt tctatttaaa attaaggata aaatcaatga aaaaagcaat
     6421 ggtaattatc aaccctactt ctggtggcga gaaggctttg gattacaaag aaaagctgga
     6481 gaataaagca aaagaatact ttgaatatgt tgaaaccaaa attaccgaaa aagcgctgga
     6541 tgcaacacat tttgctgaag aagcttctcg tgagcagtat gatgcagtgg ttgtgtttgg
     6601 tggagatggg actgtcaatg aagtcatttc aggtattgat gagagagact acattcctaa
     6661 gttagggatt atcccaggcg gtacgggtaa cctcattaca aaacttttgg aaatcaatca
     6721 agacatcgat ggcgcaattg acgaactgga ttttgattta accaataaga ttgatatcgg
     6781 taaagcaaat gacaactatt ttggttatat ctttagtatc ggttctctgc ctgaggcgat
     6841 tcacaatgtt gaaatagagg acaaaacaaa acaaggtatt ttagcctatg ctgtaaatac
     6901 tatgaagtct gtcatgacag atcaggtctt taacattaag gttgagacag aaaatggaaa
     6961 ttatgttggt gaagctagcc atgttttggt ccttttgaca aattacttcg ctgataagaa
     7021 aatctttgaa gaaaacaagg acggctatgc caacattttg attctgaaag atgcctctat
     7081 attctccaaa ttatccgtca ttcctgattt attaaaaggg gatgttatcg caaatgataa
     7141 tatcgagtat atcaaagcgc gtaatattaa aatctcttca gatagtgaat tggagtcaga
     7201 tgttgacgga gataaatcag ataacctacc tgtagaaatc aaagtcctag ctcagcgagt
     7261 agaagtattt tcaaaaccga aagtagaagt attttcaaaa ccgaaagagg attagtatat
     7321 agagaaagcc ttttttaagg ctttttgtat actttaaaag atagttcctt taacaacgga
     7381 cattccttgc aaatagttca caaaaatagt atactggatt cattgagttt gaaaacgttt
     7441 gcgtaaaatt tgaatgaata ctttaggaga taaattgatg gaattgagtg ctatttacca
     7501 taggactgag tcggagtatg cctatcttta taaggataag aaactccata ttcgaattcg
     7561 aactaagaaa ggggacattg aaagcatcaa cttgcactat ggggaccctt ttatctttat
     7621 ggaggagttt tatcaggata caaaagaaat ggtcaagata acttctggta ccttatttga
     7681 ccattggcag gttgaagtgt cagttgactt tgcacgtatc cagtatcttt ttgagctcag
     7741 agatacagaa ggtcaaaata ttttgtatgg cgataaaggg tgtgtggaaa attctctaga
     7801 aaatcttcat gcaattggga atggatttaa gttgccttat cttcatgaga ttgatgcctg
     7861 caaggttcct gactgggttt caaatacggt atggtatcag atatttcctg aaagatttgc
     7921 caatggcaat gctctattaa acccagaagg gactttagac tgggattcat ctgtcacacc
     7981 taagagcgat gatttctttg gtggtgattt acaggggatt attgatcata tggattactt
     8041 gcaagacttg ggtattactg gactatatct ttgtcccatc tttgaatcta caagcaatca
     8101 caagtacaat acgacagatt actttgaaat tgaccgtcat tttggagaca aggagacctt
     8161 tcgggaactg gtggatcaag cgcatcatcg tggcatgaaa gtcatgctgg atgcggtatt
     8221 taatcatatt ggttcgcaat ctcttcaatg gaaaaatgtc gtcaaaaatg gtgaacagtc
     8281 tgcttataag gattggttcc atattcaaca attcccagtg acaactgaaa agctagttaa
     8341 taagagagac ttaccctatc atgtttttgg tttcgaggac tatatgccta agctaaatac
     8401 agccaatcca gaggtcaaga attatctttt aaaggttgcg acttattgga ttgaagagtt
     8461 taatatcgat gcttggcgtt tggatgtggc taatgagatt gaccatcagt tctggaagga
     8521 ttttcgtaag gcagttttag ctaaaaatcc tgatctttat atcctaggag aagtctggca
     8581 tacatctcag ccttggctaa atggagatga gttccatgcc gtcatgaatt atcctttatc
     8641 tgatagtatc aaggactatt tcttacgagg aattaagaag acagaccagt tcatcgatga
     8701 aatcaatgga gagtctatgt attacaagca gcagatttca gaggtcatgt ttaatctctt
     8761 ggattcacat gatacagagc gaatcctgtg gacggccaat gaagatgttc aactggttaa
     8821 atcagcctta gcctttctct ttttacaaaa aggaacaccg tgcatttatt acggaaccga
     8881 gctagccttg actggaggac cagatccaga ttgtcgtcgt tgtatgcctt gggaacgtgt
     8941 atcaagtgac aatgatatgc tgaactttat gaagaggctg attaagattc ggaaatacgc
     9001 gtcagtaatc atttcgcatg gcaagtatag ccttcaagaa atcaaatctg atctagtagc
     9061 tctggaatgg aaatacgaag gacggatcct caaagcaata ttcaaccaat caacagaaga
     9121 ttatctttta gagaaagaag cagtagcact agcaagcaat tgccaagaat tggagaatca
     9181 gcttgtcatc tctccagatg gatttgtgat tttctaaaaa ctagttgatg aagattatgg
     9241 tacatttcat atcttatata gtataataag gctagttact aaacttgtaa aggagaactt
     9301 aaatgaattg tagaggacat gaaacaagac aaagaattgt tagagatttt gaagtttagc
     9361 ctaaagcaca tattaagctg ttagcaaatc aacaaaaaca tagtgatgca ggagcaacta
     9421 ttgaagatga atattatgta tttatcgctg agagtaaaat tgatggcaag aaggaagtta
     9481 ttcagtgttg catgggtgcg gcaagggatt ttttagaact aattaatcac aaagggctac
     9541 ctctttttaa tccgcttgta ggtgattctc atgtaaataa tagacaagaa tatgacaata
     9601 cagggagtgg aaatttacaa cctgaaaagt ggaatgaaac tgcaaagcag ctttataatg
     9661 ttataatgtg gttgattatt ttatggaatg ctaagccgga tacaccttta tttaatttta
     9721 aagacgaagt aattaagtat aaaacatatg agccttttga aagcagtata aaattggtat
     9781 caatcaatga gtaacaaagt atcagcatga ttcgaaacat ttacttgtaa tttgcggagg
     9841 aacatcaata tggatggaat aacaaaagat tttataaaaa cggctaaact aatgaaacaa
     9901 ttatggcccc aattgaccga taaagaagct attgatgaag taaaaaaata tacgaatggc
     9961 aaaaatactg caatctttac tgaagttgaa ggtgacacaa ttgtaggtct agcactatgt
    10021 tcactcagat ttgattatgt tgaaggttgt aaatatagtc ctgttggatt cttagaaggg
    10081 attattgttg acgaggaata tcgtttaaag gatattgcta aaaatctctg tacaaaatgt
    10141 gaggaatggg cgaaaaataa aggatgtaag gaatttgcaa gtgactgtac tttaacgaat
    10201 acggattcta taagatttca tctcaatatt ggatttcagg aggcaaatag aattattcat
    10261 tttaagaaaa aattataatt tagaaacgtg aataaacttg tttaaacttt atgtatcttt
    10321 agaaagtgtg ttaacttgaa agaacaaatt tttttgatgg gtgggaatcc cccaatgaag
    10381 aaatatagta ttgttgataa aattgtatta tcaaccaaga ttaaaagaat tatcattttt
    10441 acagtttttc gagaaaattg ggaaccgtac atgaaaaagt acacggaagt ttttcaaagt
    10501 caatttccta atctaaacat tgattacttg ctcctggaca ctgagcagat tgatcttgat
    10561 agctatctag atgctgacat aattatcatc ggtggtggaa atacggaaaa atatattgct
    10621 aacttatgtt aatcaggagt tcaaaagtta tatcgatcat atgcttaata aagaggcaaa
    10681 aattatagga ttttctgcag gagccctact attaggagaa aaagtctatg tctcacctaa
    10741 tgataattca gatcatcaga taaagataaa aaatggatta ggactcttta gtcagttttt
    10801 aattagtgtc cattatgatt cctggaatga taaagcaaat aaggatagag ctgaagaact
    10861 cgttaatgtt cccataattc cactaaatga tcattcttgt cttgtattgg ataaacttgg
    10921 aaacatcata gagaaaattg actaactttc ataatgtaaa aatggatcta ggaaataaaa
    10981 gtgtagacga actggatagg ttactagtga aaactgcaaa aagtgttgta aagtgaatcg
    11041 gagtgtgctt gatggatttt agtagtaaga tagccataaa taagggctgg tcagatgata
    11101 aaaaatattg tgtgacagat caaaatcagt aaaaatattt cttgcgtgtt tctgataagt
    11161 cgaagttaga ttataaaaaa atttgaattt gatatgatgg agaaagtagc ttctcttgga
    11221 gttccgatgt gtaaaccaat tagcattgaa ctctgcgatg acgaagtaca ttctttacac
    11281 gaatggatag acggaagaga tgcaatagat agcattttag cttattcaga aaaccaacaa
    11341 tacacatatg gtgtagaagc aggaaagata cttagaaaga ttcatacaat tcctgctaca
    11401 gaagtttgtg aagattggga aattttttta atctaaaaat tgatgataaa atctccaacg
    11461 aaatgatatg gtaagtccga aacgctcagt gtgtaagctt gttgctaaaa gcgtaaaaac
    11521 cttggaacga aaggaataat agacttcctg cgaaacaaaa atacaataca ataaaactat
    11581 ggatgatgaa gcaagtaaac aattaagcga tagccgtttc aagatccttg taggtgttca
    11641 gcgcacgact tttgaagaga tgttagctgt gttaaaaaca gcttatcaac gtaaacgcgc
    11701 aaaaggtgga cgaaaaagca aattaagcct agacgatctc cttatggtaa ctattcaata
    11761 catgcgagaa tagagcactt atgaacaaat tgcggctgat tttggcattc acgaaagcaa
    11821 cttaatccgt cggagtcaat gggttgaagc aactcttatt caaaatggtt ttacgatttc
    11881 aaattctgcc ttaattctgt aaaaacagta aaattcgaag gattgtaagg taagagtttt
    11941 tttctttctg aaaaaatggt ataatagcaa tcaaaactag aaaataaaac ggaatttgga
    12001 acagatttgt ctgtatccta gtagagtggt gatactatga agattagtaa gaggcactta
    12061 ttaaattatt ccatcttgat tccctacttg cttttatcta ttttgggctt gattgtggtc
    12121 tattcgacca ccagtgctat tttaattgaa gaaggcaaga gcgccttgca gttggttcga
    12181 aaccaaggaa tcttttggat tgttagtttg atactgattg ccttaattta taaattgaga
    12241 ctagattttt tgagaaatga gcgactaatc attttagtta tattaataga aatgctttta
    12301 ttgttcttgg ctcgttttat tggtatttca gtaaacgggg catacggttg gatttcggtt
    12361 gcaggagtaa ctattcagcc agctgagtac ttaaaaatca ttattatttg gtatttagct
    12421 caccgattct ccaaacagca agaagaaata gctacttatg attttcaagt tttgactcaa
    12481 aatcaatggc ttccccgtgc ttttaatgat tggcgattcg ttctcctagt tctgattgga
    12541 agtttgggaa ttttccctga tttaggaaat gcgactattt tagtcttggt ttccttgatt
    12601 atgtatacag ttagtggaat cgcttatcgc tggttttcaa ccattctggc gctcgtatct
    12661 gccacttctg tctttgtctt gaccactatc agcctaatcg gtgttgagac cttttcaaaa
    12721 attccagtat ttggctatgt agccaagcgc tttagtgcct tttttaatcc ttttgccgat
    12781 cgtgctgatg caggtcacca gttagctaat tcttattttg ccatggtcaa tggtggttgg
    12841 tttggtctag gtcttggaaa ctcgattgaa aaacgaggtt atttgccaga agctcataca
    12901 gactttgtct tttctatcgt gattgaagaa tttggctttg ttggtgccag tcttatttta
    12961 gctctcttgt ttttcatgat tttgcggatt atcttggtcg gtatccgagc ggagaatcct
    13021 ttcaatgcca tggttgcact cggtgtcgga gggatgatgt tggttcaggt atttgtcaat
    13081 atcggaggga tttcgggctt gattccatct acaggagtga ctttcccttt cttatcccag
    13141 ggtggaaata gtcttctagt cttatcagtg gcagtagcct ttgtcttaaa tattgatgcc
    13201 agtgaaaaac gcgctaagtt gtaccgagaa ttggaaaatc aaccaatgaa ccttctgttg
    13261 aagtaggata aagaaaggat agtttatgtc tcttcaaaaa ttagaaaatt atagtaataa
    13321 aagtgttgtg caagaagaag tcttgattct aacagaatta ctggaagata ttactaaaaa
    13381 tatgcttgcc ccagagacct ttgaaaaaat aatacagttg aaagaattat caacgcagga
    13441 agattatcaa ggtctaaacc gtctagtgac tagcttatca aatgatgaaa tgg
//
LOCUS       DAVAGB010000131         6590 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ND6715
            SAMN08647788-rid20187413.guided.077, whole genome shotgun sequence.
ACCESSION   DAVAGB010000131 DAVAGB010000000
VERSION     DAVAGB010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08647788
            Sequence Read Archive: SRR6818081
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980986.1
            Genome Coverage       :: 36x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:47:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,184
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,018
            CDSs (with protein)               :: 2,018
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 73 of 119
            Pseudo Genes (incomplete)         :: 48 of 119
            Pseudo Genes (internal stop)      :: 23 of 119
            Pseudo Genes (multiple problems)  :: 21 of 119
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6590
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08647788-rid20187413.guided.077"
                     /strain="ND6715"
                     /serotype="23A"
                     /isolation_source="nasopharyngeal"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="USA"
                     /lat_lon="42.36 N 71.570 W"
                     /collection_date="2014"
                     /collected_by="HARVARD PILGRIM HEALTH CARE"
     gene            194..1228
                     /locus_tag="VQO19_002177"
     CDS             194..1228
                     /locus_tag="VQO19_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HET1350340.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKVLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALETPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAYVDAQE
                     QVIRFDYNKK"
     gene            1334..1597
                     /locus_tag="VQO19_002178"
     CDS             1334..1597
                     /locus_tag="VQO19_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350341.1"
                     /translation="MTKQKINRIVGSIGAFIGIIVFIAYIPQIIANLQGNKAQPFQPL
                     SAAISCLIWVIYGWTKEPKKDWILIIPNSAGVILGGITFLTSL"
     gene            complement(1682..2113)
                     /locus_tag="VQO19_002179"
                     /pseudo
     CDS             complement(1682..2113)
                     /locus_tag="VQO19_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166574.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
     gene            2663..2833
                     /locus_tag="VQO19_002180"
     CDS             2663..2833
                     /locus_tag="VQO19_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HET1350342.1"
                     /translation="MKYFEVELENPDEFLKLQTEDFVKANRLLLRKIIQSVTVYEENF
                     VISFKSGIELEV"
     gene            3219..4436
                     /gene="mef(A)"
                     /locus_tag="VQO19_002181"
     CDS             3219..4436
                     /gene="mef(A)"
                     /locus_tag="VQO19_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012102963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide efflux MFS transporter Mef(A)"
                     /protein_id="HET1350343.1"
                     /translation="MEKYNNWKRKFYAIWAGQAVSLITSAILQMAIIFYLTEKTGSAM
                     VLSMASLVGFLPYAILGPAIGVLVDRHDRKKIMIGADLIIAAAGAVLAIVAFCMELPV
                     WMIMIVLFIRSIGTAFHTPALNAVTPLLVPEEQLTKCAGYSQSLQSISYIVSPAVAAL
                     LYSVWDLNAIIAIDVLGAVIASITVAIVRIPKLGNQVQSLEPNFIREMKEGVVVLRQN
                     KGLFALLLLGTLYTFVYMPINALFPLISMEHFNGTPVHISITEISFAFGMLAGGLLLG
                     RLGGFEKHVLLITSSFFIMGTSLAVSGILPPNGFVIFVVCCAIMGLSVPFYSGVQTAL
                     FQEKIKPEYLGRVFSLIGSIMSLAMPIGLILSGFFADKIGVNHWFLLSGILIIGIAIV
                     CQMITEVRKLDLK"
     gene            4457..5920
                     /gene="msr(D)"
                     /locus_tag="VQO19_002182"
     CDS             4457..5920
                     /gene="msr(D)"
                     /locus_tag="VQO19_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(D)"
                     /protein_id="HET1350344.1"
                     /translation="MELILKAKDIRVEFKGRDVLDINELEVYDYDRIGLVGANGAGKS
                     TLLRVLLGELTPPGCKMNRLGELAYIPQLDEVTLQEEKDFALVGKLGVEQLNIQTMSG
                     GEETRLKIAQALSAQVHGILADEPTSHLDREGIDFLIGQLKYFTGALLVISHDRYFLD
                     EIVDKIWELKDGKITEYWGNYSDYLRQKEEERKSQAAEYEQFIAERARLERAAEEKRK
                     QARKIEQKAKGSSKKKSTEDGGRLAHQKSIGSKEKKMYNAAKTLEHRIAALGKVEAPE
                     GIRRIRFRQSKALELHNPYPIVGAEINKVFGDKALFENASFQIPLGAKVALTGGNGIG
                     KTTLIQMILNHEEGISISPKAKIGYFAQNGYKYNSNQNVMEFMQKDCDYNISEIRSVL
                     ASMGFKQNDIGKSLSVLSGGEIIKLLLAKMLMGRYNILIMDEPSNFLDIPSLEALEIL
                     MKEYTGTIVFITHDKRLLENVADVVYEIRDKKINLKH"
     gene            complement(6038..6337)
                     /locus_tag="VQO19_002183"
     CDS             complement(6038..6337)
                     /locus_tag="VQO19_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350345.1"
                     /translation="MNQLEFQRNHLQMDYYSESYQDFERDFYRYSNMNIPLTFLTDDI
                     LKTMATSRKNYFVLNKEKSRDNRDHFFIFEVSTVDENPLIYHYTYKKTTIYLAEK"
     gene            complement(6324..>6590)
                     /locus_tag="VQO19_002184"
     CDS             complement(6324..>6590)
                     /locus_tag="VQO19_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET1350346.1"
                     /translation="LSDDTNKVTYMSDLSLEKKLLLLSQVYAGQLRTRIQVIEKNKRV
                     SYTGTIPSLTKDFILIKTTTGHINLKLKDIISIELVEEVLYESA"
BASE COUNT         2066 a         1097 c         1383 g         2044 t
ORIGIN      
        1 caatgaaaat caaagagcaa actaggaagc tagctgcagg ttgctcaaag cacagctttg
       61 aggttgcaaa taaaactgac gtggtttgaa gagattttcg aagagtatta aaagtattct
      121 tctgaaatcc cacatagctt tctcttatat tttgtgataa aataggctca atctatttct
      181 aggaggatga gatatggttt ctactattgg tattgttagt ttatctagtg gcattatcgg
      241 agaggatttt gtcaaacacg aagtggactt gggtatccaa cgtctcaagg ttctgggact
      301 caatcccatc tttttgcccc attcgttaaa aggattagac tttatcaagg accatcctga
      361 agctcgtgca gaggatttga ttcatgcctt ttctgatgat agcatcgaca tgatcctatg
      421 tgccatcggt ggagacgata cctatcgctt gctaccttat ctttttgaaa atgaccaact
      481 ccaaaaggtt atcaaacaaa aaatttttct tggcttctcg gatacaacca tgaaccacct
      541 catgttgcat aaattaggaa tcaagacttt ttatggtcaa tcctttttag cagacatttg
      601 tgaattagac aaagaaatgc tagcctatag ccttcactac tttaaagaat tgattgagac
      661 gggaagaatt tcagaaatcc gccctagtga cgtttggtat gaggaacgaa ctgattttag
      721 tcccacggcc ctggaaacac ctcgtgtcag tcatacaaat acaggttttg acttgttgca
      781 aggaagtgct cagttcgagg ggaaaatcct cggtggttgc ctcgaatccc tctacgatat
      841 ctttgacaac tctcgatacg cagatagcac ggagctctgc caaaaataca aacttttccc
      901 tgacttgtca gactgggaag ggaaaatcct cttgctcgaa acaagcgaag aaaagcctaa
      961 gccagaagac ttcaaaaaga tgttgctaac tttaaaggac actggcatat tcgcggtcat
     1021 caatggactc ttggtcggaa aacctatgga tgaaactttc catgacgact ataaagaggc
     1081 actattggat atcattgaca gcaatatccc gattgtctat aatctgaatg tcggccacgc
     1141 aactccaaga gccattgttc cctttggcgt tcacgcctat gtagatgcac aggaacaagt
     1201 cattcgcttt gactataaca aaaaataaat agtttctcta tttttgtgct tttgtattgg
     1261 ttttcgttac aatttgtatc tgaatttatt gcatttcgct aatttctatg gtatcctttt
     1321 gaaggaggtg tatatgacaa aacaaaaaat taatcgaatc gtaggttcta ttggtgcctt
     1381 tattggaatt atagtattta ttgcctacat acctcaaatt atcgctaatt tacaaggaaa
     1441 taaagctcaa ccatttcaac ctttatcagc tgctatatct tgcttaatct gggttattta
     1501 tggatggaca aaggaaccta agaaggattg gatactaatc attccaaatt cagctggtgt
     1561 tattttaggt ggaatcactt ttttgacttc actctaacaa atctaatagt atatataaaa
     1621 agctgggaaa aatttctcag cttttttcta tattctcaga tatgctagtt acctgtacac
     1681 actaattcct gcttttccat tcacaatcat tctcgtggtc atcaactagc cctgcagcct
     1741 gtagaaaaga caagacagcg actggtcctg tgaacttgaa gcctcgtttt ttgagatctt
     1801 tggctaattt ctcagacaaa ggtgttttag ctggggcttg gcggtaatcg ggaacatcgt
     1861 taacaatcgt tttcccctca acaaaagacc aaagataggc atcaaaagag ccatggtctt
     1921 cctgtagtcg tagaaaggct tgggcgttag cgcgtgtagc aaaaatcttg gctctatttc
     1981 ggatgatggc tggattatcc agcaagtctt ccaattcagt atcggtcatt tctgcgaccg
     2041 cttgaatttg atagccataa aatgcttctc ggaaagcttg acgtttgttg agcaccgttt
     2101 cccaagacag accatgttga ggcggtaagt ttgctagtca aggagtaaaa cgacgaagat
     2161 tagcatttac ttccgcccat gcgatagctg tccgtgattg acaagtgcta gcacgcagac
     2221 agaacggaga tagcgaaccg ctgagtgtgt cgctctgctc gtaaaagctt agaaaccttt
     2281 gaacgaaagg gataatgaaa gccttgattg caaggctttt tgctttatgg tgggtaagta
     2341 tcagagtgag aaaatttttg gaatgagtag aagtgatagc tagaaattat cagtttctat
     2401 ttccatttac cctgtgggta cgtgtttgtt tccattgaca aggagtttgt gggaatagaa
     2461 atgtacccac cttgtttgaa tcaagtgaag tgtagttgaa ggaaatctgt tgaaagcaat
     2521 acttcatttt accgaataag taataattta ggcaacttca aatcgattaa aaaaaactat
     2581 tttaaaggtt aagagtagac aaaaattgtc cactcttttt tgcaaactca atttatcaat
     2641 aaatgaaatg agggaatgta aaatgaaata ttttgaggtt gagttagaaa atcctgatga
     2701 atttttaaaa ctacaaacag aagattttgt gaaagctaat cgcttgctac taaggaagat
     2761 aatccagagc gttacagtct atgaagaaaa cttcgtcata tcctttaaat ctggcatcga
     2821 attggaagta tgagtctcat tccataactt ttatattgaa catatcatct tgttgtgtta
     2881 tactataaat tgatataaac aaagatgtag gaggaaccga aactatgaca gcctcaatgc
     2941 gtttaagata agctggcaat aaaaaaagca gaatctatac ccgatgatag gcttttttgt
     3001 tgtgcttatt tatacgatat tgagcattca ttagttacgg tgaggatatt ggttatttaa
     3061 ctataccttt atttaactat gtctttaata tgaatgtttc caaattgtat gtatgcagac
     3121 caaaagccac attgtggggt ttggcctgca ttttttattg cctagaatgc tattcaaaat
     3181 agaaattcaa gcaaaataat atgcaggaga taatataaat ggaaaaatac aacaattgga
     3241 aacgaaaatt ttatgcaata tgggcagggc aagcagtatc attaatcact agtgccatcc
     3301 tgcaaatggc gattattttt taccttacag aaaaaacagg atctgcgatg gtcttgtcta
     3361 tggcttcatt agtaggtttt ttaccctatg cgattttggg acctgccatt ggtgtgctag
     3421 tggatcgtca tgataggaag aagataatga ttggtgccga tttaattatc gcagcagctg
     3481 gtgcagtgct tgctattgtt gcattctgta tggagctacc tgtctggatg attatgatag
     3541 tattgtttat ccgtagcatt ggaacagctt ttcatacccc agcactcaat gcggttacac
     3601 cacttttagt accagaagaa cagctaacga aatgcgcagg ctatagtcag tctttgcagt
     3661 ctataagcta tattgttagt ccggcagttg cagcactctt atactccgtt tgggatttaa
     3721 atgctattat tgccatcgac gtattgggtg ctgtgattgc atctattacg gtagcaattg
     3781 tacgtatacc taagctgggt aatcaagtgc aaagtttaga accaaatttc ataagggaga
     3841 tgaaagaagg agttgtggtt ctgagacaaa acaaaggatt gtttgcctta ttactcttag
     3901 gaacactata tacttttgtt tatatgccaa tcaatgcact atttccttta ataagcatgg
     3961 aacactttaa tggaacgcct gtgcatattt ctattacgga aatttccttt gcatttggga
     4021 tgctagcagg aggcttatta ttaggaagat tagggggctt cgaaaagcat gtattactaa
     4081 taacaagttc attttttata atggggacca gtttagccgt ttcgggaata cttcctccaa
     4141 atggatttgt aatattcgta gtttgctgtg caataatggg gctttcggtg ccattttata
     4201 gcggtgtgca aacagctctt tttcaggaga aaattaagcc tgaatattta ggacgtgtat
     4261 tttctttgat cggaagtatc atgtcacttg ctatgccaat tgggttaatt ctttctggat
     4321 tctttgctga taaaatcggt gtaaatcatt ggtttttact atcaggtatt ttaattattg
     4381 gcattgctat agtttgccaa atgataactg aggttagaaa attagattta aaataaacaa
     4441 tattggagga aatgttatgg aattaatatt aaaagcaaaa gacattcgtg tggaattcaa
     4501 aggacgcgat gttttagata taaatgaatt agaagtatat gattatgacc gtattggttt
     4561 agtaggagca aatggtgctg gaaaaagcac tttactcagg gtacttttag gagaattaac
     4621 tcccccagga tgtaaaatga atcgtctggg tgaacttgcc tatattcccc agttggacga
     4681 agtaactctg caggaggaaa aagattttgc acttgtaggc aagctaggtg ttgagcaatt
     4741 aaatatacag actatgagcg gtggtgaaga aacaaggctt aaaatagcac aggccttatc
     4801 ggcacaggtt catggtattt tagcggatga acctacgagc catttagacc gtgaaggaat
     4861 tgattttcta ataggacagc taaaatattt tacaggtgca ctgttagtta ttagccatga
     4921 ccgctatttt cttgatgaaa tagtagataa aatatgggaa ctgaaagatg gcaaaatcac
     4981 tgagtattgg ggaaactatt ctgattatct tcgtcagaaa gaggaagaac gtaagagcca
     5041 agctgcagaa tacgaacaat ttattgcgga acgtgcccga ttggaaaggg ctgcggagga
     5101 aaagcgaaaa caggctcgta aaatagaaca gaaggcaaaa ggttcttcaa agaaaaaaag
     5161 tactgaagac ggagggcgtt tagctcatca aaaatcaata ggaagtaagg aaaaaaagat
     5221 gtataatgct gctaaaaccc tagagcacag gattgcggcc ttaggaaaag tagaagctcc
     5281 ggaaggcatt cgcagaattc gtttcaggca aagtaaagca ttggagctcc ataatccata
     5341 ccctatagtc ggtgcagaaa ttaataaagt atttggggat aaggctctgt ttgaaaatgc
     5401 atcttttcaa attccgttag gagcaaaagt ggcgttaact ggtggtaatg gaatcggaaa
     5461 aacaacttta atccaaatga tcttaaacca tgaagaagga atttctattt cgcctaaggc
     5521 aaaaataggt tactttgcac agaatggtta caagtacaac agtaatcaga atgttatgga
     5581 gtttatgcag aaggattgtg actacaatat atcagaaatt cgttcagtgc tagcatctat
     5641 ggggttcaaa cagaacgata ttggaaaaag tttatctgtt ttaagcggtg gagaaattat
     5701 aaaattgttg cttgctaaaa tgctcatggg tagatataac atcctaataa tggatgaacc
     5761 cagtaacttc cttgacatac caagtttaga ggctttggaa atactaatga aggagtacac
     5821 cggaactatc gtgtttatca cccacgataa acgattactc gaaaatgtag cagatgtagt
     5881 ttatgaaatt agagataaga aaataaatct gaaacattaa atttaaggta gtcgctggtc
     5941 agtatagtct gttctggttg gcgactccat tgttaaagag tataaagact ttagatttta
     6001 tgaatattaa aaataggaac agtcaattga actgctccta tttttctgct aaatatattg
     6061 tagttttctt atatgtataa tgatagatta gcggattctc atctacggta cttacttcaa
     6121 atatgaagaa gtgatcgcgg ttatctctgg acttttcctt attgaggaca aagtaattct
     6181 tacgtgaagt cgccattgtt tttaggatat catcagttag gaaggtcaat ggaatattca
     6241 tgttagagta gcggtagaag tcacgttcaa aatcttggta gctctcgcta taatagtcca
     6301 tttgtaggtg attacgctga aactcaagct gattcataga gcacctcctc gacaagttca
     6361 atactaataa tgtcttttaa tttcaaattg atgtgacctg ttgtagtttt tatcaaaatg
     6421 aaatctttgg tcagacttgg tattgttcca gtgtaggaaa cacgcttgtt tttttcaatc
     6481 acttgaatgc gtgtgcgtag ctgcccggcg tatacttgac tgaggagtaa taatttcttc
     6541 tctagtgata agtcagacat gtacgttact ttgtttgtat catcagagag
//
